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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12211424
log Bayes Factor = 7.89599
Chromosome 6   position 27,435,024  (GRCh37) Explore rs12211424 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.000 0.140 0.860
E83 Disorders of mineral metabolism
0.000 0.641 0.359
E10.9 Without complications
0.000 0.671 0.329
E10 Insulin-dependent diabetes mellitus
0.000 0.681 0.319
E10.4 With neurological complications
0.000 0.695 0.305
K90 Intestinal malabsorption
0.000 0.714 0.286
E10.5 With peripheral circulatory complications
0.000 0.715 0.285
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.743 0.257
E83.8 Other disorders of mineral metabolism
0.000 0.743 0.257
E83.2 Disorders of zinc metabolism
0.000 0.743 0.257
E83.0 Disorders of copper metabolism
0.000 0.743 0.257
E10.6 With other specified complications
0.000 0.747 0.252
E83.4 Disorders of magnesium metabolism
0.000 0.750 0.250
E10.8 With unspecified complications
0.000 0.759 0.241
E10.3 With ophthalmic complications
0.000 0.767 0.233
E83.3 Disorders of phosphorus metabolism
0.000 0.769 0.231
E10.7 With multiple complications
0.000 0.771 0.229
E10-E14 Diabetes mellitus
0.000 0.771 0.229
E10.0 With coma
0.000 0.775 0.224
E83.5 Disorders of calcium metabolism
0.000 0.783 0.217
E10.2 With renal complications
0.000 0.794 0.206
K90.8 Other intestinal malabsorption
0.000 0.794 0.205
K90.3 Pancreatic steatorrhoea
0.000 0.794 0.205
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.794 0.205
K90.1 Tropical sprue
0.000 0.794 0.205
E13 Other specified diabetes mellitus
0.000 0.803 0.197
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.809 0.191
E10.1 With ketoacidosis
0.000 0.822 0.178
E13.9 Without complications
0.000 0.825 0.175
E70-E90 Metabolic disorders
0.000 0.833 0.167
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.834 0.166
E14 Unspecified diabetes mellitus
0.000 0.834 0.166
E12 Malnutrition-related diabetes mellitus
0.000 0.836 0.164
K90.9 Intestinal malabsorption, unspecified
0.000 0.845 0.155
E14.3 With ophthalmic complications
0.000 0.852 0.148
E88 Other metabolic disorders
0.000 0.854 0.146
E13.8 With unspecified complications
0.000 0.858 0.141
E13.7 With multiple complications
0.000 0.858 0.141
E13.6 With other specified complications
0.000 0.858 0.141
E13.5 With peripheral circulatory complications
0.000 0.858 0.141
E13.4 With neurological complications
0.000 0.858 0.141
E13.3 With ophthalmic complications
0.000 0.858 0.141
E13.2 With renal complications
0.000 0.858 0.141
E13.1 With ketoacidosis
0.000 0.858 0.141
E13.0 With coma
0.000 0.858 0.141
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.860 0.140
E85 Amyloidosis
0.000 0.863 0.137
E40-E46 Malnutrition
0.000 0.870 0.130
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.873 0.127
E14.4 With neurological complications
0.000 0.877 0.123
E16 Other disorders of pancreatic internal secretion
0.000 0.878 0.122
E84 Cystic fibrosis
0.000 0.880 0.120
E79 Disorders of purine and pyrimidine metabolism
0.000 0.880 0.120
E77 Disorders of glycoprotein metabolism
0.000 0.880 0.120
E76 Disorders of glycosaminoglycan metabolism
0.000 0.880 0.120
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.880 0.120
E72 Other disorders of amino-acid metabolism
0.000 0.880 0.120
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.880 0.120
E70 Disorders of aromatic amino-acid metabolism
0.000 0.880 0.120
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.880 0.120
E14.7 With multiple complications
0.000 0.881 0.119
E14.6 With other specified complications
0.000 0.881 0.119
E14.5 With peripheral circulatory complications
0.000 0.881 0.119
E14.2 Withrenal complications
0.000 0.881 0.119
E14.0 With coma
0.000 0.881 0.119
E12.9 Without complications
0.000 0.882 0.118
E12.8 With unspecified complications
0.000 0.882 0.118
E12.7 With multiple complications
0.000 0.882 0.118
E12.6 With other specified complications
0.000 0.882 0.118
E12.5 With peripheral circulatory complications
0.000 0.882 0.118
E12.4 With neurological complications
0.000 0.882 0.118
E12.3 With ophthalmic complications
0.000 0.882 0.118
E12.2 With renal complications
0.000 0.882 0.118
E12.1 With ketoacidosis
0.000 0.882 0.118
E12.0 With coma
0.000 0.882 0.118
E14.8 With unspecified complications
0.000 0.883 0.117
E85.9 Amyloidosis, unspecified
0.000 0.884 0.116
E16.2 Hypoglycaemia, unspecified
0.000 0.885 0.115
E88.2 Lipomatosis, not elsewhere classified
0.000 0.886 0.114
E14.1 With ketoacidosis
0.000 0.894 0.106
E46 Unspecified protein-energy malnutrition
0.000 0.895 0.105
E88.9 Metabolic disorder, unspecified
0.000 0.895 0.105
E88.8 Other specified metabolic disorders
0.000 0.895 0.105
E88.3 Tumour lysis syndrome
0.000 0.895 0.105
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.895 0.105
E15 Nondiabetic hypoglycaemic coma
0.000 0.899 0.100
E85.4 Organ-limited amyloidosis
0.000 0.899 0.100
E74 Other disorders of carbohydrate metabolism
0.000 0.900 0.100
E65-E68 Obesity and other hyperalimentation
0.000 0.900 0.100
E85.8 Other amyloidosis
0.000 0.902 0.098
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.902 0.098
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.902 0.098
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.902 0.098
E73 Lactose intolerance
0.000 0.905 0.095
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.906 0.094
E45 Retarded development following protein-energy malnutrition
0.000 0.906 0.094
E43 Unspecified severe protein-energy malnutrition
0.000 0.906 0.094
E42 Marasmic kwashiorkor
0.000 0.906 0.094
E41 Nutritional marasmus
0.000 0.906 0.094
E40 Kwashiorkor
0.000 0.906 0.094
E85.3 Secondary systemic amyloidosis
0.000 0.906 0.094
E11 Non-insulin-dependent diabetes mellitus
0.000 0.909 0.091
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.912 0.088
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.913 0.087
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.913 0.087
E16.4 Abnormal secretion of gastrin
0.000 0.913 0.087
E16.3 Increased secretion of glucagon
0.000 0.913 0.087
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.914 0.086
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.914 0.086
E70.3 Albinism
0.000 0.914 0.086
E70.2 Disorders of tyrosine metabolism
0.000 0.914 0.086
E70.1 Other hyperphenylalaninaemias
0.000 0.914 0.086
E70.0 Classical phenylketonuria
0.000 0.914 0.086
E71.3 Disorders of fatty-acid metabolism
0.000 0.914 0.086
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.914 0.086
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.914 0.086
E71.0 Maple-syrup-urine disease
0.000 0.914 0.086
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.914 0.086
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.914 0.086
E72.5 Disorders of glycine metabolism
0.000 0.914 0.086
E72.4 Disorders of ornithine metabolism
0.000 0.914 0.086
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.914 0.086
E72.2 Disorders of urea cycle metabolism
0.000 0.914 0.086
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.914 0.086
E72.0 Disorders of amino-acid transport
0.000 0.914 0.086
E75.6 Lipid storage disorder, unspecified
0.000 0.914 0.086
E75.5 Other lipid storage disorders
0.000 0.914 0.086
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.914 0.086
E75.3 Sphingolipidosis, unspecified
0.000 0.914 0.086
E75.2 Other sphingolipidosis
0.000 0.914 0.086
E75.1 Other gangliosidosis
0.000 0.914 0.086
E75.0 GM2 gangliosidosis
0.000 0.914 0.086
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.914 0.086
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.914 0.086
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.914 0.086
E76.2 Other mucopolysaccharidoses
0.000 0.914 0.086
E76.1 Mucopolysaccharidosis, type II
0.000 0.914 0.086
E76.0 Mucopolysaccharidosis, type I
0.000 0.914 0.086
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.914 0.086
E77.8 Other disorders of glycoprotein metabolism
0.000 0.914 0.086
E77.1 Defects in glycoprotein degradation
0.000 0.914 0.086
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.914 0.086
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.914 0.086
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.914 0.086
E79.1 Lesch-Nyhan syndrome
0.000 0.914 0.086
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.914 0.086
E84.9 Cystic fibrosis, unspecified
0.000 0.914 0.086
E84.8 Cystic fibrosis with other manifestations
0.000 0.914 0.086
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.914 0.086
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.914 0.086
E65 Localised adiposity
0.000 0.918 0.082
E50-E64 Other nutritional deficiencies
0.000 0.918 0.082
E11.5 With peripheral circulatory complications
0.000 0.920 0.080
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.923 0.077
E16.1 Other hypoglycaemia
0.000 0.924 0.075
E11.4 With neurological complications
0.000 0.928 0.072
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.928 0.072
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.928 0.072
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.928 0.072
E74.2 Disorders of galactose metabolism
0.000 0.928 0.072
E74.1 Disorders of fructose metabolism
0.000 0.928 0.072
E74.0 Glycogen storage disease
0.000 0.928 0.072
E67 Other hyperalimentation
0.000 0.928 0.072
E68 Sequelae of hyperalimentation
0.000 0.928 0.072
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.931 0.069
E14.9 Without complications
0.000 0.931 0.069
E73.8 Other lactose intolerance
0.000 0.932 0.068
E73.1 Secondary lactase deficiency
0.000 0.932 0.068
E73.0 Congenital lactase deficiency
0.000 0.932 0.068
E44.1 Mild protein-energy malnutrition
0.000 0.932 0.067
E44.0 Moderate protein-energy malnutrition
0.000 0.932 0.067
M41.9 Scoliosis, unspecified
0.067 0.933 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.066 0.934 0.000
E11.7 With multiple complications
0.000 0.935 0.065
E11.1 With ketoacidosis
0.000 0.936 0.064
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.936 0.064
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.937 0.063
E80.5 Crigler-Najjar syndrome
0.000 0.937 0.063
E80.3 Defects of catalase and peroxydase
0.000 0.937 0.063
E80.1 Porphyria cutanea tarda
0.000 0.937 0.063
E80.0 Hereditary erythropoietic porphyria
0.000 0.937 0.063
E53 Deficiency of other B group vitamins
0.000 0.937 0.063
E11.8 With unspecified complications
0.000 0.939 0.061
M41.99 Scoliosis, unspecified (Site unspecified)
0.061 0.939 0.000
E11.0 With coma
0.000 0.939 0.060
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.060 0.940 0.000
E11.3 With ophthalmic complications
0.000 0.941 0.059
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.941 0.059
E63 Other nutritional deficiencies
0.000 0.941 0.059
E56 Other vitamin deficiencies
0.000 0.941 0.059
E50 Vitamin A deficiency
0.000 0.941 0.059
E60 Dietary zinc deficiency
0.000 0.941 0.059
E59 Dietary selenium deficiency
0.000 0.941 0.059
E58 Dietary calcium deficiency
0.000 0.941 0.059
E54 Ascorbic acid deficiency
0.000 0.941 0.059
E52 Niacin deficiency [pellagra]
0.000 0.941 0.059
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.942 0.058
M41.94 Scoliosis, unspecified (Thoracic region)
0.058 0.942 0.000
E80.6 Other disorders of bilirubin metabolism
0.000 0.943 0.057
E80.2 Other porphyria
0.000 0.943 0.057
E11.2 With renal complications
0.000 0.945 0.055
E11.6 With other specified complications
0.000 0.946 0.054
E78.4 Other hyperlipidaemia
0.000 0.947 0.053
E51 Thiamine deficiency
0.000 0.947 0.052
E53.8 Deficiency of other specified B group vitamins
0.000 0.948 0.052
E00-E07 Disorders of thyroid gland
0.000 0.948 0.052
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.948 0.051
E67.8 Other specified hyperalimentation
0.000 0.948 0.052
E67.3 Hypervitaminosis D
0.000 0.948 0.052
E67.2 Megavitamin-B6 syndrome
0.000 0.948 0.052
E67.1 Hypercarotenaemia
0.000 0.948 0.052
E67.0 Hypervitaminosis A
0.000 0.948 0.052
E80.4 Gilbert's syndrome
0.000 0.948 0.052
E20-E35 Disorders of other endocrine glands
0.000 0.948 0.052
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.950 0.050
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.950 0.050
E89.5 Postprocedural testicular hypofunction
0.000 0.950 0.050
E89.4 Postprocedural ovarian failure
0.000 0.950 0.050
E89.1 Postprocedural hypoinsulinaemia
0.000 0.950 0.050
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.050 0.950 0.000
E78.1 Pure hyperglyceridaemia
0.000 0.951 0.049
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.951 0.049
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.049 0.951 0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.048 0.952 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.048 0.952 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.048 0.952 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.048 0.952 0.000
E55 Vitamin D deficiency
0.000 0.952 0.048
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.952 0.048
E78.6 Lipoprotein deficiency
0.000 0.954 0.046
E78.3 Hyperchylomicronaemia
0.000 0.954 0.046
M41 Scoliosis
0.046 0.954 0.000
E89.2 Postprocedural hypoparathyroidism
0.000 0.954 0.046
E78.2 Mixed hyperlipidaemia
0.000 0.954 0.046
E53.1 Pyridoxine deficiency
0.000 0.954 0.045
E53.0 Riboflavin deficiency
0.000 0.954 0.045
E20 Hypoparathyroidism
0.000 0.955 0.045
E89.0 Postprocedural hypothyroidism
0.000 0.957 0.043
E73.9 Lactose intolerance, unspecified
0.001 0.957 0.042
E50.9 Vitamin A deficiency, unspecified
0.000 0.958 0.042
E50.8 Other manifestations of vitamin A deficiency
0.000 0.958 0.042
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.958 0.042
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.958 0.042
E50.5 Vitamin A deficiency with night blindness
0.000 0.958 0.042
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.958 0.042
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.958 0.042
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.958 0.042
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.958 0.042
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.958 0.042
E56.9 Vitamin deficiency, unspecified
0.000 0.958 0.042
E56.8 Deficiency of other vitamins
0.000 0.958 0.042
E56.1 Deficiency of vitamin K
0.000 0.958 0.042
E56.0 Deficiency of vitamin E
0.000 0.958 0.042
E63.9 Nutritional deficiency, unspecified
0.000 0.958 0.042
E63.8 Other specified nutritional deficiencies
0.000 0.958 0.042
E63.1 Imbalance of constituents of food intake
0.000 0.958 0.042
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.958 0.042
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.958 0.042
E64.8 Sequelae of other nutritional deficiencies
0.000 0.958 0.042
E64.3 Sequelae of rickets
0.000 0.958 0.042
E64.2 Sequelae of vitamin C deficiency
0.000 0.958 0.042
E64.1 Sequelae of vitamin A deficiency
0.000 0.958 0.042
E64.0 Sequelae of protein-energy malnutrition
0.000 0.958 0.042
E04 Other non-toxic goitre
0.000 0.958 0.042
E61 Deficiency of other nutrient elements
0.000 0.958 0.041
E53.9 Vitamin B deficiency, unspecified
0.000 0.958 0.041
E87.3 Alkalosis
0.000 0.959 0.041
E87.0 Hyperosmolality and hypernatraemia
0.000 0.959 0.041
E28 Ovarian dysfunction
0.000 0.960 0.040
E20.9 Hypoparathyroidism, unspecified
0.000 0.960 0.040
E51.9 Thiamine deficiency, unspecified
0.000 0.962 0.038
E51.8 Other manifestations of thiamine deficiency
0.000 0.962 0.038
E51.1 Beriberi
0.000 0.962 0.038
E24 Cushing's syndrome
0.000 0.962 0.038
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.962 0.038
E00 Congenital iodine-deficiency syndrome
0.000 0.962 0.038
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.963 0.037
E32 Diseases of thymus
0.000 0.963 0.037
E31 Polyglandular dysfunction
0.000 0.963 0.037
E30 Disorders of puberty, not elsewhere classified
0.000 0.963 0.037
E25 Adrenogenital disorders
0.000 0.963 0.037
E07 Other disorders of thyroid
0.000 0.963 0.037
E87.7 Fluid overload
0.000 0.964 0.036
E87.4 Mixed disorder of acid-base balance
0.000 0.965 0.035
E29 Testicular dysfunction
0.000 0.965 0.035
E04.9 Non-toxic goitre, unspecified
0.000 0.965 0.035
E04.2 Non-toxic multinodular goitre
0.000 0.965 0.035
E55.0 Rickets, active
0.000 0.965 0.034
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.965 0.035
E34 Other endocrine disorders
0.000 0.966 0.034
E06 Thyroiditis
0.000 0.966 0.034
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.966 0.033
M41.5 Other secondary scoliosis
0.033 0.967 0.000
M41.4 Neuromuscular scoliosis
0.033 0.967 0.000
M41.3 Thoracogenic scoliosis
0.033 0.967 0.000
M41.2 Other idiopathic scoliosis
0.033 0.967 0.000
M41.1 Juvenile idiopathic scoliosis
0.033 0.967 0.000
M41.0 Infantile idiopathic scoliosis
0.033 0.967 0.000
E26 Hyperaldosteronism
0.000 0.967 0.033
E23 Hypofunction and other disorders of pituitary gland
0.000 0.967 0.033
E87.2 Acidosis
0.000 0.967 0.033
M40-M43 Deforming dorsopathies
0.033 0.967 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.967 0.033
E20.8 Other hypoparathyroidism
0.000 0.968 0.032
E20.1 Pseudohypoparathyroidism
0.000 0.968 0.032
E20.0 Idiopathic hypoparathyroidism
0.000 0.968 0.032
E51.2 Wernicke's encephalopathy
0.000 0.968 0.031
M41.8 Other forms of scoliosis
0.032 0.968 0.000
E78.8 Other disorders of lipoprotein metabolism
0.000 0.969 0.031
E28.3 Primary ovarian failure
0.000 0.969 0.031
M43 Other deforming dorsopathies
0.030 0.969 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.969 0.030
E04.8 Other specified non-toxic goitre
0.000 0.970 0.030
E89.3 Postprocedural hypopituitarism
0.000 0.970 0.030
E61.9 Deficiency of nutrient element, unspecified
0.000 0.970 0.030
E61.8 Deficiency of other specified nutrient elements
0.000 0.970 0.030
E61.7 Deficiency of multiple nutrient elements
0.000 0.970 0.030
E61.6 Vanadium deficiency
0.000 0.970 0.030
E61.5 Molybdenum deficiency
0.000 0.970 0.030
E61.4 Chromium deficiency
0.000 0.970 0.030
E61.3 Manganese deficiency
0.000 0.970 0.030
E61.0 Copper deficiency
0.000 0.970 0.030
E28.9 Ovarian dysfunction, unspecified
0.000 0.971 0.029
E28.8 Other ovarian dysfunction
0.000 0.971 0.029
E28.1 Androgen excess
0.000 0.971 0.029
E28.0 Oestrogen excess
0.000 0.971 0.029
E87.5 Hyperkalaemia
0.000 0.971 0.029
E61.2 Magnesium deficiency
0.000 0.972 0.027
E24.9 Cushing's syndrome, unspecified
0.000 0.972 0.028
M43.1 Spondylolisthesis
0.027 0.973 0.000
E07.8 Other specified disorders of thyroid
0.000 0.973 0.027
E24.8 Other Cushing's syndrome
0.000 0.973 0.027
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.973 0.027
E24.3 Ectopic ACTH syndrome
0.000 0.973 0.027
E24.2 Drug-induced Cushing's syndrome
0.000 0.973 0.027
E24.1 Nelson's syndrome
0.000 0.973 0.027
E24.0 Pituitary-dependent Cushing's disease
0.000 0.973 0.027
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.973 0.027
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.973 0.027
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.973 0.027
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.973 0.027
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.973 0.027
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.973 0.027
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.973 0.027
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.973 0.027
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.973 0.027
E25.9 Adrenogenital disorder, unspecified
0.000 0.973 0.027
E25.8 Other adrenogenital disorders
0.000 0.973 0.027
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.973 0.027
E30.9 Disorder of puberty, unspecified
0.000 0.973 0.027
E30.8 Other disorders of puberty
0.000 0.973 0.027
E30.1 Precocious puberty
0.000 0.973 0.027
E30.0 Delayed puberty
0.000 0.973 0.027
E31.9 Polyglandular dysfunction, unspecified
0.000 0.973 0.027
E31.8 Other polyglandular dysfunction
0.000 0.973 0.027
E31.1 Polyglandular hyperfunction
0.000 0.973 0.027
E31.0 Autoimmune polyglandular failure
0.000 0.973 0.027
E32.9 Disease of thymus, unspecified
0.000 0.973 0.027
E32.8 Other diseases of thymus
0.000 0.973 0.027
E32.1 Abscess of thymus
0.000 0.973 0.027
E32.0 Persistent hyperplasia of thymus
0.000 0.973 0.027
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.973 0.027
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.973 0.027
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.973 0.027
E66 Obesity
0.000 0.973 0.027
E07.1 Dyshormogenetic goitre
0.000 0.973 0.026
E07.0 Hypersecretion of calcitonin
0.000 0.973 0.026
E27 Other disorders of adrenal gland
0.000 0.973 0.026
M43.6 Torticollis
0.026 0.974 0.000
E23.2 Diabetes insipidus
0.000 0.974 0.026
E29.9 Testicular dysfunction, unspecified
0.000 0.975 0.025
E29.8 Other testicular dysfunction
0.000 0.975 0.025
E29.0 Testicular hyperfunction
0.000 0.975 0.025
M43.16 Spondylolisthesis (Lumbar region)
0.025 0.975 0.000
E34.5 Androgen resistance syndrome
0.000 0.975 0.024
E34.4 Constitutional tall stature
0.000 0.975 0.024
E34.3 Short stature, not elsewhere classified
0.000 0.975 0.024
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.975 0.024
E34.1 Other hypersecretion of intestinal hormones
0.000 0.975 0.024
M40 Kyphosis and lordosis
0.024 0.976 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.976 0.024
E06.5 Other chronic thyroiditis
0.000 0.976 0.024
E06.4 Drug-induced thyroiditis
0.000 0.976 0.024
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.976 0.024
E06.1 Subacute thyroiditis
0.000 0.976 0.024
E06.0 Acute thyroiditis
0.000 0.976 0.024
E34.9 Endocrine disorder, unspecified
0.000 0.976 0.024
M41.09 Infantile idiopathic scoliosis (Site unspecified)
0.024 0.976 0.000
M41.08 Infantile idiopathic scoliosis (Sacral and sacrococcygeal region)
0.024 0.976 0.000
M41.07 Infantile idiopathic scoliosis (Lumbosacral region)
0.024 0.976 0.000
M41.06 Infantile idiopathic scoliosis (Lumbar region)
0.024 0.976 0.000
M41.05 Infantile idiopathic scoliosis (Thoracolumbar region)
0.024 0.976 0.000
M41.04 Infantile idiopathic scoliosis (Thoracic region)
0.024 0.976 0.000
M41.03 Infantile idiopathic scoliosis (Cervicothoracic region)
0.024 0.976 0.000
M41.02 Infantile idiopathic scoliosis (Cervical region)
0.024 0.976 0.000
M41.01 Infantile idiopathic scoliosis (Occipito-atlanto-axial region)
0.024 0.976 0.000
M41.00 Infantile idiopathic scoliosis (Multiple sites in spine)
0.024 0.976 0.000
M41.19 Juvenile idiopathic scoliosis (Site unspecified)
0.024 0.976 0.000
M41.18 Juvenile idiopathic scoliosis (Sacral and sacrococcygeal region)
0.024 0.976 0.000
M41.17 Juvenile idiopathic scoliosis (Lumbosacral region)
0.024 0.976 0.000
M41.16 Juvenile idiopathic scoliosis (Lumbar region)
0.024 0.976 0.000
M41.15 Juvenile idiopathic scoliosis (Thoracolumbar region)
0.024 0.976 0.000
M41.14 Juvenile idiopathic scoliosis (Thoracic region)
0.024 0.976 0.000
M41.13 Juvenile idiopathic scoliosis (Cervicothoracic region)
0.024 0.976 0.000
M41.12 Juvenile idiopathic scoliosis (Cervical region)
0.024 0.976 0.000
M41.11 Juvenile idiopathic scoliosis (Occipito-atlanto-axial region)
0.024 0.976 0.000
M41.10 Juvenile idiopathic scoliosis (Multiple sites in spine)
0.024 0.976 0.000
M41.29 Other idiopathic scoliosis (Site unspecified)
0.024 0.976 0.000
M41.28 Other idiopathic scoliosis (Sacral and sacrococcygeal region)
0.024 0.976 0.000
M41.27 Other idiopathic scoliosis (Lumbosacral region)
0.024 0.976 0.000
M41.26 Other idiopathic scoliosis (Lumbar region)
0.024 0.976 0.000
M41.25 Other idiopathic scoliosis (Thoracolumbar region)
0.024 0.976 0.000
M41.24 Other idiopathic scoliosis (Thoracic region)
0.024 0.976 0.000
M41.23 Other idiopathic scoliosis (Cervicothoracic region)
0.024 0.976 0.000
M41.22 Other idiopathic scoliosis (Cervical region)
0.024 0.976 0.000
M41.21 Other idiopathic scoliosis (Occipito-atlanto-axial region)
0.024 0.976 0.000
M41.20 Other idiopathic scoliosis (Multiple sites in spine)
0.024 0.976 0.000
M41.39 Thoracogenic scoliosis-Site unspe
0.024 0.976 0.000
M41.38 Thoracogenic scoliosis-Sacral/sacrococ
0.024 0.976 0.000
M41.37 Thoracogenic scoliosis-Lumbosacral
0.024 0.976 0.000
M41.36 Thoracogenic scoliosis-Lumbar
0.024 0.976 0.000
M41.35 Thoracogenic scoliosis (Thoracolumbar region)
0.024 0.976 0.000
M41.34 Thoracogenic scoliosis (Thoracic region)
0.024 0.976 0.000
M41.33 Thoracogenic scoliosis (Cervicothoracic region)
0.024 0.976 0.000
M41.32 Thoracogenic scoliosis-Cervical
0.024 0.976 0.000
M41.31 Thoracogenic scoliosis-Occipit-atl-axl
0.024 0.976 0.000
M41.30 Thoracogenic scoliosis (Multiple sites in spine)
0.024 0.976 0.000
M41.49 Neuromuscular scoliosis (Site unspecified)
0.024 0.976 0.000
M41.48 Neuromuscular scoliosis (Sacral and sacrococcygeal region)
0.024 0.976 0.000
M41.47 Neuromuscular scoliosis (Lumbosacral region)
0.024 0.976 0.000
M41.46 Neuromuscular scoliosis (Lumbar region)
0.024 0.976 0.000
M41.45 Neuromuscular scoliosis (Thoracolumbar region)
0.024 0.976 0.000
M41.44 Neuromuscular scoliosis (Thoracic region)
0.024 0.976 0.000
M41.43 Neuromuscular scoliosis (Cervicothoracic region)
0.024 0.976 0.000
M41.42 Neuromuscular scoliosis (Cervical region)
0.024 0.976 0.000
M41.41 Neuromuscular scoliosis (Occipito-atlanto-axial region)
0.024 0.976 0.000
M41.40 Neuromuscular scoliosis (Multiple sites in spine)
0.024 0.976 0.000
M41.59 Other secondary scoliosis (Site unspecified)
0.024 0.976 0.000
M41.58 Other secondary scoliosis (Sacral and sacrococcygeal region)
0.024 0.976 0.000
M41.57 Other secondary scoliosis (Lumbosacral region)
0.024 0.976 0.000
M41.56 Other secondary scoliosis (Lumbar region)
0.024 0.976 0.000
M41.55 Other secondary scoliosis (Thoracolumbar region)
0.024 0.976 0.000
M41.54 Other secondary scoliosis (Thoracic region)
0.024 0.976 0.000
M41.53 Other secondary scoliosis (Cervicothoracic region)
0.024 0.976 0.000
M41.52 Other secondary scoliosis (Cervical region)
0.024 0.976 0.000
M41.51 Other secondary scoliosis (Occipito-atlanto-axial region)
0.024 0.976 0.000
M41.50 Other secondary scoliosis (Multiple sites in spine)
0.024 0.976 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.976 0.024
E26.8 Other hyperaldosteronism
0.000 0.976 0.024
E26.1 Secondary hyperaldosteronism
0.000 0.976 0.024
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.976 0.024
E23.1 Drug-induced hypopituitarism
0.000 0.976 0.024
E23.7 Disorder of pituitary gland, unspecified
0.000 0.976 0.024
M42 Spinal osteochondrosis
0.024 0.976 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.976 0.024
M43.62 Torticollis-Cervical
0.023 0.976 0.000
E86 Volume depletion
0.000 0.977 0.023
E23.6 Other disorders of pituitary gland
0.000 0.977 0.023
E34.8 Other specified endocrine disorders
0.000 0.977 0.023
E34.0 Carcinoid syndrome
0.000 0.977 0.023
E06.9 Thyroiditis, unspecified
0.000 0.977 0.023
M41.89 Other forms of scoliosis (Site unspecified)
0.023 0.977 0.000
M41.88 Other forms of scoliosis (Sacral and sacrococcygeal region)
0.023 0.977 0.000
M41.87 Other forms of scoliosis (Lumbosacral region)
0.023 0.977 0.000
M41.85 Other forms of scoliosis (Thoracolumbar region)
0.023 0.977 0.000
M41.84 Other forms of scoliosis (Thoracic region)
0.023 0.977 0.000
M41.83 Other forms of scoliosis (Cervicothoracic region)
0.023 0.977 0.000
M41.82 Other forms of scoliosis (Cervical region)
0.023 0.977 0.000
M41.81 Other forms of scoliosis (Occipito-atlanto-axial region)
0.023 0.977 0.000
M41.80 Other forms of scoliosis (Multiple sites in spine)
0.023 0.977 0.000
E29.1 Testicular hypofunction
0.000 0.977 0.023
E21.3 Hyperparathyroidism, unspecified
0.000 0.977 0.023
M43.9 Deforming dorsopathy, unspecified
0.022 0.978 0.000
M43.8 Other specified deforming dorsopathies
0.022 0.978 0.000
M43.5 Other recurrent vertebral subluxation
0.022 0.978 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.022 0.978 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.022 0.978 0.000
M43.2 Other fusion of spine
0.022 0.978 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.978 0.022
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.978 0.022
E06.3 Autoimmune thyroiditis
0.000 0.978 0.022
M43.17 Spondylolisthesis (Lumbosacral region)
0.021 0.978 0.000
M41.86 Other forms of scoliosis (Lumbar region)
0.021 0.979 0.000
M43.0 Spondylolysis
0.021 0.979 0.000
E26.0 Primary hyperaldosteronism
0.000 0.980 0.020
M43.12 Spondylolisthesis (Cervical region)
0.020 0.980 0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)
0.020 0.980 0.000
M43.15 Spondylolisthesis (Thoracolumbar region)
0.020 0.980 0.000
M43.14 Spondylolisthesis (Thoracic region)
0.020 0.980 0.000
M43.13 Spondylolisthesis (Cervicothoracic region)
0.020 0.980 0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)
0.020 0.980 0.000
M43.10 Spondylolisthesis (Multiple sites in spine)
0.020 0.980 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.980 0.020
E21.2 Other hyperparathyroidism
0.000 0.980 0.020
E22 Hyperfunction of pituitary gland
0.000 0.980 0.019
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.980 0.019
E03 Other hypothyroidism
0.000 0.981 0.019
E66.1 Drug-induced obesity
0.000 0.981 0.019
E27.5 Adrenomedullary hyperfunction
0.000 0.981 0.019

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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