TreeWAS – Variant ID: rs12261764

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I69.3 Sequelae of cerebral infarction	0.000	0.985	0.015
I69 Sequelae of cerebrovascular disease	0.000	0.986	0.014
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.987	0.013
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.988	0.012
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.988	0.012
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.988	0.012
I51.8 Other ill-defined heart diseases	0.000	0.989	0.011
I42.9 Cardiomyopathy, unspecified	0.009	0.991	0.000
F05.9 Delirium, unspecified	0.000	0.991	0.009
S82.20 Fracture of shaft of tibia (closed)	0.000	0.991	0.009
S83.2 Tear of meniscus, current	0.007	0.993	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.007	0.993	0.000
I42 Cardiomyopathy	0.007	0.993	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.007	0.993	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.994	0.006
I42.4 Endocardial fibroelastosis	0.006	0.994	0.000
M25.46 Effusion of joint (Lower leg)	0.000	0.994	0.006
I42.2 Other hypertrophic cardiomyopathy	0.006	0.994	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.995	0.005
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.995	0.005
I42.7 Cardiomyopathy due to drugs and other external agents	0.005	0.995	0.000
I42.5 Other restrictive cardiomyopathy	0.005	0.995	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.005	0.995	0.000
K80.4 Calculus of bile duct with cholecystitis	0.005	0.995	0.000
I87.1 Compression of vein	0.000	0.995	0.005
D68.5 Primary Thrombophilia	0.000	0.995	0.005
K55.2 Angiodysplasia of colon	0.000	0.995	0.005
S82.2 Fracture of shaft of tibia	0.000	0.995	0.005
I42.8 Other cardiomyopathies	0.005	0.995	0.000
D68.6 Other Thrombophilia	0.000	0.995	0.005
S22.4 Multiple fractures of ribs	0.000	0.995	0.005
I42.6 Alcoholic cardiomyopathy	0.004	0.995	0.000
H90.2 Conductive hearing loss, unspecified	0.000	0.995	0.005
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.000	0.996	0.004
E05.0 Thyrotoxicosis with diffuse goitre	0.004	0.996	0.000
I67.9 Cerebrovascular disease, unspecified	0.000	0.996	0.004
S82.21 Fracture of shaft of tibia (open)	0.000	0.996	0.004
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.004	0.996	0.000
D68 Other coagulation defects	0.000	0.996	0.004
T88.4 Failed or difficult intubation	0.004	0.996	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.004	0.996	0.000
Z90.5 Acquired absence of kidney	0.000	0.996	0.004
D68.9 Coagulation defect, unspecified	0.000	0.996	0.004
C16.9 Stomach, unspecified	0.000	0.996	0.004
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.996	0.004
S22.41 Multiple fractures of ribs (open)	0.000	0.996	0.003
I87.8 Other specified disorders of veins	0.000	0.996	0.003
S22.20 Fracture of sternum (closed)	0.000	0.997	0.003
H58.8 Visual disturbances in diseases classified elsewhere	0.003	0.997	0.000
S83.3 Tear of articular cartilage of knee, current	0.003	0.997	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.003	0.997	0.000
S83.7 Injury to multiple structures of knee	0.003	0.997	0.000
D68.8 Other specified coagulation defects	0.000	0.997	0.003
S22.2 Fracture of sternum	0.000	0.997	0.003
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.997	0.003
C16.5 Lesser curvature of stomach, unspecified	0.000	0.997	0.003
I61 Intracerebral haemorrhage	0.000	0.997	0.003
S83.1 Dislocation of knee	0.003	0.997	0.000
S83.0 Dislocation of patella	0.003	0.997	0.000
H57.0 Anomalies of pupillary function	0.003	0.997	0.000
D68.0 Von Willebrand's disease	0.000	0.997	0.003
Z85.3 Personal history of malignant neoplasm of breast	0.000	0.997	0.003
S22.1 Multiple fractures of thoracic spine	0.000	0.997	0.003
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.997	0.003
D68.1 Hereditary factor XI deficiency	0.000	0.997	0.003
J93.9 Pneumothorax, unspecified	0.000	0.997	0.003
S83.6 Sprain and strain of other and unspecified parts of knee	0.003	0.997	0.000
I60-I69 Cerebrovascular diseases	0.000	0.997	0.003
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.003	0.997	0.000
I87 Other disorders of veins	0.000	0.997	0.003
C16 Malignant neoplasm of stomach	0.000	0.997	0.003
M10.96 Gout, unspecified (Lower leg)	0.003	0.997	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.997	0.003
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.997	0.003
I42.0 Dilated cardiomyopathy	0.003	0.997	0.000
N02.9 Unspecified	0.000	0.997	0.003
T78.4 Allergy, unspecified	0.003	0.997	0.000
K25.7 Chronic without haemorrhage or perforation	0.003	0.997	0.000
I62 Other nontraumatic intracranial haemorrhage	0.000	0.997	0.003
I60 Subarachnoid haemorrhage	0.000	0.997	0.003
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.997	0.003
F05 Delirium, not induced by alcohol and other psychoactive substances	0.000	0.997	0.003
R12 Heartburn	0.003	0.997	0.000
S82.40 Fracture of fibula alone (closed)	0.003	0.997	0.000
D68.4 Acquired coagulation factor deficiency	0.000	0.997	0.003
H57 Other disorders of eye and adnexa	0.003	0.997	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.003	0.997	0.000
S22.21 Fracture of sternum (open)	0.000	0.997	0.002
C16.2 Body of stomach	0.000	0.997	0.003
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.997	0.003
M31.6 Other giant cell arteritis	0.000	0.997	0.003
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.997	0.003
S22.9 Fracture of bony thorax, part unspecified	0.000	0.997	0.002
S22.8 Fracture of other parts of bony thorax	0.000	0.997	0.002
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.997	0.003
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.997	0.002
S22.5 Flail chest	0.000	0.997	0.002
S90.8 Other superficial injuries of ankle and foot	0.003	0.997	0.000
C16.3 Pyloric antrum	0.000	0.997	0.002
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.997	0.003
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.002	0.997	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.997	0.002
K22.5 Diverticulum of oesophagus, acquired	0.003	0.997	0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.000	0.997	0.003
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.997	0.002
I67 Other cerebrovascular diseases	0.000	0.998	0.002
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.002	0.998	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.998	0.002
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.998	0.002
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
I87.0 Postphlebitic syndrome	0.000	0.998	0.002
M14.6 Neuropathic arthropathy	0.002	0.998	0.000
C16.8 Overlapping lesion of stomach	0.000	0.998	0.002
C16.4 Pylorus	0.000	0.998	0.002
C16.1 Fundus of stomach	0.000	0.998	0.002
H93.1 Tinnitus	0.000	0.998	0.002
I61.8 Other intracerebral haemorrhage	0.000	0.998	0.002
I87.9 Disorder of vein, unspecified	0.000	0.998	0.002
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
I62.1 Nontraumatic extradural haemorrhage	0.000	0.998	0.002
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.998	0.002
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.998	0.002
M89.87 Other specified disorders of bone (Ankle and foot)	0.000	0.998	0.002
C16.0 Cardia	0.000	0.998	0.002
D12.8 Rectum	0.002	0.998	0.000
M94.96 Disorder of cartilage, unspecified (Lower leg)	0.000	0.998	0.002
C16.6 Greater curvature of stomach, unspecified	0.000	0.998	0.002
F05.0 Delirium not superimposed on dementia, so described	0.000	0.998	0.002
S22.3 Fracture of rib	0.000	0.998	0.002
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.998	0.002
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.998	0.002
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.998	0.002
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.998	0.002
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.998	0.002
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.998	0.002
H57.8 Other specified disorders of eye and adnexa	0.002	0.998	0.000
S22.51 Flail chest (open)	0.000	0.998	0.002
F05.1 Delirium superimposed on dementia	0.000	0.998	0.002
I22.9 Subsequent myocardial infarction of unspecified site	0.002	0.998	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.998	0.002
S22.50 Flail chest (closed)	0.000	0.998	0.002
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.998	0.002
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.998	0.002
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.002	0.998	0.000
I60.8 Other subarachnoid haemorrhage	0.000	0.998	0.002
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.998	0.002
C49.0 Connective and soft tissue of head, face and neck	0.000	0.998	0.002
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.998	0.002
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.000	0.998	0.002
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.002	0.998	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.002	0.998	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.002	0.998	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.998	0.002
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.998	0.002
I67.5 Moyamoya disease	0.000	0.998	0.002
I67.4 Hypertensive encephalopathy	0.000	0.998	0.002
I67.3 Progressive vascular leukoencephalopathy	0.000	0.998	0.002
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.998	0.002
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.998	0.002
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
I68.0 Cerebral amyloid angiopathy	0.000	0.998	0.002
T85.4 Mechanical complication of breast prosthesis and implant	0.000	0.998	0.002
N28.9 Disorder of kidney and ureter, unspecified	0.000	0.998	0.002
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.002	0.998	0.000
N48.1 Balanoposthitis	0.000	0.998	0.002
N11 Chronic tubulo-interstitial nephritis	0.000	0.998	0.002
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
K90.0 Coeliac disease	0.002	0.998	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.998	0.002
T21.2 Burn of second degree of trunk	0.002	0.998	0.000
D45 Polycythaemia vera	0.000	0.998	0.002
C49.1 Connective and soft tissue of upper limb, including shoulder	0.000	0.998	0.002
G58.8 Other specified mononeuropathies	0.000	0.998	0.002
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
C49.4 Connective and soft tissue of abdomen	0.000	0.998	0.002
C77.1 Intrathoracic lymph nodes	0.000	0.998	0.002
F05.8 Other delirium	0.000	0.998	0.002
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.001	0.998	0.001
K51.4 Pseudopolyposis of colon	0.002	0.998	0.000
N10-N16 Renal tubulo-interstitial diseases	0.000	0.998	0.002
M79.18 Myalgia (Other)	0.000	0.998	0.002
M89.88 Other specified disorders of bone (Other)	0.000	0.998	0.002
C49.9 Connective and soft tissue, unspecified	0.000	0.998	0.002
C49.8 Overlapping lesion of connective and soft tissue	0.000	0.998	0.002
C49.6 Connective and soft tissue of trunk, unspecified	0.000	0.998	0.002
J02.9 Acute pharyngitis, unspecified	0.000	0.998	0.002
L73.2 Hidradenitis suppurativa	0.000	0.998	0.002
S90.0 Contusion of ankle	0.002	0.998	0.000
S22.31 Fracture of rib (open)	0.000	0.998	0.002
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.998	0.002
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.998	0.002
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.998	0.002
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.998	0.002
D59.1 Other autoimmune haemolytic anaemias	0.000	0.998	0.002
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.998	0.002
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
S22.0 Fracture of thoracic vertebra	0.000	0.998	0.002
C18.0 Caecum	0.002	0.998	0.000
D39.1 Ovary	0.000	0.998	0.002
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.998	0.002
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.998	0.002
M25.4 Effusion of joint	0.000	0.998	0.002
L05.9 Pilonidal cyst without abscess	0.000	0.998	0.002
T21 Burn and corrosion of trunk	0.002	0.998	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.998	0.001
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.000	0.998	0.002
G58.9 Mononeuropathy, unspecified	0.000	0.998	0.002
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
Q43.0 Meckel's diverticulum	0.002	0.998	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.998	0.002
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.998	0.002
N11.8 Other chronic tubulo-interstitial nephritis	0.000	0.998	0.002
N11.1 Chronic obstructive pyelonephritis	0.000	0.998	0.002
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.002	0.998	0.000
H55-H59 Other disorders of eye and adnexa	0.002	0.998	0.000
C49.5 Connective and soft tissue of pelvis	0.000	0.998	0.002
M89.8 Other specified disorders of bone	0.000	0.998	0.002
T25 Burn and corrosion of ankle and foot	0.002	0.998	0.000
K72.9 Hepatic failure, unspecified	0.000	0.998	0.002
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.002	0.998	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.000	0.998	0.002
R47.0 Dysphasia and aphasia	0.000	0.998	0.002
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.002	0.998	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.000	0.998	0.002
T25.2 Burn of second degree of ankle and foot	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.002	0.998	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.002	0.998	0.000
M17.0 Primary gonarthrosis, bilateral	0.000	0.998	0.002
S22.01 Fracture of thoracic vertebra (open)	0.000	0.998	0.001
D35.1 Parathyroid gland	0.000	0.998	0.002
I67.1 Cerebral aneurysm, nonruptured	0.000	0.998	0.002
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.002	0.998	0.000
J93 Pneumothorax	0.000	0.998	0.002
N15 Other renal tubulo-interstitial diseases	0.000	0.998	0.001
M47.99 Spondylosis, unspecified (Site unspecified)	0.002	0.998	0.000
C49.3 Connective and soft tissue of thorax	0.000	0.998	0.001
G58.7 Mononeuritis multiplex	0.000	0.998	0.002
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.998	0.001
T25.0 Burn of unspecified degree of ankle and foot	0.001	0.998	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.000	0.998	0.001
S91 Open wound of ankle and foot	0.002	0.998	0.000
M25.41 Effusion of joint (Shoulder region)	0.000	0.998	0.001
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.998	0.002
M25.49 Effusion of joint (Site unspecified)	0.000	0.998	0.001
M25.48 Effusion of joint (Other)	0.000	0.998	0.001
M89.81 Other specified disorders of bone (Shoulder region)	0.000	0.998	0.001
S92.51 Fracture of other toe (open)	0.001	0.998	0.000
T21.7 Corrosion of third degree of trunk	0.001	0.998	0.000
T21.6 Corrosion of second degree of trunk	0.001	0.998	0.000
T21.5 Corrosion of first degree of trunk	0.001	0.998	0.000
T21.4 Corrosion of unspecified degree of trunk	0.001	0.998	0.000
T21.3 Burn of third degree of trunk	0.001	0.998	0.000
T21.1 Burn of first degree of trunk	0.001	0.998	0.000
M94.88 Other specified disorders of cartilage (Other)	0.000	0.998	0.001
S92 Fracture of foot, except ankle	0.002	0.998	0.000
M89.84 Other specified disorders of bone (Hand)	0.000	0.998	0.001
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.998	0.000
C44.7 Skin of lower limb, including hip	0.002	0.998	0.000
H93.8 Other specified disorders of ear	0.000	0.998	0.001
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.001	0.998	0.000
M94.9 Disorder of cartilage, unspecified	0.000	0.998	0.001
T21.0 Burn of unspecified degree of trunk	0.001	0.998	0.000
S97 Crushing injury of ankle and foot	0.001	0.998	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.998	0.001
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.998	0.001
Q28.2 Arteriovenous malformation of cerebral vessels	0.001	0.998	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.002	0.998	0.000
N10 Acute tubulo-interstitial nephritis	0.000	0.998	0.001
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.001	0.998	0.000
M25.44 Effusion of joint (Hand)	0.000	0.998	0.001
M25.40 Effusion of joint (Multiple sites)	0.000	0.998	0.001
M79.69 Pain in limb (Site unspecified)	0.000	0.998	0.002
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.998	0.002
J93.0 Spontaneous tension pneumothorax	0.000	0.998	0.001
R56.8 Other and unspecified convulsions	0.000	0.998	0.002
M25.42 Effusion of joint (Upper arm)	0.000	0.999	0.001
M89.89 Other specified disorders of bone (Site unspecified)	0.000	0.999	0.001
M89.83 Other specified disorders of bone (Forearm)	0.000	0.999	0.001
M89.82 Other specified disorders of bone (Upper arm)	0.000	0.999	0.001
M89.80 Other specified disorders of bone (Multiple sites)	0.000	0.999	0.001
M47.2 Other spondylosis with radiculopathy	0.001	0.999	0.000
S91.0 Open wound of ankle	0.001	0.999	0.000
T25.7 Corrosion of third degree of ankle and foot	0.001	0.999	0.000
T25.6 Corrosion of second degree of ankle and foot	0.001	0.999	0.000
T25.5 Corrosion of first degree of ankle and foot	0.001	0.999	0.000
T25.4 Corrosion of unspecified degree of ankle and foot	0.001	0.999	0.000
T25.1 Burn of first degree of ankle and foot	0.001	0.999	0.000
S98 Traumatic amputation of ankle and foot	0.001	0.999	0.000
S95 Injury of blood vessels at ankle and foot level	0.001	0.999	0.000
S94 Injury of nerves at ankle and foot level	0.001	0.999	0.000
H54.0 Blindness, both eyes	0.001	0.999	0.000
Q17.5 Prominent ear	0.001	0.999	0.000
S91.2 Open wound of toe(s) with damage to nail	0.001	0.999	0.000
T25.3 Burn of third degree of ankle and foot	0.001	0.999	0.000
H93 Other disorders of ear, not elsewhere classified	0.000	0.999	0.001
D68.2 Hereditary deficiency of other clotting factors	0.000	0.999	0.001
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.000	0.999	0.001
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.000	0.999	0.001
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.000	0.999	0.001
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.000	0.999	0.001
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.000	0.999	0.001
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.000	0.999	0.001
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
S91.1 Open wound of toe(s) without damage to nail	0.001	0.999	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.001	0.999	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.001	0.999	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.001	0.999	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.001	0.999	0.000
G58 Other mononeuropathies	0.000	0.999	0.001
M25.43 Effusion of joint (Forearm)	0.000	0.999	0.001
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.001	0.999	0.000
G47.9 Sleep disorder, unspecified	0.001	0.999	0.000
J93.1 Other spontaneous pneumothorax	0.000	0.999	0.001
N94.1 Dyspareunia	0.001	0.999	0.000
S92.5 Fracture of other toe	0.001	0.999	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.001	0.999	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.999	0.001
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.001	0.999	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.000	0.999	0.001
N14.3 Nephropathy induced by heavy metals	0.000	0.999	0.001
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.000	0.999	0.001
N14.0 Analgesic nephropathy	0.000	0.999	0.001
N15.8 Other specified renal tubulo-interstitial diseases	0.000	0.999	0.001
N15.0 Balkan nephropathy	0.000	0.999	0.001
S91.7 Multiple open wounds of ankle and foot	0.001	0.999	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.001	0.999	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.001	0.999	0.000
S99 Other and unspecified injuries of ankle and foot	0.001	0.999	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.000	0.999	0.001
N15.1 Renal and perinephric abscess	0.000	0.999	0.001
N87.9 Dysplasia of cervix uteri, unspecified	0.000	0.999	0.001
T78.8 Other adverse effects, not elsewhere classified	0.001	0.999	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.000	0.999	0.001
T78 Adverse effects, not elsewhere classified	0.001	0.999	0.000
S22.30 Fracture of rib (closed)	0.000	0.999	0.001
B18.1 Chronic viral hepatitis B without delta-agent	0.001	0.999	0.000
S92.9 Fracture of foot, unspecified	0.001	0.999	0.000
S92.1 Fracture of talus	0.001	0.999	0.000
T78.3 Angioneurotic oedema	0.001	0.999	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.999	0.001
M94.99 Disorder of cartilage, unspecified (Site unspecified)	0.000	0.999	0.001
M94.98 Disorder of cartilage, unspecified (Other)	0.000	0.999	0.001
M94.97 Disorder of cartilage, unspecified (Ankle and foot)	0.000	0.999	0.001
M94.95 Disorder of cartilage, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M94.94 Disorder of cartilage, unspecified (Hand)	0.000	0.999	0.001
M94.93 Disorder of cartilage, unspecified (Forearm)	0.000	0.999	0.001
M94.92 Disorder of cartilage, unspecified (Upper arm)	0.000	0.999	0.001
M94.91 Disorder of cartilage, unspecified (Shoulder region)	0.000	0.999	0.001
M94.90 Disorder of cartilage, unspecified (Multiple sites)	0.000	0.999	0.001
B18.2 Chronic viral hepatitis C	0.001	0.999	0.000
H34.1 Central retinal artery occlusion	0.001	0.999	0.000
K35.8 Acute appendicitis, other and unspecified	0.001	0.999	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.000	0.999	0.001
S92.0 Fracture of calcaneus	0.001	0.999	0.000
S93.0 Dislocation of ankle joint	0.001	0.999	0.000
S97.1 Crushing injury of toe(s)	0.001	0.999	0.000
S97.0 Crushing injury of ankle	0.001	0.999	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.999	0.001
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.999	0.001
S93.4 Sprain and strain of ankle	0.001	0.999	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.001	0.999	0.000
S93.5 Sprain and strain of toe(s)	0.001	0.999	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.001	0.999	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.001	0.999	0.000
S99.8 Other specified injuries of ankle and foot	0.001	0.999	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.001	0.999	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.001	0.999	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.001	0.999	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.001	0.999	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.001	0.999	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.001	0.999	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.001	0.999	0.000
I46.0 Cardiac arrest with successful resuscitation	0.001	0.999	0.000
K90.9 Intestinal malabsorption, unspecified	0.001	0.999	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.000	0.999	0.001
Q43.8 Other specified congenital malformations of intestine	0.001	0.999	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.001	0.999	0.000
S94.8 Injury of other nerves at ankle and foot level	0.001	0.999	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.001	0.999	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.001	0.999	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.001	0.999	0.000
S94.1 Injury of medial plantar nerve	0.001	0.999	0.000
S94.0 Injury of lateral plantar nerve	0.001	0.999	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.001	0.999	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.001	0.999	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.001	0.999	0.000
S95.2 Injury of dorsal vein of foot	0.001	0.999	0.000
S95.1 Injury of plantar artery of foot	0.001	0.999	0.000
S95.0 Injury of dorsal artery of foot	0.001	0.999	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.001	0.999	0.000
S98.3 Traumatic amputation of other parts of foot	0.001	0.999	0.000
S98.2 Traumatic amputation of two or more toes	0.001	0.999	0.000
S98.1 Traumatic amputation of one toe	0.001	0.999	0.000
S98.0 Traumatic amputation of foot at ankle level	0.001	0.999	0.000
T20 Burn and corrosion of head and neck	0.001	0.999	0.000
F84.5 Asperger's syndrome	0.001	0.999	0.000
H93.2 Other abnormal auditory perceptions	0.000	0.999	0.001
H93.0 Degenerative and vascular disorders of ear	0.000	0.999	0.001
M07.3 Other psoriatic arthropathies	0.000	0.999	0.001
S82.4 Fracture of fibula alone	0.001	0.999	0.000
S92.4 Fracture of great toe	0.001	0.999	0.000
S92.41 Fracture of great toe (open)	0.001	0.999	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.001	0.999	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.001	0.999	0.000
S92.7 Multiple fractures of foot	0.001	0.999	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.001	0.999	0.000
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.001	0.999	0.000
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.001	0.999	0.000
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.001	0.999	0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.001	0.999	0.000
T23 Burn and corrosion of wrist and hand	0.001	0.999	0.000
C90.2 Plasmacytoma, extramedullary	0.001	0.999	0.000
H93.3 Disorders of acoustic nerve	0.000	0.999	0.001
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.999	0.001
R85.5 Abnormal microbiological findings	0.000	0.999	0.001
S99.7 Multiple injuries of ankle and foot	0.001	0.999	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.001	0.999	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.999	0.001
S92.11 Fracture of talus (open)	0.001	0.999	0.000
H57.1 Ocular pain	0.001	0.999	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.999	0.001
J93.8 Other pneumothorax	0.000	0.999	0.001
N97.9 Female infertility, unspecified	0.000	0.999	0.001
Q43.1 Hirschsprung's disease	0.001	0.999	0.000
T23.3 Burn of third degree of wrist and hand	0.001	0.999	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.001	0.999	0.000
T78.9 Adverse effect, unspecified	0.001	0.999	0.000
Y83.3 Surgical operation with formation of external stoma	0.000	0.999	0.001
Q27 Other congenital malformations of peripheral vascular system	0.001	0.999	0.000
M41.56 Other secondary scoliosis (Lumbar region)	0.001	0.999	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.001	0.999	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.000	0.999	0.001
S92.01 Fracture of calcaneus (open)	0.001	0.999	0.000
S92.10 Fracture of talus (closed)	0.001	0.999	0.000
S92.91 Fracture of foot, unspecified (open)	0.001	0.999	0.000
S92.90 Fracture of foot, unspecified (closed)	0.001	0.999	0.000
N13.6 Pyonephrosis	0.000	0.999	0.001
S91.3 Open wound of other parts of foot	0.001	0.999	0.000
T20.1 Burn of first degree of head and neck	0.001	0.999	0.000
Q43 Other congenital malformations of intestine	0.001	0.999	0.000
S93.40 Sprain of unspecified ligament of ankle	0.001	0.999	0.000
H33.3 Retinal breaks without detachment	0.001	0.999	0.000
H93.9 Disorder of ear, unspecified	0.000	0.999	0.001
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.999	0.001
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.999	0.001
I51 Complications and ill-defined descriptions of heart disease	0.000	0.999	0.001
M14 Arthropathies in other diseases classified elsewhere	0.001	0.999	0.000
M07.38 Other psoriatic arthropathies (Other)	0.000	0.999	0.001
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.999	0.001
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.999	0.001
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.999	0.001
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.999	0.001
S92.00 Fracture of calcaneus (closed)	0.001	0.999	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.001	0.999	0.000
D84.9 Immunodeficiency, unspecified	0.001	0.999	0.000
M14.2 Diabetic arthropathy	0.001	0.999	0.000
S20.3 Other superficial injuries of front wall of thorax	0.000	0.999	0.001
T20.7 Corrosion of third degree of head and neck	0.001	0.999	0.000
T20.6 Corrosion of second degree of head and neck	0.001	0.999	0.000
T20.5 Corrosion of first degree of head and neck	0.001	0.999	0.000
T20.4 Corrosion of unspecified degree of head and neck	0.001	0.999	0.000
T20.3 Burn of third degree of head and neck	0.001	0.999	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.001	0.999	0.000
B18 Chronic viral hepatitis	0.001	0.999	0.000
S82.41 Fracture of fibula alone (open)	0.001	0.999	0.000
S92.71 Multiple fractures of foot (open)	0.001	0.999	0.000
D86.9 Sarcoidosis, unspecified	0.001	0.999	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.001	0.999	0.000
N92.4 Excessive bleeding in the premenopausal period	0.001	0.999	0.000
T20.0 Burn of unspecified degree of head and neck	0.001	0.999	0.000
T23.7 Corrosion of third degree of wrist and hand	0.001	0.999	0.000
T23.6 Corrosion of second degree of wrist and hand	0.001	0.999	0.000
T23.5 Corrosion of first degree of wrist and hand	0.001	0.999	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.001	0.999	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.999	0.001
F34.1 Dysthymia	0.001	0.999	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.001	0.999	0.000
H59.0 Vitreous syndrome following cataract surgery	0.001	0.999	0.000
I67.2 Cerebral atherosclerosis	0.000	0.999	0.001
Q79.0 Congenital diaphragmatic hernia	0.001	0.999	0.000
Z13.1 Special screening examination for diabetes mellitus	0.001	0.999	0.000
Z29.2 Other prophylactic chemotherapy	0.000	0.999	0.001
N02 Recurrent and persistent haematuria	0.000	0.999	0.001
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.000	0.999	0.001
I51.0 Cardiac septal defect, acquired	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations