TreeWAS – Variant ID: rs1229542

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N93.8 Other specified abnormal uterine and vaginal bleeding	0.000	0.973	0.027
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.000	0.979	0.021
F10.1 Harmful use	0.000	0.984	0.016
F10.3 Withdrawal state	0.000	0.985	0.015
F10 Mental and behavioural disorders due to use of alcohol	0.000	0.985	0.015
F10.4 Withdrawal state with delirium	0.000	0.988	0.012
F10.2 Dependence syndrome	0.000	0.989	0.011
D05.1 Intraductal carcinoma in situ	0.011	0.989	0.000
F10.9 Unspecified mental and behavioural disorder	0.000	0.989	0.011
F10.8 Other mental and behavioural disorders	0.000	0.989	0.011
F10.7 Residual and late-onset psychotic disorder	0.000	0.989	0.011
F10.6 Amnesic syndrome	0.000	0.989	0.011
F10.0 Acute intoxication	0.000	0.990	0.010
D05.9 Carcinoma in situ of breast, unspecified	0.010	0.990	0.000
F10.5 Psychotic disorder	0.000	0.990	0.010
D05 Carcinoma in situ of breast	0.010	0.990	0.000
D05.7 Other carcinoma in situ of breast	0.007	0.993	0.000
O72.1 Other immediate postpartum haemorrhage	0.000	0.993	0.007
N93 Other abnormal uterine and vaginal bleeding	0.000	0.993	0.007
N43.3 Hydrocele, unspecified	0.000	0.993	0.007
D05.0 Lobular carcinoma in situ	0.006	0.994	0.000
N93.0 Postcoital and contact bleeding	0.000	0.994	0.006
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.000	0.994	0.006
R09.1 Pleurisy	0.000	0.995	0.005
F20.9 Schizophrenia, unspecified	0.000	0.995	0.005
S90 Superficial injury of ankle and foot	0.005	0.995	0.000
S90.8 Other superficial injuries of ankle and foot	0.005	0.995	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.000	0.995	0.005
C44.1 Skin of eyelid, including canthus	0.000	0.995	0.005
S90.9 Superficial injury of ankle and foot, unspecified	0.004	0.996	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.000	0.996	0.004
S90.0 Contusion of ankle	0.004	0.996	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.000	0.996	0.004
F18 Mental and behavioural disorders due to use of volatile solvents	0.000	0.996	0.004
F16 Mental and behavioural disorders due to use of hallucinogens	0.000	0.996	0.004
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.000	0.996	0.004
F14 Mental and behavioural disorders due to use of cocaine	0.000	0.996	0.004
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.000	0.996	0.004
F11 Mental and behavioural disorders due to use of opioids	0.000	0.996	0.004
S90.1 Contusion of toe(s) without damage to nail	0.004	0.996	0.000
F20 Schizophrenia	0.000	0.996	0.004
D00-D09 In situ neoplasms	0.004	0.996	0.000
Z42.1 Follow-up care involving plastic surgery of breast	0.004	0.996	0.000
T39.1 4-Aminophenol derivatives	0.000	0.996	0.004
D04.3 Skin of other and unspecified parts of face	0.004	0.996	0.000
T40.2 Other opioids	0.000	0.996	0.004
F20.0 Paranoid schizophrenia	0.000	0.996	0.004
S90.7 Multiple superficial injuries of ankle and foot	0.004	0.996	0.000
S90.3 Contusion of other and unspecified parts of foot	0.004	0.996	0.000
S90.2 Contusion of toe(s) with damage to nail	0.004	0.996	0.000
O72 Postpartum haemorrhage	0.000	0.996	0.004
I42.0 Dilated cardiomyopathy	0.000	0.996	0.004
D09 Carcinoma in situ of other and unspecified sites	0.004	0.996	0.000
C44.2 Skin of ear and external auricular canal	0.000	0.996	0.004
D04 Carcinoma in situ of skin	0.003	0.996	0.000
I42.9 Cardiomyopathy, unspecified	0.000	0.996	0.004
D07 Carcinoma in situ of other and unspecified genital organs	0.003	0.997	0.000
F12.1 Harmful use	0.000	0.997	0.003
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.000	0.997	0.003
F12.9 Unspecified mental and behavioural disorder	0.000	0.997	0.003
F12.8 Other mental and behavioural disorders	0.000	0.997	0.003
F12.7 Residual and late-onset psychotic disorder	0.000	0.997	0.003
F12.6 Amnesic syndrome	0.000	0.997	0.003
F12.5 Psychotic disorder	0.000	0.997	0.003
F12.4 Withdrawal state with delirium	0.000	0.997	0.003
F12.3 Withdrawal state	0.000	0.997	0.003
F12.2 Dependence syndrome	0.000	0.997	0.003
F12.0 Acute intoxication	0.000	0.997	0.003
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.003	0.997	0.000
F11.9 Unspecified mental and behavioural disorder	0.000	0.997	0.003
F11.8 Other mental and behavioural disorders	0.000	0.997	0.003
F11.7 Residual and late-onset psychotic disorder	0.000	0.997	0.003
F11.6 Amnesic syndrome	0.000	0.997	0.003
F11.5 Psychotic disorder	0.000	0.997	0.003
F11.4 Withdrawal state with delirium	0.000	0.997	0.003
F11.3 Withdrawal state	0.000	0.997	0.003
F11.2 Dependence syndrome	0.000	0.997	0.003
F11.1 Harmful use	0.000	0.997	0.003
F11.0 Acute intoxication	0.000	0.997	0.003
F13.9 Unspecified mental and behavioural disorder	0.000	0.997	0.003
F13.8 Other mental and behavioural disorders	0.000	0.997	0.003
F13.7 Residual and late-onset psychotic disorder	0.000	0.997	0.003
F13.6 Amnesic syndrome	0.000	0.997	0.003
F13.5 Psychotic disorder	0.000	0.997	0.003
F13.4 Withdrawal state with delirium	0.000	0.997	0.003
F13.3 Withdrawal state	0.000	0.997	0.003
F13.2 Dependence syndrome	0.000	0.997	0.003
F13.1 Harmful use	0.000	0.997	0.003
F13.0 Acute intoxication	0.000	0.997	0.003
F14.9 Unspecified mental and behavioural disorder	0.000	0.997	0.003
F14.8 Other mental and behavioural disorders	0.000	0.997	0.003
F14.7 Residual and late-onset psychotic disorder	0.000	0.997	0.003
F14.6 Amnesic syndrome	0.000	0.997	0.003
F14.5 Psychotic disorder	0.000	0.997	0.003
F14.4 Withdrawal state with delirium	0.000	0.997	0.003
F14.3 Withdrawal state	0.000	0.997	0.003
F14.2 Dependence syndrome	0.000	0.997	0.003
F14.1 Harmful use	0.000	0.997	0.003
F14.0 Acute intoxication	0.000	0.997	0.003
F15.9 Unspecified mental and behavioural disorder	0.000	0.997	0.003
F15.8 Other mental and behavioural disorders	0.000	0.997	0.003
F15.7 Residual and late-onset psychotic disorder	0.000	0.997	0.003
F15.6 Amnesic syndrome	0.000	0.997	0.003
F15.5 Psychotic disorder	0.000	0.997	0.003
F15.4 Withdrawal state with delirium	0.000	0.997	0.003
F15.3 Withdrawal state	0.000	0.997	0.003
F15.2 Dependence syndrome	0.000	0.997	0.003
F15.1 Harmful use	0.000	0.997	0.003
F15.0 Acute intoxication	0.000	0.997	0.003
F16.9 Unspecified mental and behavioural disorder	0.000	0.997	0.003
F16.8 Other mental and behavioural disorders	0.000	0.997	0.003
F16.7 Residual and late-onset psychotic disorder	0.000	0.997	0.003
F16.6 Amnesic syndrome	0.000	0.997	0.003
F16.5 Psychotic disorder	0.000	0.997	0.003
F16.4 Withdrawal state with delirium	0.000	0.997	0.003
F16.3 Withdrawal state	0.000	0.997	0.003
F16.2 Dependence syndrome	0.000	0.997	0.003
F16.1 Harmful use	0.000	0.997	0.003
F16.0 Acute intoxication	0.000	0.997	0.003
F18.9 Unspecified mental and behavioural disorder	0.000	0.997	0.003
F18.8 Other mental and behavioural disorders	0.000	0.997	0.003
F18.7 Residual and late-onset psychotic disorder	0.000	0.997	0.003
F18.6 Amnesic syndrome	0.000	0.997	0.003
F18.5 Psychotic disorder	0.000	0.997	0.003
F18.4 Withdrawal state with delirium	0.000	0.997	0.003
F18.3 Withdrawal state	0.000	0.997	0.003
F18.2 Dependence syndrome	0.000	0.997	0.003
F18.1 Harmful use	0.000	0.997	0.003
F18.0 Acute intoxication	0.000	0.997	0.003
F19.9 Unspecified mental and behavioural disorder	0.000	0.997	0.003
F19.8 Other mental and behavioural disorders	0.000	0.997	0.003
F19.7 Residual and late-onset psychotic disorder	0.000	0.997	0.003
F19.6 Amnesic syndrome	0.000	0.997	0.003
F19.5 Psychotic disorder	0.000	0.997	0.003
F19.4 Withdrawal state with delirium	0.000	0.997	0.003
F19.3 Withdrawal state	0.000	0.997	0.003
F19.2 Dependence syndrome	0.000	0.997	0.003
F19.1 Harmful use	0.000	0.997	0.003
F19.0 Acute intoxication	0.000	0.997	0.003
R09.0 Asphyxia	0.000	0.997	0.003
F20.8 Other schizophrenia	0.000	0.997	0.003
F20.6 Simple schizophrenia	0.000	0.997	0.003
F20.5 Residual schizophrenia	0.000	0.997	0.003
F20.4 Postschizophrenic depression	0.000	0.997	0.003
F20.3 Undifferentiated schizophrenia	0.000	0.997	0.003
F20.2 Catatonic schizophrenia	0.000	0.997	0.003
F20.1 Hebephrenic schizophrenia	0.000	0.997	0.003
D02 Carcinoma in situ of middle ear and respiratory system	0.003	0.997	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.997	0.003
D01 Carcinoma in situ of other and unspecified digestive organs	0.003	0.997	0.000
S32.50 Fracture of pubis (closed)	0.000	0.997	0.003
D07.5 Prostate	0.003	0.997	0.000
D09.0 Bladder	0.003	0.997	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.997	0.003
O72.0 Third-stage haemorrhage	0.000	0.997	0.003
I42 Cardiomyopathy	0.000	0.997	0.003
R09.3 Abnormal sputum	0.000	0.997	0.003
S92.00 Fracture of calcaneus (closed)	0.003	0.997	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.997	0.003
E04.9 Non-toxic goitre, unspecified	0.003	0.997	0.000
T42.4 Benzodiazepines	0.000	0.997	0.003
N43 Hydrocele and spermatocele	0.000	0.997	0.003
S90-S99 Injuries to the ankle and foot	0.003	0.997	0.000
S92.0 Fracture of calcaneus	0.003	0.997	0.000
N18.9 Chronic renal failure, unspecified	0.000	0.997	0.003
O72.3 Postpartum coagulation defects	0.000	0.997	0.003
D09.9 Carcinoma in situ, unspecified	0.003	0.997	0.000
D09.7 Carcinoma in situ of other specified sites	0.003	0.997	0.000
D09.3 Thyroid and other endocrine glands	0.003	0.997	0.000
D09.2 Eye	0.003	0.997	0.000
D09.1 Other and unspecified urinary organs	0.003	0.997	0.000
S92 Fracture of foot, except ankle	0.003	0.997	0.000
Chapter V Mental and behavioural disorders	0.000	0.997	0.003
D06 Carcinoma in situ of cervix uteri	0.003	0.997	0.000
D04.9 Skin, unspecified	0.003	0.997	0.000
D04.8 Skin of other sites	0.003	0.997	0.000
D04.4 Skin of scalp and neck	0.003	0.997	0.000
D04.2 Skin of ear and external auricular canal	0.003	0.997	0.000
D04.1 Skin of eyelid, including canthus	0.003	0.997	0.000
D04.0 Skin of lip	0.003	0.997	0.000
N73.6 Female pelvic peritoneal adhesions	0.000	0.997	0.003
D00.0 Lip, oral cavity and pharynx	0.003	0.997	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.997	0.003
F29 Unspecified nonorganic psychosis	0.000	0.997	0.003
D07.6 Other and unspecified male genital organs	0.003	0.997	0.000
D07.4 Penis	0.003	0.997	0.000
D07.3 Other and unspecified female genital organs	0.003	0.997	0.000
D07.2 Vagina	0.003	0.997	0.000
D07.0 Endometrium	0.003	0.997	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.997	0.003
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.997	0.003
D00.2 Stomach	0.002	0.997	0.000
D00.1 Oesophagus	0.002	0.997	0.000
D02.4 Respiratory system, unspecified	0.002	0.997	0.000
D02.3 Other parts of respiratory system	0.002	0.997	0.000
D02.2 Bronchus and lung	0.002	0.997	0.000
D02.1 Trachea	0.002	0.997	0.000
D02.0 Larynx	0.002	0.997	0.000
R09.2 Respiratory arrest	0.000	0.997	0.003
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.997	0.003
D01.9 Digestive organ, unspecified	0.002	0.997	0.000
D01.7 Other specified digestive organs	0.002	0.997	0.000
D01.5 Liver, gallbladder and bile ducts	0.002	0.997	0.000
D01.4 Other and unspecified parts of intestine	0.002	0.997	0.000
D01.3 Anus and anal canal	0.002	0.997	0.000
D01.2 Rectum	0.002	0.997	0.000
D01.1 Rectosigmoid junction	0.002	0.997	0.000
D01.0 Colon	0.002	0.997	0.000
F28 Other nonorganic psychotic disorders	0.000	0.997	0.002
F24 Induced delusional disorder	0.000	0.997	0.002
F21 Schizotypal disorder	0.000	0.997	0.002
Z42.0 Follow-up care involving plastic surgery of head and neck	0.003	0.997	0.000
Z42 Follow-up care involving plastic surgery	0.003	0.997	0.000
D04.6 Skin of upper limb, including shoulder	0.002	0.997	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.000	0.997	0.002
F25 Schizoaffective disorders	0.000	0.997	0.002
I42.8 Other cardiomyopathies	0.000	0.997	0.002
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.997	0.002
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.997	0.002
T39.4 Antirheumatics, not elsewhere classified	0.000	0.997	0.002
T39.2 Pyrazolone derivatives	0.000	0.997	0.002
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.997	0.002
I42.6 Alcoholic cardiomyopathy	0.000	0.997	0.002
I42.5 Other restrictive cardiomyopathy	0.000	0.997	0.002
I42.4 Endocardial fibroelastosis	0.000	0.997	0.002
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.997	0.002
I42.2 Other hypertrophic cardiomyopathy	0.000	0.997	0.002
O82.0 Delivery by elective Caesarean section	0.000	0.997	0.003
S99 Other and unspecified injuries of ankle and foot	0.002	0.997	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.997	0.000
D04.5 Skin of trunk	0.002	0.997	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.000	0.998	0.002
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.998	0.002
T40.8 Lysergide [LSD]	0.000	0.998	0.002
T40.7 Cannabis (derivatives)	0.000	0.998	0.002
T40.5 Cocaine	0.000	0.998	0.002
T40.3 Methadone	0.000	0.998	0.002
T40.1 Heroin	0.000	0.998	0.002
T40.0 Opium	0.000	0.998	0.002
F22 Persistent delusional disorders	0.000	0.998	0.002
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
N43.4 Spermatocele	0.000	0.998	0.002
N43.2 Other hydrocele	0.000	0.998	0.002
N43.1 Infected hydrocele	0.000	0.998	0.002
N43.0 Encysted hydrocele	0.000	0.998	0.002
S92.5 Fracture of other toe	0.002	0.998	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.000	0.998	0.002
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
F60-F69 Disorders of adult personality and behaviour	0.000	0.998	0.002
T40.4 Other synthetic narcotics	0.000	0.998	0.002
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
D07.1 Vulva	0.002	0.998	0.000
S92.01 Fracture of calcaneus (open)	0.002	0.998	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.998	0.002
F41.2 Mixed anxiety and depressive disorder	0.000	0.998	0.002
F23 Acute and transient psychotic disorders	0.000	0.998	0.002
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.998	0.002
N18.5 Chronic kidney disease, stage 5	0.000	0.998	0.002
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.000	0.998	0.002
F70-F79 Mental retardation	0.000	0.998	0.002
D04.7 Skin of lower limb, including hip	0.002	0.998	0.000
D06.7 Other parts of cervix	0.002	0.998	0.000
D06.1 Exocervix	0.002	0.998	0.000
D06.0 Endocervix	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.002	0.998	0.000
S92.4 Fracture of great toe	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
F33 Recurrent depressive disorder	0.000	0.998	0.002
T39.0 Salicylates	0.000	0.998	0.002
F42.9 Obsessive-compulsive disorder, unspecified	0.000	0.998	0.002
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.998	0.002
N18.4 Chronic kidney disease, stage 4	0.000	0.998	0.002
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
F99-F99 Unspecified mental disorder	0.000	0.998	0.002
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.002	0.998	0.000
D03 Melanoma in situ	0.002	0.998	0.000
S92.1 Fracture of talus	0.002	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.998	0.002
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.002
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.998	0.002
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.998	0.002
T36 Poisoning by systemic antibiotics	0.000	0.998	0.002
T43.2 Other and unspecified antidepressants	0.000	0.998	0.002
S92.3 Fracture of metatarsal bone	0.002	0.998	0.000
S99.9 Unspecified injury of ankle and foot	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.998	0.002
T40.6 Other and unspecified narcotics	0.000	0.998	0.002
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.000	0.998	0.002
F42 Obsessive-compulsive disorder	0.000	0.998	0.002
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.998	0.002
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.998	0.002
T42.3 Barbiturates	0.000	0.998	0.002
T42.2 Succinimides and oxazolidinediones	0.000	0.998	0.002
T42.1 Iminostilbenes	0.000	0.998	0.002
T42.0 Hydantoin derivatives	0.000	0.998	0.002
T43.9 Psychotropic drug, unspecified	0.000	0.998	0.002
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
T43.6 Psychostimulants with abuse potential	0.000	0.998	0.002
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.998	0.002
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.998	0.002
F60 Specific personality disorders	0.000	0.998	0.002
S91 Open wound of ankle and foot	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.998	0.002
F40-F48 Neurotic, stress-related and somatoform disorders	0.000	0.998	0.002
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
Z42.9 Follow-up care involving plastic surgery, unspecified	0.002	0.998	0.000
Z42.8 Follow-up care involving plastic surgery of other body part	0.002	0.998	0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.002	0.998	0.000
F25.8 Other schizoaffective disorders	0.000	0.998	0.002
F25.2 Schizoaffective disorder, mixed type	0.000	0.998	0.002
F25.1 Schizoaffective disorder, depressive type	0.000	0.998	0.002
F25.0 Schizoaffective disorder, manic type	0.000	0.998	0.002
N18 Chronic renal failure	0.000	0.998	0.002
D03.6 Melanoma in situ of upper limb, including shoulder	0.002	0.998	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.998	0.002
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
S99.8 Other specified injuries of ankle and foot	0.002	0.998	0.000
S99.7 Multiple injuries of ankle and foot	0.002	0.998	0.000
F30-F39 Mood [affective] disorders	0.000	0.998	0.002
S93.4 Sprain and strain of ankle	0.002	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.002	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.002	0.998	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.002	0.998	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
F80-F89 Disorders of psychological development	0.000	0.998	0.002
H33.2 Serous retinal detachment	0.000	0.998	0.002
F25.9 Schizoaffective disorder, unspecified	0.000	0.998	0.002
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.000	0.998	0.002
F22.9 Persistent delusional disorder, unspecified	0.000	0.998	0.002
F22.8 Other persistent delusional disorders	0.000	0.998	0.002
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.998	0.002
H50.1 Divergent concomitant strabismus	0.000	0.998	0.002
F60.3 Emotionally unstable personality disorder	0.000	0.998	0.002
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.998	0.002
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.000	0.998	0.002
F51 Nonorganic sleep disorders	0.000	0.998	0.002
F50 Eating disorders	0.000	0.998	0.002
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors	0.000	0.998	0.002
F55 Abuse of non-dependence-producing substances	0.000	0.998	0.002
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere	0.000	0.998	0.002
S92.51 Fracture of other toe (open)	0.002	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.998	0.002
T50.8 Diagnostic agents	0.000	0.998	0.002
T50.7 Analeptics and opioid receptor antagonists	0.000	0.998	0.002
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.002
T50.5 Appetite depressants	0.000	0.998	0.002
T50.4 Drugs affecting uric acid metabolism	0.000	0.998	0.002
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.998	0.002
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.998	0.002
T50.1 Loop [high-ceiling] diuretics	0.000	0.998	0.002
T50.0 Mineralocorticoids and their antagonists	0.000	0.998	0.002
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.002	0.998	0.000
F68 Other disorders of adult personality and behaviour	0.000	0.998	0.002
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.000	0.998	0.002
F65 Disorders of sexual preference	0.000	0.998	0.002
F63 Habit and impulse disorders	0.000	0.998	0.002
F62 Enduring personality changes, not attributable to brain damage and disease	0.000	0.998	0.002
F69 Unspecified disorder of adult personality and behaviour	0.000	0.998	0.002
F61 Mixed and other personality disorders	0.000	0.998	0.002
H04.2 Epiphora	0.000	0.998	0.002
N28.1 Cyst of kidney, acquired	0.002	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.002	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.002	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.002	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.002	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.002	0.998	0.000
S94.1 Injury of medial plantar nerve	0.002	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.002	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.002	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.002	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.002	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.002	0.998	0.000
S95.1 Injury of plantar artery of foot	0.002	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.002	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.002	0.998	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.002	0.998	0.000
S97.1 Crushing injury of toe(s)	0.002	0.998	0.000
S97.0 Crushing injury of ankle	0.002	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.002	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.002	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.002	0.998	0.000
S98.1 Traumatic amputation of one toe	0.002	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.002	0.998	0.000
C44 Other malignant neoplasms of skin	0.000	0.998	0.002
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
F23.8 Other acute and transient psychotic disorders	0.000	0.998	0.002
F23.3 Other acute predominantly delusional psychotic disorders	0.000	0.998	0.002
F23.2 Acute schizophrenia-like psychotic disorder	0.000	0.998	0.002
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.000	0.998	0.002
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.000	0.998	0.002
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.998	0.002
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.998	0.002
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.998	0.002
A08.4 Viral intestinal infection, unspecified	0.000	0.998	0.002
F79 Unspecified mental retardation	0.000	0.998	0.002
F78 Other mental retardation	0.000	0.998	0.002
F73 Profound mental retardation	0.000	0.998	0.002
F72 Severe mental retardation	0.000	0.998	0.002
F71 Moderate mental retardation	0.000	0.998	0.002
F70 Mild mental retardation	0.000	0.998	0.002
F98 Other behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.000	0.998	0.002
F95 Tic disorders	0.000	0.998	0.002
F94 Disorders of social functioning with onset specific to childhood and adolescence	0.000	0.998	0.002
F93 Emotional disorders with onset specific to childhood	0.000	0.998	0.002
F92 Mixed disorders of conduct and emotions	0.000	0.998	0.002
F91 Conduct disorders	0.000	0.998	0.002
F90 Hyperkinetic disorders	0.000	0.998	0.002
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.998	0.002
S92.21 Fracture of other tarsal bone(s) (open)	0.002	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
S92.41 Fracture of great toe (open)	0.002	0.998	0.000
S92.40 Fracture of great toe (closed)	0.002	0.998	0.000
S92.71 Multiple fractures of foot (open)	0.002	0.998	0.000
S92.70 Multiple fractures of foot (closed)	0.002	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.002	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.002	0.998	0.000
F33.8 Other recurrent depressive disorders	0.000	0.998	0.002
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.998	0.002
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.998	0.002
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.998	0.002
S93.1 Dislocation of toe(s)	0.002	0.998	0.000
C44.6 Skin of upper limb, including shoulder	0.000	0.998	0.002
S32.5 Fracture of pubis	0.000	0.998	0.002
T38.9 Other and unspecified hormone antagonists	0.000	0.998	0.002
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.002
T38.7 Androgens and anabolic congeners	0.000	0.998	0.002
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.998	0.002
T38.5 Other oestrogens and progestogens	0.000	0.998	0.002
T38.4 Oral contraceptives	0.000	0.998	0.002
T38.2 Antithyroid drugs	0.000	0.998	0.002
T38.1 Thyroid hormones and substitutes	0.000	0.998	0.002
T38.0 Glucocorticoids and synthetic analogues	0.000	0.998	0.002
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.998	0.002
S92.11 Fracture of talus (open)	0.002	0.998	0.000
D03.9 Melanoma in situ, unspecified	0.002	0.998	0.000
D03.8 Melanoma in situ of other sites	0.002	0.998	0.000
D03.4 Melanoma in situ of scalp and neck	0.002	0.998	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.002	0.998	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.002	0.998	0.000
D03.0 Melanoma in situ of lip	0.002	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.998	0.002
S91.1 Open wound of toe(s) without damage to nail	0.002	0.998	0.000
F64 Gender identity disorders	0.000	0.998	0.002
T36.9 Systemic antibiotic, unspecified	0.000	0.998	0.002
T36.8 Other systemic antibiotics	0.000	0.998	0.002
T36.7 Antifungal antibiotics, systemically used	0.000	0.998	0.002
T36.6 Rifamycins	0.000	0.998	0.002
T36.5 Aminoglycosides	0.000	0.998	0.002
T36.4 Tetracyclines	0.000	0.998	0.002
T36.3 Macrolides	0.000	0.998	0.002
T36.2 Chloramphenicol group	0.000	0.998	0.002
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.998	0.002
T36.0 Penicillins	0.000	0.998	0.002
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.002
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.002
T37.5 Antiviral drugs	0.000	0.998	0.002
T37.4 Anthelminthics	0.000	0.998	0.002
T37.3 Other antiprotozoal drugs	0.000	0.998	0.002
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.002
T37.1 Antimycobacterial drugs	0.000	0.998	0.002
T37.0 Sulphonamides	0.000	0.998	0.002
T41.5 Therapeutic gases	0.000	0.998	0.002
T41.4 Anaesthetic, unspecified	0.000	0.998	0.002
T41.3 Local anaesthetics	0.000	0.998	0.002
T41.2 Other and unspecified general anaesthetics	0.000	0.998	0.002
T41.1 Intravenous anaesthetics	0.000	0.998	0.002
T41.0 Inhaled anaesthetics	0.000	0.998	0.002
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.998	0.002
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.998	0.002
T48.5 Anti-common-cold drugs	0.000	0.998	0.002
T48.4 Expectorants	0.000	0.998	0.002
T48.3 Antitussives	0.000	0.998	0.002
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.998	0.002
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.002
T48.0 Oxytocic drugs	0.000	0.998	0.002
T49.9 Topical agent, unspecified	0.000	0.998	0.002
T49.8 Other topical agents	0.000	0.998	0.002
T49.7 Dental drugs, topically applied	0.000	0.998	0.002
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.998	0.002
T49.5 Ophthalmological drugs and preparations	0.000	0.998	0.002
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.998	0.002
T49.3 Emollients, demulcents and protectants	0.000	0.998	0.002
T49.2 Local astringents and local detergents	0.000	0.998	0.002
T49.1 Antipruritics	0.000	0.998	0.002
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.998	0.002
S92.31 Fracture of metatarsal bone (open)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations