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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12070935
log Bayes Factor = 15.5963
Chromosome 1   position 5,091,631  (GRCh37) Explore rs12070935 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.996 0.004 0.000
Chapter II Neoplasms
0.995 0.005 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.994 0.006 0.000
Chapter IX Diseases of the circulatory system
0.993 0.007 0.000
J09-J18 Influenza and pneumonia
0.993 0.007 0.000
J18 Pneumonia, organism unspecified
0.987 0.013 0.000
Chapter XIV Diseases of the genitourinary system
0.986 0.014 0.000
Chapter VIII Diseases of the ear and mastoid process
0.982 0.018 0.000
C15-C26 Malignant neoplasms of digestive organs
0.981 0.019 0.000
J18.1 Lobar pneumonia, unspecified
0.975 0.025 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.975 0.025 0.000
Chapter XXI Factors influencing health status and contact with health services
0.975 0.025 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.973 0.027 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.972 0.028 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.971 0.029 0.000
H90-H95 Other disorders of ear
0.971 0.029 0.000
M70-M79 Other soft tissue disorders
0.970 0.030 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.964 0.036 0.000
Chapter I Certain infectious and parasitic diseases
0.962 0.038 0.000
I30-I52 Other forms of heart disease
0.959 0.041 0.000
J20-J22 Other acute lower respiratory infections
0.956 0.044 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.955 0.045 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.952 0.048 0.000
M45-M49 Spondylopathies
0.952 0.048 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.949 0.051 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.949 0.051 0.000
T81 Complications of procedures, not elsewhere classified
0.947 0.053 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.945 0.055 0.000
I73 Other peripheral vascular diseases
0.937 0.063 0.000
J22 Unspecified acute lower respiratory infection
0.924 0.076 0.000
M75 Shoulder lesions
0.923 0.077 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.921 0.079 0.000
I95 Hypotension
0.917 0.083 0.000
M50-M54 Other dorsopathies
0.917 0.083 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.911 0.089 0.000
B95-B98 Bacterial, viral and other infectious agents
0.910 0.090 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.909 0.091 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.905 0.095 0.000
Chapter VI Diseases of the nervous system
0.904 0.096 0.000
J90-J94 Other diseases of pleura
0.904 0.096 0.000
I73.9 Peripheral vascular disease, unspecified
0.900 0.100 0.000
H91 Other hearing loss
0.895 0.105 0.000
Y83.6 Removal of other organ (partial) (total)
0.895 0.105 0.000
M54 Dorsalgia
0.891 0.109 0.000
M47 Spondylosis
0.889 0.111 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.886 0.114 0.000
J18.9 Pneumonia, unspecified
0.881 0.119 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.880 0.120 0.000
I95.9 Hypotension, unspecified
0.880 0.120 0.000
M15-M19 Arthrosis
0.879 0.121 0.000
N40-N51 Diseases of male genital organs
0.864 0.136 0.000
C15 Malignant neoplasm of oesophagus
0.863 0.137 0.000
H93 Other disorders of ear, not elsewhere classified
0.863 0.137 0.000
Z42 Follow-up care involving plastic surgery
0.863 0.137 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.862 0.138 0.000
Chapter VII Diseases of the eye and adnexa
0.859 0.141 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.859 0.141 0.000
C18 Malignant neoplasm of colon
0.858 0.142 0.000
A00-A09 Intestinal infectious diseases
0.857 0.143 0.000
O80-O84 Delivery
0.857 0.143 0.000
C77.2 Intra-abdominal lymph nodes
0.857 0.143 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.856 0.144 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.852 0.148 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.850 0.150 0.000
Z53.0 Procedure not carried out because of contraindication
0.849 0.151 0.000
I78 Diseases of capillaries
0.849 0.151 0.000
Z46 Fitting and adjustment of other devices
0.848 0.152 0.000
Z53.8 Procedure not carried out for other reasons
0.848 0.152 0.000
M75.4 Impingement syndrome of shoulder
0.845 0.155 0.000
I45 Other conduction disorders
0.844 0.156 0.000
C25 Malignant neoplasm of pancreas
0.843 0.157 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.841 0.159 0.000
H91.9 Hearing loss, unspecified
0.841 0.159 0.000
N10-N16 Renal tubulo-interstitial diseases
0.839 0.161 0.000
M75.5 Bursitis of shoulder
0.839 0.161 0.000
H90 Conductive and sensorineural hearing loss
0.838 0.162 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.838 0.162 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.834 0.166 0.000
Z40 Prophylactic surgery
0.832 0.168 0.000
M54.5 Low back pain
0.831 0.169 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.827 0.173 0.000
I50 Heart failure
0.825 0.175 0.000
M16 Coxarthrosis [arthrosis of hip]
0.823 0.177 0.000
I35 Nonrheumatic aortic valve disorders
0.821 0.179 0.000
M47.8 Other spondylosis
0.821 0.179 0.000
N17-N19 Renal failure
0.820 0.180 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.819 0.181 0.000
O60-O75 Complications of labour and delivery
0.818 0.182 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.817 0.183 0.000
T66-T78 Other and unspecified effects of external causes
0.817 0.183 0.000
C77.3 Axillary and upper limb lymph nodes
0.816 0.184 0.000
H92 Otalgia and effusion of ear
0.816 0.184 0.000
O16 Unspecified maternal hypertension
0.815 0.185 0.000
N60-N64 Disorders of breast
0.815 0.185 0.000
C60-C63 Malignant neoplasms of male genital organs
0.814 0.186 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.813 0.187 0.000
C16 Malignant neoplasm of stomach
0.808 0.192 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.807 0.193 0.000
M16.1 Other primary coxarthrosis
0.803 0.197 0.000
N00-N08 Glomerular diseases
0.802 0.198 0.000
Y43 Primarily systemic agents
0.799 0.201 0.000
Y83.4 Other reconstructive surgery
0.798 0.202 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.797 0.203 0.000
C20 Malignant neoplasm of rectum
0.794 0.205 0.000
C79 Secondary malignant neoplasm of other sites
0.794 0.206 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.793 0.207 0.000
W20-W49 Exposure to inanimate mechanical forces
0.792 0.208 0.000
Z51 Other medical care
0.791 0.209 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.790 0.210 0.000
J93 Pneumothorax
0.787 0.213 0.000
I42 Cardiomyopathy
0.787 0.213 0.000
Z48 Other surgical follow-up care
0.787 0.213 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.786 0.214 0.000
H93.1 Tinnitus
0.786 0.214 0.000
N99-N99 Other disorders of the genitourinary system
0.783 0.217 0.000
M54.9 Dorsalgia, unspecified
0.783 0.217 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.783 0.217 0.000
N20-N23 Urolithiasis
0.781 0.219 0.000
S50-S59 Injuries to the elbow and forearm
0.780 0.220 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.780 0.220 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.779 0.221 0.000
I36 Nonrheumatic tricuspid valve disorders
0.779 0.221 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.778 0.222 0.000
C50-C50 Malignant neoplasm of breast
0.777 0.223 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.776 0.224 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.776 0.224 0.000
S20-S29 Injuries to the thorax
0.774 0.226 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.774 0.226 0.000
G40-G47 Episodic and paroxysmal disorders
0.773 0.227 0.000
N42 Other disorders of prostate
0.772 0.228 0.000
N50 Other disorders of male genital organs
0.772 0.228 0.000
N73 Other female pelvic inflammatory diseases
0.771 0.229 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.771 0.229 0.000
J10 Influenza due to identified influenza virus
0.770 0.230 0.000
T82.3 Mechanical complication of other vascular grafts
0.770 0.230 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.769 0.231 0.000
M65-M68 Disorders of synovium and tendon
0.769 0.231 0.000
M48 Other spondylopathies
0.769 0.231 0.000
H53-H54 Visual disturbances and blindness
0.765 0.235 0.000
I95.1 Orthostatic hypotension
0.764 0.236 0.000
N25-N29 Other disorders of kidney and ureter
0.763 0.237 0.000
M40-M43 Deforming dorsopathies
0.762 0.238 0.000
I78.1 Naevus, nonneoplastic
0.761 0.239 0.000
Z46.6 Fitting and adjustment of urinary device
0.760 0.240 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.759 0.241 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.759 0.241 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.756 0.244 0.000
I73.0 Raynaud's syndrome
0.756 0.244 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.756 0.244 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.756 0.244 0.000
H60-H62 Diseases of external ear
0.755 0.245 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.755 0.245 0.000
M80-M85 Disorders of bone density and structure
0.754 0.246 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.752 0.248 0.000
I38 Endocarditis, valve unspecified
0.752 0.248 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.751 0.249 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.751 0.249 0.000
I49 Other cardiac arrhythmias
0.749 0.251 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.749 0.251 0.000
O80 Single spontaneous delivery
0.749 0.251 0.000
S90-S99 Injuries to the ankle and foot
0.744 0.256 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.744 0.256 0.000
Z51.1 Chemotherapy session for neoplasm
0.744 0.256 0.000
J90 Pleural effusion, not elsewhere classified
0.744 0.256 0.000
Y83.9 Surgical procedure, unspecified
0.742 0.258 0.000
Z45 Adjustment and management of implanted device
0.740 0.260 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.740 0.260 0.000
O42 Premature rupture of membranes
0.738 0.262 0.000
V10-V19 Pedal cyclist injured in transport accident
0.738 0.262 0.000
M71 Other bursopathies
0.738 0.262 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.737 0.263 0.000
N64 Other disorders of breast
0.737 0.263 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.736 0.264 0.000
J00-J06 Acute upper respiratory infections
0.736 0.264 0.000
M86-M90 Other osteopathies
0.735 0.265 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.734 0.266 0.000
C85.1 B-cell lymphoma, unspecified
0.734 0.266 0.000
M45 Ankylosing spondylitis
0.733 0.267 0.000
J60-J70 Lung diseases due to external agents
0.733 0.267 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.732 0.268 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.730 0.270 0.000
I74 Arterial embolism and thrombosis
0.729 0.271 0.000
B25-B34 Other viral diseases
0.729 0.271 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.729 0.271 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.729 0.271 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.729 0.271 0.000
S70-S79 Injuries to the hip and thigh
0.728 0.272 0.000
T79-T79 Certain early complications of trauma
0.728 0.272 0.000
C15.9 Oesophagus, unspecified
0.726 0.274 0.000
Z41 Procedures for purposes other than remedying health state
0.725 0.275 0.000
C92 Myeloid leukaemia
0.725 0.275 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.725 0.275 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.724 0.276 0.000
M47.9 Spondylosis, unspecified
0.723 0.277 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.723 0.277 0.000
Y43.3 Other antineoplastic drugs
0.723 0.277 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.722 0.278 0.000
M79.6 Pain in limb
0.722 0.278 0.000
C18.9 Colon, unspecified
0.721 0.279 0.000
Chapter XXII Codes for special purposes
0.720 0.280 0.000
N20 Calculus of kidney and ureter
0.719 0.280 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.719 0.281 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.719 0.281 0.000
J95-J99 Other diseases of the respiratory system
0.718 0.282 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
S10-S19 Injuries to the neck
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V80-V89 Other land transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V20-V29 Motorcycle rider injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
O85-O92 Complications predominantly related to the puerperium
0.714 0.286 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.713 0.287 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.713 0.287 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.713 0.287 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.713 0.287 0.000
I46 Cardiac arrest
0.713 0.287 0.000
I45.1 Other and unspecified right bundle-branch block
0.713 0.287 0.000
T87 Complications peculiar to reattachment and amputation
0.712 0.287 0.000
T86 Failure and rejection of transplanted organs and tissues
0.712 0.287 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.712 0.287 0.000
C15.5 Lower third of oesophagus
0.712 0.288 0.000
I00-I02 Acute rheumatic fever
0.712 0.288 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.712 0.288 0.000
J17 Pneumonia in diseases classified elsewhere
0.712 0.288 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.712 0.288 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.712 0.288 0.000
J12 Viral pneumonia, not elsewhere classified
0.712 0.288 0.000
J11 Influenza, virus not identified
0.712 0.288 0.000
J14 Pneumonia due to Haemophilus influenzae
0.712 0.288 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.712 0.288 0.000
J09 Influenza due to certain identified influenza virus
0.712 0.288 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.712 0.288 0.000
C77.1 Intrathoracic lymph nodes
0.711 0.289 0.000
Z43 Attention to artificial openings
0.710 0.290 0.000
M75.3 Calcific tendinitis of shoulder
0.710 0.290 0.000
M77 Other enthesopathies
0.709 0.291 0.000
O00-O08 Pregnancy with abortive outcome
0.708 0.292 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.708 0.292 0.000
M54.3 Sciatica
0.708 0.292 0.000
J18.8 Other pneumonia, organism unspecified
0.707 0.293 0.000
J18.2 Hypostatic pneumonia, unspecified
0.707 0.293 0.000
J18.0 Bronchopneumonia, unspecified
0.707 0.293 0.000
X60-X84 Intentional self-harm
0.707 0.293 0.000
I31 Other diseases of pericardium
0.707 0.293 0.000
D00-D09 In situ neoplasms
0.706 0.294 0.000
H92.0 Otalgia
0.705 0.295 0.000
Y95 Nosocomial condition
0.705 0.295 0.000
N50.8 Other specified disorders of male genital organs
0.705 0.295 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.704 0.296 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.704 0.296 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.704 0.296 0.000
C21 Malignant neoplasm of anus and anal canal
0.704 0.296 0.000
C17 Malignant neoplasm of small intestine
0.704 0.296 0.000
C23 Malignant neoplasm of gallbladder
0.704 0.296 0.000
I50.9 Heart failure, unspecified
0.702 0.298 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.702 0.298 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.701 0.299 0.000
H53 Visual disturbances
0.700 0.299 0.000
I77 Other disorders of arteries and arterioles
0.700 0.300 0.000
O15 Eclampsia
0.699 0.301 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.699 0.301 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.699 0.301 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.699 0.301 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.699 0.301 0.000
H80-H83 Diseases of inner ear
0.698 0.302 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.697 0.303 0.000
I72 Other aneurysm
0.697 0.303 0.000
I70 Atherosclerosis
0.697 0.303 0.000
Z54 Convalescence
0.696 0.304 0.000
Z52 Donors of organs and tissues
0.696 0.304 0.000
Z49 Care involving dialysis
0.696 0.304 0.000
Z44 Fitting and adjustment of external prosthetic device
0.696 0.304 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.696 0.304 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.696 0.304 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.696 0.304 0.000
M76 Enthesopathies of lower limb, excluding foot
0.696 0.304 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.696 0.304 0.000
J94 Other pleural conditions
0.695 0.305 0.000
N73.6 Female pelvic peritoneal adhesions
0.694 0.306 0.000
I45.9 Conduction disorder, unspecified
0.694 0.306 0.000
C25.0 Head of pancreas
0.693 0.306 0.000
D50-D53 Nutritional anaemias
0.693 0.307 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.693 0.307 0.000
N19 Unspecified renal failure
0.692 0.308 0.000
Y83.5 Amputation of limb(s)
0.691 0.308 0.000
Y83.0 Surgical operation with transplant of whole organ
0.691 0.308 0.000
I35.0 Aortic (valve) stenosis
0.691 0.309 0.000
G43 Migraine
0.690 0.310 0.000
N48 Other disorders of penis
0.690 0.310 0.000
Y83.8 Other surgical procedures
0.690 0.310 0.000
B99-B99 Other infectious diseases
0.690 0.310 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.690 0.310 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.690 0.310 0.000
B65-B83 Helminthiases
0.690 0.310 0.000
B50-B64 Protozoal diseases
0.690 0.310 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.690 0.310 0.000
B15-B19 Viral hepatitis
0.690 0.310 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.690 0.310 0.000
A80-A89 Viral infections of the central nervous system
0.690 0.310 0.000
A75-A79 Rickettsioses
0.690 0.310 0.000
A70-A74 Other diseases caused by chlamydiae
0.690 0.310 0.000
A65-A69 Other spirochaetal diseases
0.690 0.310 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.690 0.310 0.000
A20-A28 Certain zoonotic bacterial diseases
0.690 0.310 0.000
A15-A19 Tuberculosis
0.690 0.310 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.688 0.311 0.000
T78 Adverse effects, not elsewhere classified
0.688 0.312 0.000
N42.8 Other specified disorders of prostate
0.688 0.312 0.000
I52 Other heart disorders in diseases classified elsewhere
0.687 0.312 0.000
I48 Atrial fibrillation and flutter
0.687 0.312 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.687 0.312 0.000
I41 Myocarditis in diseases classified elsewhere
0.687 0.312 0.000
I40 Acute myocarditis
0.687 0.312 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.687 0.312 0.000
I37 Pulmonary valve disorders
0.687 0.312 0.000
I33 Acute and subacute endocarditis
0.687 0.312 0.000
I32 Pericarditis in diseases classified elsewhere
0.687 0.312 0.000
I30 Acute pericarditis
0.687 0.312 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.687 0.313 0.000
O43 Placental disorders
0.687 0.313 0.000
M46 Other inflammatory spondylopathies
0.687 0.313 0.000
J93.9 Pneumothorax, unspecified
0.687 0.313 0.000
N20.0 Calculus of kidney
0.686 0.314 0.000
C25.9 Pancreas, unspecified
0.685 0.315 0.000
J21 Acute bronchiolitis
0.685 0.315 0.000
J20 Acute bronchitis
0.685 0.315 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.685 0.315 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.685 0.315 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.685 0.315 0.000
T85.2 Mechanical complication of intraocular lens
0.685 0.315 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.685 0.315 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.685 0.315 0.000
C61 Malignant neoplasm of prostate
0.684 0.316 0.000
Z53.9 Procedure not carried out, unspecified reason
0.684 0.316 0.000
C16.0 Cardia
0.684 0.316 0.000
C80 Malignant neoplasm without specification of site
0.683 0.317 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.683 0.317 0.000
M49 Spondylopathies in diseases classified elsewhere
0.682 0.318 0.000
I05-I09 Chronic rheumatic heart diseases
0.682 0.318 0.000
I35.9 Aortic valve disorder, unspecified
0.681 0.319 0.000
B35-B49 Mycoses
0.681 0.319 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.680 0.320 0.000
I99 Other and unspecified disorders of circulatory system
0.680 0.320 0.000
M54.56 Low back pain (Lumbar region)
0.680 0.320 0.000
L20-L30 Dermatitis and eczema
0.680 0.320 0.000
T81.9 Unspecified complication of procedure
0.679 0.321 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.679 0.321 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.679 0.321 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.679 0.321 0.000
Z47 Other orthopaedic follow-up care
0.679 0.321 0.000
H90.5 Sensorineural hearing loss, unspecified
0.678 0.321 0.000
S80-S89 Injuries to the knee and lower leg
0.678 0.322 0.000
O70 Perineal laceration during delivery
0.678 0.322 0.000
Y57 Other and unspecified drugs and medicaments
0.678 0.322 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.677 0.322 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.677 0.322 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.677 0.322 0.000
T82.1 Mechanical complication of cardiac electronic device
0.677 0.322 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.677 0.322 0.000
A04 Other bacterial intestinal infections
0.675 0.325 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.675 0.325 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.674 0.326 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.674 0.326 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.674 0.326 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.674 0.326 0.000
M47.89 Other spondylosis (Site unspecified)
0.673 0.327 0.000
M47.82 Other spondylosis (Cervical region)
0.673 0.327 0.000
M05-M14 Inflammatory polyarthropathies
0.672 0.328 0.000
I73.8 Other specified peripheral vascular diseases
0.672 0.328 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.672 0.328 0.000
A08 Viral and other specified intestinal infections
0.670 0.330 0.000
M47.86 Other spondylosis (Lumbar region)
0.669 0.331 0.000
S40-S49 Injuries to the shoulder and upper arm
0.668 0.332 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.667 0.333 0.000
I71 Aortic aneurysm and dissection
0.666 0.334 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.665 0.335 0.000
I50.1 Left ventricular failure
0.664 0.336 0.000
Y83.3 Surgical operation with formation of external stoma
0.663 0.337 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.663 0.337 0.000
M75.8 Other shoulder lesions
0.662 0.338 0.000
M75.9 Shoulder lesion, unspecified
0.662 0.338 0.000
M75.2 Bicipital tendinitis
0.662 0.338 0.000
H90.2 Conductive hearing loss, unspecified
0.661 0.338 0.000
S60-S69 Injuries to the wrist and hand
0.661 0.339 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.660 0.340 0.000
M54.1 Radiculopathy
0.660 0.340 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.660 0.340 0.000
I34 Nonrheumatic mitral valve disorders
0.659 0.341 0.000
Y86 Sequelae of other accidents
0.658 0.342 0.000
I95.8 Other hypotension
0.658 0.342 0.000
I95.2 Hypotension due to drugs
0.658 0.342 0.000
I95.0 Idiopathic hypotension
0.658 0.342 0.000
M19 Other arthrosis
0.658 0.342 0.000
M53 Other dorsopathies, not elsewhere classified
0.657 0.342 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.657 0.343 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.657 0.343 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.657 0.343 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.656 0.344 0.000
G35 Multiple sclerosis
0.655 0.345 0.000
N03 Chronic nephritic syndrome
0.655 0.345 0.000
J91 Pleural effusion in conditions classified elsewhere
0.654 0.346 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.653 0.347 0.000
C95 Leukaemia of unspecified cell type
0.653 0.347 0.000
C94 Other leukaemias of specified cell type
0.653 0.347 0.000
C93 Monocytic leukaemia
0.653 0.347 0.000
C88 Malignant immunoproliferative diseases
0.653 0.347 0.000
C86 Other specified types of T/NK-cell lymphoma
0.653 0.347 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.653 0.347 0.000
C81 Hodgkin's disease
0.653 0.347 0.000
H10-H13 Disorders of conjunctiva
0.653 0.347 0.000
C77.8 Lymph nodes of multiple regions
0.652 0.348 0.000
C77.4 Inguinal and lower limb lymph nodes
0.652 0.348 0.000
D60-D64 Aplastic and other anaemias
0.652 0.348 0.000
C18.6 Descending colon
0.651 0.349 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.650 0.350 0.000
H90.3 Sensorineural hearing loss, bilateral
0.649 0.350 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.649 0.351 0.000
Y59 Other and unspecified vaccines and biological substances
0.649 0.351 0.000
Y58 Bacterial vaccines
0.649 0.351 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.649 0.351 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.649 0.351 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.649 0.351 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.649 0.351 0.000
Y52 Agents primarily affecting the cardiovascular system
0.649 0.351 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.649 0.351 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.649 0.351 0.000
Y48 Anaesthetics and therapeutic gases
0.649 0.351 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.649 0.351 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.649 0.351 0.000
Y44 Agents primarily affecting blood constituents
0.649 0.351 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.649 0.351 0.000
Y40 Systemic antibiotics
0.649 0.351 0.000
H30-H36 Disorders of choroid and retina
0.649 0.351 0.000
G70-G73 Diseases of myoneural junction and muscle
0.648 0.351 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.648 0.351 0.000
N75 Diseases of Bartholin's gland
0.648 0.352 0.000
S20 Superficial injury of thorax
0.648 0.352 0.000
M79.8 Other specified soft tissue disorders
0.648 0.352 0.000
M75.1 Rotator cuff syndrome
0.647 0.352 0.000
G62 Other polyneuropathies
0.647 0.352 0.000
O42.9 Premature rupture of membranes, unspecified
0.646 0.354 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.645 0.355 0.000
N43 Hydrocele and spermatocele
0.644 0.356 0.000
J40-J47 Chronic lower respiratory diseases
0.643 0.356 0.000
C79.2 Secondary malignant neoplasm of skin
0.643 0.357 0.000
N70 Salpingitis and oophoritis
0.642 0.358 0.000
C18.2 Ascending colon
0.642 0.358 0.000
H91.8 Other specified hearing loss
0.642 0.358 0.000
H91.3 Deaf mutism, not elsewhere classified
0.642 0.358 0.000
H91.2 Sudden idiopathic hearing loss
0.642 0.358 0.000
H91.1 Presbycusis
0.642 0.358 0.000
H91.0 Ototoxic hearing loss
0.642 0.358 0.000
W25 Contact with sharp glass
0.639 0.361 0.000
M54.8 Other dorsalgia
0.639 0.361 0.000
M54.6 Pain in thoracic spine
0.639 0.361 0.000
M54.4 Lumbago with sciatica
0.639 0.361 0.000
M54.0 Panniculitis affecting regions of neck and back
0.639 0.361 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.638 0.362 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.638 0.362 0.000
M47.2 Other spondylosis with radiculopathy
0.637 0.363 0.000
M47.1 Other spondylosis with myelopathy
0.637 0.363 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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