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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12212507
log Bayes Factor = 8.99
Chromosome 6   position 161,071,982  (GRCh37) Explore rs12212507 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.001 0.999
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.001 0.999
I20 Angina pectoris
0.000 0.002 0.998
I25.2 Old myocardial infarction
0.000 0.002 0.998
I20.9 Angina pectoris, unspecified
0.000 0.018 0.982
Chapter IX Diseases of the circulatory system
0.000 0.028 0.972
I20.0 Unstable angina
0.000 0.032 0.968
I60-I69 Cerebrovascular diseases
0.000 0.036 0.964
Chapter II Neoplasms
0.950 0.050 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.949 0.051 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.946 0.054 0.000
I30-I52 Other forms of heart disease
0.000 0.058 0.942
I51 Complications and ill-defined descriptions of heart disease
0.000 0.062 0.938
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.065 0.935
I51.8 Other ill-defined heart diseases
0.000 0.067 0.933
C50-C50 Malignant neoplasm of breast
0.930 0.070 0.000
I50 Heart failure
0.000 0.078 0.922
C77.9 Lymph node, unspecified
0.917 0.083 0.000
C50 Malignant neoplasm of breast
0.915 0.085 0.000
D00-D09 In situ neoplasms
0.910 0.090 0.000
C60-C63 Malignant neoplasms of male genital organs
0.905 0.095 0.000
I05-I09 Chronic rheumatic heart diseases
0.000 0.103 0.897
C77.3 Axillary and upper limb lymph nodes
0.894 0.106 0.000
C15-C26 Malignant neoplasms of digestive organs
0.889 0.111 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.882 0.118 0.000
C61 Malignant neoplasm of prostate
0.881 0.119 0.000
C50.4 Upper-outer quadrant of breast
0.875 0.125 0.000
D04 Carcinoma in situ of skin
0.874 0.126 0.000
C15 Malignant neoplasm of oesophagus
0.870 0.130 0.000
I50.1 Left ventricular failure
0.000 0.133 0.867
I20.8 Other forms of angina pectoris
0.000 0.133 0.866
C78.7 Secondary malignant neoplasm of liver
0.860 0.140 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.860 0.140 0.000
I51.9 Heart disease, unspecified
0.000 0.147 0.853
I24 Other acute ischaemic heart diseases
0.000 0.151 0.849
C51-C58 Malignant neoplasms of female genital organs
0.844 0.156 0.000
D03 Melanoma in situ
0.841 0.159 0.000
I25.5 Ischaemic cardiomyopathy
0.000 0.160 0.840
I63 Cerebral infarction
0.000 0.165 0.835
I35 Nonrheumatic aortic valve disorders
0.000 0.168 0.832
C77.8 Lymph nodes of multiple regions
0.829 0.171 0.000
I69 Sequelae of cerebrovascular disease
0.000 0.172 0.828
I50.9 Heart failure, unspecified
0.000 0.179 0.821
C15.9 Oesophagus, unspecified
0.819 0.181 0.000
I21 Acute myocardial infarction
0.000 0.189 0.811
I08 Multiple valve diseases
0.000 0.196 0.804
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.199 0.801
D37-D48 Neoplasms of uncertain or unknown behaviour
0.800 0.200 0.000
I63.9 Cerebral infarction, unspecified
0.000 0.204 0.796
C50.5 Lower-outer quadrant of breast
0.794 0.206 0.000
C78.0 Secondary malignant neoplasm of lung
0.788 0.212 0.000
C15.5 Lower third of oesophagus
0.788 0.212 0.000
C77.2 Intra-abdominal lymph nodes
0.787 0.213 0.000
C50.1 Central portion of breast
0.786 0.214 0.000
C77.0 Lymph nodes of head, face and neck
0.774 0.226 0.000
I07 Rheumatic tricuspid valve diseases
0.000 0.228 0.771
I67 Other cerebrovascular diseases
0.000 0.232 0.768
C50.9 Breast, unspecified
0.765 0.235 0.000
D04.7 Skin of lower limb, including hip
0.762 0.238 0.000
I35.0 Aortic (valve) stenosis
0.000 0.239 0.761
I33 Acute and subacute endocarditis
0.000 0.248 0.752
I62 Other nontraumatic intracranial haemorrhage
0.000 0.248 0.752
I25.3 Aneurysm of heart
0.000 0.248 0.752
I50.0 Congestive heart failure
0.000 0.249 0.751
C26 Malignant neoplasm of other and ill-defined digestive organs
0.748 0.252 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.740 0.260 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.740 0.260 0.000
D04.6 Skin of upper limb, including shoulder
0.738 0.262 0.000
D03.5 Melanoma in situ of trunk
0.735 0.265 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.277 0.723
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.278 0.722
I69.3 Sequelae of cerebral infarction
0.000 0.279 0.721
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.720 0.280 0.000
I22 Subsequent myocardial infarction
0.000 0.282 0.718
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I25.4 Coronary artery aneurysm
0.000 0.283 0.717
I23 Certain current complications following acute myocardial infarction
0.000 0.283 0.717
C23 Malignant neoplasm of gallbladder
0.713 0.287 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.709 0.291 0.000
I67.8 Other specified cerebrovascular diseases
0.000 0.292 0.708
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.293 0.707
C16 Malignant neoplasm of stomach
0.704 0.296 0.000
I51.6 Cardiovascular disease, unspecified
0.000 0.298 0.702
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.298 0.702
D04.5 Skin of trunk
0.699 0.301 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.302 0.698
D03.7 Melanoma in situ of lower limb, including hip
0.698 0.302 0.000
I00-I02 Acute rheumatic fever
0.000 0.303 0.697
D06 Carcinoma in situ of cervix uteri
0.692 0.308 0.000
C50.0 Nipple and areola
0.692 0.308 0.000
I08.0 Disorders of both mitral and aortic valves
0.000 0.308 0.692
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.309 0.691
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.309 0.691
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.689 0.311 0.000
D04.4 Skin of scalp and neck
0.688 0.312 0.000
C09 Malignant neoplasm of tonsil
0.687 0.313 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.687 0.313 0.000
I65.2 Occlusion and stenosis of carotid artery
0.000 0.315 0.685
D04.3 Skin of other and unspecified parts of face
0.682 0.318 0.000
I07.1 Tricuspid insufficiency
0.000 0.318 0.682
C40-C41 Malignant neoplasms of bone and articular cartilage
0.681 0.318 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.680 0.320 0.000
I35.8 Other aortic valve disorders
0.000 0.321 0.679
C80 Malignant neoplasm without specification of site
0.676 0.324 0.000
I52 Other heart disorders in diseases classified elsewhere
0.000 0.325 0.675
I48 Atrial fibrillation and flutter
0.000 0.325 0.675
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.325 0.675
I41 Myocarditis in diseases classified elsewhere
0.000 0.325 0.675
I40 Acute myocarditis
0.000 0.325 0.675
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.325 0.675
I32 Pericarditis in diseases classified elsewhere
0.000 0.325 0.675
I51.5 Myocardial degeneration
0.000 0.327 0.673
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.327 0.673
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.327 0.673
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.327 0.673
I31 Other diseases of pericardium
0.000 0.328 0.672
C15.4 Middle third of oesophagus
0.672 0.328 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.328 0.672
I51.7 Cardiomegaly
0.000 0.329 0.671
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.329 0.670
C77.4 Inguinal and lower limb lymph nodes
0.668 0.332 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.333 0.667
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.667 0.333 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.666 0.334 0.000
C10 Malignant neoplasm of oropharynx
0.666 0.334 0.000
I36 Nonrheumatic tricuspid valve disorders
0.000 0.336 0.664
C17 Malignant neoplasm of small intestine
0.663 0.336 0.000
I05 Rheumatic mitral valve diseases
0.000 0.337 0.663
C53 Malignant neoplasm of cervix uteri
0.661 0.339 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.658 0.342 0.000
C50.6 Axillary tail of breast
0.656 0.344 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.346 0.654
D01 Carcinoma in situ of other and unspecified digestive organs
0.652 0.347 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.652 0.347 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.652 0.348 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.649 0.351 0.000
C60 Malignant neoplasm of penis
0.649 0.351 0.000
C26.0 Intestinal tract, part unspecified
0.647 0.353 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.646 0.354 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.355 0.645
D02 Carcinoma in situ of middle ear and respiratory system
0.645 0.355 0.000
I51.4 Myocarditis, unspecified
0.000 0.355 0.645
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.356 0.644
C50.3 Lower-inner quadrant of breast
0.644 0.356 0.000
I06 Rheumatic aortic valve diseases
0.000 0.357 0.643
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.357 0.643
C52 Malignant neoplasm of vagina
0.642 0.358 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.637 0.363 0.000
C64-C68 Malignant neoplasms of urinary tract
0.637 0.363 0.000
C56 Malignant neoplasm of ovary
0.634 0.366 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.367 0.633
I08.8 Other multiple valve diseases
0.000 0.367 0.633
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.632 0.368 0.000
C78.2 Secondary malignant neoplasm of pleura
0.629 0.371 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.627 0.373 0.000
D04.9 Skin, unspecified
0.627 0.373 0.000
D04.8 Skin of other sites
0.627 0.373 0.000
D04.2 Skin of ear and external auricular canal
0.627 0.373 0.000
D04.1 Skin of eyelid, including canthus
0.627 0.373 0.000
D04.0 Skin of lip
0.627 0.373 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.625 0.374 0.000
C04 Malignant neoplasm of floor of mouth
0.625 0.375 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.625 0.375 0.000
C15.8 Overlapping lesion of oesophagus
0.624 0.376 0.000
C15.3 Upper third of oesophagus
0.624 0.376 0.000
C15.2 Abdominal part of oesophagus
0.624 0.376 0.000
C15.1 Thoracic part of oesophagus
0.624 0.376 0.000
C15.0 Cervical part of oesophagus
0.624 0.376 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.377 0.623
D09 Carcinoma in situ of other and unspecified sites
0.619 0.380 0.000
C13 Malignant neoplasm of hypopharynx
0.616 0.384 0.000
C11 Malignant neoplasm of nasopharynx
0.616 0.384 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.616 0.384 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.616 0.384 0.000
C05 Malignant neoplasm of palate
0.616 0.384 0.000
C03 Malignant neoplasm of gum
0.616 0.384 0.000
C00 Malignant neoplasm of lip
0.616 0.384 0.000
C12 Malignant neoplasm of pyriform sinus
0.616 0.384 0.000
C07 Malignant neoplasm of parotid gland
0.616 0.384 0.000
I33.0 Acute and subacute infective endocarditis
0.000 0.384 0.616
I30 Acute pericarditis
0.000 0.384 0.616
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.613 0.387 0.000
I24.1 Dressler's syndrome
0.000 0.391 0.609
C02.9 Tongue, unspecified
0.608 0.391 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.392 0.608
C78.1 Secondary malignant neoplasm of mediastinum
0.607 0.393 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.606 0.394 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.605 0.395 0.000
C58 Malignant neoplasm of placenta
0.605 0.395 0.000
C01 Malignant neoplasm of base of tongue
0.605 0.395 0.000
C02.1 Border of tongue
0.604 0.396 0.000
D03.9 Melanoma in situ, unspecified
0.603 0.397 0.000
D03.8 Melanoma in situ of other sites
0.603 0.397 0.000
D03.4 Melanoma in situ of scalp and neck
0.603 0.397 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.603 0.397 0.000
D03.1 Melanoma in situ of eyelid, including canthus
0.603 0.397 0.000
D03.0 Melanoma in situ of lip
0.603 0.397 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.402 0.598
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.402 0.598
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.402 0.598
D48.1 Connective and other soft tissue
0.598 0.402 0.000
I24.8 Other forms of acute ischaemic heart disease
0.000 0.405 0.595
I77 Other disorders of arteries and arterioles
0.000 0.405 0.595
I63.8 Other cerebral infarction
0.000 0.406 0.594
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.406 0.593
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.406 0.593
D37.0 Lip, oral cavity and pharynx
0.593 0.407 0.000
I61 Intracerebral haemorrhage
0.000 0.411 0.589
C20 Malignant neoplasm of rectum
0.588 0.412 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.587 0.412 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.413 0.587
C21 Malignant neoplasm of anus and anal canal
0.586 0.414 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.414 0.586
I37 Pulmonary valve disorders
0.000 0.415 0.585
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.418 0.582
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.418 0.582
C51 Malignant neoplasm of vulva
0.581 0.419 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.420 0.580
Z95.1 Presence of aortocoronary bypass graft
0.000 0.422 0.578
I08.9 Multiple valve disease, unspecified
0.000 0.424 0.576
I42 Cardiomyopathy
0.000 0.424 0.576
I09 Other rheumatic heart diseases
0.000 0.425 0.575
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.425 0.574
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.425 0.574
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.425 0.574
I65.1 Occlusion and stenosis of basilar artery
0.000 0.425 0.574
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.425 0.574
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.574 0.425 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.573 0.427 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.573 0.427 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.573 0.427 0.000
I74 Arterial embolism and thrombosis
0.000 0.428 0.572
I27 Other pulmonary heart diseases
0.000 0.429 0.571
D39.1 Ovary
0.571 0.429 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.570 0.429 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.570 0.430 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.431 0.569
C62 Malignant neoplasm of testis
0.566 0.434 0.000
I46 Cardiac arrest
0.000 0.435 0.565
C54 Malignant neoplasm of corpus uteri
0.564 0.436 0.000
I77.1 Stricture of artery
0.000 0.436 0.564
C09.9 Tonsil, unspecified
0.563 0.437 0.000
C50.2 Upper-inner quadrant of breast
0.562 0.438 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.440 0.560
D37.2 Small intestine
0.559 0.441 0.000
I51.0 Cardiac septal defect, acquired
0.000 0.442 0.557
Z95.2 Presence of prosthetic heart valve
0.000 0.443 0.557
I07.9 Tricuspid valve disease, unspecified
0.000 0.447 0.553
I07.8 Other tricuspid valve diseases
0.000 0.447 0.553
I07.2 Tricuspid stenosis with insufficiency
0.000 0.447 0.553
I07.0 Tricuspid stenosis
0.000 0.447 0.553
C16.0 Cardia
0.553 0.447 0.000
I67.9 Cerebrovascular disease, unspecified
0.000 0.448 0.552
C69 Malignant neoplasm of eye and adnexa
0.551 0.448 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.449 0.551
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.449 0.551
I67.5 Moyamoya disease
0.000 0.449 0.551
I67.4 Hypertensive encephalopathy
0.000 0.449 0.551
I67.3 Progressive vascular leukoencephalopathy
0.000 0.449 0.551
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.449 0.551
Z95.0 Presence of cardiac pacemaker
0.000 0.452 0.548
C77.1 Intrathoracic lymph nodes
0.544 0.455 0.000
I67.2 Cerebral atherosclerosis
0.000 0.456 0.544
I33.9 Acute endocarditis, unspecified
0.000 0.461 0.539
I62.1 Nontraumatic extradural haemorrhage
0.000 0.461 0.539
C26.9 Ill-defined sites within the digestive system
0.536 0.464 0.000
C26.8 Overlapping lesion of digestive system
0.536 0.464 0.000
C26.1 Spleen
0.536 0.464 0.000
D06.9 Cervix, unspecified
0.536 0.464 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.535 0.465 0.000
I34 Nonrheumatic mitral valve disorders
0.000 0.467 0.533
C02.8 Overlapping lesion of tongue
0.531 0.469 0.000
C02.4 Lingual tonsil
0.531 0.469 0.000
C02.3 Anterior two-thirds of tongue, part unspecified
0.531 0.469 0.000
C02.2 Ventral surface of tongue
0.531 0.469 0.000
C02.0 Dorsal surface of tongue
0.531 0.469 0.000
C53.9 Cervix uteri, unspecified
0.530 0.470 0.000
D05 Carcinoma in situ of breast
0.530 0.470 0.000
C10.9 Oropharynx, unspecified
0.528 0.472 0.000
I20.1 Angina pectoris with documented spasm
0.000 0.473 0.526
D37.5 Rectum
0.526 0.474 0.000
C16.5 Lesser curvature of stomach, unspecified
0.521 0.479 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.481 0.519
I31.3 Pericardial effusion (noninflammatory)
0.000 0.482 0.518
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.516 0.483 0.000
C46 Kaposi's sarcoma
0.516 0.483 0.000
I23.8 Other current complications following acute myocardial infarction
0.000 0.486 0.514
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.486 0.514
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
D48.5 Skin
0.513 0.487 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.512 0.487 0.001
C16.9 Stomach, unspecified
0.512 0.488 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.489 0.511
D47.1 Chronic myeloproliferative disease
0.510 0.490 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.508 0.491 0.000
C70 Malignant neoplasm of meninges
0.508 0.491 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.507 0.493 0.000
C34 Malignant neoplasm of bronchus and lung
0.507 0.493 0.000
I05.9 Mitral valve disease, unspecified
0.000 0.493 0.507
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.507 0.493 0.000
C50.8 Overlapping lesion of breast
0.507 0.493 0.000
I27.2 Other secondary pulmonary hypertension
0.000 0.493 0.507
C45 Mesothelioma
0.505 0.494 0.000
Z95.4 Presence of other heart-valve replacement
0.000 0.495 0.505
C16.8 Overlapping lesion of stomach
0.504 0.495 0.000
C16.6 Greater curvature of stomach, unspecified
0.504 0.495 0.000
C16.4 Pylorus
0.504 0.495 0.000
C16.3 Pyloric antrum
0.504 0.495 0.000
C16.2 Body of stomach
0.504 0.495 0.000
C16.1 Fundus of stomach
0.504 0.495 0.000
C65 Malignant neoplasm of renal pelvis
0.504 0.496 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.497 0.503
C17.2 Ileum
0.502 0.498 0.000
I02 Rheumatic chorea
0.000 0.500 0.500
I01 Rheumatic fever with heart involvement
0.000 0.500 0.500
I00 Rheumatic fever without mention of heart involvement
0.000 0.500 0.500
D06.7 Other parts of cervix
0.496 0.504 0.000
D06.1 Exocervix
0.496 0.504 0.000
D06.0 Endocervix
0.496 0.504 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.504 0.495
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.504 0.495
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.504 0.495
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.504 0.495
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.504 0.495
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.504 0.495
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.504 0.495
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.504 0.495
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.504 0.495
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.504 0.495
I68.0 Cerebral amyloid angiopathy
0.000 0.504 0.495
D47.4 Osteomyelofibrosis
0.495 0.505 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.494 0.506 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.494 0.506 0.000
C31 Malignant neoplasm of accessory sinuses
0.494 0.506 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.494 0.506 0.000
C37 Malignant neoplasm of thymus
0.494 0.506 0.000
C33 Malignant neoplasm of trachea
0.494 0.506 0.000
C24.0 Extrahepatic bile duct
0.493 0.507 0.000
C09.8 Overlapping lesion of tonsil
0.493 0.507 0.000
C09.1 Tonsillar pillar (anterior) (posterior)
0.493 0.507 0.000
C09.0 Tonsillar fossa
0.493 0.507 0.000
D37.9 Digestive organ, unspecified
0.492 0.507 0.000
D37.6 Liver, gallbladder and bile ducts
0.492 0.507 0.000
D37.3 Appendix
0.492 0.507 0.000
I49 Other cardiac arrhythmias
0.000 0.508 0.492
C80.0 Malignant neoplasm, primary site unknown, so stated
0.491 0.509 0.000
I73 Other peripheral vascular diseases
0.000 0.511 0.489
C71 Malignant neoplasm of brain
0.489 0.511 0.000
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)
0.489 0.511 0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.489 0.511 0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.489 0.511 0.000
I05.2 Mitral stenosis with insufficiency
0.000 0.511 0.489
D37.1 Stomach
0.488 0.512 0.000
C76.8 Overlapping lesion of other and ill-defined sites
0.488 0.512 0.000
C76.7 Other ill-defined sites
0.488 0.512 0.000
C76.5 Lower limb
0.488 0.512 0.000
C76.4 Upper limb
0.488 0.512 0.000
C76.3 Pelvis
0.488 0.512 0.000
C76.2 Abdomen
0.488 0.512 0.000
C76.1 Thorax
0.488 0.512 0.000
C76.0 Head, face and neck
0.488 0.512 0.000
C32 Malignant neoplasm of larynx
0.487 0.512 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.515 0.485
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.516 0.484
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.516 0.484
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.516 0.484
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.516 0.484
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.516 0.484
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.516 0.484
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.516 0.484
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.516 0.484
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.516 0.484
I40.9 Acute myocarditis, unspecified
0.000 0.516 0.484
I40.8 Other acute myocarditis
0.000 0.516 0.484
I40.1 Isolated myocarditis
0.000 0.516 0.484
I40.0 Infective myocarditis
0.000 0.516 0.484
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.516 0.484
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.516 0.484
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.516 0.484
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.516 0.484
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.516 0.484
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.516 0.484
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.516 0.484
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.516 0.484
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.516 0.484
I48.4 Atypical atrial flutter
0.000 0.516 0.484
I48.3 Typical atrial flutter
0.000 0.516 0.484
I48.2 Chronic atrial fibrillation
0.000 0.516 0.484
I48.1 Persistent atrial fibrillation
0.000 0.516 0.484
I48.0 Paroxysmal atrial fibrillation
0.000 0.516 0.484
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.516 0.484
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.516 0.484
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.516 0.484
I31.8 Other specified diseases of pericardium
0.000 0.518 0.482
I31.2 Haemopericardium, not elsewhere classified
0.000 0.518 0.482
I31.1 Chronic constrictive pericarditis
0.000 0.518 0.482
I31.0 Chronic adhesive pericarditis
0.000 0.518 0.482
I28 Other diseases of pulmonary vessels
0.000 0.519 0.481
C66 Malignant neoplasm of ureter
0.481 0.519 0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.478 0.522 0.000
D48.4 Peritoneum
0.478 0.522 0.000
D48.3 Retroperitoneum
0.478 0.522 0.000
D48.2 Peripheral nerves and autonomic nervous system
0.478 0.522 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.522 0.478
D39.9 Female genital organ, unspecified
0.478 0.522 0.000
D39.7 Other female genital organs
0.478 0.522 0.000
D39.2 Placenta
0.478 0.522 0.000
D39.0 Uterus
0.478 0.522 0.000
C10.8 Overlapping lesion of oropharynx
0.478 0.522 0.000
C10.4 Branchial cleft
0.478 0.522 0.000
C10.3 Posterior wall of oropharynx
0.478 0.522 0.000
C10.2 Lateral wall of oropharynx
0.478 0.522 0.000
C10.1 Anterior surface of epiglottis
0.478 0.522 0.000
C10.0 Vallecula
0.478 0.522 0.000
I42.0 Dilated cardiomyopathy
0.000 0.524 0.476
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.524 0.476
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.524 0.476
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.524 0.476
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.524 0.476
C17.9 Small intestine, unspecified
0.476 0.524 0.000
C17.8 Overlapping lesion of small intestine
0.476 0.524 0.000
C17.3 Meckel's diverticulum
0.476 0.524 0.000
C17.1 Jejunum
0.476 0.524 0.000
C17.0 Duodenum
0.476 0.524 0.000
I05.8 Other mitral valve diseases
0.000 0.524 0.476
I05.1 Rheumatic mitral insufficiency
0.000 0.524 0.476
Z95.3 Presence of xenogenic heart valve
0.000 0.525 0.475
C53.8 Overlapping lesion of cervix uteri
0.474 0.526 0.000
C53.1 Exocervix
0.474 0.526 0.000
C53.0 Endocervix
0.474 0.526 0.000
C80.9 Malignant neoplasm, unspecified
0.473 0.526 0.000
D45 Polycythaemia vera
0.473 0.527 0.000
C24.9 Biliary tract, unspecified
0.472 0.528 0.000
C24.8 Overlapping lesion of biliary tract
0.472 0.528 0.000
C24.1 Ampulla of Vater
0.472 0.528 0.000
I45 Other conduction disorders
0.000 0.528 0.472
C22.1 Intrahepatic bile duct carcinoma
0.471 0.529 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.531 0.469
D48.7 Other specified sites
0.468 0.532 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.468 0.532 0.000
D00.2 Stomach
0.468 0.532 0.000
D00.1 Oesophagus
0.468 0.532 0.000
D00.0 Lip, oral cavity and pharynx
0.468 0.532 0.000
D01.9 Digestive organ, unspecified
0.468 0.532 0.000
D01.7 Other specified digestive organs
0.468 0.532 0.000
D01.5 Liver, gallbladder and bile ducts
0.468 0.532 0.000
D01.4 Other and unspecified parts of intestine
0.468 0.532 0.000
D01.3 Anus and anal canal
0.468 0.532 0.000
D01.2 Rectum
0.468 0.532 0.000
D01.1 Rectosigmoid junction
0.468 0.532 0.000
D01.0 Colon
0.468 0.532 0.000
C25 Malignant neoplasm of pancreas
0.467 0.533 0.000
C60.9 Penis, unspecified
0.465 0.535 0.000
C60.8 Overlapping lesion of penis
0.465 0.535 0.000
C60.2 Body of penis
0.465 0.535 0.000
C60.1 Glans penis
0.465 0.535 0.000
C60.0 Prepuce
0.465 0.535 0.000
C63.9 Male genital organ, unspecified
0.465 0.535 0.000
C63.8 Overlapping lesion of male genital organs
0.465 0.535 0.000
C63.7 Other specified male genital organs
0.465 0.535 0.000
C63.2 Scrotum
0.465 0.535 0.000
C63.1 Spermatic cord
0.465 0.535 0.000
C63.0 Epididymis
0.465 0.535 0.000
D46 Myelodysplastic syndromes
0.465 0.535 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.535 0.464
I22.8 Subsequent myocardial infarction of other sites
0.000 0.537 0.463
D02.4 Respiratory system, unspecified
0.463 0.537 0.000
D02.3 Other parts of respiratory system
0.463 0.537 0.000
D02.2 Bronchus and lung
0.463 0.537 0.000
D02.1 Trachea
0.463 0.537 0.000
C77.5 Intrapelvic lymph nodes
0.462 0.538 0.000
I21.4 Acute subendocardial myocardial infarction
0.000 0.538 0.462
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.539 0.461
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.539 0.461
I06.8 Other rheumatic aortic valve diseases
0.000 0.539 0.461
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.539 0.461
I06.1 Rheumatic aortic insufficiency
0.000 0.539 0.461
I06.0 Rheumatic aortic stenosis
0.000 0.539 0.461
C14.0 Pharynx, unspecified
0.461 0.539 0.000
C22.9 Liver, unspecified
0.459 0.541 0.000
C04.9 Floor of mouth, unspecified
0.457 0.543 0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.457 0.543 0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.457 0.543 0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.457 0.543 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.543 0.457
C68 Malignant neoplasm of other and unspecified urinary organs
0.456 0.543 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.544 0.456
D48.6 Breast
0.456 0.544 0.000
D02.0 Larynx
0.455 0.545 0.000
I35.9 Aortic valve disorder, unspecified
0.000 0.546 0.454
D37.4 Colon
0.453 0.547 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.451 0.548 0.000
C14.8 Overlapping lesion of lip, oral cavity and pharynx
0.450 0.550 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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