TreeWAS – Variant ID: rs12195036

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
M20-M25 Other joint disorders	0.135	0.865
M35 Other systemic involvement of connective tissue	0.134	0.866
M35.3 Polymyalgia rheumatica	0.134	0.866
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.133	0.867
M22 Disorders of patella	0.127	0.873
M45-M49 Spondylopathies	0.122	0.878
M31 Other necrotising vasculopathies	0.122	0.878
M05-M14 Inflammatory polyarthropathies	0.121	0.879
M80-M85 Disorders of bone density and structure	0.119	0.881
M91-M94 Chondropathies	0.117	0.883
M11 Other crystal arthropathies	0.114	0.886
M35.7 Hypermobility syndrome	0.114	0.886
M45 Ankylosing spondylitis	0.114	0.886
M22.4 Chondromalacia patellae	0.114	0.886
M21 Other acquired deformities of limbs	0.111	0.889
M11.2 Other chondrocalcinosis	0.110	0.890
M07 Psoriatic and enteropathic arthropathies	0.110	0.890
M31.6 Other giant cell arteritis	0.109	0.891
M50-M54 Other dorsopathies	0.109	0.891
M86-M90 Other osteopathies	0.109	0.891
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.108	0.892
M11.26 Other chondrocalcinosis (Lower leg)	0.108	0.892
M45.X9 Ankylosing spondylitis (Site unspecified)	0.106	0.893
M22.2 Patellofemoral disorders	0.103	0.896
M34 Systemic sclerosis	0.103	0.897
M07.3 Other psoriatic arthropathies	0.103	0.897
M54 Dorsalgia	0.102	0.898
M22.8 Other disorders of patella	0.101	0.899
M24 Other specific joint derangements	0.101	0.899
M00-M03 Infectious arthropathies	0.101	0.899
M33 Dermatopolymyositis	0.100	0.900
M93 Other osteochondropathies	0.099	0.901
M54.3 Sciatica	0.099	0.901
M85 Other disorders of bone density and structure	0.099	0.901
M54.39 Sciatica (Site unspecified)	0.097	0.903
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.097	0.903
M32 Systemic lupus erythematosus	0.097	0.903
M30 Polyarteritis nodosa and related conditions	0.097	0.903
M65-M68 Disorders of synovium and tendon	0.096	0.904
M35.9 Systemic involvement of connective tissue, unspecified	0.096	0.904
M35.8 Other specified systemic involvement of connective tissue	0.096	0.904
M35.6 Relapsing panniculitis [Weber-Christian]	0.096	0.904
M35.5 Multifocal fibrosclerosis	0.096	0.904
M35.4 Diffuse (eosinophilic) fasciitis	0.096	0.904
M35.2 Behcet's disease	0.096	0.904
M35.1 Other overlap syndromes	0.096	0.904
M21.1 Varus deformity, not elsewhere classified	0.096	0.904
M80 Osteoporosis with pathological fracture	0.096	0.904
M46 Other inflammatory spondylopathies	0.096	0.904
M94 Other disorders of cartilage	0.096	0.904
M89 Other disorders of bone	0.095	0.905
M22.3 Other derangements of patella	0.095	0.905
M60-M63 Disorders of muscles	0.094	0.906
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.094	0.906
M07.39 Other psoriatic arthropathies (Site unspecified)	0.093	0.907
M47 Spondylosis	0.093	0.907
M22.1 Recurrent subluxation of patella	0.091	0.909
M22.9 Disorder of patella, unspecified	0.091	0.909
M22.0 Recurrent dislocation of patella	0.091	0.909
M81 Osteoporosis without pathological fracture	0.091	0.909
M84 Disorders of continuity of bone	0.091	0.909
M31.3 Wegener's granulomatosis	0.090	0.910
M49 Spondylopathies in diseases classified elsewhere	0.089	0.911
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.089	0.911
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.088	0.911
M31.9 Necrotising vasculopathy, unspecified	0.087	0.912
M31.8 Other specified necrotising vasculopathies	0.087	0.912
M31.7 Microscopic polyangiitis	0.087	0.912
M31.4 Aortic arch syndrome [Takayasu]	0.087	0.912
M31.2 Lethal midline granuloma	0.087	0.912
M31.1 Thrombotic microangiopathy	0.087	0.912
M31.0 Hypersensitivity angiitis	0.087	0.912
M14 Arthropathies in other diseases classified elsewhere	0.087	0.913
M12 Other specific arthropathies	0.087	0.913
M09 Juvenile arthritis in diseases classified elsewhere	0.087	0.913
M08 Juvenile arthritis	0.087	0.913
M93.9 Osteochondropathy, unspecified	0.086	0.914
M83 Adult osteomalacia	0.086	0.914
M82 Osteoporosis in diseases classified elsewhere	0.085	0.915
M89.8 Other specified disorders of bone	0.085	0.915
M92 Other juvenile osteochondrosis	0.084	0.915
M21.2 Flexion deformity	0.084	0.915
M85.8 Other specified disorders of bone density and structure	0.084	0.916
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.084	0.916
M91 Juvenile osteochondrosis of hip and pelvis	0.084	0.916
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.083	0.916
M07.30 Other psoriatic arthropathies (Multiple sites)	0.083	0.917
M65 Synovitis and tenosynovitis	0.083	0.917
M34.9 Systemic sclerosis, unspecified	0.083	0.917
M11.9 Crystal arthropathy, unspecified	0.082	0.918
M11.8 Other specified crystal arthropathies	0.082	0.918
M11.1 Familial chondrocalcinosis	0.082	0.918
M11.0 Hydroxyapatite deposition disease	0.082	0.918
M24.0 Loose body in joint	0.082	0.918
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.082	0.918
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.082	0.918
M45.X6 Ankylosing spondylitis (Lumbar region)	0.082	0.918
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.082	0.918
M45.X4 Ankylosing spondylitis (Thoracic region)	0.082	0.918
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.082	0.918
M45.X2 Ankylosing spondylitis (Cervical region)	0.082	0.918
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.082	0.918
M54.9 Dorsalgia, unspecified	0.082	0.918
M21.3 Wrist or foot drop (acquired)	0.081	0.918
M86 Osteomyelitis	0.081	0.918
M23 Internal derangement of knee	0.081	0.919
M94.8 Other specified disorders of cartilage	0.080	0.920
M54.1 Radiculopathy	0.080	0.920
M07.36 Other psoriatic arthropathies (Lower leg)	0.080	0.920
M21.9 Acquired deformity of limb, unspecified	0.080	0.920
M21.8 Other specified acquired deformities of limbs	0.080	0.920
M21.7 Unequal limb length (acquired)	0.080	0.920
M21.6 Other acquired deformities of ankle and foot	0.080	0.920
M21.4 Flat foot [pes planus] (acquired)	0.080	0.920
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.079	0.920
M05 Seropositive rheumatoid arthritis	0.079	0.920
M53 Other dorsopathies, not elsewhere classified	0.079	0.920
M11.29 Other chondrocalcinosis (Site unspecified)	0.079	0.921
M11.28 Other chondrocalcinosis (Other)	0.079	0.921
M11.27 Other chondrocalcinosis (Ankle and foot)	0.079	0.921
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.079	0.921
M11.24 Other chondrocalcinosis (Hand)	0.079	0.921
M11.23 Other chondrocalcinosis (Forearm)	0.079	0.921
M11.22 Other chondrocalcinosis (Upper arm)	0.079	0.921
M11.21 Other chondrocalcinosis (Shoulder region)	0.079	0.921
M11.20 Other chondrocalcinosis (Multiple sites)	0.079	0.921
M07.6 Other enteropathic arthropathies	0.079	0.921
M07.5 Arthropathy in ulcerative colitis	0.079	0.921
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.079	0.921
M07.2 Psoriatic spondylitis	0.079	0.921
M07.1 Arthritis mutilans	0.079	0.921
M07.0 Distal interphalangeal psoriatic arthropathy	0.079	0.921
M81.4 Drug-induced osteoporosis	0.079	0.921
M99 Biomechanical lesions, not elsewhere classified	0.078	0.922
M40-M43 Deforming dorsopathies	0.077	0.923
M00 Pyogenic arthritis	0.077	0.923
M46.9 Inflammatory spondylopathy, unspecified	0.077	0.923
M24.2 Disorder of ligament	0.077	0.923
M47.2 Other spondylosis with radiculopathy	0.077	0.923
M90 Osteopathies in diseases classified elsewhere	0.077	0.923
M47.9 Spondylosis, unspecified	0.077	0.923
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.077	0.923
M54.6 Pain in thoracic spine	0.076	0.924
M15-M19 Arthrosis	0.076	0.924
M33.1 Other dermatomyositis	0.075	0.925
M54.37 Sciatica (Lumbosacral region)	0.074	0.925
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.074	0.925
M54.96 Dorsalgia, unspecified (Lumbar region)	0.074	0.926
M34.8 Other forms of systemic sclerosis	0.074	0.926
M34.2 Systemic sclerosis induced by drugs and chemicals	0.074	0.926
M34.0 Progressive systemic sclerosis	0.074	0.926
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.074	0.926
M07.38 Other psoriatic arthropathies (Other)	0.074	0.926
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.074	0.926
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.074	0.926
M07.34 Other psoriatic arthropathies (Hand)	0.074	0.926
M07.33 Other psoriatic arthropathies (Forearm)	0.074	0.926
M07.32 Other psoriatic arthropathies (Upper arm)	0.074	0.926
M07.31 Other psoriatic arthropathies (Shoulder region)	0.074	0.926
M23.4 Loose body in knee	0.073	0.927
M54.8 Other dorsalgia	0.073	0.927
M54.0 Panniculitis affecting regions of neck and back	0.073	0.927
M96.8 Other postprocedural musculoskeletal disorders	0.073	0.927
M06 Other rheumatoid arthritis	0.073	0.927
M88 Paget's disease of bone [osteitis deformans]	0.073	0.927
M50 Cervical disk disorders	0.073	0.927
M24.9 Joint derangement, unspecified	0.072	0.927
M24.7 Protrusio acetabuli	0.072	0.927
M24.6 Ankylosis of joint	0.072	0.927
M24.5 Contracture of joint	0.072	0.927
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.072	0.927
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.072	0.928
M02 Reactive arthropathies	0.072	0.928
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.072	0.928
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.072	0.928
M54.16 Radiculopathy (Lumbar region)	0.072	0.928
M24.8 Other specific joint derangements, not elsewhere classified	0.072	0.928
M87 Osteonecrosis	0.072	0.928
M85.6 Other cyst of bone	0.072	0.928
M54.4 Lumbago with sciatica	0.072	0.928
M33.9 Dermatopolymyositis, unspecified	0.072	0.928
M33.2 Polymyositis	0.072	0.928
M33.0 Juvenile dermatomyositis	0.072	0.928
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.072	0.928
M80.5 Idiopathic osteoporosis with pathological fracture	0.072	0.928
M13 Other arthritis	0.071	0.929
M93.8 Other specified osteochondropathies	0.071	0.929
M93.2 Osteochondritis dissecans	0.071	0.929
M93.1 Kienbock's disease of adults	0.071	0.929
M93.0 Slipped upper femoral epiphysis (nontraumatic)	0.071	0.929
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.071	0.929
M54.35 Sciatica (Thoracolumbar region)	0.071	0.929
M54.34 Sciatica-Thoracic	0.071	0.929
M54.33 Sciatica-Cervicothoracic	0.071	0.929
M54.32 Sciatica-Cervical	0.071	0.929
M54.31 Sciatica-Occipit-atl-axl	0.071	0.929
M54.30 Sciatica (Multiple sites in spine)	0.071	0.929
M48 Other spondylopathies	0.071	0.929
M85.9 Disorder of bone density and structure, unspecified	0.071	0.929
M85.5 Aneurysmal bone cyst	0.071	0.929
M85.4 Solitary bone cyst	0.071	0.929
M85.3 Osteitis condensans	0.071	0.929
M85.2 Hyperostosis of skull	0.071	0.929
M85.1 Skeletal fluorosis	0.071	0.929
M34.1 CR(E)ST syndrome	0.071	0.929
M89.81 Other specified disorders of bone (Shoulder region)	0.071	0.929
M84.1 Nonunion of fracture [pseudarthrosis]	0.071	0.929
M81.40 Drug-induced osteoporosis (Multiple sites)	0.071	0.929
M65.9 Synovitis and tenosynovitis, unspecified	0.070	0.930
M30.8 Other conditions related to polyarteritis nodosa	0.070	0.930
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.070	0.930
M30.2 Juvenile polyarteritis	0.070	0.930
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.070	0.930
M30.0 Polyarteritis nodosa	0.070	0.930
M32.9 Systemic lupus erythematosus, unspecified	0.070	0.930
M32.8 Other forms of systemic lupus erythematosus	0.070	0.930
M32.1 Systemic lupus erythematosus with organ or system involvement	0.070	0.930
M32.0 Drug-induced systemic lupus erythematosus	0.070	0.930
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.070	0.930
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.070	0.930
M36.3 Arthropathy in other blood disorders	0.070	0.930
M36.2 Haemophilic arthropathy	0.070	0.930
M36.1 Arthropathy in neoplastic disease	0.070	0.930
M36.0 Dermato(poly)myositis in neoplastic disease	0.070	0.930
M89.9 Disorder of bone, unspecified	0.070	0.930
M21.0 Valgus deformity, not elsewhere classified	0.069	0.930
M85.0 Fibrous dysplasia (monostotic)	0.069	0.931
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.069	0.931
M94.2 Chondromalacia	0.069	0.931
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.069	0.931
M21.18 Varus deformity, not elsewhere classified (Other)	0.069	0.931
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.069	0.931
M21.14 Varus deformity, not elsewhere classified (Hand)	0.069	0.931
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.069	0.931
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.069	0.931
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.069	0.931
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.069	0.931
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.069	0.931
M80.8 Other osteoporosis with pathological fracture	0.069	0.931
M80.4 Drug-induced osteoporosis with pathological fracture	0.069	0.931
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.069	0.931
M80.2 Osteoporosis of disuse with pathological fracture	0.069	0.931
M94.86 Other specified disorders of cartilage (Lower leg)	0.069	0.931
M46.8 Other specified inflammatory spondylopathies	0.069	0.931
M46.5 Other infective spondylopathies	0.069	0.931
M46.4 Discitis, unspecified	0.069	0.931
M46.3 Infection of intervertebral disk (pyogenic)	0.069	0.931
M46.2 Osteomyelitis of vertebra	0.069	0.931
M46.1 Sacro-iliitis, not elsewhere classified	0.069	0.931
M46.0 Spinal enthesopathy	0.069	0.931
M94.9 Disorder of cartilage, unspecified	0.069	0.931
M94.3 Chondrolysis	0.069	0.931
M94.1 Relapsing polychondritis	0.069	0.931
M94.0 Chondrocostal junction syndrome [Tietze]	0.069	0.931
M54.36 Sciatica (Lumbar region)	0.069	0.931
M24.01 Loose body in joint (Shoulder region)	0.068	0.931
M89.6 Osteopathy after poliomyelitis	0.068	0.932
M89.5 Osteolysis	0.068	0.932
M89.4 Other hypertrophic osteo-arthropathy	0.068	0.932
M89.3 Hypertrophy of bone	0.068	0.932
M89.2 Other disorders of bone development and growth	0.068	0.932
M89.1 Epiphyseal arrest	0.068	0.932
M89.0 Algoneurodystrophy	0.068	0.932
M96.0 Pseudarthrosis after fusion or arthrodesis	0.068	0.932
M23.49 Loose body in knee-Unspec lig/men	0.068	0.932
M89.87 Other specified disorders of bone (Ankle and foot)	0.068	0.932
M63 Disorders of muscle in diseases classified elsewhere	0.068	0.932
M61 Calcification and ossification of muscle	0.068	0.932
M60 Myositis	0.068	0.932
M24.4 Recurrent dislocation and subluxation of joint	0.068	0.932
M65.8 Other synovitis and tenosynovitis	0.068	0.932
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.068	0.932
M35.0 Sicca syndrome [Sjogren]	0.067	0.932
M89.86 Other specified disorders of bone (Lower leg)	0.067	0.933
M47.0 Anterior spinal and vertebral artery compression syndromes	0.067	0.933
M84.0 Malunion of fracture	0.066	0.934
M62 Other disorders of muscle	0.066	0.934
M66 Spontaneous rupture of synovium and tendon	0.066	0.934
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.066	0.934
M17 Gonarthrosis [arthrosis of knee]	0.066	0.934
M54.5 Low back pain	0.066	0.934
M22.10 Recurrent subluxation of patella, unspecified knee	0.066	0.934
M81.8 Other osteoporosis	0.066	0.934
M81.6 Localised osteoporosis [Lequesne]	0.066	0.934
M81.5 Idiopathic osteoporosis	0.066	0.934
M81.3 Postsurgical malabsorption osteoporosis	0.066	0.934
M81.2 Osteoporosis of disuse	0.066	0.934
M81.1 Postoophorectomy osteoporosis	0.066	0.934
M81.0 Postmenopausal osteoporosis	0.066	0.934
M84.9 Disorder of continuity of bone, unspecified	0.066	0.934
M84.8 Other disorders of continuity of bone	0.066	0.934
M84.4 Pathological fracture, not elsewhere classified	0.066	0.934
M84.3 Stress fracture, not elsewhere classified	0.066	0.934
M84.2 Delayed union of fracture	0.066	0.934
M80.9 Unspecified osteoporosis with pathological fracture	0.065	0.934
M23.5 Chronic instability of knee	0.065	0.934
M21.24 Flexion deformity (Hand)	0.065	0.934
M54.94 Dorsalgia, unspecified (Thoracic region)	0.065	0.935
M49.5 Collapsed vertebra in diseases classified elsewhere	0.065	0.935
M86.6 Other chronic osteomyelitis	0.064	0.936
M70-M79 Other soft tissue disorders	0.064	0.936
M49.8 Spondylopathy in other diseases classified elsewhere	0.064	0.936
M49.4 Neuropathic spondylopathy	0.064	0.936
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.064	0.936
M49.2 Enterobacterial spondylitis	0.064	0.936
M49.1 Brucella spondylitis	0.064	0.936
M49.0 Tuberculosis of spine	0.064	0.936
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.064	0.936
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.064	0.936
M96.5 Postradiation scoliosis	0.064	0.936
M96.4 Postsurgical lordosis	0.064	0.936
M96.3 Postlaminectomy kyphosis	0.064	0.936
M96.2 Postradiation kyphosis	0.064	0.936
M24.1 Other articular cartilage disorders	0.063	0.937
M24.23 Disorder of ligament (Forearm)	0.063	0.937
M08.9 Juvenile arthritis, unspecified	0.062	0.938
M08.8 Other juvenile arthritis	0.062	0.938
M08.4 Pauciarticular juvenile arthritis	0.062	0.938
M08.3 Juvenile polyarthritis (seronegative)	0.062	0.938
M08.2 Juvenile arthritis with systemic onset	0.062	0.938
M08.1 Juvenile ankylosing spondylitis	0.062	0.938
M08.0 Juvenile rheumatoid arthritis	0.062	0.938
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.062	0.938
M09.2 Juvenile arthritis in ulcerative colitis	0.062	0.938
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.062	0.938
M09.0 Juvenile arthritis in psoriasis	0.062	0.938
M12.8 Other specific arthropathies, not elsewhere classified	0.062	0.938
M12.5 Traumatic arthropathy	0.062	0.938
M12.4 Intermittent hydrarthrosis	0.062	0.938
M12.3 Palindromic rheumatism	0.062	0.938
M12.2 Villonodular synovitis (pigmented)	0.062	0.938
M12.1 Kaschin-Beck disease	0.062	0.938
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.062	0.938
M14.8 Arthropathies in other specified diseases classified elsewhere	0.062	0.938
M14.6 Neuropathic arthropathy	0.062	0.938
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.062	0.938
M14.4 Arthropathy in amyloidosis	0.062	0.938
M14.3 Lipoid dermatoarthritis	0.062	0.938
M14.2 Diabetic arthropathy	0.062	0.938
M14.1 Crystal arthropathy in other metabolic disorders	0.062	0.938
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.062	0.938
M10 Gout	0.062	0.938
M80.0 Postmenopausal osteoporosis with pathological fracture	0.062	0.938
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.062	0.938
M17.9 Gonarthrosis, unspecified	0.062	0.938
M83.9 Adult osteomalacia, unspecified	0.062	0.938
M83.8 Other adult osteomalacia	0.062	0.938
M83.5 Other drug-induced osteomalacia in adults	0.062	0.938
M83.4 Aluminum bone disease	0.062	0.938
M83.3 Adult osteomalacia due to malnutrition	0.062	0.938
M83.2 Adult osteomalacia due to malabsorption	0.062	0.938
M83.1 Senile osteomalacia	0.062	0.938
M83.0 Puerperal osteomalacia	0.062	0.938
M82.8 Osteoporosis in other diseases classified elsewhere	0.061	0.939
M82.0 Osteoporosis in multiple myelomatosis	0.061	0.939
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.061	0.939
M92.6 Juvenile osteochondrosis of tarsus	0.061	0.939
M89.89 Other specified disorders of bone (Site unspecified)	0.061	0.939
M89.88 Other specified disorders of bone (Other)	0.061	0.939
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.061	0.939
M89.84 Other specified disorders of bone (Hand)	0.061	0.939
M89.83 Other specified disorders of bone (Forearm)	0.061	0.939
M89.82 Other specified disorders of bone (Upper arm)	0.061	0.939
M89.80 Other specified disorders of bone (Multiple sites)	0.061	0.939
M23.1 Discoid meniscus (congenital)	0.061	0.939
M65.3 Trigger finger	0.061	0.939
M92.5 Juvenile osteochondrosis of tibia and fibula	0.061	0.939
M92.1 Juvenile osteochondrosis of radius and ulna	0.061	0.939
M92.9 Juvenile osteochondrosis, unspecified	0.061	0.939
M92.8 Other specified juvenile osteochondrosis	0.061	0.939
M92.7 Juvenile osteochondrosis of metatarsus	0.061	0.939
M92.4 Juvenile osteochondrosis of patella	0.061	0.939
M92.3 Other juvenile osteochondrosis of upper limb	0.061	0.939
M92.2 Juvenile osteochondrosis of hand	0.061	0.939
M92.0 Juvenile osteochondrosis of humerus	0.061	0.939
M21.29 Flexion deformity (Site unspecified)	0.061	0.939
M21.28 Flexion deformity (Other)	0.061	0.939
M21.27 Flexion deformity (Ankle and foot)	0.061	0.939
M21.26 Flexion deformity (Lower leg)	0.061	0.939
M21.25 Flexion deformity (Pelvic region and thigh)	0.061	0.939
M21.23 Flexion deformity (Forearm)	0.061	0.939
M21.22 Flexion deformity (Upper arm)	0.061	0.939
M21.21 Flexion deformity (Shoulder region)	0.061	0.939
M21.20 Flexion deformity (Multiple sites)	0.061	0.939
M85.88 Other specified disorders of bone density and structure (Other)	0.061	0.939
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.061	0.939
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.061	0.939
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.061	0.939
M85.84 Other specified disorders of bone density and structure (Hand)	0.061	0.939
M85.83 Other specified disorders of bone density and structure (Forearm)	0.061	0.939
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.061	0.939
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.061	0.939
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.061	0.939
M00.9 Pyogenic arthritis, unspecified	0.060	0.939
M91.9 Juvenile osteochondrosis of hip and pelvis, unspecified	0.060	0.939
M91.8 Other juvenile osteochondrosis of hip and pelvis	0.060	0.939
M91.3 Pseudocoxalgia	0.060	0.939
M91.2 Coxa plana	0.060	0.939
M91.1 Juvenile osteochondrosis of head of femur [Legg-Calve-Perthes]	0.060	0.939
M91.0 Juvenile osteochondrosis of pelvis	0.060	0.939
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.060	0.939
M82.1 Osteoporosis in endocrine disorders	0.060	0.939
M47.96 Spondylosis, unspecified (Lumbar region)	0.060	0.940
M50.3 Other cervical disk degeneration	0.060	0.940
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.060	0.940
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.060	0.940
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.060	0.940
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.060	0.940
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.060	0.940
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.060	0.940
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.060	0.940
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.060	0.940
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.060	0.940
M65.2 Calcific tendinitis	0.060	0.940
M65.1 Other infective (teno)synovitis	0.060	0.940
M65.0 Abscess of tendon sheath	0.060	0.940
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.060	0.940
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.060	0.940
M47.1 Other spondylosis with myelopathy	0.060	0.940
M23.9 Internal derangement of knee, unspecified	0.059	0.941
M95.0 Acquired deformity of nose	0.059	0.941
M11.09 Hydroxyapatite deposition disease (Site unspecified)	0.059	0.941
M11.08 Hydroxyapatite deposition disease (Other)	0.059	0.941
M11.07 Hydroxyapatite deposition disease (Ankle and foot)	0.059	0.941
M11.06 Hydroxyapatite deposition disease (Lower leg)	0.059	0.941
M11.05 Hydroxyapatite deposition disease (Pelvic region and thigh)	0.059	0.941
M11.04 Hydroxyapatite deposition disease (Hand)	0.059	0.941
M11.03 Hydroxyapatite deposition disease (Forearm)	0.059	0.941
M11.02 Hydroxyapatite deposition disease (Upper arm)	0.059	0.941
M11.01 Hydroxyapatite deposition disease (Shoulder region)	0.059	0.941
M11.00 Hydroxyapatite deposition disease (Multiple sites)	0.059	0.941
M11.19 Familial chondrocalcinosis (Site unspecified)	0.059	0.941
M11.18 Familial chondrocalcinosis (Other)	0.059	0.941
M11.17 Familial chondrocalcinosis (Ankle and foot)	0.059	0.941
M11.16 Familial chondrocalcinosis (Lower leg)	0.059	0.941
M11.15 Familial chondrocalcinosis (Pelvic region and thigh)	0.059	0.941
M11.14 Familial chondrocalcinosis (Hand)	0.059	0.941
M11.13 Familial chondrocalcinosis (Forearm)	0.059	0.941
M11.12 Familial chondrocalcinosis (Upper arm)	0.059	0.941
M11.11 Familial chondrocalcinosis (Shoulder region)	0.059	0.941
M11.10 Familial chondrocalcinosis (Multiple sites)	0.059	0.941
M11.89 Other specified crystal arthropathies (Site unspecified)	0.059	0.941
M11.88 Other specified crystal arthropathies (Other)	0.059	0.941
M11.87 Other specified crystal arthropathies (Ankle and foot)	0.059	0.941
M11.86 Other specified crystal arthropathies (Lower leg)	0.059	0.941
M11.85 Other specified crystal arthropathies (Pelvic region and thigh)	0.059	0.941
M11.84 Other specified crystal arthropathies (Hand)	0.059	0.941
M11.83 Other specified crystal arthropathies (Forearm)	0.059	0.941
M11.82 Other specified crystal arthropathies (Upper arm)	0.059	0.941
M11.81 Other specified crystal arthropathies (Shoulder region)	0.059	0.941
M11.80 Other specified crystal arthropathies (Multiple sites)	0.059	0.941
M11.99 Crystal arthropathy, unspecified (Site unspecified)	0.059	0.941
M11.98 Crystal arthropathy, unspecified (Other)	0.059	0.941
M11.97 Crystal arthropathy, unspecified (Ankle and foot)	0.059	0.941
M11.96 Crystal arthropathy, unspecified (Lower leg)	0.059	0.941
M11.95 Crystal arthropathy, unspecified (Pelvic region and thigh)	0.059	0.941
M11.94 Crystal arthropathy, unspecified (Hand)	0.059	0.941
M11.93 Crystal arthropathy, unspecified (Forearm)	0.059	0.941
M11.92 Crystal arthropathy, unspecified (Upper arm)	0.059	0.941
M11.91 Crystal arthropathy, unspecified (Shoulder region)	0.059	0.941
M11.90 Crystal arthropathy, unspecified (Multiple sites)	0.059	0.941
M24.09 Loose body in joint (Site unspecified)	0.059	0.941
M24.08 Loose body in joint (Other)	0.059	0.941
M24.07 Loose body in joint (Ankle and foot)	0.059	0.941
M24.06 Loose body in joint-Lower leg	0.059	0.941
M24.05 Loose body in joint (Pelvic region and thigh)	0.059	0.941
M24.04 Loose body in joint (Hand)	0.059	0.941
M24.03 Loose body in joint (Forearm)	0.059	0.941
M24.02 Loose body in joint (Upper arm)	0.059	0.941
M24.00 Loose body in joint (Multiple sites)	0.059	0.941
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.059	0.941
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.059	0.941
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.059	0.941
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.059	0.941
M54.92 Dorsalgia, unspecified (Cervical region)	0.059	0.941
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.059	0.941
M23.8 Other internal derangements of knee	0.059	0.941
M21.39 Wrist or foot drop (acquired)-Site unspec	0.059	0.941
M21.38 Wrist or foot drop (acquired)-Other	0.059	0.941
M21.36 Wrist or foot drop (acquired)-Lower leg	0.059	0.941
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.059	0.941
M21.34 Wrist or foot drop (acquired) (Hand)	0.059	0.941
M21.33 Wrist or foot drop (acquired) (Forearm)	0.059	0.941
M21.32 Wrist or foot drop (acquired)-Upper arm	0.059	0.941
M21.31 Wrist or foot drop (acquired)-Shldr region	0.059	0.941
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.059	0.941
M86.8 Other osteomyelitis	0.059	0.941
M86.5 Other chronic haematogenous osteomyelitis	0.059	0.941
M86.4 Chronic osteomyelitis with draining sinus	0.059	0.941
M86.3 Chronic multifocal osteomyelitis	0.059	0.941
M86.2 Subacute osteomyelitis	0.059	0.941
M86.1 Other acute osteomyelitis	0.059	0.941
M86.0 Acute haematogenous osteomyelitis	0.059	0.941
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.058	0.941
M19 Other arthrosis	0.059	0.941
M23.0 Cystic meniscus	0.058	0.942
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.058	0.942
M65.4 Radial styloid tenosynovitis [de Quervain]	0.058	0.942
M54.64 Pain in thoracic spine (Thoracic region)	0.058	0.942
M94.89 Other specified disorders of cartilage (Site unspecified)	0.057	0.942

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations