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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12291668
log Bayes Factor = 26.6909
Chromosome 11   position 4,171,345  (GRCh37) Explore rs12291668 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.997 0.003 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.997 0.003 0.000
Chapter V Mental and behavioural disorders
0.996 0.004 0.000
Z72 Problems related to lifestyle
0.995 0.005 0.000
Chapter XIV Diseases of the genitourinary system
0.995 0.005 0.000
R50-R69 General symptoms and signs
0.994 0.006 0.000
Chapter XX External causes of morbidity and mortality
0.994 0.006 0.000
Chapter II Neoplasms
0.994 0.006 0.000
M70-M79 Other soft tissue disorders
0.989 0.011 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.987 0.013 0.000
Chapter I Certain infectious and parasitic diseases
0.986 0.014 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.981 0.019 0.000
S00-S09 Injuries to the head
0.979 0.021 0.000
N17-N19 Renal failure
0.977 0.023 0.000
M20-M25 Other joint disorders
0.975 0.025 0.000
Z72.0 Tobacco use
0.974 0.026 0.000
Z72.1 Alcohol use
0.974 0.026 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.973 0.027 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.972 0.028 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.967 0.033 0.000
N40-N51 Diseases of male genital organs
0.966 0.034 0.000
Chapter VII Diseases of the eye and adnexa
0.963 0.037 0.000
M80-M85 Disorders of bone density and structure
0.963 0.037 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.959 0.041 0.000
R56 Convulsions, not elsewhere classified
0.958 0.042 0.000
R63 Symptoms and signs concerning food and fluid intake
0.957 0.043 0.000
Z02 Examination and encounter for administrative purposes
0.956 0.044 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.953 0.047 0.000
M25 Other joint disorders, not elsewhere classified
0.951 0.049 0.000
M05-M14 Inflammatory polyarthropathies
0.948 0.052 0.000
J09-J18 Influenza and pneumonia
0.946 0.054 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.946 0.054 0.000
B95-B98 Bacterial, viral and other infectious agents
0.946 0.054 0.000
M79.6 Pain in limb
0.945 0.055 0.000
Z02.8 Other examinations for administrative purposes
0.945 0.055 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.941 0.059 0.000
S01 Open wound of head
0.939 0.061 0.000
M79.8 Other specified soft tissue disorders
0.939 0.061 0.000
J90-J94 Other diseases of pleura
0.935 0.065 0.000
R56.8 Other and unspecified convulsions
0.933 0.067 0.000
Z47 Other orthopaedic follow-up care
0.932 0.068 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.930 0.070 0.000
M81 Osteoporosis without pathological fracture
0.929 0.071 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.928 0.072 0.000
R63.4 Abnormal weight loss
0.927 0.073 0.000
M79.66 Pain in limb (Lower leg)
0.924 0.076 0.000
N19 Unspecified renal failure
0.922 0.078 0.000
W00-W19 Falls
0.920 0.080 0.000
E65-E68 Obesity and other hyperalimentation
0.919 0.081 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.914 0.086 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.913 0.087 0.000
F41 Other anxiety disorders
0.912 0.088 0.000
Chapter IX Diseases of the circulatory system
0.912 0.088 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.911 0.089 0.000
J18 Pneumonia, organism unspecified
0.910 0.090 0.000
C15-C26 Malignant neoplasms of digestive organs
0.908 0.092 0.000
M25.5 Pain in joint
0.908 0.092 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.907 0.093 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.907 0.093 0.000
S80-S89 Injuries to the knee and lower leg
0.906 0.094 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.906 0.094 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.902 0.098 0.000
B25-B34 Other viral diseases
0.902 0.098 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.900 0.100 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.899 0.101 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.899 0.101 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.896 0.104 0.000
M81.9 Osteoporosis, unspecified
0.895 0.105 0.000
Z13 Special screening examination for other diseases and disorders
0.892 0.108 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.892 0.108 0.000
R06 Abnormalities of breathing
0.891 0.109 0.000
E70-E90 Metabolic disorders
0.889 0.111 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.888 0.112 0.000
T81 Complications of procedures, not elsewhere classified
0.886 0.114 0.000
F41.9 Anxiety disorder, unspecified
0.885 0.115 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.883 0.117 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.882 0.118 0.000
H04 Disorders of lachrymal system
0.882 0.118 0.000
N25-N29 Other disorders of kidney and ureter
0.881 0.119 0.000
M06 Other rheumatoid arthritis
0.880 0.120 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.879 0.121 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.878 0.122 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.878 0.122 0.000
Z01.8 Other specified special examinations
0.876 0.124 0.000
S70-S79 Injuries to the hip and thigh
0.872 0.128 0.000
E20-E35 Disorders of other endocrine glands
0.872 0.128 0.000
Z45 Adjustment and management of implanted device
0.871 0.129 0.000
J18.1 Lobar pneumonia, unspecified
0.871 0.129 0.000
R55 Syncope and collapse
0.870 0.130 0.000
E66 Obesity
0.870 0.130 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.865 0.135 0.000
M65-M68 Disorders of synovium and tendon
0.861 0.139 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.859 0.141 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.858 0.142 0.000
N17 Acute renal failure
0.855 0.145 0.000
J20-J22 Other acute lower respiratory infections
0.855 0.145 0.000
I30-I52 Other forms of heart disease
0.855 0.145 0.000
R52 Pain, not elsewhere classified
0.854 0.146 0.000
J40-J47 Chronic lower respiratory diseases
0.853 0.147 0.000
R06.0 Dyspnoea
0.851 0.149 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.849 0.151 0.000
C34 Malignant neoplasm of bronchus and lung
0.844 0.156 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.842 0.158 0.000
B34 Viral infection of unspecified site
0.842 0.158 0.000
I73 Other peripheral vascular diseases
0.837 0.163 0.000
C15 Malignant neoplasm of oesophagus
0.835 0.165 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.832 0.168 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.832 0.168 0.000
S00 Superficial injury of head
0.832 0.168 0.000
N43 Hydrocele and spermatocele
0.831 0.169 0.000
N18 Chronic renal failure
0.830 0.170 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.828 0.172 0.000
N48 Other disorders of penis
0.826 0.174 0.000
M06.9 Rheumatoid arthritis, unspecified
0.825 0.175 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.825 0.175 0.000
H02 Other disorders of eyelid
0.824 0.176 0.000
N41 Inflammatory diseases of prostate
0.823 0.177 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.823 0.177 0.000
W19 Unspecified fall
0.820 0.180 0.000
E66.9 Obesity, unspecified
0.820 0.180 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.819 0.181 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.819 0.181 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.819 0.181 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.818 0.182 0.000
M50-M54 Other dorsopathies
0.818 0.182 0.000
R05 Cough
0.817 0.183 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.817 0.183 0.000
S01.5 Open wound of lip and oral cavity
0.816 0.184 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.815 0.185 0.000
M23 Internal derangement of knee
0.815 0.185 0.000
Chapter VI Diseases of the nervous system
0.814 0.186 0.000
Z45.8 Adjustment and management of other implanted devices
0.814 0.186 0.000
J44 Other chronic obstructive pulmonary disease
0.813 0.187 0.000
J95-J99 Other diseases of the respiratory system
0.812 0.188 0.000
J90 Pleural effusion, not elsewhere classified
0.811 0.189 0.000
R42 Dizziness and giddiness
0.810 0.190 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.807 0.193 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.807 0.193 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.801 0.199 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.801 0.199 0.000
Chapter XXII Codes for special purposes
0.801 0.199 0.000
R09.1 Pleurisy
0.800 0.200 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.799 0.201 0.000
B34.9 Viral infection, unspecified
0.799 0.201 0.000
M25.7 Osteophyte
0.798 0.202 0.000
R82 Other abnormal findings in urine
0.798 0.202 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.797 0.203 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.796 0.204 0.000
H10-H13 Disorders of conjunctiva
0.796 0.204 0.000
D50-D53 Nutritional anaemias
0.796 0.204 0.000
H43-H45 Disorders of vitreous body and globe
0.794 0.206 0.000
T51 Toxic effect of alcohol
0.792 0.208 0.000
S60-S69 Injuries to the wrist and hand
0.792 0.208 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.791 0.209 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.791 0.209 0.000
S80 Superficial injury of lower leg
0.790 0.210 0.000
T39.1 4-Aminophenol derivatives
0.789 0.211 0.000
N40 Hyperplasia of prostate
0.789 0.211 0.000
S06 Intracranial injury
0.789 0.211 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.788 0.212 0.000
I49 Other cardiac arrhythmias
0.788 0.212 0.000
R53 Malaise and fatigue
0.787 0.213 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.787 0.213 0.000
S02 Fracture of skull and facial bones
0.787 0.213 0.000
W20-W49 Exposure to inanimate mechanical forces
0.785 0.215 0.000
F30-F39 Mood [affective] disorders
0.785 0.215 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.785 0.215 0.000
H00 Hordeolum and chalazion
0.784 0.216 0.000
M25.56 Pain in joint (Lower leg)
0.784 0.216 0.000
M25.51 Pain in joint (Shoulder region)
0.784 0.216 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.783 0.217 0.000
Z13.9 Special screening examination, unspecified
0.783 0.217 0.000
M10 Gout
0.782 0.218 0.000
E50-E64 Other nutritional deficiencies
0.781 0.219 0.000
N30-N39 Other diseases of urinary system
0.781 0.219 0.000
M34 Systemic sclerosis
0.779 0.221 0.000
F43 Reaction to severe stress, and adjustment disorders
0.778 0.222 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.777 0.223 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.777 0.223 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.776 0.224 0.000
Z51 Other medical care
0.776 0.224 0.000
S01.8 Open wound of other parts of head
0.775 0.225 0.000
R61 Hyperhidrosis
0.774 0.226 0.000
F60-F69 Disorders of adult personality and behaviour
0.772 0.228 0.000
E00-E07 Disorders of thyroid gland
0.772 0.228 0.000
S82 Fracture of lower leg, including ankle
0.770 0.230 0.000
Z48 Other surgical follow-up care
0.769 0.230 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.768 0.232 0.000
N17.9 Acute renal failure, unspecified
0.768 0.232 0.000
C79 Secondary malignant neoplasm of other sites
0.768 0.232 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.767 0.233 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.766 0.234 0.000
F99-F99 Unspecified mental disorder
0.766 0.234 0.000
M31 Other necrotising vasculopathies
0.766 0.234 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.766 0.234 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.765 0.235 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.765 0.235 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.765 0.235 0.000
I74 Arterial embolism and thrombosis
0.765 0.235 0.000
M81.98 Osteoporosis, unspecified (Other)
0.763 0.237 0.000
M25.57 Pain in joint (Ankle and foot)
0.762 0.238 0.000
D10-D36 Benign neoplasms
0.762 0.238 0.000
S20-S29 Injuries to the thorax
0.761 0.239 0.000
J94 Other pleural conditions
0.760 0.240 0.000
I73.9 Peripheral vascular disease, unspecified
0.760 0.240 0.000
M65 Synovitis and tenosynovitis
0.759 0.240 0.000
M25.9 Joint disorder, unspecified
0.758 0.242 0.000
Y84.2 Radiological procedure and radiotherapy
0.758 0.242 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.758 0.242 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.757 0.243 0.000
J86 Pyothorax
0.757 0.243 0.000
F10.0 Acute intoxication
0.757 0.243 0.000
S01.0 Open wound of scalp
0.757 0.243 0.000
M05 Seropositive rheumatoid arthritis
0.757 0.243 0.000
J81 Pulmonary oedema
0.756 0.244 0.000
M45-M49 Spondylopathies
0.755 0.245 0.000
F10.1 Harmful use
0.754 0.246 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.754 0.246 0.000
J22 Unspecified acute lower respiratory infection
0.753 0.247 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.753 0.247 0.000
H02.3 Blepharochalasis
0.753 0.247 0.000
C34.9 Bronchus or lung, unspecified
0.753 0.247 0.000
M25.8 Other specified joint disorders
0.751 0.249 0.000
Z42 Follow-up care involving plastic surgery
0.751 0.249 0.000
Z54 Convalescence
0.751 0.249 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.750 0.249 0.000
J18.9 Pneumonia, unspecified
0.750 0.250 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.748 0.251 0.000
W08 Fall involving other furniture
0.748 0.252 0.000
Z75 Problems related to medical facilities and other health care
0.748 0.252 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.748 0.252 0.000
M40-M43 Deforming dorsopathies
0.748 0.252 0.000
S90-S99 Injuries to the ankle and foot
0.747 0.253 0.000
N45 Orchitis and epididymitis
0.747 0.253 0.000
A80-A89 Viral infections of the central nervous system
0.747 0.253 0.000
Y57 Other and unspecified drugs and medicaments
0.747 0.253 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.746 0.253 0.000
I73.0 Raynaud's syndrome
0.746 0.254 0.000
J92 Pleural plaque
0.746 0.254 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.746 0.254 0.000
T66-T78 Other and unspecified effects of external causes
0.745 0.255 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.744 0.256 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.744 0.256 0.000
M81.4 Drug-induced osteoporosis
0.744 0.256 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.743 0.257 0.000
Z04 Examination and observation for other reasons
0.742 0.258 0.000
M07 Psoriatic and enteropathic arthropathies
0.742 0.258 0.000
G40-G47 Episodic and paroxysmal disorders
0.741 0.259 0.000
D51 Vitamin B12 deficiency anaemia
0.740 0.259 0.000
J84 Other interstitial pulmonary diseases
0.740 0.260 0.000
S01.9 Open wound of head, part unspecified
0.740 0.260 0.000
R79 Other abnormal findings of blood chemistry
0.739 0.261 0.000
M71 Other bursopathies
0.738 0.262 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.736 0.264 0.000
N00-N08 Glomerular diseases
0.736 0.264 0.000
S70 Superficial injury of hip and thigh
0.734 0.266 0.000
N43.3 Hydrocele, unspecified
0.734 0.266 0.000
R73 Elevated blood glucose level
0.733 0.267 0.000
M84 Disorders of continuity of bone
0.732 0.268 0.000
W19.9 Unspecified place
0.732 0.268 0.000
T79-T79 Certain early complications of trauma
0.732 0.268 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.731 0.269 0.000
T63 Toxic effect of contact with venomous animals
0.730 0.270 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.730 0.270 0.000
R68 Other general symptoms and signs
0.729 0.271 0.000
R52.1 Chronic intractable pain
0.729 0.271 0.000
M22 Disorders of patella
0.729 0.271 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.728 0.272 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.728 0.272 0.000
S50-S59 Injuries to the elbow and forearm
0.728 0.272 0.000
E22 Hyperfunction of pituitary gland
0.728 0.272 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.728 0.272 0.000
M77 Other enthesopathies
0.727 0.273 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.727 0.273 0.000
R82.9 Other and unspecified abnormal finding in urine
0.726 0.274 0.000
F45 Somatoform disorders
0.726 0.274 0.000
J93 Pneumothorax
0.725 0.275 0.000
H55-H59 Other disorders of eye and adnexa
0.725 0.275 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.725 0.275 0.000
R06.6 Hiccough
0.724 0.275 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.724 0.275 0.000
N18.3 Chronic kidney disease, stage 3
0.723 0.277 0.000
S01.3 Open wound of ear
0.721 0.278 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.721 0.279 0.000
C60-C63 Malignant neoplasms of male genital organs
0.720 0.280 0.000
B35-B49 Mycoses
0.718 0.282 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.718 0.282 0.000
C80 Malignant neoplasm without specification of site
0.718 0.282 0.000
R80 Isolated proteinuria
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M86-M90 Other osteopathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
I49.8 Other specified cardiac arrhythmias
0.717 0.283 0.000
S40-S49 Injuries to the shoulder and upper arm
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Z76 Persons encountering health services in other circumstances
0.715 0.285 0.000
Z73 Problems related to life-management difficulty
0.715 0.285 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.715 0.285 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.715 0.285 0.000
Z74 Problems related to care-provider dependency
0.715 0.285 0.000
T87 Complications peculiar to reattachment and amputation
0.715 0.285 0.000
T86 Failure and rejection of transplanted organs and tissues
0.715 0.285 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.715 0.285 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.715 0.285 0.000
R76 Other abnormal immunological findings in serum
0.714 0.286 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.714 0.286 0.000
F80-F89 Disorders of psychological development
0.714 0.286 0.000
F70-F79 Mental retardation
0.714 0.286 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.714 0.286 0.000
Z72.9 Problem related to lifestyle, unspecified
0.713 0.286 0.000
Z72.8 Other problems related to lifestyle
0.713 0.286 0.000
Z72.6 Gambling and betting
0.713 0.286 0.000
Z72.5 High-risk sexual behaviour
0.713 0.286 0.000
Z72.4 Inappropriate diet and eating habits
0.713 0.286 0.000
Z72.3 Lack of physical exercise
0.713 0.286 0.000
Z72.2 Drug use
0.713 0.286 0.000
M79.0 Rheumatism, unspecified
0.713 0.287 0.000
D27 Benign neoplasm of ovary
0.713 0.287 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.713 0.287 0.000
R62 Lack of expected normal physiological development
0.713 0.287 0.000
R57 Shock, not elsewhere classified
0.713 0.287 0.000
R64 Cachexia
0.713 0.287 0.000
R58 Haemorrhage, not elsewhere classified
0.713 0.287 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.713 0.287 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.287 0.000
Y10-Y34 Event of undetermined intent
0.713 0.287 0.000
Y00-Y09 Assault
0.713 0.287 0.000
X85-X99 Assault
0.713 0.287 0.000
X60-X84 Intentional self-harm
0.713 0.287 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.713 0.287 0.000
X50-X57 Overexertion, travel and privation
0.713 0.287 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.713 0.287 0.000
X30-X39 Exposure to forces of nature
0.713 0.287 0.000
X20-X29 Contact with venomous animals and plants
0.713 0.287 0.000
X10-X19 Contact with heat and hot substances
0.713 0.287 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.287 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.287 0.000
W75-W84 Other accidental threats to breathing
0.713 0.287 0.000
W65-W74 Accidental drowning and submersion
0.713 0.287 0.000
W50-W64 Exposure to animate mechanical forces
0.713 0.287 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.287 0.000
V95-V97 Air and space transport accidents
0.713 0.287 0.000
V90-V94 Water transport accidents
0.713 0.287 0.000
V80-V89 Other land transport accidents
0.713 0.287 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.287 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.287 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.287 0.000
V40-V49 Car occupant injured in transport accident
0.713 0.287 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.287 0.000
V20-V29 Motorcycle rider injured in transport accident
0.713 0.287 0.000
V10-V19 Pedal cyclist injured in transport accident
0.713 0.287 0.000
V01-V09 Pedestrian injured in transport accident
0.713 0.287 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.713 0.287 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.713 0.287 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.713 0.287 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.713 0.287 0.000
Z43 Attention to artificial openings
0.713 0.287 0.000
R45 Symptoms and signs involving emotional state
0.713 0.287 0.000
H04.2 Epiphora
0.712 0.288 0.000
R69 Unknown and unspecified causes of morbidity
0.712 0.288 0.000
D80-D89 Certain disorders involving the immune mechanism
0.711 0.289 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.711 0.289 0.000
M76 Enthesopathies of lower limb, excluding foot
0.709 0.291 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.709 0.291 0.000
W07 Fall involving chair
0.709 0.291 0.000
C15.9 Oesophagus, unspecified
0.708 0.292 0.000
E40-E46 Malnutrition
0.708 0.292 0.000
S72 Fracture of femur
0.708 0.292 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.707 0.292 0.000
C20 Malignant neoplasm of rectum
0.707 0.293 0.000
C15.4 Middle third of oesophagus
0.707 0.293 0.000
C77.0 Lymph nodes of head, face and neck
0.707 0.293 0.000
B99-B99 Other infectious diseases
0.707 0.293 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.707 0.293 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.707 0.293 0.000
B65-B83 Helminthiases
0.707 0.293 0.000
B50-B64 Protozoal diseases
0.707 0.293 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.707 0.293 0.000
B15-B19 Viral hepatitis
0.707 0.293 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.707 0.293 0.000
A75-A79 Rickettsioses
0.707 0.293 0.000
A70-A74 Other diseases caused by chlamydiae
0.707 0.293 0.000
A65-A69 Other spirochaetal diseases
0.707 0.293 0.000
A20-A28 Certain zoonotic bacterial diseases
0.707 0.293 0.000
A15-A19 Tuberculosis
0.707 0.293 0.000
M80 Osteoporosis with pathological fracture
0.706 0.294 0.000
M54 Dorsalgia
0.706 0.294 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.705 0.294 0.000
M79.9 Soft tissue disorder, unspecified
0.703 0.297 0.000
M79.5 Residual foreign body in soft tissue
0.703 0.297 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.703 0.297 0.000
M79.3 Panniculitis, unspecified
0.703 0.297 0.000
M79.2 Neuralgia and neuritis, unspecified
0.703 0.297 0.000
M79.1 Myalgia
0.703 0.297 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.703 0.297 0.000
E87.2 Acidosis
0.703 0.297 0.000
Y86 Sequelae of other accidents
0.703 0.297 0.000
S01.1 Open wound of eyelid and periocular area
0.702 0.298 0.000
S08 Traumatic amputation of part of head
0.702 0.298 0.000
S07 Crushing injury of head
0.702 0.298 0.000
S05 Injury of eye and orbit
0.702 0.298 0.000
S04 Injury of cranial nerves
0.702 0.298 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.702 0.298 0.000
R47-R49 Symptoms and signs involving speech and voice
0.701 0.299 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.701 0.299 0.000
R63.0 Anorexia
0.700 0.299 0.000
C51-C58 Malignant neoplasms of female genital organs
0.700 0.300 0.000
F10.2 Dependence syndrome
0.700 0.300 0.000
M72 Fibroblastic disorders
0.700 0.300 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.700 0.300 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.699 0.301 0.000
M33 Dermatopolymyositis
0.699 0.301 0.000
M32 Systemic lupus erythematosus
0.699 0.301 0.000
M30 Polyarteritis nodosa and related conditions
0.699 0.301 0.000
M24 Other specific joint derangements
0.699 0.301 0.000
M21 Other acquired deformities of limbs
0.699 0.301 0.000
S80.8 Other superficial injuries of lower leg
0.699 0.301 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.698 0.302 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.698 0.302 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.697 0.303 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.697 0.303 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.697 0.303 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.697 0.303 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.697 0.303 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.697 0.303 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.697 0.303 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.697 0.303 0.000
T36 Poisoning by systemic antibiotics
0.697 0.303 0.000
N28.8 Other specified disorders of kidney and ureter
0.697 0.303 0.000
N48.8 Other specified disorders of penis
0.697 0.303 0.000
Z10 Routine general health check-up of defined subpopulation
0.697 0.303 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.697 0.303 0.000
E66.8 Other obesity
0.697 0.303 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.696 0.304 0.000
N42 Other disorders of prostate
0.695 0.305 0.000
N41.1 Chronic prostatitis
0.694 0.306 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.694 0.306 0.000
Z52 Donors of organs and tissues
0.693 0.307 0.000
Z49 Care involving dialysis
0.693 0.307 0.000
Z44 Fitting and adjustment of external prosthetic device
0.693 0.307 0.000
Y52 Agents primarily affecting the cardiovascular system
0.693 0.307 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.692 0.308 0.000
N46 Male infertility
0.692 0.308 0.000
N44 Torsion of testis
0.692 0.308 0.000
M23.3 Other meniscus derangements
0.692 0.308 0.000
I46 Cardiac arrest
0.691 0.309 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.691 0.309 0.000
N20-N23 Urolithiasis
0.691 0.309 0.000
Y44 Agents primarily affecting blood constituents
0.691 0.309 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.690 0.310 0.000
M85 Other disorders of bone density and structure
0.690 0.310 0.000
M83 Adult osteomalacia
0.690 0.310 0.000
M82 Osteoporosis in diseases classified elsewhere
0.690 0.310 0.000
F41.2 Mixed anxiety and depressive disorder
0.689 0.311 0.000
M25.50 Pain in joint (Multiple sites)
0.689 0.311 0.000
I51 Complications and ill-defined descriptions of heart disease
0.688 0.312 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.688 0.312 0.000
F48 Other neurotic disorders
0.687 0.313 0.000
F44 Dissociative [conversion] disorders
0.687 0.313 0.000
F42 Obsessive-compulsive disorder
0.687 0.313 0.000
R56.0 Febrile convulsions
0.687 0.313 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.687 0.313 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.687 0.313 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.686 0.314 0.000
R63.5 Abnormal weight gain
0.686 0.314 0.000
R63.3 Feeding difficulties and mismanagement
0.686 0.314 0.000
R63.2 Polyphagia
0.686 0.314 0.000
R63.1 Polydipsia
0.686 0.314 0.000
J86.9 Pyothorax without fistula
0.685 0.314 0.000
Z02.9 Examination for administrative purposes, unspecified
0.685 0.314 0.000
Z02.7 Issue of medical certificate
0.685 0.314 0.000
Z02.6 Examination for insurance purposes
0.685 0.314 0.000
Z02.5 Examination for participation in sport
0.685 0.314 0.000
Z02.4 Examination for driving licence
0.685 0.314 0.000
Z02.3 Examination for recruitment to armed forces
0.685 0.314 0.000
Z02.2 Examination for admission to residential institution
0.685 0.314 0.000
Z02.1 Pre-employment examination
0.685 0.314 0.000
Z02.0 Examination for admission to educational institution
0.685 0.314 0.000
M79.60 Pain in limb (Multiple sites)
0.685 0.315 0.000
A00-A09 Intestinal infectious diseases
0.685 0.315 0.000
C77.1 Intrathoracic lymph nodes
0.685 0.315 0.000
R20 Disturbances of skin sensation
0.685 0.315 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.683 0.317 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.683 0.317 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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