TreeWAS – Variant ID: rs12042319

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.000	0.000	1.000
E78.5 Hyperlipidaemia, unspecified	0.000	0.000	1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.001	0.999
E78.1 Pure hyperglyceridaemia	0.000	0.138	0.862
E78.6 Lipoprotein deficiency	0.000	0.272	0.728
E78.3 Hyperchylomicronaemia	0.000	0.283	0.716
E78.8 Other disorders of lipoprotein metabolism	0.000	0.308	0.692
E78.4 Other hyperlipidaemia	0.000	0.332	0.668
E78.2 Mixed hyperlipidaemia	0.000	0.499	0.501
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.531	0.469
E89.0 Postprocedural hypothyroidism	0.000	0.654	0.346
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.671	0.329
E70-E90 Metabolic disorders	0.000	0.672	0.328
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.735	0.265
E79 Disorders of purine and pyrimidine metabolism	0.000	0.746	0.253
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.751	0.249
E84 Cystic fibrosis	0.000	0.760	0.240
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.764	0.236
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.764	0.236
E89.5 Postprocedural testicular hypofunction	0.000	0.764	0.236
E77 Disorders of glycoprotein metabolism	0.000	0.765	0.235
E76 Disorders of glycosaminoglycan metabolism	0.000	0.765	0.235
E72 Other disorders of amino-acid metabolism	0.000	0.765	0.235
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.765	0.235
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.765	0.235
E89.3 Postprocedural hypopituitarism	0.000	0.766	0.234
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.773	0.227
E85 Amyloidosis	0.000	0.784	0.216
E89.1 Postprocedural hypoinsulinaemia	0.000	0.787	0.213
E80.4 Gilbert's syndrome	0.000	0.787	0.213
E73 Lactose intolerance	0.000	0.791	0.209
E80.1 Porphyria cutanea tarda	0.000	0.793	0.207
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.799	0.200
E89.2 Postprocedural hypoparathyroidism	0.000	0.801	0.199
E75.5 Other lipid storage disorders	0.000	0.807	0.193
E70 Disorders of aromatic amino-acid metabolism	0.000	0.809	0.191
E80.2 Other porphyria	0.000	0.810	0.190
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.810	0.190
E80.5 Crigler-Najjar syndrome	0.000	0.810	0.190
E80.3 Defects of catalase and peroxydase	0.000	0.810	0.190
E80.0 Hereditary erythropoietic porphyria	0.000	0.810	0.190
E89.4 Postprocedural ovarian failure	0.000	0.813	0.186
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.818	0.182
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.818	0.182
E79.1 Lesch-Nyhan syndrome	0.000	0.818	0.182
E80.6 Other disorders of bilirubin metabolism	0.000	0.820	0.180
E75.6 Lipid storage disorder, unspecified	0.000	0.821	0.179
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.821	0.179
E75.3 Sphingolipidosis, unspecified	0.000	0.821	0.179
E75.2 Other sphingolipidosis	0.000	0.821	0.179
E75.1 Other gangliosidosis	0.000	0.821	0.179
E75.0 GM2 gangliosidosis	0.000	0.821	0.179
E84.9 Cystic fibrosis, unspecified	0.000	0.822	0.177
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.827	0.173
E84.8 Cystic fibrosis with other manifestations	0.000	0.828	0.172
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.828	0.172
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.828	0.172
E87.6 Hypokalaemia	0.000	0.829	0.171
E74 Other disorders of carbohydrate metabolism	0.000	0.830	0.169
E71.3 Disorders of fatty-acid metabolism	0.000	0.831	0.169
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.831	0.169
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.831	0.169
E71.0 Maple-syrup-urine disease	0.000	0.831	0.169
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.831	0.169
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.831	0.169
E72.5 Disorders of glycine metabolism	0.000	0.831	0.169
E72.4 Disorders of ornithine metabolism	0.000	0.831	0.169
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.831	0.169
E72.2 Disorders of urea cycle metabolism	0.000	0.831	0.169
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.831	0.169
E72.0 Disorders of amino-acid transport	0.000	0.831	0.169
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.831	0.169
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.831	0.169
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.831	0.169
E76.2 Other mucopolysaccharidoses	0.000	0.831	0.169
E76.1 Mucopolysaccharidosis, type II	0.000	0.831	0.169
E76.0 Mucopolysaccharidosis, type I	0.000	0.831	0.169
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.831	0.169
E77.8 Other disorders of glycoprotein metabolism	0.000	0.831	0.169
E77.1 Defects in glycoprotein degradation	0.000	0.831	0.169
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.831	0.169
E85.3 Secondary systemic amyloidosis	0.000	0.837	0.163
E85.8 Other amyloidosis	0.000	0.845	0.155
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.845	0.155
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.845	0.155
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.845	0.155
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.849	0.151
E73.8 Other lactose intolerance	0.000	0.850	0.150
E73.1 Secondary lactase deficiency	0.000	0.850	0.150
E73.0 Congenital lactase deficiency	0.000	0.850	0.150
E85.9 Amyloidosis, unspecified	0.000	0.853	0.146
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.863	0.137
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.863	0.137
E70.2 Disorders of tyrosine metabolism	0.000	0.863	0.137
E70.1 Other hyperphenylalaninaemias	0.000	0.863	0.137
E70.0 Classical phenylketonuria	0.000	0.863	0.137
E87.5 Hyperkalaemia	0.000	0.864	0.136
E85.4 Organ-limited amyloidosis	0.000	0.866	0.134
E87.4 Mixed disorder of acid-base balance	0.000	0.875	0.124
E73.9 Lactose intolerance, unspecified	0.000	0.876	0.124
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.878	0.122
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.878	0.122
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.878	0.122
E74.2 Disorders of galactose metabolism	0.000	0.878	0.122
E74.1 Disorders of fructose metabolism	0.000	0.878	0.122
E88 Other metabolic disorders	0.000	0.882	0.118
E74.0 Glycogen storage disease	0.001	0.904	0.096
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.904	0.095
E70.3 Albinism	0.001	0.907	0.092
E83 Disorders of mineral metabolism	0.000	0.914	0.086
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.915	0.085
E88.3 Tumour lysis syndrome	0.000	0.916	0.084
E88.8 Other specified metabolic disorders	0.000	0.919	0.080
E87.0 Hyperosmolality and hypernatraemia	0.000	0.920	0.080
E88.9 Metabolic disorder, unspecified	0.000	0.921	0.079
E87.3 Alkalosis	0.000	0.927	0.073
E87.7 Fluid overload	0.000	0.927	0.073
E83.5 Disorders of calcium metabolism	0.000	0.934	0.066
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.938	0.062
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.938	0.062
E83.8 Other disorders of mineral metabolism	0.000	0.938	0.062
E83.2 Disorders of zinc metabolism	0.000	0.938	0.062
E83.0 Disorders of copper metabolism	0.000	0.938	0.062
E10.3 With ophthalmic complications	0.000	0.938	0.062
E10 Insulin-dependent diabetes mellitus	0.000	0.941	0.059
E83.4 Disorders of magnesium metabolism	0.000	0.945	0.055
E10.6 With other specified complications	0.000	0.946	0.054
E10.0 With coma	0.000	0.947	0.053
E88.2 Lipomatosis, not elsewhere classified	0.001	0.948	0.051
E10.9 Without complications	0.000	0.950	0.050
E10.4 With neurological complications	0.000	0.953	0.047
E10.7 With multiple complications	0.000	0.957	0.042
E10.1 With ketoacidosis	0.000	0.958	0.042
E10.5 With peripheral circulatory complications	0.000	0.959	0.041
E10-E14 Diabetes mellitus	0.000	0.960	0.040
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.961	0.039
E10.8 With unspecified complications	0.000	0.967	0.033
E83.3 Disorders of phosphorus metabolism	0.000	0.969	0.031
G45.9 Transient cerebral ischaemic attack, unspecified	0.031	0.969	0.000
E10.2 With renal complications	0.000	0.969	0.030
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.970	0.030
E12 Malnutrition-related diabetes mellitus	0.000	0.971	0.029
E13 Other specified diabetes mellitus	0.000	0.972	0.028
E86 Volume depletion	0.000	0.973	0.027
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.975	0.025
E40-E46 Malnutrition	0.000	0.975	0.025
E16 Other disorders of pancreatic internal secretion	0.000	0.976	0.023
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.977	0.023
E15 Nondiabetic hypoglycaemic coma	0.000	0.978	0.022
E12.9 Without complications	0.000	0.979	0.021
E12.8 With unspecified complications	0.000	0.979	0.021
E12.7 With multiple complications	0.000	0.979	0.021
E12.6 With other specified complications	0.000	0.979	0.021
E12.5 With peripheral circulatory complications	0.000	0.979	0.021
E12.4 With neurological complications	0.000	0.979	0.021
E12.3 With ophthalmic complications	0.000	0.979	0.021
E12.2 With renal complications	0.000	0.979	0.021
E12.1 With ketoacidosis	0.000	0.979	0.021
E12.0 With coma	0.000	0.979	0.021
E13.3 With ophthalmic complications	0.000	0.980	0.020
E13.8 With unspecified complications	0.000	0.980	0.020
E13.7 With multiple complications	0.000	0.980	0.020
E13.6 With other specified complications	0.000	0.980	0.020
E13.5 With peripheral circulatory complications	0.000	0.980	0.020
E13.4 With neurological complications	0.000	0.980	0.020
E13.2 With renal complications	0.000	0.980	0.020
E13.1 With ketoacidosis	0.000	0.980	0.020
E13.0 With coma	0.000	0.980	0.020
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.020	0.980	0.000
E13.9 Without complications	0.000	0.981	0.019
M80.9 Unspecified osteoporosis with pathological fracture	0.019	0.981	0.000
E65-E68 Obesity and other hyperalimentation	0.000	0.981	0.019
E87.2 Acidosis	0.000	0.981	0.019
E14 Unspecified diabetes mellitus	0.000	0.982	0.018
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.982	0.018
E45 Retarded development following protein-energy malnutrition	0.000	0.982	0.018
E43 Unspecified severe protein-energy malnutrition	0.000	0.982	0.018
E42 Marasmic kwashiorkor	0.000	0.982	0.018
E41 Nutritional marasmus	0.000	0.982	0.018
E40 Kwashiorkor	0.000	0.982	0.018
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.018	0.982	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.983	0.017
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.983	0.017
E16.4 Abnormal secretion of gastrin	0.000	0.983	0.017
E16.3 Increased secretion of glucagon	0.000	0.983	0.017
E16.1 Other hypoglycaemia	0.000	0.983	0.017
E14.3 With ophthalmic complications	0.000	0.984	0.016
G45 Transient cerebral ischaemic attacks and related syndromes	0.016	0.984	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.015	0.985	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.015	0.985	0.000
E14.2 Withrenal complications	0.000	0.986	0.014
E46 Unspecified protein-energy malnutrition	0.000	0.986	0.014
E65 Localised adiposity	0.000	0.986	0.014
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.014	0.986	0.000
M80 Osteoporosis with pathological fracture	0.014	0.986	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.014	0.986	0.000
G40.9 Epilepsy, unspecified	0.014	0.986	0.000
E14.6 With other specified complications	0.000	0.986	0.014
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.014	0.986	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.014	0.986	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.014	0.986	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.014	0.986	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.014	0.986	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.014	0.986	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.014	0.986	0.000
E67 Other hyperalimentation	0.000	0.986	0.014
E68 Sequelae of hyperalimentation	0.000	0.986	0.014
G56.2 Lesion of ulnar nerve	0.014	0.986	0.000
E14.7 With multiple complications	0.000	0.986	0.013
E14.0 With coma	0.000	0.986	0.013
G43.9 Migraine, unspecified	0.013	0.987	0.000
E14.4 With neurological complications	0.000	0.987	0.013
E44.1 Mild protein-energy malnutrition	0.000	0.987	0.013
E44.0 Moderate protein-energy malnutrition	0.000	0.987	0.013
G56.8 Other mononeuropathies of upper limb	0.013	0.987	0.000
E14.5 With peripheral circulatory complications	0.000	0.987	0.013
E83.1 Disorders of iron metabolism	0.000	0.987	0.013
E14.8 With unspecified complications	0.000	0.987	0.013
G43 Migraine	0.013	0.987	0.000
M35.0 Sicca syndrome [Sjogren]	0.013	0.987	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.013	0.987	0.000
M07.3 Other psoriatic arthropathies	0.012	0.988	0.000
G56.3 Lesion of radial nerve	0.012	0.988	0.000
Q60.0 Renal agenesis, unilateral	0.012	0.988	0.000
G40-G47 Episodic and paroxysmal disorders	0.012	0.988	0.000
G45.0 Vertebro-basilar artery syndrome	0.012	0.988	0.000
G56 Mononeuropathies of upper limb	0.012	0.988	0.000
G40 Epilepsy	0.012	0.988	0.000
G43.8 Other migraine	0.011	0.989	0.000
G45.2 Multiple and bilateral precerebral artery syndromes	0.011	0.989	0.000
C44.5 Skin of trunk	0.011	0.989	0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.011	0.989	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.011	0.989	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.011	0.989	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.011	0.989	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.010	0.989	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.010	0.989	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.010	0.989	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.010	0.989	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.010	0.989	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.010	0.989	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.010	0.989	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.010	0.989	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.010	0.989	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.010	0.990	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.010	0.990	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.010	0.990	0.000
E50-E64 Other nutritional deficiencies	0.000	0.990	0.010
M80.8 Other osteoporosis with pathological fracture	0.010	0.990	0.000
E67.8 Other specified hyperalimentation	0.000	0.990	0.010
E67.3 Hypervitaminosis D	0.000	0.990	0.010
E67.2 Megavitamin-B6 syndrome	0.000	0.990	0.010
E67.1 Hypercarotenaemia	0.000	0.990	0.010
E67.0 Hypervitaminosis A	0.000	0.990	0.010
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.990	0.010
G45.1 Carotid artery syndrome (hemispheric)	0.010	0.990	0.000
E14.1 With ketoacidosis	0.000	0.990	0.009
M07.31 Other psoriatic arthropathies (Shoulder region)	0.009	0.990	0.000
G45.4 Transient global amnesia	0.010	0.990	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.009	0.990	0.000
G43.2 Status migrainosus	0.009	0.991	0.000
G56.1 Other lesions of median nerve	0.009	0.991	0.000
M06.3 Rheumatoid nodule	0.009	0.991	0.000
M07.38 Other psoriatic arthropathies (Other)	0.009	0.991	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.009	0.991	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.009	0.991	0.000
H90.5 Sensorineural hearing loss, unspecified	0.000	0.991	0.009
M06.34 Rheumatoid nodule (Hand)	0.009	0.991	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.009	0.991	0.000
H90 Conductive and sensorineural hearing loss	0.000	0.991	0.009
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.009	0.991	0.000
G43.0 Migraine without aura [common migraine]	0.009	0.991	0.000
M06 Other rheumatoid arthritis	0.009	0.991	0.000
H90.0 Conductive hearing loss, bilateral	0.000	0.991	0.009
M07 Psoriatic and enteropathic arthropathies	0.009	0.991	0.000
G44 Other headache syndromes	0.009	0.991	0.000
G43.3 Complicated migraine	0.008	0.991	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.008	0.991	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.009	0.991	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.009	0.991	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.009	0.991	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.008	0.992	0.000
H90.2 Conductive hearing loss, unspecified	0.000	0.992	0.008
M06.0 Seronegative rheumatoid arthritis	0.008	0.992	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.008	0.992	0.000
G45.3 Amaurosis fugax	0.008	0.992	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.008	0.992	0.000
M06.9 Rheumatoid arthritis, unspecified	0.008	0.992	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.992	0.008
G40.8 Other epilepsy	0.008	0.992	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.992	0.008
E56 Other vitamin deficiencies	0.000	0.992	0.008
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.008	0.992	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.008	0.992	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.008	0.992	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.008	0.992	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.008	0.992	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.008	0.992	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.008	0.992	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.008	0.992	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.008	0.992	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.008	0.992	0.000
G44.0 Cluster headache syndrome	0.008	0.992	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.008	0.992	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.008	0.992	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.008	0.992	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.008	0.992	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.008	0.992	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.008	0.992	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.008	0.992	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.008	0.992	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.008	0.992	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.008	0.992	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.008	0.992	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.008	0.992	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.008	0.992	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.008	0.992	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.008	0.992	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.008	0.992	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.008	0.992	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.008	0.992	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.008	0.992	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.008	0.992	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.008	0.992	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.008	0.992	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.008	0.992	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.008	0.992	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.008	0.992	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.008	0.992	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.008	0.992	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.008	0.992	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.008	0.992	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.008	0.992	0.000
G56.4 Causalgia	0.008	0.992	0.000
G43.1 Migraine with aura [classical migraine]	0.008	0.992	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.992	0.007
E50 Vitamin A deficiency	0.000	0.992	0.007
E60 Dietary zinc deficiency	0.000	0.992	0.007
E59 Dietary selenium deficiency	0.000	0.992	0.007
E54 Ascorbic acid deficiency	0.000	0.992	0.007
E52 Niacin deficiency [pellagra]	0.000	0.992	0.007
M06.36 Rheumatoid nodule (Lower leg)	0.008	0.992	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.007	0.992	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.007	0.992	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.007	0.992	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.007	0.992	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.007	0.992	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.007	0.992	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.007	0.992	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.007	0.992	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.007	0.992	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.008	0.992	0.000
H90.3 Sensorineural hearing loss, bilateral	0.000	0.993	0.007
E63 Other nutritional deficiencies	0.000	0.993	0.007
G56.9 Mononeuropathy of upper limb, unspecified	0.007	0.993	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.007	0.993	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.007	0.993	0.000
S82.20 Fracture of shaft of tibia (closed)	0.007	0.993	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.007	0.993	0.000
E58 Dietary calcium deficiency	0.000	0.993	0.007
G41 Status epilepticus	0.007	0.993	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.007	0.993	0.000
G44.1 Vascular headache, not elsewhere classified	0.007	0.993	0.000
M06.8 Other specified rheumatoid arthritis	0.007	0.993	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.007	0.993	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.007	0.993	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.007	0.993	0.000
M06.38 Rheumatoid nodule (Other)	0.007	0.993	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.007	0.993	0.000
M06.33 Rheumatoid nodule (Forearm)	0.007	0.993	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.007	0.993	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.007	0.993	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.993	0.007
M06.30 Rheumatoid nodule (Multiple sites)	0.007	0.993	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.007	0.993	0.000
Q60.2 Renal agenesis, unspecified	0.007	0.993	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.993	0.007
E51 Thiamine deficiency	0.000	0.993	0.006
G44.8 Other specified headache syndromes	0.007	0.993	0.000
M06.2 Rheumatoid bursitis	0.007	0.993	0.000
M06.1 Adult-onset Still's disease	0.007	0.993	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.007	0.993	0.000
M07.6 Other enteropathic arthropathies	0.006	0.993	0.000
M07.5 Arthropathy in ulcerative colitis	0.006	0.993	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.006	0.993	0.000
M07.2 Psoriatic spondylitis	0.006	0.993	0.000
M07.1 Arthritis mutilans	0.006	0.993	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.006	0.993	0.000
I34.1 Mitral (valve) prolapse	0.000	0.993	0.007
G40.7 Petit mal, unspecified, without grand mal seizures	0.006	0.993	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.006	0.994	0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases	0.006	0.994	0.000
G46.6 Pure sensory lacunar syndrome	0.006	0.994	0.000
G46.5 Pure motor lacunar syndrome	0.006	0.994	0.000
G46.4 Cerebellar stroke syndrome	0.006	0.994	0.000
G46.3 Brain stem stroke syndrome	0.006	0.994	0.000
G46.2 Posterior cerebral artery syndrome	0.006	0.994	0.000
G46.1 Anterior cerebral artery syndrome	0.006	0.994	0.000
G46.0 Middle cerebral artery syndrome	0.006	0.994	0.000
Q60.6 Potter's syndrome	0.006	0.994	0.000
Q60.5 Renal hypoplasia, unspecified	0.006	0.994	0.000
Q60.4 Renal hypoplasia, bilateral	0.006	0.994	0.000
Q60.3 Renal hypoplasia, unilateral	0.006	0.994	0.000
Q60.1 Renal agenesis, bilateral	0.006	0.994	0.000
G40.5 Special epileptic syndromes	0.006	0.994	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.006	0.994	0.000
E56.1 Deficiency of vitamin K	0.000	0.994	0.006
R21 Rash and other nonspecific skin eruption	0.000	0.994	0.006
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.006	0.994	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.006	0.994	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.006	0.994	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.006	0.994	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.006	0.994	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.006	0.994	0.000
E04.2 Non-toxic multinodular goitre	0.006	0.994	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.006	0.994	0.000
G44.3 Chronic posttraumatic headache	0.006	0.994	0.000
M05-M14 Inflammatory polyarthropathies	0.006	0.994	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.006	0.994	0.000
G46.7 Other lacunar syndromes	0.006	0.994	0.000
Z87.0 Personal history of diseases of the respiratory system	0.000	0.994	0.006
E56.9 Vitamin deficiency, unspecified	0.000	0.994	0.006
E56.8 Deficiency of other vitamins	0.000	0.994	0.006
E56.0 Deficiency of vitamin E	0.000	0.994	0.006
Q23 Congenital malformations of aortic and mitral valves	0.006	0.994	0.000
K31.1 Adult hypertrophic pyloric stenosis	0.006	0.994	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.006	0.994	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.006	0.994	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.006	0.994	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.006	0.994	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.006	0.994	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.006	0.994	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.006	0.994	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.006	0.994	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.006	0.994	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.006	0.994	0.000
E61 Deficiency of other nutrient elements	0.000	0.994	0.006
E50.9 Vitamin A deficiency, unspecified	0.000	0.994	0.006
E50.8 Other manifestations of vitamin A deficiency	0.000	0.994	0.006
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.994	0.006
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.994	0.006
E50.5 Vitamin A deficiency with night blindness	0.000	0.994	0.006
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.994	0.006
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.994	0.006
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.994	0.006
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.994	0.006
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.994	0.006
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.994	0.006
E64.8 Sequelae of other nutritional deficiencies	0.000	0.994	0.006
E64.3 Sequelae of rickets	0.000	0.994	0.006
E64.2 Sequelae of vitamin C deficiency	0.000	0.994	0.006
E64.1 Sequelae of vitamin A deficiency	0.000	0.994	0.006
E64.0 Sequelae of protein-energy malnutrition	0.000	0.994	0.006
M06.32 Rheumatoid nodule (Upper arm)	0.006	0.994	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.006	0.994	0.000
Q25 Congenital malformations of great arteries	0.006	0.994	0.000
G41.8 Other status epilepticus	0.006	0.994	0.000
Q23.1 Congenital insufficiency of aortic valve	0.006	0.994	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.005	0.994	0.000
H21.8 Other specified disorders of iris and ciliary body	0.000	0.994	0.006
E55 Vitamin D deficiency	0.000	0.994	0.006
E63.8 Other specified nutritional deficiencies	0.000	0.994	0.005
E63.1 Imbalance of constituents of food intake	0.000	0.994	0.005
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.994	0.005
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.006	0.994	0.000
Q60-Q64 Congenital malformations of the urinary system	0.006	0.994	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.005	0.995	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.005	0.995	0.000
Q24 Other congenital malformations of heart	0.005	0.995	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.000	0.995	0.005
Q50-Q56 Congenital malformations of genital organs	0.005	0.995	0.000
G41.1 Petit mal status epilepticus	0.005	0.995	0.000
E63.9 Nutritional deficiency, unspecified	0.000	0.995	0.005
E53 Deficiency of other B group vitamins	0.000	0.995	0.005
M06.88 Other specified rheumatoid arthritis (Other)	0.005	0.995	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.005	0.995	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.005	0.995	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.005	0.995	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.005	0.995	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.005	0.995	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.005	0.995	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.005	0.995	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.005	0.995	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.995	0.005
Q24.9 Congenital malformation of the heart, unspecified	0.005	0.995	0.000
G41.0 Grand mal status epilepticus	0.005	0.995	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.995	0.005
Q26 Congenital malformations of great veins	0.005	0.995	0.000
G41.2 Complex partial status epilepticus	0.005	0.995	0.000
Q25.0 Patent ductus arteriosus	0.005	0.995	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.005	0.995	0.000
Q74 Other congenital malformations of limb(s)	0.005	0.995	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.005	0.995	0.000
E51.9 Thiamine deficiency, unspecified	0.000	0.995	0.005
E51.8 Other manifestations of thiamine deficiency	0.000	0.995	0.005
E51.1 Beriberi	0.000	0.995	0.005
M06.19 Adult-onset Still's disease (Site unspecified)	0.005	0.995	0.000
M06.18 Adult-onset Still's disease (Other)	0.005	0.995	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.005	0.995	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.005	0.995	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations