TreeWAS – Variant ID: rs12295638

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R94.3 Abnormal results of cardiovascular function studies	0.015	0.985	0.000
E87.6 Hypokalaemia	0.000	0.988	0.012
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.988	0.012
C78.7 Secondary malignant neoplasm of liver	0.000	0.988	0.012
R94.5 Abnormal results of liver function studies	0.011	0.989	0.000
R94 Abnormal results of function studies	0.011	0.989	0.000
C78.0 Secondary malignant neoplasm of lung	0.000	0.990	0.010
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.990	0.010
C78.2 Secondary malignant neoplasm of pleura	0.000	0.990	0.010
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.990	0.010
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.990	0.010
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.991	0.009
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.991	0.009
R94.6 Abnormal results of thyroid function studies	0.008	0.992	0.000
R94.2 Abnormal results of pulmonary function studies	0.008	0.992	0.000
R94.8 Abnormal results of function studies of other organs and systems	0.008	0.992	0.000
R94.7 Abnormal results of other endocrine function studies	0.008	0.992	0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.008	0.992	0.000
R94.0 Abnormal results of function studies of central nervous system	0.008	0.992	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.993	0.007
C67.3 Anterior wall of bladder	0.007	0.993	0.000
C18.9 Colon, unspecified	0.000	0.993	0.007
C67 Malignant neoplasm of bladder	0.007	0.993	0.000
C67.1 Dome of bladder	0.006	0.994	0.000
R94.4 Abnormal results of kidney function studies	0.006	0.994	0.000
C67.4 Posterior wall of bladder	0.006	0.994	0.000
C67.2 Lateral wall of bladder	0.006	0.994	0.000
K50.9 Crohn's disease, unspecified	0.000	0.994	0.006
C67.0 Trigone of bladder	0.006	0.994	0.000
T39.0 Salicylates	0.006	0.994	0.000
Z88.6 Personal history of allergy to analgesic agent	0.005	0.995	0.000
T90.9 Sequelae of unspecified injury of head	0.005	0.995	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.005	0.995	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.005	0.995	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.005	0.995	0.000
C67.8 Overlapping lesion of bladder	0.005	0.995	0.000
C67.7 Urachus	0.005	0.995	0.000
C67.5 Bladder neck	0.005	0.995	0.000
C67.6 Ureteric orifice	0.005	0.995	0.000
I84.4 External haemorrhoids with other complications	0.005	0.995	0.000
C67.9 Bladder, unspecified	0.005	0.995	0.000
K66.0 Peritoneal adhesions	0.005	0.995	0.000
Z51.5 Palliative care	0.000	0.995	0.005
K50.0 Crohn's disease of small intestine	0.000	0.995	0.005
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.005	0.995	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
H50.9 Strabismus, unspecified	0.000	0.995	0.005
T46.4 Angiotensin-converting-enzyme inhibitors	0.005	0.995	0.000
D86.9 Sarcoidosis, unspecified	0.005	0.995	0.000
T46.1 Calcium-channel blockers	0.004	0.995	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.995	0.005
D86 Sarcoidosis	0.004	0.996	0.000
H50.1 Divergent concomitant strabismus	0.000	0.996	0.004
K08.3 Retained dental root	0.000	0.996	0.004
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.004	0.996	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.004	0.996	0.000
H18 Other disorders of cornea	0.004	0.996	0.000
C77.5 Intrapelvic lymph nodes	0.000	0.996	0.004
T45.0 Antiallergic and antiemetic drugs	0.004	0.996	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.004	0.996	0.000
D86.1 Sarcoidosis of lymph nodes	0.004	0.996	0.000
T39.1 4-Aminophenol derivatives	0.004	0.996	0.000
C77.9 Lymph node, unspecified	0.000	0.996	0.004
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.004	0.996	0.000
C77.4 Inguinal and lower limb lymph nodes	0.000	0.996	0.004
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
K50.8 Other Crohn's disease	0.000	0.996	0.004
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
T36 Poisoning by systemic antibiotics	0.004	0.996	0.000
D86.0 Sarcoidosis of lung	0.004	0.996	0.000
T39.4 Antirheumatics, not elsewhere classified	0.004	0.996	0.000
T39.2 Pyrazolone derivatives	0.004	0.996	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.004	0.996	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.004	0.996	0.000
T46.7 Peripheral vasodilators	0.004	0.996	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.004	0.996	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.004	0.996	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.004	0.996	0.000
T45.5 Anticoagulants	0.004	0.996	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.004	0.996	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.004	0.996	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.004	0.996	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.004	0.996	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.004	0.996	0.000
H50 Other strabismus	0.000	0.996	0.004
H18.5 Hereditary corneal dystrophies	0.004	0.996	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.996	0.004
H49.2 Sixth [abducent] nerve palsy	0.000	0.996	0.004
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.004	0.996	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.000	0.996	0.004
T43.2 Other and unspecified antidepressants	0.004	0.996	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.996	0.004
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.004	0.996	0.000
H18.1 Bullous keratopathy	0.004	0.996	0.000
H15 Disorders of sclera	0.004	0.996	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.004	0.996	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.996	0.004
S82.80 Fractures of other parts of lower leg (closed)	0.004	0.996	0.000
H18.4 Corneal degeneration	0.004	0.996	0.000
H20 Iridocyclitis	0.004	0.996	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.003	0.996	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.996	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.996	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.996	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.996	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.003	0.996	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.996	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.003	0.996	0.000
T44.0 Anticholinesterase agents	0.003	0.996	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.003	0.996	0.000
T45.8 Other primarily systemic and haematological agents	0.003	0.996	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.996	0.000
T45.6 Fibrinolysis-affecting drugs	0.003	0.996	0.000
T45.4 Iron and its compounds	0.003	0.996	0.000
T45.3 Enzymes, not elsewhere classified	0.003	0.996	0.000
T45.2 Vitamins, not elsewhere classified	0.003	0.996	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.004	0.996	0.000
H18.9 Disorder of cornea, unspecified	0.004	0.996	0.000
C18 Malignant neoplasm of colon	0.000	0.996	0.004
T45.1 Antineoplastic and immunosuppressive drugs	0.003	0.997	0.000
D80-D89 Certain disorders involving the immune mechanism	0.003	0.997	0.000
D86.3 Sarcoidosis of skin	0.003	0.997	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.003	0.997	0.000
H18.8 Other specified disorders of cornea	0.003	0.997	0.000
S91 Open wound of ankle and foot	0.003	0.997	0.000
H15.8 Other disorders of sclera	0.003	0.997	0.000
T43.6 Psychostimulants with abuse potential	0.003	0.997	0.000
T90 Sequelae of injuries of head	0.003	0.997	0.000
C18.3 Hepatic flexure	0.000	0.997	0.003
H16 Keratitis	0.003	0.997	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.003	0.997	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.003	0.997	0.000
H20.9 Iridocyclitis, unspecified	0.003	0.997	0.000
S91.3 Open wound of other parts of foot	0.003	0.997	0.000
T36.0 Penicillins	0.003	0.997	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.003	0.997	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
H18.7 Other corneal deformities	0.003	0.997	0.000
H18.3 Changes in corneal membranes	0.003	0.997	0.000
H18.2 Other corneal oedema	0.003	0.997	0.000
H18.0 Corneal pigmentations and deposits	0.003	0.997	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
C18.4 Transverse colon	0.000	0.997	0.003
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.003	0.997	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.003	0.997	0.000
T42.3 Barbiturates	0.003	0.997	0.000
T42.2 Succinimides and oxazolidinediones	0.003	0.997	0.000
T42.0 Hydantoin derivatives	0.003	0.997	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.003	0.997	0.000
C18.7 Sigmoid colon	0.000	0.997	0.003
D83 Common variable immunodeficiency	0.003	0.997	0.000
H15.1 Episcleritis	0.003	0.997	0.000
S90-S99 Injuries to the ankle and foot	0.003	0.997	0.000
S82.8 Fractures of other parts of lower leg	0.003	0.997	0.000
S91.1 Open wound of toe(s) without damage to nail	0.003	0.997	0.000
T36.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
T36.8 Other systemic antibiotics	0.003	0.997	0.000
T36.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
T36.6 Rifamycins	0.003	0.997	0.000
T36.5 Aminoglycosides	0.003	0.997	0.000
T36.4 Tetracyclines	0.003	0.997	0.000
T36.3 Macrolides	0.003	0.997	0.000
T36.2 Chloramphenicol group	0.003	0.997	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.003	0.997	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.003	0.997	0.000
T43.9 Psychotropic drug, unspecified	0.003	0.997	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.003	0.997	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.003	0.997	0.000
T50.8 Diagnostic agents	0.003	0.997	0.000
T50.7 Analeptics and opioid receptor antagonists	0.003	0.997	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.003	0.997	0.000
T50.5 Appetite depressants	0.003	0.997	0.000
T50.4 Drugs affecting uric acid metabolism	0.003	0.997	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.003	0.997	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.003	0.997	0.000
T50.1 Loop [high-ceiling] diuretics	0.003	0.997	0.000
T50.0 Mineralocorticoids and their antagonists	0.003	0.997	0.000
R80 Isolated proteinuria	0.000	0.997	0.003
M22.8 Other disorders of patella	0.003	0.997	0.000
T93 Sequelae of injuries of lower limb	0.003	0.997	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.003	0.997	0.000
H49 Paralytic strabismus	0.000	0.997	0.003
D86.8 Sarcoidosis of other and combined sites	0.003	0.997	0.000
H20.8 Other iridocyclitis	0.003	0.997	0.000
H20.1 Chronic iridocyclitis	0.003	0.997	0.000
M22.0 Recurrent dislocation of patella	0.003	0.997	0.000
T42.4 Benzodiazepines	0.003	0.997	0.000
D83.9 Common variable immunodeficiency, unspecified	0.003	0.997	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.003	0.997	0.000
T37.5 Antiviral drugs	0.003	0.997	0.000
T37.4 Anthelminthics	0.003	0.997	0.000
T37.3 Other antiprotozoal drugs	0.003	0.997	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
T37.1 Antimycobacterial drugs	0.003	0.997	0.000
T37.0 Sulphonamides	0.003	0.997	0.000
T41.5 Therapeutic gases	0.003	0.997	0.000
T41.4 Anaesthetic, unspecified	0.003	0.997	0.000
T41.3 Local anaesthetics	0.003	0.997	0.000
T41.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
T41.1 Intravenous anaesthetics	0.003	0.997	0.000
T41.0 Inhaled anaesthetics	0.003	0.997	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.003	0.997	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.003	0.997	0.000
T48.5 Anti-common-cold drugs	0.003	0.997	0.000
T48.4 Expectorants	0.003	0.997	0.000
T48.3 Antitussives	0.003	0.997	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.003	0.997	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.003	0.997	0.000
T48.0 Oxytocic drugs	0.003	0.997	0.000
T49.9 Topical agent, unspecified	0.003	0.997	0.000
T49.8 Other topical agents	0.003	0.997	0.000
T49.7 Dental drugs, topically applied	0.003	0.997	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.003	0.997	0.000
T49.5 Ophthalmological drugs and preparations	0.003	0.997	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.997	0.000
T49.3 Emollients, demulcents and protectants	0.003	0.997	0.000
T49.2 Local astringents and local detergents	0.003	0.997	0.000
T49.1 Antipruritics	0.003	0.997	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.003	0.997	0.000
F10.1 Harmful use	0.003	0.997	0.000
H18.6 Keratoconus	0.003	0.997	0.000
H90.5 Sensorineural hearing loss, unspecified	0.000	0.997	0.003
T93.1 Sequelae of fracture of femur	0.003	0.997	0.000
H50.8 Other specified strabismus	0.000	0.997	0.003
H50.6 Mechanical strabismus	0.000	0.997	0.003
H50.3 Intermittent heterotropia	0.000	0.997	0.003
H50.2 Vertical strabismus	0.000	0.997	0.003
M22 Disorders of patella	0.003	0.997	0.000
H16.0 Corneal ulcer	0.003	0.997	0.000
H17 Corneal scars and opacities	0.003	0.997	0.000
R02 Gangrene, not elsewhere classified	0.003	0.997	0.000
T93.2 Sequelae of other fractures of lower limb	0.003	0.997	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.003	0.997	0.000
K50.1 Crohn's disease of large intestine	0.000	0.997	0.003
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.003	0.997	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.003	0.997	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
T47.7 Emetics	0.003	0.997	0.000
T47.6 Antidiarrhoeal drugs	0.003	0.997	0.000
T47.5 Digestants	0.003	0.997	0.000
T47.4 Other laxatives	0.003	0.997	0.000
T47.3 Saline and osmotic laxatives	0.003	0.997	0.000
T47.2 Stimulant laxatives	0.003	0.997	0.000
T47.0 Histamine H(2)-receptor antagonists	0.003	0.997	0.000
S99 Other and unspecified injuries of ankle and foot	0.003	0.997	0.000
S90 Superficial injury of ankle and foot	0.003	0.997	0.000
C77.8 Lymph nodes of multiple regions	0.000	0.997	0.003
H15.9 Disorder of sclera, unspecified	0.003	0.997	0.000
H15.0 Scleritis	0.003	0.997	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.003	0.997	0.000
M22.2 Patellofemoral disorders	0.003	0.997	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.003	0.997	0.000
M24.07 Loose body in joint (Ankle and foot)	0.003	0.997	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.003	0.997	0.000
S19.9 Unspecified injury of neck	0.003	0.997	0.000
H20.2 Lens-induced iridocyclitis	0.003	0.997	0.000
S82.2 Fracture of shaft of tibia	0.003	0.997	0.000
T42.1 Iminostilbenes	0.003	0.997	0.000
H50.5 Heterophoria	0.000	0.997	0.003
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.997	0.003
J30.1 Allergic rhinitis due to pollen	0.003	0.997	0.000
Y40.0 Penicillins	0.000	0.997	0.003
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.003	0.997	0.000
S91.0 Open wound of ankle	0.003	0.997	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.003	0.997	0.000
D80 Immunodeficiency with predominantly antibody defects	0.003	0.997	0.000
S19 Other and unspecified injuries of neck	0.003	0.997	0.000
M25.31 Other instability of joint (Shoulder region)	0.003	0.997	0.000
S69.9 Unspecified injury of wrist and hand	0.003	0.997	0.000
D84 Other immunodeficiencies	0.003	0.997	0.000
S82.0 Fracture of patella	0.003	0.997	0.000
T90.1 Sequelae of open wound of head	0.003	0.997	0.000
C18.1 Appendix	0.000	0.997	0.003
S99.9 Unspecified injury of ankle and foot	0.003	0.997	0.000
D82 Immunodeficiency associated with other major defects	0.003	0.997	0.000
D81 Combined immunodeficiencies	0.003	0.997	0.000
S91.7 Multiple open wounds of ankle and foot	0.003	0.997	0.000
S91.2 Open wound of toe(s) with damage to nail	0.003	0.997	0.000
T90.3 Sequelae of injury of cranial nerves	0.003	0.997	0.000
T90.0 Sequelae of superficial injury of head	0.003	0.997	0.000
S82 Fracture of lower leg, including ankle	0.003	0.997	0.000
C64-C68 Malignant neoplasms of urinary tract	0.003	0.997	0.000
H16.8 Other keratitis	0.003	0.997	0.000
H16.4 Corneal neovascularisation	0.003	0.997	0.000
H16.3 Interstitial and deep keratitis	0.003	0.997	0.000
H16.2 Keratoconjunctivitis	0.003	0.997	0.000
K14.8 Other diseases of tongue	0.000	0.997	0.003
S82.20 Fracture of shaft of tibia (closed)	0.003	0.997	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.003	0.997	0.000
D89.3 Immune reconstitution syndrome	0.003	0.997	0.000
D89.1 Cryoglobulinaemia	0.003	0.997	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.003	0.997	0.000
S90.0 Contusion of ankle	0.003	0.997	0.000
T90.8 Sequelae of other specified injuries of head	0.003	0.997	0.000
S82.21 Fracture of shaft of tibia (open)	0.003	0.997	0.000
C18.8 Overlapping lesion of colon	0.000	0.997	0.003
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.003	0.997	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.003	0.997	0.000
H49.1 Fourth [trochlear] nerve palsy	0.000	0.997	0.003
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.997	0.000
C18.6 Descending colon	0.000	0.997	0.003
C18.2 Ascending colon	0.000	0.997	0.003
H16.9 Keratitis, unspecified	0.003	0.997	0.000
M25.37 Other instability of joint (Ankle and foot)	0.003	0.997	0.000
S82.00 Fracture of patella (closed)	0.003	0.997	0.000
S82.81 Fractures of other parts of lower leg (open)	0.003	0.997	0.000
H50.0 Convergent concomitant strabismus	0.000	0.997	0.003
M25.3 Other instability of joint	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.002	0.997	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.997	0.000
T38.7 Androgens and anabolic congeners	0.002	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.002	0.997	0.000
T38.5 Other oestrogens and progestogens	0.002	0.997	0.000
T38.4 Oral contraceptives	0.002	0.997	0.000
T38.2 Antithyroid drugs	0.002	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.002	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.002	0.997	0.000
T93.0 Sequelae of open wound of lower limb	0.003	0.997	0.000
C77.1 Intrathoracic lymph nodes	0.000	0.997	0.003
M22.4 Chondromalacia patellae	0.003	0.997	0.000
S19.8 Other specified injuries of neck	0.003	0.997	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.003	0.997	0.000
D83.8 Other common variable immunodeficiencies	0.002	0.997	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.997	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.997	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.997	0.000
H17.8 Other corneal scars and opacities	0.002	0.997	0.000
S90.8 Other superficial injuries of ankle and foot	0.003	0.997	0.000
H10.9 Conjunctivitis, unspecified	0.003	0.997	0.000
H20.0 Acute and subacute iridocyclitis	0.002	0.997	0.000
H50.4 Other and unspecified heterotropia	0.000	0.997	0.002
J38.3 Other diseases of vocal cords	0.000	0.997	0.003
T92.9 Sequelae of unspecified injury of upper limb	0.003	0.997	0.000
S98 Traumatic amputation of ankle and foot	0.002	0.997	0.000
S97 Crushing injury of ankle and foot	0.002	0.997	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.997	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.997	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.997	0.000
S82.86 Maisonneuve's fracture	0.002	0.997	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.002	0.997	0.000
S69 Other and unspecified injuries of wrist and hand	0.003	0.997	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.000	0.997	0.003
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.002	0.997	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.002	0.997	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.003	0.997	0.000
M24.01 Loose body in joint (Shoulder region)	0.002	0.997	0.000
H49.9 Paralytic strabismus, unspecified	0.000	0.997	0.002
H49.8 Other paralytic strabismus	0.000	0.997	0.002
H49.4 Progressive external ophthalmoplegia	0.000	0.997	0.002
H49.3 Total (external) ophthalmoplegia	0.000	0.997	0.002
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.997	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.003	0.997	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.997	0.000
S82.01 Fracture of patella (open)	0.002	0.997	0.000
E87.3 Alkalosis	0.000	0.997	0.002
M24.0 Loose body in joint	0.002	0.997	0.000
H21 Other disorders of iris and ciliary body	0.002	0.997	0.000
T98 Sequelae of other and unspecified effects of external causes	0.002	0.997	0.000
T95 Sequelae of burns, corrosions and frostbite	0.002	0.997	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.002	0.997	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.002	0.997	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.000	0.997	0.003
S10-S19 Injuries to the neck	0.002	0.997	0.000
M25.34 Other instability of joint (Hand)	0.002	0.998	0.000
M25.33 Other instability of joint (Forearm)	0.002	0.998	0.000
H49.0 Third [oculomotor] nerve palsy	0.000	0.998	0.002
M22.1 Recurrent subluxation of patella	0.002	0.998	0.000
M22.9 Disorder of patella, unspecified	0.002	0.998	0.000
T79.8 Other early complications of trauma	0.002	0.998	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.002	0.998	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.998	0.002
T92 Sequelae of injuries of upper limb	0.002	0.998	0.000
T90.5 Sequelae of intracranial injury	0.002	0.998	0.000
C80 Malignant neoplasm without specification of site	0.000	0.998	0.002
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.998	0.002
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.000	0.998	0.002
H17.1 Other central corneal opacity	0.002	0.998	0.000
H17.0 Adherent leukoma	0.002	0.998	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.998	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.002	0.998	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.002	0.998	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.002	0.998	0.000
C18.5 Splenic flexure	0.000	0.998	0.002
S59.9 Unspecified injury of forearm	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.998	0.000
S82.7 Multiple fractures of lower leg	0.002	0.998	0.000
T40.6 Other and unspecified narcotics	0.002	0.998	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.002	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
S99.8 Other specified injuries of ankle and foot	0.002	0.998	0.000
S99.7 Multiple injuries of ankle and foot	0.002	0.998	0.000
C66 Malignant neoplasm of ureter	0.002	0.998	0.000
S60-S69 Injuries to the wrist and hand	0.002	0.998	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.002	0.998	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.002	0.998	0.000
T40.8 Lysergide [LSD]	0.002	0.998	0.000
T40.7 Cannabis (derivatives)	0.002	0.998	0.000
T40.5 Cocaine	0.002	0.998	0.000
T40.3 Methadone	0.002	0.998	0.000
T40.1 Heroin	0.002	0.998	0.000
T40.0 Opium	0.002	0.998	0.000
T91 Sequelae of injuries of neck and trunk	0.002	0.998	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.002	0.998	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.002	0.998	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.998	0.000
S19.7 Multiple injuries of neck	0.002	0.998	0.000
S60.8 Other superficial injuries of wrist and hand	0.002	0.998	0.000
T90.4 Sequelae of injury of eye and orbit	0.002	0.998	0.000
D84.8 Other specified immunodeficiencies	0.002	0.998	0.000
D84.1 Defects in the complement system	0.002	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.998	0.000
I67.8 Other specified cerebrovascular diseases	0.002	0.998	0.000
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
C65 Malignant neoplasm of renal pelvis	0.002	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.998	0.000
D82.1 Di George's syndrome	0.002	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.998	0.000
M34.1 CR(E)ST syndrome	0.002	0.998	0.000
S82.9 Fracture of lower leg, part unspecified	0.002	0.998	0.000
M34 Systemic sclerosis	0.002	0.998	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
H17.9 Corneal scar and opacity, unspecified	0.002	0.998	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.002	0.998	0.000
S59 Other and unspecified injuries of forearm	0.002	0.998	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.002	0.998	0.000
S92.4 Fracture of great toe	0.002	0.998	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.002	0.998	0.000
S82.6 Fracture of lateral malleolus	0.002	0.998	0.000
S60 Superficial injury of wrist and hand	0.002	0.998	0.000
T79-T79 Certain early complications of trauma	0.002	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.002	0.998	0.000
S82.4 Fracture of fibula alone	0.002	0.998	0.000
M25.39 Other instability of joint (Site unspecified)	0.002	0.998	0.000
M25.38 Other instability of joint (Other)	0.002	0.998	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.002	0.998	0.000
M25.32 Other instability of joint (Upper arm)	0.002	0.998	0.000
M25.30 Other instability of joint (Multiple sites)	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
K81.1 Chronic cholecystitis	0.002	0.998	0.000
M34.8 Other forms of systemic sclerosis	0.002	0.998	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.002	0.998	0.000
S11 Open wound of neck	0.002	0.998	0.000
S10 Superficial injury of neck	0.002	0.998	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.998	0.002
E06.3 Autoimmune thyroiditis	0.002	0.998	0.000
S82.70 Multiple fractures of lower leg (closed)	0.002	0.998	0.000
E87.0 Hyperosmolality and hypernatraemia	0.000	0.998	0.002
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
S67 Crushing injury of wrist and hand	0.002	0.998	0.000
S50-S59 Injuries to the elbow and forearm	0.002	0.998	0.000
S69.8 Other specified injuries of wrist and hand	0.002	0.998	0.000
S69.7 Multiple injuries of wrist and hand	0.002	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.002	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.002	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.002	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.002	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.002	0.998	0.000
S94.1 Injury of medial plantar nerve	0.002	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.002	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.002	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.002	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.002	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.002	0.998	0.000
S95.1 Injury of plantar artery of foot	0.002	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations