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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12191877
log Bayes Factor = 137.074
Chromosome 6   position 31,252,925  (GRCh37) Explore rs12191877 on Ensembl!
Variant rs12191877 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
L40.0 Psoriasis vulgaris
1.000 0.000 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
M07.3 Other psoriatic arthropathies
0.999 0.001 0.000
E10.9 Without complications
0.000 0.001 0.999
M07.30 Other psoriatic arthropathies (Multiple sites)
0.993 0.007 0.000
E10-E14 Diabetes mellitus
0.000 0.008 0.992
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.008 0.992
E05.9 Thyrotoxicosis, unspecified
0.000 0.010 0.990
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.025 0.975
E07 Other disorders of thyroid
0.000 0.060 0.940
E10.3 With ophthalmic complications
0.000 0.066 0.934
E10.4 With neurological complications
0.000 0.090 0.910
E07.9 Disorder of thyroid, unspecified
0.000 0.106 0.894
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.107 0.893
E10.1 With ketoacidosis
0.000 0.107 0.893
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.876 0.124 0.000
L40.8 Other psoriasis
0.874 0.126 0.000
L40.1 Generalised pustular psoriasis
0.873 0.127 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.846 0.154 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.837 0.162 0.000
E10.2 With renal complications
0.000 0.168 0.832
E16 Other disorders of pancreatic internal secretion
0.000 0.178 0.822
L40.4 Guttate psoriasis
0.821 0.179 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.807 0.193 0.000
E10.5 With peripheral circulatory complications
0.000 0.209 0.791
E20-E35 Disorders of other endocrine glands
0.000 0.210 0.790
E16.2 Hypoglycaemia, unspecified
0.000 0.217 0.783
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.271 0.729
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.284 0.716
E10.6 With other specified complications
0.000 0.284 0.716
E10.0 With coma
0.000 0.284 0.716
E05.8 Other thyrotoxicosis
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
M07.38 Other psoriatic arthropathies (Other)
0.716 0.284 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.716 0.284 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.716 0.284 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.716 0.284 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.289 0.711
E10.8 With unspecified complications
0.000 0.291 0.709
E07.8 Other specified disorders of thyroid
0.000 0.305 0.695
E28 Ovarian dysfunction
0.000 0.319 0.681
E40-E46 Malnutrition
0.000 0.321 0.679
E07.1 Dyshormogenetic goitre
0.000 0.326 0.674
E07.0 Hypersecretion of calcitonin
0.000 0.326 0.674
E27 Other disorders of adrenal gland
0.000 0.337 0.663
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.338 0.662
E06 Thyroiditis
0.000 0.341 0.659
E29 Testicular dysfunction
0.000 0.341 0.659
E15 Nondiabetic hypoglycaemic coma
0.000 0.360 0.640
E04 Other non-toxic goitre
0.000 0.361 0.639
E14 Unspecified diabetes mellitus
0.000 0.365 0.635
E27.1 Primary adrenocortical insufficiency
0.000 0.367 0.633
E20 Hypoparathyroidism
0.000 0.382 0.618
E13 Other specified diabetes mellitus
0.000 0.384 0.615
E34 Other endocrine disorders
0.000 0.388 0.612
E26 Hyperaldosteronism
0.000 0.400 0.600
E28.2 Polycystic ovarian syndrome
0.000 0.405 0.595
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.410 0.590
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.410 0.590
E16.4 Abnormal secretion of gastrin
0.000 0.410 0.590
E16.3 Increased secretion of glucagon
0.000 0.410 0.590
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.410 0.590
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.433 0.567
E32 Diseases of thymus
0.000 0.433 0.567
E31 Polyglandular dysfunction
0.000 0.433 0.567
E30 Disorders of puberty, not elsewhere classified
0.000 0.433 0.567
E29.1 Testicular hypofunction
0.000 0.436 0.564
E04.9 Non-toxic goitre, unspecified
0.000 0.441 0.559
E16.1 Other hypoglycaemia
0.000 0.475 0.525
E22 Hyperfunction of pituitary gland
0.000 0.476 0.523
E14.3 With ophthalmic complications
0.000 0.478 0.522
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.490 0.510
E12.8 With unspecified complications
0.000 0.490 0.510
E12.7 With multiple complications
0.000 0.490 0.510
E12.6 With other specified complications
0.000 0.490 0.510
E12.5 With peripheral circulatory complications
0.000 0.490 0.510
E12.4 With neurological complications
0.000 0.490 0.510
E12.3 With ophthalmic complications
0.000 0.490 0.510
E12.2 With renal complications
0.000 0.490 0.510
E12.1 With ketoacidosis
0.000 0.490 0.510
E12.0 With coma
0.000 0.490 0.510
E03.8 Other specified hypothyroidism
0.000 0.491 0.509
E28.3 Primary ovarian failure
0.000 0.495 0.505
E65-E68 Obesity and other hyperalimentation
0.000 0.496 0.504
E20.9 Hypoparathyroidism, unspecified
0.000 0.505 0.495
E28.9 Ovarian dysfunction, unspecified
0.000 0.512 0.488
E28.8 Other ovarian dysfunction
0.000 0.512 0.488
E28.1 Androgen excess
0.000 0.512 0.488
E28.0 Oestrogen excess
0.000 0.512 0.488
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.513 0.487
E45 Retarded development following protein-energy malnutrition
0.000 0.513 0.487
E43 Unspecified severe protein-energy malnutrition
0.000 0.513 0.487
E42 Marasmic kwashiorkor
0.000 0.513 0.487
E41 Nutritional marasmus
0.000 0.513 0.487
E40 Kwashiorkor
0.000 0.513 0.487
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.515 0.485
E50-E64 Other nutritional deficiencies
0.000 0.520 0.479
E25 Adrenogenital disorders
0.000 0.521 0.479
E27.5 Adrenomedullary hyperfunction
0.000 0.525 0.475
E27.0 Other adrenocortical overactivity
0.000 0.525 0.475
E06.5 Other chronic thyroiditis
0.000 0.527 0.472
E06.4 Drug-induced thyroiditis
0.000 0.527 0.472
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.527 0.472
E06.1 Subacute thyroiditis
0.000 0.527 0.472
E06.0 Acute thyroiditis
0.000 0.527 0.472
E29.9 Testicular dysfunction, unspecified
0.000 0.528 0.472
E29.8 Other testicular dysfunction
0.000 0.528 0.472
E29.0 Testicular hyperfunction
0.000 0.528 0.472
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.529 0.470
E24 Cushing's syndrome
0.000 0.530 0.470
E34.9 Endocrine disorder, unspecified
0.000 0.532 0.468
E06.9 Thyroiditis, unspecified
0.000 0.535 0.465
E26.0 Primary hyperaldosteronism
0.000 0.537 0.463
E34.0 Carcinoid syndrome
0.000 0.542 0.458
E04.8 Other specified non-toxic goitre
0.000 0.542 0.458
E27.2 Addisonian crisis
0.000 0.544 0.456
E46 Unspecified protein-energy malnutrition
0.000 0.545 0.455
E14.8 With unspecified complications
0.000 0.545 0.455
E14.7 With multiple complications
0.000 0.545 0.455
E14.6 With other specified complications
0.000 0.545 0.455
E14.5 With peripheral circulatory complications
0.000 0.545 0.455
E14.2 Withrenal complications
0.000 0.545 0.455
E14.1 With ketoacidosis
0.000 0.545 0.455
E14.0 With coma
0.000 0.545 0.455
E20.8 Other hypoparathyroidism
0.000 0.557 0.443
E20.1 Pseudohypoparathyroidism
0.000 0.557 0.443
E20.0 Idiopathic hypoparathyroidism
0.000 0.557 0.443
E13.8 With unspecified complications
0.000 0.558 0.441
E13.7 With multiple complications
0.000 0.558 0.441
E13.6 With other specified complications
0.000 0.558 0.441
E13.5 With peripheral circulatory complications
0.000 0.558 0.441
E13.4 With neurological complications
0.000 0.558 0.441
E13.3 With ophthalmic complications
0.000 0.558 0.441
E13.2 With renal complications
0.000 0.558 0.441
E13.1 With ketoacidosis
0.000 0.558 0.441
E13.0 With coma
0.000 0.558 0.441
E34.8 Other specified endocrine disorders
0.000 0.561 0.439
E34.5 Androgen resistance syndrome
0.000 0.561 0.439
E34.4 Constitutional tall stature
0.000 0.561 0.439
E34.3 Short stature, not elsewhere classified
0.000 0.561 0.439
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.561 0.439
E34.1 Other hypersecretion of intestinal hormones
0.000 0.561 0.439
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.569 0.431
E26.9 Hyperaldosteronism, unspecified
0.000 0.570 0.430
E26.8 Other hyperaldosteronism
0.000 0.570 0.430
E26.1 Secondary hyperaldosteronism
0.000 0.570 0.430
M07 Psoriatic and enteropathic arthropathies
0.423 0.576 0.001
E06.3 Autoimmune thyroiditis
0.000 0.577 0.423
E14.4 With neurological complications
0.000 0.584 0.415
E22.1 Hyperprolactinaemia
0.000 0.592 0.408
K90 Intestinal malabsorption
0.000 0.592 0.408
E30.9 Disorder of puberty, unspecified
0.000 0.593 0.406
E30.8 Other disorders of puberty
0.000 0.593 0.406
E30.1 Precocious puberty
0.000 0.593 0.406
E30.0 Delayed puberty
0.000 0.593 0.406
E31.9 Polyglandular dysfunction, unspecified
0.000 0.593 0.406
E31.8 Other polyglandular dysfunction
0.000 0.593 0.406
E31.1 Polyglandular hyperfunction
0.000 0.593 0.406
E31.0 Autoimmune polyglandular failure
0.000 0.593 0.406
E32.9 Disease of thymus, unspecified
0.000 0.593 0.406
E32.8 Other diseases of thymus
0.000 0.593 0.406
E32.1 Abscess of thymus
0.000 0.593 0.406
E32.0 Persistent hyperplasia of thymus
0.000 0.593 0.406
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.593 0.406
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.593 0.406
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.593 0.406
E04.0 Non-toxic diffuse goitre
0.000 0.605 0.395
E22.0 Acromegaly and pituitary gigantism
0.000 0.606 0.394
E27.9 Disorder of adrenal gland, unspecified
0.000 0.616 0.384
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.624 0.375
E22.8 Other hyperfunction of pituitary gland
0.000 0.624 0.375
E27.8 Other specified disorders of adrenal gland
0.000 0.629 0.371
E04.1 Non-toxic single thyroid nodule
0.000 0.637 0.363
E67 Other hyperalimentation
0.000 0.638 0.361
E68 Sequelae of hyperalimentation
0.000 0.638 0.361
E65 Localised adiposity
0.000 0.641 0.358
E04.2 Non-toxic multinodular goitre
0.000 0.646 0.354
E44.1 Mild protein-energy malnutrition
0.000 0.651 0.349
E44.0 Moderate protein-energy malnutrition
0.000 0.651 0.349
E13.9 Without complications
0.000 0.654 0.346
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.656 0.344
E63 Other nutritional deficiencies
0.000 0.656 0.344
E56 Other vitamin deficiencies
0.000 0.656 0.344
E51 Thiamine deficiency
0.000 0.656 0.344
E50 Vitamin A deficiency
0.000 0.656 0.344
E60 Dietary zinc deficiency
0.000 0.656 0.344
E59 Dietary selenium deficiency
0.000 0.656 0.344
E58 Dietary calcium deficiency
0.000 0.656 0.344
E54 Ascorbic acid deficiency
0.000 0.656 0.344
E52 Niacin deficiency [pellagra]
0.000 0.656 0.344
E25.9 Adrenogenital disorder, unspecified
0.000 0.656 0.343
E25.8 Other adrenogenital disorders
0.000 0.656 0.343
E61 Deficiency of other nutrient elements
0.000 0.658 0.342
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.662 0.337
E21.4 Other specified disorders of parathyroid gland
0.000 0.662 0.337
E21.2 Other hyperparathyroidism
0.000 0.662 0.337
E24.8 Other Cushing's syndrome
0.000 0.663 0.337
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.663 0.337
E24.3 Ectopic ACTH syndrome
0.000 0.663 0.337
E24.2 Drug-induced Cushing's syndrome
0.000 0.663 0.337
E24.1 Nelson's syndrome
0.000 0.663 0.337
E21.0 Primary hyperparathyroidism
0.000 0.680 0.320
E24.9 Cushing's syndrome, unspecified
0.000 0.685 0.314
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.687 0.312
M07.6 Other enteropathic arthropathies
0.303 0.696 0.001
M07.5 Arthropathy in ulcerative colitis
0.303 0.696 0.001
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.303 0.696 0.001
M07.2 Psoriatic spondylitis
0.303 0.696 0.001
M07.1 Arthritis mutilans
0.303 0.696 0.001
M07.0 Distal interphalangeal psoriatic arthropathy
0.303 0.696 0.001
E23 Hypofunction and other disorders of pituitary gland
0.001 0.699 0.300
E21.3 Hyperparathyroidism, unspecified
0.000 0.700 0.300
E14.9 Without complications
0.000 0.701 0.299
K90.8 Other intestinal malabsorption
0.000 0.707 0.292
K90.3 Pancreatic steatorrhoea
0.000 0.707 0.292
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.707 0.292
K90.1 Tropical sprue
0.000 0.707 0.292
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.719 0.280
K90.9 Intestinal malabsorption, unspecified
0.000 0.721 0.279
E24.0 Pituitary-dependent Cushing's disease
0.001 0.726 0.274
E53 Deficiency of other B group vitamins
0.000 0.732 0.268
L40-L45 Papulosquamous disorders
0.268 0.732 0.000
E67.8 Other specified hyperalimentation
0.000 0.740 0.259
E67.3 Hypervitaminosis D
0.000 0.740 0.259
E67.2 Megavitamin-B6 syndrome
0.000 0.740 0.259
E67.1 Hypercarotenaemia
0.000 0.740 0.259
E67.0 Hypervitaminosis A
0.000 0.740 0.259
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.744 0.255
E55 Vitamin D deficiency
0.000 0.753 0.247
E50.9 Vitamin A deficiency, unspecified
0.000 0.753 0.247
E50.8 Other manifestations of vitamin A deficiency
0.000 0.753 0.247
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.753 0.247
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.753 0.247
E50.5 Vitamin A deficiency with night blindness
0.000 0.753 0.247
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.753 0.247
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.753 0.247
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.753 0.247
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.753 0.247
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.753 0.247
E51.9 Thiamine deficiency, unspecified
0.000 0.753 0.247
E51.8 Other manifestations of thiamine deficiency
0.000 0.753 0.247
E51.2 Wernicke's encephalopathy
0.000 0.753 0.247
E51.1 Beriberi
0.000 0.753 0.247
E56.9 Vitamin deficiency, unspecified
0.000 0.753 0.247
E56.8 Deficiency of other vitamins
0.000 0.753 0.247
E56.1 Deficiency of vitamin K
0.000 0.753 0.247
E56.0 Deficiency of vitamin E
0.000 0.753 0.247
E63.9 Nutritional deficiency, unspecified
0.000 0.753 0.247
E63.8 Other specified nutritional deficiencies
0.000 0.753 0.247
E63.1 Imbalance of constituents of food intake
0.000 0.753 0.247
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.753 0.247
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.753 0.247
E64.8 Sequelae of other nutritional deficiencies
0.000 0.753 0.247
E64.3 Sequelae of rickets
0.000 0.753 0.247
E64.2 Sequelae of vitamin C deficiency
0.000 0.753 0.247
E64.1 Sequelae of vitamin A deficiency
0.000 0.753 0.247
E64.0 Sequelae of protein-energy malnutrition
0.000 0.753 0.247
E61.9 Deficiency of nutrient element, unspecified
0.000 0.755 0.245
E61.8 Deficiency of other specified nutrient elements
0.000 0.755 0.245
E61.7 Deficiency of multiple nutrient elements
0.000 0.755 0.245
E61.6 Vanadium deficiency
0.000 0.755 0.245
E61.5 Molybdenum deficiency
0.000 0.755 0.245
E61.4 Chromium deficiency
0.000 0.755 0.245
E61.3 Manganese deficiency
0.000 0.755 0.245
E61.2 Magnesium deficiency
0.000 0.755 0.245
E61.0 Copper deficiency
0.000 0.755 0.245
E61.1 Iron deficiency
0.000 0.757 0.243
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.757 0.243
E23.2 Diabetes insipidus
0.001 0.766 0.233
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.218 0.782 0.001
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.218 0.782 0.001
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.218 0.782 0.001
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.218 0.782 0.001
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.218 0.782 0.001
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.218 0.782 0.001
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.218 0.782 0.001
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.218 0.782 0.001
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.218 0.782 0.001
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.218 0.782 0.001
M07.19 Arthritis mutilans (Site unspecified)
0.218 0.782 0.001
M07.18 Arthritis mutilans (Other)
0.218 0.782 0.001
M07.17 Arthritis mutilans (Ankle and foot)
0.218 0.782 0.001
M07.16 Arthritis mutilans (Lower leg)
0.218 0.782 0.001
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.218 0.782 0.001
M07.14 Arthritis mutilans (Hand)
0.218 0.782 0.001
M07.13 Arthritis mutilans (Forearm)
0.218 0.782 0.001
M07.12 Arthritis mutilans (Upper arm)
0.218 0.782 0.001
M07.11 Arthritis mutilans (Shoulder region)
0.218 0.782 0.001
M07.10 Arthritis mutilans (Multiple sites)
0.218 0.782 0.001
M07.29 Psoriatic spondylitis (Site unspecified)
0.218 0.782 0.001
M07.28 Psoriatic spondylitis (Other)
0.218 0.782 0.001
M07.27 Psoriatic spondylitis (Ankle and foot)
0.218 0.782 0.001
M07.26 Psoriatic spondylitis (Lower leg)
0.218 0.782 0.001
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.218 0.782 0.001
M07.24 Psoriatic spondylitis (Hand)
0.218 0.782 0.001
M07.23 Psoriatic spondylitis (Forearm)
0.218 0.782 0.001
M07.22 Psoriatic spondylitis (Upper arm)
0.218 0.782 0.001
M07.21 Psoriatic spondylitis (Shoulder region)
0.218 0.782 0.001
M07.20 Psoriatic spondylitis (Multiple sites)
0.218 0.782 0.001
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.218 0.782 0.001
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.218 0.782 0.001
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.218 0.782 0.001
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.218 0.782 0.001
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.218 0.782 0.001
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.218 0.782 0.001
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.218 0.782 0.001
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.218 0.782 0.001
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.218 0.782 0.001
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.218 0.782 0.001
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.218 0.782 0.001
M07.58 Arthropathy in ulcerative colitis (Other)
0.218 0.782 0.001
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.218 0.782 0.001
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.218 0.782 0.001
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.218 0.782 0.001
M07.54 Arthropathy in ulcerative colitis (Hand)
0.218 0.782 0.001
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.218 0.782 0.001
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.218 0.782 0.001
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.218 0.782 0.001
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.218 0.782 0.001
M07.69 Other enteropathic arthropathies (Site unspecified)
0.218 0.782 0.001
M07.68 Other enteropathic arthropathies (Other)
0.218 0.782 0.001
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.218 0.782 0.001
M07.66 Other enteropathic arthropathies (Lower leg)
0.218 0.782 0.001
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.218 0.782 0.001
M07.64 Other enteropathic arthropathies (Hand)
0.218 0.782 0.001
M07.63 Other enteropathic arthropathies (Forearm)
0.218 0.782 0.001
M07.62 Other enteropathic arthropathies (Upper arm)
0.218 0.782 0.001
M07.61 Other enteropathic arthropathies (Shoulder region)
0.218 0.782 0.001
M07.60 Other enteropathic arthropathies (Multiple sites)
0.218 0.782 0.001
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.001 0.784 0.215
E23.1 Drug-induced hypopituitarism
0.001 0.784 0.215
E23.6 Other disorders of pituitary gland
0.001 0.796 0.203
L42 Pityriasis rosea
0.200 0.800 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.807 0.192
E53.1 Pyridoxine deficiency
0.000 0.807 0.192
E53.0 Riboflavin deficiency
0.000 0.807 0.192
L44 Other papulosquamous disorders
0.192 0.808 0.000
L41 Parapsoriasis
0.192 0.808 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.192 0.808 0.000
E55.0 Rickets, active
0.000 0.822 0.177
E66 Obesity
0.000 0.838 0.162
L41.9 Parapsoriasis, unspecified
0.138 0.862 0.000
L41.8 Other parapsoriasis
0.138 0.862 0.000
L41.5 Retiform parapsoriasis
0.138 0.862 0.000
L41.4 Large plaque parapsoriasis
0.138 0.862 0.000
L41.3 Small plaque parapsoriasis
0.138 0.862 0.000
L41.2 Lymphomatoid papulosis
0.138 0.862 0.000
L41.1 Pityriasis lichenoides chronica
0.138 0.862 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.138 0.862 0.000
L44.9 Papulosquamous disorder, unspecified
0.138 0.862 0.000
L44.8 Other specified papulosquamous disorders
0.138 0.862 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.138 0.862 0.000
L44.3 Lichen ruber moniliformis
0.138 0.862 0.000
L44.2 Lichen striatus
0.138 0.862 0.000
L44.1 Lichen nitidus
0.138 0.862 0.000
L44.0 Pityriasis rubra pilaris
0.138 0.862 0.000
E23.7 Disorder of pituitary gland, unspecified
0.001 0.869 0.129
E66.8 Other obesity
0.000 0.880 0.120
K50.0 Crohn's disease of small intestine
0.119 0.881 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.883 0.117
E66.1 Drug-induced obesity
0.000 0.884 0.116
M35.0 Sicca syndrome [Sjogren]
0.000 0.891 0.109
K50 Crohn's disease [regional enteritis]
0.107 0.893 0.000
E23.0 Hypopituitarism
0.001 0.896 0.103
E66.0 Obesity due to excess calories
0.000 0.897 0.103
L43 Lichen planus
0.100 0.899 0.001
M35.3 Polymyalgia rheumatica
0.000 0.900 0.100
M35 Other systemic involvement of connective tissue
0.000 0.900 0.100
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.900 0.100
K50.8 Other Crohn's disease
0.100 0.900 0.000
K50.9 Crohn's disease, unspecified
0.099 0.901 0.000
E55.9 Vitamin D deficiency, unspecified
0.001 0.919 0.080
M35.1 Other overlap syndromes
0.000 0.922 0.078
L43.3 Subacute (active) lichen planus
0.072 0.927 0.001
L43.2 Lichenoid drug reaction
0.072 0.927 0.001
L43.1 Bullous lichen planus
0.072 0.927 0.001
L43.0 Hypertrophic lichen planus
0.072 0.927 0.001
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.928 0.072
M35.8 Other specified systemic involvement of connective tissue
0.000 0.928 0.072
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.928 0.072
M35.5 Multifocal fibrosclerosis
0.000 0.928 0.072
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.928 0.072
M35.2 Behcet's disease
0.000 0.928 0.072
M35.7 Hypermobility syndrome
0.000 0.936 0.064
K90-K93 Other diseases of the digestive system
0.000 0.936 0.064
E11 Non-insulin-dependent diabetes mellitus
0.000 0.937 0.063
K50.1 Crohn's disease of large intestine
0.061 0.939 0.000
L43.8 Other lichen planus
0.057 0.943 0.001
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.948 0.052
H26.9 Cataract, unspecified
0.000 0.948 0.052
K83.1 Obstruction of bile duct
0.051 0.949 0.000
H26 Other cataract
0.000 0.951 0.049
E11.8 With unspecified complications
0.000 0.951 0.049
K83 Other diseases of biliary tract
0.047 0.953 0.000
K83.8 Other specified diseases of biliary tract
0.047 0.953 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.954 0.046
E11.5 With peripheral circulatory complications
0.000 0.954 0.046
H26.4 After-cataract
0.000 0.954 0.046
E11.6 With other specified complications
0.000 0.954 0.046
J33.0 Polyp of nasal cavity
0.000 0.955 0.045
E11.7 With multiple complications
0.000 0.955 0.045
J33 Nasal polyp
0.000 0.956 0.044
H26.8 Other specified cataract
0.000 0.957 0.043
K91.4 Colostomy and enterostomy malfunction
0.000 0.958 0.042
E11.0 With coma
0.000 0.958 0.042
J33.9 Nasal polyp, unspecified
0.000 0.958 0.042
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.958 0.042
H26.2 Complicated cataract
0.000 0.959 0.041
J33.8 Other polyp of sinus
0.000 0.959 0.041
E11.3 With ophthalmic complications
0.000 0.963 0.037
K83.3 Fistula of bile duct
0.037 0.963 0.000
J47 Bronchiectasis
0.000 0.963 0.037
H26.1 Traumatic cataract
0.000 0.964 0.036
H26.0 Infantile, juvenile and presenile cataract
0.000 0.964 0.036
K83.0 Cholangitis
0.036 0.964 0.000
H26.3 Drug-induced cataract
0.000 0.964 0.036
K83.9 Disease of biliary tract, unspecified
0.035 0.965 0.000
K83.5 Biliary cyst
0.034 0.966 0.000
K83.4 Spasm of sphincter of Oddi
0.034 0.966 0.000
K83.2 Perforation of bile duct
0.034 0.966 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.966 0.033
K93.1 Megacolon in Chagas' disease
0.000 0.966 0.033
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.966 0.033
E11.2 With renal complications
0.000 0.967 0.033
E70-E90 Metabolic disorders
0.000 0.967 0.033
J33.1 Polypoid sinus degeneration
0.000 0.969 0.031
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.970 0.029
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.972 0.028
E11.1 With ketoacidosis
0.000 0.972 0.028
E73 Lactose intolerance
0.000 0.972 0.028
K91.5 Postcholecystectomy syndrome
0.000 0.972 0.027
E74 Other disorders of carbohydrate metabolism
0.000 0.975 0.025
E73.9 Lactose intolerance, unspecified
0.000 0.976 0.024
E85 Amyloidosis
0.000 0.976 0.024
E84 Cystic fibrosis
0.000 0.976 0.024
E79 Disorders of purine and pyrimidine metabolism
0.000 0.976 0.024
E77 Disorders of glycoprotein metabolism
0.000 0.976 0.024
E76 Disorders of glycosaminoglycan metabolism
0.000 0.976 0.024
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.976 0.024
E72 Other disorders of amino-acid metabolism
0.000 0.976 0.024
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.976 0.024
E70 Disorders of aromatic amino-acid metabolism
0.000 0.976 0.024
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.976 0.024
L43.9 Lichen planus, unspecified
0.023 0.976 0.001
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.976 0.023
K91.3 Postoperative intestinal obstruction
0.000 0.977 0.022
H25-H28 Disorders of lens
0.000 0.978 0.022
K91.1 Postgastric surgery syndromes
0.001 0.978 0.021
J45.9 Asthma, unspecified
0.000 0.979 0.021
E73.8 Other lactose intolerance
0.000 0.980 0.020
E73.1 Secondary lactase deficiency
0.000 0.980 0.020
E73.0 Congenital lactase deficiency
0.000 0.980 0.020
E83 Disorders of mineral metabolism
0.000 0.980 0.020
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.980 0.020
J45 Asthma
0.000 0.981 0.019
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.981 0.019
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.981 0.019
E85.9 Amyloidosis, unspecified
0.000 0.981 0.019
H27 Other disorders of lens
0.000 0.981 0.019
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.982 0.018
J45.0 Predominantly allergic asthma
0.000 0.982 0.018
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.982 0.018
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.982 0.018
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.982 0.018
E74.2 Disorders of galactose metabolism
0.000 0.982 0.018
E74.1 Disorders of fructose metabolism
0.000 0.982 0.018
E74.0 Glycogen storage disease
0.000 0.982 0.018
E85.8 Other amyloidosis
0.000 0.982 0.017
E85.3 Secondary systemic amyloidosis
0.000 0.982 0.017
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.982 0.017

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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