TreeWAS – Variant ID: rs12213948

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
K90.0 Coeliac disease	1.000	0.000	0.000
T42.4 Benzodiazepines	0.000	0.455	0.545
K90 Intestinal malabsorption	0.260	0.740	0.000
K90.8 Other intestinal malabsorption	0.195	0.805	0.000
K90.3 Pancreatic steatorrhoea	0.187	0.813	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.187	0.813	0.000
K90.1 Tropical sprue	0.187	0.813	0.000
K90.9 Intestinal malabsorption, unspecified	0.172	0.828	0.000
E10.9 Without complications	0.148	0.852	0.000
E10 Insulin-dependent diabetes mellitus	0.145	0.855	0.000
E10.3 With ophthalmic complications	0.135	0.865	0.000
E10.1 With ketoacidosis	0.134	0.866	0.000
E10.8 With unspecified complications	0.123	0.877	0.000
E10.7 With multiple complications	0.116	0.884	0.000
E10.6 With other specified complications	0.115	0.885	0.000
E10.2 With renal complications	0.113	0.887	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.111	0.889	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.892	0.108
E10.4 With neurological complications	0.107	0.893	0.000
E10.0 With coma	0.105	0.895	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.905	0.095
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.922	0.078
T42.3 Barbiturates	0.000	0.922	0.078
T42.2 Succinimides and oxazolidinediones	0.000	0.922	0.078
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.922	0.078
E10.5 With peripheral circulatory complications	0.076	0.924	0.000
E83 Disorders of mineral metabolism	0.000	0.926	0.074
T42.0 Hydantoin derivatives	0.000	0.940	0.060
T42.1 Iminostilbenes	0.000	0.943	0.057
E83.8 Other disorders of mineral metabolism	0.000	0.946	0.053
E83.2 Disorders of zinc metabolism	0.000	0.946	0.053
E83.0 Disorders of copper metabolism	0.000	0.946	0.053
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.950	0.050
Z95.2 Presence of prosthetic heart valve	0.000	0.950	0.050
E83.3 Disorders of phosphorus metabolism	0.000	0.956	0.044
E10-E14 Diabetes mellitus	0.038	0.962	0.000
E13 Other specified diabetes mellitus	0.032	0.968	0.000
E83.4 Disorders of magnesium metabolism	0.000	0.970	0.030
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.970	0.030
E14 Unspecified diabetes mellitus	0.029	0.971	0.000
E12 Malnutrition-related diabetes mellitus	0.028	0.972	0.000
E13.9 Without complications	0.027	0.973	0.000
E14.4 With neurological complications	0.024	0.976	0.000
E14.5 With peripheral circulatory complications	0.024	0.976	0.000
E13.8 With unspecified complications	0.023	0.977	0.000
E13.7 With multiple complications	0.023	0.977	0.000
E13.6 With other specified complications	0.023	0.977	0.000
E13.5 With peripheral circulatory complications	0.023	0.977	0.000
E13.4 With neurological complications	0.023	0.977	0.000
E13.2 With renal complications	0.023	0.977	0.000
E13.1 With ketoacidosis	0.023	0.977	0.000
E13.0 With coma	0.023	0.977	0.000
E13.3 With ophthalmic complications	0.023	0.977	0.000
E14.1 With ketoacidosis	0.022	0.978	0.000
E14.2 Withrenal complications	0.022	0.978	0.000
E83.5 Disorders of calcium metabolism	0.000	0.979	0.021
D75.1 Secondary polycythaemia	0.000	0.979	0.021
E14.7 With multiple complications	0.021	0.979	0.000
E14.0 With coma	0.021	0.979	0.000
E12.9 Without complications	0.020	0.980	0.000
E12.8 With unspecified complications	0.020	0.980	0.000
E12.7 With multiple complications	0.020	0.980	0.000
E12.6 With other specified complications	0.020	0.980	0.000
E12.5 With peripheral circulatory complications	0.020	0.980	0.000
E12.4 With neurological complications	0.020	0.980	0.000
E12.3 With ophthalmic complications	0.020	0.980	0.000
E12.2 With renal complications	0.020	0.980	0.000
E12.1 With ketoacidosis	0.020	0.980	0.000
E12.0 With coma	0.020	0.980	0.000
E14.9 Without complications	0.019	0.981	0.000
S82.10 Fracture of upper end of tibia (closed)	0.019	0.981	0.000
E14.6 With other specified complications	0.019	0.981	0.000
Z95.3 Presence of xenogenic heart valve	0.000	0.982	0.018
E14.8 With unspecified complications	0.017	0.983	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.984	0.016
Z95.4 Presence of other heart-valve replacement	0.000	0.984	0.016
K90-K93 Other diseases of the digestive system	0.016	0.984	0.000
E14.3 With ophthalmic complications	0.014	0.986	0.000
I69.3 Sequelae of cerebral infarction	0.000	0.988	0.012
K93 Disorders of other digestive organs in diseases classified elsewhere	0.011	0.989	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.011	0.989	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.990	0.010
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.990	0.010
C43.7 Malignant melanoma of lower limb, including hip	0.010	0.990	0.000
D52.9 Folate deficiency anaemia, unspecified	0.000	0.991	0.009
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.008	0.992	0.000
K93.1 Megacolon in Chagas' disease	0.008	0.992	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.008	0.992	0.000
C43 Malignant melanoma of skin	0.007	0.993	0.000
M94.26 Chondromalacia (Lower leg)	0.000	0.993	0.007
C43.1 Malignant melanoma of eyelid, including canthus	0.007	0.993	0.000
Z95.0 Presence of cardiac pacemaker	0.000	0.994	0.006
C43.9 Malignant melanoma of skin, unspecified	0.006	0.994	0.000
S82.1 Fracture of upper end of tibia	0.006	0.994	0.000
C43.8 Overlapping malignant melanoma of skin	0.005	0.994	0.000
C43.0 Malignant melanoma of lip	0.005	0.994	0.000
L85.8 Other specified epidermal thickening	0.000	0.995	0.005
M19.93 Arthrosis, unspecified (Forearm)	0.000	0.995	0.005
C43.2 Malignant melanoma of ear and external auricular canal	0.005	0.995	0.000
M94.2 Chondromalacia	0.000	0.995	0.005
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.000	0.996	0.004
M48.5 Collapsed vertebra, not elsewhere classified	0.004	0.996	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.004	0.996	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.004	0.996	0.000
E11.2 With renal complications	0.000	0.996	0.004
C81.9 Hodgkin's disease, unspecified	0.000	0.996	0.004
S00.8 Superficial injury of other parts of head	0.000	0.996	0.004
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
D52 Folate deficiency anaemia	0.000	0.996	0.004
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.996	0.004
S00.0 Superficial injury of scalp	0.000	0.996	0.004
H11.9 Disorder of conjunctiva, unspecified	0.000	0.996	0.004
V23.4 Driver injured in traffic accident	0.004	0.996	0.000
L90.0 Lichen sclerosus et atrophicus	0.000	0.996	0.004
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.004	0.996	0.000
K26.3 Acute without haemorrhage or perforation	0.004	0.996	0.000
S00.9 Superficial injury of head, part unspecified	0.000	0.996	0.004
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.996	0.004
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.996	0.004
M94.29 Chondromalacia (Site unspecified)	0.000	0.996	0.003
M94.28 Chondromalacia (Other)	0.000	0.996	0.003
M94.27 Chondromalacia (Ankle and foot)	0.000	0.996	0.003
M94.25 Chondromalacia (Pelvic region and thigh)	0.000	0.996	0.003
M94.24 Chondromalacia (Hand)	0.000	0.996	0.003
M94.23 Chondromalacia (Forearm)	0.000	0.996	0.003
M94.22 Chondromalacia (Upper arm)	0.000	0.996	0.003
M94.21 Chondromalacia (Shoulder region)	0.000	0.996	0.003
M94.20 Chondromalacia (Multiple sites)	0.000	0.996	0.003
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.003	0.996	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.004	0.996	0.000
S00 Superficial injury of head	0.000	0.997	0.003
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.003	0.997	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.003	0.997	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.003	0.997	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.003	0.997	0.000
H50.1 Divergent concomitant strabismus	0.000	0.997	0.003
S82.11 Fracture of upper end of tibia (open)	0.003	0.997	0.000
D52.8 Other folate deficiency anaemias	0.000	0.997	0.003
D52.1 Drug-induced folate deficiency anaemia	0.000	0.997	0.003
D52.0 Dietary folate deficiency anaemia	0.000	0.997	0.003
L85 Other epidermal thickening	0.000	0.997	0.003
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.997	0.003
C43.4 Malignant melanoma of scalp and neck	0.003	0.997	0.000
N90.5 Atrophy of vulva	0.003	0.997	0.000
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris	0.000	0.997	0.003
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.997	0.003
C43.3 Malignant melanoma of other and unspecified parts of face	0.003	0.997	0.000
D48.7 Other specified sites	0.000	0.997	0.003
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.003	0.997	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.003	0.997	0.000
S91.3 Open wound of other parts of foot	0.000	0.997	0.003
I69 Sequelae of cerebrovascular disease	0.000	0.997	0.003
S00.3 Superficial injury of nose	0.000	0.997	0.003
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.997	0.003
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.997	0.003
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.997	0.003
S00.2 Other superficial injuries of eyelid and periocular area	0.000	0.997	0.003
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.997	0.003
D48.6 Breast	0.000	0.997	0.003
D48.1 Connective and other soft tissue	0.000	0.997	0.003
Z40 Prophylactic surgery	0.000	0.997	0.003
C64 Malignant neoplasm of kidney, except renal pelvis	0.000	0.997	0.003
L85.9 Epidermal thickening, unspecified	0.000	0.997	0.003
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.997	0.003
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.000	0.997	0.003
D50.9 Iron deficiency anaemia, unspecified	0.003	0.997	0.000
L85.3 Xerosis cutis	0.000	0.997	0.003
L85.2 Keratosis punctata (palmaris et plantaris)	0.000	0.997	0.003
L85.0 Acquired ichthyosis	0.000	0.997	0.003
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.997	0.002
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.997	0.002
D48.4 Peritoneum	0.000	0.997	0.003
D48.2 Peripheral nerves and autonomic nervous system	0.000	0.997	0.003
S62.20 Fracture of first metacarpal bone (closed)	0.003	0.997	0.000
S00.7 Multiple superficial injuries of head	0.000	0.997	0.003
M94 Other disorders of cartilage	0.000	0.997	0.003
S00.4 Superficial injury of ear	0.000	0.997	0.002
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.997	0.002
D72.8 Other specified disorders of white blood cells	0.003	0.997	0.000
M62.88 Other specified disorders of muscle (Other)	0.000	0.997	0.002
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.000	0.997	0.002
B44.9 Aspergillosis, unspecified	0.002	0.998	0.000
N42.8 Other specified disorders of prostate	0.000	0.998	0.002
D64.9 Anaemia, unspecified	0.002	0.998	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.002	0.998	0.000
D48.3 Retroperitoneum	0.000	0.998	0.002
M94.8 Other specified disorders of cartilage	0.000	0.998	0.002
M94.88 Other specified disorders of cartilage (Other)	0.000	0.998	0.002
Z40.9 Prophylactic surgery, unspecified	0.000	0.998	0.002
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.998	0.002
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.000	0.998	0.002
A63.0 Anogenital (venereal) warts	0.000	0.998	0.002
K07.1 Anomalies of jaw-cranial base relationship	0.000	0.998	0.002
Z76.9 Persons encountering health services in unspecified circumstances	0.002	0.998	0.000
S00.5 Superficial injury of lip and oral cavity	0.000	0.998	0.002
Z03.2 Observation for suspected mental and behavioural disorders	0.000	0.998	0.002
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.002	0.998	0.000
D48.0 Bone and articular cartilage	0.000	0.998	0.002
D75 Other diseases of blood and blood-forming organs	0.000	0.998	0.002
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.998	0.002
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.002	0.998	0.000
C82.2 Large cell, follicular	0.002	0.998	0.000
M94.3 Chondrolysis	0.000	0.998	0.002
M94.1 Relapsing polychondritis	0.000	0.998	0.002
S91 Open wound of ankle and foot	0.000	0.998	0.002
D37.4 Colon	0.000	0.998	0.002
M48.9 Spondylopathy, unspecified	0.002	0.998	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.998	0.002
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.002	0.998	0.000
M48.96 Spondylopathy, unspecified (Lumbar region)	0.002	0.998	0.000
K26.7 Chronic without haemorrhage or perforation	0.002	0.998	0.000
N02.8 Other	0.000	0.998	0.002
K63.3 Ulcer of intestine	0.000	0.998	0.002
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.998	0.002
M48 Other spondylopathies	0.002	0.998	0.000
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.000	0.998	0.002
M94.84 Other specified disorders of cartilage (Hand)	0.000	0.998	0.002
M94.83 Other specified disorders of cartilage (Forearm)	0.000	0.998	0.002
M94.82 Other specified disorders of cartilage (Upper arm)	0.000	0.998	0.002
M94.81 Other specified disorders of cartilage (Shoulder region)	0.000	0.998	0.002
M94.80 Other specified disorders of cartilage (Multiple sites)	0.000	0.998	0.002
S91.0 Open wound of ankle	0.000	0.998	0.002
M48.92 Spondylopathy, unspecified (Cervical region)	0.002	0.998	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.000	0.998	0.002
S00.1 Contusion of eyelid and periocular area	0.000	0.998	0.002
M48.8 Other specified spondylopathies	0.002	0.998	0.000
M94.0 Chondrocostal junction syndrome [Tietze]	0.000	0.998	0.002
C82.0 Small cleaved cell, follicular	0.002	0.998	0.000
M48.86 Other specified spondylopathies (Lumbar region)	0.002	0.998	0.000
C82.4 Follicular lymphoma grade IIIb	0.002	0.998	0.000
D48.5 Skin	0.000	0.998	0.002
M80.9 Unspecified osteoporosis with pathological fracture	0.002	0.998	0.000
M94.9 Disorder of cartilage, unspecified	0.000	0.998	0.002
Z83.5 Family history of eye and ear disorders	0.000	0.998	0.002
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.000	0.998	0.002
C45.9 Mesothelioma, unspecified	0.002	0.998	0.000
C82.6 Cutaneous follicle centre lymphoma	0.002	0.998	0.000
C82.5 Diffuse follicle centre lymphoma	0.002	0.998	0.000
G95.2 Cord compression, unspecified	0.000	0.998	0.002
M20.3 Other deformity of hallux (acquired)	0.002	0.998	0.000
M48.99 Spondylopathy, unspecified (Site unspecified)	0.002	0.998	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.002	0.998	0.000
I30.9 Acute pericarditis, unspecified	0.002	0.998	0.000
M34.9 Systemic sclerosis, unspecified	0.002	0.998	0.000
M47.2 Other spondylosis with radiculopathy	0.002	0.998	0.000
N42.0 Calculus of prostate	0.000	0.998	0.002
S91.2 Open wound of toe(s) with damage to nail	0.000	0.998	0.002
M13.00 Polyarthritis, unspecified (Multiple sites)	0.002	0.998	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.002	0.998	0.000
C22.0 Liver cell carcinoma	0.000	0.998	0.002
C82.1 Mixed small cleaved and large cell, follicular	0.002	0.998	0.000
I63.9 Cerebral infarction, unspecified	0.000	0.998	0.002
K05.3 Chronic periodontitis	0.002	0.998	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.002	0.998	0.000
M25.53 Pain in joint (Forearm)	0.000	0.998	0.002
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.002	0.998	0.000
M94.19 Relapsing polychondritis (Site unspecified)	0.000	0.998	0.002
M94.18 Relapsing polychondritis (Other)	0.000	0.998	0.002
M94.17 Relapsing polychondritis (Ankle and foot)	0.000	0.998	0.002
M94.16 Relapsing polychondritis (Lower leg)	0.000	0.998	0.002
M94.15 Relapsing polychondritis (Pelvic region and thigh)	0.000	0.998	0.002
M94.14 Relapsing polychondritis (Hand)	0.000	0.998	0.002
M94.13 Relapsing polychondritis (Forearm)	0.000	0.998	0.002
M94.12 Relapsing polychondritis (Upper arm)	0.000	0.998	0.002
M94.11 Relapsing polychondritis (Shoulder region)	0.000	0.998	0.002
M94.10 Relapsing polychondritis (Multiple sites)	0.000	0.998	0.002
M94.39 Chondrolysis (Site unspecified)	0.000	0.998	0.002
M94.38 Chondrolysis (Other)	0.000	0.998	0.002
M94.37 Chondrolysis (Ankle and foot)	0.000	0.998	0.002
M94.36 Chondrolysis (Lower leg)	0.000	0.998	0.002
M94.35 Chondrolysis (Pelvic region and thigh)	0.000	0.998	0.002
M94.34 Chondrolysis (Hand)	0.000	0.998	0.002
M94.33 Chondrolysis (Forearm)	0.000	0.998	0.002
M94.32 Chondrolysis (Upper arm)	0.000	0.998	0.002
M94.31 Chondrolysis (Shoulder region)	0.000	0.998	0.002
M94.30 Chondrolysis (Multiple sites)	0.000	0.998	0.002
M14.2 Diabetic arthropathy	0.002	0.998	0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.002	0.998	0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.002	0.998	0.000
M48.94 Spondylopathy, unspecified (Thoracic region)	0.002	0.998	0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.002	0.998	0.000
N60.1 Diffuse cystic mastopathy	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.000	0.998	0.002
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.998	0.002
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.002	0.998	0.000
T40.6 Other and unspecified narcotics	0.000	0.998	0.002
V23.9 Unspecified motorcycle rider injured in traffic accident	0.002	0.998	0.000
V23.3 Person injured while boarding or alighting	0.002	0.998	0.000
V23.2 Unspecified motorcycle rider injured in nontraffic accident	0.002	0.998	0.000
V23.1 Passenger injured in nontraffic accident	0.002	0.998	0.000
V23.0 Driver injured in nontraffic accident	0.002	0.998	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.998	0.002
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.998	0.002
M54.39 Sciatica (Site unspecified)	0.000	0.998	0.002
S82.31 Fracture of lower end of tibia (open)	0.002	0.998	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.998	0.002
S91.1 Open wound of toe(s) without damage to nail	0.000	0.998	0.002
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.998	0.002
S99.9 Unspecified injury of ankle and foot	0.000	0.998	0.002
T45.0 Antiallergic and antiemetic drugs	0.000	0.998	0.002
C81 Hodgkin's disease	0.000	0.998	0.002
D72 Other disorders of white blood cells	0.002	0.998	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.002	0.998	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.002	0.998	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.998	0.002
G50.0 Trigeminal neuralgia	0.002	0.998	0.000
M48.4 Fatigue fracture of vertebra	0.002	0.998	0.000
M48.3 Traumatic spondylopathy	0.002	0.998	0.000
M48.2 Kissing spine	0.002	0.998	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.002	0.998	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.000	0.998	0.002
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
S72.20 Subtrochanteric fracture (closed)	0.000	0.998	0.002
C82.3 Follicular lymphoma grade IIIa	0.002	0.998	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.998	0.002
M48.89 Other specified spondylopathies (Site unspecified)	0.001	0.998	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.001	0.998	0.000
M48.84 Other specified spondylopathies (Thoracic region)	0.001	0.998	0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.001	0.998	0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.001	0.998	0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.001	0.998	0.000
M94.07 Chondrocostal junction syndrome [Tietze]-Ankle/foot	0.000	0.998	0.001
M94.06 Chondrocostal junction syndrome [Tietze]-Lower leg	0.000	0.998	0.001
M94.05 Chondrocostal junction syndrome [Tietze]-Pelvic/thigh	0.000	0.998	0.001
M94.04 Chondrocostal junction syndrome [Tietze]-Hand	0.000	0.998	0.001
M94.03 Chondrocostal junction syndrome [Tietze]-Forearm	0.000	0.998	0.001
M94.02 Chondrocostal junction syndrome [Tietze]-Upper arm	0.000	0.998	0.001
M94.01 Chondrocostal junction syndrome [Tietze]-Shldr region	0.000	0.998	0.001
M94.00 Chondrocostal junction syndrome [Tietze]-Mult sites	0.000	0.998	0.001
R52.9 Pain, unspecified	0.000	0.998	0.002
T50.8 Diagnostic agents	0.000	0.998	0.002
D72.1 Eosinophilia	0.002	0.998	0.000
D75.0 Familial erythrocytosis	0.000	0.998	0.001
M34.1 CR(E)ST syndrome	0.002	0.998	0.000
M25.74 Osteophyte (Hand)	0.002	0.998	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.001	0.998	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.001	0.998	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.001	0.998	0.000
M94.99 Disorder of cartilage, unspecified (Site unspecified)	0.000	0.998	0.001
M94.98 Disorder of cartilage, unspecified (Other)	0.000	0.998	0.001
M94.97 Disorder of cartilage, unspecified (Ankle and foot)	0.000	0.998	0.001
M94.95 Disorder of cartilage, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
M94.94 Disorder of cartilage, unspecified (Hand)	0.000	0.998	0.001
M94.93 Disorder of cartilage, unspecified (Forearm)	0.000	0.998	0.001
M94.92 Disorder of cartilage, unspecified (Upper arm)	0.000	0.998	0.001
M94.91 Disorder of cartilage, unspecified (Shoulder region)	0.000	0.998	0.001
M94.90 Disorder of cartilage, unspecified (Multiple sites)	0.000	0.998	0.001
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.002	0.998	0.000
V23.5 Passenger injured in traffic accident	0.001	0.998	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.998	0.002
M24.54 Contracture of joint (Hand)	0.000	0.998	0.002
E27.1 Primary adrenocortical insufficiency	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.000	0.998	0.002
M94.08 Chondrocostal junction syndrome [Tietze]-Other	0.000	0.998	0.001
S96.8 Injury of other muscles and tendons at ankle and foot level	0.000	0.998	0.002
T50.4 Drugs affecting uric acid metabolism	0.000	0.998	0.001
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.001	0.998	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.001	0.998	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.001	0.998	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.001	0.998	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.001	0.998	0.000
M94.89 Other specified disorders of cartilage (Site unspecified)	0.000	0.998	0.001
Z31.2 In vitro fertilisation	0.000	0.998	0.002
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.000	0.998	0.002
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.001
C81.0 Lymphocytic predominance	0.000	0.998	0.001
D37.1 Stomach	0.000	0.998	0.002
K35.1 Acute appendicitis with peritoneal abscess	0.002	0.998	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.002	0.998	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.002	0.998	0.000
V23.99 Motorcycle rider injured in collision with car, pick-up truck or van, Unspecified motorcycle rider injured in traffic accident, Unspecified place	0.001	0.998	0.000
C81.2 Mixed cellularity	0.000	0.998	0.001
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.998	0.001
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.998	0.001
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
M94.09 Chondrocostal junction syndrome [Tietze]-Site unspec	0.000	0.998	0.001
O75.8 Other specified complications of labour and delivery	0.000	0.998	0.002
H11.2 Conjunctival scars	0.000	0.998	0.001
O03.4 Incomplete, without complication	0.000	0.998	0.002
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.998	0.001
T45.8 Other primarily systemic and haematological agents	0.000	0.998	0.001
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.998	0.001
T45.6 Fibrinolysis-affecting drugs	0.000	0.998	0.001
T45.4 Iron and its compounds	0.000	0.998	0.001
T45.3 Enzymes, not elsewhere classified	0.000	0.998	0.001
T45.2 Vitamins, not elsewhere classified	0.000	0.998	0.001
Z04.1 Examination and observation following transport accident	0.002	0.998	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.001	0.998	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.000	0.998	0.001
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.998	0.001
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.000	0.998	0.001
C81.3 Lymphocytic depletion	0.000	0.998	0.001
D72.9 Disorder of white blood cells, unspecified	0.001	0.998	0.000
D72.0 Genetic anomalies of leukocytes	0.001	0.998	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.998	0.001
Z40.8 Other prophylactic surgery	0.000	0.998	0.001
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.000	0.999	0.001
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.001	0.999	0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.001	0.999	0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.001	0.999	0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.001	0.999	0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.001	0.999	0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.001	0.999	0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.001	0.999	0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.001	0.999	0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.001	0.999	0.000
M48.29 Kissing spine (Site unspecified)	0.001	0.999	0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M48.27 Kissing spine (Lumbosacral region)	0.001	0.999	0.000
M48.26 Kissing spine (Lumbar region)	0.001	0.999	0.000
M48.25 Kissing spine (Thoracolumbar region)	0.001	0.999	0.000
M48.24 Kissing spine (Thoracic region)	0.001	0.999	0.000
M48.23 Kissing spine (Cervicothoracic region)	0.001	0.999	0.000
M48.22 Kissing spine (Cervical region)	0.001	0.999	0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.001	0.999	0.000
M48.20 Kissing spine (Multiple sites in spine)	0.001	0.999	0.000
M48.39 Traumatic spondylopathy (Site unspecified)	0.001	0.999	0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.001	0.999	0.000
M48.36 Traumatic spondylopathy (Lumbar region)	0.001	0.999	0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.001	0.999	0.000
M48.34 Traumatic spondylopathy (Thoracic region)	0.001	0.999	0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.001	0.999	0.000
M48.32 Traumatic spondylopathy (Cervical region)	0.001	0.999	0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.001	0.999	0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.001	0.999	0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.001	0.999	0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.001	0.999	0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.001	0.999	0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.001	0.999	0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.001	0.999	0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.001	0.999	0.000
M48.42 Fatigue fracture of vertebra (Cervical region)	0.001	0.999	0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.001	0.999	0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.001	0.999	0.000
C81.7 Other Hodgkin's disease	0.000	0.999	0.001
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.999	0.001
T36.0 Penicillins	0.000	0.999	0.001
T50.7 Analeptics and opioid receptor antagonists	0.000	0.999	0.001
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.999	0.001
T50.5 Appetite depressants	0.000	0.999	0.001
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.999	0.001
T50.1 Loop [high-ceiling] diuretics	0.000	0.999	0.001
T50.0 Mineralocorticoids and their antagonists	0.000	0.999	0.001
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.999	0.001
A63.8 Other specified predominantly sexually transmitted diseases	0.000	0.999	0.001
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.999	0.001
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.999	0.001
M12.30 Palindromic rheumatism (Multiple sites)	0.001	0.999	0.000
V17.4 Driver injured in traffic accident	0.000	0.999	0.001
G37.5 Concentric sclerosis [Balo]	0.000	0.999	0.001
G37.4 Subacute necrotising myelitis	0.000	0.999	0.001
G37.2 Central pontine myelinolysis	0.000	0.999	0.001
G37.1 Central demyelination of corpus callosum	0.000	0.999	0.001
G37.0 Diffuse sclerosis	0.000	0.999	0.001
M34.8 Other forms of systemic sclerosis	0.001	0.999	0.000
T36.9 Systemic antibiotic, unspecified	0.000	0.999	0.001
T36.8 Other systemic antibiotics	0.000	0.999	0.001
T36.7 Antifungal antibiotics, systemically used	0.000	0.999	0.001
T36.6 Rifamycins	0.000	0.999	0.001
T36.5 Aminoglycosides	0.000	0.999	0.001
T36.4 Tetracyclines	0.000	0.999	0.001
T36.3 Macrolides	0.000	0.999	0.001
T36.2 Chloramphenicol group	0.000	0.999	0.001
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.999	0.001
T45.5 Anticoagulants	0.000	0.999	0.001
Z31.4 Procreative investigation and testing	0.000	0.999	0.001
H11 Other disorders of conjunctiva	0.000	0.999	0.001
M11.26 Other chondrocalcinosis (Lower leg)	0.001	0.999	0.000
K07.0 Major anomalies of jaw size	0.000	0.999	0.001
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.999	0.001
Z95.1 Presence of aortocoronary bypass graft	0.000	0.999	0.001
C45.0 Mesothelioma of pleura	0.001	0.999	0.000
D58.0 Hereditary spherocytosis	0.001	0.999	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.999	0.001
K07.2 Anomalies of dental arch relationship	0.000	0.999	0.001
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.999	0.001
T48.5 Anti-common-cold drugs	0.000	0.999	0.001
T48.4 Expectorants	0.000	0.999	0.001
T48.3 Antitussives	0.000	0.999	0.001
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.999	0.001
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.999	0.001
T48.0 Oxytocic drugs	0.000	0.999	0.001
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.001	0.999	0.000
D37.2 Small intestine	0.000	0.999	0.001
O04.9 Complete or unspecified, without complication	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations