TreeWAS – Variant ID: rs12132423

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
# Top node	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000
Chapter XI Diseases of the digestive system	0.999	0.001
Chapter IX Diseases of the circulatory system	0.999	0.001
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.996	0.004
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.994	0.006
Chapter XV Pregnancy, childbirth and the puerperium	0.993	0.007
I30-I52 Other forms of heart disease	0.993	0.007
K50-K52 Noninfective enteritis and colitis	0.992	0.008
K52 Other non-infective gastro-enteritis and colitis	0.990	0.010
Chapter VI Diseases of the nervous system	0.990	0.010
Chapter X Diseases of the respiratory system	0.988	0.012
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.987	0.013
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.986	0.014
Chapter IV Endocrine, nutritional and metabolic diseases	0.986	0.014
Chapter XX External causes of morbidity and mortality	0.982	0.018
O60-O75 Complications of labour and delivery	0.976	0.024
J40-J47 Chronic lower respiratory diseases	0.976	0.024
Chapter XXI Factors influencing health status and contact with health services	0.973	0.027
K55-K64 Other diseases of intestines	0.973	0.027
K58 Irritable bowel syndrome	0.972	0.028
K58.9 Irritable bowel syndrome without diarrhoea	0.972	0.028
E70-E90 Metabolic disorders	0.969	0.031
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.967	0.033
G40-G47 Episodic and paroxysmal disorders	0.965	0.035
Chapter V Mental and behavioural disorders	0.957	0.043
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.956	0.044
I47 Paroxysmal tachycardia	0.956	0.044
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.955	0.045
J47 Bronchiectasis	0.951	0.049
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.950	0.050
S60-S69 Injuries to the wrist and hand	0.950	0.050
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.948	0.052
R79 Other abnormal findings of blood chemistry	0.944	0.056
Z40-Z54 Persons encountering health services for specific procedures and health care	0.942	0.058
I95-I99 Other and unspecified disorders of the circulatory system	0.940	0.060
I51 Complications and ill-defined descriptions of heart disease	0.938	0.062
R26 Abnormalities of gait and mobility	0.938	0.062
Z50 Care involving use of rehabilitation procedures	0.936	0.064
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.934	0.066
R79.8 Other specified abnormal findings of blood chemistry	0.928	0.072
I47.1 Supraventricular tachycardia	0.926	0.074
Z47 Other orthopaedic follow-up care	0.925	0.075
E87 Other disorders of fluid, electrolyte and acid-base balance	0.920	0.080
T36-T50 Poisoning by drugs, medicaments and biological substances	0.920	0.080
M05-M14 Inflammatory polyarthropathies	0.919	0.081
Z50.1 Other physical therapy	0.919	0.081
G40 Epilepsy	0.918	0.082
R25 Abnormal involuntary movements	0.913	0.087
I60-I69 Cerebrovascular diseases	0.911	0.089
T81 Complications of procedures, not elsewhere classified	0.910	0.090
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.907	0.093
J09-J18 Influenza and pneumonia	0.904	0.096
S00-S09 Injuries to the head	0.903	0.097
Z60 Problems related to social environment	0.903	0.097
O70 Perineal laceration during delivery	0.901	0.099
R29.6 Tendency to fall, not elsewhere classified	0.901	0.099
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.899	0.101
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.898	0.102
R30-R39 Symptoms and signs involving the urinary system	0.896	0.104
S70-S79 Injuries to the hip and thigh	0.895	0.105
I95 Hypotension	0.892	0.108
I63 Cerebral infarction	0.882	0.118
G90-G99 Other disorders of the nervous system	0.881	0.119
Z60.2 Living alone	0.880	0.120
S80-S89 Injuries to the knee and lower leg	0.879	0.121
R26.8 Other and unspecified abnormalities of gait and mobility	0.879	0.121
M15-M19 Arthrosis	0.877	0.123
O70.1 Second degree perineal laceration during delivery	0.872	0.128
O68 Labour and delivery complicated by foetal stress [distress]	0.870	0.130
T66-T78 Other and unspecified effects of external causes	0.862	0.138
T84.0 Mechanical complication of internal joint prosthesis	0.857	0.143
M10 Gout	0.857	0.143
G47 Sleep disorders	0.856	0.144
S61 Open wound of wrist and hand	0.855	0.145
R42 Dizziness and giddiness	0.855	0.145
K52.8 Other specified non-infective gastro-enteritis and colitis	0.853	0.147
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.851	0.149
R33 Retention of urine	0.848	0.152
I95.9 Hypotension, unspecified	0.848	0.152
O42 Premature rupture of membranes	0.848	0.152
I63.9 Cerebral infarction, unspecified	0.847	0.153
J44 Other chronic obstructive pulmonary disease	0.847	0.153
K90-K93 Other diseases of the digestive system	0.847	0.153
M19 Other arthrosis	0.841	0.159
J43 Emphysema	0.841	0.159
K35-K38 Diseases of appendix	0.841	0.159
E65-E68 Obesity and other hyperalimentation	0.837	0.163
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.835	0.165
I70-I79 Diseases of arteries, arterioles and capillaries	0.834	0.166
I51.8 Other ill-defined heart diseases	0.834	0.166
J18 Pneumonia, organism unspecified	0.833	0.166
I38 Endocarditis, valve unspecified	0.833	0.167
I50 Heart failure	0.833	0.167
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.833	0.167
S40-S49 Injuries to the shoulder and upper arm	0.832	0.168
I51.7 Cardiomegaly	0.831	0.169
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.830	0.170
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.828	0.172
G40.9 Epilepsy, unspecified	0.826	0.174
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.826	0.174
Chapter VIII Diseases of the ear and mastoid process	0.826	0.174
M50-M54 Other dorsopathies	0.825	0.175
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.825	0.175
O36 Maternal care for other known or suspected foetal problems	0.823	0.177
E86 Volume depletion	0.823	0.177
G35-G37 Demyelinating diseases of the central nervous system	0.823	0.177
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.820	0.180
O72 Postpartum haemorrhage	0.819	0.181
S69 Other and unspecified injuries of wrist and hand	0.818	0.182
T85 Complications of other internal prosthetic devices, implants and grafts	0.816	0.184
F30-F39 Mood [affective] disorders	0.815	0.185
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.814	0.186
E87.5 Hyperkalaemia	0.813	0.187
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.813	0.187
M10.9 Gout, unspecified	0.812	0.188
I34 Nonrheumatic mitral valve disorders	0.812	0.188
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.810	0.190
E83 Disorders of mineral metabolism	0.810	0.190
Chapter XXII Codes for special purposes	0.809	0.191
M19.9 Arthrosis, unspecified	0.808	0.192
S61.0 Open wound of finger(s) without damage to nail	0.808	0.192
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.807	0.193
J60-J70 Lung diseases due to external agents	0.806	0.194
I42 Cardiomyopathy	0.805	0.195
R39 Other symptoms and signs involving the urinary system	0.804	0.196
J00-J06 Acute upper respiratory infections	0.802	0.198
Chapter II Neoplasms	0.801	0.199
O75 Other complications of labour and delivery, not elsewhere classified	0.800	0.200
J18.1 Lobar pneumonia, unspecified	0.798	0.202
K65-K67 Diseases of peritoneum	0.798	0.202
R25.2 Cramp and spasm	0.798	0.202
M19.99 Arthrosis, unspecified (Site unspecified)	0.794	0.206
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.794	0.206
S82 Fracture of lower leg, including ankle	0.793	0.207
R47-R49 Symptoms and signs involving speech and voice	0.792	0.208
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.790	0.209
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.789	0.211
E87.7 Fluid overload	0.788	0.212
Chapter I Certain infectious and parasitic diseases	0.786	0.214
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.783	0.217
C50-C50 Malignant neoplasm of breast	0.783	0.217
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.781	0.219
R40 Somnolence, stupor and coma	0.779	0.221
R25.1 Tremor, unspecified	0.777	0.223
M10.99 Gout, unspecified (Site unspecified)	0.777	0.223
F40-F48 Neurotic, stress-related and somatoform disorders	0.776	0.224
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.775	0.225
Z50.8 Care involving use of rehabilitation procedures	0.775	0.225
M40-M43 Deforming dorsopathies	0.772	0.227
G20-G26 Extrapyramidal and movement disorders	0.771	0.229
I49 Other cardiac arrhythmias	0.770	0.230
C50 Malignant neoplasm of breast	0.770	0.230
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.768	0.232
O40 Polyhydramnios	0.767	0.233
T81.8 Other complications of procedures, not elsewhere classified	0.767	0.233
S20-S29 Injuries to the thorax	0.767	0.233
M45-M49 Spondylopathies	0.766	0.234
V80-V89 Other land transport accidents	0.766	0.234
S01 Open wound of head	0.766	0.234
S50-S59 Injuries to the elbow and forearm	0.766	0.234
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.766	0.234
M70-M79 Other soft tissue disorders	0.765	0.235
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.763	0.237
Z36 Antenatal screening	0.760	0.240
Z47.8 Other specified orthopaedic follow-up care	0.760	0.240
E20-E35 Disorders of other endocrine glands	0.760	0.240
E87.2 Acidosis	0.757	0.243
G95 Other diseases of spinal cord	0.757	0.243
O80-O84 Delivery	0.757	0.243
I30 Acute pericarditis	0.756	0.244
Y43 Primarily systemic agents	0.755	0.245
J40 Bronchitis, not specified as acute or chronic	0.755	0.245
G44 Other headache syndromes	0.754	0.246
G80-G83 Cerebral palsy and other paralytic syndromes	0.752	0.248
G93 Other disorders of brain	0.752	0.248
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.751	0.249
Y60-Y69 Misadventures to patients during surgical and medical care	0.750	0.250
G00-G09 Inflammatory diseases of the central nervous system	0.749	0.251
R26.2 Difficulty in walking, not elsewhere classified	0.749	0.251
S00 Superficial injury of head	0.747	0.252
R41 Other symptoms and signs involving cognitive functions and awareness	0.747	0.253
F00-F09 Organic, including symptomatic, mental disorders	0.745	0.255
J43.9 Emphysema, unspecified	0.745	0.255
S02 Fracture of skull and facial bones	0.744	0.255
M86-M90 Other osteopathies	0.744	0.255
M50 Cervical disk disorders	0.743	0.257
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.743	0.257
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.741	0.258
C50.4 Upper-outer quadrant of breast	0.741	0.259
S64 Injury of nerves at wrist and hand level	0.741	0.259
S90-S99 Injuries to the ankle and foot	0.741	0.259
T79-T79 Certain early complications of trauma	0.740	0.259
K59 Other functional intestinal disorders	0.740	0.260
M65-M68 Disorders of synovium and tendon	0.739	0.260
W00-W19 Falls	0.739	0.261
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.739	0.261
K60 Fissure and fistula of anal and rectal regions	0.739	0.261
K58.0 Irritable bowel syndrome with diarrhoea	0.739	0.261
O42.9 Premature rupture of membranes, unspecified	0.738	0.262
O69 Labour and delivery complicated by umbilical cord complications	0.737	0.263
S72 Fracture of femur	0.737	0.263
Z35 Supervision of high-risk pregnancy	0.737	0.263
I50.0 Congestive heart failure	0.736	0.264
K55 Vascular disorders of intestine	0.736	0.264
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.735	0.265
T88 Other complications of surgical and medical care, not elsewhere classified	0.735	0.265
O41 Other disorders of amniotic fluid and membranes	0.734	0.266
I63.8 Other cerebral infarction	0.733	0.267
T15-T19 Effects of foreign body entering through natural orifice	0.732	0.268
O48 Prolonged pregnancy	0.731	0.269
E83.5 Disorders of calcium metabolism	0.730	0.270
M80-M85 Disorders of bone density and structure	0.730	0.270
E66 Obesity	0.730	0.270
V10-V19 Pedal cyclist injured in transport accident	0.729	0.271
Y95 Nosocomial condition	0.729	0.271
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.727	0.273
T84.1 Mechanical complication of internal fixation device of bones of limb	0.727	0.273
J44.9 Chronic obstructive pulmonary disease, unspecified	0.726	0.274
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.725	0.275
S61.7 Multiple open wounds of wrist and hand	0.724	0.276
R32 Unspecified urinary incontinence	0.724	0.276
S69.9 Unspecified injury of wrist and hand	0.723	0.277
G47.3 Sleep apnoea	0.721	0.279
T68 Hypothermia	0.721	0.279
M18 Arthrosis of first carpometacarpal joint	0.721	0.279
O30 Multiple gestation	0.719	0.281
I34.1 Mitral (valve) prolapse	0.718	0.282
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S10-S19 Injuries to the neck	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.717	0.283
O47 False labour	0.717	0.283
S68 Traumatic amputation of wrist and hand	0.716	0.284
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.716	0.284
I00-I02 Acute rheumatic fever	0.716	0.284
G47.9 Sleep disorder, unspecified	0.716	0.284
S66 Injury of muscle and tendon at wrist and hand level	0.715	0.285
Z49 Care involving dialysis	0.715	0.285
R27 Other lack of coordination	0.714	0.286
R39.1 Other difficulties with micturition	0.714	0.286
W20-W49 Exposure to inanimate mechanical forces	0.713	0.286
S79 Other and unspecified injuries of hip and thigh	0.713	0.287
Z32 Pregnancy examination and test	0.713	0.287
T87 Complications peculiar to reattachment and amputation	0.713	0.287
T86 Failure and rejection of transplanted organs and tissues	0.713	0.287
T80 Complications following infusion, transfusion and therapeutic injection	0.713	0.287
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.712	0.288
O85-O92 Complications predominantly related to the puerperium	0.712	0.288
I52 Other heart disorders in diseases classified elsewhere	0.712	0.288
I48 Atrial fibrillation and flutter	0.712	0.288
I43 Cardiomyopathy in diseases classified elsewhere	0.712	0.288
I41 Myocarditis in diseases classified elsewhere	0.712	0.288
I40 Acute myocarditis	0.712	0.288
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.712	0.288
I37 Pulmonary valve disorders	0.712	0.288
I36 Nonrheumatic tricuspid valve disorders	0.712	0.288
I33 Acute and subacute endocarditis	0.712	0.288
I32 Pericarditis in diseases classified elsewhere	0.712	0.288
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.712	0.288
I47.2 Ventricular tachycardia	0.711	0.289
O94-O99 Other obstetric conditions, not elsewhere classified	0.711	0.289
X60-X84 Intentional self-harm	0.710	0.289
K52.3 Indeterminate colitis	0.710	0.290
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.710	0.290
K52.1 Toxic gastro-enteritis and colitis	0.710	0.290
K52.0 Gastro-enteritis and colitis due to radiation	0.710	0.290
R92 Abnormal findings on diagnostic imaging of breast	0.710	0.290
G70-G73 Diseases of myoneural junction and muscle	0.710	0.290
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.710	0.290
J95-J99 Other diseases of the respiratory system	0.709	0.290
T81.3 Disruption of operation wound, not elsewhere classified	0.709	0.291
O72.0 Third-stage haemorrhage	0.709	0.291
G30-G32 Other degenerative diseases of the nervous system	0.709	0.291
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.708	0.291
R44 Other symptoms and signs involving general sensations and perceptions	0.708	0.291
I73 Other peripheral vascular diseases	0.708	0.292
F99-F99 Unspecified mental disorder	0.708	0.292
K70-K77 Diseases of liver	0.707	0.293
I98 Other disorders of circulatory system in diseases classified elsewhere	0.707	0.293
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.707	0.293
M91-M94 Chondropathies	0.707	0.293
M60-M63 Disorders of muscles	0.707	0.293
M00-M03 Infectious arthropathies	0.707	0.293
E40-E46 Malnutrition	0.707	0.293
M13 Other arthritis	0.706	0.294
J44.8 Other specified chronic obstructive pulmonary disease	0.705	0.295
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.704	0.296
Y35-Y36 Legal intervention and operations of war	0.704	0.296
Y10-Y34 Event of undetermined intent	0.704	0.296
Y00-Y09 Assault	0.704	0.296
X85-X99 Assault	0.704	0.296
X58-X59 Accidental exposure to other and unspecified factors	0.704	0.296
X50-X57 Overexertion, travel and privation	0.704	0.296
X40-X49 Accidental poisoning by and exposure to noxious substances	0.704	0.296
X30-X39 Exposure to forces of nature	0.704	0.296
X20-X29 Contact with venomous animals and plants	0.704	0.296
X10-X19 Contact with heat and hot substances	0.704	0.296
X00-X09 Exposure to smoke, fire and flames	0.704	0.296
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.704	0.296
W75-W84 Other accidental threats to breathing	0.704	0.296
W65-W74 Accidental drowning and submersion	0.704	0.296
W50-W64 Exposure to animate mechanical forces	0.704	0.296
V98-V99 Other and unspecified transport accidents	0.704	0.296
V95-V97 Air and space transport accidents	0.704	0.296
V90-V94 Water transport accidents	0.704	0.296
V70-V79 Bus occupant injured in transport accident	0.704	0.296
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.704	0.296
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.704	0.296
V40-V49 Car occupant injured in transport accident	0.704	0.296
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.704	0.296
V20-V29 Motorcycle rider injured in transport accident	0.704	0.296
V01-V09 Pedestrian injured in transport accident	0.704	0.296
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.704	0.296
I61 Intracerebral haemorrhage	0.702	0.298
A30-A49 Other bacterial diseases	0.701	0.298
M79 Other soft tissue disorders, not elsewhere classified	0.701	0.299
Z63 Other problems related to primary support group, including family circumstances	0.701	0.299
O74 Complications of anaesthesia during labour and delivery	0.700	0.300
O73 Retained placenta and membranes, without haemorrhage	0.700	0.300
O71 Other obstetric trauma	0.700	0.300
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.700	0.300
O66 Other obstructed labour	0.700	0.300
O65 Obstructed labour due to maternal pelvic abnormality	0.700	0.300
O64 Obstructed labour due to malposition and malpresentation of foetus	0.700	0.300
O62 Abnormalities of forces of labour	0.700	0.300
O61 Failed induction of labour	0.700	0.300
O60 Preterm delivery	0.700	0.300
J41 Simple and mucopurulent chronic bronchitis	0.700	0.300
J46 Status asthmaticus	0.700	0.300
J42 Unspecified chronic bronchitis	0.700	0.300
R45 Symptoms and signs involving emotional state	0.699	0.301
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.699	0.301
T93 Sequelae of injuries of lower limb	0.699	0.301
R72 Abnormality of white blood cells, not elsewhere classified	0.698	0.301
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.698	0.302
K64 Haemorrhoids and perianal venous thrombosis	0.697	0.303
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.697	0.303
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.696	0.304
O36.8 Maternal care for other specified foetal problems	0.696	0.304
Y86 Sequelae of other accidents	0.695	0.304
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.695	0.305
T83.1 Mechanical complication of other urinary devices and implants	0.695	0.305
E88 Other metabolic disorders	0.694	0.306
E85 Amyloidosis	0.694	0.306
E84 Cystic fibrosis	0.694	0.306
E79 Disorders of purine and pyrimidine metabolism	0.694	0.306
E77 Disorders of glycoprotein metabolism	0.694	0.306
E76 Disorders of glycosaminoglycan metabolism	0.694	0.306
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.694	0.306
E74 Other disorders of carbohydrate metabolism	0.694	0.306
E73 Lactose intolerance	0.694	0.306
E72 Other disorders of amino-acid metabolism	0.694	0.306
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.694	0.306
E70 Disorders of aromatic amino-acid metabolism	0.694	0.306
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.694	0.306
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.694	0.306
R78 Findings of drugs and other substances, not normally found in blood	0.693	0.307
R77 Other abnormalities of plasma proteins	0.693	0.307
R76 Other abnormal immunological findings in serum	0.693	0.307
R74 Abnormal serum enzyme levels	0.693	0.307
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.693	0.307
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.693	0.307
R71 Abnormality of red blood cells	0.693	0.307
Y44 Agents primarily affecting blood constituents	0.693	0.307
G46 Vascular syndromes of brain in cerebrovascular diseases	0.692	0.308
G41 Status epilepticus	0.692	0.308
Z30 Contraceptive management	0.692	0.308
S80 Superficial injury of lower leg	0.691	0.308
T78 Adverse effects, not elsewhere classified	0.691	0.309
I51.9 Heart disease, unspecified	0.691	0.309
E10-E14 Diabetes mellitus	0.689	0.311
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.687	0.313
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.686	0.313
F80-F89 Disorders of psychological development	0.686	0.313
F70-F79 Mental retardation	0.686	0.313
F60-F69 Disorders of adult personality and behaviour	0.686	0.313
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.686	0.313
R73 Elevated blood glucose level	0.686	0.314
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.686	0.314
R29.4 Clicking hip	0.685	0.315
R29.3 Abnormal posture	0.685	0.315
R29.2 Abnormal reflex	0.685	0.315
R29.1 Meningismus	0.685	0.315
R29.0 Tetany	0.685	0.315
I47.9 Paroxysmal tachycardia, unspecified	0.685	0.315
I47.0 Reentry ventricular arrhythmia	0.685	0.315
Y40 Systemic antibiotics	0.685	0.315
Z39 Postpartum care and examination	0.685	0.315
O45 Premature separation of placenta [abruptio placentae]	0.684	0.316
O44 Placenta praevia	0.684	0.316
O43 Placental disorders	0.684	0.316
O35 Maternal care for known or suspected foetal abnormality and damage	0.684	0.316
O33 Maternal care for known or suspected disproportion	0.684	0.316
O31 Complications specific to multiple gestation	0.684	0.316
M19.94 Arthrosis, unspecified (Hand)	0.684	0.316
J13 Pneumonia due to Streptococcus pneumoniae	0.684	0.316
H90-H95 Other disorders of ear	0.684	0.316
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.683	0.317
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.681	0.319
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.681	0.319
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.681	0.319
T84.3 Mechanical complication of other bone devices, implants and grafts	0.681	0.319
T84.2 Mechanical complication of internal fixation device of other bones	0.681	0.319
S67 Crushing injury of wrist and hand	0.681	0.319
S65 Injury of blood vessels at wrist and hand level	0.681	0.319
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.681	0.319
S60 Superficial injury of wrist and hand	0.681	0.319
R46 Symptoms and signs involving appearance and behaviour	0.680	0.320
R43 Disturbances of smell and taste	0.680	0.320
G45 Transient cerebral ischaemic attacks and related syndromes	0.679	0.320
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.679	0.321
Z50.5 Speech therapy	0.678	0.322
I78 Diseases of capillaries	0.678	0.322
M06 Other rheumatoid arthritis	0.678	0.322
K90 Intestinal malabsorption	0.677	0.323
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.677	0.323
R79.9 Abnormal finding of blood chemistry, unspecified	0.677	0.323
R79.0 Abnormal level of blood mineral	0.677	0.323
O32 Maternal care for known or suspected malpresentation of foetus	0.677	0.323
Z54 Convalescence	0.675	0.325
Z52 Donors of organs and tissues	0.675	0.325
Z44 Fitting and adjustment of external prosthetic device	0.675	0.325
S00.9 Superficial injury of head, part unspecified	0.675	0.325
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.674	0.326
I99 Other and unspecified disorders of circulatory system	0.674	0.326
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.674	0.326
E87.1 Hypo-osmolality and hyponatraemia	0.674	0.326
T51 Toxic effect of alcohol	0.673	0.326
E66.9 Obesity, unspecified	0.673	0.327
I95.1 Orthostatic hypotension	0.673	0.327
S46 Injury of muscle and tendon at shoulder and upper arm level	0.673	0.327
T81.4 Infection following a procedure, not elsewhere classified	0.673	0.327
I51.6 Cardiovascular disease, unspecified	0.673	0.327
I51.5 Myocardial degeneration	0.673	0.327
I51.4 Myocarditis, unspecified	0.673	0.327
I51.3 Intracardiac thrombosis, not elsewhere classified	0.673	0.327
I51.2 Rupture of papillary muscle, not elsewhere classified	0.673	0.327
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.673	0.327
I51.0 Cardiac septal defect, acquired	0.673	0.327
M50.2 Other cervical disk displacement	0.673	0.327
R26.3 Immobility	0.672	0.328
R26.1 Paralytic gait	0.672	0.328
R26.0 Ataxic gait	0.672	0.328
Z50.6 Orthoptic training	0.671	0.329
Z50.4 Psychotherapy, not elsewhere classified	0.671	0.329
Z50.3 Drug rehabilitation	0.671	0.329
Z50.2 Alcohol rehabilitation	0.671	0.329
Z50.0 Cardiac rehabilitation	0.671	0.329
R47 Speech disturbances, not elsewhere classified	0.670	0.330
Z65 Problems related to other psychosocial circumstances	0.670	0.330
Z64 Problems related to certain psychosocial circumstances	0.670	0.330
Z62 Other problems related to upbringing	0.670	0.330
Z61 Problems related to negative life events in childhood	0.670	0.330
Z59 Problems related to housing and economic circumstances	0.670	0.330
Z58 Problems related to physical environment	0.670	0.330
Z57 Occupational exposure to risk-factors	0.670	0.330
Z56 Problems related to employment and unemployment	0.670	0.330
Z55 Problems related to education and literacy	0.670	0.330
F29 Unspecified nonorganic psychosis	0.669	0.331
K08 Other disorders of teeth and supporting structures	0.667	0.333
J06 Acute upper respiratory infections of multiple and unspecified sites	0.666	0.334
I95.2 Hypotension due to drugs	0.666	0.334
K37 Unspecified appendicitis	0.666	0.334
I26 Pulmonary embolism	0.666	0.334
S01.8 Open wound of other parts of head	0.666	0.334
G35 Multiple sclerosis	0.665	0.335
K40-K46 Hernia	0.665	0.335
I42.0 Dilated cardiomyopathy	0.665	0.335
I69 Sequelae of cerebrovascular disease	0.665	0.335
Z47.9 Orthopaedic follow-up care, unspecified	0.663	0.336
E80 Disorders of porphyrin and bilirubin metabolism	0.662	0.338
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.662	0.338
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.661	0.339
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.660	0.340
E87.4 Mixed disorder of acid-base balance	0.660	0.340
E87.3 Alkalosis	0.660	0.340
E87.0 Hyperosmolality and hypernatraemia	0.660	0.340
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.660	0.340
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.660	0.340
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.660	0.340
T46 Poisoning by agents primarily affecting the cardiovascular system	0.660	0.340
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.660	0.340
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.660	0.340
T41 Poisoning by anaesthetics and therapeutic gases	0.660	0.340
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.660	0.340
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.660	0.340
T36 Poisoning by systemic antibiotics	0.660	0.340
M14 Arthropathies in other diseases classified elsewhere	0.659	0.341
M12 Other specific arthropathies	0.659	0.341
M11 Other crystal arthropathies	0.659	0.341
M09 Juvenile arthritis in diseases classified elsewhere	0.659	0.341
M08 Juvenile arthritis	0.659	0.341
M07 Psoriatic and enteropathic arthropathies	0.659	0.341
M05 Seropositive rheumatoid arthritis	0.659	0.341

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations