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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12206077
log Bayes Factor = 41.6054
Chromosome 6   position 29,440,741  (GRCh37) Explore rs12206077 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.002 0.998
E10.3 With ophthalmic complications
0.000 0.014 0.986
E10-E14 Diabetes mellitus
0.000 0.019 0.981
E10.1 With ketoacidosis
0.000 0.031 0.969
E13 Other specified diabetes mellitus
0.000 0.046 0.954
E10.2 With renal complications
0.000 0.055 0.945
E13.9 Without complications
0.000 0.066 0.934
E10.4 With neurological complications
0.000 0.096 0.904
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.128 0.872
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.150 0.850
E16 Other disorders of pancreatic internal secretion
0.000 0.166 0.834
E10.6 With other specified complications
0.000 0.169 0.831
E16.2 Hypoglycaemia, unspecified
0.000 0.184 0.816
E00-E07 Disorders of thyroid gland
0.000 0.186 0.814
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.189 0.811
E05.9 Thyrotoxicosis, unspecified
0.000 0.199 0.801
E14 Unspecified diabetes mellitus
0.000 0.210 0.790
E20-E35 Disorders of other endocrine glands
0.000 0.226 0.774
E10.0 With coma
0.000 0.227 0.773
E10.5 With peripheral circulatory complications
0.000 0.239 0.761
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.269 0.731
E23 Hypofunction and other disorders of pituitary gland
0.000 0.270 0.730
E10.7 With multiple complications
0.000 0.283 0.717
E16.1 Other hypoglycaemia
0.000 0.288 0.712
E12 Malnutrition-related diabetes mellitus
0.000 0.296 0.703
E05.8 Other thyrotoxicosis
0.000 0.301 0.699
E23.0 Hypopituitarism
0.000 0.314 0.686
E13.8 With unspecified complications
0.000 0.316 0.684
E13.7 With multiple complications
0.000 0.316 0.684
E13.6 With other specified complications
0.000 0.316 0.684
E13.5 With peripheral circulatory complications
0.000 0.316 0.684
E13.4 With neurological complications
0.000 0.316 0.684
E13.3 With ophthalmic complications
0.000 0.316 0.684
E13.2 With renal complications
0.000 0.316 0.684
E13.1 With ketoacidosis
0.000 0.316 0.684
E13.0 With coma
0.000 0.316 0.684
E24 Cushing's syndrome
0.000 0.322 0.678
E10.8 With unspecified complications
0.000 0.352 0.648
E22 Hyperfunction of pituitary gland
0.000 0.363 0.637
E14.6 With other specified complications
0.000 0.373 0.627
E23.2 Diabetes insipidus
0.000 0.376 0.624
E20 Hypoparathyroidism
0.000 0.382 0.618
E15 Nondiabetic hypoglycaemic coma
0.000 0.391 0.609
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.398 0.602
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.402 0.598
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.402 0.598
E16.4 Abnormal secretion of gastrin
0.000 0.402 0.598
E16.3 Increased secretion of glucagon
0.000 0.402 0.598
E14.2 Withrenal complications
0.000 0.404 0.596
E50-E64 Other nutritional deficiencies
0.000 0.410 0.590
E14.9 Without complications
0.000 0.410 0.590
E14.4 With neurological complications
0.000 0.412 0.587
E14.1 With ketoacidosis
0.000 0.415 0.585
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.416 0.584
E00 Congenital iodine-deficiency syndrome
0.000 0.416 0.584
E24.9 Cushing's syndrome, unspecified
0.000 0.416 0.584
E05.5 Thyroid crisis or storm
0.000 0.419 0.581
E05.4 Thyrotoxicosis factitia
0.000 0.419 0.581
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.419 0.581
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.419 0.581
E29 Testicular dysfunction
0.000 0.420 0.580
E40-E46 Malnutrition
0.000 0.424 0.576
E14.8 With unspecified complications
0.000 0.427 0.573
E14.7 With multiple complications
0.000 0.434 0.566
E14.5 With peripheral circulatory complications
0.000 0.434 0.566
E14.0 With coma
0.000 0.434 0.566
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.436 0.564
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.445 0.555
E32 Diseases of thymus
0.000 0.445 0.555
E30 Disorders of puberty, not elsewhere classified
0.000 0.445 0.555
E25 Adrenogenital disorders
0.000 0.445 0.555
E07 Other disorders of thyroid
0.000 0.454 0.546
E23.7 Disorder of pituitary gland, unspecified
0.000 0.455 0.545
E24.2 Drug-induced Cushing's syndrome
0.000 0.461 0.538
E28 Ovarian dysfunction
0.000 0.471 0.528
E22.0 Acromegaly and pituitary gigantism
0.000 0.475 0.525
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.477 0.523
E23.1 Drug-induced hypopituitarism
0.000 0.477 0.523
E20.9 Hypoparathyroidism, unspecified
0.000 0.494 0.506
E12.9 Without complications
0.000 0.495 0.504
E12.8 With unspecified complications
0.000 0.495 0.504
E12.7 With multiple complications
0.000 0.495 0.504
E12.6 With other specified complications
0.000 0.495 0.504
E12.5 With peripheral circulatory complications
0.000 0.495 0.504
E12.4 With neurological complications
0.000 0.495 0.504
E12.3 With ophthalmic complications
0.000 0.495 0.504
E12.2 With renal complications
0.000 0.495 0.504
E12.1 With ketoacidosis
0.000 0.495 0.504
E12.0 With coma
0.000 0.495 0.504
E31 Polyglandular dysfunction
0.000 0.502 0.498
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.510 0.490
E14.3 With ophthalmic complications
0.000 0.513 0.487
E24.8 Other Cushing's syndrome
0.000 0.514 0.486
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.514 0.486
E24.3 Ectopic ACTH syndrome
0.000 0.514 0.486
E24.1 Nelson's syndrome
0.000 0.514 0.486
E24.0 Pituitary-dependent Cushing's disease
0.000 0.514 0.486
E11 Non-insulin-dependent diabetes mellitus
0.000 0.516 0.484
E55 Vitamin D deficiency
0.000 0.536 0.464
E06 Thyroiditis
0.000 0.537 0.463
E27 Other disorders of adrenal gland
0.000 0.539 0.461
E26 Hyperaldosteronism
0.000 0.540 0.460
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.543 0.457
E22.8 Other hyperfunction of pituitary gland
0.000 0.543 0.457
E34 Other endocrine disorders
0.000 0.555 0.444
E22.1 Hyperprolactinaemia
0.000 0.556 0.444
E20.8 Other hypoparathyroidism
0.000 0.557 0.443
E20.1 Pseudohypoparathyroidism
0.000 0.557 0.443
E20.0 Idiopathic hypoparathyroidism
0.000 0.557 0.443
E29.1 Testicular hypofunction
0.000 0.559 0.440
E11.2 With renal complications
0.000 0.572 0.428
E11.6 With other specified complications
0.000 0.576 0.424
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.577 0.423
E63 Other nutritional deficiencies
0.000 0.577 0.423
E56 Other vitamin deficiencies
0.000 0.577 0.423
E51 Thiamine deficiency
0.000 0.577 0.423
E50 Vitamin A deficiency
0.000 0.577 0.423
E60 Dietary zinc deficiency
0.000 0.577 0.423
E59 Dietary selenium deficiency
0.000 0.577 0.423
E54 Ascorbic acid deficiency
0.000 0.577 0.423
E52 Niacin deficiency [pellagra]
0.000 0.577 0.423
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.581 0.419
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.581 0.419
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.581 0.419
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.581 0.419
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.581 0.419
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.581 0.419
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.581 0.419
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.581 0.419
E29.9 Testicular dysfunction, unspecified
0.000 0.584 0.416
E29.8 Other testicular dysfunction
0.000 0.584 0.416
E29.0 Testicular hyperfunction
0.000 0.584 0.416
E53 Deficiency of other B group vitamins
0.000 0.586 0.414
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.587 0.413
E45 Retarded development following protein-energy malnutrition
0.000 0.587 0.413
E43 Unspecified severe protein-energy malnutrition
0.000 0.587 0.413
E42 Marasmic kwashiorkor
0.000 0.587 0.413
E41 Nutritional marasmus
0.000 0.587 0.413
E40 Kwashiorkor
0.000 0.587 0.413
E23.6 Other disorders of pituitary gland
0.000 0.595 0.405
E07.8 Other specified disorders of thyroid
0.000 0.598 0.402
E25.9 Adrenogenital disorder, unspecified
0.000 0.602 0.398
E25.8 Other adrenogenital disorders
0.000 0.602 0.398
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.602 0.398
E30.9 Disorder of puberty, unspecified
0.000 0.602 0.398
E30.8 Other disorders of puberty
0.000 0.602 0.398
E30.1 Precocious puberty
0.000 0.602 0.398
E30.0 Delayed puberty
0.000 0.602 0.398
E32.9 Disease of thymus, unspecified
0.000 0.602 0.398
E32.8 Other diseases of thymus
0.000 0.602 0.398
E32.1 Abscess of thymus
0.000 0.602 0.398
E32.0 Persistent hyperplasia of thymus
0.000 0.602 0.398
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.602 0.398
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.602 0.398
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.602 0.398
E28.3 Primary ovarian failure
0.000 0.604 0.396
E07.1 Dyshormogenetic goitre
0.000 0.608 0.391
E07.0 Hypersecretion of calcitonin
0.000 0.608 0.391
E11.0 With coma
0.000 0.609 0.391
E03 Other hypothyroidism
0.000 0.610 0.389
E27.1 Primary adrenocortical insufficiency
0.000 0.613 0.387
E61 Deficiency of other nutrient elements
0.000 0.613 0.387
E58 Dietary calcium deficiency
0.000 0.617 0.382
E28.9 Ovarian dysfunction, unspecified
0.000 0.621 0.379
E28.8 Other ovarian dysfunction
0.000 0.621 0.379
E28.1 Androgen excess
0.000 0.621 0.379
E28.0 Oestrogen excess
0.000 0.621 0.379
E55.9 Vitamin D deficiency, unspecified
0.000 0.627 0.373
E06.9 Thyroiditis, unspecified
0.000 0.633 0.367
K90 Intestinal malabsorption
0.000 0.635 0.365
E46 Unspecified protein-energy malnutrition
0.000 0.635 0.365
E53.9 Vitamin B deficiency, unspecified
0.000 0.635 0.365
E31.9 Polyglandular dysfunction, unspecified
0.000 0.643 0.357
E31.8 Other polyglandular dysfunction
0.000 0.643 0.357
E31.1 Polyglandular hyperfunction
0.000 0.643 0.357
E11.1 With ketoacidosis
0.000 0.644 0.356
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.647 0.352
E11.7 With multiple complications
0.000 0.653 0.347
E11.8 With unspecified complications
0.000 0.656 0.344
E07.9 Disorder of thyroid, unspecified
0.000 0.661 0.339
E55.0 Rickets, active
0.000 0.667 0.333
E06.4 Drug-induced thyroiditis
0.000 0.668 0.332
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.668 0.332
E06.1 Subacute thyroiditis
0.000 0.668 0.332
E06.0 Acute thyroiditis
0.000 0.668 0.332
E27.5 Adrenomedullary hyperfunction
0.000 0.669 0.331
E27.0 Other adrenocortical overactivity
0.000 0.669 0.331
E26.9 Hyperaldosteronism, unspecified
0.000 0.670 0.330
E26.8 Other hyperaldosteronism
0.000 0.670 0.330
E26.1 Secondary hyperaldosteronism
0.000 0.670 0.330
E28.2 Polycystic ovarian syndrome
0.000 0.670 0.330
E27.8 Other specified disorders of adrenal gland
0.000 0.674 0.326
E34.8 Other specified endocrine disorders
0.000 0.675 0.325
E34.5 Androgen resistance syndrome
0.000 0.681 0.319
E34.4 Constitutional tall stature
0.000 0.681 0.319
E34.3 Short stature, not elsewhere classified
0.000 0.681 0.319
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.681 0.319
E34.1 Other hypersecretion of intestinal hormones
0.000 0.681 0.319
E03.8 Other specified hypothyroidism
0.000 0.682 0.318
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.685 0.315
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.686 0.314
E65-E68 Obesity and other hyperalimentation
0.000 0.691 0.309
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.693 0.307
E50.9 Vitamin A deficiency, unspecified
0.000 0.696 0.303
E50.8 Other manifestations of vitamin A deficiency
0.000 0.696 0.303
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.696 0.303
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.696 0.303
E50.5 Vitamin A deficiency with night blindness
0.000 0.696 0.303
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.696 0.303
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.696 0.303
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.696 0.303
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.696 0.303
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.696 0.303
E51.9 Thiamine deficiency, unspecified
0.000 0.696 0.303
E51.8 Other manifestations of thiamine deficiency
0.000 0.696 0.303
E51.2 Wernicke's encephalopathy
0.000 0.696 0.303
E51.1 Beriberi
0.000 0.696 0.303
E56.9 Vitamin deficiency, unspecified
0.000 0.696 0.303
E56.8 Deficiency of other vitamins
0.000 0.696 0.303
E56.1 Deficiency of vitamin K
0.000 0.696 0.303
E56.0 Deficiency of vitamin E
0.000 0.696 0.303
E63.9 Nutritional deficiency, unspecified
0.000 0.696 0.303
E63.8 Other specified nutritional deficiencies
0.000 0.696 0.303
E63.1 Imbalance of constituents of food intake
0.000 0.696 0.303
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.696 0.303
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.696 0.303
E64.8 Sequelae of other nutritional deficiencies
0.000 0.696 0.303
E64.3 Sequelae of rickets
0.000 0.696 0.303
E64.2 Sequelae of vitamin C deficiency
0.000 0.696 0.303
E64.1 Sequelae of vitamin A deficiency
0.000 0.696 0.303
E64.0 Sequelae of protein-energy malnutrition
0.000 0.696 0.303
E31.0 Autoimmune polyglandular failure
0.000 0.699 0.300
E53.1 Pyridoxine deficiency
0.000 0.703 0.297
E53.0 Riboflavin deficiency
0.000 0.703 0.297
E44.1 Mild protein-energy malnutrition
0.000 0.703 0.296
E44.0 Moderate protein-energy malnutrition
0.000 0.703 0.296
E27.9 Disorder of adrenal gland, unspecified
0.000 0.709 0.291
E34.9 Endocrine disorder, unspecified
0.000 0.713 0.286
E06.5 Other chronic thyroiditis
0.000 0.714 0.286
E03.5 Myxoedema coma
0.000 0.721 0.279
E03.4 Atrophy of thyroid (acquired)
0.000 0.721 0.279
E03.3 Postinfectious hypothyroidism
0.000 0.721 0.279
E03.1 Congenital hypothyroidism without goitre
0.000 0.721 0.279
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.721 0.279
E61.9 Deficiency of nutrient element, unspecified
0.000 0.722 0.277
E61.8 Deficiency of other specified nutrient elements
0.000 0.722 0.277
E61.7 Deficiency of multiple nutrient elements
0.000 0.722 0.277
E61.6 Vanadium deficiency
0.000 0.722 0.277
E61.5 Molybdenum deficiency
0.000 0.722 0.277
E61.4 Chromium deficiency
0.000 0.722 0.277
E61.3 Manganese deficiency
0.000 0.722 0.277
E61.0 Copper deficiency
0.000 0.722 0.277
E61.1 Iron deficiency
0.000 0.727 0.273
E83 Disorders of mineral metabolism
0.272 0.728 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.732 0.268
K90.3 Pancreatic steatorrhoea
0.000 0.738 0.262
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.738 0.262
K90.1 Tropical sprue
0.000 0.738 0.262
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.743 0.257
K90.8 Other intestinal malabsorption
0.000 0.750 0.250
E34.0 Carcinoid syndrome
0.000 0.753 0.247
E61.2 Magnesium deficiency
0.000 0.753 0.247
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.756 0.244
E27.2 Addisonian crisis
0.000 0.756 0.244
E11.5 With peripheral circulatory complications
0.000 0.763 0.237
E26.0 Primary hyperaldosteronism
0.000 0.765 0.234
K90.9 Intestinal malabsorption, unspecified
0.000 0.766 0.234
E21.4 Other specified disorders of parathyroid gland
0.000 0.775 0.225
E21.2 Other hyperparathyroidism
0.000 0.775 0.225
E83.3 Disorders of phosphorus metabolism
0.225 0.775 0.000
E11.4 With neurological complications
0.000 0.776 0.224
E67 Other hyperalimentation
0.000 0.778 0.222
E68 Sequelae of hyperalimentation
0.000 0.778 0.222
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.213 0.787 0.000
E06.3 Autoimmune thyroiditis
0.000 0.789 0.210
E04 Other non-toxic goitre
0.000 0.791 0.208
E21.3 Hyperparathyroidism, unspecified
0.000 0.799 0.201
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.801 0.199
E83.9 Disorder of mineral metabolism, unspecified
0.195 0.805 0.000
E83.8 Other disorders of mineral metabolism
0.195 0.805 0.000
E83.2 Disorders of zinc metabolism
0.195 0.805 0.000
E83.0 Disorders of copper metabolism
0.195 0.805 0.000
E04.9 Non-toxic goitre, unspecified
0.000 0.817 0.183
E65 Localised adiposity
0.000 0.817 0.183
E83.4 Disorders of magnesium metabolism
0.171 0.829 0.000
E67.8 Other specified hyperalimentation
0.000 0.841 0.159
E67.3 Hypervitaminosis D
0.000 0.841 0.159
E67.2 Megavitamin-B6 syndrome
0.000 0.841 0.159
E67.1 Hypercarotenaemia
0.000 0.841 0.159
E67.0 Hypervitaminosis A
0.000 0.841 0.159
E11.9 Without complications
0.000 0.844 0.156
E04.8 Other specified non-toxic goitre
0.000 0.850 0.149
I83 Varicose veins of lower extremities
0.121 0.879 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.884 0.116
K51 Ulcerative colitis
0.115 0.885 0.000
K51.9 Ulcerative colitis, unspecified
0.109 0.891 0.000
E11.3 With ophthalmic complications
0.000 0.891 0.109
K51.4 Pseudopolyposis of colon
0.109 0.891 0.000
E04.0 Non-toxic diffuse goitre
0.001 0.892 0.108
K51.3 Ulcerative (chronic) rectosigmoiditis
0.106 0.894 0.000
K51.2 Ulcerative (chronic) proctitis
0.105 0.895 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.102 0.898 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.100 0.900 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.094 0.906 0.000
K51.5 Mucosal proctocolitis
0.086 0.914 0.000
E83.5 Disorders of calcium metabolism
0.084 0.916 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.084 0.916 0.000
K51.8 Other ulcerative colitis
0.080 0.920 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.077 0.923 0.000
E21.0 Primary hyperparathyroidism
0.000 0.939 0.060
K50-K52 Noninfective enteritis and colitis
0.041 0.959 0.000
K50 Crohn's disease [regional enteritis]
0.037 0.963 0.000
K50.9 Crohn's disease, unspecified
0.033 0.967 0.000
E66 Obesity
0.000 0.970 0.030
K50.0 Crohn's disease of small intestine
0.029 0.971 0.000
E04.1 Non-toxic single thyroid nodule
0.001 0.973 0.026
K50.1 Crohn's disease of large intestine
0.027 0.973 0.000
K50.8 Other Crohn's disease
0.023 0.976 0.000
E66.1 Drug-induced obesity
0.000 0.978 0.022
K90-K93 Other diseases of the digestive system
0.000 0.979 0.021
E66.0 Obesity due to excess calories
0.000 0.982 0.018
E04.2 Non-toxic multinodular goitre
0.001 0.982 0.017
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.984 0.015
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.985 0.015
F45.8 Other somatoform disorders
0.000 0.986 0.014
H54.0 Blindness, both eyes
0.000 0.987 0.013
C43.5 Malignant melanoma of trunk
0.000 0.988 0.012
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.989 0.011
K93.1 Megacolon in Chagas' disease
0.000 0.989 0.011
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.989 0.011
J35.8 Other chronic diseases of tonsils and adenoids
0.011 0.989 0.000
H54 Blindness and low vision
0.000 0.989 0.011
H54.9 Unspecified visual impairment (binocular)
0.000 0.989 0.011
E70-E90 Metabolic disorders
0.003 0.989 0.007
V18.0 Driver injured in nontraffic accident
0.010 0.990 0.000
J38.4 Oedema of larynx
0.010 0.990 0.000
J38.7 Other diseases of larynx
0.010 0.990 0.000
H54.6 Unqualified visual loss, one eye
0.000 0.991 0.009
H54.5 Low vision, one eye
0.000 0.991 0.009
H54.7 Unspecified visual loss
0.000 0.991 0.009
F45 Somatoform disorders
0.000 0.991 0.009
E73 Lactose intolerance
0.002 0.992 0.007
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.008 0.992 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.008 0.992 0.000
H54.2 Low vision, both eyes
0.000 0.992 0.008
H54.3 Unqualified visual loss, both eyes
0.000 0.992 0.008
E79 Disorders of purine and pyrimidine metabolism
0.002 0.992 0.006
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.002 0.992 0.006
E74 Other disorders of carbohydrate metabolism
0.002 0.992 0.006
E77 Disorders of glycoprotein metabolism
0.003 0.992 0.005
E76 Disorders of glycosaminoglycan metabolism
0.003 0.992 0.005
E72 Other disorders of amino-acid metabolism
0.003 0.992 0.005
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.003 0.992 0.005
E70 Disorders of aromatic amino-acid metabolism
0.003 0.992 0.005
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.003 0.992 0.005
E84 Cystic fibrosis
0.003 0.992 0.005
J38.3 Other diseases of vocal cords
0.007 0.993 0.000
A08.4 Viral intestinal infection, unspecified
0.000 0.993 0.007
J38.5 Laryngeal spasm
0.007 0.993 0.000
E85 Amyloidosis
0.002 0.993 0.005
F45.9 Somatoform disorder, unspecified
0.000 0.993 0.007
E66.8 Other obesity
0.000 0.993 0.007
H54.4 Blindness, one eye
0.000 0.993 0.007
E73.9 Lactose intolerance, unspecified
0.001 0.993 0.006
H54.1 Blindness, one eye, low vision, other eye
0.000 0.993 0.007
F45.0 Somatisation disorder
0.000 0.993 0.007
C50.3 Lower-inner quadrant of breast
0.000 0.993 0.007
S62.30 Fracture of other metacarpal bone (closed)
0.000 0.993 0.007
F45.3 Somatoform autonomic dysfunction
0.000 0.993 0.007
F45.2 Hypochondriacal disorder
0.000 0.993 0.007
J38.2 Nodules of vocal cords
0.007 0.993 0.000
F45.4 Persistent somatoform pain disorder
0.000 0.993 0.006
F45.1 Undifferentiated somatoform disorder
0.000 0.993 0.006
S42.10 Fracture of scapula (closed)
0.000 0.994 0.006
E73.8 Other lactose intolerance
0.001 0.994 0.005
E73.1 Secondary lactase deficiency
0.001 0.994 0.005
E73.0 Congenital lactase deficiency
0.001 0.994 0.005
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.994 0.005
C50.8 Overlapping lesion of breast
0.000 0.994 0.006
J35.2 Hypertrophy of adenoids
0.006 0.994 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.994 0.006
E75.5 Other lipid storage disorders
0.002 0.994 0.005
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.002 0.994 0.004
E79.8 Other disorders of purine and pyrimidine metabolism
0.002 0.994 0.004
E79.1 Lesch-Nyhan syndrome
0.002 0.994 0.004
D47.4 Osteomyelofibrosis
0.000 0.994 0.006
E75.6 Lipid storage disorder, unspecified
0.002 0.994 0.004
E75.4 Neuronal ceroid lipofuscinosis
0.002 0.994 0.004
E75.3 Sphingolipidosis, unspecified
0.002 0.994 0.004
E75.2 Other sphingolipidosis
0.002 0.994 0.004
E75.1 Other gangliosidosis
0.002 0.994 0.004
E75.0 GM2 gangliosidosis
0.002 0.994 0.004
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.994 0.005
E74.9 Disorder of carbohydrate metabolism, unspecified
0.002 0.994 0.004
E74.8 Other specified disorders of carbohydrate metabolism
0.002 0.994 0.004
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.002 0.994 0.004
E74.2 Disorders of galactose metabolism
0.002 0.994 0.004
E74.1 Disorders of fructose metabolism
0.002 0.994 0.004
E74.0 Glycogen storage disease
0.002 0.994 0.004
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.002 0.994 0.004
E70.8 Other disorders of aromatic amino-acid metabolism
0.002 0.994 0.004
E70.3 Albinism
0.002 0.994 0.004
E70.2 Disorders of tyrosine metabolism
0.002 0.994 0.004
E70.1 Other hyperphenylalaninaemias
0.002 0.994 0.004
E70.0 Classical phenylketonuria
0.002 0.994 0.004
E71.3 Disorders of fatty-acid metabolism
0.002 0.994 0.004
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.002 0.994 0.004
E71.1 Other disorders of branched-chain amino-acid metabolism
0.002 0.994 0.004
E71.0 Maple-syrup-urine disease
0.002 0.994 0.004
E72.9 Disorder of amino-acid metabolism, unspecified
0.002 0.994 0.004
E72.8 Other specified disorders of amino-acid metabolism
0.002 0.994 0.004
E72.5 Disorders of glycine metabolism
0.002 0.994 0.004
E72.4 Disorders of ornithine metabolism
0.002 0.994 0.004
E72.3 Disorders of lysine and hydroxylysine metabolism
0.002 0.994 0.004
E72.2 Disorders of urea cycle metabolism
0.002 0.994 0.004
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.002 0.994 0.004
E72.0 Disorders of amino-acid transport
0.002 0.994 0.004
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.002 0.994 0.004
E76.8 Other disorders of glucosaminoglycan metabolism
0.002 0.994 0.004
E76.3 Mucopolysaccharidosis, unspecified
0.002 0.994 0.004
E76.2 Other mucopolysaccharidoses
0.002 0.994 0.004
E76.1 Mucopolysaccharidosis, type II
0.002 0.994 0.004
E76.0 Mucopolysaccharidosis, type I
0.002 0.994 0.004
E77.9 Disorder of glycoprotein metabolism, unspecified
0.002 0.994 0.004
E77.8 Other disorders of glycoprotein metabolism
0.002 0.994 0.004
E77.1 Defects in glycoprotein degradation
0.002 0.994 0.004
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.002 0.994 0.004
K04.5 Chronic apical periodontitis
0.006 0.994 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.006 0.994 0.000
E84.8 Cystic fibrosis with other manifestations
0.002 0.994 0.004
E84.1 Cystic fibrosis with intestinal manifestations
0.002 0.994 0.004
E84.0 Cystic fibrosis with pulmonary manifestations
0.002 0.994 0.004
E88 Other metabolic disorders
0.002 0.994 0.004
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.994 0.006
J35 Chronic diseases of tonsils and adenoids
0.006 0.994 0.000
E84.9 Cystic fibrosis, unspecified
0.002 0.994 0.004
C50 Malignant neoplasm of breast
0.000 0.994 0.006
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.994 0.006
J38.6 Stenosis of larynx
0.005 0.994 0.000
D47.2 Monoclonal gammopathy
0.000 0.995 0.005
E85.8 Other amyloidosis
0.002 0.995 0.004
E85.2 Heredofamilial amyloidosis, unspecified
0.002 0.995 0.004
E85.1 Neuropathic heredofamilial amyloidosis
0.002 0.995 0.004
E85.0 Nonneuropathic heredofamilial amyloidosis
0.002 0.995 0.004
E85.4 Organ-limited amyloidosis
0.001 0.995 0.004
J38.1 Polyp of vocal cord and larynx
0.005 0.995 0.000
E85.3 Secondary systemic amyloidosis
0.001 0.995 0.004
E80 Disorders of porphyrin and bilirubin metabolism
0.003 0.995 0.003
T85.4 Mechanical complication of breast prosthesis and implant
0.000 0.995 0.005
C50.4 Upper-outer quadrant of breast
0.000 0.995 0.005
E85.9 Amyloidosis, unspecified
0.002 0.995 0.003
C50.1 Central portion of breast
0.000 0.995 0.005
V18.5 Passenger injured in traffic accident
0.005 0.995 0.000
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.995 0.005
V18.1 Passenger injured in nontraffic accident
0.004 0.995 0.000
V18.9 Unspecified pedal cyclist injured in traffic accident
0.004 0.995 0.000
V18.4 Driver injured in traffic accident
0.004 0.995 0.000
E88.9 Metabolic disorder, unspecified
0.002 0.996 0.003
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.996 0.003
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids
0.004 0.996 0.000
E88.2 Lipomatosis, not elsewhere classified
0.001 0.996 0.003
C50.6 Axillary tail of breast
0.000 0.996 0.004
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.996 0.004
E88.3 Tumour lysis syndrome
0.002 0.996 0.003
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.996 0.004
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.000 0.996 0.004
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.000 0.996 0.004
V18.3 Person injured while boarding or alighting
0.004 0.996 0.000
E88.8 Other specified metabolic disorders
0.002 0.996 0.002
V18.2 Unspecified pedal cyclist injured in nontraffic accident
0.004 0.996 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.002 0.996 0.002
E80.5 Crigler-Najjar syndrome
0.002 0.996 0.002
E80.3 Defects of catalase and peroxydase
0.002 0.996 0.002
E80.0 Hereditary erythropoietic porphyria
0.002 0.996 0.002
M79.09 Rheumatism, unspecified (Site unspecified)
0.000 0.996 0.004
E80.1 Porphyria cutanea tarda
0.002 0.996 0.002
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.996 0.004
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.996 0.004
E80.2 Other porphyria
0.002 0.996 0.002
S42.1 Fracture of scapula
0.000 0.996 0.004
E80.6 Other disorders of bilirubin metabolism
0.002 0.996 0.002
C50.0 Nipple and areola
0.000 0.996 0.004
J35.9 Chronic disease of tonsils and adenoids, unspecified
0.004 0.996 0.000
K52 Other non-infective gastro-enteritis and colitis
0.004 0.996 0.000
J35.0 Chronic tonsillitis
0.004 0.996 0.000
S62.3 Fracture of other metacarpal bone
0.000 0.996 0.004
C50.5 Lower-outer quadrant of breast
0.000 0.996 0.004
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.002 0.996 0.001
H40.2 Primary angle-closure glaucoma
0.004 0.996 0.000
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity
0.003 0.996 0.000
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity
0.003 0.996 0.000
S64.0 Injury of ulnar nerve at wrist and hand level
0.004 0.996 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.000 0.997 0.003
J38.0 Paralysis of vocal cords and larynx
0.003 0.997 0.000
N60.2 Fibroadenosis of breast
0.003 0.997 0.000
N18.4 Chronic kidney disease, stage 4
0.000 0.997 0.003
L43.9 Lichen planus, unspecified
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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