TreeWAS – Variant ID: rs12157904

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter II Neoplasms	0.894	0.106
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.887	0.113
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.879	0.121
# Top node	0.876	0.124
Chapter XII Diseases of the skin and subcutaneous tissue	0.873	0.127
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.866	0.134
C79 Secondary malignant neoplasm of other sites	0.864	0.136
L60-L75 Disorders of skin appendages	0.851	0.149
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.845	0.155
L72 Follicular cysts of skin and subcutaneous tissue	0.838	0.162
L40-L45 Papulosquamous disorders	0.837	0.163
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.832	0.168
C78.0 Secondary malignant neoplasm of lung	0.815	0.185
Chapter VIII Diseases of the ear and mastoid process	0.813	0.187
L72.0 Epidermal cyst	0.810	0.190
L40 Psoriasis	0.808	0.192
Chapter XX External causes of morbidity and mortality	0.805	0.195
D10-D36 Benign neoplasms	0.798	0.202
S60-S69 Injuries to the wrist and hand	0.795	0.205
C15-C26 Malignant neoplasms of digestive organs	0.789	0.211
C34 Malignant neoplasm of bronchus and lung	0.788	0.212
L40.9 Psoriasis, unspecified	0.788	0.212
H65-H75 Diseases of middle ear and mastoid	0.787	0.213
Chapter VII Diseases of the eye and adnexa	0.787	0.213
T90 Sequelae of injuries of head	0.783	0.217
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.780	0.220
D00-D09 In situ neoplasms	0.772	0.228
C79.7 Secondary malignant neoplasm of adrenal gland	0.769	0.231
T93 Sequelae of injuries of lower limb	0.765	0.235
T66-T78 Other and unspecified effects of external causes	0.761	0.238
Chapter I Certain infectious and parasitic diseases	0.756	0.244
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.755	0.245
H40-H42 Glaucoma	0.750	0.250
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.741	0.259
D37-D48 Neoplasms of uncertain or unknown behaviour	0.741	0.259
L50-L54 Urticaria and erythema	0.738	0.262
C34.9 Bronchus or lung, unspecified	0.736	0.264
C64-C68 Malignant neoplasms of urinary tract	0.732	0.268
C79.8 Secondary malignant neoplasm of other specified sites	0.731	0.269
D18 Haemangioma and lymphangioma, any site	0.729	0.271
T98 Sequelae of other and unspecified effects of external causes	0.728	0.272
C78.7 Secondary malignant neoplasm of liver	0.725	0.275
T90.2 Sequelae of fracture of skull and facial bones	0.724	0.276
H40 Glaucoma	0.723	0.277
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.720	0.280
C79.2 Secondary malignant neoplasm of skin	0.718	0.282
T92 Sequelae of injuries of upper limb	0.717	0.283
S80-S89 Injuries to the knee and lower leg	0.717	0.283
H72 Perforation of tympanic membrane	0.716	0.284
S90-S99 Injuries to the ankle and foot	0.713	0.287
D23 Other benign neoplasms of skin	0.705	0.295
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.704	0.296
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.702	0.298
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.698	0.302
A00-A09 Intestinal infectious diseases	0.697	0.303
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.694	0.306
S67 Crushing injury of wrist and hand	0.693	0.307
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.688	0.312
H30-H36 Disorders of choroid and retina	0.688	0.312
C50-C50 Malignant neoplasm of breast	0.685	0.315
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.683	0.317
H74 Other disorders of middle ear and mastoid	0.683	0.317
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.682	0.318
D18.0 Haemangioma, any site	0.681	0.319
H40.1 Primary open-angle glaucoma	0.680	0.320
T78 Adverse effects, not elsewhere classified	0.678	0.322
C79.9 Secondary malignant neoplasm, unspecified site	0.677	0.323
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.676	0.324
D35 Benign neoplasm of other and unspecified endocrine glands	0.675	0.325
C20 Malignant neoplasm of rectum	0.675	0.325
T79-T79 Certain early complications of trauma	0.674	0.326
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.673	0.327
T91 Sequelae of injuries of neck and trunk	0.672	0.328
S40-S49 Injuries to the shoulder and upper arm	0.671	0.329
C19 Malignant neoplasm of rectosigmoid junction	0.664	0.336
D27 Benign neoplasm of ovary	0.663	0.337
C18 Malignant neoplasm of colon	0.662	0.338
Y83.8 Other surgical procedures	0.659	0.341
D24 Benign neoplasm of breast	0.655	0.345
H40.0 Glaucoma suspect	0.654	0.346
S64 Injury of nerves at wrist and hand level	0.653	0.347
T15-T19 Effects of foreign body entering through natural orifice	0.652	0.348
H66 Suppurative and unspecified otitis media	0.648	0.352
D09 Carcinoma in situ of other and unspecified sites	0.648	0.352
A08 Viral and other specified intestinal infections	0.646	0.354
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.644	0.356
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.642	0.358
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.641	0.359
C40-C41 Malignant neoplasms of bone and articular cartilage	0.641	0.359
D05 Carcinoma in situ of breast	0.641	0.359
S68 Traumatic amputation of wrist and hand	0.639	0.361
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.638	0.362
T85 Complications of other internal prosthetic devices, implants and grafts	0.637	0.363
Chapter XXII Codes for special purposes	0.637	0.363
S70-S79 Injuries to the hip and thigh	0.637	0.363
C76 Malignant neoplasm of other and ill-defined sites	0.636	0.364
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.635	0.365
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.633	0.367
C34.1 Upper lobe, bronchus or lung	0.632	0.368
T93.9 Sequelae of unspecified injury of lower limb	0.631	0.369
T33-T35 Frostbite	0.630	0.370
T26-T28 Burns and corrosions confined to eye and internal organs	0.630	0.370
T20-T25 Burns and corrosions of external body surface, specified by site	0.630	0.370
T00-T07 Injuries involving multiple body regions	0.630	0.370
S10-S19 Injuries to the neck	0.630	0.370
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.629	0.371
Chapter XVI Certain conditions originating in the perinatal period	0.628	0.371
D33 Benign neoplasm of brain and other parts of central nervous system	0.627	0.373
D26 Other benign neoplasms of uterus	0.627	0.373
L10-L14 Bullous disorders	0.626	0.374
C80 Malignant neoplasm without specification of site	0.625	0.375
A30-A49 Other bacterial diseases	0.624	0.376
S00-S09 Injuries to the head	0.624	0.376
L43 Lichen planus	0.623	0.377
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.622	0.378
T95 Sequelae of burns, corrosions and frostbite	0.621	0.379
T94 Sequelae of injuries involving multiple and unspecified body regions	0.621	0.379
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.621	0.379
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.621	0.379
H72.9 Perforation of tympanic membrane, unspecified	0.621	0.379
T86 Failure and rejection of transplanted organs and tissues	0.620	0.380
C79.6 Secondary malignant neoplasm of ovary	0.620	0.380
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.620	0.380
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.620	0.380
D23.1 Skin of eyelid, including canthus	0.620	0.380
S67.0 Crushing injury of thumb and other finger(s)	0.619	0.381
L73 Other follicular disorders	0.618	0.382
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.617	0.383
D13.1 Stomach	0.617	0.383
S50-S59 Injuries to the elbow and forearm	0.616	0.384
S66 Injury of muscle and tendon at wrist and hand level	0.615	0.385
V40-V49 Car occupant injured in transport accident	0.615	0.385
C51-C58 Malignant neoplasms of female genital organs	0.614	0.386
L00-L08 Infections of the skin and subcutaneous tissue	0.611	0.389
L75 Apocrine sweat disorders	0.610	0.390
L74 Eccrine sweat disorders	0.610	0.390
L71 Rosacea	0.610	0.390
L70 Acne	0.610	0.390
L68 Hypertrichosis	0.610	0.390
L67 Hair colour and hair shaft abnormalities	0.610	0.390
L66 Cicatricial alopecia [scarring hair loss]	0.610	0.390
L65 Other nonscarring hair loss	0.610	0.390
L64 Androgenic alopecia	0.610	0.390
L63 Alopecia areata	0.610	0.390
L62 Nail disorders in diseases classified elsewhere	0.610	0.390
A08.4 Viral intestinal infection, unspecified	0.610	0.390
D35.1 Parathyroid gland	0.609	0.390
H73 Other disorders of tympanic membrane	0.609	0.391
D30 Benign neoplasm of urinary organs	0.608	0.392
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.606	0.394
C78.4 Secondary malignant neoplasm of small intestine	0.606	0.394
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.606	0.394
C78.1 Secondary malignant neoplasm of mediastinum	0.606	0.394
L50 Urticaria	0.606	0.394
S91 Open wound of ankle and foot	0.606	0.394
X60-X84 Intentional self-harm	0.606	0.394
L72.2 Steatocystoma multiplex	0.601	0.399
H35 Other retinal disorders	0.601	0.399
L44 Other papulosquamous disorders	0.600	0.400
L41 Parapsoriasis	0.600	0.400
L45 Papulosquamous disorders in diseases classified elsewhere	0.600	0.400
L42 Pityriasis rosea	0.600	0.400
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.599	0.400
C18.4 Transverse colon	0.599	0.401
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.597	0.403
C38 Malignant neoplasm of heart, mediastinum and pleura	0.597	0.403
C32 Malignant neoplasm of larynx	0.597	0.403
C31 Malignant neoplasm of accessory sinuses	0.597	0.403
C30 Malignant neoplasm of nasal cavity and middle ear	0.597	0.403
C37 Malignant neoplasm of thymus	0.597	0.403
C33 Malignant neoplasm of trachea	0.597	0.403
H71 Cholesteatoma of middle ear	0.593	0.407
T78.3 Angioneurotic oedema	0.592	0.408
D03 Melanoma in situ	0.591	0.409
T93.2 Sequelae of other fractures of lower limb	0.590	0.409
H60-H62 Diseases of external ear	0.589	0.411
Y83.3 Surgical operation with formation of external stoma	0.589	0.411
D36 Benign neoplasm of other and unspecified sites	0.588	0.411
L72.8 Other follicular cysts of skin and subcutaneous tissue	0.587	0.413
C34.3 Lower lobe, bronchus or lung	0.587	0.413
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.586	0.414
L53 Other erythematous conditions	0.586	0.414
D23.7 Skin of lower limb, including hip	0.586	0.414
Y43 Primarily systemic agents	0.585	0.415
D04 Carcinoma in situ of skin	0.584	0.416
Y60-Y69 Misadventures to patients during surgical and medical care	0.584	0.416
C26 Malignant neoplasm of other and ill-defined digestive organs	0.583	0.416
D21 Other benign neoplasms of connective and other soft tissue	0.583	0.416
S82 Fracture of lower leg, including ankle	0.583	0.417
H10-H13 Disorders of conjunctiva	0.583	0.417
Y83.4 Other reconstructive surgery	0.583	0.417
D46 Myelodysplastic syndromes	0.582	0.417
H72.0 Central perforation of tympanic membrane	0.581	0.418
D23.9 Skin, unspecified	0.581	0.418
B15-B19 Viral hepatitis	0.579	0.421
L40.8 Other psoriasis	0.579	0.421
L40.4 Guttate psoriasis	0.579	0.421
L40.3 Pustulosis palmaris et plantaris	0.579	0.421
L40.2 Acrodermatitis continua	0.579	0.421
L40.1 Generalised pustular psoriasis	0.579	0.421
L40.0 Psoriasis vulgaris	0.579	0.421
D37.7 Other digestive organs	0.579	0.421
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.578	0.422
C66 Malignant neoplasm of ureter	0.578	0.422
Y83.0 Surgical operation with transplant of whole organ	0.578	0.422
L40.5 Arthropathic psoriasis	0.578	0.422
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.577	0.423
Y35-Y36 Legal intervention and operations of war	0.577	0.423
Y10-Y34 Event of undetermined intent	0.577	0.423
Y00-Y09 Assault	0.577	0.423
X85-X99 Assault	0.577	0.423
X58-X59 Accidental exposure to other and unspecified factors	0.577	0.423
X50-X57 Overexertion, travel and privation	0.577	0.423
X40-X49 Accidental poisoning by and exposure to noxious substances	0.577	0.423
X30-X39 Exposure to forces of nature	0.577	0.423
X20-X29 Contact with venomous animals and plants	0.577	0.423
X10-X19 Contact with heat and hot substances	0.577	0.423
X00-X09 Exposure to smoke, fire and flames	0.577	0.423
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.577	0.423
W75-W84 Other accidental threats to breathing	0.577	0.423
W65-W74 Accidental drowning and submersion	0.577	0.423
W50-W64 Exposure to animate mechanical forces	0.577	0.423
V98-V99 Other and unspecified transport accidents	0.577	0.423
V95-V97 Air and space transport accidents	0.577	0.423
V90-V94 Water transport accidents	0.577	0.423
V80-V89 Other land transport accidents	0.577	0.423
V70-V79 Bus occupant injured in transport accident	0.577	0.423
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.577	0.423
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.577	0.423
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.577	0.423
V01-V09 Pedestrian injured in transport accident	0.577	0.423
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.577	0.423
C34.0 Main bronchus	0.577	0.423
D10 Benign neoplasm of mouth and pharynx	0.576	0.424
L20-L30 Dermatitis and eczema	0.574	0.426
V10-V19 Pedal cyclist injured in transport accident	0.573	0.427
D31 Benign neoplasm of eye and adnexa	0.572	0.428
D29 Benign neoplasm of male genital organs	0.572	0.428
D28 Benign neoplasm of other and unspecified female genital organs	0.572	0.428
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.572	0.428
D19 Benign neoplasm of mesothelial tissue	0.572	0.428
D16 Benign neoplasm of bone and articular cartilage	0.572	0.428
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.572	0.428
D14 Benign neoplasm of middle ear and respiratory system	0.572	0.428
D34 Benign neoplasm of thyroid gland	0.572	0.428
S69 Other and unspecified injuries of wrist and hand	0.570	0.430
S65 Injury of blood vessels at wrist and hand level	0.570	0.430
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.570	0.430
S60 Superficial injury of wrist and hand	0.570	0.430
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.570	0.430
C67 Malignant neoplasm of bladder	0.569	0.431
S62 Fracture at wrist and hand level	0.568	0.432
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.566	0.434
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.565	0.435
C21 Malignant neoplasm of anus and anal canal	0.565	0.435
C17 Malignant neoplasm of small intestine	0.565	0.435
C23 Malignant neoplasm of gallbladder	0.565	0.435
C34.8 Overlapping lesion of bronchus and lung	0.565	0.435
C34.2 Middle lobe, bronchus or lung	0.565	0.435
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.564	0.436
H70 Mastoiditis and related conditions	0.564	0.436
H69 Other disorders of Eustachian tube	0.564	0.436
H68 Eustachian salpingitis and obstruction	0.564	0.436
H67 Otitis media in diseases classified elsewhere	0.564	0.436
H46-H48 Disorders of optic nerve and visual pathways	0.564	0.436
A04 Other bacterial intestinal infections	0.563	0.437
T81 Complications of procedures, not elsewhere classified	0.562	0.438
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.562	0.438
H74.9 Disorder of middle ear and mastoid, unspecified	0.562	0.438
T90.9 Sequelae of unspecified injury of head	0.562	0.438
T90.8 Sequelae of other specified injuries of head	0.562	0.438
T90.5 Sequelae of intracranial injury	0.562	0.438
T90.4 Sequelae of injury of eye and orbit	0.562	0.438
T90.3 Sequelae of injury of cranial nerves	0.562	0.438
T90.1 Sequelae of open wound of head	0.562	0.438
T90.0 Sequelae of superficial injury of head	0.562	0.438
L02 Cutaneous abscess, furuncle and carbuncle	0.561	0.439
B35-B49 Mycoses	0.561	0.439
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.560	0.440
W20-W49 Exposure to inanimate mechanical forces	0.560	0.440
D09.0 Bladder	0.559	0.441
Chapter VI Diseases of the nervous system	0.559	0.441
C71 Malignant neoplasm of brain	0.559	0.441
T92.1 Sequelae of fracture of arm	0.558	0.442
S20-S29 Injuries to the thorax	0.557	0.443
H53-H54 Visual disturbances and blindness	0.555	0.445
L57 Skin changes due to chronic exposure to nonionising radiation	0.555	0.445
A50-A64 Infections with a predominantly sexual mode of transmission	0.555	0.445
D02 Carcinoma in situ of middle ear and respiratory system	0.553	0.446
D01 Carcinoma in situ of other and unspecified digestive organs	0.553	0.446
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.553	0.446
H90-H95 Other disorders of ear	0.553	0.447
V20-V29 Motorcycle rider injured in transport accident	0.553	0.447
Q80-Q89 Other congenital malformations	0.552	0.448
H72.8 Other perforations of tympanic membrane	0.551	0.449
C18.7 Sigmoid colon	0.551	0.449
S64.4 Injury of digital nerve of other finger	0.551	0.449
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.550	0.450
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.549	0.451
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.549	0.451
T93.8 Sequelae of other specified injuries of lower limb	0.549	0.451
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.549	0.451
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.549	0.451
T93.4 Sequelae of injury of nerve of lower limb	0.549	0.451
T93.1 Sequelae of fracture of femur	0.549	0.451
T93.0 Sequelae of open wound of lower limb	0.549	0.451
T86.8 Failure and rejection of other transplanted organs and tissues	0.549	0.451
H74.8 Other specified disorders of middle ear and mastoid	0.548	0.452
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.547	0.453
Q60-Q64 Congenital malformations of the urinary system	0.546	0.454
S42 Fracture of shoulder and upper arm	0.546	0.454
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.546	0.454
T75 Effects of other external causes	0.546	0.454
T74 Maltreatment syndromes	0.546	0.454
T73 Effects of other deprivation	0.546	0.454
T70 Effects of air pressure and water pressure	0.546	0.454
T69 Other effects of reduced temperature	0.546	0.454
T67 Effects of heat and light	0.546	0.454
T71 Asphyxiation	0.546	0.454
T68 Hypothermia	0.546	0.454
T66 Unspecified effects of radiation	0.546	0.454
L60 Nail disorders	0.545	0.455
H35.3 Degeneration of macula and posterior pole	0.544	0.456
H40.9 Glaucoma, unspecified	0.544	0.456
T78.4 Allergy, unspecified	0.544	0.456
B99-B99 Other infectious diseases	0.542	0.458
B90-B94 Sequelae of infectious and parasitic diseases	0.542	0.458
B85-B89 Pediculosis, acariasis and other infestations	0.542	0.458
B65-B83 Helminthiases	0.542	0.458
B50-B64 Protozoal diseases	0.542	0.458
B20-B24 Human immunodeficiency virus [HIV] disease	0.542	0.458
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.542	0.458
A80-A89 Viral infections of the central nervous system	0.542	0.458
A75-A79 Rickettsioses	0.542	0.458
A70-A74 Other diseases caused by chlamydiae	0.542	0.458
A65-A69 Other spirochaetal diseases	0.542	0.458
A20-A28 Certain zoonotic bacterial diseases	0.542	0.458
A15-A19 Tuberculosis	0.542	0.458
D37.5 Rectum	0.541	0.458
H55-H59 Other disorders of eye and adnexa	0.538	0.462
H42 Glaucoma in diseases classified elsewhere	0.537	0.462
W00-W19 Falls	0.537	0.463
S00 Superficial injury of head	0.536	0.464
C50 Malignant neoplasm of breast	0.536	0.464
T91.3 Sequelae of injury of spinal cord	0.532	0.467
C64 Malignant neoplasm of kidney, except renal pelvis	0.532	0.468
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.532	0.468
D11 Benign neoplasm of major salivary glands	0.531	0.469
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.531	0.469
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.531	0.469
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.531	0.469
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.531	0.469
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.531	0.469
T17 Foreign body in respiratory tract	0.531	0.469
D37.4 Colon	0.530	0.470
L54 Erythema in diseases classified elsewhere	0.529	0.471
L51 Erythema multiforme	0.529	0.471
L52 Erythema nodosum	0.529	0.471
C16 Malignant neoplasm of stomach	0.529	0.471
Y57 Other and unspecified drugs and medicaments	0.528	0.472
T79 Certain early complications of trauma, not elsewhere classified	0.528	0.472
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.527	0.472
L72.1 Trichilemmal cyst	0.527	0.473
H18 Other disorders of cornea	0.526	0.474
D05.9 Carcinoma in situ of breast, unspecified	0.526	0.474
H66.9 Otitis media, unspecified	0.525	0.475
C68 Malignant neoplasm of other and unspecified urinary organs	0.524	0.475
C65 Malignant neoplasm of renal pelvis	0.524	0.475
D18.1 Lymphangioma, any site	0.523	0.477
D23.2 Skin of ear and external auricular canal	0.523	0.477
T98.2 Sequelae of certain early complications of trauma	0.522	0.478
T98.1 Sequelae of other and unspecified effects of external causes	0.522	0.478
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.522	0.478
Y52 Agents primarily affecting the cardiovascular system	0.522	0.478
A49 Bacterial infection of unspecified site	0.521	0.479
Q50-Q56 Congenital malformations of genital organs	0.521	0.479
H40.8 Other glaucoma	0.518	0.481
H40.6 Glaucoma secondary to drugs	0.518	0.481
H40.5 Glaucoma secondary to other eye disorders	0.518	0.481
H40.4 Glaucoma secondary to eye inflammation	0.518	0.481
H40.3 Glaucoma secondary to eye trauma	0.518	0.481
D07 Carcinoma in situ of other and unspecified genital organs	0.517	0.482
T92.2 Sequelae of fracture at wrist and hand level	0.517	0.483
C45 Mesothelioma	0.517	0.483
T87 Complications peculiar to reattachment and amputation	0.516	0.483
T80 Complications following infusion, transfusion and therapeutic injection	0.516	0.483
Y40 Systemic antibiotics	0.516	0.484
T92.9 Sequelae of unspecified injury of upper limb	0.514	0.486
T92.8 Sequelae of other specified injuries of upper limb	0.514	0.486
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.514	0.486
T92.4 Sequelae of injury of nerve of upper limb	0.514	0.486
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.514	0.486
T92.0 Sequelae of open wound of upper limb	0.514	0.486
S89 Other and unspecified injuries of lower leg	0.514	0.486
S88 Traumatic amputation of lower leg	0.514	0.486
S87 Crushing injury of lower leg	0.514	0.486
S86 Injury of muscle and tendon at lower leg level	0.514	0.486
S85 Injury of blood vessels at lower leg level	0.514	0.486
S84 Injury of nerves at lower leg level	0.514	0.486
H72.2 Other marginal perforations of tympanic membrane	0.513	0.487
H72.1 Attic perforation of tympanic membrane	0.513	0.487
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.513	0.487
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.513	0.487
S99 Other and unspecified injuries of ankle and foot	0.511	0.488
S98 Traumatic amputation of ankle and foot	0.511	0.488
S97 Crushing injury of ankle and foot	0.511	0.488
S96 Injury of muscle and tendon at ankle and foot level	0.511	0.488
S95 Injury of blood vessels at ankle and foot level	0.511	0.488
S94 Injury of nerves at ankle and foot level	0.511	0.488
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.511	0.488
S90 Superficial injury of ankle and foot	0.511	0.488
H36 Retinal disorders in diseases classified elsewhere	0.511	0.489
H74.4 Polyp of middle ear	0.511	0.489
Q00-Q07 Congenital malformations of the nervous system	0.510	0.490
C02 Malignant neoplasm of other and unspecified parts of tongue	0.508	0.492
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.508	0.492
C67.5 Bladder neck	0.507	0.493
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.507	0.493
D23.0 Skin of lip	0.505	0.494
D33.3 Cranial nerves	0.505	0.495
C49 Malignant neoplasm of other connective and soft tissue	0.505	0.495
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.505	0.495
C46 Kaposi's sarcoma	0.505	0.495
H33 Retinal detachments and breaks	0.505	0.495
D26.0 Cervix uteri	0.505	0.495
C78.2 Secondary malignant neoplasm of pleura	0.504	0.496
Y43.3 Other antineoplastic drugs	0.504	0.496
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.503	0.496
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.503	0.496
Q38-Q45 Other congenital malformations of the digestive system	0.503	0.496
Q35-Q37 Cleft lip and cleft palate	0.503	0.496
Q30-Q34 Congenital malformations of the respiratory system	0.503	0.496
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.503	0.496
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.503	0.497
D13.2 Duodenum	0.503	0.497
S81 Open wound of lower leg	0.501	0.498
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.501	0.499
C70 Malignant neoplasm of meninges	0.501	0.499
C69 Malignant neoplasm of eye and adnexa	0.501	0.499
H34 Retinal vascular occlusions	0.501	0.499
H66.3 Other chronic suppurative otitis media	0.500	0.500
A07 Other protozoal intestinal diseases	0.500	0.500
A06 Amoebiasis	0.500	0.500
A05 Other bacterial foodborne intoxications	0.500	0.500
A03 Shigellosis	0.500	0.500
A02 Other Salmonella infections	0.500	0.500
A01 Typhoid and paratyphoid fevers	0.500	0.500
A00 Cholera	0.500	0.500
C09 Malignant neoplasm of tonsil	0.498	0.502
T81.8 Other complications of procedures, not elsewhere classified	0.498	0.502
D13.9 Ill-defined sites within the digestive system	0.497	0.502
D13.7 Endocrine pancreas	0.497	0.502
D13.6 Pancreas	0.497	0.502
D13.5 Extrahepatic bile ducts	0.497	0.502
D13.4 Liver	0.497	0.502
D13.3 Other and unspecified parts of small intestine	0.497	0.502
D13.0 Oesophagus	0.497	0.502
S02 Fracture of skull and facial bones	0.497	0.503
Y44 Agents primarily affecting blood constituents	0.497	0.503
S82.2 Fracture of shaft of tibia	0.497	0.503
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.497	0.503
D23.4 Skin of scalp and neck	0.496	0.504
H65 Nonsuppurative otitis media	0.495	0.505
A04.7 Enterocolitis due to Clostridium difficile	0.494	0.505
T85.2 Mechanical complication of intraocular lens	0.494	0.506
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.493	0.507
L58 Radiodermatitis	0.493	0.507
L56 Other acute skin changes due to ultraviolet radiation	0.493	0.507
L55 Sunburn	0.493	0.507
H32 Chorioretinal disorders in diseases classified elsewhere	0.493	0.507
H31 Other disorders of choroid	0.493	0.507
H30 Chorioretinal inflammation	0.493	0.507
S91.1 Open wound of toe(s) without damage to nail	0.493	0.507
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.492	0.508
S49 Other and unspecified injuries of shoulder and upper arm	0.492	0.508
S83.2 Tear of meniscus, current	0.492	0.508
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.491	0.509
S92 Fracture of foot, except ankle	0.490	0.510
B25-B34 Other viral diseases	0.490	0.510
Y83.5 Amputation of limb(s)	0.490	0.510
S91.3 Open wound of other parts of foot	0.490	0.510
H74.3 Other acquired abnormalities of ear ossicles	0.489	0.510
H74.2 Discontinuity and dislocation of ear ossicles	0.489	0.510
H74.1 Adhesive middle ear disease	0.489	0.510
H74.0 Tympanosclerosis	0.489	0.510
Y59 Other and unspecified vaccines and biological substances	0.489	0.511
Y58 Bacterial vaccines	0.489	0.511
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.489	0.511
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.489	0.511
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.489	0.511
Y53 Agents primarily affecting the gastro-intestinal system	0.489	0.511
Y51 Drugs primarily affecting the autonomic nervous system	0.489	0.511
Y50 Central nervous system stimulants, not elsewhere classified	0.489	0.511
Y49 Psychotropic drugs, not elsewhere classified	0.489	0.511
Y48 Anaesthetics and therapeutic gases	0.489	0.511
Y47 Sedatives, hypnotics and antianxiety drugs	0.489	0.511
Y46 Antiepileptics and anti-Parkinsonism drugs	0.489	0.511
Y41 Other systemic anti-infectives and antiparasitics	0.489	0.511
A40 Streptococcal septicaemia	0.487	0.512
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.487	0.513

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations