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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12040612
log Bayes Factor = 11.6254
Chromosome 1   position 81,943,332  (GRCh37) Explore rs12040612 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.997 0.003 0.000
T81 Complications of procedures, not elsewhere classified
0.997 0.003 0.000
M05-M14 Inflammatory polyarthropathies
0.996 0.004 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.996 0.004 0.000
C15-C26 Malignant neoplasms of digestive organs
0.995 0.005 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.995 0.005 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.994 0.006 0.000
M20-M25 Other joint disorders
0.992 0.008 0.000
M06 Other rheumatoid arthritis
0.988 0.012 0.000
C78.7 Secondary malignant neoplasm of liver
0.985 0.015 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.983 0.017 0.000
M24 Other specific joint derangements
0.983 0.017 0.000
M06.9 Rheumatoid arthritis, unspecified
0.981 0.019 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.980 0.020 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.973 0.027 0.000
K82 Other diseases of gallbladder
0.971 0.029 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.971 0.029 0.000
K82.8 Other specified diseases of gallbladder
0.971 0.029 0.000
Chapter XI Diseases of the digestive system
0.970 0.030 0.000
M24.1 Other articular cartilage disorders
0.952 0.048 0.000
C78.2 Secondary malignant neoplasm of pleura
0.952 0.048 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.949 0.051 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.942 0.058 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.941 0.059 0.000
Y83.8 Other surgical procedures
0.940 0.060 0.000
M80-M85 Disorders of bone density and structure
0.935 0.065 0.000
C51-C58 Malignant neoplasms of female genital organs
0.935 0.065 0.000
M25 Other joint disorders, not elsewhere classified
0.934 0.066 0.000
S40-S49 Injuries to the shoulder and upper arm
0.929 0.071 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.928 0.072 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.926 0.074 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.926 0.074 0.000
C18 Malignant neoplasm of colon
0.925 0.075 0.000
C79 Secondary malignant neoplasm of other sites
0.924 0.076 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.924 0.076 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.916 0.084 0.000
C77.1 Intrathoracic lymph nodes
0.915 0.085 0.000
M65-M68 Disorders of synovium and tendon
0.915 0.085 0.000
C77.3 Axillary and upper limb lymph nodes
0.911 0.089 0.000
C20 Malignant neoplasm of rectum
0.911 0.089 0.000
M10 Gout
0.910 0.090 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.910 0.090 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.899 0.101 0.000
C77.2 Intra-abdominal lymph nodes
0.898 0.102 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.897 0.103 0.000
S70-S79 Injuries to the hip and thigh
0.896 0.104 0.000
C54 Malignant neoplasm of corpus uteri
0.893 0.107 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.890 0.110 0.000
Y84.8 Other medical procedures
0.888 0.112 0.000
T66-T78 Other and unspecified effects of external causes
0.885 0.115 0.000
K85 Acute pancreatitis
0.883 0.117 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.882 0.118 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.881 0.119 0.000
Y83.4 Other reconstructive surgery
0.874 0.126 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.873 0.127 0.000
M25.5 Pain in joint
0.873 0.127 0.000
Y83.6 Removal of other organ (partial) (total)
0.871 0.129 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.871 0.129 0.000
M24.2 Disorder of ligament
0.868 0.132 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.866 0.134 0.000
K83 Other diseases of biliary tract
0.866 0.134 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.864 0.136 0.000
C54.1 Endometrium
0.863 0.137 0.000
S90-S99 Injuries to the ankle and foot
0.863 0.137 0.000
C25 Malignant neoplasm of pancreas
0.855 0.145 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.854 0.146 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.854 0.146 0.000
D00-D09 In situ neoplasms
0.854 0.146 0.000
K86 Other diseases of pancreas
0.853 0.147 0.000
C77.9 Lymph node, unspecified
0.852 0.148 0.000
M10.9 Gout, unspecified
0.848 0.152 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.842 0.157 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.841 0.159 0.000
M40-M43 Deforming dorsopathies
0.836 0.164 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.836 0.164 0.000
C91 Lymphoid leukaemia
0.833 0.167 0.000
K40-K46 Hernia
0.831 0.169 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.830 0.170 0.000
L40-L45 Papulosquamous disorders
0.830 0.170 0.000
M25.56 Pain in joint (Lower leg)
0.828 0.172 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.828 0.172 0.000
Chapter XXII Codes for special purposes
0.827 0.173 0.000
K43 Ventral hernia
0.825 0.175 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.825 0.175 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.824 0.176 0.000
M81 Osteoporosis without pathological fracture
0.823 0.177 0.000
K85.9 Acute pancreatitis, unspecified
0.823 0.177 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.823 0.177 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.821 0.179 0.000
M25.57 Pain in joint (Ankle and foot)
0.818 0.182 0.000
C18.2 Ascending colon
0.818 0.182 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.814 0.186 0.000
T79-T79 Certain early complications of trauma
0.813 0.187 0.000
S43.0 Dislocation of shoulder joint
0.813 0.187 0.000
M10.99 Gout, unspecified (Site unspecified)
0.813 0.187 0.000
M84 Disorders of continuity of bone
0.810 0.190 0.000
C77.0 Lymph nodes of head, face and neck
0.809 0.191 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.808 0.192 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.804 0.196 0.000
T78 Adverse effects, not elsewhere classified
0.803 0.197 0.000
M11 Other crystal arthropathies
0.802 0.198 0.000
X60-X84 Intentional self-harm
0.801 0.199 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.801 0.199 0.000
S60-S69 Injuries to the wrist and hand
0.799 0.201 0.000
M06.3 Rheumatoid nodule
0.796 0.204 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.796 0.204 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.795 0.204 0.000
M45-M49 Spondylopathies
0.794 0.206 0.000
C17 Malignant neoplasm of small intestine
0.794 0.206 0.000
C18.0 Caecum
0.793 0.207 0.000
M65 Synovitis and tenosynovitis
0.792 0.208 0.000
S40 Superficial injury of shoulder and upper arm
0.792 0.208 0.000
M31 Other necrotising vasculopathies
0.789 0.211 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.788 0.212 0.000
C23 Malignant neoplasm of gallbladder
0.787 0.213 0.000
K55-K64 Other diseases of intestines
0.787 0.213 0.000
M67 Other disorders of synovium and tendon
0.787 0.213 0.000
C77.4 Inguinal and lower limb lymph nodes
0.786 0.214 0.000
D37.5 Rectum
0.786 0.214 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.782 0.218 0.000
D46 Myelodysplastic syndromes
0.782 0.218 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.781 0.219 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.779 0.221 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.778 0.222 0.000
Y83.3 Surgical operation with formation of external stoma
0.777 0.223 0.000
L40 Psoriasis
0.776 0.224 0.000
Y60.0 During surgical operation
0.776 0.224 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.776 0.224 0.000
M07 Psoriatic and enteropathic arthropathies
0.774 0.226 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.774 0.226 0.000
C81 Hodgkin's disease
0.774 0.226 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.771 0.229 0.000
W00-W19 Falls
0.771 0.229 0.000
S10-S19 Injuries to the neck
0.770 0.230 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.770 0.230 0.000
L89 Decubitus ulcer
0.770 0.230 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.768 0.232 0.000
W20-W49 Exposure to inanimate mechanical forces
0.768 0.232 0.000
K81 Cholecystitis
0.768 0.232 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.765 0.235 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.764 0.236 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.763 0.237 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.763 0.237 0.000
M22 Disorders of patella
0.761 0.238 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.761 0.239 0.000
Y84.1 Kidney dialysis
0.759 0.241 0.000
C79.6 Secondary malignant neoplasm of ovary
0.755 0.245 0.000
M25.4 Effusion of joint
0.755 0.245 0.000
K83.0 Cholangitis
0.753 0.247 0.000
S92 Fracture of foot, except ankle
0.752 0.248 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.750 0.250 0.000
K83.1 Obstruction of bile duct
0.749 0.251 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.749 0.251 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.746 0.254 0.000
D05 Carcinoma in situ of breast
0.745 0.255 0.000
Y40 Systemic antibiotics
0.745 0.255 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.744 0.256 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.743 0.257 0.000
D04 Carcinoma in situ of skin
0.742 0.258 0.000
M85 Other disorders of bone density and structure
0.741 0.259 0.000
S20-S29 Injuries to the thorax
0.739 0.261 0.000
K82.2 Perforation of gallbladder
0.739 0.261 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.738 0.262 0.000
C18.5 Splenic flexure
0.738 0.262 0.000
V80-V89 Other land transport accidents
0.737 0.263 0.000
M24.26 Disorder of ligament (Lower leg)
0.737 0.263 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.736 0.264 0.000
K86.8 Other specified diseases of pancreas
0.735 0.265 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.734 0.266 0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection
0.734 0.266 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.733 0.267 0.000
Y57 Other and unspecified drugs and medicaments
0.733 0.267 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.733 0.267 0.000
S70 Superficial injury of hip and thigh
0.732 0.268 0.000
Y83.5 Amputation of limb(s)
0.731 0.269 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.731 0.269 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.729 0.271 0.000
S72 Fracture of femur
0.729 0.271 0.000
L81 Other disorders of pigmentation
0.728 0.272 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.728 0.272 0.000
V40-V49 Car occupant injured in transport accident
0.727 0.273 0.000
M24.5 Contracture of joint
0.727 0.273 0.000
K63 Other diseases of intestine
0.726 0.274 0.000
C91.1 Chronic lymphocytic leukaemia
0.725 0.275 0.000
C83.0 Small cell (diffuse)
0.724 0.276 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.723 0.277 0.000
Y45.1 Salicylates
0.722 0.278 0.000
C77.5 Intrapelvic lymph nodes
0.721 0.279 0.000
C18.4 Transverse colon
0.721 0.279 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.721 0.279 0.000
M24.0 Loose body in joint
0.719 0.281 0.000
L40.5 Arthropathic psoriasis
0.719 0.281 0.000
L20-L30 Dermatitis and eczema
0.718 0.282 0.000
M25.9 Joint disorder, unspecified
0.717 0.283 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.717 0.283 0.000
D39.1 Ovary
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
D37.2 Small intestine
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
M25.3 Other instability of joint
0.716 0.284 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.716 0.284 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.715 0.285 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.715 0.285 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.715 0.285 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.715 0.285 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.715 0.285 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.715 0.285 0.000
C25.0 Head of pancreas
0.714 0.286 0.000
M14 Arthropathies in other diseases classified elsewhere
0.714 0.286 0.000
M12 Other specific arthropathies
0.714 0.286 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.714 0.286 0.000
M08 Juvenile arthritis
0.714 0.286 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.713 0.287 0.000
K63.9 Disease of intestine, unspecified
0.712 0.288 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.711 0.289 0.000
M34 Systemic sclerosis
0.711 0.289 0.000
M33 Dermatopolymyositis
0.711 0.289 0.000
M32 Systemic lupus erythematosus
0.711 0.289 0.000
M30 Polyarteritis nodosa and related conditions
0.711 0.289 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.711 0.289 0.000
M81.9 Osteoporosis, unspecified
0.710 0.290 0.000
M06.8 Other specified rheumatoid arthritis
0.708 0.291 0.000
M06.4 Inflammatory polyarthropathy
0.708 0.291 0.000
M06.2 Rheumatoid bursitis
0.708 0.291 0.000
M06.1 Adult-onset Still's disease
0.708 0.291 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.706 0.294 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.705 0.295 0.000
C95 Leukaemia of unspecified cell type
0.705 0.295 0.000
C94 Other leukaemias of specified cell type
0.705 0.295 0.000
C93 Monocytic leukaemia
0.705 0.295 0.000
C88 Malignant immunoproliferative diseases
0.705 0.295 0.000
C86 Other specified types of T/NK-cell lymphoma
0.705 0.295 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.705 0.295 0.000
M24.9 Joint derangement, unspecified
0.705 0.295 0.000
M24.7 Protrusio acetabuli
0.705 0.295 0.000
M24.6 Ankylosis of joint
0.705 0.295 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.705 0.295 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.705 0.295 0.000
S41 Open wound of shoulder and upper arm
0.704 0.295 0.000
C51 Malignant neoplasm of vulva
0.704 0.296 0.000
M25.54 Pain in joint (Hand)
0.704 0.296 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.703 0.297 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.703 0.297 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.703 0.297 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.703 0.297 0.000
M25.8 Other specified joint disorders
0.702 0.298 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.702 0.298 0.000
D37.4 Colon
0.702 0.298 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.701 0.299 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.701 0.299 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.701 0.299 0.000
K82.4 Cholesterolosis of gallbladder
0.701 0.299 0.000
C45 Mesothelioma
0.701 0.299 0.000
Y52 Agents primarily affecting the cardiovascular system
0.700 0.300 0.000
K65-K67 Diseases of peritoneum
0.700 0.300 0.000
T86 Failure and rejection of transplanted organs and tissues
0.699 0.300 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.699 0.301 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.698 0.302 0.000
K86.2 Cyst of pancreas
0.697 0.303 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.696 0.303 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.696 0.303 0.000
K82.3 Fistula of gallbladder
0.696 0.303 0.000
K82.0 Obstruction of gallbladder
0.696 0.303 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.695 0.305 0.000
D43.2 Brain, unspecified
0.694 0.306 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.694 0.306 0.000
T78.2 Anaphylactic shock, unspecified
0.693 0.307 0.000
M43 Other deforming dorsopathies
0.693 0.307 0.000
M25.0 Haemarthrosis
0.692 0.308 0.000
M23 Internal derangement of knee
0.690 0.310 0.000
K90-K93 Other diseases of the digestive system
0.690 0.310 0.000
M05 Seropositive rheumatoid arthritis
0.690 0.310 0.000
C21 Malignant neoplasm of anus and anal canal
0.688 0.312 0.000
M31.3 Wegener's granulomatosis
0.688 0.312 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.688 0.312 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.685 0.315 0.000
C78.0 Secondary malignant neoplasm of lung
0.684 0.315 0.000
Q80-Q89 Other congenital malformations
0.684 0.316 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.684 0.316 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.683 0.317 0.000
M24.18 Other articular cartilage disorders (Other)
0.683 0.317 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.683 0.317 0.000
M24.14 Other articular cartilage disorders (Hand)
0.683 0.317 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.683 0.317 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.683 0.317 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.683 0.317 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.683 0.317 0.000
C25.9 Pancreas, unspecified
0.683 0.317 0.000
C18.3 Hepatic flexure
0.682 0.318 0.000
M21 Other acquired deformities of limbs
0.682 0.318 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.682 0.318 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.681 0.319 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.681 0.319 0.000
Y43 Primarily systemic agents
0.680 0.320 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.679 0.320 0.000
C53 Malignant neoplasm of cervix uteri
0.679 0.321 0.000
K82.9 Disease of gallbladder, unspecified
0.679 0.321 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.679 0.321 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.678 0.322 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.677 0.323 0.000
M06.0 Seronegative rheumatoid arthritis
0.676 0.324 0.000
D04.7 Skin of lower limb, including hip
0.676 0.324 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.675 0.325 0.000
L10-L14 Bullous disorders
0.675 0.325 0.000
Y59 Other and unspecified vaccines and biological substances
0.675 0.325 0.000
Y58 Bacterial vaccines
0.675 0.325 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.675 0.325 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.675 0.325 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.675 0.325 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.675 0.325 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.675 0.325 0.000
Y48 Anaesthetics and therapeutic gases
0.675 0.325 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.675 0.325 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.675 0.325 0.000
Y45.2 Propionic acid derivatives
0.674 0.326 0.000
M91-M94 Chondropathies
0.673 0.327 0.000
M83 Adult osteomalacia
0.670 0.329 0.000
M82 Osteoporosis in diseases classified elsewhere
0.670 0.329 0.000
L82 Seborrhoeic keratosis
0.671 0.329 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.670 0.330 0.000
C58 Malignant neoplasm of placenta
0.670 0.330 0.000
C52 Malignant neoplasm of vagina
0.670 0.330 0.000
M25.2 Flail joint
0.670 0.330 0.000
M25.1 Fistula of joint
0.670 0.330 0.000
L81.4 Other melanin hyperpigmentation
0.670 0.330 0.000
S79 Other and unspecified injuries of hip and thigh
0.669 0.331 0.000
T85.2 Mechanical complication of intraocular lens
0.669 0.331 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.668 0.332 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.667 0.332 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.667 0.333 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.667 0.333 0.000
C80 Malignant neoplasm without specification of site
0.667 0.333 0.000
M45 Ankylosing spondylitis
0.667 0.333 0.000
S48 Traumatic amputation of shoulder and upper arm
0.666 0.334 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.666 0.334 0.000
S44 Injury of nerves at shoulder and upper arm level
0.666 0.334 0.000
S47 Crushing injury of shoulder and upper arm
0.666 0.334 0.000
K63.1 Perforation of intestine (nontraumatic)
0.665 0.335 0.000
T81.9 Unspecified complication of procedure
0.665 0.335 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.664 0.336 0.000
L83 Acanthosis nigricans
0.664 0.336 0.000
Y84.9 Medical procedure, unspecified
0.664 0.336 0.000
Y84.7 Blood-sampling
0.664 0.336 0.000
Y84.5 Insertion of gastric or duodenal sound
0.664 0.336 0.000
Y84.4 Aspiration of fluid
0.664 0.336 0.000
Y84.3 Shock therapy
0.664 0.336 0.000
C18.8 Overlapping lesion of colon
0.663 0.337 0.000
C18.1 Appendix
0.663 0.337 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.663 0.337 0.000
M11.2 Other chondrocalcinosis
0.663 0.337 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.662 0.337 0.000
C82.6 Cutaneous follicle centre lymphoma
0.662 0.338 0.000
C82.5 Diffuse follicle centre lymphoma
0.662 0.338 0.000
C82.4 Follicular lymphoma grade IIIb
0.662 0.338 0.000
C82.3 Follicular lymphoma grade IIIa
0.662 0.338 0.000
C82.2 Large cell, follicular
0.662 0.338 0.000
C82.0 Small cleaved cell, follicular
0.662 0.338 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.662 0.338 0.000
L60-L75 Disorders of skin appendages
0.661 0.339 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.660 0.340 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.660 0.340 0.000
D05.1 Intraductal carcinoma in situ
0.659 0.341 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.659 0.341 0.000
M25.59 Pain in joint (Site unspecified)
0.659 0.341 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.658 0.341 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.658 0.342 0.000
M06.34 Rheumatoid nodule (Hand)
0.658 0.342 0.000
C18.6 Descending colon
0.658 0.342 0.000
M81.4 Drug-induced osteoporosis
0.658 0.342 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.657 0.343 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.656 0.344 0.000
M66 Spontaneous rupture of synovium and tendon
0.656 0.344 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.655 0.345 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.655 0.345 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.653 0.347 0.000
W13 Fall from, out of or through building or structure
0.653 0.347 0.000
M65.3 Trigger finger
0.653 0.347 0.000
M10.4 Other secondary gout
0.652 0.347 0.000
M10.3 Gout due to impairment of renal function
0.652 0.347 0.000
M10.2 Drug-induced gout
0.652 0.347 0.000
M10.1 Lead-induced gout
0.652 0.347 0.000
M10.0 Idiopathic gout
0.652 0.347 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.652 0.348 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.651 0.349 0.000
K86.3 Pseudocyst of pancreas
0.651 0.349 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.651 0.349 0.000
C17.2 Ileum
0.650 0.349 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.650 0.350 0.000
K57 Diverticular disease of intestine
0.649 0.351 0.000
S90 Superficial injury of ankle and foot
0.649 0.351 0.000
T31 Burns classified according to extent of body surface involved
0.649 0.351 0.000
M67.8 Other specified disorders of synovium and tendon
0.649 0.351 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.648 0.352 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.648 0.352 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.647 0.353 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.647 0.353 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.646 0.354 0.000
K81.1 Chronic cholecystitis
0.646 0.354 0.000
L89.1 Stage II decubitus ulcer
0.645 0.355 0.000
Y65 Other misadventures during surgical and medical care
0.645 0.355 0.000
Y64 Contaminated medical or biological substances
0.645 0.355 0.000
Y63 Failure in dosage during surgical and medical care
0.645 0.355 0.000
Y62 Failure of sterile precautions during surgical and medical care
0.645 0.355 0.000
Y61 Foreign object accidentally left in body during surgical and medical care
0.645 0.355 0.000
Y69 Unspecified misadventure during surgical and medical care
0.645 0.355 0.000
Y66 Nonadministration of surgical and medical care
0.645 0.355 0.000
T90 Sequelae of injuries of head
0.645 0.355 0.000
C85.1 B-cell lymphoma, unspecified
0.644 0.356 0.000
T78.3 Angioneurotic oedema
0.643 0.357 0.000
M41 Scoliosis
0.643 0.357 0.000
S78 Traumatic amputation of hip and thigh
0.642 0.358 0.000
S77 Crushing injury of hip and thigh
0.642 0.358 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.642 0.358 0.000
S75 Injury of blood vessels at hip and thigh level
0.642 0.358 0.000
S74 Injury of nerves at hip and thigh level
0.642 0.358 0.000
S71 Open wound of hip and thigh
0.642 0.358 0.000
M35 Other systemic involvement of connective tissue
0.642 0.358 0.000
V20-V29 Motorcycle rider injured in transport accident
0.642 0.358 0.000
S50-S59 Injuries to the elbow and forearm
0.641 0.358 0.000
C54.9 Corpus uteri, unspecified
0.640 0.360 0.000
C54.8 Overlapping lesion of corpus uteri
0.640 0.360 0.000
C54.3 Fundus uteri
0.640 0.360 0.000
C54.2 Myometrium
0.640 0.360 0.000
C54.0 Isthmus uteri
0.640 0.360 0.000
C83.3 Large cell (diffuse)
0.639 0.361 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.639 0.361 0.000
M67.1 Other contracture of tendon (sheath)
0.638 0.362 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.638 0.362 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.638 0.362 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.638 0.362 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.637 0.363 0.000
S43.1 Dislocation of acromioclavicular joint
0.636 0.364 0.000
L40.9 Psoriasis, unspecified
0.636 0.364 0.000
C79.2 Secondary malignant neoplasm of skin
0.636 0.364 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.635 0.365 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.635 0.365 0.000
T75 Effects of other external causes
0.635 0.365 0.000
T74 Maltreatment syndromes
0.635 0.365 0.000
T73 Effects of other deprivation
0.635 0.365 0.000
T70 Effects of air pressure and water pressure
0.635 0.365 0.000
T69 Other effects of reduced temperature
0.635 0.365 0.000
T67 Effects of heat and light
0.635 0.365 0.000
T71 Asphyxiation
0.635 0.365 0.000
T68 Hypothermia
0.635 0.365 0.000
T66 Unspecified effects of radiation
0.635 0.365 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.635 0.365 0.000
Y84.6 Urinary catheterisation
0.635 0.365 0.000
K85.8 Other acute pancreatitis
0.633 0.367 0.000
K85.3 Drug-induced acute pancreatitis
0.633 0.367 0.000
K85.2 Alcohol-induced acute pancreatitis
0.633 0.367 0.000
K85.0 Idiopathic acute pancreatitis
0.633 0.367 0.000
D37.9 Digestive organ, unspecified
0.633 0.367 0.000
D37.6 Liver, gallbladder and bile ducts
0.633 0.367 0.000
D37.3 Appendix
0.633 0.367 0.000
D37.0 Lip, oral cavity and pharynx
0.633 0.367 0.000
Y40.3 Macrolides
0.632 0.368 0.000
V10-V19 Pedal cyclist injured in transport accident
0.631 0.369 0.000
D37.7 Other digestive organs
0.631 0.369 0.000
C18.9 Colon, unspecified
0.630 0.370 0.000
W10 Fall on and from stairs and steps
0.630 0.370 0.000
C15 Malignant neoplasm of oesophagus
0.629 0.371 0.000
K86.9 Disease of pancreas, unspecified
0.629 0.371 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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