TreeWAS – Variant ID: rs12193701

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
L40.9 Psoriasis, unspecified	1.000	0.000
L40 Psoriasis	1.000	0.000
# Top node	1.000	0.000
L40-L45 Papulosquamous disorders	0.999	0.001
Chapter XX External causes of morbidity and mortality	0.999	0.001
Chapter XII Diseases of the skin and subcutaneous tissue	0.998	0.002
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.997	0.003
L40.5 Arthropathic psoriasis	0.997	0.003
Chapter XI Diseases of the digestive system	0.986	0.014
K50-K52 Noninfective enteritis and colitis	0.983	0.017
K51 Ulcerative colitis	0.968	0.032
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.966	0.034
K70-K77 Diseases of liver	0.963	0.037
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.960	0.040
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.960	0.040
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.960	0.040
Chapter IV Endocrine, nutritional and metabolic diseases	0.958	0.042
E10-E14 Diabetes mellitus	0.953	0.047
E11 Non-insulin-dependent diabetes mellitus	0.952	0.048
E11.9 Without complications	0.947	0.053
K50 Crohn's disease [regional enteritis]	0.946	0.054
K51.9 Ulcerative colitis, unspecified	0.946	0.054
K76 Other diseases of liver	0.942	0.058
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.919	0.081
M05-M14 Inflammatory polyarthropathies	0.916	0.084
Y43 Primarily systemic agents	0.913	0.087
K76.0 Fatty (change of) liver, not elsewhere classified	0.909	0.091
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.902	0.098
M07 Psoriatic and enteropathic arthropathies	0.891	0.109
T90 Sequelae of injuries of head	0.888	0.112
M45-M49 Spondylopathies	0.880	0.120
Y83.1 Surgical operation with implant of artificial internal device	0.875	0.125
M07.3 Other psoriatic arthropathies	0.873	0.126
E50-E64 Other nutritional deficiencies	0.870	0.130
Y43.3 Other antineoplastic drugs	0.863	0.137
E11.4 With neurological complications	0.859	0.141
T20-T25 Burns and corrosions of external body surface, specified by site	0.858	0.142
L40.0 Psoriasis vulgaris	0.857	0.143
M07.39 Other psoriatic arthropathies (Site unspecified)	0.856	0.144
S90-S99 Injuries to the ankle and foot	0.854	0.146
T66-T78 Other and unspecified effects of external causes	0.850	0.150
K50.0 Crohn's disease of small intestine	0.849	0.151
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.847	0.153
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.847	0.153
K75 Other inflammatory liver diseases	0.843	0.157
K50.9 Crohn's disease, unspecified	0.843	0.157
M70-M79 Other soft tissue disorders	0.840	0.160
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.837	0.163
S80-S89 Injuries to the knee and lower leg	0.835	0.165
K76.9 Liver disease, unspecified	0.834	0.166
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.827	0.172
Chapter V Mental and behavioural disorders	0.826	0.174
Chapter VI Diseases of the nervous system	0.825	0.175
L50-L54 Urticaria and erythema	0.815	0.185
Chapter I Certain infectious and parasitic diseases	0.811	0.189
S00-S09 Injuries to the head	0.807	0.193
T92 Sequelae of injuries of upper limb	0.803	0.197
Q60-Q64 Congenital malformations of the urinary system	0.802	0.198
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.801	0.199
E55 Vitamin D deficiency	0.792	0.208
Y60-Y69 Misadventures to patients during surgical and medical care	0.789	0.211
V40-V49 Car occupant injured in transport accident	0.787	0.213
K51.2 Ulcerative (chronic) proctitis	0.786	0.214
M47 Spondylosis	0.784	0.216
A00-A09 Intestinal infectious diseases	0.784	0.216
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.781	0.219
E11.5 With peripheral circulatory complications	0.780	0.220
Chapter XXII Codes for special purposes	0.779	0.221
Y44 Agents primarily affecting blood constituents	0.777	0.223
M72 Fibroblastic disorders	0.774	0.226
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.774	0.226
Y83.2 Surgical operation with anastomosis, bypass or graft	0.774	0.226
X40-X49 Accidental poisoning by and exposure to noxious substances	0.767	0.232
S80 Superficial injury of lower leg	0.766	0.234
M65-M68 Disorders of synovium and tendon	0.765	0.235
T79-T79 Certain early complications of trauma	0.763	0.237
S91 Open wound of ankle and foot	0.762	0.238
T94 Sequelae of injuries involving multiple and unspecified body regions	0.760	0.240
G90-G99 Other disorders of the nervous system	0.760	0.240
L20-L30 Dermatitis and eczema	0.759	0.241
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.756	0.244
K52 Other non-infective gastro-enteritis and colitis	0.756	0.244
M80-M85 Disorders of bone density and structure	0.755	0.245
S50-S59 Injuries to the elbow and forearm	0.755	0.245
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.755	0.245
K51.0 Ulcerative (chronic) enterocolitis	0.753	0.247
X20-X29 Contact with venomous animals and plants	0.752	0.248
L43 Lichen planus	0.749	0.250
K50.8 Other Crohn's disease	0.749	0.251
K75.0 Abscess of liver	0.749	0.251
M48 Other spondylopathies	0.749	0.251
Y52 Agents primarily affecting the cardiovascular system	0.748	0.252
W20-W49 Exposure to inanimate mechanical forces	0.746	0.254
T58 Toxic effect of carbon monoxide	0.746	0.254
T78 Adverse effects, not elsewhere classified	0.745	0.255
F30-F39 Mood [affective] disorders	0.743	0.257
E11.6 With other specified complications	0.742	0.258
E13 Other specified diabetes mellitus	0.740	0.260
S10-S19 Injuries to the neck	0.740	0.260
E40-E46 Malnutrition	0.740	0.260
K51.3 Ulcerative (chronic) rectosigmoiditis	0.738	0.262
M91-M94 Chondropathies	0.737	0.263
E55.9 Vitamin D deficiency, unspecified	0.737	0.263
T90.2 Sequelae of fracture of skull and facial bones	0.735	0.265
S00 Superficial injury of head	0.730	0.270
T90.4 Sequelae of injury of eye and orbit	0.729	0.270
Q61 Cystic kidney disease	0.728	0.272
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.728	0.272
T15-T19 Effects of foreign body entering through natural orifice	0.727	0.273
Y83.4 Other reconstructive surgery	0.726	0.274
Y42.7 Androgens and anabolic congeners	0.725	0.275
Chapter VIII Diseases of the ear and mastoid process	0.723	0.277
A04 Other bacterial intestinal infections	0.719	0.281
T93 Sequelae of injuries of lower limb	0.718	0.282
L40.8 Other psoriasis	0.717	0.283
L40.4 Guttate psoriasis	0.717	0.283
L40.3 Pustulosis palmaris et plantaris	0.717	0.283
L40.2 Acrodermatitis continua	0.717	0.283
L40.1 Generalised pustular psoriasis	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.717	0.283
L44 Other papulosquamous disorders	0.716	0.284
L41 Parapsoriasis	0.716	0.284
L45 Papulosquamous disorders in diseases classified elsewhere	0.716	0.284
L42 Pityriasis rosea	0.716	0.284
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.716	0.284
Y35-Y36 Legal intervention and operations of war	0.716	0.284
Y10-Y34 Event of undetermined intent	0.716	0.284
Y00-Y09 Assault	0.716	0.284
X85-X99 Assault	0.716	0.284
X58-X59 Accidental exposure to other and unspecified factors	0.716	0.284
X50-X57 Overexertion, travel and privation	0.716	0.284
X30-X39 Exposure to forces of nature	0.716	0.284
X10-X19 Contact with heat and hot substances	0.716	0.284
X00-X09 Exposure to smoke, fire and flames	0.716	0.284
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.716	0.284
W75-W84 Other accidental threats to breathing	0.716	0.284
W65-W74 Accidental drowning and submersion	0.716	0.284
W50-W64 Exposure to animate mechanical forces	0.716	0.284
V98-V99 Other and unspecified transport accidents	0.716	0.284
V95-V97 Air and space transport accidents	0.716	0.284
V90-V94 Water transport accidents	0.716	0.284
V80-V89 Other land transport accidents	0.716	0.284
V70-V79 Bus occupant injured in transport accident	0.716	0.284
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.716	0.284
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.716	0.284
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.716	0.284
V20-V29 Motorcycle rider injured in transport accident	0.716	0.284
V01-V09 Pedestrian injured in transport accident	0.716	0.284
L10-L14 Bullous disorders	0.716	0.284
T33-T35 Frostbite	0.715	0.285
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.285
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.715	0.285
T00-T07 Injuries involving multiple body regions	0.715	0.285
T21 Burn and corrosion of trunk	0.713	0.287
Y43.4 Immunosuppressive agents	0.713	0.287
T90.9 Sequelae of unspecified injury of head	0.712	0.288
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.709	0.291
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.708	0.291
V10-V19 Pedal cyclist injured in transport accident	0.707	0.293
M10 Gout	0.707	0.293
S70-S79 Injuries to the hip and thigh	0.706	0.293
M86-M90 Other osteopathies	0.700	0.299
Chapter II Neoplasms	0.700	0.300
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.700	0.300
W00-W19 Falls	0.700	0.300
T90.5 Sequelae of intracranial injury	0.699	0.301
M07.30 Other psoriatic arthropathies (Multiple sites)	0.698	0.302
S91.3 Open wound of other parts of foot	0.696	0.304
Q80-Q89 Other congenital malformations	0.695	0.305
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.694	0.306
K51.5 Mucosal proctocolitis	0.694	0.306
K51.4 Pseudopolyposis of colon	0.694	0.306
K51.1 Ulcerative (chronic) ileocolitis	0.694	0.306
Q50-Q56 Congenital malformations of genital organs	0.693	0.306
Y59 Other and unspecified vaccines and biological substances	0.692	0.308
Y58 Bacterial vaccines	0.692	0.308
Y57 Other and unspecified drugs and medicaments	0.692	0.308
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.692	0.308
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.692	0.308
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.692	0.308
Y53 Agents primarily affecting the gastro-intestinal system	0.692	0.308
Y50 Central nervous system stimulants, not elsewhere classified	0.692	0.308
Y49 Psychotropic drugs, not elsewhere classified	0.692	0.308
Y48 Anaesthetics and therapeutic gases	0.692	0.308
Y47 Sedatives, hypnotics and antianxiety drugs	0.692	0.308
Y46 Antiepileptics and anti-Parkinsonism drugs	0.692	0.308
Y41 Other systemic anti-infectives and antiparasitics	0.692	0.308
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.692	0.308
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.692	0.308
M79 Other soft tissue disorders, not elsewhere classified	0.691	0.309
K77 Liver disorders in diseases classified elsewhere	0.690	0.310
K73 Chronic hepatitis, not elsewhere classified	0.690	0.310
K71 Toxic liver disease	0.690	0.310
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.690	0.310
M60-M63 Disorders of muscles	0.689	0.311
M00-M03 Infectious arthropathies	0.689	0.311
K50.1 Crohn's disease of large intestine	0.689	0.311
T98 Sequelae of other and unspecified effects of external causes	0.688	0.312
T95 Sequelae of burns, corrosions and frostbite	0.688	0.312
T91 Sequelae of injuries of neck and trunk	0.688	0.312
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.688	0.312
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.688	0.312
M47.2 Other spondylosis with radiculopathy	0.686	0.314
E12 Malnutrition-related diabetes mellitus	0.683	0.317
K83 Other diseases of biliary tract	0.683	0.317
E11.8 With unspecified complications	0.682	0.318
E11.7 With multiple complications	0.682	0.318
E11.1 With ketoacidosis	0.682	0.318
E11.0 With coma	0.682	0.318
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.682	0.318
L53 Other erythematous conditions	0.681	0.319
X60-X84 Intentional self-harm	0.680	0.320
A04.8 Other specified bacterial intestinal infections	0.676	0.324
K76.7 Hepatorenal syndrome	0.675	0.324
K76.5 Hepatic veno-occlusive disease	0.675	0.324
K76.4 Peliosis hepatis	0.675	0.324
K76.3 Infarction of liver	0.675	0.324
K76.2 Central haemorrhagic necrosis of liver	0.675	0.324
K76.1 Chronic passive congestion of liver	0.675	0.324
F32 Depressive episode	0.675	0.325
S80.9 Superficial injury of lower leg, unspecified	0.672	0.328
Y51 Drugs primarily affecting the autonomic nervous system	0.672	0.328
G93 Other disorders of brain	0.672	0.328
M47.9 Spondylosis, unspecified	0.671	0.329
E11.2 With renal complications	0.671	0.329
K76.8 Other specified diseases of liver	0.670	0.330
Y85 Sequelae of transport accidents	0.669	0.331
A09.9 Gastroenteritis and colitis of unspecified origin	0.669	0.331
M06 Other rheumatoid arthritis	0.669	0.331
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.668	0.332
T78.4 Allergy, unspecified	0.663	0.337
S02 Fracture of skull and facial bones	0.662	0.337
K72 Hepatic failure, not elsewhere classified	0.662	0.338
Y83.5 Amputation of limb(s)	0.659	0.341
C34 Malignant neoplasm of bronchus and lung	0.659	0.341
M65 Synovitis and tenosynovitis	0.657	0.343
Y40 Systemic antibiotics	0.657	0.343
T84.0 Mechanical complication of internal joint prosthesis	0.657	0.343
M14 Arthropathies in other diseases classified elsewhere	0.656	0.343
M12 Other specific arthropathies	0.656	0.343
M09 Juvenile arthritis in diseases classified elsewhere	0.656	0.343
M08 Juvenile arthritis	0.656	0.343
T92.2 Sequelae of fracture at wrist and hand level	0.656	0.343
Y83.8 Other surgical procedures	0.656	0.344
S20-S29 Injuries to the thorax	0.655	0.345
E61 Deficiency of other nutrient elements	0.655	0.345
Y83.0 Surgical operation with transplant of whole organ	0.655	0.345
Y43.9 Primarily systemic agent, unspecified	0.654	0.346
Y43.8 Other primarily systemic agents, not elsewhere classified	0.654	0.346
Y43.6 Enzymes, not elsewhere classified	0.654	0.346
Y43.5 Acidifying and alkalising agents	0.654	0.346
Y43.2 Antineoplastic natural products	0.654	0.346
Y43.1 Antineoplastic antimetabolites	0.654	0.346
Y43.0 Antiallergic and antiemetic drugs	0.654	0.346
T63 Toxic effect of contact with venomous animals	0.654	0.346
M48.0 Spinal stenosis	0.654	0.346
F60-F69 Disorders of adult personality and behaviour	0.652	0.348
K76.6 Portal hypertension	0.651	0.349
E14 Unspecified diabetes mellitus	0.650	0.349
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.650	0.350
K86 Other diseases of pancreas	0.650	0.350
K51.8 Other ulcerative colitis	0.649	0.351
A80-A89 Viral infections of the central nervous system	0.649	0.351
S86 Injury of muscle and tendon at lower leg level	0.648	0.351
M46 Other inflammatory spondylopathies	0.648	0.351
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.647	0.353
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.647	0.353
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.647	0.353
Q38-Q45 Other congenital malformations of the digestive system	0.647	0.353
Q35-Q37 Cleft lip and cleft palate	0.647	0.353
Q30-Q34 Congenital malformations of the respiratory system	0.647	0.353
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.647	0.353
Q00-Q07 Congenital malformations of the nervous system	0.647	0.353
G20-G26 Extrapyramidal and movement disorders	0.643	0.357
Y44.2 Anticoagulants	0.642	0.358
E53 Deficiency of other B group vitamins	0.641	0.359
M07.6 Other enteropathic arthropathies	0.639	0.361
M07.5 Arthropathy in ulcerative colitis	0.639	0.361
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.639	0.361
M07.2 Psoriatic spondylitis	0.639	0.361
M07.1 Arthritis mutilans	0.639	0.361
M07.0 Distal interphalangeal psoriatic arthropathy	0.639	0.361
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.638	0.362
M76 Enthesopathies of lower limb, excluding foot	0.638	0.362
L28 Lichen simplex chronicus and prurigo	0.638	0.362
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.638	0.362
T90.8 Sequelae of other specified injuries of head	0.637	0.363
T90.3 Sequelae of injury of cranial nerves	0.637	0.363
T90.1 Sequelae of open wound of head	0.637	0.363
T90.0 Sequelae of superficial injury of head	0.637	0.363
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.636	0.364
V48 Car occupant injured in noncollision transport accident	0.635	0.365
Y83.6 Removal of other organ (partial) (total)	0.634	0.366
M47.99 Spondylosis, unspecified (Site unspecified)	0.633	0.367
S00.9 Superficial injury of head, part unspecified	0.632	0.368
M49 Spondylopathies in diseases classified elsewhere	0.631	0.369
Y83.9 Surgical procedure, unspecified	0.631	0.369
Q20-Q28 Congenital malformations of the circulatory system	0.631	0.369
G30-G32 Other degenerative diseases of the nervous system	0.630	0.370
S40-S49 Injuries to the shoulder and upper arm	0.630	0.370
Y84.0 Cardiac catheterisation	0.630	0.370
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.628	0.372
Y88 Sequelae of surgical and medical care as external cause	0.628	0.372
M11 Other crystal arthropathies	0.627	0.372
S81 Open wound of lower leg	0.627	0.373
F32.9 Depressive episode, unspecified	0.627	0.373
M71 Other bursopathies	0.627	0.373
Y91 Evidence of alcohol involvement determined by level of intoxication	0.627	0.373
M07.38 Other psoriatic arthropathies (Other)	0.626	0.374
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.626	0.374
M07.36 Other psoriatic arthropathies (Lower leg)	0.626	0.374
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.626	0.374
M07.34 Other psoriatic arthropathies (Hand)	0.626	0.374
M07.33 Other psoriatic arthropathies (Forearm)	0.626	0.374
M07.32 Other psoriatic arthropathies (Upper arm)	0.626	0.374
M07.31 Other psoriatic arthropathies (Shoulder region)	0.626	0.374
S80.8 Other superficial injuries of lower leg	0.626	0.374
S50 Superficial injury of forearm	0.624	0.376
E64 Sequelae of malnutrition and other nutritional deficiencies	0.624	0.376
E63 Other nutritional deficiencies	0.624	0.376
E56 Other vitamin deficiencies	0.624	0.376
E51 Thiamine deficiency	0.624	0.376
E50 Vitamin A deficiency	0.624	0.376
E60 Dietary zinc deficiency	0.624	0.376
E59 Dietary selenium deficiency	0.624	0.376
E58 Dietary calcium deficiency	0.624	0.376
E54 Ascorbic acid deficiency	0.624	0.376
E52 Niacin deficiency [pellagra]	0.624	0.376
F00-F09 Organic, including symptomatic, mental disorders	0.623	0.377
M70 Soft tissue disorders related to use, overuse and pressure	0.623	0.377
Y84.6 Urinary catheterisation	0.622	0.378
G00-G09 Inflammatory diseases of the central nervous system	0.621	0.379
K75.8 Other specified inflammatory liver diseases	0.619	0.381
G94 Other disorders of brain in diseases classified elsewhere	0.618	0.381
T83.0 Mechanical complication of urinary (indwelling) catheter	0.618	0.382
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.617	0.382
G80-G83 Cerebral palsy and other paralytic syndromes	0.617	0.383
T94.1 Sequelae of injuries, not specified by body region	0.617	0.383
M40-M43 Deforming dorsopathies	0.616	0.384
K74 Fibrosis and cirrhosis of liver	0.616	0.384
T25 Burn and corrosion of ankle and foot	0.615	0.384
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.615	0.384
T23 Burn and corrosion of wrist and hand	0.615	0.384
T20 Burn and corrosion of head and neck	0.615	0.384
K52.3 Indeterminate colitis	0.615	0.384
Y86 Sequelae of other accidents	0.614	0.386
K52.8 Other specified non-infective gastro-enteritis and colitis	0.614	0.386
D37-D48 Neoplasms of uncertain or unknown behaviour	0.614	0.386
K75.9 Inflammatory liver disease, unspecified	0.614	0.386
K85 Acute pancreatitis	0.614	0.386
K70 Alcoholic liver disease	0.613	0.387
S99 Other and unspecified injuries of ankle and foot	0.612	0.387
S98 Traumatic amputation of ankle and foot	0.612	0.387
S97 Crushing injury of ankle and foot	0.612	0.387
S96 Injury of muscle and tendon at ankle and foot level	0.612	0.387
S95 Injury of blood vessels at ankle and foot level	0.612	0.387
S94 Injury of nerves at ankle and foot level	0.612	0.387
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.612	0.387
S90 Superficial injury of ankle and foot	0.612	0.387
C34.9 Bronchus or lung, unspecified	0.612	0.388
M05 Seropositive rheumatoid arthritis	0.610	0.390
T75 Effects of other external causes	0.609	0.390
T74 Maltreatment syndromes	0.609	0.390
T73 Effects of other deprivation	0.609	0.390
T70 Effects of air pressure and water pressure	0.609	0.390
T69 Other effects of reduced temperature	0.609	0.390
T67 Effects of heat and light	0.609	0.390
T71 Asphyxiation	0.609	0.390
T68 Hypothermia	0.609	0.390
T66 Unspecified effects of radiation	0.609	0.390
T21.2 Burn of second degree of trunk	0.609	0.391
F33 Recurrent depressive disorder	0.608	0.392
T87 Complications peculiar to reattachment and amputation	0.608	0.392
T86 Failure and rejection of transplanted organs and tissues	0.608	0.392
T80 Complications following infusion, transfusion and therapeutic injection	0.608	0.392
T65 Toxic effect of other and unspecified substances	0.607	0.393
T62 Toxic effect of other noxious substances eaten as food	0.607	0.393
T61 Toxic effect of noxious substances eaten as seafood	0.607	0.393
T60 Toxic effect of pesticides	0.607	0.393
T59 Toxic effect of other gases, fumes and vapours	0.607	0.393
T57 Toxic effect of other inorganic substances	0.607	0.393
T56 Toxic effect of metals	0.607	0.393
T54 Toxic effect of corrosive substances	0.607	0.393
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.607	0.393
T52 Toxic effect of organic solvents	0.607	0.393
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.607	0.393
T55 Toxic effect of soaps and detergents	0.607	0.393
S02.6 Fracture of mandible	0.606	0.393
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.605	0.395
K75.4 Autoimmune hepatitis	0.605	0.395
K75.3 Granulomatous hepatitis, not elsewhere classified	0.605	0.395
K75.2 Nonspecific reactive hepatitis	0.605	0.395
K75.1 Phlebitis of portal vein	0.605	0.395
M73 Soft tissue disorders in diseases classified elsewhere	0.602	0.398
Y84.2 Radiological procedure and radiotherapy	0.602	0.398
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.602	0.398
B90-B94 Sequelae of infectious and parasitic diseases	0.602	0.398
K35-K38 Diseases of appendix	0.600	0.399
M65.3 Trigger finger	0.600	0.400
Y42.9 Other and unspecified hormone antagonists	0.600	0.400
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.600	0.400
Y42.4 Oral contraceptives	0.600	0.400
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.600	0.400
Y42.2 Antithyroid drugs	0.600	0.400
Y42.1 Thyroid hormones and substitutes	0.600	0.400
Y42.0 Glucocorticoids and synthetic analogs	0.600	0.400
Q61.3 Polycystic kidney, unspecified	0.600	0.400
S89 Other and unspecified injuries of lower leg	0.600	0.400
K52.0 Gastro-enteritis and colitis due to radiation	0.599	0.400
S88 Traumatic amputation of lower leg	0.599	0.401
S87 Crushing injury of lower leg	0.599	0.401
S85 Injury of blood vessels at lower leg level	0.599	0.401
S84 Injury of nerves at lower leg level	0.599	0.401
G90 Disorders of autonomic nervous system	0.599	0.401
F80-F89 Disorders of psychological development	0.599	0.401
T84.1 Mechanical complication of internal fixation device of bones of limb	0.597	0.403
Q61.2 Polycystic kidney, adult type	0.597	0.403
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.596	0.404
Q61.0 Congenital single renal cyst	0.596	0.404
T79 Certain early complications of trauma, not elsewhere classified	0.595	0.405
G61 Inflammatory polyneuropathy	0.594	0.406
Y89 Sequelae of other external causes	0.593	0.407
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.593	0.407
M48.07 Spinal stenosis (Lumbosacral region)	0.592	0.408
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.592	0.408
F70-F79 Mental retardation	0.592	0.408
K83.1 Obstruction of bile duct	0.592	0.408
W44 Foreign body entering into or through eye or natural orifice	0.591	0.409
E20-E35 Disorders of other endocrine glands	0.590	0.410
L50 Urticaria	0.590	0.410
Y83.3 Surgical operation with formation of external stoma	0.589	0.411
F99-F99 Unspecified mental disorder	0.587	0.412
E13.9 Without complications	0.587	0.413
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.586	0.414
S92 Fracture of foot, except ankle	0.586	0.414
K81 Cholecystitis	0.586	0.414
S80.1 Contusion of other and unspecified parts of lower leg	0.586	0.414
L53.9 Erythematous condition, unspecified	0.585	0.415
L54 Erythema in diseases classified elsewhere	0.585	0.415
L51 Erythema multiforme	0.585	0.415
L52 Erythema nodosum	0.585	0.415
M80 Osteoporosis with pathological fracture	0.585	0.415
M13 Other arthritis	0.584	0.416
D00-D09 In situ neoplasms	0.584	0.416
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.583	0.417
S00.3 Superficial injury of nose	0.583	0.417
E46 Unspecified protein-energy malnutrition	0.583	0.417
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.582	0.418
B99-B99 Other infectious diseases	0.581	0.419
B85-B89 Pediculosis, acariasis and other infestations	0.581	0.419
B65-B83 Helminthiases	0.581	0.419
B50-B64 Protozoal diseases	0.581	0.419
B20-B24 Human immunodeficiency virus [HIV] disease	0.581	0.419
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.581	0.419
A75-A79 Rickettsioses	0.581	0.419
A70-A74 Other diseases caused by chlamydiae	0.581	0.419
A65-A69 Other spirochaetal diseases	0.581	0.419
A20-A28 Certain zoonotic bacterial diseases	0.581	0.419
A15-A19 Tuberculosis	0.581	0.419
S51 Open wound of forearm	0.581	0.419
Q63 Other congenital malformations of kidney	0.581	0.419
S06 Intracranial injury	0.580	0.420
D50-D53 Nutritional anaemias	0.580	0.420
M45 Ankylosing spondylitis	0.579	0.420
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.580	0.420
S08 Traumatic amputation of part of head	0.579	0.421
S07 Crushing injury of head	0.579	0.421
S05 Injury of eye and orbit	0.579	0.421
S04 Injury of cranial nerves	0.579	0.421
S03 Dislocation, sprain and strain of joints and ligaments of head	0.579	0.421
T78.3 Angioneurotic oedema	0.579	0.421
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.578	0.422
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.578	0.422
M94 Other disorders of cartilage	0.577	0.423
T92.9 Sequelae of unspecified injury of upper limb	0.576	0.424
T92.8 Sequelae of other specified injuries of upper limb	0.576	0.424
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.576	0.424
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.576	0.424
T92.4 Sequelae of injury of nerve of upper limb	0.576	0.424
T92.0 Sequelae of open wound of upper limb	0.576	0.424
M77 Other enthesopathies	0.576	0.424
X23 Contact with hornets, wasps and bees	0.575	0.425
Q64 Other congenital malformations of urinary system	0.575	0.425
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.575	0.425
Q60 Renal agenesis and other reduction defects of kidney	0.575	0.425
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.575	0.425
G63 Polyneuropathy in diseases classified elsewhere	0.574	0.426
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.573	0.427
G93.1 Anoxic brain damage, not elsewhere classified	0.573	0.427
Y52.3 Coronary vasodilators, not elsewhere classified	0.572	0.428
G91 Hydrocephalus	0.571	0.429
K82 Other diseases of gallbladder	0.571	0.429
L43.9 Lichen planus, unspecified	0.570	0.429
C32 Malignant neoplasm of larynx	0.570	0.430
L30 Other dermatitis	0.570	0.430
M84 Disorders of continuity of bone	0.568	0.432
E55.0 Rickets, active	0.568	0.432
G70-G73 Diseases of myoneural junction and muscle	0.568	0.432
K90-K93 Other diseases of the digestive system	0.567	0.433

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations