TreeWAS – Variant ID: rs12190789

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	1.000	0.000	0.000
E83 Disorders of mineral metabolism	0.180	0.820	0.000
N81.4 Uterovaginal prolapse, unspecified	0.159	0.841	0.000
E83.3 Disorders of phosphorus metabolism	0.157	0.843	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.129	0.870	0.000
E83.8 Other disorders of mineral metabolism	0.129	0.870	0.000
E83.2 Disorders of zinc metabolism	0.129	0.870	0.000
E83.0 Disorders of copper metabolism	0.129	0.870	0.000
E83.4 Disorders of magnesium metabolism	0.072	0.928	0.000
R03.1 Nonspecific low blood-pressure reading	0.048	0.952	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.975	0.025
T50.9 Other and unspecified drugs, medicaments and biological substances	0.019	0.981	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.000	0.985	0.015
H04 Disorders of lachrymal system	0.000	0.987	0.013
R03 Abnormal blood-pressure reading, without diagnosis	0.013	0.987	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.012	0.988	0.000
H04.1 Other disorders of lachrymal gland	0.000	0.989	0.011
H04.8 Other disorders of lachrymal system	0.000	0.989	0.011
H04.4 Chronic inflammation of lachrymal passages	0.000	0.989	0.011
J03.9 Acute tonsillitis, unspecified	0.000	0.989	0.011
H04.3 Acute and unspecified inflammation of lachrymal passages	0.000	0.989	0.011
E83.5 Disorders of calcium metabolism	0.010	0.989	0.001
E03 Other hypothyroidism	0.000	0.989	0.010
T50.6 Antidotes and chelating agents, not elsewhere classified	0.010	0.990	0.000
T50.8 Diagnostic agents	0.010	0.990	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.010	0.990	0.000
H04.2 Epiphora	0.000	0.990	0.010
H04.6 Other changes in lachrymal passages	0.000	0.990	0.010
H04.0 Dacryoadenitis	0.000	0.990	0.010
H04.9 Disorder of lachrymal system, unspecified	0.000	0.990	0.009
T50.7 Analeptics and opioid receptor antagonists	0.009	0.991	0.000
T50.5 Appetite depressants	0.009	0.991	0.000
T50.4 Drugs affecting uric acid metabolism	0.009	0.991	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.009	0.991	0.000
T50.1 Loop [high-ceiling] diuretics	0.009	0.991	0.000
T50.0 Mineralocorticoids and their antagonists	0.009	0.991	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.009	0.991	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.009	0.991	0.000
E03.8 Other specified hypothyroidism	0.000	0.992	0.008
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.008	0.992	0.000
E03.5 Myxoedema coma	0.000	0.992	0.008
E03.4 Atrophy of thyroid (acquired)	0.000	0.992	0.008
E03.3 Postinfectious hypothyroidism	0.000	0.992	0.008
E03.1 Congenital hypothyroidism without goitre	0.000	0.992	0.008
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.992	0.008
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.007	0.993	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.007	0.993	0.000
Z60.2 Living alone	0.000	0.993	0.007
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.994	0.006
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.006	0.994	0.000
J03 Acute tonsillitis	0.000	0.994	0.006
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.006	0.994	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.006	0.994	0.000
C15.5 Lower third of oesophagus	0.006	0.994	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.006	0.994	0.000
R30.0 Dysuria	0.006	0.994	0.000
Z43.3 Attention to colostomy	0.000	0.995	0.005
T84.0 Mechanical complication of internal joint prosthesis	0.005	0.995	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.005	0.995	0.000
G47.3 Sleep apnoea	0.000	0.995	0.005
G57.8 Other mononeuropathies of lower limb	0.005	0.995	0.000
J03.8 Acute tonsillitis due to other specified organisms	0.000	0.995	0.004
J03.0 Streptococcal tonsillitis	0.000	0.995	0.004
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.005	0.995	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.004	0.996	0.000
R16.1 Splenomegaly, not elsewhere classified	0.000	0.996	0.004
G57.6 Lesion of plantar nerve	0.004	0.996	0.000
G57 Mononeuropathies of lower limb	0.004	0.996	0.000
G57.3 Lesion of lateral popliteal nerve	0.004	0.996	0.000
Z60 Problems related to social environment	0.000	0.996	0.004
D45 Polycythaemia vera	0.004	0.996	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.004	0.996	0.000
Y83.1 Surgical operation with implant of artificial internal device	0.004	0.996	0.000
J39.2 Other diseases of pharynx	0.000	0.996	0.004
C25.9 Pancreas, unspecified	0.003	0.997	0.000
G57.9 Mononeuropathy of lower limb, unspecified	0.003	0.997	0.000
F20.9 Schizophrenia, unspecified	0.000	0.997	0.003
J32.9 Chronic sinusitis, unspecified	0.000	0.997	0.003
G57.4 Lesion of medial popliteal nerve	0.003	0.997	0.000
G57.2 Lesion of femoral nerve	0.003	0.997	0.000
G57.0 Lesion of sciatic nerve	0.003	0.997	0.000
G57.1 Meralgia paraesthetica	0.003	0.997	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.997	0.003
Z60.9 Problem related to social environment, unspecified	0.000	0.997	0.003
Z60.8 Other problems related to social environment	0.000	0.997	0.003
Z60.5 Target of perceived adverse discrimination and persecution	0.000	0.997	0.003
Z60.4 Social exclusion and rejection	0.000	0.997	0.003
Z60.3 Acculturation difficulty	0.000	0.997	0.003
Z60.1 Atypical parenting situation	0.000	0.997	0.003
Z60.0 Problems of adjustment to life-cycle transitions	0.000	0.997	0.003
G57.5 Tarsal tunnel syndrome	0.003	0.997	0.000
C25 Malignant neoplasm of pancreas	0.003	0.997	0.000
C15 Malignant neoplasm of oesophagus	0.003	0.997	0.000
C15.3 Upper third of oesophagus	0.003	0.997	0.000
C25.4 Endocrine pancreas	0.003	0.997	0.000
M21.3 Wrist or foot drop (acquired)	0.003	0.997	0.000
C25.0 Head of pancreas	0.003	0.997	0.000
Z45.8 Adjustment and management of other implanted devices	0.000	0.997	0.003
C25.1 Body of pancreas	0.003	0.997	0.000
F20 Schizophrenia	0.000	0.997	0.003
F29 Unspecified nonorganic psychosis	0.000	0.997	0.003
E89.2 Postprocedural hypoparathyroidism	0.000	0.997	0.003
C15.1 Thoracic part of oesophagus	0.003	0.997	0.000
C25.3 Pancreatic duct	0.003	0.997	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
C77.1 Intrathoracic lymph nodes	0.003	0.997	0.000
F22.0 Delusional disorder	0.000	0.997	0.003
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.997	0.002
N81 Female genital prolapse	0.003	0.997	0.000
C15.4 Middle third of oesophagus	0.002	0.997	0.000
F22 Persistent delusional disorders	0.000	0.998	0.002
C15.8 Overlapping lesion of oesophagus	0.002	0.998	0.000
C15.2 Abdominal part of oesophagus	0.002	0.998	0.000
C15.0 Cervical part of oesophagus	0.002	0.998	0.000
C25.8 Overlapping lesion of pancreas	0.002	0.998	0.000
C25.7 Other parts of pancreas	0.002	0.998	0.000
J35.1 Hypertrophy of tonsils	0.000	0.998	0.002
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.998	0.002
N81.5 Vaginal enterocele	0.002	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
F20.0 Paranoid schizophrenia	0.000	0.998	0.002
Z43.1 Attention to gastrostomy	0.000	0.998	0.002
M21.39 Wrist or foot drop (acquired)-Site unspec	0.002	0.998	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.002	0.998	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.002	0.998	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.002	0.998	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.002	0.998	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.002	0.998	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.002	0.998	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.002	0.998	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.002	0.998	0.000
D41.4 Bladder	0.002	0.998	0.000
C25.2 Tail of pancreas	0.002	0.998	0.000
F20.8 Other schizophrenia	0.000	0.998	0.002
F20.6 Simple schizophrenia	0.000	0.998	0.002
F20.4 Postschizophrenic depression	0.000	0.998	0.002
F20.3 Undifferentiated schizophrenia	0.000	0.998	0.002
F20.2 Catatonic schizophrenia	0.000	0.998	0.002
F20.1 Hebephrenic schizophrenia	0.000	0.998	0.002
J00-J06 Acute upper respiratory infections	0.000	0.998	0.002
L71.9 Rosacea, unspecified	0.002	0.998	0.000
N81.0 Female urethrocele	0.002	0.998	0.000
Z43 Attention to artificial openings	0.000	0.998	0.002
E66.8 Other obesity	0.000	0.998	0.002
Z43.8 Attention to other artificial openings	0.000	0.998	0.002
C16.9 Stomach, unspecified	0.002	0.998	0.000
C16.5 Lesser curvature of stomach, unspecified	0.002	0.998	0.000
E89.3 Postprocedural hypopituitarism	0.000	0.998	0.002
S81.0 Open wound of knee	0.002	0.998	0.000
S81.9 Open wound of lower leg, part unspecified	0.002	0.998	0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.000	0.998	0.002
E06.3 Autoimmune thyroiditis	0.000	0.998	0.002
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.998	0.002
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.998	0.002
E89.5 Postprocedural testicular hypofunction	0.000	0.998	0.002
E89.4 Postprocedural ovarian failure	0.000	0.998	0.002
E89.1 Postprocedural hypoinsulinaemia	0.000	0.998	0.002
J00 Acute nasopharyngitis [common cold]	0.000	0.998	0.002
F20.5 Residual schizophrenia	0.000	0.998	0.002
M21.0 Valgus deformity, not elsewhere classified	0.002	0.998	0.000
J39 Other diseases of upper respiratory tract	0.000	0.998	0.002
F22.9 Persistent delusional disorder, unspecified	0.000	0.998	0.002
F22.8 Other persistent delusional disorders	0.000	0.998	0.002
F25 Schizoaffective disorders	0.000	0.998	0.002
E00-E07 Disorders of thyroid gland	0.000	0.998	0.002
F28 Other nonorganic psychotic disorders	0.000	0.998	0.002
F24 Induced delusional disorder	0.000	0.998	0.002
F21 Schizotypal disorder	0.000	0.998	0.002
J05.1 Acute epiglottitis	0.000	0.998	0.002
J04 Acute laryngitis and tracheitis	0.000	0.998	0.002
D18.0 Haemangioma, any site	0.000	0.998	0.002
J39.8 Other specified diseases of upper respiratory tract	0.000	0.998	0.002
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.998	0.002
N64.5 Other signs and symptoms in breast	0.000	0.998	0.002
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
Z56.0 Unemployment, unspecified	0.000	0.998	0.002
Z56 Problems related to employment and unemployment	0.000	0.998	0.002
M79.0 Rheumatism, unspecified	0.002	0.998	0.000
Q82.8 Other specified congenital malformations of skin	0.002	0.998	0.000
E06 Thyroiditis	0.000	0.998	0.002
Z43.9 Attention to unspecified artificial opening	0.000	0.998	0.002
Z43.7 Attention to artificial vagina	0.000	0.998	0.002
Z43.0 Attention to tracheostomy	0.000	0.998	0.002
Z56.6 Other physical and mental strain related to work	0.000	0.998	0.002
N64.9 Disorder of breast, unspecified	0.000	0.998	0.002
Q82.5 Congenital nonneoplastic naevus	0.002	0.998	0.000
Z43.6 Attention to other artificial openings of urinary tract	0.000	0.998	0.002
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.998	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
S81 Open wound of lower leg	0.002	0.998	0.000
F25.1 Schizoaffective disorder, depressive type	0.000	0.998	0.002
C16 Malignant neoplasm of stomach	0.002	0.998	0.000
Z56.3 Stressful work schedule	0.000	0.998	0.002
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.002	0.998	0.000
F23 Acute and transient psychotic disorders	0.000	0.998	0.002
I72.3 Aneurysm of iliac artery	0.000	0.998	0.002
D38.1 Trachea, bronchus and lung	0.002	0.998	0.000
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
K51.3 Ulcerative (chronic) rectosigmoiditis	0.002	0.998	0.000
E23.0 Hypopituitarism	0.000	0.998	0.002
G47.8 Other sleep disorders	0.000	0.998	0.002
I46.0 Cardiac arrest with successful resuscitation	0.002	0.998	0.000
J05.0 Acute obstructive laryngitis [croup]	0.000	0.998	0.002
J39.0 Retropharyngeal and parapharyngeal abscess	0.000	0.998	0.002
K51.2 Ulcerative (chronic) proctitis	0.002	0.998	0.000
N81.3 Complete uterovaginal prolapse	0.002	0.998	0.000
J01 Acute sinusitis	0.000	0.998	0.002
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.002	0.998	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.002	0.998	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.002	0.998	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.000	0.998	0.002
J39.1 Other abscess of pharynx	0.000	0.998	0.002
Z43.4 Attention to other artificial openings of digestive tract	0.000	0.998	0.002
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.002	0.998	0.000
G47 Sleep disorders	0.000	0.998	0.002
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
D40.7 Other male genital organs	0.002	0.998	0.000
F25.8 Other schizoaffective disorders	0.000	0.998	0.002
F25.2 Schizoaffective disorder, mixed type	0.000	0.998	0.002
F25.0 Schizoaffective disorder, manic type	0.000	0.998	0.002
J04.0 Acute laryngitis	0.000	0.998	0.002
Q82 Other congenital malformations of skin	0.002	0.998	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.002	0.998	0.000
C16.3 Pyloric antrum	0.002	0.998	0.000
J04.1 Acute tracheitis	0.000	0.998	0.002
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.998	0.002
E00 Congenital iodine-deficiency syndrome	0.000	0.998	0.002
C18.2 Ascending colon	0.000	0.998	0.002
D37-D48 Neoplasms of uncertain or unknown behaviour	0.002	0.998	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.002	0.998	0.000
M79.08 Rheumatism, unspecified (Other)	0.002	0.998	0.000
M79.01 Rheumatism, unspecified (Shoulder region)	0.002	0.998	0.000
J01.9 Acute sinusitis, unspecified	0.000	0.998	0.002
J04.2 Acute laryngotracheitis	0.000	0.998	0.002
Z56.7 Other and unspecified problems related to employment	0.000	0.998	0.002
Z56.5 Uncongenial work	0.000	0.998	0.002
Z56.4 Discord with boss and workmates	0.000	0.998	0.002
Z56.2 Threat of job loss	0.000	0.998	0.002
Z56.1 Change of job	0.000	0.998	0.002
M79.07 Rheumatism, unspecified (Ankle and foot)	0.002	0.998	0.000
M79.06 Rheumatism, unspecified (Lower leg)	0.002	0.998	0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M79.04 Rheumatism, unspecified (Hand)	0.002	0.998	0.000
M79.03 Rheumatism, unspecified (Forearm)	0.002	0.998	0.000
M79.02 Rheumatism, unspecified (Upper arm)	0.002	0.998	0.000
Q83.1 Accessory breast	0.002	0.998	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.000	0.998	0.002
S81.7 Multiple open wounds of lower leg	0.002	0.998	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.998	0.002
E06.4 Drug-induced thyroiditis	0.000	0.998	0.001
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.998	0.001
E06.1 Subacute thyroiditis	0.000	0.998	0.001
E06.0 Acute thyroiditis	0.000	0.998	0.001
M87.9 Osteonecrosis, unspecified	0.002	0.998	0.000
D48.0 Bone and articular cartilage	0.002	0.998	0.000
E84.9 Cystic fibrosis, unspecified	0.002	0.998	0.000
G82.5 Tetraplegia, unspecified	0.002	0.998	0.000
J39.9 Disease of upper respiratory tract, unspecified	0.000	0.998	0.001
M21.4 Flat foot [pes planus] (acquired)	0.002	0.998	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.001	0.998	0.000
E66 Obesity	0.000	0.998	0.002
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.998	0.002
C16.6 Greater curvature of stomach, unspecified	0.002	0.998	0.000
C45.9 Mesothelioma, unspecified	0.002	0.998	0.000
E06.9 Thyroiditis, unspecified	0.000	0.998	0.001
E66.9 Obesity, unspecified	0.000	0.998	0.002
F25.9 Schizoaffective disorder, unspecified	0.000	0.998	0.001
N81.9 Female genital prolapse, unspecified	0.002	0.998	0.000
C16.8 Overlapping lesion of stomach	0.001	0.998	0.000
C16.4 Pylorus	0.001	0.998	0.000
C16.1 Fundus of stomach	0.001	0.998	0.000
C45.7 Mesothelioma of other sites	0.002	0.998	0.000
I72.0 Aneurysm of carotid artery	0.000	0.998	0.002
K86.8 Other specified diseases of pancreas	0.002	0.998	0.000
R73.9 Hyperglycaemia, unspecified	0.000	0.998	0.002
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.002	0.998	0.000
Z43.5 Attention to cyctostomy	0.000	0.998	0.001
M21 Other acquired deformities of limbs	0.002	0.998	0.000
C16.0 Cardia	0.002	0.998	0.000
D41.9 Urinary organ, unspecified	0.001	0.998	0.000
D41.7 Other urinary organs	0.001	0.998	0.000
D41.3 Urethra	0.001	0.998	0.000
D41.1 Renal pelvis	0.001	0.998	0.000
F23.8 Other acute and transient psychotic disorders	0.000	0.998	0.001
F23.3 Other acute predominantly delusional psychotic disorders	0.000	0.998	0.001
F23.2 Acute schizophrenia-like psychotic disorder	0.000	0.998	0.001
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.000	0.998	0.001
S81.8 Open wound of other parts of lower leg	0.002	0.998	0.000
D46 Myelodysplastic syndromes	0.002	0.998	0.000
G03.9 Meningitis, unspecified	0.002	0.998	0.000
D44.3 Pituitary gland	0.001	0.998	0.000
G47.4 Narcolepsy and cataplexy	0.000	0.998	0.001
S51.9 Open wound of forearm, part unspecified	0.002	0.998	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.000	0.998	0.002
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.001	0.998	0.000
D38.0 Larynx	0.001	0.998	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.002	0.998	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.000	0.998	0.001
G12.2 Motor neuron disease	0.000	0.998	0.002
J01.4 Acute pansinusitis	0.000	0.998	0.001
J01.3 Acute sphenoidal sinusitis	0.000	0.998	0.001
J01.2 Acute ethmoidal sinusitis	0.000	0.998	0.001
J01.1 Acute frontal sinusitis	0.000	0.998	0.001
M21.8 Other specified acquired deformities of limbs	0.001	0.998	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.001
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.001	0.998	0.000
E07 Other disorders of thyroid	0.000	0.998	0.002
C16.2 Body of stomach	0.001	0.998	0.000
D38.6 Respiratory organ, unspecified	0.001	0.998	0.000
D38.5 Other respiratory organs	0.001	0.998	0.000
D38.4 Thymus	0.001	0.998	0.000
D38.3 Mediastinum	0.001	0.998	0.000
D38.2 Pleura	0.001	0.998	0.000
D40.1 Testis	0.001	0.998	0.000
G47.2 Disorders of the sleep-wake schedule	0.000	0.998	0.001
K86.1 Other chronic pancreatitis	0.002	0.998	0.000
N85.8 Other specified noninflammatory disorders of uterus	0.002	0.998	0.000
Q82.9 Congenital malformation of skin, unspecified	0.001	0.998	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.001	0.998	0.000
Q82.3 Incontinentia pigmenti	0.001	0.998	0.000
Q82.2 Mastocytosis	0.001	0.998	0.000
Q82.1 Xeroderma pigmentosum	0.001	0.998	0.000
Q82.0 Hereditary lymphoedema	0.001	0.998	0.000
E84 Cystic fibrosis	0.001	0.998	0.000
D41.2 Ureter	0.001	0.998	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.998	0.001
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.998	0.001
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.998	0.001
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.998	0.001
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.998	0.001
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.998	0.001
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.998	0.001
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.998	0.001
I72.4 Aneurysm of artery of lower extremity	0.000	0.998	0.002
C73 Malignant neoplasm of thyroid gland	0.000	0.998	0.002
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.001	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.001	0.998	0.000
Z30.1 Insertion of (intra-uterine) contraceptive device	0.000	0.998	0.002
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.001	0.998	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
O36.9 Maternal care for foetal problem, unspecified	0.000	0.998	0.001
C45 Mesothelioma	0.001	0.998	0.000
N64 Other disorders of breast	0.000	0.998	0.001
R30 Pain associated with micturition	0.001	0.998	0.000
Z63.4 Disappearance and death of family member	0.000	0.999	0.001
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.001	0.999	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.001	0.999	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.001	0.999	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.001	0.999	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.001	0.999	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.001	0.999	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.001	0.999	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.001	0.999	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.001	0.999	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.001	0.999	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.001	0.999	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.001	0.999	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.001	0.999	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.001	0.999	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.001	0.999	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.001	0.999	0.000
D40.9 Male genital organ, unspecified	0.001	0.999	0.000
E66.1 Drug-induced obesity	0.000	0.999	0.001
E66.0 Obesity due to excess calories	0.000	0.999	0.001
E70-E90 Metabolic disorders	0.001	0.999	0.000
D46.7 Other myelodysplastic syndromes	0.001	0.999	0.000
E06.5 Other chronic thyroiditis	0.000	0.999	0.001
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.000	0.999	0.001
G47.1 Disorders of excessive somnolence [hypersomnias]	0.000	0.999	0.001
J01.8 Other acute sinusitis	0.000	0.999	0.001
L71.1 Rhinophyma	0.001	0.999	0.000
M21.9 Acquired deformity of limb, unspecified	0.001	0.999	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.001	0.999	0.000
N64.8 Other specified disorders of breast	0.000	0.999	0.001
Y41.1 Antimycobacterial drugs	0.001	0.999	0.000
Y60.0 During surgical operation	0.000	0.999	0.001
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.001	0.999	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.001	0.999	0.000
D46.4 Refractory anaemia, unspecified	0.001	0.999	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.001	0.999	0.000
D46.1 Refractory anaemia with sideroblasts	0.001	0.999	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.001	0.999	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.001	0.999	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.001	0.999	0.000
D73.0 Hyposplenism	0.000	0.999	0.001
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.001	0.999	0.000
C45.0 Mesothelioma of pleura	0.001	0.999	0.000
D44.9 Endocrine gland, unspecified	0.001	0.999	0.000
D44.7 Aortic body and other paraganglia	0.001	0.999	0.000
D44.6 Carotid body	0.001	0.999	0.000
D44.5 Pineal gland	0.001	0.999	0.000
D44.4 Craniopharyngeal duct	0.001	0.999	0.000
D44.2 Parathyroid gland	0.001	0.999	0.000
J32.8 Other chronic sinusitis	0.000	0.999	0.001
Z63.5 Disruption of family by separation and divorce	0.000	0.999	0.001
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.001	0.999	0.000
E74 Other disorders of carbohydrate metabolism	0.001	0.999	0.000
Q83 Congenital malformations of breast	0.001	0.999	0.000
Z65 Problems related to other psychosocial circumstances	0.000	0.999	0.001
Z62 Other problems related to upbringing	0.000	0.999	0.001
Z55 Problems related to education and literacy	0.000	0.999	0.001
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.001	0.999	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.001	0.999	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.001	0.999	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.001	0.999	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.001	0.999	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.001	0.999	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.001	0.999	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.001	0.999	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.001	0.999	0.000
M43.06 Spondylolysis (Lumbar region)	0.001	0.999	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.001	0.999	0.000
D44.0 Thyroid gland	0.001	0.999	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.999	0.001
E07.8 Other specified disorders of thyroid	0.000	0.999	0.001
E07.1 Dyshormogenetic goitre	0.000	0.999	0.001
E07.0 Hypersecretion of calcitonin	0.000	0.999	0.001
E84.8 Cystic fibrosis with other manifestations	0.001	0.999	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.001	0.999	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.001	0.999	0.000
M21.7 Unequal limb length (acquired)	0.001	0.999	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.001	0.999	0.000
Z63 Other problems related to primary support group, including family circumstances	0.000	0.999	0.001
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.001	0.999	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.999	0.001
C78.2 Secondary malignant neoplasm of pleura	0.001	0.999	0.000
D42.9 Meninges, unspecified	0.001	0.999	0.000
D42.1 Spinal meninges	0.001	0.999	0.000
D42.0 Cerebral meninges	0.001	0.999	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.001	0.999	0.000
J01.0 Acute maxillary sinusitis	0.000	0.999	0.001
K65.8 Other peritonitis	0.001	0.999	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.001	0.999	0.000
O87.2 Haemorrhoids in the puerperium	0.001	0.999	0.000
J02 Acute pharyngitis	0.000	0.999	0.001
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.000	0.999	0.001
L50.9 Urticaria, unspecified	0.001	0.999	0.000
Z58 Problems related to physical environment	0.000	0.999	0.001
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
C45.2 Mesothelioma of pericardium	0.001	0.999	0.000
C45.1 Mesothelioma of peritoneum	0.001	0.999	0.000
D22.5 Melanocytic naevi of trunk	0.000	0.999	0.001
D44.8 Pluriglandular involvement	0.001	0.999	0.000
G82.2 Paraplegia, unspecified	0.001	0.999	0.000
G82.1 Spastic paraplegia	0.001	0.999	0.000
N64.3 Galactorrhoea not associated with childbirth	0.000	0.999	0.001
N64.2 Atrophy of breast	0.000	0.999	0.001
N64.0 Fissure and fistula of nipple	0.000	0.999	0.001
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.001	0.999	0.000
I72 Other aneurysm	0.000	0.999	0.001
L71 Rosacea	0.001	0.999	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.001	0.999	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.999	0.001
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.999	0.001
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.001	0.999	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
E79 Disorders of purine and pyrimidine metabolism	0.001	0.999	0.000
E77 Disorders of glycoprotein metabolism	0.001	0.999	0.000
E76 Disorders of glycosaminoglycan metabolism	0.001	0.999	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.001	0.999	0.000
E72 Other disorders of amino-acid metabolism	0.001	0.999	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.001	0.999	0.000
E70 Disorders of aromatic amino-acid metabolism	0.001	0.999	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.001	0.999	0.000
J35 Chronic diseases of tonsils and adenoids	0.000	0.999	0.001
Z61 Problems related to negative life events in childhood	0.000	0.999	0.001
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.001	0.999	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.001	0.999	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.001	0.999	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.001	0.999	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.001	0.999	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.001	0.999	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.001	0.999	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.001	0.999	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.001	0.999	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.001	0.999	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.001	0.999	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.001	0.999	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.001	0.999	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.001	0.999	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.001	0.999	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.001	0.999	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.001	0.999	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations