TreeWAS – Variant ID: rs1233387

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.003	0.997
E00-E07 Disorders of thyroid gland	0.000	0.004	0.996
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.005	0.995
E05.9 Thyrotoxicosis, unspecified	0.000	0.010	0.990
L40 Psoriasis	0.987	0.013	0.000
L40.5 Arthropathic psoriasis	0.974	0.026	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.041	0.959
E06 Thyroiditis	0.000	0.045	0.955
E06.3 Autoimmune thyroiditis	0.000	0.077	0.923
L40.4 Guttate psoriasis	0.824	0.176	0.000
L40.0 Psoriasis vulgaris	0.805	0.195	0.000
L40.1 Generalised pustular psoriasis	0.789	0.211	0.000
E06.9 Thyroiditis, unspecified	0.000	0.213	0.787
E07 Other disorders of thyroid	0.000	0.225	0.775
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.225	0.775
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.231	0.769
L40.8 Other psoriasis	0.741	0.259	0.000
E05.8 Other thyrotoxicosis	0.000	0.277	0.722
E03.5 Myxoedema coma	0.000	0.285	0.715
E03.4 Atrophy of thyroid (acquired)	0.000	0.285	0.715
E03.3 Postinfectious hypothyroidism	0.000	0.285	0.715
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.286	0.714
E00 Congenital iodine-deficiency syndrome	0.000	0.286	0.714
E05.5 Thyroid crisis or storm	0.000	0.287	0.713
E05.4 Thyrotoxicosis factitia	0.000	0.287	0.713
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.287	0.713
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.287	0.713
L40.3 Pustulosis palmaris et plantaris	0.708	0.292	0.000
L40.2 Acrodermatitis continua	0.708	0.292	0.000
E06.4 Drug-induced thyroiditis	0.000	0.315	0.685
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.315	0.685
E06.0 Acute thyroiditis	0.000	0.315	0.685
E03.8 Other specified hypothyroidism	0.000	0.337	0.663
E03.1 Congenital hypothyroidism without goitre	0.000	0.351	0.649
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.351	0.649
K90 Intestinal malabsorption	0.000	0.360	0.640
E06.1 Subacute thyroiditis	0.000	0.361	0.638
E07.8 Other specified disorders of thyroid	0.000	0.378	0.622
E06.5 Other chronic thyroiditis	0.000	0.382	0.617
E07.1 Dyshormogenetic goitre	0.000	0.444	0.556
E07.0 Hypersecretion of calcitonin	0.000	0.444	0.556
E07.9 Disorder of thyroid, unspecified	0.000	0.452	0.548
K90.9 Intestinal malabsorption, unspecified	0.000	0.461	0.539
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.478	0.521
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.488	0.512
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.488	0.512
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.488	0.512
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.488	0.512
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.488	0.512
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.488	0.512
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.488	0.512
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.488	0.512
K90.8 Other intestinal malabsorption	0.000	0.509	0.490
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.529	0.471
K90.3 Pancreatic steatorrhoea	0.000	0.541	0.459
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.541	0.459
K90.1 Tropical sprue	0.000	0.541	0.459
E04 Other non-toxic goitre	0.000	0.679	0.321
E83.1 Disorders of iron metabolism	0.000	0.752	0.248
E04.0 Non-toxic diffuse goitre	0.000	0.754	0.246
E04.8 Other specified non-toxic goitre	0.000	0.770	0.230
E04.2 Non-toxic multinodular goitre	0.000	0.794	0.206
L40-L45 Papulosquamous disorders	0.194	0.806	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.838	0.162
E83 Disorders of mineral metabolism	0.000	0.840	0.160
E04.9 Non-toxic goitre, unspecified	0.000	0.841	0.159
E40-E46 Malnutrition	0.000	0.845	0.155
E46 Unspecified protein-energy malnutrition	0.000	0.850	0.150
L44 Other papulosquamous disorders	0.139	0.861	0.000
L41 Parapsoriasis	0.139	0.861	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.139	0.861	0.000
E70-E90 Metabolic disorders	0.000	0.862	0.138
E83.4 Disorders of magnesium metabolism	0.000	0.880	0.120
E27.1 Primary adrenocortical insufficiency	0.000	0.883	0.117
L42 Pityriasis rosea	0.116	0.884	0.000
E74 Other disorders of carbohydrate metabolism	0.000	0.884	0.116
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.885	0.115
E83.8 Other disorders of mineral metabolism	0.000	0.885	0.115
E83.2 Disorders of zinc metabolism	0.000	0.885	0.115
E83.0 Disorders of copper metabolism	0.000	0.885	0.115
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.889	0.111
E45 Retarded development following protein-energy malnutrition	0.000	0.889	0.111
E43 Unspecified severe protein-energy malnutrition	0.000	0.889	0.111
E42 Marasmic kwashiorkor	0.000	0.889	0.111
E41 Nutritional marasmus	0.000	0.889	0.111
E40 Kwashiorkor	0.000	0.889	0.111
E85 Amyloidosis	0.000	0.890	0.110
E27 Other disorders of adrenal gland	0.000	0.890	0.110
E83.3 Disorders of phosphorus metabolism	0.000	0.890	0.110
E20-E35 Disorders of other endocrine glands	0.000	0.894	0.106
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.900	0.100
E79 Disorders of purine and pyrimidine metabolism	0.000	0.900	0.100
L41.9 Parapsoriasis, unspecified	0.100	0.900	0.000
L41.8 Other parapsoriasis	0.100	0.900	0.000
L41.5 Retiform parapsoriasis	0.100	0.900	0.000
L41.4 Large plaque parapsoriasis	0.100	0.900	0.000
L41.3 Small plaque parapsoriasis	0.100	0.900	0.000
L41.2 Lymphomatoid papulosis	0.100	0.900	0.000
L41.1 Pityriasis lichenoides chronica	0.100	0.900	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.100	0.900	0.000
L44.9 Papulosquamous disorder, unspecified	0.100	0.900	0.000
L44.8 Other specified papulosquamous disorders	0.100	0.900	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.100	0.900	0.000
L44.3 Lichen ruber moniliformis	0.100	0.900	0.000
L44.2 Lichen striatus	0.100	0.900	0.000
L44.1 Lichen nitidus	0.100	0.900	0.000
L44.0 Pityriasis rubra pilaris	0.100	0.900	0.000
E84 Cystic fibrosis	0.000	0.901	0.099
E77 Disorders of glycoprotein metabolism	0.000	0.901	0.099
E76 Disorders of glycosaminoglycan metabolism	0.000	0.901	0.099
E72 Other disorders of amino-acid metabolism	0.000	0.901	0.099
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.901	0.099
E70 Disorders of aromatic amino-acid metabolism	0.000	0.901	0.099
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.901	0.099
E27.2 Addisonian crisis	0.000	0.905	0.095
E85.9 Amyloidosis, unspecified	0.000	0.909	0.091
E88 Other metabolic disorders	0.000	0.913	0.087
E86 Volume depletion	0.000	0.913	0.087
E85.3 Secondary systemic amyloidosis	0.000	0.914	0.085
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.915	0.085
E20 Hypoparathyroidism	0.000	0.916	0.084
E73 Lactose intolerance	0.000	0.916	0.083
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.917	0.083
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.917	0.083
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.917	0.083
E74.2 Disorders of galactose metabolism	0.000	0.917	0.083
E74.1 Disorders of fructose metabolism	0.000	0.917	0.083
E74.0 Glycogen storage disease	0.000	0.917	0.083
E44.1 Mild protein-energy malnutrition	0.000	0.920	0.080
E44.0 Moderate protein-energy malnutrition	0.000	0.920	0.080
L43 Lichen planus	0.079	0.920	0.000
E85.8 Other amyloidosis	0.000	0.921	0.079
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.921	0.079
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.921	0.079
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.921	0.079
E27.5 Adrenomedullary hyperfunction	0.000	0.921	0.079
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.921	0.079
E27.0 Other adrenocortical overactivity	0.000	0.921	0.079
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.922	0.078
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.923	0.076
E32 Diseases of thymus	0.000	0.923	0.076
E31 Polyglandular dysfunction	0.000	0.923	0.076
E30 Disorders of puberty, not elsewhere classified	0.000	0.923	0.076
E29 Testicular dysfunction	0.000	0.925	0.075
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.927	0.073
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.927	0.073
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.928	0.072
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.928	0.072
E79.1 Lesch-Nyhan syndrome	0.000	0.928	0.072
E28 Ovarian dysfunction	0.000	0.928	0.072
E25 Adrenogenital disorders	0.000	0.929	0.071
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.929	0.071
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.929	0.071
E70.3 Albinism	0.000	0.929	0.071
E70.2 Disorders of tyrosine metabolism	0.000	0.929	0.071
E70.1 Other hyperphenylalaninaemias	0.000	0.929	0.071
E70.0 Classical phenylketonuria	0.000	0.929	0.071
E71.3 Disorders of fatty-acid metabolism	0.000	0.929	0.071
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.929	0.071
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.929	0.071
E71.0 Maple-syrup-urine disease	0.000	0.929	0.071
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.929	0.071
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.929	0.071
E72.5 Disorders of glycine metabolism	0.000	0.929	0.071
E72.4 Disorders of ornithine metabolism	0.000	0.929	0.071
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.929	0.071
E72.2 Disorders of urea cycle metabolism	0.000	0.929	0.071
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.929	0.071
E72.0 Disorders of amino-acid transport	0.000	0.929	0.071
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.929	0.071
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.929	0.071
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.929	0.071
E76.2 Other mucopolysaccharidoses	0.000	0.929	0.071
E76.1 Mucopolysaccharidosis, type II	0.000	0.929	0.071
E76.0 Mucopolysaccharidosis, type I	0.000	0.929	0.071
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.929	0.071
E77.8 Other disorders of glycoprotein metabolism	0.000	0.929	0.071
E77.1 Defects in glycoprotein degradation	0.000	0.929	0.071
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.929	0.071
E84.9 Cystic fibrosis, unspecified	0.000	0.929	0.071
E84.8 Cystic fibrosis with other manifestations	0.000	0.929	0.071
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.929	0.071
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.929	0.071
E85.4 Organ-limited amyloidosis	0.000	0.931	0.069
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.931	0.069
E27.9 Disorder of adrenal gland, unspecified	0.000	0.931	0.069
E20.9 Hypoparathyroidism, unspecified	0.000	0.931	0.069
E34 Other endocrine disorders	0.000	0.934	0.066
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.934	0.066
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.937	0.063
E88.9 Metabolic disorder, unspecified	0.000	0.937	0.063
E04.1 Non-toxic single thyroid nodule	0.000	0.938	0.061
E26 Hyperaldosteronism	0.000	0.938	0.061
E15 Nondiabetic hypoglycaemic coma	0.000	0.939	0.061
E20.8 Other hypoparathyroidism	0.000	0.939	0.061
E20.1 Pseudohypoparathyroidism	0.000	0.939	0.061
E20.0 Idiopathic hypoparathyroidism	0.000	0.939	0.061
E27.8 Other specified disorders of adrenal gland	0.000	0.939	0.061
E88.3 Tumour lysis syndrome	0.000	0.939	0.060
E88.2 Lipomatosis, not elsewhere classified	0.000	0.940	0.060
E73.8 Other lactose intolerance	0.000	0.940	0.060
E73.1 Secondary lactase deficiency	0.000	0.940	0.060
E73.0 Congenital lactase deficiency	0.000	0.940	0.060
E65-E68 Obesity and other hyperalimentation	0.000	0.941	0.059
E88.8 Other specified metabolic disorders	0.000	0.942	0.058
L43.3 Subacute (active) lichen planus	0.057	0.943	0.000
L43.2 Lichenoid drug reaction	0.057	0.943	0.000
L43.1 Bullous lichen planus	0.057	0.943	0.000
L43.0 Hypertrophic lichen planus	0.057	0.943	0.000
E75.6 Lipid storage disorder, unspecified	0.000	0.944	0.056
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.944	0.056
E75.3 Sphingolipidosis, unspecified	0.000	0.944	0.056
E75.1 Other gangliosidosis	0.000	0.944	0.056
E75.0 GM2 gangliosidosis	0.000	0.944	0.056
E50-E64 Other nutritional deficiencies	0.000	0.944	0.056
E30.9 Disorder of puberty, unspecified	0.000	0.945	0.055
E30.8 Other disorders of puberty	0.000	0.945	0.055
E30.1 Precocious puberty	0.000	0.945	0.055
E30.0 Delayed puberty	0.000	0.945	0.055
E31.9 Polyglandular dysfunction, unspecified	0.000	0.945	0.055
E31.8 Other polyglandular dysfunction	0.000	0.945	0.055
E31.1 Polyglandular hyperfunction	0.000	0.945	0.055
E31.0 Autoimmune polyglandular failure	0.000	0.945	0.055
E32.9 Disease of thymus, unspecified	0.000	0.945	0.055
E32.8 Other diseases of thymus	0.000	0.945	0.055
E32.1 Abscess of thymus	0.000	0.945	0.055
E32.0 Persistent hyperplasia of thymus	0.000	0.945	0.055
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.945	0.055
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.945	0.055
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.945	0.055
E22 Hyperfunction of pituitary gland	0.000	0.945	0.055
E29.9 Testicular dysfunction, unspecified	0.000	0.946	0.054
E29.8 Other testicular dysfunction	0.000	0.946	0.054
E29.0 Testicular hyperfunction	0.000	0.946	0.054
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.947	0.053
E29.1 Testicular hypofunction	0.000	0.947	0.053
E28.9 Ovarian dysfunction, unspecified	0.000	0.948	0.051
E28.8 Other ovarian dysfunction	0.000	0.948	0.051
E28.2 Polycystic ovarian syndrome	0.000	0.948	0.052
E28.1 Androgen excess	0.000	0.948	0.051
E28.0 Oestrogen excess	0.000	0.948	0.051
E25.9 Adrenogenital disorder, unspecified	0.000	0.948	0.051
E25.8 Other adrenogenital disorders	0.000	0.948	0.051
E24 Cushing's syndrome	0.000	0.949	0.051
L43.8 Other lichen planus	0.050	0.949	0.000
E75.2 Other sphingolipidosis	0.000	0.950	0.049
E34.0 Carcinoid syndrome	0.000	0.951	0.049
E89.3 Postprocedural hypopituitarism	0.000	0.952	0.048
E34.5 Androgen resistance syndrome	0.000	0.952	0.047
E34.4 Constitutional tall stature	0.000	0.952	0.047
E34.3 Short stature, not elsewhere classified	0.000	0.952	0.047
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.952	0.047
E34.1 Other hypersecretion of intestinal hormones	0.000	0.952	0.047
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.952	0.047
E80.5 Crigler-Najjar syndrome	0.000	0.952	0.047
E80.3 Defects of catalase and peroxydase	0.000	0.952	0.047
E80.1 Porphyria cutanea tarda	0.000	0.952	0.047
E80.0 Hereditary erythropoietic porphyria	0.000	0.952	0.047
E28.3 Primary ovarian failure	0.000	0.953	0.046
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.954	0.046
E75.5 Other lipid storage disorders	0.000	0.954	0.046
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.954	0.045
E89.5 Postprocedural testicular hypofunction	0.000	0.954	0.045
E89.1 Postprocedural hypoinsulinaemia	0.000	0.954	0.045
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.955	0.045
E34.9 Endocrine disorder, unspecified	0.000	0.955	0.045
E80.6 Other disorders of bilirubin metabolism	0.000	0.955	0.045
E73.9 Lactose intolerance, unspecified	0.000	0.955	0.044
E26.9 Hyperaldosteronism, unspecified	0.000	0.956	0.044
E26.8 Other hyperaldosteronism	0.000	0.956	0.044
E26.1 Secondary hyperaldosteronism	0.000	0.956	0.044
E89.4 Postprocedural ovarian failure	0.000	0.956	0.043
E67 Other hyperalimentation	0.000	0.958	0.042
E68 Sequelae of hyperalimentation	0.000	0.958	0.042
E89.0 Postprocedural hypothyroidism	0.000	0.958	0.042
E51 Thiamine deficiency	0.000	0.959	0.041
E80.2 Other porphyria	0.000	0.959	0.041
E58 Dietary calcium deficiency	0.000	0.959	0.040
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.960	0.040
E63 Other nutritional deficiencies	0.000	0.960	0.040
E50 Vitamin A deficiency	0.000	0.960	0.040
E60 Dietary zinc deficiency	0.000	0.960	0.040
E59 Dietary selenium deficiency	0.000	0.960	0.040
E52 Niacin deficiency [pellagra]	0.000	0.960	0.040
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.960	0.040
E22.8 Other hyperfunction of pituitary gland	0.000	0.960	0.040
K90-K93 Other diseases of the digestive system	0.000	0.960	0.040
E56 Other vitamin deficiencies	0.000	0.961	0.039
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.961	0.039
E22.1 Hyperprolactinaemia	0.000	0.962	0.038
E22.0 Acromegaly and pituitary gigantism	0.000	0.962	0.038
E34.8 Other specified endocrine disorders	0.000	0.962	0.037
E24.8 Other Cushing's syndrome	0.000	0.963	0.037
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.963	0.037
E24.3 Ectopic ACTH syndrome	0.000	0.963	0.037
E24.1 Nelson's syndrome	0.000	0.963	0.037
H34.8 Other retinal vascular occlusions	0.000	0.963	0.037
E61 Deficiency of other nutrient elements	0.000	0.964	0.036
E24.2 Drug-induced Cushing's syndrome	0.000	0.964	0.035
E23 Hypofunction and other disorders of pituitary gland	0.000	0.965	0.035
E54 Ascorbic acid deficiency	0.000	0.965	0.035
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.965	0.035
E89.2 Postprocedural hypoparathyroidism	0.000	0.965	0.035
E24.0 Pituitary-dependent Cushing's disease	0.000	0.967	0.032
E65 Localised adiposity	0.000	0.967	0.032
E80.4 Gilbert's syndrome	0.000	0.968	0.032
E51.2 Wernicke's encephalopathy	0.000	0.969	0.031
E67.8 Other specified hyperalimentation	0.000	0.969	0.030
E67.3 Hypervitaminosis D	0.000	0.969	0.030
E67.2 Megavitamin-B6 syndrome	0.000	0.969	0.030
E67.1 Hypercarotenaemia	0.000	0.969	0.030
E67.0 Hypervitaminosis A	0.000	0.969	0.030
E51.9 Thiamine deficiency, unspecified	0.000	0.970	0.030
E51.8 Other manifestations of thiamine deficiency	0.000	0.970	0.030
E51.1 Beriberi	0.000	0.970	0.030
E16 Other disorders of pancreatic internal secretion	0.000	0.970	0.029
E55 Vitamin D deficiency	0.000	0.971	0.029
E26.0 Primary hyperaldosteronism	0.001	0.971	0.029
E50.9 Vitamin A deficiency, unspecified	0.000	0.971	0.029
E50.8 Other manifestations of vitamin A deficiency	0.000	0.971	0.029
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.971	0.029
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.971	0.029
E50.5 Vitamin A deficiency with night blindness	0.000	0.971	0.029
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.971	0.029
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.971	0.029
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.971	0.029
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.971	0.029
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.971	0.029
E63.9 Nutritional deficiency, unspecified	0.000	0.971	0.029
E63.8 Other specified nutritional deficiencies	0.000	0.971	0.029
E63.1 Imbalance of constituents of food intake	0.000	0.971	0.029
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.971	0.029
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.971	0.029
E64.8 Sequelae of other nutritional deficiencies	0.000	0.971	0.029
E64.3 Sequelae of rickets	0.000	0.971	0.029
E64.2 Sequelae of vitamin C deficiency	0.000	0.971	0.029
E64.1 Sequelae of vitamin A deficiency	0.000	0.971	0.029
E64.0 Sequelae of protein-energy malnutrition	0.000	0.971	0.029
E83.5 Disorders of calcium metabolism	0.000	0.971	0.029
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.971	0.029
E53 Deficiency of other B group vitamins	0.000	0.971	0.029
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.971	0.029
E56.9 Vitamin deficiency, unspecified	0.000	0.972	0.028
E56.8 Deficiency of other vitamins	0.000	0.972	0.028
E56.0 Deficiency of vitamin E	0.000	0.972	0.028
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.972	0.028
E21.4 Other specified disorders of parathyroid gland	0.000	0.972	0.028
E61.2 Magnesium deficiency	0.000	0.972	0.027
E56.1 Deficiency of vitamin K	0.000	0.973	0.026
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.000	0.974	0.026
E61.9 Deficiency of nutrient element, unspecified	0.000	0.974	0.026
E61.8 Deficiency of other specified nutrient elements	0.000	0.974	0.026
E61.7 Deficiency of multiple nutrient elements	0.000	0.974	0.026
E61.6 Vanadium deficiency	0.000	0.974	0.026
E61.5 Molybdenum deficiency	0.000	0.974	0.026
E61.4 Chromium deficiency	0.000	0.974	0.026
E61.3 Manganese deficiency	0.000	0.974	0.026
E61.0 Copper deficiency	0.000	0.974	0.026
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.974	0.026
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.974	0.025
E23.1 Drug-induced hypopituitarism	0.000	0.974	0.025
E21.0 Primary hyperparathyroidism	0.000	0.975	0.025
E24.9 Cushing's syndrome, unspecified	0.001	0.976	0.023
E21.2 Other hyperparathyroidism	0.000	0.976	0.023
E23.2 Diabetes insipidus	0.000	0.977	0.023
E23.6 Other disorders of pituitary gland	0.000	0.977	0.023
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.978	0.021
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.978	0.021
E16.4 Abnormal secretion of gastrin	0.000	0.978	0.021
E16.3 Increased secretion of glucagon	0.000	0.978	0.021
E23.7 Disorder of pituitary gland, unspecified	0.000	0.979	0.021
E55.0 Rickets, active	0.000	0.979	0.021
E53.1 Pyridoxine deficiency	0.000	0.979	0.021
E53.0 Riboflavin deficiency	0.000	0.979	0.021
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.979	0.021
K93.1 Megacolon in Chagas' disease	0.000	0.979	0.021
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.979	0.021
E53.9 Vitamin B deficiency, unspecified	0.000	0.979	0.020
E16.1 Other hypoglycaemia	0.000	0.979	0.020
E61.1 Iron deficiency	0.000	0.981	0.019
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.981	0.019
L43.9 Lichen planus, unspecified	0.017	0.983	0.000
G20 Parkinson's disease	0.016	0.984	0.000
E23.0 Hypopituitarism	0.000	0.987	0.013
H34 Retinal vascular occlusions	0.000	0.987	0.013
E66 Obesity	0.000	0.988	0.012
M47.82 Other spondylosis (Cervical region)	0.011	0.989	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.010	0.990	0.000
M47.89 Other spondylosis (Site unspecified)	0.010	0.990	0.000
M47.8 Other spondylosis	0.010	0.990	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.990	0.010
E53.8 Deficiency of other specified B group vitamins	0.000	0.990	0.010
H34.9 Retinal vascular occlusion, unspecified	0.000	0.990	0.010
H34.1 Central retinal artery occlusion	0.000	0.990	0.009
H34.0 Transient retinal artery occlusion	0.000	0.991	0.009
E66.0 Obesity due to excess calories	0.000	0.991	0.009
G20-G26 Extrapyramidal and movement disorders	0.009	0.991	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.991	0.009
M07.30 Other psoriatic arthropathies (Multiple sites)	0.009	0.991	0.000
E66.1 Drug-induced obesity	0.000	0.991	0.008
M07.39 Other psoriatic arthropathies (Site unspecified)	0.008	0.992	0.000
E78.8 Other disorders of lipoprotein metabolism	0.000	0.992	0.008
M07.3 Other psoriatic arthropathies	0.008	0.992	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.008	0.992	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.992	0.008
E21.3 Hyperparathyroidism, unspecified	0.000	0.992	0.008
J18.0 Bronchopneumonia, unspecified	0.000	0.992	0.008
M47.83 Other spondylosis (Cervicothoracic region)	0.008	0.992	0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.008	0.992	0.000
G21 Secondary Parkinsonism	0.008	0.992	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.008	0.992	0.000
I84.2 Internal haemorrhoids without complication	0.000	0.992	0.008
M47.84 Other spondylosis (Thoracic region)	0.007	0.993	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.007	0.993	0.000
G25 Other extrapyramidal and movement disorders	0.007	0.993	0.000
E78.6 Lipoprotein deficiency	0.000	0.993	0.007
M87.9 Osteonecrosis, unspecified	0.007	0.993	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.007	0.993	0.000
E10-E14 Diabetes mellitus	0.000	0.993	0.007
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.007	0.993	0.000
G23 Other degenerative diseases of basal ganglia	0.007	0.993	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.007	0.993	0.000
G22 Parkinsonism in diseases classified elsewhere	0.007	0.993	0.000
G21.9 Secondary Parkinsonism, unspecified	0.007	0.993	0.000
E78.3 Hyperchylomicronaemia	0.000	0.993	0.006
H34.2 Other retinal artery occlusions	0.000	0.993	0.006
G25.3 Myoclonus	0.007	0.993	0.000
E78.4 Other hyperlipidaemia	0.000	0.993	0.006
M47.86 Other spondylosis (Lumbar region)	0.006	0.994	0.000
M07.38 Other psoriatic arthropathies (Other)	0.006	0.994	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.006	0.994	0.000
M35.0 Sicca syndrome [Sjogren]	0.000	0.994	0.006
G21.1 Other drug-induced secondary Parkinsonism	0.006	0.994	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.006	0.994	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.006	0.994	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.006	0.994	0.000
M87 Osteonecrosis	0.006	0.994	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.006	0.994	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.006	0.994	0.000
G24 Dystonia	0.006	0.994	0.000
G21.8 Other secondary Parkinsonism	0.006	0.994	0.000
G21.4 Vascular parkinsonism	0.006	0.994	0.000
G21.3 Postencephalitic Parkinsonism	0.006	0.994	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.006	0.994	0.000
G21.0 Malignant neuroleptic syndrome	0.006	0.994	0.000
L91.0 Keloid scar	0.006	0.994	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.006	0.994	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.005	0.994	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.005	0.994	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.005	0.994	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.005	0.994	0.000
G25.5 Other chorea	0.005	0.994	0.000
G25.4 Drug-induced chorea	0.005	0.994	0.000
G25.1 Drug-induced tremor	0.005	0.994	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.005	0.995	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.005	0.995	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.005	0.995	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.005	0.995	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.005	0.995	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.005	0.995	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.005	0.995	0.000
E78.1 Pure hyperglyceridaemia	0.000	0.995	0.005
M87.8 Other osteonecrosis	0.005	0.995	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.995	0.005
S82.30 Fracture of lower end of tibia (closed)	0.005	0.995	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.005	0.995	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.005	0.995	0.000
G23.3 Multiple system atrophy, cerebellar type	0.005	0.995	0.000
G23.2 Striatonigral degeneration	0.005	0.995	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.005	0.995	0.000
G23.0 Hallervorden-Spatz disease	0.005	0.995	0.000
M87.2 Osteonecrosis due to previous trauma	0.005	0.995	0.000
G24.3 Spasmodic torticollis	0.005	0.995	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.005	0.995	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.005	0.995	0.000
M87.3 Other secondary osteonecrosis	0.004	0.995	0.000
M87.1 Osteonecrosis due to drugs	0.004	0.995	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.004	0.995	0.000
G25.2 Other specified forms of tremor	0.004	0.995	0.000
G24.5 Blepharospasm	0.004	0.995	0.000
G24.4 Idiopathic orofacial dystonia	0.004	0.996	0.000
G24.2 Idiopathic nonfamilial dystonia	0.004	0.996	0.000
G24.1 Idiopathic familial dystonia	0.004	0.996	0.000
G24.0 Drug-induced dystonia	0.004	0.996	0.000
N43.3 Hydrocele, unspecified	0.004	0.996	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.996	0.004
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.004	0.996	0.000
M87.89 Other osteonecrosis (Site unspecified)	0.004	0.996	0.000
M87.88 Other osteonecrosis (Other)	0.004	0.996	0.000
M87.87 Other osteonecrosis (Ankle and foot)	0.004	0.996	0.000
M87.86 Other osteonecrosis (Lower leg)	0.004	0.996	0.000
M87.84 Other osteonecrosis (Hand)	0.004	0.996	0.000
M87.83 Other osteonecrosis (Forearm)	0.004	0.996	0.000
M87.82 Other osteonecrosis (Upper arm)	0.004	0.996	0.000
M87.81 Other osteonecrosis (Shoulder region)	0.004	0.996	0.000
M87.80 Other osteonecrosis (Multiple sites)	0.004	0.996	0.000
E12.9 Without complications	0.000	0.996	0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations