TreeWAS – Variant ID: rs12136530

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E04.2 Non-toxic multinodular goitre	0.114	0.886	0.000
E05.9 Thyrotoxicosis, unspecified	0.110	0.890	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.106	0.894	0.000
E04 Other non-toxic goitre	0.101	0.899	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.097	0.903	0.000
E00-E07 Disorders of thyroid gland	0.095	0.905	0.000
E04.1 Non-toxic single thyroid nodule	0.089	0.911	0.000
E05.8 Other thyrotoxicosis	0.082	0.918	0.000
E05.5 Thyroid crisis or storm	0.076	0.924	0.000
E05.4 Thyrotoxicosis factitia	0.076	0.924	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.076	0.924	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.076	0.924	0.000
E04.8 Other specified non-toxic goitre	0.073	0.927	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.068	0.932	0.000
E00 Congenital iodine-deficiency syndrome	0.068	0.932	0.000
E04.0 Non-toxic diffuse goitre	0.068	0.932	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.066	0.934	0.000
E07 Other disorders of thyroid	0.063	0.937	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.062	0.938	0.000
E06 Thyroiditis	0.054	0.946	0.000
E03 Other hypothyroidism	0.052	0.948	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.049	0.951	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.049	0.951	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.049	0.951	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.049	0.951	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.049	0.951	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.049	0.951	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.049	0.951	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.049	0.951	0.000
E07.1 Dyshormogenetic goitre	0.045	0.954	0.000
E07.0 Hypersecretion of calcitonin	0.045	0.954	0.000
E03.8 Other specified hypothyroidism	0.045	0.955	0.000
R41.3 Other amnesia	0.000	0.956	0.044
R41 Other symptoms and signs involving cognitive functions and awareness	0.000	0.956	0.044
E07.9 Disorder of thyroid, unspecified	0.044	0.956	0.000
E07.8 Other specified disorders of thyroid	0.042	0.958	0.000
E06.5 Other chronic thyroiditis	0.042	0.958	0.000
R41.0 Disorientation, unspecified	0.000	0.958	0.042
E03.0 Congenital hypothyroidism with diffuse goitre	0.040	0.960	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.000	0.960	0.040
E06.4 Drug-induced thyroiditis	0.039	0.961	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.039	0.961	0.000
E06.1 Subacute thyroiditis	0.039	0.961	0.000
E06.0 Acute thyroiditis	0.039	0.961	0.000
E03.5 Myxoedema coma	0.038	0.962	0.000
E03.4 Atrophy of thyroid (acquired)	0.038	0.962	0.000
E03.3 Postinfectious hypothyroidism	0.038	0.962	0.000
E03.1 Congenital hypothyroidism without goitre	0.038	0.962	0.000
E06.9 Thyroiditis, unspecified	0.037	0.962	0.000
R41.2 Retrograde amnesia	0.000	0.964	0.036
R41.1 Anterograde amnesia	0.000	0.965	0.034
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.032	0.968	0.000
E04.9 Non-toxic goitre, unspecified	0.022	0.978	0.000
E06.3 Autoimmune thyroiditis	0.020	0.980	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.000	0.989	0.011
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.000	0.991	0.009
R43 Disturbances of smell and taste	0.000	0.991	0.009
S91.1 Open wound of toe(s) without damage to nail	0.008	0.992	0.000
R44.1 Visual hallucinations	0.000	0.992	0.008
S91 Open wound of ankle and foot	0.008	0.992	0.000
R43.8 Other and unspecified disturbances of smell and taste	0.000	0.992	0.008
I35.1 Aortic (valve) insufficiency	0.008	0.992	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.000	0.992	0.008
Y52.4 Angiotensin-converting-enzyme inhibitors	0.008	0.992	0.000
S92.00 Fracture of calcaneus (closed)	0.007	0.993	0.000
S90 Superficial injury of ankle and foot	0.007	0.993	0.000
S91.3 Open wound of other parts of foot	0.007	0.993	0.000
R43.0 Anosmia	0.000	0.993	0.007
S90-S99 Injuries to the ankle and foot	0.007	0.993	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.007	0.993	0.000
N41.0 Acute prostatitis	0.000	0.993	0.007
S90.8 Other superficial injuries of ankle and foot	0.007	0.993	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.007	0.993	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.007	0.993	0.000
Q28 Other congenital malformations of circulatory system	0.007	0.993	0.000
Q80-Q89 Other congenital malformations	0.007	0.993	0.000
Q66 Congenital deformities of feet	0.007	0.993	0.000
S91.0 Open wound of ankle	0.007	0.993	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.007	0.993	0.000
Q66.8 Other congenital deformities of feet	0.007	0.993	0.000
S91.2 Open wound of toe(s) with damage to nail	0.006	0.993	0.000
R43.2 Parageusia	0.000	0.993	0.006
R43.1 Parosmia	0.000	0.993	0.006
S92.0 Fracture of calcaneus	0.006	0.994	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.006	0.994	0.000
S90.0 Contusion of ankle	0.006	0.994	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.006	0.994	0.000
Q83 Congenital malformations of breast	0.006	0.994	0.000
S91.7 Multiple open wounds of ankle and foot	0.006	0.994	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.006	0.994	0.000
S90.1 Contusion of toe(s) without damage to nail	0.006	0.994	0.000
Q40 Other congenital malformations of upper alimentary tract	0.006	0.994	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.006	0.994	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.006	0.994	0.000
R40 Somnolence, stupor and coma	0.000	0.994	0.006
Q39 Congenital malformations of oesophagus	0.006	0.994	0.000
Q38.6 Other congenital malformations of mouth	0.006	0.994	0.000
R44.2 Other hallucinations	0.000	0.994	0.006
S92 Fracture of foot, except ankle	0.006	0.994	0.000
I35.0 Aortic (valve) stenosis	0.006	0.994	0.000
Q83.8 Other congenital malformations of breast	0.006	0.994	0.000
R44.3 Hallucinations, unspecified	0.000	0.994	0.006
Q23 Congenital malformations of aortic and mitral valves	0.006	0.994	0.000
Q87.4 Marfan's syndrome	0.006	0.994	0.000
Z71.3 Dietary counselling and surveillance	0.006	0.994	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.006	0.994	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.006	0.994	0.000
Q66.7 Pes cavus	0.006	0.994	0.000
S99 Other and unspecified injuries of ankle and foot	0.006	0.994	0.000
Q43 Other congenital malformations of intestine	0.006	0.994	0.000
S97 Crushing injury of ankle and foot	0.006	0.994	0.000
J45.0 Predominantly allergic asthma	0.000	0.994	0.006
Q66.0 Talipes equinovarus	0.005	0.994	0.000
Q27 Other congenital malformations of peripheral vascular system	0.005	0.994	0.000
Q25 Congenital malformations of great arteries	0.005	0.994	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.005	0.995	0.000
S90.2 Contusion of toe(s) with damage to nail	0.005	0.995	0.000
Q83.3 Accessory nipple	0.005	0.995	0.000
Q40.1 Congenital hiatus hernia	0.005	0.995	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.005	0.995	0.000
Q45 Other congenital malformations of digestive system	0.005	0.995	0.000
Q39.6 Diverticulum of oesophagus	0.005	0.995	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.005	0.995	0.000
S98 Traumatic amputation of ankle and foot	0.005	0.995	0.000
S95 Injury of blood vessels at ankle and foot level	0.005	0.995	0.000
S94 Injury of nerves at ankle and foot level	0.005	0.995	0.000
R46 Symptoms and signs involving appearance and behaviour	0.000	0.995	0.005
Q42 Congenital absence, atresia and stenosis of large intestine	0.005	0.995	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.005	0.995	0.000
N41.1 Chronic prostatitis	0.000	0.995	0.005
I35 Nonrheumatic aortic valve disorders	0.005	0.995	0.000
Q26 Congenital malformations of great veins	0.005	0.995	0.000
Q24 Other congenital malformations of heart	0.005	0.995	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.005	0.995	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.005	0.995	0.000
Q78 Other osteochondrodysplasias	0.005	0.995	0.000
Z29.0 Isolation	0.000	0.995	0.005
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.005	0.995	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.005	0.995	0.000
S90.3 Contusion of other and unspecified parts of foot	0.005	0.995	0.000
Q82 Other congenital malformations of skin	0.005	0.995	0.000
Q38.7 Pharyngeal pouch	0.005	0.995	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.005	0.995	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.005	0.995	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.005	0.995	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.005	0.995	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.005	0.995	0.000
Q28.3 Other malformations of cerebral vessels	0.005	0.995	0.000
Q28.1 Other malformations of precerebral vessels	0.005	0.995	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.005	0.995	0.000
Q84 Other congenital malformations of integument	0.005	0.995	0.000
Q81 Epidermolysis bullosa	0.005	0.995	0.000
Q80 Congenital ichthyosis	0.005	0.995	0.000
Q66.9 Congenital deformity of feet, unspecified	0.005	0.995	0.000
Q66.6 Other congenital valgus deformities of feet	0.005	0.995	0.000
Q66.5 Congenital pes planus	0.005	0.995	0.000
Q66.4 Talipes calcaneovalgus	0.005	0.995	0.000
Q66.3 Other congenital varus deformities of feet	0.005	0.995	0.000
Q66.1 Talipes calcaneovarus	0.005	0.995	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.005	0.995	0.000
Q23.1 Congenital insufficiency of aortic valve	0.005	0.995	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.005	0.995	0.000
Q38.1 Ankyloglossia	0.005	0.995	0.000
Q66.2 Metatarsus varus	0.005	0.995	0.000
Q35-Q37 Cleft lip and cleft palate	0.005	0.995	0.000
I35.9 Aortic valve disorder, unspecified	0.005	0.995	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.005	0.995	0.000
S92.01 Fracture of calcaneus (open)	0.005	0.995	0.000
Q38.8 Other congenital malformations of pharynx	0.005	0.995	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.005	0.995	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.005	0.995	0.000
Q38.3 Other congenital malformations of tongue	0.005	0.995	0.000
Q38.2 Macroglossia	0.005	0.995	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.005	0.995	0.000
Z29.1 Prophylactic immunotherapy	0.000	0.995	0.005
Q40.8 Other specified congenital malformations of upper alimentary tract	0.005	0.995	0.000
Q67.5 Congenital deformity of spine	0.005	0.995	0.000
Q40.2 Other specified congenital malformations of stomach	0.005	0.995	0.000
Q89 Other congenital malformations, not elsewhere classified	0.005	0.995	0.000
Q43.8 Other specified congenital malformations of intestine	0.005	0.995	0.000
Q27.3 Peripheral arteriovenous malformation	0.005	0.995	0.000
Q83.9 Congenital malformation of breast, unspecified	0.005	0.995	0.000
Q83.2 Absent nipple	0.005	0.995	0.000
Q83.0 Congenital absence of breast with absent nipple	0.005	0.995	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.005	0.995	0.000
Q75 Other congenital malformations of skull and face bones	0.005	0.995	0.000
Q73 Reduction defects of unspecified limb	0.005	0.995	0.000
Q72 Reduction defects of lower limb	0.005	0.995	0.000
Q71 Reduction defects of upper limb	0.005	0.995	0.000
Q70 Syndactyly	0.005	0.995	0.000
Q69 Polydactyly	0.005	0.995	0.000
Q68 Other congenital musculoskeletal deformities	0.005	0.995	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.005	0.995	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.005	0.995	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.005	0.995	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.005	0.995	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.000	0.995	0.004
S93.6 Sprain and strain of other and unspecified parts of foot	0.005	0.995	0.000
Q25.0 Patent ductus arteriosus	0.005	0.995	0.000
R40.0 Somnolence	0.000	0.995	0.005
S93.0 Dislocation of ankle joint	0.005	0.995	0.000
R40.1 Stupor	0.000	0.995	0.005
S99.8 Other specified injuries of ankle and foot	0.004	0.995	0.000
Q43.3 Congenital malformations of intestinal fixation	0.004	0.995	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.004	0.995	0.000
Q39.8 Other congenital malformations of oesophagus	0.004	0.995	0.000
Q39.5 Congenital dilatation of oesophagus	0.004	0.995	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.004	0.995	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.004	0.995	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.004	0.995	0.000
Q39.0 Atresia of oesophagus without fistula	0.004	0.995	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.004	0.995	0.000
S92.1 Fracture of talus	0.004	0.995	0.000
Q21 Congenital malformations of cardiac septa	0.004	0.995	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.004	0.995	0.000
Q25.3 Stenosis of aorta	0.004	0.996	0.000
Q39.4 Oesophageal web	0.004	0.996	0.000
Q78.0 Osteogenesis imperfecta	0.004	0.996	0.000
S92.9 Fracture of foot, unspecified	0.004	0.996	0.000
Q50-Q56 Congenital malformations of genital organs	0.004	0.996	0.000
R45 Symptoms and signs involving emotional state	0.000	0.996	0.004
N41 Inflammatory diseases of prostate	0.000	0.996	0.004
Q00-Q07 Congenital malformations of the nervous system	0.004	0.996	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.004	0.996	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.004	0.996	0.000
Q23.4 Hypoplastic left heart syndrome	0.004	0.996	0.000
Q23.3 Congenital mitral insufficiency	0.004	0.996	0.000
Q23.2 Congenital mitral stenosis	0.004	0.996	0.000
Z29 Need for other prophylactic measures	0.000	0.996	0.004
M46.4 Discitis, unspecified	0.004	0.996	0.000
S93.4 Sprain and strain of ankle	0.004	0.996	0.000
S93.5 Sprain and strain of toe(s)	0.004	0.996	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.004	0.996	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.004	0.996	0.000
Z29.8 Other specified prophylactic measures	0.000	0.996	0.004
Q17 Other congenital malformations of ear	0.004	0.996	0.000
Q24.0 Dextrocardia	0.004	0.996	0.000
S99.7 Multiple injuries of ankle and foot	0.004	0.996	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.004	0.996	0.000
Q25.4 Other congenital malformations of aorta	0.004	0.996	0.000
Q43.7 Persistent cloaca	0.004	0.996	0.000
Q43.6 Congenital fistula of rectum and anus	0.004	0.996	0.000
Q43.5 Ectopic anus	0.004	0.996	0.000
Q43.4 Duplication of intestine	0.004	0.996	0.000
Q43.2 Other congenital functional disorders of colon	0.004	0.996	0.000
Q43.1 Hirschsprung's disease	0.004	0.996	0.000
S97.1 Crushing injury of toe(s)	0.004	0.996	0.000
S97.0 Crushing injury of ankle	0.004	0.996	0.000
Q23.0 Congenital stenosis of aortic valve	0.004	0.996	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.004	0.996	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.004	0.996	0.000
S99.9 Unspecified injury of ankle and foot	0.004	0.996	0.000
Q27.4 Congenital phlebectasia	0.004	0.996	0.000
Q27.2 Other congenital malformations of renal artery	0.004	0.996	0.000
Q27.1 Congenital renal artery stenosis	0.004	0.996	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.004	0.996	0.000
S92.4 Fracture of great toe	0.004	0.996	0.000
Q45.8 Other specified congenital malformations of digestive system	0.004	0.996	0.000
Q76 Congenital malformations of spine and bony thorax	0.004	0.996	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.004	0.996	0.000
Q25.8 Other congenital malformations of great arteries	0.004	0.996	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.004	0.996	0.000
Q25.6 Stenosis of pulmonary artery	0.004	0.996	0.000
Q25.5 Atresia of pulmonary artery	0.004	0.996	0.000
Q25.2 Atresia of aorta	0.004	0.996	0.000
S93.1 Dislocation of toe(s)	0.004	0.996	0.000
Q74 Other congenital malformations of limb(s)	0.004	0.996	0.000
B34.9 Viral infection, unspecified	0.000	0.996	0.004
Q82.8 Other specified congenital malformations of skin	0.004	0.996	0.000
Q67.8 Other congenital deformities of chest	0.004	0.996	0.000
Q67.7 Pectus carinatum	0.004	0.996	0.000
Q67.6 Pectus excavatum	0.004	0.996	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.004	0.996	0.000
Q67.3 Plagiocephaly	0.004	0.996	0.000
Q67.2 Dolichocephaly	0.004	0.996	0.000
Q67.1 Compression facies	0.004	0.996	0.000
Q67.0 Facial asymmetry	0.004	0.996	0.000
R46.0 Very low level of personal hygiene	0.000	0.996	0.004
Q14 Congenital malformations of posterior segment of eye	0.004	0.996	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.004	0.996	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.004	0.996	0.000
Q45.2 Congenital pancreatic cyst	0.004	0.996	0.000
Q45.1 Annular pancreas	0.004	0.996	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.004	0.996	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.004	0.996	0.000
S94.8 Injury of other nerves at ankle and foot level	0.004	0.996	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.004	0.996	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.004	0.996	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.004	0.996	0.000
S94.1 Injury of medial plantar nerve	0.004	0.996	0.000
S94.0 Injury of lateral plantar nerve	0.004	0.996	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.004	0.996	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.004	0.996	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.004	0.996	0.000
S95.2 Injury of dorsal vein of foot	0.004	0.996	0.000
S95.1 Injury of plantar artery of foot	0.004	0.996	0.000
S95.0 Injury of dorsal artery of foot	0.004	0.996	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.004	0.996	0.000
S98.3 Traumatic amputation of other parts of foot	0.004	0.996	0.000
S98.2 Traumatic amputation of two or more toes	0.004	0.996	0.000
S98.1 Traumatic amputation of one toe	0.004	0.996	0.000
S98.0 Traumatic amputation of foot at ankle level	0.004	0.996	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.004	0.996	0.000
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.000	0.996	0.004
R46.6 Undue concern and preoccupation with stressful events	0.000	0.996	0.004
R46.5 Suspiciousness and marked evasiveness	0.000	0.996	0.004
R46.3 Overactivity	0.000	0.996	0.004
R46.1 Bizarre personal appearance	0.000	0.996	0.004
Q24.9 Congenital malformation of the heart, unspecified	0.004	0.996	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.004	0.996	0.000
Q89.3 Situs inversus	0.004	0.996	0.000
Q85 Phakomatoses, not elsewhere classified	0.004	0.996	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.004	0.996	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.004	0.996	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.004	0.996	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.004	0.996	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.004	0.996	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.004	0.996	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.004	0.996	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.004	0.996	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.004	0.996	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.004	0.996	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.004	0.996	0.000
Q82.5 Congenital nonneoplastic naevus	0.004	0.996	0.000
S92.2 Fracture of other tarsal bone(s)	0.004	0.996	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.004	0.996	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.004	0.996	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.004	0.996	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.004	0.996	0.000
Q20.6 Isomerism of atrial appendages	0.004	0.996	0.000
Q20.5 Discordant atrioventricular connexion	0.004	0.996	0.000
Q20.4 Double inlet ventricle	0.004	0.996	0.000
Q20.3 Discordant ventriculoarterial connexion	0.004	0.996	0.000
Q20.2 Double outlet left ventricle	0.004	0.996	0.000
Q20.1 Double outlet right ventricle	0.004	0.996	0.000
Q20.0 Common arterial trunk	0.004	0.996	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.004	0.996	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.004	0.996	0.000
Q22.6 Hypoplastic right heart syndrome	0.004	0.996	0.000
Q22.5 Ebstein's anomaly	0.004	0.996	0.000
Q22.4 Congenital tricuspid stenosis	0.004	0.996	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.004	0.996	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.004	0.996	0.000
Q22.1 Congenital pulmonary valve stenosis	0.004	0.996	0.000
Q22.0 Pulmonary valve atresia	0.004	0.996	0.000
Q24.6 Congenital heart block	0.004	0.996	0.000
Q24.4 Congenital subaortic stenosis	0.004	0.996	0.000
Q24.3 Pulmonary infundibular stenosis	0.004	0.996	0.000
Q24.2 Cor triatriatum	0.004	0.996	0.000
Q24.1 Levocardia	0.004	0.996	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.004	0.996	0.000
Q26.8 Other congenital malformations of great veins	0.004	0.996	0.000
Q26.6 Portal vein-hepatic artery fistula	0.004	0.996	0.000
Q26.5 Anomalous portal venous connexion	0.004	0.996	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.004	0.996	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.004	0.996	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.004	0.996	0.000
Q26.1 Persistent left superior vena cava	0.004	0.996	0.000
Q26.0 Congenital stenosis of vena cava	0.004	0.996	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.004	0.996	0.000
Q78.8 Other specified osteochondrodysplasias	0.004	0.996	0.000
Q78.6 Multiple congenital exostoses	0.004	0.996	0.000
Q78.5 Metaphyseal dysplasia	0.004	0.996	0.000
Q78.4 Enchondromatosis	0.004	0.996	0.000
Q78.3 Progressive diaphyseal dysplasia	0.004	0.996	0.000
Q78.2 Osteopetrosis	0.004	0.996	0.000
Q78.1 Polyostotic fibrous dysplasia	0.004	0.996	0.000
R46.4 Slowness and poor responsiveness	0.000	0.996	0.004
Q83.1 Accessory breast	0.004	0.996	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.004	0.996	0.000
Q15 Other congenital malformations of eye	0.004	0.996	0.000
Q13 Congenital malformations of anterior segment of eye	0.004	0.996	0.000
Q82.9 Congenital malformation of skin, unspecified	0.004	0.996	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.004	0.996	0.000
Q82.3 Incontinentia pigmenti	0.004	0.996	0.000
Q82.1 Xeroderma pigmentosum	0.004	0.996	0.000
Q82.0 Hereditary lymphoedema	0.004	0.996	0.000
T40.2 Other opioids	0.000	0.996	0.004
M48.5 Collapsed vertebra, not elsewhere classified	0.004	0.996	0.000
Q80.9 Congenital ichthyosis, unspecified	0.004	0.996	0.000
Q80.8 Other congenital ichthyosis	0.004	0.996	0.000
Q80.4 Harlequin foetus	0.004	0.996	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.004	0.996	0.000
Q80.2 Lamellar ichthyosis	0.004	0.996	0.000
Q80.1 X-linked ichthyosis	0.004	0.996	0.000
Q80.0 Ichthyosis vulgaris	0.004	0.996	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.004	0.996	0.000
Q81.8 Other epidermolysis bullosa	0.004	0.996	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.004	0.996	0.000
Q81.1 Epidermolysis bullosa letalis	0.004	0.996	0.000
Q81.0 Epidermolysis bullosa simplex	0.004	0.996	0.000
Q84.9 Congenital malformation of integument, unspecified	0.004	0.996	0.000
Q84.8 Other specified congenital malformations of integument	0.004	0.996	0.000
Q84.6 Other congenital malformations of nails	0.004	0.996	0.000
Q84.5 Enlarged and hypertrophic nails	0.004	0.996	0.000
Q84.4 Congenital leukonychia	0.004	0.996	0.000
Q84.3 Anonychia	0.004	0.996	0.000
Q84.2 Other congenital malformations of hair	0.004	0.996	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.004	0.996	0.000
Q84.0 Congenital alopecia	0.004	0.996	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.004	0.996	0.000
Q86.2 Dysmorphism due to warfarin	0.004	0.996	0.000
Q86.1 Foetal hydantoin syndrome	0.004	0.996	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.004	0.996	0.000
Q34 Other congenital malformations of respiratory system	0.004	0.996	0.000
Q33 Congenital malformations of lung	0.004	0.996	0.000
Q32 Congenital malformations of trachea and bronchus	0.004	0.996	0.000
Q31 Congenital malformations of larynx	0.004	0.996	0.000
Q30 Congenital malformations of nose	0.004	0.996	0.000
Q36 Cleft lip	0.004	0.996	0.000
Q35 Cleft palate	0.004	0.996	0.000
Q65 Congenital deformities of hip	0.004	0.996	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.004	0.996	0.000
Q24.5 Malformation of coronary vessels	0.004	0.996	0.000
Q43.0 Meckel's diverticulum	0.004	0.996	0.000
Q37 Cleft palate with cleft lip	0.004	0.996	0.000
S92.7 Multiple fractures of foot	0.004	0.996	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.004	0.996	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.004	0.996	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.004	0.996	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.004	0.996	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.004	0.996	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.004	0.996	0.000
Q90 Down's syndrome	0.004	0.996	0.000
Q17.5 Prominent ear	0.004	0.996	0.000
R44.0 Auditory hallucinations	0.000	0.996	0.004
O64 Obstructed labour due to malposition and malpresentation of foetus	0.000	0.996	0.004
S92.3 Fracture of metatarsal bone	0.004	0.996	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.004	0.996	0.000
Q11.1 Other anophthalmos	0.004	0.996	0.000
S92.5 Fracture of other toe	0.004	0.996	0.000
Q60-Q64 Congenital malformations of the urinary system	0.004	0.996	0.000
Q21.3 Tetralogy of Fallot	0.004	0.996	0.000
Q76.5 Cervical rib	0.004	0.996	0.000
Q89.9 Congenital malformation, unspecified	0.004	0.996	0.000
Q89.8 Other specified congenital malformations	0.004	0.996	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.004	0.996	0.000
Q89.4 Conjoined twins	0.004	0.996	0.000
Q89.1 Congenital malformations of adrenal gland	0.004	0.996	0.000
Q89.0 Congenital malformations of spleen	0.004	0.996	0.000
Q55 Other congenital malformations of male genital organs	0.004	0.996	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.004	0.996	0.000
Q24.8 Other specified congenital malformations of heart	0.004	0.996	0.000
Q03 Congenital hydrocephalus	0.004	0.996	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.003	0.996	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.003	0.996	0.000
Q68.4 Congenital bowing of tibia and fibula	0.003	0.996	0.000
Q68.3 Congenital bowing of femur	0.003	0.996	0.000
Q68.2 Congenital deformity of knee	0.003	0.996	0.000
Q68.1 Congenital deformity of hand	0.003	0.996	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.003	0.996	0.000
Q69.9 Polydactyly, unspecified	0.003	0.996	0.000
Q69.2 Accessory toe(s)	0.003	0.996	0.000
Q69.1 Accessory thumb(s)	0.003	0.996	0.000
Q69.0 Accessory finger(s)	0.003	0.996	0.000
Q70.9 Syndactyly, unspecified	0.003	0.996	0.000
Q70.4 Polysyndactyly	0.003	0.996	0.000
Q70.3 Webbed toes	0.003	0.996	0.000
Q70.2 Fused toes	0.003	0.996	0.000
Q70.1 Webbed fingers	0.003	0.996	0.000
Q70.0 Fused fingers	0.003	0.996	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.003	0.996	0.000
Q71.8 Other reduction defects of upper limb(s)	0.003	0.996	0.000
Q71.6 Lobster-claw hand	0.003	0.996	0.000
Q71.5 Longitudinal reduction defect of ulna	0.003	0.996	0.000
Q71.4 Longitudinal reduction defect of radius	0.003	0.996	0.000
Q71.3 Congenital absence of hand and finger(s)	0.003	0.996	0.000
Q71.2 Congenital absence of both forearm and hand	0.003	0.996	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.003	0.996	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.003	0.996	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.003	0.996	0.000
Q72.8 Other reduction defects of lower limb(s)	0.003	0.996	0.000
Q72.7 Split foot	0.003	0.996	0.000
Q72.6 Longitudinal reduction defect of fibula	0.003	0.996	0.000
Q72.5 Longitudinal reduction defect of tibia	0.003	0.996	0.000
Q72.4 Longitudinal reduction defect of femur	0.003	0.996	0.000
Q72.3 Congenital absence of foot and toe(s)	0.003	0.996	0.000
Q72.2 Congenital absence of both lower leg and foot	0.003	0.996	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.003	0.996	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.003	0.996	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.003	0.996	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.003	0.996	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.003	0.996	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.003	0.996	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.003	0.996	0.000
Q75.5 Oculomandibular dysostosis	0.003	0.996	0.000
Q75.4 Mandibulofacial dysostosis	0.003	0.996	0.000
Q75.3 Macrocephaly	0.003	0.996	0.000
Q75.2 Hypertelorism	0.003	0.996	0.000
Q75.1 Craniofacial dysostosis	0.003	0.996	0.000
Q75.0 Craniosynostosis	0.003	0.996	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.003	0.996	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.996	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.003	0.996	0.000
Q77.6 Chondroectodermal dysplasia	0.003	0.996	0.000
Q77.5 Diastrophic dysplasia	0.003	0.996	0.000
Q77.4 Achondroplasia	0.003	0.996	0.000
Q77.3 Chondrodysplasia punctata	0.003	0.996	0.000
Q77.2 Short rib syndrome	0.003	0.996	0.000
Q77.1 Thanatophoric short stature	0.003	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations