TreeWAS – Variant ID: rs12045440

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E04.2 Non-toxic multinodular goitre	0.000	0.001	0.999
E04 Other non-toxic goitre	0.000	0.002	0.998
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.005	0.995
E00-E07 Disorders of thyroid gland	0.000	0.006	0.994
E05.9 Thyrotoxicosis, unspecified	0.000	0.007	0.993
E04.1 Non-toxic single thyroid nodule	0.000	0.015	0.985
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.075	0.925
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.099	0.901
E05.8 Other thyrotoxicosis	0.000	0.134	0.866
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.208	0.792
E04.8 Other specified non-toxic goitre	0.000	0.284	0.716
E05.5 Thyroid crisis or storm	0.000	0.286	0.713
E05.4 Thyrotoxicosis factitia	0.000	0.286	0.713
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.286	0.713
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.287	0.713
E00 Congenital iodine-deficiency syndrome	0.000	0.287	0.713
E04.0 Non-toxic diffuse goitre	0.000	0.360	0.640
E06 Thyroiditis	0.000	0.394	0.606
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.396	0.604
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.489	0.511
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.489	0.511
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.489	0.511
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.489	0.511
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.489	0.511
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.489	0.511
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.489	0.511
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.489	0.511
E07 Other disorders of thyroid	0.000	0.518	0.482
E03 Other hypothyroidism	0.001	0.561	0.437
E06.5 Other chronic thyroiditis	0.000	0.565	0.435
E06.4 Drug-induced thyroiditis	0.000	0.565	0.435
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.565	0.435
E06.1 Subacute thyroiditis	0.000	0.565	0.435
E06.0 Acute thyroiditis	0.000	0.565	0.435
E04.9 Non-toxic goitre, unspecified	0.000	0.568	0.432
E06.3 Autoimmune thyroiditis	0.000	0.596	0.404
E06.9 Thyroiditis, unspecified	0.000	0.630	0.370
E07.1 Dyshormogenetic goitre	0.000	0.654	0.346
E07.0 Hypersecretion of calcitonin	0.000	0.654	0.346
E03.8 Other specified hypothyroidism	0.001	0.660	0.339
E03.1 Congenital hypothyroidism without goitre	0.001	0.665	0.334
E03.5 Myxoedema coma	0.001	0.685	0.314
E03.4 Atrophy of thyroid (acquired)	0.001	0.685	0.314
E03.3 Postinfectious hypothyroidism	0.001	0.685	0.314
E03.0 Congenital hypothyroidism with diffuse goitre	0.001	0.685	0.314
E07.8 Other specified disorders of thyroid	0.000	0.717	0.283
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.001	0.732	0.267
E07.9 Disorder of thyroid, unspecified	0.000	0.770	0.230
M13.96 Arthritis, unspecified (Lower leg)	0.000	0.980	0.020
H20.9 Iridocyclitis, unspecified	0.000	0.987	0.013
E89.0 Postprocedural hypothyroidism	0.000	0.988	0.012
D23.5 Skin of trunk	0.000	0.989	0.011
M20.5 Other deformities of toe(s) (acquired)	0.011	0.989	0.000
B35.3 Tinea pedis	0.009	0.991	0.000
H60.9 Otitis externa, unspecified	0.009	0.991	0.000
J32.9 Chronic sinusitis, unspecified	0.009	0.991	0.000
Z34.0 Supervision of normal first pregnancy	0.000	0.991	0.009
N30.3 Trigonitis	0.009	0.991	0.000
B35.1 Tinea unguium	0.008	0.992	0.000
J02.9 Acute pharyngitis, unspecified	0.008	0.992	0.000
B35 Dermatophytosis	0.008	0.992	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.000	0.992	0.008
H43.3 Other vitreous opacities	0.008	0.992	0.000
H20 Iridocyclitis	0.000	0.992	0.008
I84.3 External thrombosed haemorrhoids	0.000	0.993	0.007
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.993	0.007
E89.2 Postprocedural hypoparathyroidism	0.000	0.993	0.007
B35.9 Dermatophytosis, unspecified	0.007	0.993	0.000
H20.0 Acute and subacute iridocyclitis	0.000	0.994	0.006
B35.4 Tinea corporis	0.006	0.994	0.000
R82 Other abnormal findings in urine	0.000	0.994	0.006
R82.8 Abnormal findings on cytological and histological examination of urine	0.000	0.994	0.006
H92.1 Otorrhoea	0.006	0.994	0.000
E89.3 Postprocedural hypopituitarism	0.000	0.994	0.006
H20.8 Other iridocyclitis	0.000	0.994	0.006
R81 Glycosuria	0.000	0.994	0.006
B35.8 Other dermatophytoses	0.006	0.994	0.000
B35.5 Tinea imbricata	0.006	0.994	0.000
B35.2 Tinea manuum	0.006	0.994	0.000
B35.0 Tinea barbae and tinea capitis	0.006	0.994	0.000
H92 Otalgia and effusion of ear	0.006	0.994	0.000
H20.2 Lens-induced iridocyclitis	0.000	0.994	0.006
H60.8 Other otitis externa	0.006	0.994	0.000
E03.9 Hypothyroidism, unspecified	0.006	0.994	0.000
H20.1 Chronic iridocyclitis	0.000	0.994	0.006
H60 Otitis externa	0.006	0.994	0.000
R82.9 Other and unspecified abnormal finding in urine	0.000	0.995	0.005
R82.1 Myoglobinuria	0.000	0.995	0.005
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.995	0.005
E89.5 Postprocedural testicular hypofunction	0.000	0.995	0.005
H92.0 Otalgia	0.005	0.995	0.000
R82.4 Acetonuria	0.000	0.995	0.005
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.000	0.995	0.005
Z93.1 Gastrostomy status	0.005	0.995	0.000
E89.1 Postprocedural hypoinsulinaemia	0.000	0.995	0.005
B35.6 Tinea cruris	0.005	0.995	0.000
R82.7 Abnormal findings on microbiological examination of urine	0.000	0.995	0.005
H92.2 Otorrhagia	0.005	0.995	0.000
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.000	0.995	0.005
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.000	0.995	0.005
R82.3 Haemoglobinuria	0.000	0.995	0.005
R82.2 Biliuria	0.000	0.995	0.005
R82.0 Chyluria	0.000	0.995	0.005
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.995	0.005
H90-H95 Other disorders of ear	0.005	0.995	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.005	0.995	0.000
H65-H75 Diseases of middle ear and mastoid	0.005	0.995	0.000
H72 Perforation of tympanic membrane	0.005	0.995	0.000
H66 Suppurative and unspecified otitis media	0.005	0.995	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.004	0.995	0.000
E89.4 Postprocedural ovarian failure	0.000	0.996	0.004
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.996	0.004
Y57.5 X-ray contrast media	0.000	0.996	0.004
H60-H62 Diseases of external ear	0.004	0.996	0.000
H71 Cholesteatoma of middle ear	0.004	0.996	0.000
J02 Acute pharyngitis	0.004	0.996	0.000
H60.2 Malignant otitis externa	0.004	0.996	0.000
H93 Other disorders of ear, not elsewhere classified	0.004	0.996	0.000
Chapter VIII Diseases of the ear and mastoid process	0.004	0.996	0.000
H60.4 Cholesteatoma of external ear	0.004	0.996	0.000
H60.5 Acute otitis externa, non-infective	0.004	0.996	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.004	0.996	0.000
L29.2 Pruritus vulvae	0.000	0.996	0.004
H66.1 Chronic tubotympanic suppurative otitis media	0.004	0.996	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.004	0.996	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.004	0.996	0.000
H66.9 Otitis media, unspecified	0.004	0.996	0.000
H72.8 Other perforations of tympanic membrane	0.004	0.996	0.000
H70 Mastoiditis and related conditions	0.004	0.996	0.000
H95.1 Other disorders following mastoidectomy	0.004	0.996	0.000
I49.3 Ventricular premature depolarisation	0.000	0.996	0.004
D35.1 Parathyroid gland	0.004	0.996	0.000
R80 Isolated proteinuria	0.000	0.996	0.004
H60.0 Abscess of external ear	0.004	0.996	0.000
H93.8 Other specified disorders of ear	0.004	0.996	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.004	0.996	0.000
H66.0 Acute suppurative otitis media	0.004	0.996	0.000
H72.1 Attic perforation of tympanic membrane	0.004	0.996	0.000
H93.3 Disorders of acoustic nerve	0.004	0.996	0.000
H93.2 Other abnormal auditory perceptions	0.004	0.996	0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.000	0.996	0.004
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.003	0.996	0.000
H68 Eustachian salpingitis and obstruction	0.003	0.996	0.000
H67 Otitis media in diseases classified elsewhere	0.003	0.996	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.004	0.996	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.003	0.996	0.000
H72.0 Central perforation of tympanic membrane	0.003	0.996	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.003	0.996	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.003	0.996	0.000
H70.8 Other mastoiditis and related conditions	0.003	0.997	0.000
H60.1 Cellulitis of external ear	0.003	0.997	0.000
D47.1 Chronic myeloproliferative disease	0.000	0.997	0.003
H66.4 Suppurative otitis media, unspecified	0.003	0.997	0.000
F43.0 Acute stress reaction	0.003	0.997	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.997	0.003
H93.9 Disorder of ear, unspecified	0.003	0.997	0.000
H66.3 Other chronic suppurative otitis media	0.003	0.997	0.000
H93.0 Degenerative and vascular disorders of ear	0.003	0.997	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.003	0.997	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.003	0.997	0.000
H74 Other disorders of middle ear and mastoid	0.003	0.997	0.000
H70.1 Chronic mastoiditis	0.003	0.997	0.000
L29.8 Other pruritus	0.000	0.997	0.003
H69 Other disorders of Eustachian tube	0.003	0.997	0.000
H70.2 Petrositis	0.003	0.997	0.000
H70.0 Acute mastoiditis	0.003	0.997	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.003	0.997	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.003	0.997	0.000
I33.0 Acute and subacute infective endocarditis	0.003	0.997	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.003	0.997	0.000
H65 Nonsuppurative otitis media	0.003	0.997	0.000
J02.0 Streptococcal pharyngitis	0.003	0.997	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.003	0.997	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
J02.8 Acute pharyngitis due to other specified organisms	0.003	0.997	0.000
S46.3 Injury of muscle and tendon of triceps	0.003	0.997	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.003	0.997	0.000
H74.0 Tympanosclerosis	0.003	0.997	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.003	0.997	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.003	0.997	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.003	0.997	0.000
H68.1 Obstruction of Eustachian tube	0.003	0.997	0.000
H68.0 Eustachian salpingitis	0.003	0.997	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.003	0.997	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.003	0.997	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
H73 Other disorders of tympanic membrane	0.003	0.997	0.000
H65.0 Acute serous otitis media	0.003	0.997	0.000
O26.9 Pregnancy-related condition, unspecified	0.003	0.997	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.003	0.997	0.000
H70.9 Mastoiditis, unspecified	0.003	0.997	0.000
H60.3 Other infective otitis externa	0.002	0.997	0.001
E40-E46 Malnutrition	0.000	0.997	0.003
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.997	0.003
O92.1 Cracked nipple associated with childbirth	0.003	0.997	0.000
H91.8 Other specified hearing loss	0.003	0.997	0.000
D73.0 Hyposplenism	0.003	0.997	0.000
H72.2 Other marginal perforations of tympanic membrane	0.002	0.997	0.000
H91 Other hearing loss	0.003	0.997	0.000
R61.0 Localised hyperhidrosis	0.000	0.997	0.003
Y52 Agents primarily affecting the cardiovascular system	0.000	0.997	0.003
H65.2 Chronic serous otitis media	0.003	0.997	0.000
H69.9 Eustachian tube disorder, unspecified	0.002	0.997	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.002	0.997	0.000
H69.0 Patulous Eustachian tube	0.002	0.997	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.002	0.997	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.002	0.998	0.000
H74.1 Adhesive middle ear disease	0.002	0.998	0.000
H46 Optic neuritis	0.000	0.998	0.002
H62.8 Other disorders of external ear in diseases classified elsewhere	0.002	0.998	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.002	0.998	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H62.2 Otitis externa in mycoses	0.002	0.998	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.002	0.998	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.002	0.998	0.000
O85-O92 Complications predominantly related to the puerperium	0.002	0.998	0.000
O92.7 Other and unspecified disorders of lactation	0.002	0.998	0.000
O92.6 Galactorrhoea	0.002	0.998	0.000
O92.5 Suppressed lactation	0.002	0.998	0.000
O92.4 Hypogalactia	0.002	0.998	0.000
O92.3 Agalactia	0.002	0.998	0.000
O92.0 Retracted nipple associated with childbirth	0.002	0.998	0.000
L29 Pruritus	0.000	0.998	0.002
H73.1 Chronic myringitis	0.002	0.998	0.000
M93.9 Osteochondropathy, unspecified	0.000	0.998	0.002
E46 Unspecified protein-energy malnutrition	0.000	0.998	0.002
O89 Complications of anaesthesia during the puerperium	0.002	0.998	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.002	0.998	0.000
S05.1 Contusion of eyeball and orbital tissues	0.000	0.998	0.002
O85 Puerperal sepsis	0.002	0.998	0.000
H73.0 Acute myringitis	0.002	0.998	0.000
H65.1 Other acute nonsuppurative otitis media	0.002	0.998	0.000
J00-J06 Acute upper respiratory infections	0.002	0.998	0.000
H90 Conductive and sensorineural hearing loss	0.002	0.998	0.000
O90 Complications of the puerperium, not elsewhere classified	0.002	0.998	0.000
H91.0 Ototoxic hearing loss	0.002	0.998	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.998	0.002
E45 Retarded development following protein-energy malnutrition	0.000	0.998	0.002
E43 Unspecified severe protein-energy malnutrition	0.000	0.998	0.002
E42 Marasmic kwashiorkor	0.000	0.998	0.002
E41 Nutritional marasmus	0.000	0.998	0.002
E40 Kwashiorkor	0.000	0.998	0.002
J00 Acute nasopharyngitis [common cold]	0.002	0.998	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.002	0.998	0.000
K22.9 Disease of oesophagus, unspecified	0.000	0.998	0.002
R61.9 Hyperhidrosis, unspecified	0.000	0.998	0.002
J01 Acute sinusitis	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.000	0.998	0.002
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.998	0.002
H90.2 Conductive hearing loss, unspecified	0.002	0.998	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.002	0.998	0.000
T85.2 Mechanical complication of intraocular lens	0.000	0.998	0.002
M13.91 Arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.002
Y52.7 Peripheral vasodilators	0.000	0.998	0.002
J01.1 Acute frontal sinusitis	0.002	0.998	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.002
Y52.1 Calcium-channel blockers	0.000	0.998	0.002
H90.3 Sensorineural hearing loss, bilateral	0.002	0.998	0.000
H91.3 Deaf mutism, not elsewhere classified	0.002	0.998	0.000
G72.9 Myopathy, unspecified	0.000	0.998	0.002
O88 Obstetric embolism	0.002	0.998	0.000
H74.4 Polyp of middle ear	0.002	0.998	0.000
H91.2 Sudden idiopathic hearing loss	0.002	0.998	0.000
L29.3 Anogenital pruritus, unspecified	0.000	0.998	0.002
L29.1 Pruritus scroti	0.000	0.998	0.002
O90.9 Complication of the puerperium, unspecified	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
Y57.6 Other diagnostic agents	0.000	0.998	0.002
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.002	0.998	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.002	0.998	0.000
O89.6 Failed or difficult intubation during the puerperium	0.002	0.998	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.002	0.998	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.002	0.998	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.002	0.998	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.002	0.998	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.002	0.998	0.000
J01.4 Acute pansinusitis	0.002	0.998	0.000
M75.1 Rotator cuff syndrome	0.002	0.998	0.000
O91 Infections of breast associated with childbirth	0.002	0.998	0.000
H80-H83 Diseases of inner ear	0.002	0.998	0.000
H91.1 Presbycusis	0.002	0.998	0.000
J01.0 Acute maxillary sinusitis	0.002	0.998	0.000
O90.0 Disruption of Caesarean section wound	0.002	0.998	0.000
H61 Other disorders of external ear	0.002	0.998	0.000
O87 Venous complications in the puerperium	0.002	0.998	0.000
O86 Other puerperal infections	0.002	0.998	0.000
H61.8 Other specified disorders of external ear	0.002	0.998	0.000
J01.8 Other acute sinusitis	0.002	0.998	0.000
O90.5 Postpartum thyroiditis	0.002	0.998	0.000
O90.4 Postpartum acute renal failure	0.002	0.998	0.000
O90.3 Cardiomyopathy in the puerperium	0.002	0.998	0.000
O90.2 Haematoma of obstetric wound	0.002	0.998	0.000
J06.9 Acute upper respiratory infection, unspecified	0.002	0.998	0.000
E44.1 Mild protein-energy malnutrition	0.000	0.998	0.002
E44.0 Moderate protein-energy malnutrition	0.000	0.998	0.002
H61.9 Disorder of external ear, unspecified	0.002	0.998	0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.002	0.998	0.000
G71.0 Muscular dystrophy	0.000	0.998	0.002
H69.8 Other specified disorders of Eustachian tube	0.002	0.998	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.002	0.998	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
J01.9 Acute sinusitis, unspecified	0.002	0.998	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.002
R61 Hyperhidrosis	0.000	0.998	0.002
M43.09 Spondylolysis (Site unspecified)	0.002	0.998	0.000
J01.3 Acute sphenoidal sinusitis	0.002	0.998	0.000
Y57.7 Vitamins, not elsewhere classified	0.000	0.998	0.002
Y57.4 Pharmaceutical excipients	0.000	0.998	0.002
Y57.3 Alcohol deterrents	0.000	0.998	0.002
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.002
Y57.1 Lipotropic drugs	0.000	0.998	0.002
Y57.0 Appetite depressants [anorectics]	0.000	0.998	0.002
E15 Nondiabetic hypoglycaemic coma	0.000	0.998	0.002
B34.9 Viral infection, unspecified	0.002	0.998	0.000
H90.0 Conductive hearing loss, bilateral	0.002	0.998	0.000
J06.0 Acute laryngopharyngitis	0.002	0.998	0.000
J32.2 Chronic ethmoidal sinusitis	0.002	0.998	0.000
O87.2 Haemorrhoids in the puerperium	0.002	0.998	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.002	0.998	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.002	0.998	0.000
J06.8 Other acute upper respiratory infections of multiple sites	0.002	0.998	0.000
L29.9 Pruritus, unspecified	0.000	0.998	0.002
Y57.8 Other drugs and medicaments	0.000	0.998	0.002
M43.06 Spondylolysis (Lumbar region)	0.002	0.998	0.000
D23.4 Skin of scalp and neck	0.000	0.998	0.002
O90.1 Disruption of perineal obstetric wound	0.002	0.998	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.002	0.998	0.000
O86.2 Urinary tract infection following delivery	0.002	0.998	0.000
O86.0 Infection of obstetric surgical wound	0.002	0.998	0.000
R43.8 Other and unspecified disturbances of smell and taste	0.002	0.998	0.000
I33.9 Acute endocarditis, unspecified	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.002	0.998	0.000
O88.8 Other obstetric embolism	0.001	0.998	0.000
O88.3 Obstetric pyaemic and septic embolism	0.001	0.998	0.000
O88.2 Obstetric blood-clot embolism	0.001	0.998	0.000
O88.1 Amniotic fluid embolism	0.001	0.998	0.000
O88.0 Obstetric air embolism	0.001	0.998	0.000
B17.1 Acute hepatitis C	0.002	0.998	0.000
H65.4 Other chronic nonsuppurative otitis media	0.002	0.998	0.000
O86.1 Other infection of genital tract following delivery	0.002	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.000	0.998	0.002
I33 Acute and subacute endocarditis	0.002	0.998	0.000
D23.6 Skin of upper limb, including shoulder	0.000	0.998	0.002
K86.8 Other specified diseases of pancreas	0.000	0.998	0.002
O86.8 Other specified puerperal infections	0.002	0.998	0.000
O86.3 Other genito-urinary tract infections following delivery	0.002	0.998	0.000
O91.0 Infection of nipple associated with childbirth	0.001	0.998	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.002	0.998	0.000
O87.9 Venous complication in the puerperium, unspecified	0.001	0.998	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.001	0.998	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.001	0.998	0.000
R23.3 Spontaneous ecchymoses	0.000	0.998	0.002
J01.2 Acute ethmoidal sinusitis	0.001	0.998	0.000
J05.0 Acute obstructive laryngitis [croup]	0.001	0.998	0.000
O87.8 Other venous complications in the puerperium	0.001	0.998	0.000
K86.2 Cyst of pancreas	0.000	0.998	0.002
R61.1 Generalised hyperhidrosis	0.000	0.998	0.001
H43.2 Crystalline deposits in vitreous body	0.002	0.998	0.000
H65.3 Chronic mucoid otitis media	0.002	0.998	0.000
I82.2 Embolism and thrombosis of vena cava	0.000	0.998	0.002
J05.1 Acute epiglottitis	0.001	0.998	0.000
H61.1 Non-infective disorders of pinna	0.001	0.998	0.000
J32.3 Chronic sphenoidal sinusitis	0.001	0.998	0.000
Z34 Supervision of normal pregnancy	0.000	0.998	0.002
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.998	0.000
L50.0 Allergic urticaria	0.000	0.998	0.002
R10.2 Pelvic and perineal pain	0.002	0.998	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.000	0.998	0.002
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.998	0.002
H61.3 Acquired stenosis of external ear canal	0.001	0.998	0.000
H83.3 Noise effects on inner ear	0.001	0.998	0.000
J32 Chronic sinusitis	0.002	0.998	0.000
O91.1 Abscess of breast associated with childbirth	0.001	0.998	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.001	0.998	0.000
J95.0 Tracheostomy malfunction	0.001	0.999	0.000
H83.9 Disease of inner ear, unspecified	0.001	0.999	0.000
K59.3 Megacolon, not elsewhere classified	0.000	0.999	0.001
H43 Disorders of vitreous body	0.001	0.999	0.000
H83 Other diseases of inner ear	0.001	0.999	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.001	0.999	0.000
M43.0 Spondylolysis	0.001	0.999	0.000
J04 Acute laryngitis and tracheitis	0.001	0.999	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.001	0.999	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.000	0.999	0.001
K35.8 Acute appendicitis, other and unspecified	0.001	0.999	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.001	0.999	0.000
D15.1 Heart	0.001	0.999	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.999	0.001
A49.8 Other bacterial infections of unspecified site	0.001	0.999	0.000
H81.4 Vertigo of central origin	0.001	0.999	0.000
B17.9 Acute viral hepatitis, unspecified	0.001	0.999	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.999	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.999	0.001
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.001	0.999	0.000
H43.0 Vitreous prolapse	0.001	0.999	0.000
H83.2 Labyrinthine dysfunction	0.001	0.999	0.000
H93.1 Tinnitus	0.001	0.999	0.000
C79.6 Secondary malignant neoplasm of ovary	0.001	0.999	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.999	0.001
J03 Acute tonsillitis	0.001	0.999	0.000
D09.0 Bladder	0.000	0.999	0.001
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M43.07 Spondylolysis (Lumbosacral region)	0.001	0.999	0.000
M43.05 Spondylolysis (Thoracolumbar region)	0.001	0.999	0.000
M43.04 Spondylolysis (Thoracic region)	0.001	0.999	0.000
M43.03 Spondylolysis (Cervicothoracic region)	0.001	0.999	0.000
M43.01 Spondylolysis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M43.00 Spondylolysis (Multiple sites in spine)	0.001	0.999	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.000	0.999	0.001
D73.4 Cyst of spleen	0.001	0.999	0.000
H83.1 Labyrinthine fistula	0.001	0.999	0.000
J04.2 Acute laryngotracheitis	0.001	0.999	0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.001	0.999	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.000	0.999	0.001
B17 Other acute viral hepatitis	0.001	0.999	0.000
G71 Primary disorders of muscles	0.000	0.999	0.001
M93 Other osteochondropathies	0.000	0.999	0.001
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.001	0.999	0.000
O86.4 Pyrexia of unknown origin following delivery	0.001	0.999	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.999	0.001
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.999	0.001
H81.8 Other disorders of vestibular function	0.001	0.999	0.000
H81.2 Vestibular neuronitis	0.001	0.999	0.000
K26.7 Chronic without haemorrhage or perforation	0.000	0.999	0.001
S14.1 Other and unspecified injuries of cervical spinal cord	0.000	0.999	0.001
S92.00 Fracture of calcaneus (closed)	0.000	0.999	0.001
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.999	0.001
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.999	0.001
E16.4 Abnormal secretion of gastrin	0.000	0.999	0.001
E16.3 Increased secretion of glucagon	0.000	0.999	0.001
E16.1 Other hypoglycaemia	0.000	0.999	0.001
H83.8 Other specified diseases of inner ear	0.001	0.999	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.999	0.001
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
Z51.9 Medical care, unspecified	0.000	0.999	0.001
C18.4 Transverse colon	0.000	0.999	0.001
H81.3 Other peripheral vertigo	0.001	0.999	0.000
K65.0 Acute peritonitis	0.000	0.999	0.001
N50.8 Other specified disorders of male genital organs	0.001	0.999	0.000
Q43.0 Meckel's diverticulum	0.000	0.999	0.001
B17.8 Other specified acute viral hepatitis	0.001	0.999	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.999	0.001
J03.8 Acute tonsillitis due to other specified organisms	0.001	0.999	0.000
J03.0 Streptococcal tonsillitis	0.001	0.999	0.000
O47.0 False labour before 37 completed weeks of gestation	0.001	0.999	0.000
Q43.3 Congenital malformations of intestinal fixation	0.000	0.999	0.001
M65.84 Other synovitis and tenosynovitis (Hand)	0.000	0.999	0.001
B17.2 Acute hepatitis E	0.001	0.999	0.000
B17.0 Acute delta-(super) infection of hepatitis B carrier	0.001	0.999	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.999	0.001
G71.9 Primary disorder of muscle, unspecified	0.000	0.999	0.001
G71.8 Other primary disorders of muscles	0.000	0.999	0.001
G71.2 Congenital myopathies	0.000	0.999	0.001
I86.8 Varicose veins of other specified sites	0.001	0.999	0.000
M93.8 Other specified osteochondropathies	0.000	0.999	0.001
M93.2 Osteochondritis dissecans	0.000	0.999	0.001
M93.1 Kienbock's disease of adults	0.000	0.999	0.001
M93.0 Slipped upper femoral epiphysis (nontraumatic)	0.000	0.999	0.001
H81 Disorders of vestibular function	0.001	0.999	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.001	0.999	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.001	0.999	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.000	0.999	0.001
E79 Disorders of purine and pyrimidine metabolism	0.000	0.999	0.001
D14.1 Larynx	0.001	0.999	0.000
K75.4 Autoimmune hepatitis	0.001	0.999	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.999	0.001
R41.2 Retrograde amnesia	0.001	0.999	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.000	0.999	0.001
E74 Other disorders of carbohydrate metabolism	0.000	0.999	0.001
H80 Otosclerosis	0.001	0.999	0.000
M93.26 Osteochondritis dissecans knee	0.000	0.999	0.001
M93.86 Other specified osteochondropathies, lower leg	0.000	0.999	0.001
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.001	0.999	0.000
B47.9 Mycetoma, unspecified	0.001	0.999	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.000	0.999	0.001
R43.2 Parageusia	0.001	0.999	0.000
X41.9 Unspecified place	0.001	0.999	0.000
Z93.3 Colostomy status	0.000	0.999	0.001
B34 Viral infection of unspecified site	0.001	0.999	0.000
M40.24 Other and unspecified kyphosis (Thoracic region)	0.000	0.999	0.001
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.001	0.999	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.999	0.001
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.999	0.001
E79.1 Lesch-Nyhan syndrome	0.000	0.999	0.001
H90.5 Sensorineural hearing loss, unspecified	0.001	0.999	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.999	0.001
E34.9 Endocrine disorder, unspecified	0.001	0.999	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.999	0.001
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.999	0.001
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.999	0.001
E74.2 Disorders of galactose metabolism	0.000	0.999	0.001
E74.1 Disorders of fructose metabolism	0.000	0.999	0.001
E74.0 Glycogen storage disease	0.000	0.999	0.001
E70-E90 Metabolic disorders	0.000	0.999	0.001
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations