TreeWAS – Variant ID: rs12190287

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
I21 Acute myocardial infarction	0.000	0.000	1.000
I25.2 Old myocardial infarction	0.000	0.001	0.999
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.003	0.997
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.019	0.981
I20 Angina pectoris	0.000	0.033	0.967
I21.9 Acute myocardial infarction, unspecified	0.000	0.038	0.962
I20.9 Angina pectoris, unspecified	0.000	0.050	0.950
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.059	0.941
I22 Subsequent myocardial infarction	0.000	0.064	0.936
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.119	0.881
I25.5 Ischaemic cardiomyopathy	0.000	0.129	0.871
I21.4 Acute subendocardial myocardial infarction	0.000	0.176	0.824
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.182	0.818
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.195	0.805
I23 Certain current complications following acute myocardial infarction	0.000	0.238	0.762
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.257	0.743
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.273	0.727
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.283	0.717
I20.0 Unstable angina	0.000	0.287	0.713
I20.8 Other forms of angina pectoris	0.000	0.291	0.709
I22.8 Subsequent myocardial infarction of other sites	0.000	0.320	0.679
I24 Other acute ischaemic heart diseases	0.000	0.370	0.630
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.379	0.621
I23.8 Other current complications following acute myocardial infarction	0.000	0.408	0.591
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.445	0.555
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.446	0.554
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.453	0.546
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.453	0.546
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.453	0.546
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.453	0.546
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.453	0.546
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.453	0.546
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.453	0.546
I20.1 Angina pectoris with documented spasm	0.000	0.468	0.532
I25.4 Coronary artery aneurysm	0.000	0.511	0.489
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.570	0.430
I24.1 Dressler's syndrome	0.000	0.592	0.408
I25.3 Aneurysm of heart	0.001	0.632	0.368
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.320	0.680	0.000
J44 Other chronic obstructive pulmonary disease	0.312	0.688	0.000
J47 Bronchiectasis	0.301	0.699	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.299	0.701	0.000
J40-J47 Chronic lower respiratory diseases	0.287	0.713	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.260	0.740	0.000
J42 Unspecified chronic bronchitis	0.256	0.744	0.000
J41 Simple and mucopurulent chronic bronchitis	0.194	0.806	0.000
I24.8 Other forms of acute ischaemic heart disease	0.000	0.818	0.182
N20.1 Calculus of ureter	0.000	0.840	0.160
N20 Calculus of kidney and ureter	0.000	0.842	0.158
J43 Emphysema	0.145	0.855	0.000
N20.0 Calculus of kidney	0.000	0.855	0.145
J40 Bronchitis, not specified as acute or chronic	0.142	0.858	0.000
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.139	0.861	0.000
J41.1 Mucopurulent chronic bronchitis	0.139	0.861	0.000
N20-N23 Urolithiasis	0.000	0.861	0.139
N21 Calculus of lower urinary tract	0.000	0.865	0.135
N20.2 Calculus of kidney with calculus of ureter	0.000	0.867	0.133
J46 Status asthmaticus	0.129	0.871	0.000
J41.0 Simple chronic bronchitis	0.127	0.873	0.000
N21.0 Calculus in bladder	0.000	0.873	0.127
N21.1 Calculus in urethra	0.000	0.875	0.125
J43.2 Centrilobular emphysema	0.124	0.876	0.000
N20.9 Urinary calculus, unspecified	0.000	0.877	0.123
N23 Unspecified renal colic	0.000	0.892	0.108
J43.1 Panlobular emphysema	0.104	0.896	0.000
J43.0 MacLeod's syndrome	0.104	0.896	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.000	0.900	0.100
N21.9 Calculus of lower urinary tract, unspecified	0.000	0.903	0.097
J45 Asthma	0.083	0.917	0.000
J43.8 Other emphysema	0.077	0.923	0.000
N21.8 Other lower urinary tract calculus	0.000	0.927	0.073
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.000	0.928	0.071
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.000	0.928	0.071
J45.8 Mixed asthma	0.061	0.938	0.000
J45.1 Nonallergic asthma	0.050	0.950	0.000
J45.0 Predominantly allergic asthma	0.049	0.951	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.043	0.957	0.000
I10 Essential (primary) hypertension	0.000	0.970	0.030
J43.9 Emphysema, unspecified	0.028	0.972	0.000
N32.8 Other specified disorders of bladder	0.000	0.976	0.024
I50.1 Left ventricular failure	0.000	0.984	0.016
T42.4 Benzodiazepines	0.012	0.988	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.012	0.988	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.010	0.990	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.009	0.991	0.000
I10-I15 Hypertensive diseases	0.000	0.991	0.009
N87 Dysplasia of cervix uteri	0.008	0.992	0.000
N87.1 Moderate cervical dysplasia	0.008	0.992	0.000
K61.3 Ischiorectal abscess	0.000	0.993	0.007
T79.3 Post-traumatic wound infection, not elsewhere classified	0.007	0.993	0.000
Q61.3 Polycystic kidney, unspecified	0.007	0.993	0.000
S22.40 Multiple fractures of ribs (closed)	0.007	0.993	0.000
I11 Hypertensive heart disease	0.000	0.993	0.007
Q61.2 Polycystic kidney, adult type	0.006	0.994	0.000
N64.5 Other signs and symptoms in breast	0.006	0.994	0.000
Q61 Cystic kidney disease	0.006	0.994	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.006	0.994	0.000
I13 Hypertensive heart and renal disease	0.000	0.994	0.006
R26.2 Difficulty in walking, not elsewhere classified	0.000	0.994	0.006
H81.0 Meniere's disease	0.000	0.994	0.006
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.994	0.006
N87.2 Severe cervical dysplasia, not elsewhere classified	0.005	0.994	0.000
N87.0 Mild cervical dysplasia	0.006	0.994	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.005	0.995	0.000
Chapter IX Diseases of the circulatory system	0.000	0.995	0.005
J38.7 Other diseases of larynx	0.005	0.995	0.000
Q61.9 Cystic kidney disease, unspecified	0.005	0.995	0.000
Q61.5 Medullary cystic kidney	0.005	0.995	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.005	0.995	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.995	0.005
Q61.8 Other cystic kidney diseases	0.005	0.995	0.000
Q61.1 Polycystic kidney, infantile type	0.005	0.995	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.005	0.995	0.000
I15 Secondary hypertension	0.000	0.995	0.005
M96.8 Other postprocedural musculoskeletal disorders	0.005	0.995	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.005	0.995	0.000
T42.3 Barbiturates	0.005	0.995	0.000
T42.2 Succinimides and oxazolidinediones	0.005	0.995	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.995	0.004
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.995	0.004
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.995	0.004
Q61.0 Congenital single renal cyst	0.005	0.995	0.000
N64 Other disorders of breast	0.005	0.995	0.000
M79.19 Myalgia (Site unspecified)	0.000	0.995	0.005
O86.0 Infection of obstetric surgical wound	0.004	0.995	0.000
Q61.4 Renal dysplasia	0.004	0.995	0.000
M45 Ankylosing spondylitis	0.005	0.995	0.000
M79.15 Myalgia (Pelvic region and thigh)	0.000	0.996	0.004
M79.1 Myalgia	0.000	0.996	0.004
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.996	0.004
N64.9 Disorder of breast, unspecified	0.004	0.996	0.000
M79.16 Myalgia (Lower leg)	0.000	0.996	0.004
N64.1 Fat necrosis of breast	0.004	0.996	0.000
M79.10 Myalgia (Multiple sites)	0.000	0.996	0.004
M95.0 Acquired deformity of nose	0.004	0.996	0.000
T42.1 Iminostilbenes	0.004	0.996	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.996	0.004
C45.9 Mesothelioma, unspecified	0.004	0.996	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.000	0.996	0.004
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.004	0.996	0.000
C45.7 Mesothelioma of other sites	0.004	0.996	0.000
T42.0 Hydantoin derivatives	0.004	0.996	0.000
N64.8 Other specified disorders of breast	0.004	0.996	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.004	0.996	0.000
I00-I02 Acute rheumatic fever	0.000	0.996	0.004
C45 Mesothelioma	0.004	0.996	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.004	0.996	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.004	0.996	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.004	0.996	0.000
I15.8 Other secondary hypertension	0.000	0.996	0.003
I15.2 Hypertension secondary to endocrine disorders	0.000	0.996	0.003
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.004	0.996	0.000
N64.3 Galactorrhoea not associated with childbirth	0.003	0.996	0.000
N64.2 Atrophy of breast	0.003	0.996	0.000
N64.0 Fissure and fistula of nipple	0.003	0.996	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.004	0.996	0.000
I15.0 Renovascular hypertension	0.000	0.996	0.003
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.003	0.996	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.003	0.996	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.003	0.996	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.003	0.996	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.003	0.996	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.003	0.996	0.000
I15.9 Seconday hypertension, unspecified	0.000	0.996	0.003
M79.11 Myalgia (Shoulder region)	0.000	0.997	0.003
C45.0 Mesothelioma of pleura	0.003	0.997	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.003	0.997	0.000
M79.17 Myalgia (Ankle and foot)	0.000	0.997	0.003
M79.14 Myalgia (Hand)	0.000	0.997	0.003
M79.13 Myalgia (Forearm)	0.000	0.997	0.003
M79.12 Myalgia (Upper arm)	0.000	0.997	0.003
S22.4 Multiple fractures of ribs	0.003	0.997	0.000
Z57.2 Occupational exposure to dust	0.003	0.997	0.000
C45.1 Mesothelioma of peritoneum	0.003	0.997	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.003	0.997	0.000
H81.3 Other peripheral vertigo	0.000	0.997	0.003
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.003	0.997	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.003	0.997	0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.003	0.997	0.000
M96.5 Postradiation scoliosis	0.003	0.997	0.000
M96.4 Postsurgical lordosis	0.003	0.997	0.000
M96.3 Postlaminectomy kyphosis	0.003	0.997	0.000
M96.2 Postradiation kyphosis	0.003	0.997	0.000
E78.5 Hyperlipidaemia, unspecified	0.000	0.997	0.003
J45.9 Asthma, unspecified	0.003	0.997	0.000
Q54.0 Hypospadias, balanic	0.003	0.997	0.000
I02 Rheumatic chorea	0.000	0.997	0.003
I01 Rheumatic fever with heart involvement	0.000	0.997	0.003
T79.4 Traumatic shock	0.003	0.997	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.997	0.003
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.003	0.997	0.000
Z92.4 Personal history of major surgery, not elsewhere classified	0.000	0.997	0.003
C45.2 Mesothelioma of pericardium	0.003	0.997	0.000
T79.9 Unspecified early complication of trauma	0.003	0.997	0.000
T79.7 Traumatic subcutaneous emphysema	0.003	0.997	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.003	0.997	0.000
T79.1 Fat embolism (traumatic)	0.003	0.997	0.000
T79.0 Air embolism (traumatic)	0.003	0.997	0.000
T79.8 Other early complications of trauma	0.003	0.997	0.000
H81 Disorders of vestibular function	0.000	0.997	0.003
M19.93 Arthrosis, unspecified (Forearm)	0.003	0.997	0.000
I00 Rheumatic fever without mention of heart involvement	0.000	0.997	0.003
T79.6 Traumatic ischaemia of muscle	0.003	0.997	0.000
S52.10 Fracture of upper end of radius (closed)	0.003	0.997	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.003	0.997	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.003	0.997	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.003	0.997	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.003	0.997	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.003	0.997	0.000
Z56.6 Other physical and mental strain related to work	0.003	0.997	0.000
H27.8 Other specified disorders of lens	0.000	0.997	0.003
E28.2 Polycystic ovarian syndrome	0.003	0.997	0.000
T91.1 Sequelae of fracture of spine	0.000	0.997	0.003
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.003	0.997	0.000
T79.5 Traumatic anuria	0.003	0.997	0.000
M95.1 Cauliflower ear	0.003	0.997	0.000
I99 Other and unspecified disorders of circulatory system	0.000	0.997	0.003
S22.41 Multiple fractures of ribs (open)	0.003	0.997	0.000
E23.2 Diabetes insipidus	0.000	0.997	0.003
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.997	0.003
N60.2 Fibroadenosis of breast	0.003	0.997	0.000
K29.8 Duodenitis	0.000	0.997	0.003
Z59 Problems related to housing and economic circumstances	0.003	0.997	0.000
Q60-Q64 Congenital malformations of the urinary system	0.003	0.997	0.000
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)	0.002	0.997	0.000
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate	0.002	0.997	0.000
I15.1 Hypertension secondary to other renal disorders	0.000	0.997	0.002
K55.2 Angiodysplasia of colon	0.003	0.997	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.002	0.997	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.997	0.002
I01.8 Other acute rheumatic heart disease	0.000	0.997	0.002
I01.2 Acute rheumatic myocarditis	0.000	0.997	0.002
I01.1 Acute rheumatic endocarditis	0.000	0.997	0.002
I01.0 Acute rheumatic pericarditis	0.000	0.997	0.002
I02.9 Rheumatic chorea without heart involvement	0.000	0.997	0.002
I02.0 Rheumatic chorea with heart involvement	0.000	0.997	0.002
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.002	0.998	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.002	0.998	0.000
M95.5 Acquired deformity of pelvis	0.002	0.998	0.000
I69.3 Sequelae of cerebral infarction	0.002	0.998	0.000
Q64 Other congenital malformations of urinary system	0.002	0.998	0.000
N75.0 Cyst of Bartholin's gland	0.000	0.998	0.002
Z59.8 Other problems relating to housing and economic circumstances	0.002	0.998	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.998	0.002
N64.4 Mastodynia	0.002	0.998	0.000
Z59.1 Inadequate housing	0.002	0.998	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.002	0.998	0.000
S02.60 Fracture of mandible (closed)	0.002	0.998	0.000
H81.4 Vertigo of central origin	0.000	0.998	0.002
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.002	0.998	0.000
S05.1 Contusion of eyeball and orbital tissues	0.000	0.998	0.002
Z57 Occupational exposure to risk-factors	0.002	0.998	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
H57.8 Other specified disorders of eye and adnexa	0.002	0.998	0.000
M95.3 Acquired deformity of neck	0.002	0.998	0.000
M99 Biomechanical lesions, not elsewhere classified	0.002	0.998	0.000
T91 Sequelae of injuries of neck and trunk	0.000	0.998	0.002
Z56 Problems related to employment and unemployment	0.002	0.998	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.000	0.998	0.002
I12 Hypertensive renal disease	0.000	0.998	0.002
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
C71.1 Frontal lobe	0.002	0.998	0.000
N76.0 Acute vaginitis	0.000	0.998	0.002
H81.8 Other disorders of vestibular function	0.000	0.998	0.002
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.002	0.998	0.000
M79.18 Myalgia (Other)	0.000	0.998	0.002
Q63 Other congenital malformations of kidney	0.002	0.998	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.002	0.998	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.998	0.002
O02.1 Missed abortion	0.002	0.998	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.000	0.998	0.002
Z59.0 Homelessness	0.002	0.998	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
M99.8 Other biomechanical lesions	0.002	0.998	0.000
T91.3 Sequelae of injury of spinal cord	0.000	0.998	0.002
Z59.7 Insufficient social insurance and welfare support	0.002	0.998	0.000
Z59.6 Low income	0.002	0.998	0.000
Z59.5 Extreme poverty	0.002	0.998	0.000
Z59.4 Lack of adequate food	0.002	0.998	0.000
Z59.3 Problems related to living in residential institution	0.002	0.998	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.002	0.998	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.002	0.998	0.000
Z61 Problems related to negative life events in childhood	0.002	0.998	0.000
H81.9 Disorder of vestibular function, unspecified	0.000	0.998	0.002
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.002	0.998	0.000
Z63.8 Other specified problems related to primary support group	0.002	0.998	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.000	0.998	0.002
T91.9 Sequelae of unspecified injury of neck and trunk	0.000	0.998	0.002
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.002	0.998	0.000
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.002	0.998	0.000
M24.01 Loose body in joint (Shoulder region)	0.002	0.998	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.002	0.998	0.000
Q64.8 Other specified congenital malformations of urinary system	0.002	0.998	0.000
Q64.6 Congenital diverticulum of bladder	0.002	0.998	0.000
Q64.5 Congenital absence of bladder and urethra	0.002	0.998	0.000
Q64.4 Malformation of urachus	0.002	0.998	0.000
Q64.2 Congenital posterior urethral valves	0.002	0.998	0.000
Q64.1 Exstrophy of urinary bladder	0.002	0.998	0.000
Q64.0 Epispadias	0.002	0.998	0.000
Z64 Problems related to certain psychosocial circumstances	0.002	0.998	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.002	0.998	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.002	0.998	0.000
H81.1 Benign paroxysmal vertigo	0.000	0.998	0.002
I49.3 Ventricular premature depolarisation	0.000	0.998	0.002
M24.4 Recurrent dislocation and subluxation of joint	0.002	0.998	0.000
M99.83 Other biomechanical lesions (Lumbar region)	0.002	0.998	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.000	0.998	0.002
H81.2 Vestibular neuronitis	0.000	0.998	0.002
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.002	0.998	0.000
M95.4 Acquired deformity of chest and rib	0.002	0.998	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.002	0.998	0.000
Z57.7 Occupational exposure to vibration	0.002	0.998	0.000
Z57.6 Occupational exposure to extreme temperature	0.002	0.998	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.002	0.998	0.000
Z57.1 Occupational exposure to radiation	0.002	0.998	0.000
Z57.0 Occupational exposure to noise	0.002	0.998	0.000
Z65 Problems related to other psychosocial circumstances	0.002	0.998	0.000
C51.9 Vulva, unspecified	0.002	0.998	0.000
M99.9 Biomechanical lesion, unspecified	0.002	0.998	0.000
M99.6 Osseous and subluxation stenosis of intervertebral foramina	0.002	0.998	0.000
M99.4 Connective tissue stenosis of neural canal	0.002	0.998	0.000
M99.3 Osseous stenosis of neural canal	0.002	0.998	0.000
M99.2 Subluxation stenosis of neural canal	0.002	0.998	0.000
M99.1 Subluxation complex (vertebral)	0.002	0.998	0.000
M99.0 Segmental and somatic dysfunction	0.002	0.998	0.000
M99.7 Connective tissue and disk stenosis of intervertebral foramina	0.002	0.998	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.000	0.998	0.002
T91.4 Sequelae of injury of intrathoracic organs	0.000	0.998	0.002
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.000	0.998	0.002
Z56.7 Other and unspecified problems related to employment	0.002	0.998	0.000
Z56.5 Uncongenial work	0.002	0.998	0.000
Z56.4 Discord with boss and workmates	0.002	0.998	0.000
Z56.2 Threat of job loss	0.002	0.998	0.000
Z56.1 Change of job	0.002	0.998	0.000
G58.8 Other specified mononeuropathies	0.002	0.998	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.002	0.998	0.000
Z57.8 Occupational exposure to other risk-factors	0.002	0.998	0.000
M95.2 Other acquired deformity of head	0.002	0.998	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.002	0.998	0.000
Z64.0 Problems related to unwanted pregnancy	0.002	0.998	0.000
B35.3 Tinea pedis	0.000	0.998	0.002
Z56.0 Unemployment, unspecified	0.002	0.998	0.000
H49.0 Third [oculomotor] nerve palsy	0.002	0.998	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.002	0.998	0.000
Q63.8 Other specified congenital malformations of kidney	0.002	0.998	0.000
Q63.3 Hyperplastic and giant kidney	0.002	0.998	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.002	0.998	0.000
Z62 Other problems related to upbringing	0.002	0.998	0.000
Z55 Problems related to education and literacy	0.002	0.998	0.000
Q63.2 Ectopic kidney	0.002	0.998	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.002	0.998	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.002	0.998	0.000
M99.89 Other biomechanical lesions (Abdomen and other)	0.002	0.998	0.000
M99.88 Other biomechanical lesions (Rib cage)	0.002	0.998	0.000
M99.87 Other biomechanical lesions (Upper extremity)	0.002	0.998	0.000
M99.86 Other biomechanical lesions (Lower extremity)	0.002	0.998	0.000
M99.85 Other biomechanical lesions (Pelvic region)	0.002	0.998	0.000
M99.84 Other biomechanical lesions (Sacral region)	0.002	0.998	0.000
M99.82 Other biomechanical lesions (Thoracic region)	0.002	0.998	0.000
M99.81 Other biomechanical lesions (Cervical region)	0.002	0.998	0.000
M99.80 Other biomechanical lesions (Head region)	0.002	0.998	0.000
M99.5 Intervertebral disk stenosis of neural canal	0.002	0.998	0.000
K61 Abscess of anal and rectal regions	0.000	0.998	0.002
Z58 Problems related to physical environment	0.002	0.998	0.000
E28.3 Primary ovarian failure	0.002	0.998	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.002	0.998	0.000
Z61.9 Negative life events in childhood, unspecified	0.002	0.998	0.000
Z61.8 Other negative life events in childhood	0.002	0.998	0.000
Z61.7 Personal frightening experience in childhood	0.002	0.998	0.000
Z61.6 Problems related to alleged physical abuse of child	0.002	0.998	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.002	0.998	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.002	0.998	0.000
Z61.2 Altered pattern of family relationships in childhood	0.002	0.998	0.000
Z61.1 Removal from home in childhood	0.002	0.998	0.000
Z61.0 Loss of love relationship in childhood	0.002	0.998	0.000
Q63.0 Accessory kidney	0.002	0.998	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.998	0.002
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.002	0.998	0.000
N90.7 Vulvar cyst	0.000	0.998	0.002
I50 Heart failure	0.000	0.998	0.002
O12.1 Gestational proteinuria	0.002	0.998	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.002	0.998	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.002	0.998	0.000
Z56.3 Stressful work schedule	0.002	0.998	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.998	0.002
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.002	0.998	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.002	0.998	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.002	0.998	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.002	0.998	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.002	0.998	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.002	0.998	0.000
I72.3 Aneurysm of iliac artery	0.000	0.998	0.002
N36.9 Urethral disorder, unspecified	0.000	0.998	0.002
Z64.4 Discord with counsellors	0.002	0.998	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.002	0.998	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.002	0.998	0.000
Z64.1 Problems related to multiparity	0.002	0.998	0.000
Q62.8 Other congenital malformations of ureter	0.001	0.998	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.001	0.998	0.000
Q62.6 Malposition of ureter	0.001	0.998	0.000
Q62.4 Agenesis of ureter	0.001	0.998	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.001	0.998	0.000
Q62.0 Congenital hydronephrosis	0.001	0.998	0.000
Z58.8 Other problems related to physical environment	0.002	0.998	0.000
E28 Ovarian dysfunction	0.002	0.998	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.998	0.002
M99.09 Segmental and somatic dysfunction (Abdomen and other)	0.001	0.998	0.000
M99.08 Segmental and somatic dysfunction (Rib cage)	0.001	0.998	0.000
M99.07 Segmental and somatic dysfunction (Upper extremity)	0.001	0.998	0.000
M99.06 Segmental and somatic dysfunction (Lower extremity)	0.001	0.998	0.000
M99.05 Segmental and somatic dysfunction (Pelvic region)	0.001	0.998	0.000
M99.04 Segmental and somatic dysfunction (Sacral region)	0.001	0.998	0.000
M99.03 Segmental and somatic dysfunction (Lumbar region)	0.001	0.998	0.000
M99.02 Segmental and somatic dysfunction (Thoracic region)	0.001	0.998	0.000
M99.01 Segmental and somatic dysfunction (Cervical region)	0.001	0.998	0.000
M99.00 Segmental and somatic dysfunction (Head region)	0.001	0.998	0.000
M99.19 Subluxation complex (vertebral) (Abdomen and other)	0.001	0.998	0.000
M99.18 Subluxation complex (vertebral) (Rib cage)	0.001	0.998	0.000
M99.17 Subluxation complex (vertebral) (Upper extremity)	0.001	0.998	0.000
M99.16 Subluxation complex (vertebral) (Lower extremity)	0.001	0.998	0.000
M99.15 Subluxation complex (vertebral) (Pelvic region)	0.001	0.998	0.000
M99.14 Subluxation complex (vertebral) (Sacral region)	0.001	0.998	0.000
M99.13 Subluxation complex (vertebral) (Lumbar region)	0.001	0.998	0.000
M99.12 Subluxation complex (vertebral) (Thoracic region)	0.001	0.998	0.000
M99.11 Subluxation complex (vertebral) (Cervical region)	0.001	0.998	0.000
M99.10 Subluxation complex (vertebral) (Head region)	0.001	0.998	0.000
M99.29 Subluxation stenosis of neural canal-Abdomen/other	0.001	0.998	0.000
M99.28 Subluxation stenosis of neural canal-Rib cage	0.001	0.998	0.000
M99.27 Subluxation stenosis of neural canal-Upper extremity	0.001	0.998	0.000
M99.26 Subluxation stenosis of neural canal-Lower extremity	0.001	0.998	0.000
M99.25 Subluxation stenosis of neural canal (Pelvic region)	0.001	0.998	0.000
M99.24 Subluxation stenosis of neural canal (Sacral region)	0.001	0.998	0.000
M99.23 Subluxation stenosis of neural canal (Lumbar region)	0.001	0.998	0.000
M99.22 Subluxation stenosis of neural canal (Thoracic region)	0.001	0.998	0.000
M99.21 Subluxation stenosis of neural canal (Cervical region)	0.001	0.998	0.000
M99.20 Subluxation stenosis of neural canal (Head region)	0.001	0.998	0.000
M99.39 Osseous stenosis of neural canal-Abdomen/other	0.001	0.998	0.000
M99.38 Osseous stenosis of neural canal-Rib cage	0.001	0.998	0.000
M99.37 Osseous stenosis of neural canal-Upper extremity	0.001	0.998	0.000
M99.36 Osseous stenosis of neural canal-Lower extremity	0.001	0.998	0.000
M99.35 Osseous stenosis of neural canal (Pelvic region)	0.001	0.998	0.000
M99.34 Osseous stenosis of neural canal (Sacral region)	0.001	0.998	0.000
M99.33 Osseous stenosis of neural canal (Lumbar region)	0.001	0.998	0.000
M99.32 Osseous stenosis of neural canal (Thoracic region)	0.001	0.998	0.000
M99.31 Osseous stenosis of neural canal (Cervical region)	0.001	0.998	0.000
M99.30 Osseous stenosis of neural canal (Head region)	0.001	0.998	0.000
M99.49 Connective tissue stenosis of neural canal-Abdomen/other	0.001	0.998	0.000
M99.48 Connective tissue stenosis of neural canal-Rib cage	0.001	0.998	0.000
M99.47 Connective tissue stenosis of neural canal-Upper extremity	0.001	0.998	0.000
M99.46 Connective tissue stenosis of neural canal-Lower extremity	0.001	0.998	0.000
M99.45 Connective tissue stenosis of neural canal (Pelvic region)	0.001	0.998	0.000
M99.44 Connective tissue stenosis of neural canal (Sacral region)	0.001	0.998	0.000
M99.43 Connective tissue stenosis of neural canal (Lumbar region)	0.001	0.998	0.000
M99.42 Connective tissue stenosis of neural canal (Thoracic region)	0.001	0.998	0.000
M99.41 Connective tissue stenosis of neural canal (Cervical region)	0.001	0.998	0.000
M99.40 Connective tissue stenosis of neural canal (Head region)	0.001	0.998	0.000
M99.69 Osseous and subluxation stenosis of intervertebral foramina	0.001	0.998	0.000
M99.68 Osseous and subluxation stenosis of intervertebral foramina	0.001	0.998	0.000
M99.67 Osseous and subluxation stenosis of intervertebral foramina	0.001	0.998	0.000
M99.66 Osseous and subluxation stenosis of intervertebral foramina	0.001	0.998	0.000
M99.65 Osseous and subluxation stenosis of intervertebral foramina (Pelvic region)	0.001	0.998	0.000
M99.64 Osseous and subluxation stenosis of intervertebral foramina (Sacral region)	0.001	0.998	0.000
M99.63 Osseous and subluxation stenosis of intervertebral foramina (Lumbar region)	0.001	0.998	0.000
M99.62 Osseous and subluxation stenosis of intervertebral foramina (Thoracic region)	0.001	0.998	0.000
M99.61 Osseous and subluxation stenosis of intervertebral foramina (Cervical region)	0.001	0.998	0.000
M99.60 Osseous and subluxation stenosis of intervertebral foramina (Head region)	0.001	0.998	0.000
M99.99 Biomechanical lesion, unspecified (Abdomen and other)	0.001	0.998	0.000
M99.98 Biomechanical lesion, unspecified (Rib cage)	0.001	0.998	0.000
M99.97 Biomechanical lesion, unspecified (Upper extremity)	0.001	0.998	0.000
M99.96 Biomechanical lesion, unspecified (Lower extremity)	0.001	0.998	0.000
M99.95 Biomechanical lesion, unspecified (Pelvic region)	0.001	0.998	0.000
M99.94 Biomechanical lesion, unspecified (Sacral region)	0.001	0.998	0.000
M99.93 Biomechanical lesion, unspecified (Lumbar region)	0.001	0.998	0.000
M99.92 Biomechanical lesion, unspecified (Thoracic region)	0.001	0.998	0.000
M99.91 Biomechanical lesion, unspecified (Cervical region)	0.001	0.998	0.000
M99.90 Biomechanical lesion, unspecified (Head region)	0.001	0.998	0.000
Z65.8 Other specified problems related to psychosocial circumstances	0.001	0.998	0.000
Z65.5 Exposure to disaster, war and other hostilities	0.001	0.998	0.000
Z65.4 Victim of crime and terrorism	0.001	0.998	0.000
Z65.3 Problems related to other legal circumstances	0.001	0.998	0.000
Z65.2 Problems related to release from prison	0.001	0.998	0.000
Z65.1 Imprisonment and other incarceration	0.001	0.998	0.000
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.001	0.998	0.000
M76.66 Achilles tendinitis (Lower leg)	0.000	0.998	0.002
M99.79 Connective tis and disc stenosis of intervertebral foramina	0.001	0.998	0.000
M99.78 Connective tis and disc stenosis of intervertebral foramina	0.001	0.998	0.000
M99.77 Connective tis and disc stenosis of intervertebral foramina	0.001	0.998	0.000
M99.76 Connective tis and disc stenosis of intervertebral foramina	0.001	0.998	0.000
M99.75 Connective tissue and disc stenosis of intervertebral foramina (Pelvic region)	0.001	0.998	0.000
M99.74 Connective tissue and disc stenosis of intervertebral foramina (Sacral region)	0.001	0.998	0.000
M99.72 Connective tissue and disc stenosis of intervertebral foramina (Thoracic region)	0.001	0.998	0.000
M99.71 Connective tissue and disc stenosis of intervertebral foramina (Cervical region)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations