TreeWAS – Variant ID: rs12230170

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
Chapter IX Diseases of the circulatory system	0.997	0.003
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.994	0.006
I60-I69 Cerebrovascular diseases	0.985	0.015
I30-I52 Other forms of heart disease	0.982	0.018
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.971	0.029
R04 Haemorrhage from respiratory passages	0.967	0.033
S60-S69 Injuries to the wrist and hand	0.965	0.035
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.964	0.036
Chapter IV Endocrine, nutritional and metabolic diseases	0.963	0.037
R07 Pain in throat and chest	0.960	0.040
Chapter I Certain infectious and parasitic diseases	0.955	0.045
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.952	0.048
S00-S09 Injuries to the head	0.951	0.049
Chapter XX External causes of morbidity and mortality	0.950	0.050
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.948	0.052
R04.0 Epistaxis	0.947	0.053
R07.3 Other chest pain	0.945	0.055
S62 Fracture at wrist and hand level	0.944	0.056
I44 Atrioventricular and left bundle-branch block	0.936	0.064
Chapter V Mental and behavioural disorders	0.935	0.065
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.928	0.072
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.919	0.081
I47 Paroxysmal tachycardia	0.914	0.086
I44.7 Left bundle-branch block, unspecified	0.912	0.088
T81 Complications of procedures, not elsewhere classified	0.906	0.094
E10-E14 Diabetes mellitus	0.904	0.096
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.902	0.098
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.897	0.103
F00-F09 Organic, including symptomatic, mental disorders	0.893	0.107
I63 Cerebral infarction	0.893	0.107
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.891	0.109
R07.0 Pain in throat	0.882	0.118
R94 Abnormal results of function studies	0.881	0.119
S62.3 Fracture of other metacarpal bone	0.880	0.120
M50-M54 Other dorsopathies	0.880	0.120
I50 Heart failure	0.878	0.122
R42 Dizziness and giddiness	0.868	0.132
Chapter II Neoplasms	0.866	0.134
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.866	0.134
S09 Other and unspecified injuries of head	0.865	0.135
R79 Other abnormal findings of blood chemistry	0.863	0.137
I67 Other cerebrovascular diseases	0.861	0.139
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.856	0.144
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.854	0.146
T81.4 Infection following a procedure, not elsewhere classified	0.853	0.147
M50 Cervical disk disorders	0.853	0.147
Q20-Q28 Congenital malformations of the circulatory system	0.852	0.148
R50-R69 General symptoms and signs	0.849	0.151
R41 Other symptoms and signs involving cognitive functions and awareness	0.847	0.153
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.845	0.155
S02 Fracture of skull and facial bones	0.843	0.157
S20-S29 Injuries to the thorax	0.840	0.160
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.839	0.161
I64 Stroke, not specified as haemorrhage or infarction	0.837	0.163
S62.30 Fracture of other metacarpal bone (closed)	0.835	0.165
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.833	0.167
R94.5 Abnormal results of liver function studies	0.832	0.168
A30-A49 Other bacterial diseases	0.831	0.168
R45 Symptoms and signs involving emotional state	0.829	0.171
F05 Delirium, not induced by alcohol and other psychoactive substances	0.829	0.171
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.829	0.171
Y83.6 Removal of other organ (partial) (total)	0.827	0.173
A00-A09 Intestinal infectious diseases	0.826	0.174
Q60-Q64 Congenital malformations of the urinary system	0.824	0.176
I31 Other diseases of pericardium	0.823	0.177
E10 Insulin-dependent diabetes mellitus	0.822	0.178
I69 Sequelae of cerebrovascular disease	0.819	0.181
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.818	0.182
R72 Abnormality of white blood cells, not elsewhere classified	0.818	0.182
E40-E46 Malnutrition	0.811	0.189
S80-S89 Injuries to the knee and lower leg	0.810	0.190
I63.9 Cerebral infarction, unspecified	0.810	0.190
E70-E90 Metabolic disorders	0.808	0.192
R79.8 Other specified abnormal findings of blood chemistry	0.807	0.193
I83 Varicose veins of lower extremities	0.805	0.195
R03 Abnormal blood-pressure reading, without diagnosis	0.804	0.196
I47.2 Ventricular tachycardia	0.804	0.196
S09.9 Unspecified injury of head	0.804	0.196
W20-W49 Exposure to inanimate mechanical forces	0.802	0.198
S90-S99 Injuries to the ankle and foot	0.802	0.198
I47.1 Supraventricular tachycardia	0.798	0.202
I35 Nonrheumatic aortic valve disorders	0.796	0.204
I85 Oesophageal varices	0.795	0.205
Chapter XXII Codes for special purposes	0.794	0.206
S62.0 Fracture of navicular [scaphoid] bone of hand	0.790	0.210
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.788	0.212
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.785	0.215
I42 Cardiomyopathy	0.784	0.216
F05.9 Delirium, unspecified	0.783	0.217
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.782	0.218
I50.1 Left ventricular failure	0.782	0.218
Q21 Congenital malformations of cardiac septa	0.780	0.220
T15-T19 Effects of foreign body entering through natural orifice	0.780	0.220
R00 Abnormalities of heart beat	0.780	0.220
S62.6 Fracture of other finger	0.777	0.223
R63 Symptoms and signs concerning food and fluid intake	0.772	0.228
M50.1 Cervical disk disorder with radiculopathy	0.771	0.229
C78.2 Secondary malignant neoplasm of pleura	0.770	0.230
R53 Malaise and fatigue	0.768	0.232
D00-D09 In situ neoplasms	0.768	0.232
T81.8 Other complications of procedures, not elsewhere classified	0.766	0.234
E11 Non-insulin-dependent diabetes mellitus	0.764	0.236
I65.2 Occlusion and stenosis of carotid artery	0.764	0.236
E20-E35 Disorders of other endocrine glands	0.763	0.237
S62.5 Fracture of thumb	0.762	0.238
B15-B19 Viral hepatitis	0.761	0.239
A41 Other septicaemia	0.759	0.241
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.756	0.244
I50.9 Heart failure, unspecified	0.754	0.246
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.752	0.248
B99-B99 Other infectious diseases	0.750	0.250
T85 Complications of other internal prosthetic devices, implants and grafts	0.746	0.254
M51 Other intervertebral disk disorders	0.744	0.256
R07.1 Chest pain on breathing	0.743	0.257
M65-M68 Disorders of synovium and tendon	0.742	0.258
S70-S79 Injuries to the hip and thigh	0.742	0.258
Q80-Q89 Other congenital malformations	0.741	0.259
R26 Abnormalities of gait and mobility	0.740	0.260
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.739	0.261
R63.4 Abnormal weight loss	0.737	0.263
M50.3 Other cervical disk degeneration	0.737	0.263
R44 Other symptoms and signs involving general sensations and perceptions	0.736	0.264
E50-E64 Other nutritional deficiencies	0.736	0.264
I05-I09 Chronic rheumatic heart diseases	0.734	0.266
M50.2 Other cervical disk displacement	0.733	0.267
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.732	0.268
Q61 Cystic kidney disease	0.732	0.268
T82.1 Mechanical complication of cardiac electronic device	0.730	0.270
R45.1 Restlessness and agitation	0.730	0.270
F03 Unspecified dementia	0.730	0.270
Q21.1 Atrial septal defect	0.729	0.271
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.728	0.272
B35-B49 Mycoses	0.727	0.273
C78.7 Secondary malignant neoplasm of liver	0.725	0.275
Chapter VI Diseases of the nervous system	0.724	0.276
A41.9 Septicaemia, unspecified	0.724	0.276
E10.3 With ophthalmic complications	0.723	0.277
I46 Cardiac arrest	0.721	0.279
A08 Viral and other specified intestinal infections	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
R41.0 Disorientation, unspecified	0.717	0.283
T33-T35 Frostbite	0.716	0.284
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284
T00-T07 Injuries involving multiple body regions	0.716	0.284
S10-S19 Injuries to the neck	0.716	0.284
I31.9 Disease of pericardium, unspecified	0.716	0.284
I00-I02 Acute rheumatic fever	0.715	0.285
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.715	0.285
S60 Superficial injury of wrist and hand	0.715	0.285
Y60-Y69 Misadventures to patients during surgical and medical care	0.715	0.285
T79-T79 Certain early complications of trauma	0.714	0.286
I62 Other nontraumatic intracranial haemorrhage	0.713	0.286
R54 Senility	0.713	0.287
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.712	0.287
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.712	0.288
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.712	0.288
R09.2 Respiratory arrest	0.712	0.288
I95-I99 Other and unspecified disorders of the circulatory system	0.711	0.289
R04.2 Haemoptysis	0.710	0.290
V20-V29 Motorcycle rider injured in transport accident	0.709	0.291
C15-C26 Malignant neoplasms of digestive organs	0.709	0.291
T81.3 Disruption of operation wound, not elsewhere classified	0.708	0.292
R94.3 Abnormal results of cardiovascular function studies	0.708	0.292
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.707	0.293
R47-R49 Symptoms and signs involving speech and voice	0.707	0.293
I68 Cerebrovascular disorders in diseases classified elsewhere	0.706	0.294
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.706	0.294
R87 Abnormal findings in specimens from female genital organs	0.706	0.294
R73 Elevated blood glucose level	0.706	0.294
F40-F48 Neurotic, stress-related and somatoform disorders	0.705	0.295
I52 Other heart disorders in diseases classified elsewhere	0.704	0.296
I48 Atrial fibrillation and flutter	0.704	0.296
I43 Cardiomyopathy in diseases classified elsewhere	0.704	0.296
I41 Myocarditis in diseases classified elsewhere	0.704	0.296
I40 Acute myocarditis	0.704	0.296
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.704	0.296
I37 Pulmonary valve disorders	0.704	0.296
I36 Nonrheumatic tricuspid valve disorders	0.704	0.296
I33 Acute and subacute endocarditis	0.704	0.296
I32 Pericarditis in diseases classified elsewhere	0.704	0.296
I30 Acute pericarditis	0.704	0.296
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.704	0.296
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.704	0.296
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.703	0.297
A50-A64 Infections with a predominantly sexual mode of transmission	0.703	0.297
Q50-Q56 Congenital malformations of genital organs	0.703	0.297
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.703	0.297
E46 Unspecified protein-energy malnutrition	0.702	0.298
S20 Superficial injury of thorax	0.700	0.300
I45 Other conduction disorders	0.700	0.300
I80 Phlebitis and thrombophlebitis	0.699	0.301
B25-B34 Other viral diseases	0.698	0.302
I67.9 Cerebrovascular disease, unspecified	0.697	0.303
S02.2 Fracture of nasal bones	0.696	0.303
T88 Other complications of surgical and medical care, not elsewhere classified	0.696	0.304
T87 Complications peculiar to reattachment and amputation	0.696	0.304
T86 Failure and rejection of transplanted organs and tissues	0.696	0.304
T80 Complications following infusion, transfusion and therapeutic injection	0.696	0.304
I70-I79 Diseases of arteries, arterioles and capillaries	0.695	0.305
R04.9 Haemorrhage from respiratory passages, unspecified	0.694	0.306
R04.8 Haemorrhage from other sites in respiratory passages	0.694	0.306
R04.1 Haemorrhage from throat	0.694	0.306
S06 Intracranial injury	0.693	0.306
I67.1 Cerebral aneurysm, nonruptured	0.692	0.308
S69 Other and unspecified injuries of wrist and hand	0.692	0.308
S68 Traumatic amputation of wrist and hand	0.692	0.308
S67 Crushing injury of wrist and hand	0.692	0.308
S65 Injury of blood vessels at wrist and hand level	0.692	0.308
S64 Injury of nerves at wrist and hand level	0.692	0.308
R46 Symptoms and signs involving appearance and behaviour	0.691	0.309
R43 Disturbances of smell and taste	0.691	0.309
I44.0 Atrioventricular block, first degree	0.691	0.309
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.691	0.309
I81 Portal vein thrombosis	0.690	0.310
I85.9 Oesophageal varices without bleeding	0.689	0.311
V10-V19 Pedal cyclist injured in transport accident	0.687	0.313
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.686	0.314
B90-B94 Sequelae of infectious and parasitic diseases	0.685	0.315
B85-B89 Pediculosis, acariasis and other infestations	0.685	0.315
B65-B83 Helminthiases	0.685	0.315
B50-B64 Protozoal diseases	0.685	0.315
B20-B24 Human immunodeficiency virus [HIV] disease	0.685	0.315
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.685	0.315
A80-A89 Viral infections of the central nervous system	0.685	0.315
A75-A79 Rickettsioses	0.685	0.315
A70-A74 Other diseases caused by chlamydiae	0.685	0.315
A65-A69 Other spirochaetal diseases	0.685	0.315
A20-A28 Certain zoonotic bacterial diseases	0.685	0.315
A15-A19 Tuberculosis	0.685	0.315
E13 Other specified diabetes mellitus	0.685	0.315
I69.1 Sequelae of intracerebral haemorrhage	0.684	0.316
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.684	0.316
R09.1 Pleurisy	0.683	0.317
S62.60 Fracture of other finger (closed)	0.683	0.317
R25 Abnormal involuntary movements	0.683	0.317
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.683	0.317
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.683	0.317
Q38-Q45 Other congenital malformations of the digestive system	0.683	0.317
Q35-Q37 Cleft lip and cleft palate	0.683	0.317
Q30-Q34 Congenital malformations of the respiratory system	0.683	0.317
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.683	0.317
Q00-Q07 Congenital malformations of the nervous system	0.683	0.317
S08 Traumatic amputation of part of head	0.681	0.318
S07 Crushing injury of head	0.681	0.318
S05 Injury of eye and orbit	0.681	0.318
S04 Injury of cranial nerves	0.681	0.318
S03 Dislocation, sprain and strain of joints and ligaments of head	0.681	0.318
B95-B98 Bacterial, viral and other infectious agents	0.682	0.318
Y35-Y36 Legal intervention and operations of war	0.681	0.318
Y10-Y34 Event of undetermined intent	0.681	0.318
Y00-Y09 Assault	0.681	0.318
X85-X99 Assault	0.681	0.318
X60-X84 Intentional self-harm	0.681	0.318
X58-X59 Accidental exposure to other and unspecified factors	0.681	0.318
X50-X57 Overexertion, travel and privation	0.681	0.318
X40-X49 Accidental poisoning by and exposure to noxious substances	0.681	0.318
X30-X39 Exposure to forces of nature	0.681	0.318
X20-X29 Contact with venomous animals and plants	0.681	0.318
X10-X19 Contact with heat and hot substances	0.681	0.318
X00-X09 Exposure to smoke, fire and flames	0.681	0.318
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.681	0.318
W75-W84 Other accidental threats to breathing	0.681	0.318
W65-W74 Accidental drowning and submersion	0.681	0.318
W50-W64 Exposure to animate mechanical forces	0.681	0.318
V98-V99 Other and unspecified transport accidents	0.681	0.318
V95-V97 Air and space transport accidents	0.681	0.318
V90-V94 Water transport accidents	0.681	0.318
V80-V89 Other land transport accidents	0.681	0.318
V70-V79 Bus occupant injured in transport accident	0.681	0.318
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.681	0.318
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.681	0.318
V40-V49 Car occupant injured in transport accident	0.681	0.318
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.681	0.318
V01-V09 Pedestrian injured in transport accident	0.681	0.318
F80-F89 Disorders of psychological development	0.681	0.319
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.681	0.319
R02 Gangrene, not elsewhere classified	0.680	0.320
E86 Volume depletion	0.680	0.320
R78 Findings of drugs and other substances, not normally found in blood	0.680	0.320
R77 Other abnormalities of plasma proteins	0.680	0.320
R76 Other abnormal immunological findings in serum	0.680	0.320
R74 Abnormal serum enzyme levels	0.680	0.320
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.680	0.320
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.680	0.320
R71 Abnormality of red blood cells	0.680	0.320
M45-M49 Spondylopathies	0.679	0.321
E83 Disorders of mineral metabolism	0.679	0.321
R93 Abnormal findings on diagnostic imaging of other body structures	0.678	0.322
D05 Carcinoma in situ of breast	0.678	0.322
M00-M03 Infectious arthropathies	0.678	0.322
S62.8 Fracture of other and unspecified parts of wrist and hand	0.676	0.323
S62.7 Multiple fractures of fingers	0.676	0.323
S62.4 Multiple fractures of metacarpal bones	0.676	0.323
S62.2 Fracture of first metacarpal bone	0.676	0.323
S62.1 Fracture of other carpal bone(s)	0.676	0.323
S01 Open wound of head	0.676	0.324
R00.0 Tachycardia, unspecified	0.673	0.327
W22 Striking against or struck by other objects	0.673	0.327
S02.5 Fracture of tooth	0.671	0.329
I44.6 Other and unspecified fascicular block	0.671	0.329
I44.5 Left posterior fascicular block	0.671	0.329
I44.4 Left anterior fascicular block	0.671	0.329
I44.3 Other and unspecified atrioventricular block	0.671	0.329
Chapter X Diseases of the respiratory system	0.671	0.329
R01 Cardiac murmurs and other cardiac sounds	0.671	0.329
S00 Superficial injury of head	0.671	0.329
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.671	0.329
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.670	0.329
F70-F79 Mental retardation	0.670	0.329
F60-F69 Disorders of adult personality and behaviour	0.670	0.329
M54 Dorsalgia	0.669	0.331
I61 Intracerebral haemorrhage	0.669	0.331
I35.9 Aortic valve disorder, unspecified	0.668	0.332
R52 Pain, not elsewhere classified	0.668	0.332
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.666	0.334
F00 Dementia in Alzheimer's disease	0.666	0.334
R92 Abnormal findings on diagnostic imaging of breast	0.665	0.334
C79 Secondary malignant neoplasm of other sites	0.665	0.335
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.665	0.335
C51-C58 Malignant neoplasms of female genital organs	0.663	0.337
R09.0 Asphyxia	0.662	0.338
E16 Other disorders of pancreatic internal secretion	0.662	0.338
M80-M85 Disorders of bone density and structure	0.662	0.338
G30-G32 Other degenerative diseases of the nervous system	0.662	0.338
R90 Abnormal findings on diagnostic imaging of central nervous system	0.661	0.339
F99-F99 Unspecified mental disorder	0.661	0.339
I67.8 Other specified cerebrovascular diseases	0.660	0.340
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.660	0.340
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.659	0.341
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.659	0.341
T82.4 Mechanical complication of vascular dialysis catheter	0.659	0.341
T82.3 Mechanical complication of other vascular grafts	0.659	0.341
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.659	0.341
T82.0 Mechanical complication of heart valve prosthesis	0.659	0.341
R50 Fever of unknown origin	0.658	0.342
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.658	0.342
I47.9 Paroxysmal tachycardia, unspecified	0.655	0.345
I47.0 Reentry ventricular arrhythmia	0.655	0.345
W00-W19 Falls	0.655	0.345
R55 Syncope and collapse	0.655	0.345
E27 Other disorders of adrenal gland	0.655	0.345
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.654	0.346
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.654	0.346
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.654	0.346
I42.9 Cardiomyopathy, unspecified	0.654	0.346
S22 Fracture of rib(s), sternum and thoracic spine	0.654	0.346
T66-T78 Other and unspecified effects of external causes	0.650	0.350
E10.5 With peripheral circulatory complications	0.649	0.350
T81.9 Unspecified complication of procedure	0.649	0.350
T81.7 Vascular complications following a procedure, not elsewhere classified	0.649	0.350
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.649	0.350
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.649	0.350
S02.1 Fracture of base of skull	0.649	0.351
R68 Other general symptoms and signs	0.648	0.351
E12 Malnutrition-related diabetes mellitus	0.648	0.352
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.647	0.353
I88 Nonspecific lymphadenitis	0.647	0.353
S40-S49 Injuries to the shoulder and upper arm	0.645	0.355
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.644	0.356
I86 Varicose veins of other sites	0.644	0.356
M91-M94 Chondropathies	0.643	0.357
M60-M63 Disorders of muscles	0.643	0.357
F01 Vascular dementia	0.641	0.359
I87 Other disorders of veins	0.641	0.359
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.640	0.359
F02 Dementia in other diseases classified elsewhere	0.640	0.359
F09 Unspecified organic or symptomatic mental disorder	0.640	0.359
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.640	0.359
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.640	0.360
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.640	0.360
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.640	0.360
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.640	0.360
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.640	0.360
A08.4 Viral intestinal infection, unspecified	0.640	0.360
E10.1 With ketoacidosis	0.639	0.361
S02.3 Fracture of orbital floor	0.639	0.361
E87 Other disorders of fluid, electrolyte and acid-base balance	0.639	0.361
S92 Fracture of foot, except ankle	0.637	0.363
R91 Abnormal findings on diagnostic imaging of lung	0.636	0.364
R26.2 Difficulty in walking, not elsewhere classified	0.636	0.364
I63.8 Other cerebral infarction	0.635	0.365
I35.2 Aortic (valve) stenosis with insufficiency	0.634	0.366
R27 Other lack of coordination	0.633	0.367
J90-J94 Other diseases of pleura	0.633	0.367
D05.9 Carcinoma in situ of breast, unspecified	0.632	0.368
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.632	0.368
R94.8 Abnormal results of function studies of other organs and systems	0.631	0.368
R94.7 Abnormal results of other endocrine function studies	0.631	0.368
R94.6 Abnormal results of thyroid function studies	0.631	0.368
R94.4 Abnormal results of kidney function studies	0.631	0.368
R94.2 Abnormal results of pulmonary function studies	0.631	0.368
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.631	0.368
R94.0 Abnormal results of function studies of central nervous system	0.631	0.368
I85.0 Oesophageal varices with bleeding	0.631	0.369
S62.31 Fracture of other metacarpal bone (open)	0.631	0.369
S63.6 Sprain and strain of finger(s)	0.631	0.369
M53 Other dorsopathies, not elsewhere classified	0.631	0.369
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.631	0.369
Q61.3 Polycystic kidney, unspecified	0.630	0.370
E11.5 With peripheral circulatory complications	0.630	0.370
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.629	0.371
E11.6 With other specified complications	0.629	0.371
I34 Nonrheumatic mitral valve disorders	0.628	0.372
I67.2 Cerebral atherosclerosis	0.628	0.372
M65 Synovitis and tenosynovitis	0.627	0.372
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.626	0.374
R80 Isolated proteinuria	0.626	0.374
E14 Unspecified diabetes mellitus	0.626	0.374
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.625	0.375
S81 Open wound of lower leg	0.624	0.376
I82 Other venous embolism and thrombosis	0.624	0.376
T18 Foreign body in alimentary tract	0.622	0.377
M86-M90 Other osteopathies	0.622	0.378
I44.2 Atrioventricular block, complete	0.621	0.378
B18 Chronic viral hepatitis	0.621	0.378
A04 Other bacterial intestinal infections	0.621	0.379
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.621	0.379
C40-C41 Malignant neoplasms of bone and articular cartilage	0.621	0.379
R09.3 Abnormal sputum	0.621	0.379
E11.1 With ketoacidosis	0.621	0.379
S09.8 Other specified injuries of head	0.620	0.380
S09.7 Multiple injuries of head	0.620	0.380
S09.2 Traumatic rupture of ear drum	0.620	0.380
S09.1 Injury of muscle and tendon of head	0.620	0.380
S09.0 Injury of blood vessels of head, not elsewhere classified	0.620	0.380
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.619	0.380
I60 Subarachnoid haemorrhage	0.619	0.381
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.619	0.381
R79.0 Abnormal level of blood mineral	0.619	0.381
R87.6 Abnormal cytological findings	0.618	0.382
I67.7 Cerebral arteritis, not elsewhere classified	0.617	0.383
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.617	0.383
I67.5 Moyamoya disease	0.617	0.383
I67.4 Hypertensive encephalopathy	0.617	0.383
I67.3 Progressive vascular leukoencephalopathy	0.617	0.383
I67.0 Dissection of cerebral arteries, nonruptured	0.617	0.383
M40-M43 Deforming dorsopathies	0.616	0.384
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.616	0.384
S62.51 Fracture of thumb (open)	0.614	0.386
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.614	0.386
I65.8 Occlusion and stenosis of other precerebral artery	0.614	0.386
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.614	0.386
I65.1 Occlusion and stenosis of basilar artery	0.614	0.386
I65.0 Occlusion and stenosis of vertebral artery	0.614	0.386
J90 Pleural effusion, not elsewhere classified	0.614	0.386
E83.1 Disorders of iron metabolism	0.613	0.387
S80 Superficial injury of lower leg	0.612	0.388
M50.9 Cervical disk disorder, unspecified	0.611	0.389
M50.8 Other cervical disk disorders	0.611	0.389
Q28 Other congenital malformations of circulatory system	0.611	0.389
Q27 Other congenital malformations of peripheral vascular system	0.611	0.389
Q26 Congenital malformations of great veins	0.611	0.389
Q25 Congenital malformations of great arteries	0.611	0.389
Q24 Other congenital malformations of heart	0.611	0.389
Q23 Congenital malformations of aortic and mitral valves	0.611	0.389
Q22 Congenital malformations of pulmonary and tricuspid valves	0.611	0.389
Q20 Congenital malformations of cardiac chambers and connexions	0.611	0.389
D03 Melanoma in situ	0.611	0.389
M50.0 Cervical disk disorder with myelopathy	0.611	0.389
I44.1 Atrioventricular block, second degree	0.610	0.390
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.609	0.390
S90 Superficial injury of ankle and foot	0.609	0.391
D37-D48 Neoplasms of uncertain or unknown behaviour	0.609	0.391
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.609	0.391
R62 Lack of expected normal physiological development	0.609	0.391
R57 Shock, not elsewhere classified	0.609	0.391
R64 Cachexia	0.609	0.391
R58 Haemorrhage, not elsewhere classified	0.609	0.391
D04 Carcinoma in situ of skin	0.608	0.392
R41.2 Retrograde amnesia	0.608	0.392
R41.1 Anterograde amnesia	0.608	0.392
W44 Foreign body entering into or through eye or natural orifice	0.608	0.392
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.607	0.393
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.605	0.395
C25 Malignant neoplasm of pancreas	0.605	0.395
S02.9 Fracture of skull and facial bones, part unspecified	0.604	0.395
S02.8 Fractures of other skull and facial bones	0.604	0.395
S02.7 Multiple fractures involving skull and facial bones	0.604	0.395
S02.6 Fracture of mandible	0.604	0.395
S02.0 Fracture of vault of skull	0.604	0.395
E10.4 With neurological complications	0.604	0.396
G80-G83 Cerebral palsy and other paralytic syndromes	0.604	0.396
S66 Injury of muscle and tendon at wrist and hand level	0.603	0.397
B99 Other and unspecified infectious diseases	0.603	0.397
S29 Other and unspecified injuries of thorax	0.602	0.398
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.602	0.398
S26 Injury of heart	0.602	0.398
S25 Injury of blood vessels of thorax	0.602	0.398
S24 Injury of nerves and spinal cord at thorax level	0.602	0.398
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.602	0.398
S21 Open wound of thorax	0.602	0.398
C76 Malignant neoplasm of other and ill-defined sites	0.602	0.398
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.601	0.399
S20.2 Contusion of thorax	0.600	0.400

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations