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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1233478
log Bayes Factor = 170.338
Chromosome 6   position 29,477,821  (GRCh37) Explore rs1233478 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
N40 Hyperplasia of prostate
0.000 0.000 1.000
R31 Unspecified haematuria
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
D64.9 Anaemia, unspecified
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
E14.3 With ophthalmic complications
0.999 0.001 0.000
E10.1 With ketoacidosis
0.999 0.001 0.000
H30-H36 Disorders of choroid and retina
0.999 0.001 0.000
H36 Retinal disorders in diseases classified elsewhere
0.998 0.002 0.000
H36.0 Diabetic retinopathy
0.998 0.002 0.000
E83.1 Disorders of iron metabolism
0.000 0.002 0.998
H26.9 Cataract, unspecified
0.998 0.002 0.000
H26 Other cataract
0.998 0.002 0.000
H25-H28 Disorders of lens
0.998 0.002 0.000
H43-H45 Disorders of vitreous body and globe
0.997 0.003 0.000
N40-N51 Diseases of male genital organs
0.000 0.003 0.997
E20-E35 Disorders of other endocrine glands
0.995 0.005 0.000
H43 Disorders of vitreous body
0.994 0.006 0.000
E27 Other disorders of adrenal gland
0.992 0.008 0.000
N41 Inflammatory diseases of prostate
0.000 0.008 0.992
I70-I79 Diseases of arteries, arterioles and capillaries
0.992 0.008 0.000
E27.1 Primary adrenocortical insufficiency
0.992 0.008 0.000
I73 Other peripheral vascular diseases
0.991 0.009 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.990 0.010 0.000
M05-M14 Inflammatory polyarthropathies
0.989 0.011 0.000
D80-D89 Certain disorders involving the immune mechanism
0.988 0.012 0.000
I77 Other disorders of arteries and arterioles
0.988 0.012 0.000
I73.9 Peripheral vascular disease, unspecified
0.988 0.012 0.000
E10.2 With renal complications
0.987 0.013 0.000
M06 Other rheumatoid arthritis
0.985 0.015 0.000
D61 Other aplastic anaemias
0.984 0.016 0.000
M06.9 Rheumatoid arthritis, unspecified
0.983 0.017 0.000
H43.1 Vitreous haemorrhage
0.983 0.017 0.000
I77.1 Stricture of artery
0.981 0.019 0.000
E10.4 With neurological complications
0.981 0.019 0.000
D61.9 Aplastic anaemia, unspecified
0.972 0.028 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.971 0.029 0.000
N42 Other disorders of prostate
0.000 0.031 0.969
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.031 0.969
Chapter II Neoplasms
0.965 0.035 0.000
M20-M25 Other joint disorders
0.963 0.037 0.000
C15-C26 Malignant neoplasms of digestive organs
0.962 0.038 0.000
M35 Other systemic involvement of connective tissue
0.962 0.038 0.000
M35.0 Sicca syndrome [Sjogren]
0.960 0.040 0.000
E11 Non-insulin-dependent diabetes mellitus
0.959 0.041 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.955 0.045 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.046 0.954
C25 Malignant neoplasm of pancreas
0.953 0.047 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.950 0.050 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.948 0.052 0.000
E11.9 Without complications
0.948 0.052 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.052 0.948
N45 Orchitis and epididymitis
0.000 0.054 0.946
M15-M19 Arthrosis
0.946 0.054 0.000
I74 Arterial embolism and thrombosis
0.945 0.055 0.000
E14.9 Without complications
0.941 0.059 0.000
E50-E64 Other nutritional deficiencies
0.940 0.060 0.000
N41.1 Chronic prostatitis
0.000 0.065 0.935
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.933 0.067 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.933 0.067 0.000
K40 Inguinal hernia
0.000 0.070 0.930
C15 Malignant neoplasm of oesophagus
0.929 0.071 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.928 0.072 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.926 0.074 0.000
C25.9 Pancreas, unspecified
0.921 0.079 0.000
Chapter IX Diseases of the circulatory system
0.921 0.079 0.000
H26.4 After-cataract
0.919 0.081 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.085 0.915
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.086 0.914
M18 Arthrosis of first carpometacarpal joint
0.913 0.087 0.000
C34 Malignant neoplasm of bronchus and lung
0.911 0.089 0.000
H31 Other disorders of choroid
0.910 0.090 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.908 0.092 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.906 0.094 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.905 0.095 0.000
D50-D53 Nutritional anaemias
0.903 0.097 0.000
N42.9 Disorder of prostate, unspecified
0.000 0.098 0.902
M17 Gonarthrosis [arthrosis of knee]
0.897 0.103 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.896 0.104 0.000
C20 Malignant neoplasm of rectum
0.894 0.106 0.000
C81 Hodgkin's disease
0.893 0.107 0.000
M05 Seropositive rheumatoid arthritis
0.890 0.110 0.000
K40-K46 Hernia
0.001 0.111 0.888
C83 Diffuse non-Hodgkin's lymphoma
0.886 0.114 0.000
E24 Cushing's syndrome
0.882 0.118 0.000
K44 Diaphragmatic hernia
0.000 0.118 0.882
C34.3 Lower lobe, bronchus or lung
0.882 0.118 0.000
N41.0 Acute prostatitis
0.000 0.118 0.882
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.881 0.119 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.880 0.120 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.123 0.877
E13 Other specified diabetes mellitus
0.873 0.127 0.000
M60-M63 Disorders of muscles
0.872 0.128 0.000
M17.9 Gonarthrosis, unspecified
0.870 0.130 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.869 0.131 0.000
C16 Malignant neoplasm of stomach
0.866 0.134 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.864 0.136 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.863 0.137 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.862 0.138 0.000
I73.0 Raynaud's syndrome
0.861 0.139 0.000
C15.9 Oesophagus, unspecified
0.856 0.144 0.000
H31.0 Chorioretinal scars
0.853 0.147 0.000
E11.3 With ophthalmic complications
0.850 0.150 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.847 0.153 0.000
E21.0 Primary hyperparathyroidism
0.847 0.153 0.000
M06.4 Inflammatory polyarthropathy
0.844 0.156 0.000
C83.3 Large cell (diffuse)
0.842 0.158 0.000
N42.1 Congestion and haemorrhage of prostate
0.000 0.160 0.840
E14.8 With unspecified complications
0.837 0.163 0.000
H43.3 Other vitreous opacities
0.837 0.163 0.000
C25.0 Head of pancreas
0.834 0.166 0.000
E21.3 Hyperparathyroidism, unspecified
0.831 0.169 0.000
H43.2 Crystalline deposits in vitreous body
0.831 0.169 0.000
D86 Sarcoidosis
0.829 0.171 0.000
H44 Disorders of globe
0.827 0.173 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.826 0.174 0.000
D51 Vitamin B12 deficiency anaemia
0.824 0.176 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.823 0.177 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.822 0.178 0.000
C69 Malignant neoplasm of eye and adnexa
0.822 0.178 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.821 0.179 0.000
C83.0 Small cell (diffuse)
0.820 0.180 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.820 0.180 0.000
E61 Deficiency of other nutrient elements
0.814 0.186 0.000
C84.5 Other and unspecified T-cell lymphomas
0.813 0.187 0.000
C34.9 Bronchus or lung, unspecified
0.810 0.190 0.000
N42.2 Atrophy of prostate
0.000 0.191 0.809
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.808 0.192 0.000
M31 Other necrotising vasculopathies
0.807 0.193 0.000
H43.9 Disorder of vitreous body, unspecified
0.806 0.194 0.000
M32 Systemic lupus erythematosus
0.805 0.195 0.000
M11 Other crystal arthropathies
0.805 0.195 0.000
E10.7 With multiple complications
0.804 0.196 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.802 0.198 0.000
I70 Atherosclerosis
0.799 0.201 0.000
M35.1 Other overlap syndromes
0.797 0.203 0.000
D83 Common variable immunodeficiency
0.796 0.204 0.000
D84 Other immunodeficiencies
0.793 0.207 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.788 0.212 0.000
C15.4 Middle third of oesophagus
0.787 0.213 0.000
C25.3 Pancreatic duct
0.785 0.215 0.000
E20 Hypoparathyroidism
0.784 0.216 0.000
E14.4 With neurological complications
0.784 0.216 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.784 0.216 0.000
E10.5 With peripheral circulatory complications
0.783 0.217 0.000
E13.9 Without complications
0.782 0.218 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.780 0.220 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.780 0.220 0.000
M15 Polyarthrosis
0.780 0.220 0.000
H52 Disorders of refraction and accommodation
0.778 0.222 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.778 0.222 0.000
K90 Intestinal malabsorption
0.745 0.223 0.031
H30 Chorioretinal inflammation
0.777 0.223 0.000
E10.0 With coma
0.776 0.224 0.000
I77.6 Arteritis, unspecified
0.775 0.225 0.000
E11.5 With peripheral circulatory complications
0.774 0.226 0.000
E53 Deficiency of other B group vitamins
0.774 0.226 0.000
N44 Torsion of testis
0.000 0.228 0.772
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.772 0.228 0.000
D80 Immunodeficiency with predominantly antibody defects
0.771 0.229 0.000
E10.8 With unspecified complications
0.771 0.229 0.000
C84.0 Mycosis fungoides
0.771 0.229 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.231 0.769
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.769 0.231 0.000
C81.2 Mixed cellularity
0.767 0.233 0.000
C85.1 B-cell lymphoma, unspecified
0.766 0.234 0.000
E55 Vitamin D deficiency
0.766 0.234 0.000
K46 Unspecified abdominal hernia
0.000 0.236 0.763
C15.5 Lower third of oesophagus
0.761 0.239 0.000
H52.1 Myopia
0.759 0.241 0.000
E10.6 With other specified complications
0.757 0.243 0.000
M33 Dermatopolymyositis
0.756 0.244 0.000
M12 Other specific arthropathies
0.755 0.245 0.000
C25.8 Overlapping lesion of pancreas
0.754 0.246 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.754 0.246 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.753 0.247 0.000
M35.7 Hypermobility syndrome
0.753 0.247 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.752 0.248 0.000
C25.1 Body of pancreas
0.751 0.249 0.000
E14.2 Withrenal complications
0.751 0.249 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.750 0.250 0.000
E31 Polyglandular dysfunction
0.749 0.251 0.000
E24.2 Drug-induced Cushing's syndrome
0.748 0.252 0.000
C71 Malignant neoplasm of brain
0.745 0.255 0.000
C23 Malignant neoplasm of gallbladder
0.745 0.255 0.000
I73.8 Other specified peripheral vascular diseases
0.743 0.257 0.000
E14.6 With other specified complications
0.741 0.258 0.000
N42.8 Other specified disorders of prostate
0.000 0.259 0.741
D89.1 Cryoglobulinaemia
0.741 0.259 0.000
D50 Iron deficiency anaemia
0.740 0.260 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.739 0.261 0.000
C16.5 Lesser curvature of stomach, unspecified
0.738 0.262 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.738 0.262 0.000
N46 Male infertility
0.000 0.265 0.735
C69.3 Choroid
0.735 0.265 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.734 0.266 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.733 0.267 0.000
C81.0 Lymphocytic predominance
0.733 0.267 0.000
E24.8 Other Cushing's syndrome
0.730 0.270 0.000
C16.6 Greater curvature of stomach, unspecified
0.730 0.270 0.000
D86.9 Sarcoidosis, unspecified
0.729 0.271 0.000
M60 Myositis
0.729 0.271 0.000
H26.1 Traumatic cataract
0.728 0.272 0.000
M17.5 Other secondary gonarthrosis
0.727 0.273 0.000
D55-D59 Haemolytic anaemias
0.727 0.273 0.000
M62 Other disorders of muscle
0.727 0.273 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.726 0.274 0.000
E61.1 Iron deficiency
0.726 0.274 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.724 0.276 0.000
M30 Polyarteritis nodosa and related conditions
0.724 0.276 0.000
M17.1 Other primary gonarthrosis
0.724 0.276 0.000
D61.1 Drug-induced aplastic anaemia
0.723 0.277 0.000
C81.9 Hodgkin's disease, unspecified
0.722 0.278 0.000
Q43 Other congenital malformations of intestine
0.721 0.279 0.000
H52.3 Anisometropia and aniseikonia
0.719 0.281 0.000
E14.1 With ketoacidosis
0.718 0.282 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E14.7 With multiple complications
0.717 0.283 0.000
E14.0 With coma
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
E51 Thiamine deficiency
0.717 0.283 0.000
C04 Malignant neoplasm of floor of mouth
0.716 0.284 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.716 0.284 0.000
M31.6 Other giant cell arteritis
0.716 0.284 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.716 0.284 0.000
H26.3 Drug-induced cataract
0.715 0.285 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.715 0.285 0.000
M13 Other arthritis
0.715 0.285 0.000
H26.2 Complicated cataract
0.714 0.286 0.000
M05.8 Other seropositive rheumatoid arthritis
0.714 0.286 0.000
C31 Malignant neoplasm of accessory sinuses
0.713 0.287 0.000
C34.0 Main bronchus
0.713 0.287 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.713 0.287 0.000
E32 Diseases of thymus
0.713 0.287 0.000
E30 Disorders of puberty, not elsewhere classified
0.713 0.287 0.000
E25 Adrenogenital disorders
0.713 0.287 0.000
H43.0 Vitreous prolapse
0.712 0.288 0.000
H44.2 Degenerative myopia
0.712 0.288 0.000
K50-K52 Noninfective enteritis and colitis
0.010 0.288 0.701
E27.5 Adrenomedullary hyperfunction
0.711 0.288 0.000
E27.0 Other adrenocortical overactivity
0.711 0.288 0.000
K50 Crohn's disease [regional enteritis]
0.000 0.289 0.711
M35.3 Polymyalgia rheumatica
0.711 0.289 0.000
N41.3 Prostatocystitis
0.000 0.289 0.711
N41.2 Abscess of prostate
0.000 0.289 0.711
M22 Disorders of patella
0.710 0.290 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.709 0.291 0.000
M08 Juvenile arthritis
0.709 0.291 0.000
I74.5 Embolism and thrombosis of iliac artery
0.709 0.291 0.000
D82 Immunodeficiency associated with other major defects
0.708 0.291 0.000
D81 Combined immunodeficiencies
0.708 0.291 0.000
I77.5 Necrosis of artery
0.708 0.291 0.000
I77.4 Coeliac artery compression syndrome
0.708 0.291 0.000
I77.3 Arterial fibromuscular dysplasia
0.708 0.291 0.000
C38.4 Pleura
0.708 0.292 0.000
C95 Leukaemia of unspecified cell type
0.708 0.292 0.000
M06.8 Other specified rheumatoid arthritis
0.706 0.294 0.000
M06.2 Rheumatoid bursitis
0.706 0.294 0.000
M06.1 Adult-onset Still's disease
0.706 0.294 0.000
D61.8 Other specified aplastic anaemias
0.706 0.294 0.000
D61.3 Idiopathic aplastic anaemia
0.706 0.294 0.000
D61.2 Aplastic anaemia due to other external agents
0.706 0.294 0.000
D61.0 Constitutional aplastic anaemia
0.706 0.294 0.000
N48 Other disorders of penis
0.000 0.294 0.706
M00-M03 Infectious arthropathies
0.705 0.295 0.000
C15.0 Cervical part of oesophagus
0.705 0.295 0.000
I00-I02 Acute rheumatic fever
0.703 0.297 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.703 0.297 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.702 0.297 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.702 0.298 0.000
C70 Malignant neoplasm of meninges
0.702 0.298 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.702 0.298 0.000
H44.0 Purulent endophthalmitis
0.699 0.301 0.000
E14.5 With peripheral circulatory complications
0.699 0.301 0.000
M24 Other specific joint derangements
0.699 0.301 0.000
K51 Ulcerative colitis
0.000 0.301 0.698
Q80-Q89 Other congenital malformations
0.698 0.302 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.697 0.302 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.697 0.303 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.696 0.304 0.000
N42.3 Dysplasia of prostate
0.000 0.305 0.694
C88 Malignant immunoproliferative diseases
0.693 0.307 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.693 0.307 0.000
E07 Other disorders of thyroid
0.693 0.307 0.000
I77.8 Other specified disorders of arteries and arterioles
0.692 0.308 0.000
E06 Thyroiditis
0.691 0.309 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.690 0.310 0.000
M14 Arthropathies in other diseases classified elsewhere
0.690 0.310 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.689 0.310 0.000
M35.8 Other specified systemic involvement of connective tissue
0.689 0.310 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.689 0.310 0.000
M35.5 Multifocal fibrosclerosis
0.689 0.310 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.689 0.310 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.689 0.311 0.000
E11.7 With multiple complications
0.688 0.312 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.687 0.313 0.000
C81.1 Nodular sclerosis
0.686 0.314 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.685 0.314 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.685 0.315 0.000
C94 Other leukaemias of specified cell type
0.685 0.315 0.000
C86 Other specified types of T/NK-cell lymphoma
0.685 0.315 0.000
D50.8 Other iron deficiency anaemias
0.684 0.316 0.000
C25.7 Other parts of pancreas
0.683 0.316 0.000
C25.4 Endocrine pancreas
0.683 0.316 0.000
H31.3 Choroidal haemorrhage and rupture
0.683 0.317 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.683 0.317 0.000
H43.8 Other disorders of vitreous body
0.682 0.318 0.000
E03.8 Other specified hypothyroidism
0.682 0.318 0.000
M07 Psoriatic and enteropathic arthropathies
0.681 0.319 0.000
Q39 Congenital malformations of oesophagus
0.681 0.319 0.000
K50.9 Crohn's disease, unspecified
0.000 0.319 0.681
K50.0 Crohn's disease of small intestine
0.000 0.320 0.680
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.320 0.680
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.680 0.320 0.000
D89.3 Immune reconstitution syndrome
0.680 0.320 0.000
E11.1 With ketoacidosis
0.680 0.320 0.000
E05.8 Other thyrotoxicosis
0.679 0.321 0.000
E27.9 Disorder of adrenal gland, unspecified
0.678 0.321 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.677 0.323 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.677 0.323 0.000
C13 Malignant neoplasm of hypopharynx
0.675 0.325 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.674 0.326 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.674 0.326 0.000
E63 Other nutritional deficiencies
0.674 0.326 0.000
E56 Other vitamin deficiencies
0.674 0.326 0.000
E50 Vitamin A deficiency
0.674 0.326 0.000
E60 Dietary zinc deficiency
0.674 0.326 0.000
E59 Dietary selenium deficiency
0.674 0.326 0.000
E58 Dietary calcium deficiency
0.674 0.326 0.000
E54 Ascorbic acid deficiency
0.674 0.326 0.000
E52 Niacin deficiency [pellagra]
0.674 0.326 0.000
K51.2 Ulcerative (chronic) proctitis
0.000 0.327 0.673
Q45 Other congenital malformations of digestive system
0.673 0.327 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.329 0.671
M18.1 Other primary arthrosis of first carpometacarpal joint
0.670 0.330 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.669 0.331 0.000
E21.4 Other specified disorders of parathyroid gland
0.669 0.331 0.000
E21.2 Other hyperparathyroidism
0.669 0.331 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.669 0.331 0.000
C33 Malignant neoplasm of trachea
0.669 0.331 0.000
E11.0 With coma
0.669 0.331 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.333 0.667
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.333 0.667
Q38 Other congenital malformations of tongue, mouth and pharynx
0.667 0.333 0.000
C15.8 Overlapping lesion of oesophagus
0.666 0.334 0.000
C15.2 Abdominal part of oesophagus
0.666 0.334 0.000
C15.1 Thoracic part of oesophagus
0.666 0.334 0.000
N48.4 Impotence of organic origin
0.000 0.334 0.666
D86.0 Sarcoidosis of lung
0.665 0.335 0.000
I79.1 Aortitis in diseases classified elsewhere
0.665 0.335 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.665 0.335 0.000
M15.8 Other polyarthrosis
0.665 0.335 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.665 0.335 0.000
M34 Systemic sclerosis
0.664 0.336 0.000
C16.8 Overlapping lesion of stomach
0.664 0.336 0.000
Chapter XI Diseases of the digestive system
0.069 0.337 0.594
E27.2 Addisonian crisis
0.662 0.337 0.000
C37 Malignant neoplasm of thymus
0.662 0.338 0.000
I74.8 Embolism and thrombosis of other arteries
0.662 0.338 0.000
C69.9 Eye, unspecified
0.661 0.339 0.000
C84.4 Peripheral T-cell lymphoma
0.661 0.339 0.000
C71.1 Frontal lobe
0.660 0.340 0.000
M11.2 Other chondrocalcinosis
0.660 0.340 0.000
E24.0 Pituitary-dependent Cushing's disease
0.659 0.341 0.000
K50.8 Other Crohn's disease
0.000 0.341 0.659
Q00-Q07 Congenital malformations of the nervous system
0.659 0.341 0.000
I77.2 Rupture of artery
0.659 0.341 0.000
Q40 Other congenital malformations of upper alimentary tract
0.658 0.342 0.000
D83.9 Common variable immunodeficiency, unspecified
0.658 0.342 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.657 0.343 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.657 0.343 0.000
Q44.5 Other congenital malformations of bile ducts
0.656 0.344 0.000
M13.0 Polyarthritis, unspecified
0.656 0.344 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.654 0.346 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.654 0.346 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.654 0.346 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.654 0.346 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.654 0.346 0.000
K51.4 Pseudopolyposis of colon
0.000 0.346 0.654
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.653 0.347 0.000
C34.8 Overlapping lesion of bronchus and lung
0.653 0.347 0.000
M10 Gout
0.653 0.347 0.000
H31.9 Disorder of choroid, unspecified
0.652 0.348 0.000
H31.4 Choroidal detachment
0.652 0.348 0.000
H31.2 Hereditary choroidal dystrophy
0.652 0.348 0.000
C93 Monocytic leukaemia
0.652 0.348 0.000
E11.8 With unspecified complications
0.651 0.349 0.000
C84.9 Mature T/NK-cell lymphoma, unspecified
0.651 0.349 0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.651 0.349 0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.651 0.349 0.000
C84.3 Lymphoepithelioid lymphoma
0.651 0.349 0.000
C84.2 T-zone lymphoma
0.651 0.349 0.000
C84.1 Sezary's diease
0.651 0.349 0.000
D53 Other nutritional anaemias
0.651 0.349 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.650 0.350 0.000
Q35-Q37 Cleft lip and cleft palate
0.649 0.351 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.649 0.351 0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.000 0.351 0.649
C30 Malignant neoplasm of nasal cavity and middle ear
0.648 0.352 0.000
Q74 Other congenital malformations of limb(s)
0.648 0.352 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.647 0.353 0.000
M22.2 Patellofemoral disorders
0.644 0.356 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.643 0.357 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.643 0.357 0.000
E16.1 Other hypoglycaemia
0.643 0.357 0.000
C85.0 Lymphosarcoma
0.643 0.357 0.000
E55.9 Vitamin D deficiency, unspecified
0.641 0.359 0.000
N48.1 Balanoposthitis
0.000 0.359 0.641
C81.7 Other Hodgkin's disease
0.640 0.359 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.640 0.359 0.000
C81.3 Lymphocytic depletion
0.640 0.359 0.000
C15.3 Upper third of oesophagus
0.640 0.360 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.640 0.360 0.000
H31.8 Other specified disorders of choroid
0.638 0.362 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.624 0.362 0.014
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.638 0.362 0.000
M05.2 Rheumatoid vasculitis
0.638 0.362 0.000
M05.1 Rheumatoid lung disease
0.638 0.362 0.000
M05.0 Felty's syndrome
0.638 0.362 0.000
C16.2 Body of stomach
0.637 0.363 0.000
D84.9 Immunodeficiency, unspecified
0.637 0.363 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.636 0.364 0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.000 0.364 0.635
I70.8 Atherosclerosis of other arteries
0.635 0.365 0.000
C83.6 Undifferentiated (diffuse)
0.635 0.365 0.000
C83.5 Lymphoblastic (diffuse)
0.635 0.365 0.000
C83.4 Immunoblastic (diffuse)
0.635 0.365 0.000
C83.2 Mixed small and large cell (diffuse)
0.635 0.365 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.633 0.367 0.000
E20.9 Hypoparathyroidism, unspecified
0.633 0.367 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.633 0.367 0.000
E24.3 Ectopic ACTH syndrome
0.633 0.367 0.000
E24.1 Nelson's syndrome
0.633 0.367 0.000
K44.1 Diaphragmatic hernia with gangrene
0.000 0.367 0.632
Q44.6 Cystic disease of liver
0.631 0.369 0.000
C04.0 Anterior floor of mouth
0.631 0.369 0.000
C03 Malignant neoplasm of gum
0.630 0.370 0.000
E53.8 Deficiency of other specified B group vitamins
0.628 0.372 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.627 0.373 0.000
M06.3 Rheumatoid nodule
0.626 0.374 0.000
E13.8 With unspecified complications
0.626 0.374 0.000
E13.7 With multiple complications
0.626 0.374 0.000
E13.6 With other specified complications
0.626 0.374 0.000
E13.5 With peripheral circulatory complications
0.626 0.374 0.000
E13.4 With neurological complications
0.626 0.374 0.000
E13.3 With ophthalmic complications
0.626 0.374 0.000
E13.2 With renal complications
0.626 0.374 0.000
E13.1 With ketoacidosis
0.626 0.374 0.000
E13.0 With coma
0.626 0.374 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.625 0.375 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.625 0.375 0.000
M61 Calcification and ossification of muscle
0.625 0.375 0.000
C16.0 Cardia
0.624 0.375 0.000
C01 Malignant neoplasm of base of tongue
0.624 0.376 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.624 0.376 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.623 0.377 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.623 0.377 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.621 0.379 0.000
C16.4 Pylorus
0.621 0.379 0.000
C16.1 Fundus of stomach
0.621 0.379 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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