TreeWAS – Variant ID: rs1233420

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.067	0.933
N40 Hyperplasia of prostate	0.927	0.073	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.083	0.917
N42 Other disorders of prostate	0.913	0.087	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.089	0.911
N42.8 Other specified disorders of prostate	0.908	0.092	0.000
E00-E07 Disorders of thyroid gland	0.000	0.097	0.903
N42.1 Congestion and haemorrhage of prostate	0.889	0.111	0.000
N42.2 Atrophy of prostate	0.875	0.125	0.000
N40-N51 Diseases of male genital organs	0.873	0.127	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.134	0.866
N42.9 Disorder of prostate, unspecified	0.805	0.195	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.219	0.781
N43 Hydrocele and spermatocele	0.733	0.267	0.000
N44 Torsion of testis	0.706	0.293	0.000
E03.5 Myxoedema coma	0.000	0.331	0.669
E03.4 Atrophy of thyroid (acquired)	0.000	0.331	0.669
E03.3 Postinfectious hypothyroidism	0.000	0.331	0.669
E05.5 Thyroid crisis or storm	0.000	0.347	0.653
E05.4 Thyrotoxicosis factitia	0.000	0.347	0.653
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.347	0.653
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.347	0.653
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.353	0.647
E00 Congenital iodine-deficiency syndrome	0.000	0.353	0.647
N42.3 Dysplasia of prostate	0.623	0.377	0.000
N51 Disorders of male genital organs in diseases classified elsewhere	0.619	0.380	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.403	0.597
E06 Thyroiditis	0.000	0.412	0.588
E03.8 Other specified hypothyroidism	0.000	0.415	0.585
N43.2 Other hydrocele	0.575	0.425	0.000
N43.4 Spermatocele	0.565	0.435	0.000
N43.3 Hydrocele, unspecified	0.557	0.443	0.000
N43.1 Infected hydrocele	0.540	0.460	0.000
N43.0 Encysted hydrocele	0.525	0.474	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.489	0.511
E03.1 Congenital hypothyroidism without goitre	0.000	0.490	0.510
N46 Male infertility	0.494	0.505	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.519	0.481
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.475	0.525	0.000
E06.5 Other chronic thyroiditis	0.000	0.526	0.473
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.536	0.464
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.536	0.464
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.536	0.464
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.536	0.464
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.536	0.464
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.536	0.464
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.536	0.464
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.536	0.464
N50 Other disorders of male genital organs	0.452	0.548	0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere	0.444	0.556	0.000
N51.1 Disorders of testis and epididymis in diseases classified elsewhere	0.444	0.556	0.000
N51.0 Disorders of prostate in diseases classified elsewhere	0.444	0.556	0.000
N41 Inflammatory diseases of prostate	0.442	0.558	0.000
N51.2 Balanitis in diseases classified elsewhere	0.437	0.562	0.000
E07 Other disorders of thyroid	0.000	0.577	0.423
E06.4 Drug-induced thyroiditis	0.000	0.578	0.422
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.578	0.422
E06.0 Acute thyroiditis	0.000	0.578	0.422
E83 Disorders of mineral metabolism	0.000	0.579	0.421
N50.9 Disorder of male genital organs, unspecified	0.404	0.596	0.000
E05.8 Other thyrotoxicosis	0.001	0.602	0.397
E06.1 Subacute thyroiditis	0.000	0.605	0.395
E83.5 Disorders of calcium metabolism	0.000	0.611	0.389
E06.3 Autoimmune thyroiditis	0.000	0.621	0.379
E06.9 Thyroiditis, unspecified	0.000	0.635	0.365
K90 Intestinal malabsorption	0.000	0.636	0.364
N45 Orchitis and epididymitis	0.357	0.643	0.000
N41.2 Abscess of prostate	0.350	0.650	0.000
N49.9 Inflammatory disorder of unspecified male genital organ	0.340	0.659	0.000
N49.0 Inflammatory disorders of seminal vesicle	0.340	0.659	0.000
N42.0 Calculus of prostate	0.324	0.675	0.001
N41.8 Other inflammatory diseases of prostate	0.324	0.676	0.000
N41.3 Prostatocystitis	0.317	0.683	0.000
N49.8 Inflammatory disorders of other specified male genital organs	0.315	0.685	0.000
N50.1 Vascular disorders of male genital organs	0.310	0.690	0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens	0.307	0.692	0.000
E07.1 Dyshormogenetic goitre	0.000	0.696	0.303
E07.0 Hypersecretion of calcitonin	0.000	0.696	0.303
E83.8 Other disorders of mineral metabolism	0.000	0.698	0.302
E83.2 Disorders of zinc metabolism	0.000	0.698	0.302
E83.0 Disorders of copper metabolism	0.000	0.698	0.302
N41.0 Acute prostatitis	0.301	0.699	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.717	0.283
N49.2 Inflammatory disorders of scrotum	0.282	0.718	0.000
K90.3 Pancreatic steatorrhoea	0.000	0.739	0.261
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.739	0.261
K90.1 Tropical sprue	0.000	0.739	0.261
G35 Multiple sclerosis	0.000	0.742	0.258
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.743	0.257
K90.8 Other intestinal malabsorption	0.000	0.753	0.247
E07.8 Other specified disorders of thyroid	0.000	0.754	0.245
N41.1 Chronic prostatitis	0.234	0.766	0.000
E83.4 Disorders of magnesium metabolism	0.000	0.775	0.225
E83.3 Disorders of phosphorus metabolism	0.000	0.778	0.222
K90.9 Intestinal malabsorption, unspecified	0.000	0.791	0.209
N41.9 Inflammatory disease of prostate, unspecified	0.208	0.792	0.000
N50.0 Atrophy of testis	0.202	0.798	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.808	0.192
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.191	0.809	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.131	0.869	0.000
M20.1 Hallux valgus (acquired)	0.102	0.898	0.000
K72.9 Hepatic failure, unspecified	0.000	0.899	0.101
E04 Other non-toxic goitre	0.000	0.909	0.091
K72 Hepatic failure, not elsewhere classified	0.000	0.920	0.080
N50.8 Other specified disorders of male genital organs	0.080	0.920	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.929	0.071
K72.0 Acute and subacute hepatic failure	0.000	0.931	0.069
E04.8 Other specified non-toxic goitre	0.000	0.934	0.065
K72.1 Chronic hepatic failure	0.000	0.941	0.059
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.942	0.058
N47 Redundant prepuce, phimosis and paraphimosis	0.055	0.945	0.000
K70-K77 Diseases of liver	0.000	0.952	0.048
K75 Other inflammatory liver diseases	0.000	0.955	0.045
K75.4 Autoimmune hepatitis	0.000	0.958	0.042
G36 Other acute disseminated demyelination	0.000	0.959	0.041
K74 Fibrosis and cirrhosis of liver	0.000	0.960	0.040
C44.3 Skin of other and unspecified parts of face	0.000	0.960	0.040
K75.8 Other specified inflammatory liver diseases	0.000	0.961	0.039
K73 Chronic hepatitis, not elsewhere classified	0.000	0.962	0.038
K74.0 Hepatic fibrosis	0.000	0.964	0.036
K71 Toxic liver disease	0.000	0.964	0.036
K77 Liver disorders in diseases classified elsewhere	0.000	0.965	0.035
K75.9 Inflammatory liver disease, unspecified	0.000	0.967	0.033
K75.2 Nonspecific reactive hepatitis	0.000	0.967	0.033
K75.1 Phlebitis of portal vein	0.000	0.967	0.033
K73.9 Chronic hepatitis, unspecified	0.000	0.967	0.033
M45.X9 Ankylosing spondylitis (Site unspecified)	0.032	0.968	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.969	0.031
K75.0 Abscess of liver	0.000	0.969	0.031
S62.20 Fracture of first metacarpal bone (closed)	0.030	0.970	0.000
G36.9 Acute disseminated demyelination, unspecified	0.000	0.970	0.029
G36.8 Other specified acute disseminated demyelination	0.000	0.970	0.029
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.970	0.029
M20.3 Other deformity of hallux (acquired)	0.030	0.970	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.970	0.030
K74.5 Biliary cirrhosis, unspecified	0.000	0.971	0.029
K74.4 Secondary biliary cirrhosis	0.000	0.971	0.029
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.971	0.029
K74.1 Hepatic sclerosis	0.000	0.971	0.029
K71.0 Toxic liver disease with cholestasis	0.000	0.971	0.029
G36.0 Neuromyelitis optica [Devic]	0.000	0.971	0.029
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.972	0.028
K90-K93 Other diseases of the digestive system	0.000	0.972	0.028
K74.3 Primary biliary cirrhosis	0.000	0.972	0.028
E70-E90 Metabolic disorders	0.000	0.972	0.028
M20 Acquired deformities of fingers and toes	0.028	0.972	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.972	0.027
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.972	0.027
K74.6 Other and unspecified cirrhosis of liver	0.000	0.973	0.027
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.973	0.026
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.974	0.026
K71.9 Toxic liver disease, unspecified	0.000	0.974	0.026
K71.8 Toxic liver disease with other disorders of liver	0.000	0.974	0.026
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.974	0.026
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.974	0.026
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.974	0.026
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.974	0.026
K71.2 Toxic liver disease with acute hepatitis	0.000	0.974	0.026
N48 Other disorders of penis	0.026	0.974	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.974	0.026
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.975	0.025
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.975	0.025
K76.6 Portal hypertension	0.000	0.976	0.024
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.977	0.023
M20.6 Acquired deformity of toe(s), unspecified	0.022	0.978	0.000
K11.5 Sialolithiasis	0.022	0.978	0.000
M45 Ankylosing spondylitis	0.022	0.978	0.000
E89.2 Postprocedural hypoparathyroidism	0.000	0.978	0.022
K76 Other diseases of liver	0.000	0.978	0.022
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.979	0.021
E89.3 Postprocedural hypopituitarism	0.000	0.979	0.021
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.980	0.020
E84 Cystic fibrosis	0.000	0.980	0.020
E76 Disorders of glycosaminoglycan metabolism	0.000	0.980	0.020
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.980	0.020
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.980	0.020
N48.5 Ulcer of penis	0.020	0.980	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.980	0.020
E40-E46 Malnutrition	0.000	0.980	0.020
G37 Other demyelinating diseases of central nervous system	0.001	0.980	0.019
E89.1 Postprocedural hypoinsulinaemia	0.000	0.980	0.019
M89.94 Disorder of bone, unspecified (Hand)	0.020	0.980	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.019	0.981	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.981	0.019
E89.5 Postprocedural testicular hypofunction	0.000	0.981	0.019
E70 Disorders of aromatic amino-acid metabolism	0.000	0.981	0.019
M62.8 Other specified disorders of muscle	0.019	0.981	0.000
M89.9 Disorder of bone, unspecified	0.019	0.981	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.019	0.981	0.000
J38.4 Oedema of larynx	0.000	0.981	0.019
E77 Disorders of glycoprotein metabolism	0.000	0.981	0.018
M62.88 Other specified disorders of muscle (Other)	0.018	0.982	0.000
M89 Other disorders of bone	0.018	0.982	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.018	0.982	0.000
M62 Other disorders of muscle	0.018	0.982	0.000
E74 Other disorders of carbohydrate metabolism	0.000	0.982	0.018
N48.3 Priapism	0.018	0.982	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.982	0.018
E72 Other disorders of amino-acid metabolism	0.000	0.983	0.017
M89.0 Algoneurodystrophy	0.017	0.983	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.983	0.017
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.983	0.017
E89.4 Postprocedural ovarian failure	0.000	0.983	0.017
S62.2 Fracture of first metacarpal bone	0.017	0.983	0.000
E79 Disorders of purine and pyrimidine metabolism	0.000	0.983	0.016
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.017	0.983	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.984	0.016
M89.07 Algoneurodystrophy (Ankle and foot)	0.016	0.984	0.000
J38.3 Other diseases of vocal cords	0.000	0.984	0.016
M35.0 Sicca syndrome [Sjogren]	0.000	0.984	0.016
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.016	0.984	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.016	0.984	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.016	0.984	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.016	0.984	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.016	0.984	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.016	0.984	0.000
N48.1 Balanoposthitis	0.016	0.984	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.984	0.016
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.984	0.015
K76.5 Hepatic veno-occlusive disease	0.000	0.984	0.016
K76.4 Peliosis hepatis	0.000	0.984	0.016
K76.2 Central haemorrhagic necrosis of liver	0.000	0.984	0.016
M45.X6 Ankylosing spondylitis (Lumbar region)	0.015	0.984	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.016	0.984	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.985	0.015
M62.6 Muscle strain	0.015	0.985	0.000
M89.03 Algoneurodystrophy (Forearm)	0.015	0.985	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.015	0.985	0.000
K76.1 Chronic passive congestion of liver	0.000	0.985	0.015
M94.88 Other specified disorders of cartilage (Other)	0.015	0.985	0.000
M89.5 Osteolysis	0.015	0.985	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.985	0.015
K93.1 Megacolon in Chagas' disease	0.000	0.985	0.015
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.985	0.015
N48.6 Balanitis xerotica obliterans	0.015	0.985	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.015	0.985	0.000
M62.4 Contracture of muscle	0.015	0.985	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.015	0.985	0.000
E84.9 Cystic fibrosis, unspecified	0.000	0.985	0.015
E84.8 Cystic fibrosis with other manifestations	0.000	0.985	0.015
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.985	0.015
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.985	0.015
E71.3 Disorders of fatty-acid metabolism	0.000	0.985	0.014
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.985	0.014
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.985	0.014
E71.0 Maple-syrup-urine disease	0.000	0.985	0.014
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.985	0.014
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.985	0.014
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.985	0.014
E76.2 Other mucopolysaccharidoses	0.000	0.985	0.014
E76.1 Mucopolysaccharidosis, type II	0.000	0.985	0.014
E76.0 Mucopolysaccharidosis, type I	0.000	0.985	0.014
N48.9 Disorder of penis, unspecified	0.015	0.985	0.000
M60-M63 Disorders of muscles	0.015	0.985	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.015	0.985	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.014	0.985	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.985	0.014
E45 Retarded development following protein-energy malnutrition	0.000	0.985	0.014
E43 Unspecified severe protein-energy malnutrition	0.000	0.985	0.014
E42 Marasmic kwashiorkor	0.000	0.985	0.014
E41 Nutritional marasmus	0.000	0.985	0.014
E40 Kwashiorkor	0.000	0.985	0.014
G37.5 Concentric sclerosis [Balo]	0.001	0.985	0.014
G37.4 Subacute necrotising myelitis	0.001	0.985	0.014
G37.2 Central pontine myelinolysis	0.001	0.985	0.014
G37.1 Central demyelination of corpus callosum	0.001	0.985	0.014
G37.0 Diffuse sclerosis	0.001	0.985	0.014
R01.1 Cardiac murmur, unspecified	0.014	0.986	0.000
E73 Lactose intolerance	0.001	0.986	0.014
M89.93 Disorder of bone, unspecified (Forearm)	0.014	0.986	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.986	0.014
M89.3 Hypertrophy of bone	0.014	0.986	0.000
J38.7 Other diseases of larynx	0.000	0.986	0.014
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.986	0.014
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.986	0.014
E70.2 Disorders of tyrosine metabolism	0.000	0.986	0.014
E70.1 Other hyperphenylalaninaemias	0.000	0.986	0.014
E70.0 Classical phenylketonuria	0.000	0.986	0.014
E80.1 Porphyria cutanea tarda	0.000	0.986	0.014
K76.7 Hepatorenal syndrome	0.000	0.986	0.014
K70 Alcoholic liver disease	0.000	0.986	0.014
M62.87 Other specified disorders of muscle (Ankle and foot)	0.014	0.986	0.000
M62.0 Diastasis of muscle	0.014	0.986	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.014	0.986	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.014	0.986	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.014	0.986	0.000
M89.04 Algoneurodystrophy (Hand)	0.014	0.986	0.000
J38.2 Nodules of vocal cords	0.000	0.986	0.014
E46 Unspecified protein-energy malnutrition	0.000	0.986	0.014
M45.X2 Ankylosing spondylitis (Cervical region)	0.014	0.986	0.000
M84 Disorders of continuity of bone	0.014	0.986	0.000
K76.3 Infarction of liver	0.000	0.986	0.013
M89.91 Disorder of bone, unspecified (Shoulder region)	0.013	0.986	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.013	0.986	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.986	0.013
E77.1 Defects in glycoprotein degradation	0.000	0.986	0.013
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.986	0.013
M80-M85 Disorders of bone density and structure	0.014	0.986	0.000
M82.1 Osteoporosis in endocrine disorders	0.013	0.986	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.013	0.987	0.000
C50.8 Overlapping lesion of breast	0.013	0.987	0.000
M89.6 Osteopathy after poliomyelitis	0.013	0.987	0.000
M89.2 Other disorders of bone development and growth	0.013	0.987	0.000
M89.1 Epiphyseal arrest	0.013	0.987	0.000
M82 Osteoporosis in diseases classified elsewhere	0.013	0.987	0.000
M62.3 Immobility syndrome (paraplegic)	0.013	0.987	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.013	0.987	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.987	0.013
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.987	0.013
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.987	0.013
E74.2 Disorders of galactose metabolism	0.000	0.987	0.013
E74.1 Disorders of fructose metabolism	0.000	0.987	0.013
M62.2 Ischaemic infarction of muscle	0.013	0.987	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.013	0.987	0.000
M86-M90 Other osteopathies	0.013	0.987	0.000
E70.3 Albinism	0.000	0.987	0.013
E80.2 Other porphyria	0.000	0.987	0.013
M62.1 Other rupture of muscle (nontraumatic)	0.013	0.987	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.013	0.987	0.000
E74.0 Glycogen storage disease	0.000	0.987	0.013
J38.1 Polyp of vocal cord and larynx	0.000	0.987	0.013
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.013	0.987	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.987	0.012
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.987	0.012
E72.5 Disorders of glycine metabolism	0.000	0.987	0.012
E72.4 Disorders of ornithine metabolism	0.000	0.987	0.012
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.987	0.012
E72.2 Disorders of urea cycle metabolism	0.000	0.987	0.012
M62.9 Disorder of muscle, unspecified	0.013	0.987	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.013	0.987	0.000
M89.08 Algoneurodystrophy (Other)	0.013	0.987	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.013	0.987	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.013	0.987	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.013	0.987	0.000
E75.6 Lipid storage disorder, unspecified	0.000	0.987	0.012
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.987	0.012
E75.3 Sphingolipidosis, unspecified	0.000	0.987	0.012
E75.1 Other gangliosidosis	0.000	0.987	0.012
E75.0 GM2 gangliosidosis	0.000	0.987	0.012
M89.98 Disorder of bone, unspecified (Other)	0.012	0.987	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.987	0.012
E80.5 Crigler-Najjar syndrome	0.000	0.987	0.012
E80.3 Defects of catalase and peroxydase	0.000	0.987	0.012
E80.0 Hereditary erythropoietic porphyria	0.000	0.987	0.012
M89.8 Other specified disorders of bone	0.012	0.987	0.000
M85 Other disorders of bone density and structure	0.012	0.987	0.000
S62.21 Fracture of first metacarpal bone (open)	0.012	0.988	0.000
M94.8 Other specified disorders of cartilage	0.012	0.988	0.000
M45-M49 Spondylopathies	0.012	0.988	0.000
M62.46 Contracture of muscle (Lower leg)	0.012	0.988	0.000
M62.65 Muscle strain (Pelvic region and thigh)	0.012	0.988	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.012	0.988	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.012	0.988	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.988	0.012
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.988	0.012
E79.1 Lesch-Nyhan syndrome	0.000	0.988	0.012
M20.5 Other deformities of toe(s) (acquired)	0.012	0.988	0.000
M62.68 Muscle strain (Other)	0.012	0.988	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.988	0.012
M91-M94 Chondropathies	0.012	0.988	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.012	0.988	0.000
M62.66 Muscle strain (Lower leg)	0.012	0.988	0.000
E75.2 Other sphingolipidosis	0.000	0.988	0.012
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.012	0.988	0.000
E77.8 Other disorders of glycoprotein metabolism	0.000	0.988	0.012
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.012	0.988	0.000
M94 Other disorders of cartilage	0.012	0.988	0.000
M62.84 Other specified disorders of muscle (Hand)	0.012	0.988	0.000
M89.56 Osteolysis (Lower leg)	0.012	0.988	0.000
K70.1 Alcoholic hepatitis	0.000	0.988	0.012
M89.06 Algoneurodystrophy (Lower leg)	0.011	0.988	0.000
M99 Biomechanical lesions, not elsewhere classified	0.012	0.988	0.000
E15 Nondiabetic hypoglycaemic coma	0.000	0.988	0.011
J38.5 Laryngeal spasm	0.000	0.988	0.011
N48.0 Leukoplakia of penis	0.011	0.989	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.989	0.011
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.011	0.989	0.000
J38.6 Stenosis of larynx	0.000	0.989	0.011
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.011	0.989	0.000
M84.2 Delayed union of fracture	0.011	0.989	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.011	0.989	0.000
N48.2 Other inflammatory disorders of penis	0.011	0.989	0.000
M62.69 Muscle strain (Site unspecified)	0.011	0.989	0.000
M62.67 Muscle strain (Ankle and foot)	0.011	0.989	0.000
M62.64 Muscle strain (Hand)	0.011	0.989	0.000
M62.63 Muscle strain (Forearm)	0.011	0.989	0.000
M62.62 Muscle strain (Upper arm)	0.011	0.989	0.000
M62.61 Muscle strain (Shoulder region)	0.011	0.989	0.000
M62.60 Muscle strain (Multiple sites)	0.011	0.989	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.011	0.989	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.011	0.989	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.011	0.989	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.011	0.989	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.011	0.989	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.011	0.989	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.011	0.989	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.011	0.989	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.011	0.989	0.000
E86 Volume depletion	0.000	0.989	0.011
M85.6 Other cyst of bone	0.011	0.989	0.000
E72.0 Disorders of amino-acid transport	0.000	0.989	0.011
M89.59 Osteolysis (Site unspecified)	0.011	0.989	0.000
M89.58 Osteolysis (Other)	0.011	0.989	0.000
M89.57 Osteolysis (Ankle and foot)	0.011	0.989	0.000
M89.54 Osteolysis (Hand)	0.011	0.989	0.000
M89.53 Osteolysis (Forearm)	0.011	0.989	0.000
M89.52 Osteolysis (Upper arm)	0.011	0.989	0.000
M89.51 Osteolysis (Shoulder region)	0.011	0.989	0.000
M89.50 Osteolysis (Multiple sites)	0.011	0.989	0.000
E88 Other metabolic disorders	0.000	0.989	0.011
M89.86 Other specified disorders of bone (Lower leg)	0.011	0.989	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.011	0.989	0.000
M62.49 Contracture of muscle (Site unspecified)	0.011	0.989	0.000
M62.48 Contracture of muscle (Other)	0.011	0.989	0.000
M62.47 Contracture of muscle (Ankle and foot)	0.011	0.989	0.000
M62.45 Contracture of muscle (Pelvic region and thigh)	0.011	0.989	0.000
M62.44 Contracture of muscle (Hand)	0.011	0.989	0.000
M62.43 Contracture of muscle (Forearm)	0.011	0.989	0.000
M62.42 Contracture of muscle (Upper arm)	0.011	0.989	0.000
M62.41 Contracture of muscle (Shoulder region)	0.011	0.989	0.000
M62.40 Contracture of muscle (Multiple sites)	0.011	0.989	0.000
M21.3 Wrist or foot drop (acquired)	0.011	0.989	0.000
M62.08 Diastasis of muscle (Other)	0.011	0.989	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.011	0.989	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.011	0.989	0.000
M61 Calcification and ossification of muscle	0.011	0.989	0.000
E75.5 Other lipid storage disorders	0.000	0.989	0.010
E44.1 Mild protein-energy malnutrition	0.000	0.989	0.010
E44.0 Moderate protein-energy malnutrition	0.000	0.989	0.010
E73.8 Other lactose intolerance	0.001	0.989	0.010
E73.1 Secondary lactase deficiency	0.001	0.989	0.010
E73.0 Congenital lactase deficiency	0.001	0.989	0.010
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.010	0.989	0.000
M89.38 Hypertrophy of bone (Other)	0.010	0.989	0.000
M84.3 Stress fracture, not elsewhere classified	0.010	0.989	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.011	0.989	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.010	0.990	0.000
M85.8 Other specified disorders of bone density and structure	0.010	0.990	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.010	0.990	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.010	0.990	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.010	0.990	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.010	0.990	0.000
M89.34 Hypertrophy of bone (Hand)	0.010	0.990	0.000
M89.33 Hypertrophy of bone (Forearm)	0.010	0.990	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.010	0.990	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.010	0.990	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.010	0.990	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.010	0.990	0.000
E80.6 Other disorders of bilirubin metabolism	0.000	0.990	0.010
M85.4 Solitary bone cyst	0.010	0.990	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.010	0.990	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.010	0.990	0.000
M62.09 Diastasis of muscle (Site unspecified)	0.010	0.990	0.000
M62.07 Diastasis of muscle (Ankle and foot)	0.010	0.990	0.000
M62.06 Diastasis of muscle (Lower leg)	0.010	0.990	0.000
M62.05 Diastasis of muscle (Pelvic region and thigh)	0.010	0.990	0.000
M62.04 Diastasis of muscle (Hand)	0.010	0.990	0.000
M62.03 Diastasis of muscle (Forearm)	0.010	0.990	0.000
M62.02 Diastasis of muscle (Upper arm)	0.010	0.990	0.000
M62.01 Diastasis of muscle (Shoulder region)	0.010	0.990	0.000
M62.00 Diastasis of muscle (Multiple sites)	0.010	0.990	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.010	0.990	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.010	0.990	0.000
M84.9 Disorder of continuity of bone, unspecified	0.010	0.990	0.000
M95.2 Other acquired deformity of head	0.010	0.990	0.000
M92 Other juvenile osteochondrosis	0.010	0.990	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.010	0.990	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.010	0.990	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.010	0.990	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.010	0.990	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.010	0.990	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.010	0.990	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.010	0.990	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.010	0.990	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.010	0.990	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.010	0.990	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.010	0.990	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.010	0.990	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.010	0.990	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.010	0.990	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.010	0.990	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.010	0.990	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.010	0.990	0.000
M00-M03 Infectious arthropathies	0.010	0.990	0.000
K76.9 Liver disease, unspecified	0.000	0.990	0.010
M84.8 Other disorders of continuity of bone	0.010	0.990	0.000
M84.0 Malunion of fracture	0.010	0.990	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.010	0.990	0.000
M89.18 Epiphyseal arrest (Other)	0.010	0.990	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.010	0.990	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.010	0.990	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.010	0.990	0.000
M89.14 Epiphyseal arrest (Hand)	0.010	0.990	0.000
M89.13 Epiphyseal arrest (Forearm)	0.010	0.990	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.010	0.990	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.010	0.990	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.010	0.990	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations