TreeWAS – Variant ID: rs12356580

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter XX External causes of morbidity and mortality	1.000	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.999	0.001
# Top node	0.999	0.001
Chapter X Diseases of the respiratory system	0.998	0.002
S40-S49 Injuries to the shoulder and upper arm	0.995	0.005
S20-S29 Injuries to the thorax	0.991	0.009
J40-J47 Chronic lower respiratory diseases	0.991	0.009
Y44 Agents primarily affecting blood constituents	0.984	0.016
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.983	0.017
J09-J18 Influenza and pneumonia	0.982	0.018
T66-T78 Other and unspecified effects of external causes	0.979	0.021
S42 Fracture of shoulder and upper arm	0.972	0.028
Y44.2 Anticoagulants	0.971	0.029
S22 Fracture of rib(s), sternum and thoracic spine	0.969	0.031
S00-S09 Injuries to the head	0.966	0.034
J40 Bronchitis, not specified as acute or chronic	0.963	0.037
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.957	0.043
Chapter II Neoplasms	0.952	0.048
T78 Adverse effects, not elsewhere classified	0.947	0.053
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.939	0.061
S49 Other and unspecified injuries of shoulder and upper arm	0.933	0.067
T36-T50 Poisoning by drugs, medicaments and biological substances	0.931	0.069
S42.2 Fracture of upper end of humerus	0.928	0.072
S01 Open wound of head	0.927	0.073
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.922	0.078
S22.3 Fracture of rib	0.922	0.078
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.916	0.084
Y86 Sequelae of other accidents	0.913	0.087
Chapter V Mental and behavioural disorders	0.910	0.090
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.904	0.096
Chapter IV Endocrine, nutritional and metabolic diseases	0.903	0.097
Y95 Nosocomial condition	0.902	0.098
S22.0 Fracture of thoracic vertebra	0.899	0.101
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.898	0.102
S42.20 Fracture of upper end of humerus (closed)	0.897	0.103
J14 Pneumonia due to Haemophilus influenzae	0.894	0.106
E70-E90 Metabolic disorders	0.892	0.108
J44 Other chronic obstructive pulmonary disease	0.889	0.111
S49.9 Unspecified injury of shoulder and upper arm	0.888	0.112
S22.30 Fracture of rib (closed)	0.888	0.112
C15-C26 Malignant neoplasms of digestive organs	0.885	0.115
J18 Pneumonia, organism unspecified	0.885	0.115
Y45.1 Salicylates	0.884	0.116
F30-F39 Mood [affective] disorders	0.884	0.116
Chapter XXII Codes for special purposes	0.882	0.118
T78.2 Anaphylactic shock, unspecified	0.882	0.118
S42.3 Fracture of shaft of humerus	0.881	0.119
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.876	0.124
C45 Mesothelioma	0.872	0.128
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.867	0.133
Y48 Anaesthetics and therapeutic gases	0.866	0.134
E83 Disorders of mineral metabolism	0.865	0.135
S01.8 Open wound of other parts of head	0.864	0.136
T00-T07 Injuries involving multiple body regions	0.860	0.140
C92 Myeloid leukaemia	0.853	0.147
X60-X84 Intentional self-harm	0.852	0.148
F31 Bipolar affective disorder	0.850	0.150
S01.5 Open wound of lip and oral cavity	0.849	0.151
S22.00 Fracture of thoracic vertebra (closed)	0.849	0.151
E83.1 Disorders of iron metabolism	0.846	0.154
C20 Malignant neoplasm of rectum	0.845	0.155
V01-V09 Pedestrian injured in transport accident	0.844	0.156
E87 Other disorders of fluid, electrolyte and acid-base balance	0.841	0.159
F33 Recurrent depressive disorder	0.840	0.160
J90-J94 Other diseases of pleura	0.835	0.165
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.834	0.166
S80-S89 Injuries to the knee and lower leg	0.829	0.171
S27 Injury of other and unspecified intrathoracic organs	0.828	0.172
E40-E46 Malnutrition	0.828	0.172
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.827	0.173
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.827	0.173
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.824	0.176
T68 Hypothermia	0.823	0.177
S20 Superficial injury of thorax	0.823	0.177
E87.1 Hypo-osmolality and hyponatraemia	0.821	0.179
S01.2 Open wound of nose	0.821	0.179
S09 Other and unspecified injuries of head	0.820	0.180
Y46 Antiepileptics and anti-Parkinsonism drugs	0.820	0.180
C71 Malignant neoplasm of brain	0.819	0.181
S06 Intracranial injury	0.818	0.182
S42.30 Fracture of shaft of humerus (closed)	0.817	0.183
F31.9 Bipolar affective disorder, unspecified	0.815	0.185
C92.0 Acute myeloid leukaemia	0.813	0.187
C45.0 Mesothelioma of pleura	0.811	0.189
T20-T25 Burns and corrosions of external body surface, specified by site	0.810	0.190
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.810	0.190
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.810	0.190
T78.1 Other adverse food reactions, not elsewhere classified	0.809	0.191
W75-W84 Other accidental threats to breathing	0.808	0.192
S90-S99 Injuries to the ankle and foot	0.807	0.193
S40 Superficial injury of shoulder and upper arm	0.807	0.193
Y91 Evidence of alcohol involvement determined by level of intoxication	0.806	0.194
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.805	0.195
J15 Bacterial pneumonia, not elsewhere classified	0.804	0.196
J47 Bronchiectasis	0.801	0.199
C64-C68 Malignant neoplasms of urinary tract	0.796	0.204
S82 Fracture of lower leg, including ankle	0.794	0.206
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.792	0.208
Chapter I Certain infectious and parasitic diseases	0.791	0.209
J95-J99 Other diseases of the respiratory system	0.791	0.209
S21 Open wound of thorax	0.788	0.212
Y52 Agents primarily affecting the cardiovascular system	0.788	0.212
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.788	0.212
Y53 Agents primarily affecting the gastro-intestinal system	0.786	0.214
E88 Other metabolic disorders	0.786	0.214
F33.1 Recurrent depressive disorder, current episode moderate	0.781	0.219
T66 Unspecified effects of radiation	0.778	0.221
S10-S19 Injuries to the neck	0.777	0.222
C04 Malignant neoplasm of floor of mouth	0.776	0.224
T78.4 Allergy, unspecified	0.776	0.224
F40-F48 Neurotic, stress-related and somatoform disorders	0.776	0.224
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.775	0.225
S41 Open wound of shoulder and upper arm	0.775	0.225
E46 Unspecified protein-energy malnutrition	0.775	0.225
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.773	0.227
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.772	0.228
Y60-Y69 Misadventures to patients during surgical and medical care	0.772	0.228
E83.4 Disorders of magnesium metabolism	0.772	0.228
J46 Status asthmaticus	0.771	0.229
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.769	0.231
J10 Influenza due to identified influenza virus	0.768	0.232
Y45.0 Opioids and related analgesics	0.767	0.233
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.767	0.233
V80-V89 Other land transport accidents	0.767	0.233
J92 Pleural plaque	0.766	0.234
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.765	0.235
S46 Injury of muscle and tendon at shoulder and upper arm level	0.765	0.235
Y45.8 Other analgesics and antipyretics	0.765	0.235
J44.8 Other specified chronic obstructive pulmonary disease	0.765	0.235
J42 Unspecified chronic bronchitis	0.763	0.237
E86 Volume depletion	0.762	0.238
E87.0 Hyperosmolality and hypernatraemia	0.762	0.238
C45.9 Mesothelioma, unspecified	0.760	0.240
S22.1 Multiple fractures of thoracic spine	0.760	0.240
E87.5 Hyperkalaemia	0.760	0.240
S00 Superficial injury of head	0.759	0.241
C25 Malignant neoplasm of pancreas	0.757	0.243
C22.0 Liver cell carcinoma	0.756	0.244
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.756	0.244
T42.4 Benzodiazepines	0.754	0.246
J18.0 Bronchopneumonia, unspecified	0.754	0.246
X40-X49 Accidental poisoning by and exposure to noxious substances	0.753	0.247
Y44.5 Thrombolytic drugs	0.752	0.248
J13 Pneumonia due to Streptococcus pneumoniae	0.752	0.248
J45 Asthma	0.750	0.250
F80-F89 Disorders of psychological development	0.749	0.251
Y84.6 Urinary catheterisation	0.749	0.251
S42.9 Fracture of shoulder girdle, part unspecified	0.749	0.251
F41 Other anxiety disorders	0.748	0.252
C09 Malignant neoplasm of tonsil	0.747	0.252
S09.9 Unspecified injury of head	0.747	0.253
Y48.3 Local anaesthetics	0.746	0.254
T79-T79 Certain early complications of trauma	0.743	0.257
Y54.4 Loop [high-ceiling] diuretics	0.742	0.257
W20-W49 Exposure to inanimate mechanical forces	0.741	0.259
F41.2 Mixed anxiety and depressive disorder	0.740	0.260
V95-V97 Air and space transport accidents	0.740	0.260
C71.0 Cerebrum, except lobes and ventricles	0.740	0.260
C40-C41 Malignant neoplasms of bone and articular cartilage	0.739	0.261
C83 Diffuse non-Hodgkin's lymphoma	0.739	0.261
C71.9 Brain, unspecified	0.736	0.264
A30-A49 Other bacterial diseases	0.734	0.266
S90 Superficial injury of ankle and foot	0.732	0.268
S01.9 Open wound of head, part unspecified	0.729	0.271
Y40 Systemic antibiotics	0.728	0.272
U88 Agent resistant to multiple antibiotics	0.728	0.272
V70-V79 Bus occupant injured in transport accident	0.727	0.272
Y57 Other and unspecified drugs and medicaments	0.727	0.273
J92.9 Pleural plaque without asbestos	0.724	0.276
J18.1 Lobar pneumonia, unspecified	0.724	0.276
B15-B19 Viral hepatitis	0.723	0.277
J11 Influenza, virus not identified	0.723	0.277
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.722	0.278
E50-E64 Other nutritional deficiencies	0.721	0.279
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.721	0.279
T70 Effects of air pressure and water pressure	0.721	0.279
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.720	0.280
Y49 Psychotropic drugs, not elsewhere classified	0.720	0.280
S27.0 Traumatic pneumothorax	0.718	0.281
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.718	0.282
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
Y35-Y36 Legal intervention and operations of war	0.717	0.283
Y10-Y34 Event of undetermined intent	0.717	0.283
X85-X99 Assault	0.717	0.283
X30-X39 Exposure to forces of nature	0.717	0.283
X00-X09 Exposure to smoke, fire and flames	0.717	0.283
W65-W74 Accidental drowning and submersion	0.717	0.283
V90-V94 Water transport accidents	0.717	0.283
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.717	0.283
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.717	0.283
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.717	0.283
Y59 Other and unspecified vaccines and biological substances	0.717	0.283
Y58 Bacterial vaccines	0.717	0.283
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.717	0.283
Y50 Central nervous system stimulants, not elsewhere classified	0.717	0.283
Y47 Sedatives, hypnotics and antianxiety drugs	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.716	0.284
W00-W19 Falls	0.716	0.284
C49 Malignant neoplasm of other connective and soft tissue	0.716	0.284
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.715	0.285
S48 Traumatic amputation of shoulder and upper arm	0.714	0.286
S45 Injury of blood vessels at shoulder and upper arm level	0.714	0.286
S44 Injury of nerves at shoulder and upper arm level	0.714	0.286
S47 Crushing injury of shoulder and upper arm	0.714	0.286
T42.1 Iminostilbenes	0.713	0.287
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.713	0.287
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.711	0.289
S26 Injury of heart	0.711	0.289
S25 Injury of blood vessels of thorax	0.711	0.289
S24 Injury of nerves and spinal cord at thorax level	0.711	0.289
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.711	0.289
T46 Poisoning by agents primarily affecting the cardiovascular system	0.711	0.289
J41 Simple and mucopurulent chronic bronchitis	0.710	0.289
C16 Malignant neoplasm of stomach	0.709	0.291
V20-V29 Motorcycle rider injured in transport accident	0.709	0.291
B95-B98 Bacterial, viral and other infectious agents	0.708	0.292
J17 Pneumonia in diseases classified elsewhere	0.707	0.293
V98-V99 Other and unspecified transport accidents	0.706	0.294
Y44.9 Other and unspecified agents affecting blood constituents	0.706	0.294
Y44.7 Plasma substitutes	0.706	0.294
Y44.6 Natural blood and blood products	0.706	0.294
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.706	0.294
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.706	0.294
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.706	0.294
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.706	0.294
S42.1 Fracture of scapula	0.705	0.295
S82.6 Fracture of lateral malleolus	0.705	0.295
Y45.4 Antirheumatics	0.705	0.295
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.704	0.296
J09 Influenza due to certain identified influenza virus	0.704	0.296
F33.0 Recurrent depressive disorder, current episode mild	0.704	0.296
Y00-Y09 Assault	0.702	0.298
T74 Maltreatment syndromes	0.702	0.298
T73 Effects of other deprivation	0.702	0.298
T69 Other effects of reduced temperature	0.702	0.298
T67 Effects of heat and light	0.702	0.298
T71 Asphyxiation	0.702	0.298
V04 Pedestrian injured in collision with heavy transport vehicle or bus	0.702	0.298
J12 Viral pneumonia, not elsewhere classified	0.700	0.300
X50-X57 Overexertion, travel and privation	0.700	0.300
C22.9 Liver, unspecified	0.699	0.301
S70-S79 Injuries to the hip and thigh	0.699	0.301
Y91.9 Alcohol involvement, not otherwise specified	0.698	0.302
C10 Malignant neoplasm of oropharynx	0.698	0.302
F33.9 Recurrent depressive disorder, unspecified	0.697	0.303
S42.8 Fracture of other parts of shoulder and upper arm	0.697	0.303
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.696	0.304
S82.7 Multiple fractures of lower leg	0.696	0.304
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.695	0.304
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.695	0.305
S86 Injury of muscle and tendon at lower leg level	0.695	0.305
X10-X19 Contact with heat and hot substances	0.695	0.305
S22.9 Fracture of bony thorax, part unspecified	0.694	0.306
S22.8 Fracture of other parts of bony thorax	0.694	0.306
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.694	0.306
T40.4 Other synthetic narcotics	0.694	0.306
Y46.4 Iminostilbenes	0.693	0.307
S08 Traumatic amputation of part of head	0.692	0.308
S07 Crushing injury of head	0.692	0.308
S04 Injury of cranial nerves	0.692	0.308
S03 Dislocation, sprain and strain of joints and ligaments of head	0.692	0.308
Y45.2 Propionic acid derivatives	0.692	0.308
C85.1 B-cell lymphoma, unspecified	0.691	0.309
S29 Other and unspecified injuries of thorax	0.691	0.309
T00 Superficial injuries involving multiple body regions	0.691	0.309
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.691	0.309
S01.4 Open wound of cheek and temporomandibular area	0.691	0.309
C03 Malignant neoplasm of gum	0.690	0.310
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.690	0.310
T78.8 Other adverse effects, not elsewhere classified	0.689	0.311
C04.9 Floor of mouth, unspecified	0.689	0.311
T78.3 Angioneurotic oedema	0.688	0.312
T02 Fractures involving multiple body regions	0.688	0.312
C05 Malignant neoplasm of palate	0.687	0.313
T91 Sequelae of injuries of neck and trunk	0.687	0.313
C01 Malignant neoplasm of base of tongue	0.686	0.314
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.686	0.314
Y98 Lifestyle-related condition	0.686	0.314
Y97 Environmental-pollution-related condition	0.686	0.314
Y96 Work-related condition	0.686	0.314
Y89 Sequelae of other external causes	0.685	0.314
F31.7 Bipolar affective disorder, currently in remission	0.685	0.315
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.684	0.315
Y41 Other systemic anti-infectives and antiparasitics	0.680	0.319
F70-F79 Mental retardation	0.679	0.320
T78.9 Adverse effect, unspecified	0.679	0.321
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.679	0.321
J18.9 Pneumonia, unspecified	0.679	0.321
S20.2 Contusion of thorax	0.678	0.322
B18 Chronic viral hepatitis	0.677	0.323
S06.4 Epidural haemorrhage	0.677	0.323
C21 Malignant neoplasm of anus and anal canal	0.675	0.324
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.673	0.327
C93 Monocytic leukaemia	0.672	0.327
S82.4 Fracture of fibula alone	0.672	0.328
Y54.3 Benzothiadiazine derivatives	0.671	0.329
S42.7 Multiple fractures of clavicle, scapula and humerus	0.670	0.329
Y48.4 Anaesthetic, unspecified	0.669	0.331
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.669	0.331
S49.8 Other specified injuries of shoulder and upper arm	0.669	0.331
S49.7 Multiple injuries of shoulder and upper arm	0.669	0.331
S82.3 Fracture of lower end of tibia	0.668	0.332
Y84.2 Radiological procedure and radiotherapy	0.667	0.333
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.667	0.333
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.667	0.333
T41 Poisoning by anaesthetics and therapeutic gases	0.667	0.333
C45.7 Mesothelioma of other sites	0.667	0.333
C64 Malignant neoplasm of kidney, except renal pelvis	0.666	0.334
J98 Other respiratory disorders	0.666	0.334
S42.21 Fracture of upper end of humerus (open)	0.665	0.335
A40 Streptococcal septicaemia	0.665	0.335
U89 Agent resistant to other and unspecified antibiotics	0.664	0.336
T36 Poisoning by systemic antibiotics	0.664	0.336
V40-V49 Car occupant injured in transport accident	0.663	0.337
S06.3 Focal brain injury	0.662	0.337
S42.4 Fracture of lower end of humerus	0.662	0.338
J15.9 Bacterial pneumonia, unspecified	0.662	0.338
J94 Other pleural conditions	0.662	0.338
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.661	0.339
J00-J06 Acute upper respiratory infections	0.661	0.339
S22.31 Fracture of rib (open)	0.661	0.339
W10 Fall on and from stairs and steps	0.661	0.339
Y45.5 4-Aminophenol derivatives	0.659	0.341
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.658	0.342
C84 Peripheral and cutaneous T-cell lymphomas	0.657	0.343
T01 Open wounds involving multiple body regions	0.657	0.343
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.657	0.343
C94 Other leukaemias of specified cell type	0.657	0.343
C86 Other specified types of T/NK-cell lymphoma	0.657	0.343
V01 Pedestrian injured in collision with pedal cycle	0.656	0.343
S22.5 Flail chest	0.656	0.343
Y84.4 Aspiration of fluid	0.656	0.343
X68 Intentional self-poisoning by and exposure to pesticides	0.656	0.344
S90.9 Superficial injury of ankle and foot, unspecified	0.655	0.344
S82.1 Fracture of upper end of tibia	0.655	0.345
S01.3 Open wound of ear	0.654	0.346
X58-X59 Accidental exposure to other and unspecified factors	0.654	0.346
C95 Leukaemia of unspecified cell type	0.654	0.346
X20-X29 Contact with venomous animals and plants	0.654	0.346
C23 Malignant neoplasm of gallbladder	0.654	0.346
E53 Deficiency of other B group vitamins	0.654	0.346
B97 Viral agents as the cause of diseases classified to other chapters	0.654	0.346
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.653	0.347
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.653	0.347
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.652	0.348
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.652	0.348
V10-V19 Pedal cyclist injured in transport accident	0.651	0.349
Y85 Sequelae of transport accidents	0.649	0.351
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.648	0.352
C46 Kaposi's sarcoma	0.648	0.352
A41 Other septicaemia	0.648	0.352
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.646	0.354
J15.5 Pneumonia due to Escherichia coli	0.646	0.354
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.645	0.354
S42.0 Fracture of clavicle	0.645	0.355
S22.01 Fracture of thoracic vertebra (open)	0.645	0.355
J44.9 Chronic obstructive pulmonary disease, unspecified	0.644	0.356
C13 Malignant neoplasm of hypopharynx	0.644	0.356
C08 Malignant neoplasm of other and unspecified major salivary glands	0.644	0.356
C06 Malignant neoplasm of other and unspecified parts of mouth	0.644	0.356
C00 Malignant neoplasm of lip	0.644	0.356
T78.0 Anaphylactic shock due to adverse food reaction	0.644	0.356
T75 Effects of other external causes	0.644	0.356
C97 Malignant neoplasms of independent (primary) multiple sites	0.644	0.356
S46.2 Injury of muscle and tendon of other parts of biceps	0.643	0.357
J45.0 Predominantly allergic asthma	0.642	0.358
S20.4 Other superficial injuries of back wall of thorax	0.641	0.359
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.641	0.359
S82.60 Fracture of lateral malleolus (closed)	0.641	0.359
S27.2 Traumatic heamopneumothorax	0.641	0.359
W84 Unspecified threat to breathing	0.640	0.360
E74 Other disorders of carbohydrate metabolism	0.640	0.360
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.640	0.360
E84 Cystic fibrosis	0.640	0.360
E79 Disorders of purine and pyrimidine metabolism	0.640	0.360
E77 Disorders of glycoprotein metabolism	0.640	0.360
E76 Disorders of glycosaminoglycan metabolism	0.640	0.360
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.640	0.360
E72 Other disorders of amino-acid metabolism	0.640	0.360
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.640	0.360
E70 Disorders of aromatic amino-acid metabolism	0.640	0.360
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.640	0.360
C09.9 Tonsil, unspecified	0.639	0.361
C92.4 Acute promyelocytic leukaemia	0.638	0.362
W50-W64 Exposure to animate mechanical forces	0.638	0.362
C25.0 Head of pancreas	0.638	0.362
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.637	0.363
C12 Malignant neoplasm of pyriform sinus	0.637	0.363
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.636	0.364
C71.2 Temporal lobe	0.636	0.364
C11 Malignant neoplasm of nasopharynx	0.636	0.364
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.636	0.364
T90 Sequelae of injuries of head	0.635	0.364
E88.2 Lipomatosis, not elsewhere classified	0.635	0.365
S22.4 Multiple fractures of ribs	0.635	0.365
W06 Fall involving bed	0.635	0.365
J18.8 Other pneumonia, organism unspecified	0.634	0.365
J18.2 Hypostatic pneumonia, unspecified	0.634	0.365
F38 Other mood [affective] disorders	0.634	0.366
F00-F09 Organic, including symptomatic, mental disorders	0.633	0.367
S42.31 Fracture of shaft of humerus (open)	0.632	0.368
T91.8 Sequelae of other specified injuries of neck and trunk	0.632	0.368
J60-J70 Lung diseases due to external agents	0.631	0.369
J43 Emphysema	0.629	0.370
J86 Pyothorax	0.628	0.371
Y54.9 Mineral salts, not elsewhere classified	0.628	0.372
Y54.8 Agents affecting uric acid metabolism	0.628	0.372
Y54.7 Agents affecting calcification	0.628	0.372
Y54.6 Electrolytic, caloric and water-balance agents	0.628	0.372
Y54.2 Carbonic-anhydrase inhibitors	0.628	0.372
Y54.0 Mineralocorticoids	0.628	0.372
X62.9 Unspecified place	0.628	0.372
Y40.1 Cefalosporins and other -lactam antibiotics	0.627	0.373
S79 Other and unspecified injuries of hip and thigh	0.627	0.373
D80-D89 Certain disorders involving the immune mechanism	0.626	0.374
S82.70 Multiple fractures of lower leg (closed)	0.626	0.374
S06.0 Concussion	0.625	0.374
C45.2 Mesothelioma of pericardium	0.625	0.375
C45.1 Mesothelioma of peritoneum	0.625	0.375
C81 Hodgkin's disease	0.625	0.375
Y51 Drugs primarily affecting the autonomic nervous system	0.625	0.375
F30 Manic episode	0.624	0.376
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.622	0.378
C70 Malignant neoplasm of meninges	0.622	0.378
W78 Inhalation of gastric contents	0.621	0.378
Y48.5 Therapeutic gases	0.621	0.379
Y48.2 Other and unspecified general anaesthetics	0.621	0.379
Y48.1 Parenteral anaesthetics	0.621	0.379
Y48.0 Inhaled anaesthetics	0.621	0.379
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.621	0.379
S11 Open wound of neck	0.620	0.380
E83.9 Disorder of mineral metabolism, unspecified	0.620	0.380
E83.8 Other disorders of mineral metabolism	0.620	0.380
E83.2 Disorders of zinc metabolism	0.620	0.380
E83.0 Disorders of copper metabolism	0.620	0.380
F81 Specific developmental disorders of scholastic skills	0.619	0.380
A41.1 Septicaemia due to other specified staphylococcus	0.619	0.381
E88.3 Tumour lysis syndrome	0.619	0.381
T92 Sequelae of injuries of upper limb	0.619	0.381
B18.1 Chronic viral hepatitis B without delta-agent	0.619	0.381
T40.2 Other opioids	0.618	0.382
W17 Other fall from one level to another	0.618	0.382
J91 Pleural effusion in conditions classified elsewhere	0.618	0.382
T95 Sequelae of burns, corrosions and frostbite	0.618	0.382
C19 Malignant neoplasm of rectosigmoid junction	0.617	0.383
W49 Exposure to other and unspecified inanimate mechanical forces	0.617	0.383
T06 Other injuries involving multiple body regions, not elsewhere classified	0.617	0.383
T05 Traumatic amputations involving multiple body regions	0.617	0.383
T04 Crushing injuries involving multiple body regions	0.617	0.383
T03 Dislocations, sprains and strains involving multiple body regions	0.617	0.383
T07 Unspecified multiple injuries	0.617	0.383
C85.7 Other specified types of non-Hodgkin's lymphoma	0.617	0.383
Y53.4 Other laxatives	0.616	0.384
F31.0 Bipolar affective disorder, current episode hypomanic	0.615	0.385
J03 Acute tonsillitis	0.615	0.385
T21 Burn and corrosion of trunk	0.615	0.385
J98.0 Diseases of bronchus, not elsewhere classified	0.614	0.386
S40.0 Contusion of shoulder and upper arm	0.613	0.387
C26 Malignant neoplasm of other and ill-defined digestive organs	0.612	0.387
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.613	0.387
S22.2 Fracture of sternum	0.612	0.388
C92.9 Myeloid leukaemia, unspecified	0.612	0.388
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.612	0.388
C92.7 Other myeloid leukaemia	0.612	0.388
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.612	0.388
C92.5 Acute myelomonocytic leukaemia	0.612	0.388
C92.3 Myeloid sarcoma	0.612	0.388
C92.2 Subacute myeloid leukaemia	0.612	0.388
S22.10 Multiple fractures of thoracic spine (closed)	0.611	0.389
X84 Intentional self-harm by unspecified means	0.611	0.389
X83 Intentional self-harm by other specified means	0.611	0.389
X82 Intentional self-harm by crashing of motor vehicle	0.611	0.389
X81 Intentional self-harm by jumping or lying before moving object	0.611	0.389
X80 Intentional self-harm by jumping from a high place	0.611	0.389
X79 Intentional self-harm by blunt object	0.611	0.389
X77 Intentional self-harm by steam, hot vapours and hot objects	0.611	0.389
X76 Intentional self-harm by smoke, fire and flames	0.611	0.389
X75 Intentional self-harm by explosive material	0.611	0.389
X74 Intentional self-harm by other and unspecified firearm discharge	0.611	0.389
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge	0.611	0.389
X72 Intentional self-harm by handgun discharge	0.611	0.389
X71 Intentional self-harm by drowning and submersion	0.611	0.389
X70 Intentional self-harm by hanging, strangulation and suffocation	0.611	0.389
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.611	0.389
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours	0.611	0.389
X65 Intentional self-poisoning by and exposure to alcohol	0.611	0.389
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.611	0.389
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.611	0.389
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.611	0.389
C25.8 Overlapping lesion of pancreas	0.611	0.389
S21.2 Open wound of back wall of thorax	0.610	0.390
S00.7 Multiple superficial injuries of head	0.610	0.390
W94 Exposure to high and low air pressure and changes in air pressure	0.610	0.390
W10.8 Other specified place	0.610	0.390
S00.9 Superficial injury of head, part unspecified	0.610	0.390
F31.8 Other bipolar affective disorders	0.610	0.390
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.610	0.390
S06.9 Intracranial injury, unspecified	0.609	0.391

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations