TreeWAS – Variant ID: rs12365302

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M54.22 Cervicalgia (Cervical region)	0.020	0.980	0.000
N41.1 Chronic prostatitis	0.016	0.984	0.000
N41 Inflammatory diseases of prostate	0.013	0.987	0.000
Z98.2 Presence of cerebrospinal fluid drainage device	0.000	0.987	0.013
N41.0 Acute prostatitis	0.013	0.987	0.000
Z98.1 Arthrodesis status	0.000	0.987	0.013
N41.9 Inflammatory disease of prostate, unspecified	0.011	0.989	0.000
Z34.8 Supervision of other normal pregnancy	0.011	0.989	0.000
Z98 Other postsurgical states	0.000	0.989	0.010
M06.9 Rheumatoid arthritis, unspecified	0.000	0.990	0.010
M54.2 Cervicalgia	0.010	0.990	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.990	0.010
N41.8 Other inflammatory diseases of prostate	0.010	0.990	0.000
N41.3 Prostatocystitis	0.010	0.990	0.000
N41.2 Abscess of prostate	0.010	0.990	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.009	0.991	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.991	0.009
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.991	0.009
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.991	0.009
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.992	0.008
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.992	0.008
Z98.8 Other specified postsurgical states	0.000	0.992	0.008
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.992	0.008
M54.23 Cervicalgia (Cervicothoracic region)	0.008	0.992	0.000
M54.28 Cervicalgia-Sacral/sacrococ	0.007	0.992	0.000
M54.27 Cervicalgia-Lumbosacral	0.007	0.992	0.000
M54.26 Cervicalgia-Lumbar	0.007	0.992	0.000
M54.25 Cervicalgia-Thoracolumbar	0.007	0.992	0.000
M54.24 Cervicalgia-Thoracic	0.007	0.992	0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.007	0.992	0.000
M54.20 Cervicalgia-Mult site	0.007	0.992	0.000
M54.29 Cervicalgia-Site unspe	0.007	0.993	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.993	0.007
M06 Other rheumatoid arthritis	0.000	0.993	0.007
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.994	0.006
M06.0 Seronegative rheumatoid arthritis	0.000	0.994	0.006
C77.3 Axillary and upper limb lymph nodes	0.006	0.994	0.000
M06.4 Inflammatory polyarthropathy	0.000	0.994	0.006
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.994	0.005
C71.1 Frontal lobe	0.000	0.994	0.006
Z93.2 Ileostomy status	0.000	0.995	0.005
C71.9 Brain, unspecified	0.000	0.995	0.005
M06.8 Other specified rheumatoid arthritis	0.000	0.995	0.005
M06.2 Rheumatoid bursitis	0.000	0.995	0.005
M06.1 Adult-onset Still's disease	0.000	0.995	0.005
M54.46 Lumbago with sciatica (Lumbar region)	0.005	0.995	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.995	0.005
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.000	0.995	0.005
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.995	0.004
C71 Malignant neoplasm of brain	0.000	0.995	0.005
M54.4 Lumbago with sciatica	0.005	0.995	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.000	0.995	0.004
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.000	0.995	0.004
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.000	0.995	0.004
M06.04 Seronegative rheumatoid arthritis (Hand)	0.000	0.995	0.004
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.000	0.995	0.004
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.000	0.995	0.004
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.000	0.995	0.004
M06.3 Rheumatoid nodule	0.000	0.995	0.004
M54.49 Lumbago with sciatica (Site unspecified)	0.004	0.996	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.000	0.996	0.004
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.000	0.996	0.004
M06.46 Inflammatory polyarthropathy (Lower leg)	0.000	0.996	0.004
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.000	0.996	0.004
M06.44 Inflammatory polyarthropathy (Hand)	0.000	0.996	0.004
M06.43 Inflammatory polyarthropathy (Forearm)	0.000	0.996	0.004
M06.42 Inflammatory polyarthropathy (Upper arm)	0.000	0.996	0.004
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.000	0.996	0.004
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.000	0.996	0.004
C77.8 Lymph nodes of multiple regions	0.004	0.996	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.004	0.996	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.000	0.996	0.004
M06.18 Adult-onset Still's disease (Other)	0.000	0.996	0.004
M06.17 Adult-onset Still's disease (Ankle and foot)	0.000	0.996	0.004
M06.16 Adult-onset Still's disease (Lower leg)	0.000	0.996	0.004
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.000	0.996	0.004
M06.14 Adult-onset Still's disease (Hand)	0.000	0.996	0.004
M06.13 Adult-onset Still's disease (Forearm)	0.000	0.996	0.004
M06.12 Adult-onset Still's disease (Upper arm)	0.000	0.996	0.004
M06.11 Adult-onset Still's disease (Shoulder region)	0.000	0.996	0.004
M06.10 Adult-onset Still's disease (Multiple sites)	0.000	0.996	0.004
M06.29 Rheumatoid bursitis (Site unspecified)	0.000	0.996	0.004
M06.28 Rheumatoid bursitis (Other)	0.000	0.996	0.004
M06.27 Rheumatoid bursitis (Ankle and foot)	0.000	0.996	0.004
M06.26 Rheumatoid bursitis (Lower leg)	0.000	0.996	0.004
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.000	0.996	0.004
M06.24 Rheumatoid bursitis (Hand)	0.000	0.996	0.004
M06.23 Rheumatoid bursitis (Forearm)	0.000	0.996	0.004
M06.22 Rheumatoid bursitis (Upper arm)	0.000	0.996	0.004
M06.21 Rheumatoid bursitis (Shoulder region)	0.000	0.996	0.004
M06.20 Rheumatoid bursitis (Multiple sites)	0.000	0.996	0.004
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.000	0.996	0.004
M06.88 Other specified rheumatoid arthritis (Other)	0.000	0.996	0.004
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.000	0.996	0.004
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.000	0.996	0.004
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.000	0.996	0.004
M06.84 Other specified rheumatoid arthritis (Hand)	0.000	0.996	0.004
M06.83 Other specified rheumatoid arthritis (Forearm)	0.000	0.996	0.004
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.000	0.996	0.004
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.000	0.996	0.004
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.000	0.996	0.004
C71.0 Cerebrum, except lobes and ventricles	0.000	0.996	0.004
F03 Unspecified dementia	0.004	0.996	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.996	0.004
C71.8 Overlapping lesion of brain	0.000	0.996	0.004
C71.2 Temporal lobe	0.000	0.996	0.004
M06.34 Rheumatoid nodule (Hand)	0.000	0.996	0.003
K86.2 Cyst of pancreas	0.004	0.996	0.000
Z98.0 Intestinal bypass and anastomosis status	0.000	0.996	0.004
C71.7 Brain stem	0.000	0.996	0.003
C71.6 Cerebellum	0.000	0.996	0.003
C71.5 Cerebral ventricle	0.000	0.996	0.003
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.003	0.996	0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.003	0.996	0.000
M54.44 Lumbago with sciatica-Thoracic	0.003	0.996	0.000
M54.43 Lumbago with sciatica-Cervicothoracic	0.003	0.996	0.000
M54.42 Lumbago with sciatica-Cervical	0.003	0.996	0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.003	0.996	0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.003	0.996	0.000
Z93.3 Colostomy status	0.000	0.996	0.004
M06.39 Rheumatoid nodule (Site unspecified)	0.000	0.996	0.003
M06.38 Rheumatoid nodule (Other)	0.000	0.996	0.003
M06.37 Rheumatoid nodule (Ankle and foot)	0.000	0.996	0.003
M06.36 Rheumatoid nodule (Lower leg)	0.000	0.996	0.003
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.000	0.996	0.003
M06.33 Rheumatoid nodule (Forearm)	0.000	0.996	0.003
M06.31 Rheumatoid nodule (Shoulder region)	0.000	0.996	0.003
M06.30 Rheumatoid nodule (Multiple sites)	0.000	0.996	0.003
F01.9 Vascular dementia, unspecified	0.003	0.997	0.000
U80.0 Penicillin resistant agent	0.003	0.997	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.003	0.997	0.000
C77.2 Intra-abdominal lymph nodes	0.003	0.997	0.000
C71.4 Occipital lobe	0.000	0.997	0.003
F01 Vascular dementia	0.003	0.997	0.000
S42.00 Fracture of clavicle (closed)	0.003	0.997	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.003	0.997	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
Z93 Artificial opening status	0.000	0.997	0.003
C77.0 Lymph nodes of head, face and neck	0.003	0.997	0.000
D50.8 Other iron deficiency anaemias	0.003	0.997	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.000	0.997	0.003
C71.3 Parietal lobe	0.000	0.997	0.003
R94.3 Abnormal results of cardiovascular function studies	0.000	0.997	0.003
Z43.2 Attention to ileostomy	0.000	0.997	0.003
F00 Dementia in Alzheimer's disease	0.003	0.997	0.000
L90.0 Lichen sclerosus et atrophicus	0.003	0.997	0.000
F02 Dementia in other diseases classified elsewhere	0.003	0.997	0.000
F05.1 Delirium superimposed on dementia	0.003	0.997	0.000
F45.8 Other somatoform disorders	0.000	0.997	0.003
Z34 Supervision of normal pregnancy	0.003	0.997	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.003	0.997	0.000
M54 Dorsalgia	0.003	0.997	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.003	0.997	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.997	0.003
M79.60 Pain in limb (Multiple sites)	0.000	0.997	0.003
C18.2 Ascending colon	0.003	0.997	0.000
F01.8 Other vascular dementia	0.002	0.997	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.002	0.997	0.000
F01.2 Subcortical vascular dementia	0.002	0.997	0.000
F01.1 Multi-infarct dementia	0.002	0.997	0.000
F01.0 Vascular dementia of acute onset	0.002	0.997	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.003	0.997	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.003	0.997	0.000
Z93.1 Gastrostomy status	0.000	0.997	0.003
F05 Delirium, not induced by alcohol and other psychoactive substances	0.003	0.997	0.000
F09 Unspecified organic or symptomatic mental disorder	0.002	0.997	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.002	0.997	0.000
C18.1 Appendix	0.003	0.997	0.000
Z93.0 Tracheostomy status	0.000	0.997	0.002
Z93.9 Artificial opening status, unspecified	0.000	0.998	0.002
S72.20 Subtrochanteric fracture (closed)	0.000	0.998	0.002
F02.0 Dementia in Pick's disease	0.002	0.998	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.002	0.998	0.000
F07.2 Postconcussional syndrome	0.002	0.998	0.000
C77.4 Inguinal and lower limb lymph nodes	0.002	0.998	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.002	0.998	0.000
F02.2 Dementia in Huntington's disease	0.002	0.998	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.002	0.998	0.000
M54.8 Other dorsalgia	0.002	0.998	0.000
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
F05.8 Other delirium	0.002	0.998	0.000
C18.3 Hepatic flexure	0.002	0.998	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.002	0.998	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.002	0.998	0.000
C77.9 Lymph node, unspecified	0.002	0.998	0.000
M54.0 Panniculitis affecting regions of neck and back	0.002	0.998	0.000
F02.3 Dementia in Parkinson's disease	0.002	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.998	0.002
C92.1 Chronic myeloid leukaemia	0.002	0.998	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.002	0.998	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.002	0.998	0.000
F07.1 Postencephalitic syndrome	0.002	0.998	0.000
F07.0 Organic personality disorder	0.002	0.998	0.000
Z93.8 Other artificial opening status	0.000	0.998	0.002
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
M54.1 Radiculopathy	0.002	0.998	0.000
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
Z93.4 Other artificial openings of gastro-intestinal tract status	0.000	0.998	0.002
C53.9 Cervix uteri, unspecified	0.002	0.998	0.000
S92.3 Fracture of metatarsal bone	0.002	0.998	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M67.8 Other specified disorders of synovium and tendon	0.000	0.998	0.002
S22.40 Multiple fractures of ribs (closed)	0.000	0.998	0.002
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
C18 Malignant neoplasm of colon	0.002	0.998	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.002	0.998	0.000
C77.5 Intrapelvic lymph nodes	0.002	0.998	0.000
K61.0 Anal abscess	0.000	0.998	0.002
S92.0 Fracture of calcaneus	0.002	0.998	0.000
M54.6 Pain in thoracic spine	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.002	0.998	0.000
K02.9 Dental caries, unspecified	0.002	0.998	0.000
S91.3 Open wound of other parts of foot	0.002	0.998	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M54.89 Other dorsalgia (Site unspecified)	0.002	0.998	0.000
S72.40 Fracture of lower end of femur (closed)	0.000	0.998	0.002
N02.8 Other	0.002	0.998	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
C18.6 Descending colon	0.002	0.998	0.000
R41.0 Disorientation, unspecified	0.000	0.998	0.002
F05.0 Delirium not superimposed on dementia, so described	0.002	0.998	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S72.2 Subtrochanteric fracture	0.000	0.998	0.002
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M54.87 Other dorsalgia (Lumbosacral region)	0.002	0.998	0.000
M54.86 Other dorsalgia (Lumbar region)	0.002	0.998	0.000
M54.85 Other dorsalgia (Thoracolumbar region)	0.002	0.998	0.000
M54.84 Other dorsalgia (Thoracic region)	0.002	0.998	0.000
M54.83 Other dorsalgia (Cervicothoracic region)	0.002	0.998	0.000
M54.82 Other dorsalgia (Cervical region)	0.002	0.998	0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.002	0.998	0.000
M54.80 Other dorsalgia (Multiple sites in spine)	0.002	0.998	0.000
L95.9 Vasculitis limited to skin, unspecified	0.000	0.998	0.002
S42.0 Fracture of clavicle	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.002	0.998	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.000	0.998	0.002
S92.5 Fracture of other toe	0.002	0.998	0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)	0.002	0.998	0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)	0.002	0.998	0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)	0.002	0.998	0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)	0.002	0.998	0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)	0.002	0.998	0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)	0.002	0.998	0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)	0.002	0.998	0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)	0.002	0.998	0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)	0.002	0.998	0.000
X62.9 Unspecified place	0.002	0.998	0.000
D07.5 Prostate	0.002	0.998	0.000
S72.1 Pertrochanteric fracture	0.000	0.998	0.002
M54.15 Radiculopathy (Thoracolumbar region)	0.002	0.998	0.000
M54.14 Radiculopathy (Thoracic region)	0.002	0.998	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.002	0.998	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.002	0.998	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.002	0.998	0.000
M54.12 Radiculopathy (Cervical region)	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.002	0.998	0.000
M54.16 Radiculopathy (Lumbar region)	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.002	0.998	0.000
S91 Open wound of ankle and foot	0.002	0.998	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.002	0.998	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.002	0.998	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.002	0.998	0.000
F06.5 Organic dissociative disorder	0.002	0.998	0.000
F06.4 Organic anxiety disorder	0.002	0.998	0.000
F06.3 Organic mood [affective] disorders	0.002	0.998	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.002	0.998	0.000
F06.1 Organic catatonic disorder	0.002	0.998	0.000
F06.0 Organic hallucinosis	0.002	0.998	0.000
L23.1 Allergic contact dermatitis due to adhesives	0.002	0.998	0.000
N35.9 Urethral stricture, unspecified	0.000	0.998	0.002
S91.0 Open wound of ankle	0.002	0.998	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.998	0.002
M54.17 Radiculopathy (Lumbosacral region)	0.002	0.998	0.000
S92.01 Fracture of calcaneus (open)	0.002	0.998	0.000
C18.7 Sigmoid colon	0.002	0.998	0.000
S72.4 Fracture of lower end of femur	0.000	0.998	0.002
Z01.6 Radiological examination, not elsewhere classified	0.000	0.998	0.002
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.002	0.998	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.002	0.998	0.000
M54.69 Pain in thoracic spine-Site unspe	0.002	0.998	0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.002	0.998	0.000
M54.67 Pain in thoracic spine-Lumbosacral	0.002	0.998	0.000
M54.66 Pain in thoracic spine-Lumbar	0.002	0.998	0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.002	0.998	0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.002	0.998	0.000
M54.62 Pain in thoracic spine-Cervical	0.002	0.998	0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.002	0.998	0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
D25.1 Intramural leiomyoma of uterus	0.002	0.998	0.000
M16.3 Other dysplastic coxarthrosis	0.002	0.998	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S92.1 Fracture of talus	0.002	0.998	0.000
C18.8 Overlapping lesion of colon	0.002	0.998	0.000
S72.21 Subtrochanteric fracture (open)	0.000	0.998	0.001
L23.5 Allergic contact dermatitis due to other chemical products	0.002	0.998	0.000
S22.4 Multiple fractures of ribs	0.000	0.998	0.002
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.998	0.002
S42.01 Fracture of clavicle (open)	0.001	0.998	0.000
Q18.1 Preauricular sinus and cyst	0.002	0.998	0.000
S93.4 Sprain and strain of ankle	0.001	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.001	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.001	0.998	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.001	0.998	0.000
Z93.5 Cystostomy status	0.000	0.998	0.001
C53.0 Endocervix	0.002	0.998	0.000
N95.2 Postmenopausal atrophic vaginitis	0.000	0.998	0.002
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
C53 Malignant neoplasm of cervix uteri	0.002	0.998	0.000
M67 Other disorders of synovium and tendon	0.000	0.998	0.002
S52.00 Fracture of upper end of ulna (closed)	0.002	0.998	0.000
Z34.0 Supervision of normal first pregnancy	0.001	0.998	0.000
U80 Agent resistant to penicillin and related antibiotics	0.002	0.998	0.000
S72.11 Pertrochanteric fracture (open)	0.000	0.998	0.001
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.998	0.002
S92.4 Fracture of great toe	0.001	0.998	0.000
S92.50 Fracture of other toe (closed)	0.001	0.998	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.001	0.998	0.000
S91.2 Open wound of toe(s) with damage to nail	0.001	0.998	0.000
Z93.6 Other artificial openings of urinary tract status	0.000	0.998	0.002
S72 Fracture of femur	0.000	0.998	0.002
S92.70 Multiple fractures of foot (closed)	0.001	0.998	0.000
H61.1 Non-infective disorders of pinna	0.002	0.998	0.000
Y83.8 Other surgical procedures	0.002	0.998	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.000	0.998	0.001
M54.64 Pain in thoracic spine (Thoracic region)	0.001	0.998	0.000
S72.41 Fracture of lower end of femur (open)	0.000	0.998	0.001
S92.71 Multiple fractures of foot (open)	0.001	0.998	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.001	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.001	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.001	0.998	0.000
C67.9 Bladder, unspecified	0.000	0.998	0.002
G61.0 Guillain-Barre syndrome	0.002	0.998	0.000
S72.3 Fracture of shaft of femur	0.000	0.998	0.001
S97 Crushing injury of ankle and foot	0.001	0.998	0.000
M54.19 Radiculopathy (Site unspecified)	0.001	0.998	0.000
S92.11 Fracture of talus (open)	0.001	0.998	0.000
C18.0 Caecum	0.002	0.998	0.000
X67.0 Home	0.001	0.998	0.000
S72.30 Fracture of shaft of femur (closed)	0.000	0.998	0.001
M67.1 Other contracture of tendon (sheath)	0.000	0.998	0.001
X49.9 Unspecified place	0.000	0.998	0.001
C55 Malignant neoplasm of uterus, part unspecified	0.001	0.998	0.000
C70 Malignant neoplasm of meninges	0.000	0.998	0.001
Q18 Other congenital malformations of face and neck	0.001	0.998	0.000
S22.41 Multiple fractures of ribs (open)	0.000	0.999	0.001
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.999	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.001	0.999	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.001	0.999	0.000
C69 Malignant neoplasm of eye and adnexa	0.000	0.999	0.001
S92.10 Fracture of talus (closed)	0.001	0.999	0.000
S93.40 Sprain of unspecified ligament of ankle	0.001	0.999	0.000
S22.1 Multiple fractures of thoracic spine	0.000	0.999	0.001
Y84.6 Urinary catheterisation	0.001	0.999	0.000
C53.8 Overlapping lesion of cervix uteri	0.001	0.999	0.000
C53.1 Exocervix	0.001	0.999	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.000	0.999	0.001
M67.3 Transient synovitis	0.000	0.999	0.001
M67.0 Short Achilles tendon (acquired)	0.000	0.999	0.001
S22.0 Fracture of thoracic vertebra	0.000	0.999	0.001
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.001	0.999	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.999	0.001
M94.26 Chondromalacia (Lower leg)	0.001	0.999	0.000
M67.4 Ganglion	0.000	0.999	0.001
Y60.4 During endoscopic examination	0.001	0.999	0.000
S98 Traumatic amputation of ankle and foot	0.001	0.999	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.001	0.999	0.000
S95 Injury of blood vessels at ankle and foot level	0.001	0.999	0.000
S94 Injury of nerves at ankle and foot level	0.001	0.999	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.001	0.999	0.000
C18.4 Transverse colon	0.001	0.999	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.001	0.999	0.000
C18.5 Splenic flexure	0.001	0.999	0.000
C69.9 Eye, unspecified	0.000	0.999	0.001
C72.9 Central nervous system, unspecified	0.000	0.999	0.001
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.000	0.999	0.001
C72.5 Other and unspecified cranial nerves	0.000	0.999	0.001
C72.4 Acoustic nerve	0.000	0.999	0.001
C72.3 Optic nerve	0.000	0.999	0.001
C72.2 Olfactory nerve	0.000	0.999	0.001
C72.1 Cauda equina	0.000	0.999	0.001
C72.0 Spinal cord	0.000	0.999	0.001
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.001	0.999	0.000
S72.7 Multiple fractures of femur	0.000	0.999	0.001
S92.20 Fracture of other tarsal bone(s) (closed)	0.001	0.999	0.000
S72.8 Fractures of other parts of femur	0.000	0.999	0.001
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.999	0.001
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.001	0.999	0.000
S72.31 Fracture of shaft of femur (open)	0.000	0.999	0.001
S82.30 Fracture of lower end of tibia (closed)	0.001	0.999	0.000
S97.1 Crushing injury of toe(s)	0.001	0.999	0.000
S97.0 Crushing injury of ankle	0.001	0.999	0.000
S92.41 Fracture of great toe (open)	0.001	0.999	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
S22.20 Fracture of sternum (closed)	0.000	0.999	0.001
C69.8 Overlapping lesion of eye and adnexa	0.000	0.999	0.001
C69.6 Orbit	0.000	0.999	0.001
C69.5 Lachrymal gland and duct	0.000	0.999	0.001
C69.4 Ciliary body	0.000	0.999	0.001
C69.2 Retina	0.000	0.999	0.001
C69.1 Cornea	0.000	0.999	0.001
C69.0 Conjunctiva	0.000	0.999	0.001
C70.9 Meninges, unspecified	0.000	0.999	0.001
C70.1 Spinal meninges	0.000	0.999	0.001
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.000	0.999	0.001
D89.1 Cryoglobulinaemia	0.001	0.999	0.000
I82.2 Embolism and thrombosis of vena cava	0.001	0.999	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.001	0.999	0.000
Q18.8 Other specified congenital malformations of face and neck	0.001	0.999	0.000
Q18.7 Microcheilia	0.001	0.999	0.000
Q18.6 Macrocheilia	0.001	0.999	0.000
Q18.5 Microstomia	0.001	0.999	0.000
Q18.4 Macrostomia	0.001	0.999	0.000
Q18.3 Webbing of neck	0.001	0.999	0.000
Q18.2 Other branchial cleft malformations	0.001	0.999	0.000
S72.9 Fracture of femur, part unspecified	0.000	0.999	0.001
M65.34 Trigger finger-Hand	0.001	0.999	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.999	0.001
S22.2 Fracture of sternum	0.000	0.999	0.001
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.001	0.999	0.000
M67.49 Ganglion, multiple sites	0.000	0.999	0.001
M67.47 Ganglion, ankle and foot	0.000	0.999	0.001
M67.45 Ganglion, hip	0.000	0.999	0.001
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.000	0.999	0.001
S22.01 Fracture of thoracic vertebra (open)	0.000	0.999	0.001
C54.1 Endometrium	0.001	0.999	0.000
K05.1 Chronic gingivitis	0.001	0.999	0.000
R23.4 Changes in skin texture	0.000	0.999	0.001
X62.0 Home	0.001	0.999	0.000
X62.8 Other specified place	0.001	0.999	0.000
X62.7 Farm	0.001	0.999	0.000
X62.6 Industrial and construction area	0.001	0.999	0.000
X62.5 Trade and service area	0.001	0.999	0.000
X62.4 Street and highway	0.001	0.999	0.000
X62.3 Sports and athletics area	0.001	0.999	0.000
X62.2 School, other institution and public administrative area	0.001	0.999	0.000
X62.1 Residential institution	0.001	0.999	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.000	0.999	0.001
L23 Allergic contact dermatitis	0.001	0.999	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.999	0.001
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.999	0.001
S92.40 Fracture of great toe (closed)	0.001	0.999	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.001	0.999	0.000
F06.7 Mild cognitive disorder	0.001	0.999	0.000
R40.2 Coma, unspecified	0.000	0.999	0.001
S91.1 Open wound of toe(s) without damage to nail	0.001	0.999	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.001	0.999	0.000
S94.8 Injury of other nerves at ankle and foot level	0.001	0.999	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.001	0.999	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.001	0.999	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.001	0.999	0.000
S94.1 Injury of medial plantar nerve	0.001	0.999	0.000
S94.0 Injury of lateral plantar nerve	0.001	0.999	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.001	0.999	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.001	0.999	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.001	0.999	0.000
S95.2 Injury of dorsal vein of foot	0.001	0.999	0.000
S95.1 Injury of plantar artery of foot	0.001	0.999	0.000
S95.0 Injury of dorsal artery of foot	0.001	0.999	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.001	0.999	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.001	0.999	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.001	0.999	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.001	0.999	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.001	0.999	0.000
S98.3 Traumatic amputation of other parts of foot	0.001	0.999	0.000
S98.2 Traumatic amputation of two or more toes	0.001	0.999	0.000
S98.1 Traumatic amputation of one toe	0.001	0.999	0.000
S98.0 Traumatic amputation of foot at ankle level	0.001	0.999	0.000
Y60.5 During heart catheterisation	0.001	0.999	0.000
M67.43 Ganglion, wrist	0.000	0.999	0.001
S72.71 Multiple fractures of femur (open)	0.000	0.999	0.001
S72.70 Multiple fractures of femur (closed)	0.000	0.999	0.001
C18.9 Colon, unspecified	0.001	0.999	0.000
C70.0 Cerebral meninges	0.000	0.999	0.001
G70.0 Myasthenia gravis	0.001	0.999	0.000
G91.9 Hydrocephalus, unspecified	0.000	0.999	0.001
S40.8 Other superficial injuries of shoulder and upper arm	0.001	0.999	0.000
S93.1 Dislocation of toe(s)	0.001	0.999	0.000
U80.1 Methicillin resistant agent	0.001	0.999	0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.001	0.999	0.000
S72.81 Fractures of other parts of femur (open)	0.000	0.999	0.001
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.001	0.999	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.001	0.999	0.000
N02 Recurrent and persistent haematuria	0.001	0.999	0.000
S99 Other and unspecified injuries of ankle and foot	0.001	0.999	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
D80 Immunodeficiency with predominantly antibody defects	0.001	0.999	0.000
M25.46 Effusion of joint (Lower leg)	0.000	0.999	0.001
S22.21 Fracture of sternum (open)	0.000	0.999	0.001
S72.80 Fractures of other parts of femur (closed)	0.000	0.999	0.001
S72.91 Fracture of femur, part unspecified (open)	0.000	0.999	0.001
D89.2 Hypergammaglobulinaemia, unspecified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations