TreeWAS – Variant ID: rs12059546

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C67.9 Bladder, unspecified	0.000	0.873	0.127
C67 Malignant neoplasm of bladder	0.000	0.909	0.091
C67.2 Lateral wall of bladder	0.000	0.918	0.082
C67.6 Ureteric orifice	0.000	0.921	0.079
C67.5 Bladder neck	0.000	0.926	0.074
D12.5 Sigmoid colon	0.000	0.929	0.071
C67.0 Trigone of bladder	0.000	0.931	0.069
C67.7 Urachus	0.000	0.934	0.065
C67.4 Posterior wall of bladder	0.000	0.935	0.065
C67.8 Overlapping lesion of bladder	0.000	0.940	0.060
C67.1 Dome of bladder	0.000	0.944	0.056
C67.3 Anterior wall of bladder	0.000	0.956	0.043
C50.4 Upper-outer quadrant of breast	0.000	0.979	0.021
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.980	0.020
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.981	0.019
S06 Intracranial injury	0.000	0.981	0.019
S06.0 Concussion	0.000	0.982	0.018
S06.8 Other intracranial injuries	0.000	0.983	0.017
S06.5 Traumatic subdural haemorrhage	0.000	0.983	0.017
S06.00 Concussion (without open intracranial wound)	0.000	0.983	0.017
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.983	0.017
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.984	0.016
S06.2 Diffuse brain injury	0.000	0.985	0.015
S06.3 Focal brain injury	0.000	0.986	0.014
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.986	0.014
S06.7 Intracranial injury with prolonged coma	0.000	0.986	0.014
S06.1 Traumatic cerebral oedema	0.000	0.986	0.014
S06.9 Intracranial injury, unspecified	0.000	0.987	0.013
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.987	0.013
S06.01 Concussion (with open intracranial wound)	0.000	0.987	0.013
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.987	0.013
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.987	0.013
S06.4 Epidural haemorrhage	0.000	0.988	0.012
B02.9 Zoster without complication	0.012	0.988	0.000
C64-C68 Malignant neoplasms of urinary tract	0.000	0.988	0.012
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.989	0.011
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.989	0.011
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.990	0.010
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.990	0.010
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.990	0.010
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.990	0.010
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.990	0.010
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.990	0.010
Q18.0 Sinus, fistula and cyst of branchial cleft	0.009	0.990	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.991	0.009
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.991	0.009
B02 Zoster [herpes zoster]	0.009	0.991	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.000	0.991	0.009
Q18 Other congenital malformations of face and neck	0.008	0.992	0.000
Z85.5 Personal history of malignant neoplasm of urinary tract	0.000	0.992	0.008
M95.0 Acquired deformity of nose	0.000	0.992	0.008
B02.2 Zoster with other nervous system involvement	0.007	0.992	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.993	0.007
C66 Malignant neoplasm of ureter	0.000	0.993	0.007
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.007	0.993	0.000
K74.3 Primary biliary cirrhosis	0.000	0.993	0.007
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.007	0.993	0.000
C65 Malignant neoplasm of renal pelvis	0.000	0.993	0.007
C68.0 Urethra	0.000	0.993	0.007
Q18.1 Preauricular sinus and cyst	0.007	0.993	0.000
B02.8 Zoster with other complications	0.006	0.993	0.000
B02.7 Disseminated zoster	0.006	0.993	0.000
B02.1 Zoster meningitis	0.006	0.993	0.000
B02.0 Zoster encephalitis	0.006	0.993	0.000
C68.9 Urinary organ, unspecified	0.000	0.993	0.006
C68.8 Overlapping lesion of urinary organs	0.000	0.993	0.006
C68.1 Paraurethral glands	0.000	0.993	0.006
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.000	0.994	0.006
Q18.9 Congenital malformation of face and neck, unspecified	0.006	0.994	0.000
Q18.8 Other specified congenital malformations of face and neck	0.006	0.994	0.000
Q18.7 Microcheilia	0.006	0.994	0.000
Q18.6 Macrocheilia	0.006	0.994	0.000
Q18.5 Microstomia	0.006	0.994	0.000
Q18.4 Macrostomia	0.006	0.994	0.000
Q18.3 Webbing of neck	0.006	0.994	0.000
Q18.2 Other branchial cleft malformations	0.006	0.994	0.000
Q14 Congenital malformations of posterior segment of eye	0.006	0.994	0.000
B02.3 Zoster ocular disease	0.006	0.994	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.006	0.994	0.000
Q14.1 Congenital malformation of retina	0.005	0.994	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.995	0.005
Q12 Congenital lens malformations	0.005	0.995	0.000
Q17 Other congenital malformations of ear	0.005	0.995	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.005	0.995	0.000
Q15 Other congenital malformations of eye	0.005	0.995	0.000
Q13 Congenital malformations of anterior segment of eye	0.005	0.995	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.005	0.995	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.005	0.995	0.000
D73.0 Hyposplenism	0.005	0.995	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.005	0.995	0.000
Q66 Congenital deformities of feet	0.005	0.995	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.005	0.995	0.000
D72.8 Other specified disorders of white blood cells	0.005	0.995	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.005	0.995	0.000
H43.3 Other vitreous opacities	0.005	0.995	0.000
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.004	0.995	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.004	0.995	0.000
Q14.3 Congenital malformation of choroid	0.004	0.995	0.000
Q14.2 Congenital malformation of optic disk	0.004	0.995	0.000
Q14.0 Congenital malformation of vitreous humour	0.004	0.995	0.000
Q10.0 Congenital ptosis	0.004	0.995	0.000
B00 Herpesviral [herpes simplex] infections	0.005	0.995	0.000
Q66.3 Other congenital varus deformities of feet	0.004	0.996	0.000
B07 Viral warts	0.004	0.996	0.000
R42 Dizziness and giddiness	0.000	0.996	0.004
B00.1 Herpesviral vesicular dermatitis	0.004	0.996	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.004	0.996	0.000
Q00-Q07 Congenital malformations of the nervous system	0.004	0.996	0.000
Q66.6 Other congenital valgus deformities of feet	0.004	0.996	0.000
Q76 Congenital malformations of spine and bony thorax	0.004	0.996	0.000
Q10.7 Congenital malformation of orbit	0.004	0.996	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.004	0.996	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.004	0.996	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.004	0.996	0.000
Q10.3 Other congenital malformations of eyelid	0.004	0.996	0.000
Q10.2 Congenital entropion	0.004	0.996	0.000
Q10.1 Congenital ectropion	0.004	0.996	0.000
B01 Varicella [chickenpox]	0.004	0.996	0.000
Q12.0 Congenital cataract	0.004	0.996	0.000
Q67.5 Congenital deformity of spine	0.004	0.996	0.000
Q12.9 Congenital lens malformation, unspecified	0.004	0.996	0.000
Q12.8 Other congenital lens malformations	0.004	0.996	0.000
Q12.4 Spherophakia	0.004	0.996	0.000
Q12.3 Congenital aphakia	0.004	0.996	0.000
Q12.2 Coloboma of lens	0.004	0.996	0.000
Q12.1 Congenital displaced lens	0.004	0.996	0.000
Q05 Spina bifida	0.004	0.996	0.000
Q17.5 Prominent ear	0.004	0.996	0.000
Q78 Other osteochondrodysplasias	0.004	0.996	0.000
Q17.9 Congenital malformation of ear, unspecified	0.004	0.996	0.000
Q17.8 Other specified congenital malformations of ear	0.004	0.996	0.000
Q17.4 Misplaced ear	0.004	0.996	0.000
Q17.3 Other misshapen ear	0.004	0.996	0.000
Q17.2 Microtia	0.004	0.996	0.000
Q17.1 Macrotia	0.004	0.996	0.000
Q17.0 Accessory auricle	0.004	0.996	0.000
Q60-Q64 Congenital malformations of the urinary system	0.004	0.996	0.000
Q11.3 Macrophthalmos	0.004	0.996	0.000
Q11.2 Microphthalmos	0.004	0.996	0.000
Q11.1 Other anophthalmos	0.004	0.996	0.000
Q11.0 Cystic eyeball	0.004	0.996	0.000
Q13.9 Congenital malformation of anterior segment of eye, unspecified	0.004	0.996	0.000
Q13.8 Other congenital malformations of anterior segment of eye	0.004	0.996	0.000
Q13.5 Blue sclera	0.004	0.996	0.000
Q13.4 Other congenital corneal malformations	0.004	0.996	0.000
Q13.3 Congenital corneal opacity	0.004	0.996	0.000
Q13.2 Other congenital malformations of iris	0.004	0.996	0.000
Q13.1 Absence of iris	0.004	0.996	0.000
Q13.0 Coloboma of iris	0.004	0.996	0.000
Q15.9 Congenital malformation of eye, unspecified	0.004	0.996	0.000
Q15.8 Other specified congenital malformations of eye	0.004	0.996	0.000
Q15.0 Congenital glaucoma	0.004	0.996	0.000
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified	0.004	0.996	0.000
Q16.5 Congenital malformation of inner ear	0.004	0.996	0.000
Q16.4 Other congenital malformations of middle ear	0.004	0.996	0.000
Q16.3 Congenital malformation of ear ossicles	0.004	0.996	0.000
Q16.2 Absence of eustachian tube	0.004	0.996	0.000
Q16.1 Congenital absence, atresia and stricture of auditory canal (external)	0.004	0.996	0.000
Q16.0 Congenital absence of (ear) auricle	0.004	0.996	0.000
B06 Rubella [German measles]	0.004	0.996	0.000
B05 Measles	0.004	0.996	0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.004	0.996	0.000
B04 Monkeypox	0.004	0.996	0.000
B03 Smallpox	0.004	0.996	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.004	0.996	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.004	0.996	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.004	0.996	0.000
Q75 Other congenital malformations of skull and face bones	0.004	0.996	0.000
Q73 Reduction defects of unspecified limb	0.004	0.996	0.000
Q72 Reduction defects of lower limb	0.004	0.996	0.000
Q71 Reduction defects of upper limb	0.004	0.996	0.000
Q70 Syndactyly	0.004	0.996	0.000
Q69 Polydactyly	0.004	0.996	0.000
Q68 Other congenital musculoskeletal deformities	0.004	0.996	0.000
Y44.2 Anticoagulants	0.004	0.996	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.004	0.996	0.000
B00.3 Herpesviral meningitis	0.004	0.996	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.996	0.004
Q79.6 Ehlers-Danlos syndrome	0.004	0.996	0.000
Q66.7 Pes cavus	0.004	0.996	0.000
Q05.9 Spina bifida, unspecified	0.004	0.996	0.000
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.004	0.996	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.004	0.996	0.000
Q39 Congenital malformations of oesophagus	0.004	0.996	0.000
C50.5 Lower-outer quadrant of breast	0.000	0.996	0.004
R03 Abnormal blood-pressure reading, without diagnosis	0.000	0.996	0.004
Q67.6 Pectus excavatum	0.004	0.996	0.000
Q66.9 Congenital deformity of feet, unspecified	0.004	0.996	0.000
Q66.5 Congenital pes planus	0.004	0.996	0.000
Q66.4 Talipes calcaneovalgus	0.004	0.996	0.000
Q66.1 Talipes calcaneovarus	0.004	0.996	0.000
Q66.0 Talipes equinovarus	0.004	0.996	0.000
B01.8 Varicella with other complications	0.004	0.996	0.000
Q35-Q37 Cleft lip and cleft palate	0.004	0.996	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.004	0.996	0.000
Q74 Other congenital malformations of limb(s)	0.004	0.996	0.000
Q67.8 Other congenital deformities of chest	0.004	0.996	0.000
Q67.7 Pectus carinatum	0.004	0.996	0.000
Q67.3 Plagiocephaly	0.004	0.996	0.000
Q67.2 Dolichocephaly	0.004	0.996	0.000
Q67.1 Compression facies	0.004	0.996	0.000
Q67.0 Facial asymmetry	0.004	0.996	0.000
M65.34 Trigger finger-Hand	0.004	0.996	0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.004	0.996	0.000
I51.9 Heart disease, unspecified	0.000	0.996	0.004
Q60.2 Renal agenesis, unspecified	0.004	0.996	0.000
Q39.4 Oesophageal web	0.004	0.996	0.000
R03.1 Nonspecific low blood-pressure reading	0.000	0.996	0.004
Q03 Congenital hydrocephalus	0.003	0.996	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.003	0.996	0.000
B00.8 Other forms of herpesviral infection	0.003	0.996	0.000
B00.7 Disseminated herpesviral disease	0.003	0.996	0.000
B00.0 Eczema herpeticum	0.003	0.996	0.000
Q66.2 Metatarsus varus	0.003	0.996	0.000
D73 Diseases of spleen	0.004	0.996	0.000
C50 Malignant neoplasm of breast	0.000	0.996	0.004
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.996	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.000	0.996	0.003
Q66.8 Other congenital deformities of feet	0.003	0.997	0.000
S32.50 Fracture of pubis (closed)	0.000	0.997	0.003
Q76.0 Spina bifida occulta	0.003	0.997	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.000	0.997	0.003
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.000	0.997	0.003
Q06 Other congenital malformations of spinal cord	0.003	0.997	0.000
Q01 Encephalocele	0.003	0.997	0.000
Q00 Anencephaly and similar malformations	0.003	0.997	0.000
Q02 Microcephaly	0.003	0.997	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.003	0.997	0.000
Q76.8 Other congenital malformations of bony thorax	0.003	0.997	0.000
Q76.7 Congenital malformation of sternum	0.003	0.997	0.000
Q76.6 Other congenital malformations of ribs	0.003	0.997	0.000
Q76.5 Cervical rib	0.003	0.997	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.003	0.997	0.000
Q76.2 Congenital spondylolisthesis	0.003	0.997	0.000
Q76.1 Klippel-Feil syndrome	0.003	0.997	0.000
Q78.0 Osteogenesis imperfecta	0.003	0.997	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.003	0.997	0.000
Q79.5 Other congenital malformations of abdominal wall	0.003	0.997	0.000
Q79.4 Prune belly syndrome	0.003	0.997	0.000
Q79.3 Gastroschisis	0.003	0.997	0.000
Q79.2 Exomphalos	0.003	0.997	0.000
Q79.1 Other congenital malformations of diaphragm	0.003	0.997	0.000
Q79.0 Congenital diaphragmatic hernia	0.003	0.997	0.000
B01.2 Varicella pneumonia	0.003	0.997	0.000
B01.1 Varicella encephalitis	0.003	0.997	0.000
B01.0 Varicella meningitis	0.003	0.997	0.000
N64.9 Disorder of breast, unspecified	0.003	0.997	0.000
Q30 Congenital malformations of nose	0.003	0.997	0.000
D72 Other disorders of white blood cells	0.003	0.997	0.000
R20.2 Paraesthesia of skin	0.000	0.997	0.003
Q05.8 Sacral spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.003	0.997	0.000
Q04 Other congenital malformations of brain	0.003	0.997	0.000
Q50-Q56 Congenital malformations of genital organs	0.003	0.997	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.003	0.997	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.997	0.003
Q78.9 Osteochondrodysplasia, unspecified	0.003	0.997	0.000
Q78.8 Other specified osteochondrodysplasias	0.003	0.997	0.000
Q78.6 Multiple congenital exostoses	0.003	0.997	0.000
Q78.5 Metaphyseal dysplasia	0.003	0.997	0.000
Q78.4 Enchondromatosis	0.003	0.997	0.000
Q78.3 Progressive diaphyseal dysplasia	0.003	0.997	0.000
Q78.2 Osteopetrosis	0.003	0.997	0.000
Q78.1 Polyostotic fibrous dysplasia	0.003	0.997	0.000
B05.9 Measles without complication	0.003	0.997	0.000
B05.8 Measles with other complications	0.003	0.997	0.000
B05.4 Measles with intestinal complications	0.003	0.997	0.000
B05.3 Measles complicated by otitis media	0.003	0.997	0.000
B05.2 Measles complicated by pneumonia	0.003	0.997	0.000
B05.1 Measles complicated by meningitis	0.003	0.997	0.000
B05.0 Measles complicated by encephalitis	0.003	0.997	0.000
B06.9 Rubella without complication	0.003	0.997	0.000
B06.8 Rubella with other complications	0.003	0.997	0.000
B06.0 Rubella with neurological complications	0.003	0.997	0.000
Q39.6 Diverticulum of oesophagus	0.003	0.997	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.003	0.997	0.000
Q65 Congenital deformities of hip	0.003	0.997	0.000
Q60.0 Renal agenesis, unilateral	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
B00.5 Herpesviral ocular disease	0.003	0.997	0.000
B01.9 Varicella without complications	0.003	0.997	0.000
Q43 Other congenital malformations of intestine	0.003	0.997	0.000
Q61 Cystic kidney disease	0.003	0.997	0.000
Q61.5 Medullary cystic kidney	0.003	0.997	0.000
S61.8 Open wound of other parts of wrist and hand	0.000	0.997	0.003
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q07 Other congenital malformations of nervous system	0.003	0.997	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.003	0.997	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.003	0.997	0.000
Q68.4 Congenital bowing of tibia and fibula	0.003	0.997	0.000
Q68.3 Congenital bowing of femur	0.003	0.997	0.000
Q68.2 Congenital deformity of knee	0.003	0.997	0.000
Q68.1 Congenital deformity of hand	0.003	0.997	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.003	0.997	0.000
Q69.9 Polydactyly, unspecified	0.003	0.997	0.000
Q69.2 Accessory toe(s)	0.003	0.997	0.000
Q69.1 Accessory thumb(s)	0.003	0.997	0.000
Q69.0 Accessory finger(s)	0.003	0.997	0.000
Q70.9 Syndactyly, unspecified	0.003	0.997	0.000
Q70.4 Polysyndactyly	0.003	0.997	0.000
Q70.3 Webbed toes	0.003	0.997	0.000
Q70.2 Fused toes	0.003	0.997	0.000
Q70.1 Webbed fingers	0.003	0.997	0.000
Q70.0 Fused fingers	0.003	0.997	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.003	0.997	0.000
Q71.8 Other reduction defects of upper limb(s)	0.003	0.997	0.000
Q71.6 Lobster-claw hand	0.003	0.997	0.000
Q71.5 Longitudinal reduction defect of ulna	0.003	0.997	0.000
Q71.4 Longitudinal reduction defect of radius	0.003	0.997	0.000
Q71.3 Congenital absence of hand and finger(s)	0.003	0.997	0.000
Q71.2 Congenital absence of both forearm and hand	0.003	0.997	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.003	0.997	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.003	0.997	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.003	0.997	0.000
Q72.8 Other reduction defects of lower limb(s)	0.003	0.997	0.000
Q72.7 Split foot	0.003	0.997	0.000
Q72.6 Longitudinal reduction defect of fibula	0.003	0.997	0.000
Q72.5 Longitudinal reduction defect of tibia	0.003	0.997	0.000
Q72.4 Longitudinal reduction defect of femur	0.003	0.997	0.000
Q72.3 Congenital absence of foot and toe(s)	0.003	0.997	0.000
Q72.2 Congenital absence of both lower leg and foot	0.003	0.997	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.003	0.997	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.003	0.997	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.003	0.997	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.003	0.997	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.003	0.997	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.003	0.997	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.003	0.997	0.000
Q75.5 Oculomandibular dysostosis	0.003	0.997	0.000
Q75.4 Mandibulofacial dysostosis	0.003	0.997	0.000
Q75.3 Macrocephaly	0.003	0.997	0.000
Q75.2 Hypertelorism	0.003	0.997	0.000
Q75.1 Craniofacial dysostosis	0.003	0.997	0.000
Q75.0 Craniosynostosis	0.003	0.997	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.003	0.997	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.003	0.997	0.000
Q77.6 Chondroectodermal dysplasia	0.003	0.997	0.000
Q77.5 Diastrophic dysplasia	0.003	0.997	0.000
Q77.4 Achondroplasia	0.003	0.997	0.000
Q77.3 Chondrodysplasia punctata	0.003	0.997	0.000
Q77.2 Short rib syndrome	0.003	0.997	0.000
Q77.1 Thanatophoric short stature	0.003	0.997	0.000
Q77.0 Achondrogenesis	0.003	0.997	0.000
Q34 Other congenital malformations of respiratory system	0.003	0.997	0.000
Q33 Congenital malformations of lung	0.003	0.997	0.000
Q32 Congenital malformations of trachea and bronchus	0.003	0.997	0.000
Q31 Congenital malformations of larynx	0.003	0.997	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.003	0.997	0.000
C50.0 Nipple and areola	0.000	0.997	0.003
Q60.6 Potter's syndrome	0.003	0.997	0.000
Q60.5 Renal hypoplasia, unspecified	0.003	0.997	0.000
Q60.4 Renal hypoplasia, bilateral	0.003	0.997	0.000
Q60.3 Renal hypoplasia, unilateral	0.003	0.997	0.000
Q60.1 Renal agenesis, bilateral	0.003	0.997	0.000
K74 Fibrosis and cirrhosis of liver	0.000	0.997	0.003
B00.9 Herpesviral infection, unspecified	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.003	0.997	0.000
Q39.8 Other congenital malformations of oesophagus	0.003	0.997	0.000
Q39.5 Congenital dilatation of oesophagus	0.003	0.997	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.003	0.997	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.003	0.997	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.003	0.997	0.000
Q39.0 Atresia of oesophagus without fistula	0.003	0.997	0.000
Q64 Other congenital malformations of urinary system	0.003	0.997	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.000	0.997	0.003
Q63 Other congenital malformations of kidney	0.003	0.997	0.000
E10.1 With ketoacidosis	0.000	0.997	0.003
Q37 Cleft palate with cleft lip	0.003	0.997	0.000
Q36 Cleft lip	0.003	0.997	0.000
Q35 Cleft palate	0.003	0.997	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.003	0.997	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.003	0.997	0.000
Q74.3 Arthrogryposis multiplex congenita	0.003	0.997	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.003	0.997	0.000
Z72.1 Alcohol use	0.000	0.997	0.003
Q52 Other congenital malformations of female genitalia	0.003	0.997	0.000
B00.4 Herpesviral encephalitis	0.003	0.997	0.000
B08.8 Other specified viral infections characterised by skin and mucous membrane lesions	0.003	0.997	0.000
B08.5 Enteroviral vesicular pharyngitis	0.003	0.997	0.000
B08.4 Enteroviral vesicular stomatitis with exanthem	0.003	0.997	0.000
B08.3 Erythema infectiosum [fifth disease]	0.003	0.997	0.000
B08.2 Exanthema subitum [sixth disease]	0.003	0.997	0.000
B08.0 Other orthopoxvirus infections	0.003	0.997	0.000
C50.6 Axillary tail of breast	0.000	0.997	0.003
Q03.9 Congenital hydrocephalus, unspecified	0.003	0.997	0.000
Q03.8 Other congenital hydrocephalus	0.003	0.997	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.003	0.997	0.000
Q30.3 Congenital perforated nasal septum	0.003	0.997	0.000
C50.8 Overlapping lesion of breast	0.000	0.997	0.003
Q62.3 Other obstructive defects of renal pelvis and ureter	0.003	0.997	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.003	0.997	0.000
D73.9 Disease of spleen, unspecified	0.003	0.997	0.000
D73.4 Cyst of spleen	0.003	0.997	0.000
D73.3 Abscess of spleen	0.003	0.997	0.000
D73.2 Chronic congestive splenomegaly	0.003	0.997	0.000
N64.5 Other signs and symptoms in breast	0.003	0.997	0.000
E10.2 With renal complications	0.000	0.997	0.003
Q99 Other chromosome abnormalities, not elsewhere classified	0.003	0.997	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
Q90 Down's syndrome	0.003	0.997	0.000
E10.9 Without complications	0.000	0.997	0.003
N10 Acute tubulo-interstitial nephritis	0.003	0.997	0.000
Q74.1 Congenital malformation of knee	0.003	0.997	0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.000	0.997	0.003
M95.8 Other specified acquired deformities of musculoskeletal system	0.000	0.997	0.003
M95.5 Acquired deformity of pelvis	0.000	0.997	0.003
M95.4 Acquired deformity of chest and rib	0.000	0.997	0.003
M95.1 Cauliflower ear	0.000	0.997	0.003
D68.2 Hereditary deficiency of other clotting factors	0.003	0.997	0.000
D73.8 Other diseases of spleen	0.003	0.997	0.000
M95.2 Other acquired deformity of head	0.000	0.997	0.003
Q00.2 Iniencephaly	0.002	0.997	0.000
Q00.1 Craniorachischisis	0.002	0.997	0.000
Q00.0 Anencephaly	0.002	0.997	0.000
Q01.9 Encephalocele, unspecified	0.002	0.997	0.000
Q01.8 Encephalocele of other sites	0.002	0.997	0.000
Q01.2 Occipital encephalocele	0.002	0.997	0.000
Q01.1 Nasofrontal encephalocele	0.002	0.997	0.000
Q01.0 Frontal encephalocele	0.002	0.997	0.000
Q06.9 Congenital malformation of spinal cord, unspecified	0.002	0.997	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.002	0.997	0.000
Q06.4 Hydromyelia	0.002	0.997	0.000
Q06.3 Other congenital cauda equina malformations	0.002	0.997	0.000
Q06.2 Diastematomyelia	0.002	0.997	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.002	0.997	0.000
Q06.0 Amyelia	0.002	0.997	0.000
Q43.0 Meckel's diverticulum	0.003	0.997	0.000
Q61.0 Congenital single renal cyst	0.003	0.997	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.002	0.997	0.000
Q54 Hypospadias	0.003	0.997	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.003	0.997	0.000
D73.5 Infarction of spleen	0.003	0.997	0.000
D73.1 Hypersplenism	0.003	0.997	0.000
Q30.9 Congenital malformation of nose, unspecified	0.002	0.997	0.000
Q30.8 Other congenital malformations of nose	0.002	0.997	0.000
Q30.2 Fissured, notched and cleft nose	0.002	0.997	0.000
Q30.1 Agenesis and underdevelopment of nose	0.002	0.997	0.000
Q30.0 Choanal atresia	0.002	0.997	0.000
Q53 Undescended testicle	0.003	0.997	0.000
D72.9 Disorder of white blood cells, unspecified	0.002	0.997	0.000
D72.0 Genetic anomalies of leukocytes	0.002	0.997	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.997	0.003
Q43.3 Congenital malformations of intestinal fixation	0.002	0.997	0.000
Q61.9 Cystic kidney disease, unspecified	0.003	0.997	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.003	0.997	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.997	0.000
Q04.9 Congenital malformation of brain, unspecified	0.002	0.997	0.000
Q04.8 Other specified congenital malformations of brain	0.002	0.997	0.000
Q04.5 Megalencephaly	0.002	0.997	0.000
Q04.4 Septo-optic dysplasia	0.002	0.997	0.000
Q04.3 Other reduction deformities of brain	0.002	0.997	0.000
Q04.2 Holoprosencephaly	0.002	0.997	0.000
Q04.1 Arhinencephaly	0.002	0.997	0.000
Q04.0 Congenital malformations of corpus callosum	0.002	0.997	0.000
Q44.6 Cystic disease of liver	0.002	0.997	0.000
Q62.8 Other congenital malformations of ureter	0.002	0.997	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.002	0.997	0.000
Q62.6 Malposition of ureter	0.002	0.997	0.000
Q62.4 Agenesis of ureter	0.002	0.997	0.000
Q62.2 Congenital megaloureter	0.002	0.997	0.000
Q62.1 Atresia and stenosis of ureter	0.002	0.997	0.000
Q62.0 Congenital hydronephrosis	0.002	0.997	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.003	0.997	0.000
Q65.9 Congenital deformity of hip, unspecified	0.002	0.997	0.000
Q65.6 Unstable hip	0.002	0.997	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.002	0.997	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.002	0.997	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.002	0.997	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.002	0.997	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.002	0.997	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.002	0.997	0.000
Q44.7 Other congenital malformations of liver	0.002	0.997	0.000
Q44.5 Other congenital malformations of bile ducts	0.002	0.997	0.000
Q44.4 Choledochal cyst	0.002	0.997	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.002	0.997	0.000
Q44.2 Atresia of bile ducts	0.002	0.997	0.000
Q44.1 Other congenital malformations of gallbladder	0.002	0.997	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.002	0.997	0.000
Q52.5 Fusion of labia	0.002	0.997	0.000
Q63.0 Accessory kidney	0.003	0.997	0.000
Q55 Other congenital malformations of male genital organs	0.002	0.997	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.003	0.997	0.000
M95.3 Acquired deformity of neck	0.000	0.997	0.002
Q43.7 Persistent cloaca	0.002	0.997	0.000
Q43.6 Congenital fistula of rectum and anus	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations