TreeWAS – Variant ID: rs12358815

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N13.5 Kinking and stricture of ureter without hydronephrosis	0.053	0.947	0.000
Z45.8 Adjustment and management of other implanted devices	0.052	0.948	0.000
N13.8 Other obstructive and reflux uropathy	0.045	0.955	0.000
N13 Obstructive and reflux uropathy	0.044	0.956	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.035	0.965	0.000
N13.6 Pyonephrosis	0.035	0.965	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.032	0.968	0.000
N13.4 Hydroureter	0.031	0.969	0.000
N13.3 Other and unspecified hydronephrosis	0.031	0.969	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.028	0.972	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.026	0.974	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.022	0.978	0.000
Z45 Adjustment and management of implanted device	0.019	0.981	0.000
Z40-Z54 Persons encountering health services for specific procedures and health care	0.016	0.984	0.000
Z49 Care involving dialysis	0.015	0.985	0.000
Z46 Fitting and adjustment of other devices	0.015	0.985	0.000
Z49.0 Preparatory care for dialysis	0.015	0.985	0.000
Z45.3 Adjustment and management of implanted hearing device	0.015	0.985	0.000
Z52 Donors of organs and tissues	0.015	0.985	0.000
Z48 Other surgical follow-up care	0.014	0.986	0.000
Z45.9 Adjustment and management of unspecified implanted device	0.014	0.986	0.000
Z45.1 Adjustment and management of infusion pump	0.014	0.986	0.000
Z54 Convalescence	0.014	0.986	0.000
Z41 Procedures for purposes other than remedying health state	0.014	0.986	0.000
D68.2 Hereditary deficiency of other clotting factors	0.014	0.986	0.000
Z46.6 Fitting and adjustment of urinary device	0.013	0.987	0.000
Z52.4 Kidney donor	0.013	0.987	0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses	0.013	0.987	0.000
Z40 Prophylactic surgery	0.013	0.987	0.000
Z48.9 Surgical follow-up care, unspecified	0.013	0.987	0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances	0.013	0.987	0.000
Z49.2 Other dialysis	0.013	0.987	0.000
N10-N16 Renal tubulo-interstitial diseases	0.013	0.987	0.000
Z54.0 Convalescence following surgery	0.013	0.987	0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.013	0.987	0.000
Z46.7 Fitting and adjustment of orthopaedic device	0.012	0.988	0.000
Z52.0 Blood donor	0.012	0.988	0.000
Z46.3 Fitting and adjustment of dental prosthetic device	0.011	0.989	0.000
Z47 Other orthopaedic follow-up care	0.011	0.989	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.011	0.989	0.000
Z46.9 Fitting and adjustment of other unspecified device	0.011	0.989	0.000
Z46.4 Fitting and adjustment of orthodontic device	0.011	0.989	0.000
Z46.1 Fitting and adjustment of hearing aid	0.011	0.989	0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses	0.011	0.989	0.000
Z48.8 Other specified surgical follow-up care	0.011	0.989	0.000
Z52.3 Bone marrow donor	0.011	0.989	0.000
Z52.9 Donor of unspecified organ or tissue	0.011	0.989	0.000
Z52.8 Donor of other organs and tissues	0.011	0.989	0.000
Z52.7 Heart donor	0.011	0.989	0.000
Z52.6 Liver donor	0.011	0.989	0.000
Z52.5 Cornea donor	0.011	0.989	0.000
Z52.2 Bone donor	0.011	0.989	0.000
Z52.1 Skin donor	0.011	0.989	0.000
Z47.8 Other specified orthopaedic follow-up care	0.011	0.989	0.000
Z54.4 Convalescence following treatment of fracture	0.011	0.989	0.000
Z54.9 Convalescence following unspecified treatment	0.010	0.990	0.000
Z54.8 Convalescence following other treatment	0.010	0.990	0.000
Z54.7 Convalescence following combined treatment	0.010	0.990	0.000
Z54.3 Convalescence following psychotherapy	0.010	0.990	0.000
Z54.2 Convalescence following chemotherapy	0.010	0.990	0.000
Z54.1 Convalescence following radiotherapy	0.010	0.990	0.000
Z42 Follow-up care involving plastic surgery	0.010	0.990	0.000
Z41.9 Procedures for purposes other than remedying health state, unspecified	0.010	0.990	0.000
Z41.8 Other procedures for purposes other than remedying health state	0.010	0.990	0.000
Z41.3 Ear piercing	0.010	0.990	0.000
Z41.2 Routine and ritual circumcision	0.010	0.990	0.000
Z41.0 Hair transplant	0.010	0.990	0.000
Z43 Attention to artificial openings	0.010	0.990	0.000
I84.2 Internal haemorrhoids without complication	0.010	0.990	0.000
Z53.0 Procedure not carried out because of contraindication	0.000	0.990	0.010
Z40.8 Other prophylactic surgery	0.010	0.990	0.000
Z49.1 Extracorporeal dialysis	0.010	0.990	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.010	0.990	0.000
Z44 Fitting and adjustment of external prosthetic device	0.010	0.990	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.010	0.990	0.000
Z40.9 Prophylactic surgery, unspecified	0.010	0.990	0.000
D68 Other coagulation defects	0.010	0.990	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.010	0.990	0.000
N15 Other renal tubulo-interstitial diseases	0.010	0.990	0.000
Z43.8 Attention to other artificial openings	0.009	0.991	0.000
Z43.6 Attention to other artificial openings of urinary tract	0.009	0.991	0.000
Z48.0 Attention to surgical dressings and sutures	0.009	0.991	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.009	0.991	0.000
Z46.8 Fitting and adjustment of other specified devices	0.009	0.991	0.000
Z47.9 Orthopaedic follow-up care, unspecified	0.009	0.991	0.000
N10 Acute tubulo-interstitial nephritis	0.008	0.991	0.000
N11 Chronic tubulo-interstitial nephritis	0.008	0.992	0.000
D68.8 Other specified coagulation defects	0.008	0.992	0.000
Z42.1 Follow-up care involving plastic surgery of breast	0.008	0.992	0.000
Z42.8 Follow-up care involving plastic surgery of other body part	0.008	0.992	0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.008	0.992	0.000
D68.5 Primary Thrombophilia	0.008	0.992	0.000
D68.9 Coagulation defect, unspecified	0.008	0.992	0.000
Z42.9 Follow-up care involving plastic surgery, unspecified	0.007	0.992	0.000
Z43.9 Attention to unspecified artificial opening	0.007	0.992	0.000
Z43.7 Attention to artificial vagina	0.007	0.992	0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.008	0.992	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.007	0.992	0.000
Z44.9 Fitting and adjustment of unspecified external prosthetic device	0.007	0.993	0.000
Z44.8 Fitting and adjustment of other external prosthetic devices	0.007	0.993	0.000
Z44.2 Fitting and adjustment of artificial eye	0.007	0.993	0.000
Z44.1 Fitting and adjustment of artificial leg (complete)(partial)	0.007	0.993	0.000
Z44.0 Fitting and adjustment of artificial arm (complete)(partial)	0.007	0.993	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.007	0.993	0.000
N14.3 Nephropathy induced by heavy metals	0.007	0.993	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.007	0.993	0.000
N14.0 Analgesic nephropathy	0.007	0.993	0.000
D68.4 Acquired coagulation factor deficiency	0.007	0.993	0.000
D68.1 Hereditary factor XI deficiency	0.007	0.993	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.007	0.993	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.007	0.993	0.000
N15.1 Renal and perinephric abscess	0.007	0.993	0.000
N15.0 Balkan nephropathy	0.007	0.993	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.007	0.993	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.007	0.993	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.007	0.993	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.007	0.993	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.007	0.993	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.007	0.993	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.007	0.993	0.000
Z43.2 Attention to ileostomy	0.007	0.993	0.000
Z43.0 Attention to tracheostomy	0.007	0.993	0.000
D68.6 Other Thrombophilia	0.007	0.993	0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.007	0.993	0.000
Z43.1 Attention to gastrostomy	0.007	0.993	0.000
Z45.2 Adjustment and management of vascular access device	0.007	0.993	0.000
D68.0 Von Willebrand's disease	0.006	0.994	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.006	0.994	0.000
N11.1 Chronic obstructive pyelonephritis	0.006	0.994	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.006	0.994	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.006	0.994	0.000
Z43.5 Attention to cyctostomy	0.006	0.994	0.000
H54.0 Blindness, both eyes	0.006	0.994	0.000
Z43.4 Attention to other artificial openings of digestive tract	0.006	0.994	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.006	0.994	0.000
Z44.3 Fitting and adjustment of external breast prosthesis	0.005	0.994	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.000	0.994	0.005
D66 Hereditary factor VIII deficiency	0.005	0.995	0.000
Z43.3 Attention to colostomy	0.005	0.995	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.005	0.995	0.000
N87.0 Mild cervical dysplasia	0.000	0.995	0.005
H54 Blindness and low vision	0.005	0.995	0.000
N87 Dysplasia of cervix uteri	0.000	0.995	0.005
H54.4 Blindness, one eye	0.005	0.995	0.000
D67 Hereditary factor IX deficiency	0.004	0.996	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.004	0.996	0.000
H54.7 Unspecified visual loss	0.004	0.996	0.000
H54.5 Low vision, one eye	0.004	0.996	0.000
N87.2 Severe cervical dysplasia, not elsewhere classified	0.000	0.996	0.004
N87.1 Moderate cervical dysplasia	0.000	0.996	0.004
H54.6 Unqualified visual loss, one eye	0.004	0.996	0.000
Z45.0 Adjustment and management of cardiac pacemaker	0.001	0.996	0.003
M48.07 Spinal stenosis (Lumbosacral region)	0.000	0.996	0.004
H54.3 Unqualified visual loss, both eyes	0.004	0.996	0.000
H54.2 Low vision, both eyes	0.004	0.996	0.000
H54.1 Blindness, one eye, low vision, other eye	0.004	0.996	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.003	0.996	0.000
D69 Purpura and other haemorrhagic conditions	0.004	0.996	0.000
D69.5 Secondary thrombocytopenia	0.003	0.997	0.000
I87.8 Other specified disorders of veins	0.003	0.997	0.000
D69.4 Other primary thrombocytopenia	0.003	0.997	0.000
H54.9 Unspecified visual impairment (binocular)	0.003	0.997	0.000
D69.0 Allergic purpura	0.003	0.997	0.000
H20.9 Iridocyclitis, unspecified	0.003	0.997	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.003	0.997	0.000
R22.0 Localised swelling, mass and lump, head	0.000	0.997	0.003
D69.8 Other specified haemorrhagic conditions	0.003	0.997	0.000
D69.2 Other nonthrombocytopenic purpura	0.003	0.997	0.000
D69.1 Qualitative platelet defects	0.003	0.997	0.000
S42.00 Fracture of clavicle (closed)	0.000	0.997	0.003
I84.4 External haemorrhoids with other complications	0.003	0.997	0.000
M89.0 Algoneurodystrophy	0.003	0.997	0.000
N94.1 Dyspareunia	0.003	0.997	0.000
M89.04 Algoneurodystrophy (Hand)	0.003	0.997	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.003	0.997	0.000
G95.2 Cord compression, unspecified	0.003	0.997	0.000
I87 Other disorders of veins	0.003	0.997	0.000
Z36.8 Other antenatal screening	0.003	0.997	0.000
C85.1 B-cell lymphoma, unspecified	0.003	0.997	0.000
D69.9 Haemorrhagic condition, unspecified	0.002	0.997	0.000
M89.8 Other specified disorders of bone	0.003	0.997	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.002	0.997	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.002	0.997	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.002	0.998	0.000
G95.0 Syringomyelia and syringobulbia	0.002	0.998	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.002	0.998	0.000
M89.03 Algoneurodystrophy (Forearm)	0.002	0.998	0.000
G95.1 Vascular myelopathies	0.002	0.998	0.000
M50.3 Other cervical disk degeneration	0.002	0.998	0.000
Q61.3 Polycystic kidney, unspecified	0.002	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.998	0.002
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
I84.3 External thrombosed haemorrhoids	0.002	0.998	0.000
I84 Haemorrhoids	0.002	0.998	0.000
I84.8 Unspecified haemorrhoids with other complications	0.002	0.998	0.000
R74.8 Abnormal levels of other serum enzymes	0.002	0.998	0.000
M89 Other disorders of bone	0.002	0.998	0.000
M89.08 Algoneurodystrophy (Other)	0.002	0.998	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.002	0.998	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.002	0.998	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.002	0.998	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.002	0.998	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.002	0.998	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.002	0.998	0.000
M89.84 Other specified disorders of bone (Hand)	0.002	0.998	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.002	0.998	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.002	0.998	0.000
C25.9 Pancreas, unspecified	0.002	0.998	0.000
I87.9 Disorder of vein, unspecified	0.002	0.998	0.000
I87.0 Postphlebitic syndrome	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.002	0.998	0.000
O03.4 Incomplete, without complication	0.000	0.998	0.002
M89.89 Other specified disorders of bone (Site unspecified)	0.002	0.998	0.000
M89.88 Other specified disorders of bone (Other)	0.002	0.998	0.000
M89.83 Other specified disorders of bone (Forearm)	0.002	0.998	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.002	0.998	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.002	0.998	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.000	0.998	0.002
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.002	0.998	0.000
Z83.5 Family history of eye and ear disorders	0.002	0.998	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.002	0.998	0.000
D47.2 Monoclonal gammopathy	0.002	0.998	0.000
G95 Other diseases of spinal cord	0.002	0.998	0.000
H20 Iridocyclitis	0.002	0.998	0.000
M48.02 Spinal stenosis (Cervical region)	0.000	0.998	0.002
D05.1 Intraductal carcinoma in situ	0.000	0.998	0.002
D39.1 Ovary	0.002	0.998	0.000
I87.1 Compression of vein	0.002	0.998	0.000
D37.4 Colon	0.002	0.998	0.000
S43.0 Dislocation of shoulder joint	0.002	0.998	0.000
Z51.3 Blood transfusion without reported diagnosis	0.002	0.998	0.000
C64-C68 Malignant neoplasms of urinary tract	0.002	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.998	0.000
H20.1 Chronic iridocyclitis	0.002	0.998	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.002	0.998	0.000
C90.0 Multiple myeloma	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
H20.8 Other iridocyclitis	0.002	0.998	0.000
M89.6 Osteopathy after poliomyelitis	0.002	0.998	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.002	0.998	0.000
M89.2 Other disorders of bone development and growth	0.002	0.998	0.000
M89.1 Epiphyseal arrest	0.002	0.998	0.000
O70.0 First degree perineal laceration during delivery	0.002	0.998	0.000
Q61 Cystic kidney disease	0.002	0.998	0.000
L05.9 Pilonidal cyst without abscess	0.000	0.998	0.002
M89.5 Osteolysis	0.002	0.998	0.000
M89.3 Hypertrophy of bone	0.002	0.998	0.000
Q61.2 Polycystic kidney, adult type	0.002	0.998	0.000
I49.3 Ventricular premature depolarisation	0.002	0.998	0.000
I50.9 Heart failure, unspecified	0.000	0.998	0.002
I31.9 Disease of pericardium, unspecified	0.002	0.998	0.000
D47.4 Osteomyelofibrosis	0.002	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
D89.3 Immune reconstitution syndrome	0.002	0.998	0.000
D89.1 Cryoglobulinaemia	0.002	0.998	0.000
M50.2 Other cervical disk displacement	0.002	0.998	0.000
Z90.5 Acquired absence of kidney	0.002	0.998	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.002	0.998	0.000
C85.0 Lymphosarcoma	0.002	0.998	0.000
M48.0 Spinal stenosis	0.000	0.998	0.002
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.002	0.998	0.000
R20.8 Other and unspecified disturbances of skin sensation	0.000	0.998	0.002
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
D37.6 Liver, gallbladder and bile ducts	0.002	0.998	0.000
F45.8 Other somatoform disorders	0.000	0.998	0.002
H20.2 Lens-induced iridocyclitis	0.002	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
D44.3 Pituitary gland	0.002	0.998	0.000
Q61.5 Medullary cystic kidney	0.002	0.998	0.000
Z50.8 Care involving use of rehabilitation procedures	0.000	0.998	0.002
C90 Multiple myeloma and malignant plasma cell neoplasms	0.002	0.998	0.000
D55-D59 Haemolytic anaemias	0.002	0.998	0.000
C90.2 Plasmacytoma, extramedullary	0.002	0.998	0.000
D76.3 Other histiocytosis syndromes	0.002	0.998	0.000
D37.3 Appendix	0.002	0.998	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.002	0.998	0.000
D64.9 Anaemia, unspecified	0.002	0.998	0.000
D69.6 Thrombocytopenia, unspecified	0.002	0.998	0.000
I84.0 Internal thrombosed haemorrhoids	0.002	0.998	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.002	0.998	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.002	0.998	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.001	0.998	0.000
M89.18 Epiphyseal arrest (Other)	0.001	0.998	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.001	0.998	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.001	0.998	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.001	0.998	0.000
M89.14 Epiphyseal arrest (Hand)	0.001	0.998	0.000
M89.13 Epiphyseal arrest (Forearm)	0.001	0.998	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.001	0.998	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.001	0.998	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.001	0.998	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.001	0.998	0.000
M89.28 Other disorders of bone development and growth (Other)	0.001	0.998	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.001	0.998	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.001	0.998	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.001	0.998	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.001	0.998	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.001	0.998	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.001	0.998	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.001	0.998	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.001	0.998	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.001	0.998	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.001	0.998	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.001	0.998	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.001	0.998	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.001	0.998	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.001	0.998	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.001	0.998	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.001	0.998	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.001	0.998	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.001	0.998	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.001	0.998	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.001	0.998	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.001	0.998	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.001	0.998	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.001	0.998	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.001	0.998	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.001	0.998	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.001	0.998	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.001	0.998	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.001	0.998	0.000
H20.0 Acute and subacute iridocyclitis	0.002	0.998	0.000
Q61.9 Cystic kidney disease, unspecified	0.001	0.998	0.000
Q61.8 Other cystic kidney diseases	0.001	0.998	0.000
Q61.4 Renal dysplasia	0.001	0.998	0.000
Q61.1 Polycystic kidney, infantile type	0.001	0.998	0.000
Y54.5 Other diuretics	0.002	0.998	0.000
H55 Nystagmus and other irregular eye movements	0.002	0.998	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
M89.39 Hypertrophy of bone (Site unspecified)	0.001	0.998	0.000
M89.38 Hypertrophy of bone (Other)	0.001	0.998	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.001	0.998	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.001	0.998	0.000
M89.34 Hypertrophy of bone (Hand)	0.001	0.998	0.000
M89.33 Hypertrophy of bone (Forearm)	0.001	0.998	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.001	0.998	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.001	0.998	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.001	0.998	0.000
M89.59 Osteolysis (Site unspecified)	0.001	0.998	0.000
M89.58 Osteolysis (Other)	0.001	0.998	0.000
M89.57 Osteolysis (Ankle and foot)	0.001	0.998	0.000
M89.56 Osteolysis (Lower leg)	0.001	0.998	0.000
M89.54 Osteolysis (Hand)	0.001	0.998	0.000
M89.53 Osteolysis (Forearm)	0.001	0.998	0.000
M89.52 Osteolysis (Upper arm)	0.001	0.998	0.000
M89.51 Osteolysis (Shoulder region)	0.001	0.998	0.000
M89.50 Osteolysis (Multiple sites)	0.001	0.998	0.000
D37.1 Stomach	0.002	0.998	0.000
I89.0 Lymphoedema, not elsewhere classified	0.002	0.998	0.000
D72.1 Eosinophilia	0.002	0.998	0.000
M89.9 Disorder of bone, unspecified	0.002	0.998	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.002	0.998	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.001	0.998	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.001	0.998	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.001	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
C65 Malignant neoplasm of renal pelvis	0.001	0.998	0.000
D51 Vitamin B12 deficiency anaemia	0.002	0.998	0.000
D59 Acquired haemolytic anaemia	0.001	0.998	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.000	0.998	0.001
M48.03 Spinal stenosis (Cervicothoracic region)	0.000	0.998	0.001
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.000	0.998	0.001
Q61.0 Congenital single renal cyst	0.001	0.998	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.002	0.998	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.002	0.998	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.001	0.998	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.001	0.998	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.001	0.998	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.001	0.998	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.001	0.998	0.000
D84 Other immunodeficiencies	0.001	0.998	0.000
D83 Common variable immunodeficiency	0.001	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.001	0.998	0.000
D81 Combined immunodeficiencies	0.001	0.998	0.000
M48.09 Spinal stenosis (Site unspecified)	0.000	0.998	0.001
M89.98 Disorder of bone, unspecified (Other)	0.001	0.998	0.000
D58 Other hereditary haemolytic anaemias	0.001	0.998	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.001	0.998	0.000
D72 Other disorders of white blood cells	0.001	0.998	0.000
C90.3 Solitary plasmacytoma	0.001	0.998	0.000
C90.1 Plasma cell leukaemia	0.001	0.998	0.000
S42.0 Fracture of clavicle	0.000	0.998	0.001
C66 Malignant neoplasm of ureter	0.001	0.998	0.000
D57 Sickle-cell disorders	0.001	0.998	0.000
D56 Thalassaemia	0.001	0.998	0.000
D55 Anaemia due to enzyme disorders	0.001	0.998	0.000
E87.2 Acidosis	0.002	0.998	0.000
I49.0 Ventricular fibrillation and flutter	0.001	0.998	0.000
C68.9 Urinary organ, unspecified	0.001	0.999	0.000
C68.8 Overlapping lesion of urinary organs	0.001	0.999	0.000
C68.1 Paraurethral glands	0.001	0.999	0.000
C68.0 Urethra	0.001	0.999	0.000
C81.7 Other Hodgkin's disease	0.001	0.999	0.000
D39.0 Uterus	0.001	0.999	0.000
D44.7 Aortic body and other paraganglia	0.001	0.999	0.000
D39.9 Female genital organ, unspecified	0.001	0.999	0.000
D39.7 Other female genital organs	0.001	0.999	0.000
D39.2 Placenta	0.001	0.999	0.000
I49.4 Other and unspecified premature depolarisation	0.001	0.999	0.000
L05.0 Pilonidal cyst with abscess	0.000	0.999	0.001
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.001	0.999	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.999	0.001
D47.3 Essential (haemorrhagic) thrombocythaemia	0.001	0.999	0.000
K86.8 Other specified diseases of pancreas	0.000	0.999	0.001
T92.1 Sequelae of fracture of arm	0.001	0.999	0.000
D64 Other anaemias	0.001	0.999	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M89.99 Disorder of bone, unspecified (Site unspecified)	0.001	0.999	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.001	0.999	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.001	0.999	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.001	0.999	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.001	0.999	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.001	0.999	0.000
D72.8 Other specified disorders of white blood cells	0.001	0.999	0.000
O03 Spontaneous abortion	0.000	0.999	0.001
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.001	0.999	0.000
T92 Sequelae of injuries of upper limb	0.001	0.999	0.000
M13.96 Arthritis, unspecified (Lower leg)	0.000	0.999	0.001
M89.96 Disorder of bone, unspecified (Lower leg)	0.001	0.999	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
D37.9 Digestive organ, unspecified	0.001	0.999	0.000
D59.1 Other autoimmune haemolytic anaemias	0.001	0.999	0.000
O03.9 Complete or unspecified, without complication	0.000	0.999	0.001
S43.4 Sprain and strain of shoulder joint	0.001	0.999	0.000
S43.1 Dislocation of acromioclavicular joint	0.001	0.999	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.001	0.999	0.000
M48.04 Spinal stenosis (Thoracic region)	0.000	0.999	0.001
D47.1 Chronic myeloproliferative disease	0.001	0.999	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.001	0.999	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.001	0.999	0.000
D51.2 Transcobalamin II deficiency	0.001	0.999	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.001	0.999	0.000
D59.8 Other acquired haemolytic anaemias	0.001	0.999	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.001	0.999	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.001	0.999	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.001	0.999	0.000
D59.3 Haemolytic-uraemic syndrome	0.001	0.999	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.001	0.999	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.001	0.999	0.000
Q43.0 Meckel's diverticulum	0.001	0.999	0.000
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.001	0.999	0.000
Y43.3 Other antineoplastic drugs	0.001	0.999	0.000
D80 Immunodeficiency with predominantly antibody defects	0.001	0.999	0.000
D37.7 Other digestive organs	0.001	0.999	0.000
D44.9 Endocrine gland, unspecified	0.001	0.999	0.000
D44.8 Pluriglandular involvement	0.001	0.999	0.000
D44.6 Carotid body	0.001	0.999	0.000
D44.5 Pineal gland	0.001	0.999	0.000
D44.2 Parathyroid gland	0.001	0.999	0.000
D44.1 Adrenal gland	0.001	0.999	0.000
G61.0 Guillain-Barre syndrome	0.000	0.999	0.001
G95.8 Other specified diseases of spinal cord	0.001	0.999	0.001
J34.3 Hypertrophy of nasal turbinates	0.001	0.999	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.001	0.999	0.000
T92.0 Sequelae of open wound of upper limb	0.001	0.999	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.001	0.999	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.001	0.999	0.000
D44.4 Craniopharyngeal duct	0.001	0.999	0.000
D44.0 Thyroid gland	0.001	0.999	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.001	0.999	0.000
D55.8 Other anaemias due to enzyme disorders	0.001	0.999	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.001	0.999	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.001	0.999	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.001	0.999	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.001	0.999	0.000
D56.9 Thalassaemia, unspecified	0.001	0.999	0.000
D56.8 Other thalassaemias	0.001	0.999	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.001	0.999	0.000
D56.3 Thalassaemia trait	0.001	0.999	0.000
D56.2 Delta-beta thalassaemia	0.001	0.999	0.000
D56.1 Beta thalassaemia	0.001	0.999	0.000
D56.0 Alpha thalassaemia	0.001	0.999	0.000
D57.8 Other sickle-cell disorders	0.001	0.999	0.000
D57.3 Sickle-cell trait	0.001	0.999	0.000
D57.2 Double heterozygous sickling disorders	0.001	0.999	0.000
D57.1 Sickle-cell anaemia without crisis	0.001	0.999	0.000
D57.0 Sickle-cell anaemia with crisis	0.001	0.999	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.001	0.999	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.001	0.999	0.000
D58.2 Other haemoglobinopathies	0.001	0.999	0.000
D58.1 Hereditary elliptocytosis	0.001	0.999	0.000
D58.0 Hereditary spherocytosis	0.001	0.999	0.000
D72.9 Disorder of white blood cells, unspecified	0.001	0.999	0.000
D72.0 Genetic anomalies of leukocytes	0.001	0.999	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.001	0.999	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.001	0.999	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.001	0.999	0.000
D81.9 Combined immunodeficiency, unspecified	0.001	0.999	0.000
D81.8 Other combined immunodeficiencies	0.001	0.999	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.999	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.999	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.999	0.000
D81.4 Nezelof's syndrome	0.001	0.999	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.999	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.999	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.999	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.999	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations