TreeWAS – Variant ID: rs12091709

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E05.9 Thyrotoxicosis, unspecified	0.051	0.949	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.044	0.956	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.043	0.957	0.000
N48.6 Balanitis xerotica obliterans	0.039	0.961	0.000
I73.9 Peripheral vascular disease, unspecified	0.035	0.965	0.000
E05.5 Thyroid crisis or storm	0.032	0.968	0.000
E05.4 Thyrotoxicosis factitia	0.032	0.968	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.032	0.968	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.032	0.968	0.000
E05.8 Other thyrotoxicosis	0.031	0.969	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.027	0.973	0.000
N80.1 Endometriosis of ovary	0.000	0.976	0.024
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.022	0.978	0.000
I73 Other peripheral vascular diseases	0.021	0.979	0.000
E03.9 Hypothyroidism, unspecified	0.021	0.979	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.020	0.980	0.000
E00-E07 Disorders of thyroid gland	0.019	0.981	0.000
E03 Other hypothyroidism	0.019	0.981	0.000
I70 Atherosclerosis	0.018	0.981	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.019	0.981	0.000
I74 Arterial embolism and thrombosis	0.018	0.982	0.000
I74.5 Embolism and thrombosis of iliac artery	0.016	0.984	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.016	0.984	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.016	0.984	0.000
I77.1 Stricture of artery	0.016	0.984	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.016	0.984	0.000
I73.8 Other specified peripheral vascular diseases	0.015	0.985	0.000
I77 Other disorders of arteries and arterioles	0.015	0.985	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.014	0.986	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.014	0.986	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.014	0.986	0.000
E03.5 Myxoedema coma	0.014	0.986	0.000
E03.4 Atrophy of thyroid (acquired)	0.014	0.986	0.000
E03.3 Postinfectious hypothyroidism	0.014	0.986	0.000
E03.1 Congenital hypothyroidism without goitre	0.014	0.986	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.014	0.986	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.014	0.986	0.000
E00 Congenital iodine-deficiency syndrome	0.014	0.986	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.014	0.986	0.000
I70.8 Atherosclerosis of other arteries	0.014	0.986	0.000
I70.9 Generalised and unspecified atherosclerosis	0.013	0.986	0.000
I74.8 Embolism and thrombosis of other arteries	0.013	0.987	0.000
I71 Aortic aneurysm and dissection	0.013	0.987	0.000
I70.0 Atherosclerosis of aorta	0.012	0.987	0.000
E06 Thyroiditis	0.012	0.987	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.012	0.988	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.012	0.988	0.000
E03.8 Other specified hypothyroidism	0.012	0.988	0.000
I70.1 Atherosclerosis of renal artery	0.012	0.988	0.000
E07 Other disorders of thyroid	0.012	0.988	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.011	0.988	0.000
I79.1 Aortitis in diseases classified elsewhere	0.011	0.988	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.011	0.988	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.011	0.988	0.000
I71.0 Dissection of aorta [any part]	0.012	0.988	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.012	0.988	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.012	0.988	0.000
I77.2 Rupture of artery	0.011	0.988	0.000
I77.5 Necrosis of artery	0.011	0.989	0.000
I77.4 Coeliac artery compression syndrome	0.011	0.989	0.000
I77.3 Arterial fibromuscular dysplasia	0.011	0.989	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.011	0.989	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.010	0.990	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.010	0.990	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.010	0.990	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.010	0.990	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.010	0.990	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.010	0.990	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.010	0.990	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.010	0.990	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.010	0.990	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.010	0.990	0.000
E06.1 Subacute thyroiditis	0.010	0.990	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.010	0.990	0.000
N42.2 Atrophy of prostate	0.010	0.990	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.010	0.990	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.010	0.990	0.000
I72 Other aneurysm	0.009	0.990	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.010	0.990	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.009	0.990	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.009	0.990	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.009	0.990	0.000
Q21.1 Atrial septal defect	0.009	0.991	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.009	0.991	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.009	0.991	0.000
E06.5 Other chronic thyroiditis	0.009	0.991	0.000
E06.4 Drug-induced thyroiditis	0.009	0.991	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.009	0.991	0.000
E06.0 Acute thyroiditis	0.009	0.991	0.000
Y45.0 Opioids and related analgesics	0.000	0.991	0.009
I77.0 Arteriovenous fistula, acquired	0.009	0.991	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.009	0.991	0.000
Q61.0 Congenital single renal cyst	0.009	0.991	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.009	0.991	0.000
E07.1 Dyshormogenetic goitre	0.009	0.991	0.000
E07.0 Hypersecretion of calcitonin	0.009	0.991	0.000
E06.9 Thyroiditis, unspecified	0.009	0.991	0.000
E07.9 Disorder of thyroid, unspecified	0.009	0.991	0.000
I77.6 Arteritis, unspecified	0.008	0.992	0.000
I72.3 Aneurysm of iliac artery	0.008	0.992	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.008	0.992	0.000
Q61 Cystic kidney disease	0.008	0.992	0.000
Q21 Congenital malformations of cardiac septa	0.008	0.992	0.000
I72.2 Aneurysm of renal artery	0.007	0.992	0.000
I72.1 Aneurysm of artery of upper extremity	0.007	0.992	0.000
E07.8 Other specified disorders of thyroid	0.007	0.992	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.007	0.992	0.000
I72.4 Aneurysm of artery of lower extremity	0.007	0.993	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.007	0.993	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.007	0.993	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.000	0.993	0.007
Q61.5 Medullary cystic kidney	0.007	0.993	0.000
Q61.3 Polycystic kidney, unspecified	0.007	0.993	0.000
E06.3 Autoimmune thyroiditis	0.007	0.993	0.000
Q60-Q64 Congenital malformations of the urinary system	0.007	0.993	0.000
Q21.3 Tetralogy of Fallot	0.007	0.993	0.000
Q21.0 Ventricular septal defect	0.006	0.993	0.000
Y45.1 Salicylates	0.000	0.994	0.006
Q21.9 Congenital malformation of cardiac septum, unspecified	0.006	0.994	0.000
I72.9 Aneurysm of unspecified site	0.006	0.994	0.000
Y45.5 4-Aminophenol derivatives	0.000	0.994	0.006
Q61.8 Other cystic kidney diseases	0.006	0.994	0.000
Q61.4 Renal dysplasia	0.006	0.994	0.000
Q61.1 Polycystic kidney, infantile type	0.006	0.994	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.006	0.994	0.000
Q21.8 Other congenital malformations of cardiac septa	0.006	0.994	0.000
Q21.4 Aortopulmonary septal defect	0.006	0.994	0.000
Q21.2 Atrioventricular septal defect	0.006	0.994	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.006	0.994	0.000
Y45.2 Propionic acid derivatives	0.000	0.994	0.006
I77.8 Other specified disorders of arteries and arterioles	0.005	0.994	0.000
N80.3 Endometriosis of pelvic peritoneum	0.000	0.994	0.006
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.000	0.994	0.006
Q60.2 Renal agenesis, unspecified	0.005	0.994	0.000
Q64 Other congenital malformations of urinary system	0.005	0.995	0.000
Q61.2 Polycystic kidney, adult type	0.005	0.995	0.000
Q61.9 Cystic kidney disease, unspecified	0.005	0.995	0.000
Y45.4 Antirheumatics	0.000	0.995	0.005
H65.9 Nonsuppurative otitis media, unspecified	0.005	0.995	0.000
I78 Diseases of capillaries	0.005	0.995	0.000
Q25 Congenital malformations of great arteries	0.005	0.995	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.005	0.995	0.000
L53.9 Erythematous condition, unspecified	0.005	0.995	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.005	0.995	0.000
N80 Endometriosis	0.000	0.995	0.005
I72.0 Aneurysm of carotid artery	0.004	0.995	0.001
C91.1 Chronic lymphocytic leukaemia	0.000	0.995	0.005
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.995	0.005
Z98.1 Arthrodesis status	0.000	0.995	0.005
Q27 Other congenital malformations of peripheral vascular system	0.005	0.995	0.000
Y45.8 Other analgesics and antipyretics	0.000	0.995	0.005
Q60.0 Renal agenesis, unilateral	0.005	0.995	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.995	0.005
Q60.6 Potter's syndrome	0.004	0.995	0.000
Q60.5 Renal hypoplasia, unspecified	0.004	0.995	0.000
Q60.4 Renal hypoplasia, bilateral	0.004	0.995	0.000
Q60.3 Renal hypoplasia, unilateral	0.004	0.995	0.000
Q60.1 Renal agenesis, bilateral	0.004	0.995	0.000
Q26 Congenital malformations of great veins	0.004	0.995	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.004	0.995	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.004	0.995	0.000
Q63 Other congenital malformations of kidney	0.005	0.995	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.995	0.005
H65.2 Chronic serous otitis media	0.005	0.995	0.000
N85.0 Endometrial glandular hyperplasia	0.005	0.995	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.004	0.995	0.000
Q28 Other congenital malformations of circulatory system	0.004	0.996	0.000
Q25.1 Coarctation of aorta	0.004	0.996	0.000
Q25.6 Stenosis of pulmonary artery	0.004	0.996	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.004	0.996	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.004	0.996	0.000
Q35-Q37 Cleft lip and cleft palate	0.004	0.996	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.004	0.996	0.000
Q64.8 Other specified congenital malformations of urinary system	0.004	0.996	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.004	0.996	0.000
Q64.6 Congenital diverticulum of bladder	0.004	0.996	0.000
Q64.5 Congenital absence of bladder and urethra	0.004	0.996	0.000
Q64.4 Malformation of urachus	0.004	0.996	0.000
Q64.2 Congenital posterior urethral valves	0.004	0.996	0.000
Q64.1 Exstrophy of urinary bladder	0.004	0.996	0.000
Q64.0 Epispadias	0.004	0.996	0.000
T68 Hypothermia	0.004	0.996	0.000
I72.8 Aneurysm of other specified arteries	0.002	0.996	0.002
I78.9 Disease of capillaries, unspecified	0.004	0.996	0.000
H65 Nonsuppurative otitis media	0.004	0.996	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.004	0.996	0.000
Q25.8 Other congenital malformations of great arteries	0.004	0.996	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.004	0.996	0.000
Q25.5 Atresia of pulmonary artery	0.004	0.996	0.000
Q25.3 Stenosis of aorta	0.004	0.996	0.000
Q25.2 Atresia of aorta	0.004	0.996	0.000
Q25.0 Patent ductus arteriosus	0.004	0.996	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.004	0.996	0.000
Q62.8 Other congenital malformations of ureter	0.004	0.996	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.004	0.996	0.000
Q62.6 Malposition of ureter	0.004	0.996	0.000
Q62.5 Duplication of ureter	0.004	0.996	0.000
Q62.4 Agenesis of ureter	0.004	0.996	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.004	0.996	0.000
Q62.2 Congenital megaloureter	0.004	0.996	0.000
Q62.1 Atresia and stenosis of ureter	0.004	0.996	0.000
Q62.0 Congenital hydronephrosis	0.004	0.996	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.996	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.004	0.996	0.000
Q25.4 Other congenital malformations of aorta	0.004	0.996	0.000
N80.4 Endometriosis of rectovaginal septum and vagina	0.000	0.996	0.004
T63.4 Venom of other arthropods	0.004	0.996	0.000
X23.9 Unspecified place	0.004	0.996	0.000
Q80-Q89 Other congenital malformations	0.004	0.996	0.000
I78.8 Other diseases of capillaries	0.004	0.996	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.004	0.996	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.004	0.996	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.004	0.996	0.000
Z99.2 Dependence on renal dialysis	0.000	0.996	0.004
N80.5 Endometriosis of intestine	0.000	0.996	0.004
Q27.4 Congenital phlebectasia	0.004	0.996	0.000
Q27.2 Other congenital malformations of renal artery	0.004	0.996	0.000
Q27.1 Congenital renal artery stenosis	0.004	0.996	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.004	0.996	0.000
Q24 Other congenital malformations of heart	0.004	0.996	0.000
Q90 Down's syndrome	0.004	0.996	0.000
T78 Adverse effects, not elsewhere classified	0.004	0.996	0.000
N80.6 Endometriosis in cutaneous scar	0.000	0.996	0.004
Q37 Cleft palate with cleft lip	0.004	0.996	0.000
H65.0 Acute serous otitis media	0.004	0.996	0.000
Q23 Congenital malformations of aortic and mitral valves	0.003	0.996	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.004	0.996	0.000
Q63.2 Ectopic kidney	0.003	0.996	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.003	0.996	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.003	0.996	0.000
Q20.6 Isomerism of atrial appendages	0.003	0.996	0.000
Q20.5 Discordant atrioventricular connexion	0.003	0.996	0.000
Q20.4 Double inlet ventricle	0.003	0.996	0.000
Q20.3 Discordant ventriculoarterial connexion	0.003	0.996	0.000
Q20.2 Double outlet left ventricle	0.003	0.996	0.000
Q20.1 Double outlet right ventricle	0.003	0.996	0.000
Q20.0 Common arterial trunk	0.003	0.996	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.003	0.996	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.003	0.996	0.000
Q22.6 Hypoplastic right heart syndrome	0.003	0.996	0.000
Q22.5 Ebstein's anomaly	0.003	0.996	0.000
Q22.4 Congenital tricuspid stenosis	0.003	0.996	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.003	0.996	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.003	0.996	0.000
Q22.1 Congenital pulmonary valve stenosis	0.003	0.996	0.000
Q22.0 Pulmonary valve atresia	0.003	0.996	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.003	0.996	0.000
Q26.8 Other congenital malformations of great veins	0.003	0.996	0.000
Q26.6 Portal vein-hepatic artery fistula	0.003	0.996	0.000
Q26.5 Anomalous portal venous connexion	0.003	0.996	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.003	0.996	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.003	0.996	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.003	0.996	0.000
Q26.1 Persistent left superior vena cava	0.003	0.996	0.000
Q26.0 Congenital stenosis of vena cava	0.003	0.996	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.003	0.996	0.000
Q63.8 Other specified congenital malformations of kidney	0.003	0.996	0.000
Q63.3 Hyperplastic and giant kidney	0.003	0.996	0.000
C44.4 Skin of scalp and neck	0.004	0.996	0.000
Q12 Congenital lens malformations	0.003	0.996	0.000
N48 Other disorders of penis	0.003	0.997	0.000
Q15 Other congenital malformations of eye	0.003	0.997	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.003	0.997	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.003	0.997	0.000
Q28.3 Other malformations of cerebral vessels	0.003	0.997	0.000
Q28.1 Other malformations of precerebral vessels	0.003	0.997	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.003	0.997	0.000
L53 Other erythematous conditions	0.003	0.997	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.997	0.003
T66-T78 Other and unspecified effects of external causes	0.003	0.997	0.000
N48.2 Other inflammatory disorders of penis	0.003	0.997	0.000
J00 Acute nasopharyngitis [common cold]	0.003	0.997	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.003	0.997	0.000
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
N80.2 Endometriosis of Fallopian tube	0.000	0.997	0.003
H65.4 Other chronic nonsuppurative otitis media	0.003	0.997	0.000
T71 Asphyxiation	0.003	0.997	0.000
Q76.0 Spina bifida occulta	0.003	0.997	0.000
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
Q36 Cleft lip	0.003	0.997	0.000
Q35 Cleft palate	0.003	0.997	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.003	0.997	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.003	0.997	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.003	0.997	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.003	0.997	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.003	0.997	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.003	0.997	0.000
Q90.9 Down's syndrome, unspecified	0.003	0.997	0.000
T78.4 Allergy, unspecified	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
L53.8 Other specified erythematous conditions	0.003	0.997	0.000
M79.64 Pain in limb (Hand)	0.003	0.997	0.000
Q43 Other congenital malformations of intestine	0.003	0.997	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.003	0.997	0.000
Q37.9 Unspecified cleft palate with unilateral cleft lip	0.003	0.997	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.003	0.997	0.000
Q82 Other congenital malformations of skin	0.003	0.997	0.000
H65.1 Other acute nonsuppurative otitis media	0.003	0.997	0.000
Q27.3 Peripheral arteriovenous malformation	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q12.0 Congenital cataract	0.003	0.997	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.003	0.997	0.000
Q15.0 Congenital glaucoma	0.003	0.997	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.003	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.003	0.997	0.000
Q13 Congenital malformations of anterior segment of eye	0.003	0.997	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.003	0.997	0.000
T78.8 Other adverse effects, not elsewhere classified	0.003	0.997	0.000
Q34 Other congenital malformations of respiratory system	0.003	0.997	0.000
Q33 Congenital malformations of lung	0.003	0.997	0.000
Q32 Congenital malformations of trachea and bronchus	0.003	0.997	0.000
Q31 Congenital malformations of larynx	0.003	0.997	0.000
Q30 Congenital malformations of nose	0.003	0.997	0.000
Q96 Turner's syndrome	0.003	0.997	0.000
T78.9 Adverse effect, unspecified	0.003	0.997	0.000
Q39.6 Diverticulum of oesophagus	0.003	0.997	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.003	0.997	0.000
Q84 Other congenital malformations of integument	0.003	0.997	0.000
Q83 Congenital malformations of breast	0.003	0.997	0.000
Q81 Epidermolysis bullosa	0.003	0.997	0.000
Q80 Congenital ichthyosis	0.003	0.997	0.000
N60.4 Mammary duct ectasia	0.000	0.997	0.003
Q24.5 Malformation of coronary vessels	0.003	0.997	0.000
Q17 Other congenital malformations of ear	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
Q24.6 Congenital heart block	0.003	0.997	0.000
Q24.4 Congenital subaortic stenosis	0.003	0.997	0.000
Q24.3 Pulmonary infundibular stenosis	0.003	0.997	0.000
Q24.2 Cor triatriatum	0.003	0.997	0.000
Q24.1 Levocardia	0.003	0.997	0.000
Q24.0 Dextrocardia	0.003	0.997	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.003	0.997	0.000
F80.1 Expressive language disorder	0.000	0.997	0.003
Q82.0 Hereditary lymphoedema	0.003	0.997	0.000
Q90.2 Trisomy 21, translocation	0.003	0.997	0.000
Q90.1 Trisomy 21, mosaicism (mitotic nondisjunction)	0.003	0.997	0.000
Q90.0 Trisomy 21, meiotic nondisjunction	0.003	0.997	0.000
N48.8 Other specified disorders of penis	0.003	0.997	0.000
Q37.8 Unspecified cleft palate with bilateral cleft lip	0.003	0.997	0.000
Q37.5 Cleft hard and soft palate with unilateral cleft lip	0.003	0.997	0.000
Q37.4 Cleft hard and soft palate with bilateral cleft lip	0.003	0.997	0.000
Q37.3 Cleft soft palate with unilateral cleft lip	0.003	0.997	0.000
Q37.2 Cleft soft palate with bilateral cleft lip	0.003	0.997	0.000
Q37.1 Cleft hard palate with unilateral cleft lip	0.003	0.997	0.000
Q37.0 Cleft hard palate with bilateral cleft lip	0.003	0.997	0.000
Q85 Phakomatoses, not elsewhere classified	0.003	0.997	0.000
H61.0 Perichondritis of external ear	0.000	0.997	0.003
Q89 Other congenital malformations, not elsewhere classified	0.003	0.997	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.003	0.997	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.003	0.997	0.000
Q23.4 Hypoplastic left heart syndrome	0.003	0.997	0.000
Q23.3 Congenital mitral insufficiency	0.003	0.997	0.000
Q23.2 Congenital mitral stenosis	0.003	0.997	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.003	0.997	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q75 Other congenital malformations of skull and face bones	0.003	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.003	0.997	0.000
Q73 Reduction defects of unspecified limb	0.003	0.997	0.000
Q72 Reduction defects of lower limb	0.003	0.997	0.000
Q71 Reduction defects of upper limb	0.003	0.997	0.000
Q70 Syndactyly	0.003	0.997	0.000
Q69 Polydactyly	0.003	0.997	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
Q23.0 Congenital stenosis of aortic valve	0.003	0.997	0.000
Q65 Congenital deformities of hip	0.003	0.997	0.000
Q03 Congenital hydrocephalus	0.003	0.997	0.000
Q78 Other osteochondrodysplasias	0.003	0.997	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.003	0.997	0.000
T66 Unspecified effects of radiation	0.003	0.997	0.000
D37.5 Rectum	0.000	0.997	0.003
Q12.9 Congenital lens malformation, unspecified	0.003	0.997	0.000
Q12.8 Other congenital lens malformations	0.003	0.997	0.000
Q12.4 Spherophakia	0.003	0.997	0.000
Q12.3 Congenital aphakia	0.003	0.997	0.000
Q12.2 Coloboma of lens	0.003	0.997	0.000
Q12.1 Congenital displaced lens	0.003	0.997	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.003	0.997	0.000
Q04 Other congenital malformations of brain	0.003	0.997	0.000
Q15.9 Congenital malformation of eye, unspecified	0.003	0.997	0.000
Q15.8 Other specified congenital malformations of eye	0.003	0.997	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.003	0.997	0.000
Q82.5 Congenital nonneoplastic naevus	0.003	0.997	0.000
L53.3 Other chronic figurate erythema	0.003	0.997	0.000
L53.2 Erythema marginatum	0.003	0.997	0.000
L53.1 Erythema annulare centrifugum	0.003	0.997	0.000
L53.0 Toxic erythema	0.003	0.997	0.000
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.003	0.997	0.000
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.003	0.997	0.000
Q98.7 Male with sex chromosome mosaicism	0.003	0.997	0.000
Q98.6 Male with structurally abnormal sex chromosome	0.003	0.997	0.000
Q98.5 Karyotype 47,XYY	0.003	0.997	0.000
Q98.3 Other male with 46,XX karyotype	0.003	0.997	0.000
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.003	0.997	0.000
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.003	0.997	0.000
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.003	0.997	0.000
Q06 Other congenital malformations of spinal cord	0.003	0.997	0.000
Q01 Encephalocele	0.003	0.997	0.000
Q00 Anencephaly and similar malformations	0.003	0.997	0.000
Q02 Microcephaly	0.003	0.997	0.000
T74 Maltreatment syndromes	0.003	0.997	0.000
T73 Effects of other deprivation	0.003	0.997	0.000
T69 Other effects of reduced temperature	0.003	0.997	0.000
T67 Effects of heat and light	0.003	0.997	0.000
Q76.1 Klippel-Feil syndrome	0.003	0.997	0.000
Q66 Congenital deformities of feet	0.003	0.997	0.000
I87.8 Other specified disorders of veins	0.000	0.997	0.003
Q43.0 Meckel's diverticulum	0.003	0.997	0.000
T46.1 Calcium-channel blockers	0.003	0.997	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.002	0.997	0.001
Q39.9 Congenital malformation of oesophagus, unspecified	0.003	0.997	0.000
Q39.8 Other congenital malformations of oesophagus	0.003	0.997	0.000
Q39.5 Congenital dilatation of oesophagus	0.003	0.997	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.003	0.997	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.003	0.997	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.003	0.997	0.000
Q39.0 Atresia of oesophagus without fistula	0.003	0.997	0.000
I51.7 Cardiomegaly	0.003	0.997	0.000
Q87.4 Marfan's syndrome	0.003	0.997	0.000
T78.2 Anaphylactic shock, unspecified	0.003	0.997	0.000
Q35.9 Cleft palate, unspecified	0.002	0.997	0.000
Q35.8 (Cleft palate, unspecified, bilateral)	0.002	0.997	0.000
Q35.7 Cleft uvula	0.002	0.997	0.000
Q35.6 Cleft palate, medial	0.002	0.997	0.000
Q35.5 Cleft hard palate with cleft soft palate	0.002	0.997	0.000
Q35.4 (Cleft hard palate with cleft soft palate, bilateral)	0.002	0.997	0.000
Q35.3 Cleft soft palate	0.002	0.997	0.000
Q35.2 (Cleft soft palate, bilateral)	0.002	0.997	0.000
Q35.1 Cleft hard palate	0.002	0.997	0.000
Q35.0 (Cleft hard palate, bilateral)	0.002	0.997	0.000
Q36.9 Cleft lip, unilateral	0.002	0.997	0.000
Q36.1 Cleft lip, medial	0.002	0.997	0.000
Q36.0 Cleft lip, bilateral	0.002	0.997	0.000
Q91.7 Patau's syndrome, unspecified	0.002	0.997	0.000
Q91.6 Trisomy 13, translocation	0.002	0.997	0.000
Q91.5 Trisomy 13, mosaicism (mitotic nondisjunction)	0.002	0.997	0.000
Q91.4 Trisomy 13, meiotic nondisjunction	0.002	0.997	0.000
Q91.3 Edwards' syndrome, unspecified	0.002	0.997	0.000
Q91.2 Trisomy 18, translocation	0.002	0.997	0.000
Q91.1 Trisomy 18, mosaicism (mitotic nondisjunction)	0.002	0.997	0.000
Q91.0 Trisomy 18, meiotic nondisjunction	0.002	0.997	0.000
Q92.9 Trisomy and partial trisomy of autosomes, unspecified	0.002	0.997	0.000
Q92.8 Other specified trisomies and partial trisomies of autosomes	0.002	0.997	0.000
Q92.7 Triploidy and polyploidy	0.002	0.997	0.000
Q92.6 Extra marker chromosomes	0.002	0.997	0.000
Q92.5 Duplications with other complex rearrangements	0.002	0.997	0.000
Q92.4 Duplications seen only at prometaphase	0.002	0.997	0.000
Q92.3 Minor partial trisomy	0.002	0.997	0.000
Q92.2 Major partial trisomy	0.002	0.997	0.000
Q92.1 Whole chromosome trisomy, mosaicism (mitotic nondisjunction)	0.002	0.997	0.000
Q92.0 Whole chromosome trisomy, meiotic nondisjunction	0.002	0.997	0.000
Q93.9 Deletion from autosomes, unspecified	0.002	0.997	0.000
Q93.8 Other deletions from the autosomes	0.002	0.997	0.000
Q93.7 Deletions with other complex rearrangements	0.002	0.997	0.000
Q93.6 Deletions seen only at prometaphase	0.002	0.997	0.000
Q93.5 Other deletions of part of a chromosome	0.002	0.997	0.000
Q93.4 Deletion of short arm of chromosome 5	0.002	0.997	0.000
Q93.3 Deletion of short arm of chromosome 4	0.002	0.997	0.000
Q93.2 Chromosome replaced with ring or dicentric	0.002	0.997	0.000
Q93.1 Whole chromosome monosomy, mosaicism (mitotic nondisjunction)	0.002	0.997	0.000
Q93.0 Whole chromosome monosomy, meiotic nondisjunction	0.002	0.997	0.000
Q95.9 Balanced rearrangement and structural marker, unspecified	0.002	0.997	0.000
Q95.8 Other balanced rearrangements and structural markers	0.002	0.997	0.000
Q95.5 Individuals with autosomal fragile site	0.002	0.997	0.000
Q95.4 Individuals with marker heterochromatin	0.002	0.997	0.000
Q95.3 Balanced sex/autosomal rearrangement in abnormal individual	0.002	0.997	0.000
Q95.2 Balanced autosomal rearrangement in abnormal individual	0.002	0.997	0.000
Q95.1 Chromosome inversion in normal individual	0.002	0.997	0.000
Q95.0 Balanced translocation and insertion in normal individual	0.002	0.997	0.000
Q97.9 Sex chromosome abnormality, female phenotype, unspecified	0.002	0.997	0.000
Q97.8 Other specified sex chromosome abnormalities, female phenotype	0.002	0.997	0.000
Q97.3 Female with 46,XY karyotype	0.002	0.997	0.000
Q97.2 Mosaicism, lines with various numbers of X chromosomes	0.002	0.997	0.000
Q97.1 Female with more than three X chromosomes	0.002	0.997	0.000
Q97.0 Karyotype 47,XXX	0.002	0.997	0.000
Q99.9 Chromosomal abnormality, unspecified	0.002	0.997	0.000
Q99.8 Other specified chromosome abnormalities	0.002	0.997	0.000
Q99.2 Fragile X chromosome	0.002	0.997	0.000
Q99.1 46,XX true hermaphrodite	0.002	0.997	0.000
Q99.0 Chimera 46,XX/46,XY	0.002	0.997	0.000
N48.3 Priapism	0.003	0.997	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.002	0.997	0.000
Q76.8 Other congenital malformations of bony thorax	0.002	0.997	0.000
Q76.7 Congenital malformation of sternum	0.002	0.997	0.000
Q76.6 Other congenital malformations of ribs	0.002	0.997	0.000
Q76.5 Cervical rib	0.002	0.997	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.002	0.997	0.000
Q76.2 Congenital spondylolisthesis	0.002	0.997	0.000
N80.8 Other endometriosis	0.000	0.997	0.003
Q43.7 Persistent cloaca	0.002	0.997	0.000
Q43.6 Congenital fistula of rectum and anus	0.002	0.997	0.000
Q43.5 Ectopic anus	0.002	0.997	0.000
Q43.4 Duplication of intestine	0.002	0.997	0.000
Q43.3 Congenital malformations of intestinal fixation	0.002	0.997	0.000
Q43.2 Other congenital functional disorders of colon	0.002	0.997	0.000
Q43.1 Hirschsprung's disease	0.002	0.997	0.000
Q83.1 Accessory breast	0.002	0.997	0.000
N85.9 Noninflammatory disorder of uterus, unspecified	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations