TreeWAS – Variant ID: rs12220488

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D24 Benign neoplasm of breast	0.999	0.001	0.000
N61 Inflammatory disorders of breast	0.031	0.969	0.000
N60.3 Fibrosclerosis of breast	0.027	0.973	0.000
N60.1 Diffuse cystic mastopathy	0.026	0.974	0.000
H60.9 Otitis externa, unspecified	0.026	0.974	0.000
N60 Benign mammary dysplasia	0.025	0.975	0.000
H60.1 Cellulitis of external ear	0.024	0.976	0.000
H60 Otitis externa	0.023	0.977	0.000
N60-N64 Disorders of breast	0.023	0.977	0.000
N63 Unspecified lump in breast	0.021	0.979	0.000
H60.4 Cholesteatoma of external ear	0.021	0.979	0.000
N60.9 Benign mammary dysplasia, unspecified	0.020	0.980	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.020	0.980	0.000
H60.5 Acute otitis externa, non-infective	0.019	0.981	0.000
K63.9 Disease of intestine, unspecified	0.000	0.982	0.018
N60.2 Fibroadenosis of breast	0.018	0.982	0.000
H60.3 Other infective otitis externa	0.017	0.982	0.000
H60.0 Abscess of external ear	0.017	0.983	0.000
Z80.3 Family history of malignant neoplasm of breast	0.015	0.985	0.000
H60.2 Malignant otitis externa	0.015	0.985	0.000
H60.8 Other otitis externa	0.014	0.986	0.000
T43.2 Other and unspecified antidepressants	0.011	0.989	0.000
Z42.1 Follow-up care involving plastic surgery of breast	0.011	0.989	0.000
N64 Other disorders of breast	0.010	0.990	0.000
D04.6 Skin of upper limb, including shoulder	0.010	0.990	0.000
Z92.3 Personal history of irradiation	0.010	0.990	0.000
N60.0 Solitary cyst of breast	0.010	0.990	0.000
I34.0 Mitral (valve) insufficiency	0.000	0.990	0.010
N64.1 Fat necrosis of breast	0.009	0.991	0.000
K29.0 Acute haemorrhagic gastritis	0.009	0.991	0.000
N60.8 Other benign mammary dysplasias	0.008	0.992	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.008	0.992	0.000
N64.3 Galactorrhoea not associated with childbirth	0.008	0.992	0.000
N64.5 Other signs and symptoms in breast	0.008	0.992	0.000
N64.0 Fissure and fistula of nipple	0.008	0.992	0.000
N64.2 Atrophy of breast	0.007	0.993	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.993	0.007
C77.3 Axillary and upper limb lymph nodes	0.007	0.993	0.000
I34 Nonrheumatic mitral valve disorders	0.000	0.993	0.007
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.007	0.993	0.000
D05 Carcinoma in situ of breast	0.007	0.993	0.000
N64.4 Mastodynia	0.007	0.993	0.000
Z85.3 Personal history of malignant neoplasm of breast	0.006	0.994	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.006	0.994	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.000	0.994	0.006
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.994	0.006
H60-H62 Diseases of external ear	0.005	0.995	0.000
T43.6 Psychostimulants with abuse potential	0.005	0.995	0.000
N64.9 Disorder of breast, unspecified	0.005	0.995	0.000
H47.3 Other disorders of optic disk	0.005	0.995	0.000
T43.9 Psychotropic drug, unspecified	0.005	0.995	0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.000	0.995	0.005
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.995	0.005
T43.3 Phenothiazine antipsychotics and neuroleptics	0.005	0.995	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.005	0.995	0.000
O61.0 Failed medical induction of labour	0.005	0.995	0.000
I34.1 Mitral (valve) prolapse	0.000	0.995	0.005
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.005	0.995	0.000
D05.0 Lobular carcinoma in situ	0.005	0.995	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
N60.4 Mammary duct ectasia	0.004	0.995	0.000
M79.67 Pain in limb (Ankle and foot)	0.004	0.996	0.000
D05.7 Other carcinoma in situ of breast	0.004	0.996	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.004	0.996	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.004	0.996	0.000
M17.3 Other posttraumatic gonarthrosis	0.000	0.996	0.004
H47.2 Optic atrophy	0.004	0.996	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.004	0.996	0.000
D05.1 Intraductal carcinoma in situ	0.004	0.996	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.004	0.996	0.000
G30.9 Alzheimer's disease, unspecified	0.004	0.996	0.000
F01.9 Vascular dementia, unspecified	0.004	0.996	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.996	0.004
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.004	0.996	0.000
N03.9 Unspecified	0.000	0.996	0.004
D04 Carcinoma in situ of skin	0.004	0.996	0.000
N64.8 Other specified disorders of breast	0.004	0.996	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.003	0.996	0.000
I27.2 Other secondary pulmonary hypertension	0.000	0.997	0.003
M89.86 Other specified disorders of bone (Lower leg)	0.003	0.997	0.000
D00-D09 In situ neoplasms	0.003	0.997	0.000
J02.9 Acute pharyngitis, unspecified	0.003	0.997	0.000
H47.7 Disorder of visual pathways, unspecified	0.003	0.997	0.000
H47.6 Disorders of visual cortex	0.003	0.997	0.000
H47.5 Disorders of other visual pathways	0.003	0.997	0.000
H47.4 Disorders of optic chiasm	0.003	0.997	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.003	0.997	0.000
H47.1 Papilloedema, unspecified	0.003	0.997	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.003	0.997	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.003	0.997	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
H62.2 Otitis externa in mycoses	0.003	0.997	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.003	0.997	0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.003	0.997	0.000
I05.0 Mitral stenosis	0.000	0.997	0.003
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.003	0.997	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.003	0.997	0.000
M89.8 Other specified disorders of bone	0.003	0.997	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.003	0.997	0.000
D04.1 Skin of eyelid, including canthus	0.003	0.997	0.000
D04.9 Skin, unspecified	0.003	0.997	0.000
D04.8 Skin of other sites	0.003	0.997	0.000
D04.0 Skin of lip	0.003	0.997	0.000
I05 Rheumatic mitral valve diseases	0.000	0.997	0.003
R49.0 Dysphonia	0.003	0.997	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.003	0.997	0.000
Z92.0 Personal history of contraception	0.003	0.997	0.000
S82.60 Fracture of lateral malleolus (closed)	0.003	0.997	0.000
D43.2 Brain, unspecified	0.003	0.997	0.000
K70.9 Alcoholic liver disease, unspecified	0.000	0.997	0.003
D02 Carcinoma in situ of middle ear and respiratory system	0.003	0.997	0.000
N03 Chronic nephritic syndrome	0.000	0.997	0.003
N03.1 Focal and segmental glomerular lesions	0.000	0.997	0.003
K57.1 Diverticular disease of small intestine without perforation or abscess	0.003	0.997	0.000
M21.0 Valgus deformity, not elsewhere classified	0.003	0.997	0.000
D04.2 Skin of ear and external auricular canal	0.003	0.997	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.003	0.997	0.000
M89.84 Other specified disorders of bone (Hand)	0.003	0.997	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.003	0.997	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
F01 Vascular dementia	0.003	0.997	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.003	0.997	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.003	0.997	0.000
O61 Failed induction of labour	0.003	0.997	0.000
D03 Melanoma in situ	0.003	0.997	0.000
I27.0 Primary pulmonary hypertension	0.000	0.997	0.003
D01 Carcinoma in situ of other and unspecified digestive organs	0.002	0.997	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.003	0.997	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.002	0.997	0.000
O61.1 Failed instrumental induction of labour	0.002	0.997	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.003	0.997	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.997	0.003
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.002	0.997	0.000
D07.0 Endometrium	0.002	0.997	0.000
K70.1 Alcoholic hepatitis	0.000	0.997	0.002
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.000	0.998	0.002
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.002	0.998	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.002	0.998	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.002	0.998	0.000
D04.4 Skin of scalp and neck	0.002	0.998	0.000
I05.2 Mitral stenosis with insufficiency	0.000	0.998	0.002
I89.0 Lymphoedema, not elsewhere classified	0.002	0.998	0.000
E65 Localised adiposity	0.002	0.998	0.000
D02.0 Larynx	0.002	0.998	0.000
D04.3 Skin of other and unspecified parts of face	0.002	0.998	0.000
N03.8 Other	0.000	0.998	0.002
D07.4 Penis	0.002	0.998	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.998	0.002
M89.83 Other specified disorders of bone (Forearm)	0.002	0.998	0.000
C60.9 Penis, unspecified	0.002	0.998	0.000
D02.2 Bronchus and lung	0.002	0.998	0.000
H46 Optic neuritis	0.002	0.998	0.000
D02.4 Respiratory system, unspecified	0.002	0.998	0.000
D02.3 Other parts of respiratory system	0.002	0.998	0.000
D02.1 Trachea	0.002	0.998	0.000
N03.7 Diffuse crescentic glomerulonephritis	0.000	0.998	0.002
N03.6 Dense deposit disease	0.000	0.998	0.002
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.998	0.002
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.998	0.002
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.998	0.002
N03.2 Diffuse membranous glomerulonephritis	0.000	0.998	0.002
N03.0 Minor glomerular abnormality	0.000	0.998	0.002
D03.2 Melanoma in situ of ear and external auricular canal	0.002	0.998	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.002	0.998	0.000
D00.1 Oesophagus	0.002	0.998	0.000
D09 Carcinoma in situ of other and unspecified sites	0.002	0.998	0.000
I27 Other pulmonary heart diseases	0.000	0.998	0.002
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.002	0.998	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.002	0.998	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.002	0.998	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
D01.5 Liver, gallbladder and bile ducts	0.002	0.998	0.000
F02.3 Dementia in Parkinson's disease	0.002	0.998	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.002	0.998	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.002	0.998	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.002	0.998	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.002	0.998	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.002	0.998	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.002	0.998	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.002	0.998	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.002	0.998	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.002	0.998	0.000
I05.8 Other mitral valve diseases	0.000	0.998	0.002
I05.1 Rheumatic mitral insufficiency	0.000	0.998	0.002
W03.9 Unspecified place	0.002	0.998	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.002	0.998	0.000
D07.6 Other and unspecified male genital organs	0.002	0.998	0.000
D07.3 Other and unspecified female genital organs	0.002	0.998	0.000
M89.88 Other specified disorders of bone (Other)	0.002	0.998	0.000
F01.8 Other vascular dementia	0.002	0.998	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.002	0.998	0.000
F01.2 Subcortical vascular dementia	0.002	0.998	0.000
F01.0 Vascular dementia of acute onset	0.002	0.998	0.000
D00.2 Stomach	0.002	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
K70 Alcoholic liver disease	0.000	0.998	0.002
D01.0 Colon	0.002	0.998	0.000
O61.8 Other failed induction of labour	0.002	0.998	0.000
D03.9 Melanoma in situ, unspecified	0.002	0.998	0.000
D01.9 Digestive organ, unspecified	0.002	0.998	0.000
D01.7 Other specified digestive organs	0.002	0.998	0.000
D01.4 Other and unspecified parts of intestine	0.002	0.998	0.000
D01.1 Rectosigmoid junction	0.002	0.998	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.002	0.998	0.000
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.002	0.998	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.002	0.998	0.000
D03.0 Melanoma in situ of lip	0.002	0.998	0.000
I71.0 Dissection of aorta [any part]	0.000	0.998	0.002
Z36.8 Other antenatal screening	0.002	0.998	0.000
F02 Dementia in other diseases classified elsewhere	0.002	0.998	0.000
D03.4 Melanoma in situ of scalp and neck	0.002	0.998	0.000
D04.5 Skin of trunk	0.002	0.998	0.000
D07.2 Vagina	0.002	0.998	0.000
Z80.8 Family history of malignant neoplasm of other organs or systems	0.002	0.998	0.000
O61.9 Failed induction of labour, unspecified	0.002	0.998	0.000
M21 Other acquired deformities of limbs	0.002	0.998	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.000	0.998	0.002
D01.2 Rectum	0.002	0.998	0.000
D03.8 Melanoma in situ of other sites	0.002	0.998	0.000
K70.0 Alcoholic fatty liver	0.000	0.998	0.002
S62.30 Fracture of other metacarpal bone (closed)	0.002	0.998	0.000
M21.3 Wrist or foot drop (acquired)	0.002	0.998	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.002	0.998	0.000
F01.1 Multi-infarct dementia	0.002	0.998	0.000
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.002	0.998	0.000
H48.0 Optic atrophy in diseases classified elsewhere	0.002	0.998	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.002	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.002	0.998	0.000
Y43.1 Antineoplastic antimetabolites	0.000	0.998	0.002
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.002	0.998	0.000
D09.3 Thyroid and other endocrine glands	0.002	0.998	0.000
D09.2 Eye	0.002	0.998	0.000
I27.1 Kyphoscoliotic heart disease	0.000	0.998	0.002
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.000	0.998	0.002
D07.1 Vulva	0.002	0.998	0.000
H11.8 Other specified disorders of conjunctiva	0.000	0.998	0.002
J18.0 Bronchopneumonia, unspecified	0.002	0.998	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.998	0.002
M21.8 Other specified acquired deformities of limbs	0.002	0.998	0.000
D09.7 Carcinoma in situ of other specified sites	0.002	0.998	0.000
F02.0 Dementia in Pick's disease	0.002	0.998	0.000
O30.0 Twin pregnancy	0.002	0.998	0.000
M54.16 Radiculopathy (Lumbar region)	0.000	0.998	0.002
C15.5 Lower third of oesophagus	0.002	0.998	0.000
D00.0 Lip, oral cavity and pharynx	0.002	0.998	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.002	0.998	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.002	0.998	0.000
C77.0 Lymph nodes of head, face and neck	0.002	0.998	0.000
D01.3 Anus and anal canal	0.002	0.998	0.000
N73.6 Female pelvic peritoneal adhesions	0.002	0.998	0.000
D06 Carcinoma in situ of cervix uteri	0.002	0.998	0.000
F07.2 Postconcussional syndrome	0.002	0.998	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.002	0.998	0.000
G30 Alzheimer's disease	0.002	0.998	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.002	0.998	0.000
D32.9 Meninges, unspecified	0.000	0.998	0.002
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.002	0.998	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
D09.9 Carcinoma in situ, unspecified	0.002	0.998	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.002	0.998	0.000
F02.2 Dementia in Huntington's disease	0.002	0.998	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.002	0.998	0.000
M89 Other disorders of bone	0.002	0.998	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.002	0.998	0.000
B18.2 Chronic viral hepatitis C	0.000	0.998	0.002
D07.5 Prostate	0.002	0.998	0.000
Z63.7 Other stressful life events affecting family and household	0.000	0.998	0.002
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.000	0.998	0.002
F05.1 Delirium superimposed on dementia	0.002	0.998	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.998	0.002
I27.9 Pulmonary heart disease, unspecified	0.000	0.998	0.002
M00.9 Pyogenic arthritis, unspecified	0.000	0.998	0.002
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.002	0.998	0.000
J02 Acute pharyngitis	0.002	0.998	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.002	0.998	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.002	0.998	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.000	0.998	0.002
F00.9 Dementia in Alzheimer's disease, unspecified	0.002	0.998	0.000
F05.9 Delirium, unspecified	0.002	0.998	0.000
M21.6 Other acquired deformities of ankle and foot	0.002	0.998	0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
D09.1 Other and unspecified urinary organs	0.002	0.998	0.000
D09.0 Bladder	0.002	0.998	0.000
Z92 Personal history of medical treatment	0.002	0.998	0.000
M21.7 Unequal limb length (acquired)	0.002	0.998	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.002	0.998	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.002	0.998	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.002	0.998	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.002	0.998	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.002	0.998	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.002	0.998	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.002	0.998	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.002	0.998	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.002	0.998	0.000
M85.68 Other cyst of bone (Other)	0.002	0.998	0.000
F10.4 Withdrawal state with delirium	0.002	0.998	0.000
F00 Dementia in Alzheimer's disease	0.002	0.998	0.000
K70.3 Alcoholic cirrhosis of liver	0.000	0.998	0.002
Y43.4 Immunosuppressive agents	0.000	0.998	0.002
Z31 Procreative management	0.000	0.998	0.002
M21.25 Flexion deformity (Pelvic region and thigh)	0.002	0.998	0.000
D04.7 Skin of lower limb, including hip	0.002	0.998	0.000
L85.9 Epidermal thickening, unspecified	0.002	0.998	0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.000	0.998	0.002
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.002	0.998	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.002	0.998	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.001	0.998	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.001	0.998	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.001	0.998	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.001	0.998	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.001	0.998	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.001	0.998	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.002	0.998	0.000
M21.2 Flexion deformity	0.002	0.998	0.000
M54.39 Sciatica (Site unspecified)	0.000	0.998	0.002
J92.9 Pleural plaque without asbestos	0.002	0.998	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.002	0.998	0.000
M79.61 Pain in limb (Shoulder region)	0.002	0.998	0.000
D06.7 Other parts of cervix	0.001	0.998	0.000
J02.8 Acute pharyngitis due to other specified organisms	0.001	0.998	0.000
N04.9 Unspecified	0.000	0.998	0.002
M21.73 Unequal limb length (acquired) (Forearm)	0.001	0.998	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.001	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.000	0.998	0.002
Z31.3 Other assisted fertilisation methods	0.000	0.998	0.001
Z92.5 Personal history of rehabilitation measures	0.001	0.998	0.000
F09 Unspecified organic or symptomatic mental disorder	0.001	0.998	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.001	0.998	0.000
M21.27 Flexion deformity (Ankle and foot)	0.001	0.998	0.000
G30.8 Other Alzheimer's disease	0.001	0.998	0.000
G30.1 Alzheimer's disease with late onset	0.001	0.998	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.998	0.002
M89.6 Osteopathy after poliomyelitis	0.001	0.998	0.000
M89.2 Other disorders of bone development and growth	0.001	0.998	0.000
M89.1 Epiphyseal arrest	0.001	0.998	0.000
Z31.6 General counselling and advice on procreation	0.000	0.998	0.001
M00.98 Pyogenic arthritis, unspecified (Other)	0.000	0.998	0.001
M21.76 Unequal limb length (acquired) (Lower leg)	0.001	0.998	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.001	0.998	0.000
S62.31 Fracture of other metacarpal bone (open)	0.001	0.998	0.000
H61.2 Impacted cerumen	0.002	0.998	0.000
M47.9 Spondylosis, unspecified	0.002	0.998	0.000
R49 Voice disturbances	0.002	0.998	0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.000	0.998	0.001
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.000	0.998	0.001
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.001	0.998	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.001	0.998	0.000
D38.1 Trachea, bronchus and lung	0.000	0.998	0.002
F05.0 Delirium not superimposed on dementia, so described	0.001	0.998	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.001	0.998	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.001	0.998	0.000
F07.1 Postencephalitic syndrome	0.001	0.998	0.000
M21.9 Acquired deformity of limb, unspecified	0.001	0.998	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.998	0.002
C60 Malignant neoplasm of penis	0.002	0.998	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.001	0.998	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.001	0.998	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.001	0.998	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.001	0.998	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.001	0.998	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.001	0.998	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.001	0.998	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.001	0.998	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.001	0.998	0.000
C60.1 Glans penis	0.001	0.998	0.000
C60.0 Prepuce	0.001	0.998	0.000
B18 Chronic viral hepatitis	0.000	0.998	0.001
H61 Other disorders of external ear	0.001	0.998	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.001	0.998	0.000
M21.78 Unequal limb length (acquired)-Other	0.001	0.998	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.001	0.998	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.001	0.998	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.001	0.998	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.001	0.998	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.001	0.998	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.001	0.998	0.000
D06.0 Endocervix	0.001	0.998	0.000
K70.4 Alcoholic hepatic failure	0.000	0.998	0.001
M89.5 Osteolysis	0.001	0.998	0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.001	0.998	0.000
M85.66 Other cyst of bone (Lower leg)	0.001	0.999	0.000
M89.0 Algoneurodystrophy	0.001	0.999	0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.000	0.999	0.001
Z92.9 Personal history of medical treatment, unspecified	0.001	0.999	0.000
M85.64 Other cyst of bone (Hand)	0.001	0.999	0.000
M21.4 Flat foot [pes planus] (acquired)	0.001	0.999	0.000
M89.3 Hypertrophy of bone	0.001	0.999	0.000
W19.3 Sports and athletics area	0.001	0.999	0.000
Z31.5 Genetic counselling	0.000	0.999	0.001
Z31.1 Artifical insemination	0.000	0.999	0.001
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M23.49 Loose body in knee-Unspec lig/men	0.000	0.999	0.001
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.001	0.999	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.001	0.999	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.001	0.999	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.001	0.999	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.001	0.999	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.001	0.999	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.001	0.999	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.001	0.999	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.001	0.999	0.000
D06.1 Exocervix	0.001	0.999	0.000
F05.8 Other delirium	0.001	0.999	0.000
G93.9 Disorder of brain, unspecified	0.001	0.999	0.000
H11.1 Conjunctival degenerations and deposits	0.000	0.999	0.001
I27.8 Other specified pulmonary heart diseases	0.000	0.999	0.001
M85.6 Other cyst of bone	0.001	0.999	0.000
H11 Other disorders of conjunctiva	0.000	0.999	0.001
M21.29 Flexion deformity (Site unspecified)	0.001	0.999	0.000
M21.28 Flexion deformity (Other)	0.001	0.999	0.000
M21.23 Flexion deformity (Forearm)	0.001	0.999	0.000
M21.21 Flexion deformity (Shoulder region)	0.001	0.999	0.000
M21.20 Flexion deformity (Multiple sites)	0.001	0.999	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.001	0.999	0.000
M89.38 Hypertrophy of bone (Other)	0.001	0.999	0.000
M89.98 Disorder of bone, unspecified (Other)	0.001	0.999	0.000
E06.3 Autoimmune thyroiditis	0.000	0.999	0.001
F07.0 Organic personality disorder	0.001	0.999	0.000
R49.1 Aphonia	0.001	0.999	0.000
Z92.6 Personal history of chemotherapy for neoplastic disease	0.001	0.999	0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.000	0.999	0.001
M89.19 Epiphyseal arrest (Site unspecified)	0.001	0.999	0.000
M89.18 Epiphyseal arrest (Other)	0.001	0.999	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.001	0.999	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.001	0.999	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.001	0.999	0.000
M89.14 Epiphyseal arrest (Hand)	0.001	0.999	0.000
M89.13 Epiphyseal arrest (Forearm)	0.001	0.999	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.001	0.999	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.001	0.999	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.001	0.999	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.001	0.999	0.000
M89.28 Other disorders of bone development and growth (Other)	0.001	0.999	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.001	0.999	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.001	0.999	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.001	0.999	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.001	0.999	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.001	0.999	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.001	0.999	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.001	0.999	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.001	0.999	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.001	0.999	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.001	0.999	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.001	0.999	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.001	0.999	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.001	0.999	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.001	0.999	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.001	0.999	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.001	0.999	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.001	0.999	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.001	0.999	0.000
O75.8 Other specified complications of labour and delivery	0.001	0.999	0.000
Z31.4 Procreative investigation and testing	0.000	0.999	0.001
Z49.1 Extracorporeal dialysis	0.000	0.999	0.001
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.001	0.999	0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.001	0.999	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.001	0.999	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.001	0.999	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.001	0.999	0.000
J02.0 Streptococcal pharyngitis	0.001	0.999	0.000
K29.2 Alcoholic gastritis	0.000	0.999	0.001
R49.2 Hypernasality and hyponasality	0.001	0.999	0.000
Z31.8 Other procreative management	0.000	0.999	0.001
M00.94 Pyogenic arthritis, unspecified (Hand)	0.000	0.999	0.001
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.001	0.999	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.001	0.999	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.001	0.999	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.001	0.999	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.001	0.999	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.001	0.999	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.001	0.999	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.001	0.999	0.000
C60.8 Overlapping lesion of penis	0.001	0.999	0.000
C60.2 Body of penis	0.001	0.999	0.000
M89.9 Disorder of bone, unspecified	0.001	0.999	0.000
N73.0 Acute parametritis and pelvic cellulitis	0.001	0.999	0.000
O30.1 Triplet pregnancy	0.001	0.999	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.999	0.000
M89.59 Osteolysis (Site unspecified)	0.001	0.999	0.000
M89.58 Osteolysis (Other)	0.001	0.999	0.000
M89.57 Osteolysis (Ankle and foot)	0.001	0.999	0.000
M89.56 Osteolysis (Lower leg)	0.001	0.999	0.000
M89.54 Osteolysis (Hand)	0.001	0.999	0.000
M89.53 Osteolysis (Forearm)	0.001	0.999	0.000
M89.52 Osteolysis (Upper arm)	0.001	0.999	0.000
M89.51 Osteolysis (Shoulder region)	0.001	0.999	0.000
M89.50 Osteolysis (Multiple sites)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations