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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12380424
log Bayes Factor = 0.099035
Chromosome 9   position 131,403,221  (GRCh37) Explore rs12380424 on Ensembl!
Variant rs12380424 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.0 Pure hypercholesterolaemia
0.000 0.889 0.111
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.895 0.105
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.896 0.104
E70-E90 Metabolic disorders
0.000 0.896 0.104
E10-E14 Diabetes mellitus
0.000 0.900 0.100
E00-E07 Disorders of thyroid gland
0.000 0.904 0.096
E10 Insulin-dependent diabetes mellitus
0.000 0.907 0.093
E50-E64 Other nutritional deficiencies
0.000 0.907 0.092
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.909 0.091
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.909 0.091
E03 Other hypothyroidism
0.000 0.911 0.089
E10.9 Without complications
0.000 0.912 0.088
E78.5 Hyperlipidaemia, unspecified
0.000 0.912 0.088
E14 Unspecified diabetes mellitus
0.000 0.913 0.087
E53 Deficiency of other B group vitamins
0.000 0.915 0.085
E03.9 Hypothyroidism, unspecified
0.000 0.916 0.084
E87.5 Hyperkalaemia
0.000 0.916 0.084
E16 Other disorders of pancreatic internal secretion
0.000 0.917 0.082
E53.8 Deficiency of other specified B group vitamins
0.000 0.920 0.080
E87.6 Hypokalaemia
0.000 0.922 0.078
E07 Other disorders of thyroid
0.000 0.923 0.077
E16.2 Hypoglycaemia, unspecified
0.000 0.924 0.076
E78.6 Lipoprotein deficiency
0.000 0.924 0.076
E78.3 Hyperchylomicronaemia
0.000 0.924 0.076
E78.1 Pure hyperglyceridaemia
0.000 0.924 0.076
E40-E46 Malnutrition
0.000 0.925 0.075
E85 Amyloidosis
0.000 0.925 0.075
E84 Cystic fibrosis
0.000 0.925 0.075
E79 Disorders of purine and pyrimidine metabolism
0.000 0.925 0.075
E77 Disorders of glycoprotein metabolism
0.000 0.925 0.075
E76 Disorders of glycosaminoglycan metabolism
0.000 0.925 0.075
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.925 0.075
E74 Other disorders of carbohydrate metabolism
0.000 0.925 0.075
E73 Lactose intolerance
0.000 0.925 0.075
E72 Other disorders of amino-acid metabolism
0.000 0.925 0.075
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.925 0.075
E70 Disorders of aromatic amino-acid metabolism
0.000 0.925 0.075
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.925 0.075
E14.9 Without complications
0.000 0.925 0.075
E11 Non-insulin-dependent diabetes mellitus
0.000 0.926 0.074
E10.3 With ophthalmic complications
0.000 0.926 0.073
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.927 0.073
E88 Other metabolic disorders
0.000 0.928 0.072
E12 Malnutrition-related diabetes mellitus
0.000 0.928 0.072
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.929 0.071
E86 Volume depletion
0.000 0.930 0.070
E78.2 Mixed hyperlipidaemia
0.000 0.930 0.069
E13 Other specified diabetes mellitus
0.000 0.931 0.069
E78.8 Other disorders of lipoprotein metabolism
0.000 0.931 0.069
E61 Deficiency of other nutrient elements
0.000 0.931 0.069
E06 Thyroiditis
0.000 0.931 0.069
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.931 0.069
E00 Congenital iodine-deficiency syndrome
0.000 0.931 0.069
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.931 0.069
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.932 0.068
E65-E68 Obesity and other hyperalimentation
0.000 0.932 0.068
E14.3 With ophthalmic complications
0.000 0.932 0.068
E78.4 Other hyperlipidaemia
0.000 0.932 0.067
E10.8 With unspecified complications
0.000 0.933 0.067
E10.7 With multiple complications
0.000 0.933 0.067
E10.6 With other specified complications
0.000 0.933 0.067
E10.5 With peripheral circulatory complications
0.000 0.933 0.067
E10.4 With neurological complications
0.000 0.933 0.067
E10.2 With renal complications
0.000 0.933 0.067
E10.0 With coma
0.000 0.933 0.067
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.933 0.066
E63 Other nutritional deficiencies
0.000 0.933 0.066
E56 Other vitamin deficiencies
0.000 0.933 0.066
E51 Thiamine deficiency
0.000 0.933 0.066
E50 Vitamin A deficiency
0.000 0.933 0.066
E60 Dietary zinc deficiency
0.000 0.933 0.066
E59 Dietary selenium deficiency
0.000 0.933 0.066
E58 Dietary calcium deficiency
0.000 0.933 0.066
E54 Ascorbic acid deficiency
0.000 0.933 0.066
E52 Niacin deficiency [pellagra]
0.000 0.933 0.066
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.934 0.066
E15 Nondiabetic hypoglycaemic coma
0.000 0.934 0.066
E87.4 Mixed disorder of acid-base balance
0.000 0.935 0.065
E87.3 Alkalosis
0.000 0.935 0.065
E83 Disorders of mineral metabolism
0.000 0.936 0.064
E03.8 Other specified hypothyroidism
0.000 0.936 0.064
E03.5 Myxoedema coma
0.000 0.936 0.064
E03.4 Atrophy of thyroid (acquired)
0.000 0.936 0.064
E03.3 Postinfectious hypothyroidism
0.000 0.936 0.064
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.936 0.064
E03.1 Congenital hypothyroidism without goitre
0.000 0.936 0.064
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.936 0.064
E07.9 Disorder of thyroid, unspecified
0.000 0.936 0.063
E87.2 Acidosis
0.000 0.937 0.063
E14.8 With unspecified complications
0.000 0.938 0.062
E14.7 With multiple complications
0.000 0.938 0.062
E14.6 With other specified complications
0.000 0.938 0.062
E14.5 With peripheral circulatory complications
0.000 0.938 0.062
E14.4 With neurological complications
0.000 0.938 0.062
E14.2 Withrenal complications
0.000 0.938 0.062
E14.1 With ketoacidosis
0.000 0.938 0.062
E14.0 With coma
0.000 0.938 0.062
E55 Vitamin D deficiency
0.000 0.938 0.062
E87.7 Fluid overload
0.000 0.938 0.062
E53.9 Vitamin B deficiency, unspecified
0.000 0.939 0.061
E53.1 Pyridoxine deficiency
0.000 0.939 0.061
E53.0 Riboflavin deficiency
0.000 0.939 0.061
E11.3 With ophthalmic complications
0.000 0.940 0.060
M17.9 Gonarthrosis, unspecified
0.000 0.940 0.060
E87.0 Hyperosmolality and hypernatraemia
0.000 0.940 0.060
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.941 0.059
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.941 0.059
E16.4 Abnormal secretion of gastrin
0.000 0.941 0.059
E16.3 Increased secretion of glucagon
0.000 0.941 0.059
E16.1 Other hypoglycaemia
0.000 0.941 0.059
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.941 0.059
E04 Other non-toxic goitre
0.000 0.941 0.059
E11.5 With peripheral circulatory complications
0.000 0.941 0.059
E10.1 With ketoacidosis
0.000 0.942 0.058
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.942 0.058
E07.8 Other specified disorders of thyroid
0.000 0.945 0.055
E07.1 Dyshormogenetic goitre
0.000 0.945 0.055
E07.0 Hypersecretion of calcitonin
0.000 0.945 0.055
E05.9 Thyrotoxicosis, unspecified
0.000 0.945 0.055
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.945 0.054
E20-E35 Disorders of other endocrine glands
0.000 0.946 0.054
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.946 0.054
E46 Unspecified protein-energy malnutrition
0.000 0.946 0.054
E45 Retarded development following protein-energy malnutrition
0.000 0.946 0.054
E43 Unspecified severe protein-energy malnutrition
0.000 0.946 0.054
E42 Marasmic kwashiorkor
0.000 0.946 0.054
E41 Nutritional marasmus
0.000 0.946 0.054
E40 Kwashiorkor
0.000 0.946 0.054
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.946 0.054
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.946 0.054
E70.3 Albinism
0.000 0.946 0.054
E70.2 Disorders of tyrosine metabolism
0.000 0.946 0.054
E70.1 Other hyperphenylalaninaemias
0.000 0.946 0.054
E70.0 Classical phenylketonuria
0.000 0.946 0.054
E71.3 Disorders of fatty-acid metabolism
0.000 0.946 0.054
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.946 0.054
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.946 0.054
E71.0 Maple-syrup-urine disease
0.000 0.946 0.054
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.946 0.054
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.946 0.054
E72.5 Disorders of glycine metabolism
0.000 0.946 0.054
E72.4 Disorders of ornithine metabolism
0.000 0.946 0.054
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.946 0.054
E72.2 Disorders of urea cycle metabolism
0.000 0.946 0.054
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.946 0.054
E72.0 Disorders of amino-acid transport
0.000 0.946 0.054
E73.9 Lactose intolerance, unspecified
0.000 0.946 0.054
E73.8 Other lactose intolerance
0.000 0.946 0.054
E73.1 Secondary lactase deficiency
0.000 0.946 0.054
E73.0 Congenital lactase deficiency
0.000 0.946 0.054
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.946 0.054
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.946 0.054
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.946 0.054
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.946 0.054
E74.2 Disorders of galactose metabolism
0.000 0.946 0.054
E74.1 Disorders of fructose metabolism
0.000 0.946 0.054
E74.0 Glycogen storage disease
0.000 0.946 0.054
E75.6 Lipid storage disorder, unspecified
0.000 0.946 0.054
E75.5 Other lipid storage disorders
0.000 0.946 0.054
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.946 0.054
E75.3 Sphingolipidosis, unspecified
0.000 0.946 0.054
E75.2 Other sphingolipidosis
0.000 0.946 0.054
E75.1 Other gangliosidosis
0.000 0.946 0.054
E75.0 GM2 gangliosidosis
0.000 0.946 0.054
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.946 0.054
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.946 0.054
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.946 0.054
E76.2 Other mucopolysaccharidoses
0.000 0.946 0.054
E76.1 Mucopolysaccharidosis, type II
0.000 0.946 0.054
E76.0 Mucopolysaccharidosis, type I
0.000 0.946 0.054
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.946 0.054
E77.8 Other disorders of glycoprotein metabolism
0.000 0.946 0.054
E77.1 Defects in glycoprotein degradation
0.000 0.946 0.054
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.946 0.054
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.946 0.054
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.946 0.054
E79.1 Lesch-Nyhan syndrome
0.000 0.946 0.054
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.946 0.054
E84.9 Cystic fibrosis, unspecified
0.000 0.946 0.054
E84.8 Cystic fibrosis with other manifestations
0.000 0.946 0.054
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.946 0.054
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.946 0.054
E85.9 Amyloidosis, unspecified
0.000 0.946 0.054
E85.8 Other amyloidosis
0.000 0.946 0.054
E85.4 Organ-limited amyloidosis
0.000 0.946 0.054
E85.3 Secondary systemic amyloidosis
0.000 0.946 0.054
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.946 0.054
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.946 0.054
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.946 0.054
E11.8 With unspecified complications
0.000 0.947 0.053
E11.7 With multiple complications
0.000 0.947 0.053
E11.6 With other specified complications
0.000 0.947 0.053
E11.2 With renal complications
0.000 0.947 0.053
E11.1 With ketoacidosis
0.000 0.947 0.053
E11.0 With coma
0.000 0.947 0.053
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.947 0.052
E80.6 Other disorders of bilirubin metabolism
0.000 0.947 0.052
E80.5 Crigler-Najjar syndrome
0.000 0.947 0.052
E80.3 Defects of catalase and peroxydase
0.000 0.947 0.052
E80.2 Other porphyria
0.000 0.947 0.052
E80.1 Porphyria cutanea tarda
0.000 0.947 0.052
E80.0 Hereditary erythropoietic porphyria
0.000 0.947 0.052
E83.4 Disorders of magnesium metabolism
0.000 0.948 0.052
E61.1 Iron deficiency
0.000 0.948 0.052
E88.9 Metabolic disorder, unspecified
0.000 0.948 0.052
E88.8 Other specified metabolic disorders
0.000 0.948 0.052
E88.3 Tumour lysis syndrome
0.000 0.948 0.052
E88.2 Lipomatosis, not elsewhere classified
0.000 0.948 0.052
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.948 0.052
E12.9 Without complications
0.000 0.948 0.052
E12.8 With unspecified complications
0.000 0.948 0.052
E12.7 With multiple complications
0.000 0.948 0.052
E12.6 With other specified complications
0.000 0.948 0.052
E12.5 With peripheral circulatory complications
0.000 0.948 0.052
E12.4 With neurological complications
0.000 0.948 0.052
E12.3 With ophthalmic complications
0.000 0.948 0.052
E12.2 With renal complications
0.000 0.948 0.052
E12.1 With ketoacidosis
0.000 0.948 0.052
E12.0 With coma
0.000 0.948 0.052
E05.8 Other thyrotoxicosis
0.000 0.949 0.051
E05.5 Thyroid crisis or storm
0.000 0.949 0.051
E05.4 Thyrotoxicosis factitia
0.000 0.949 0.051
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.949 0.051
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.949 0.051
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.949 0.051
E80.4 Gilbert's syndrome
0.000 0.949 0.051
E13.8 With unspecified complications
0.000 0.950 0.050
E13.7 With multiple complications
0.000 0.950 0.050
E13.6 With other specified complications
0.000 0.950 0.050
E13.5 With peripheral circulatory complications
0.000 0.950 0.050
E13.4 With neurological complications
0.000 0.950 0.050
E13.3 With ophthalmic complications
0.000 0.950 0.050
E13.2 With renal complications
0.000 0.950 0.050
E13.1 With ketoacidosis
0.000 0.950 0.050
E13.0 With coma
0.000 0.950 0.050
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.950 0.050
E11.4 With neurological complications
0.000 0.950 0.050
E61.9 Deficiency of nutrient element, unspecified
0.000 0.950 0.049
E61.8 Deficiency of other specified nutrient elements
0.000 0.950 0.049
E61.7 Deficiency of multiple nutrient elements
0.000 0.950 0.049
E61.6 Vanadium deficiency
0.000 0.950 0.049
E61.5 Molybdenum deficiency
0.000 0.950 0.049
E61.4 Chromium deficiency
0.000 0.950 0.049
E61.3 Manganese deficiency
0.000 0.950 0.049
E61.2 Magnesium deficiency
0.000 0.950 0.049
E61.0 Copper deficiency
0.000 0.950 0.049
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.950 0.049
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.950 0.049
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.950 0.049
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.950 0.049
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.950 0.049
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.950 0.049
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.950 0.049
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.950 0.049
E06.9 Thyroiditis, unspecified
0.000 0.950 0.049
E06.5 Other chronic thyroiditis
0.000 0.950 0.049
E06.4 Drug-induced thyroiditis
0.000 0.950 0.049
E06.3 Autoimmune thyroiditis
0.000 0.950 0.049
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.950 0.049
E06.1 Subacute thyroiditis
0.000 0.950 0.049
E06.0 Acute thyroiditis
0.000 0.950 0.049
E67 Other hyperalimentation
0.000 0.951 0.049
E68 Sequelae of hyperalimentation
0.000 0.951 0.049
E65 Localised adiposity
0.000 0.951 0.049
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.951 0.049
E50.9 Vitamin A deficiency, unspecified
0.000 0.952 0.048
E50.8 Other manifestations of vitamin A deficiency
0.000 0.952 0.048
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.952 0.048
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.952 0.048
E50.5 Vitamin A deficiency with night blindness
0.000 0.952 0.048
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.952 0.048
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.952 0.048
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.952 0.048
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.952 0.048
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.952 0.048
E51.9 Thiamine deficiency, unspecified
0.000 0.952 0.048
E51.8 Other manifestations of thiamine deficiency
0.000 0.952 0.048
E51.2 Wernicke's encephalopathy
0.000 0.952 0.048
E51.1 Beriberi
0.000 0.952 0.048
E56.9 Vitamin deficiency, unspecified
0.000 0.952 0.048
E56.8 Deficiency of other vitamins
0.000 0.952 0.048
E56.1 Deficiency of vitamin K
0.000 0.952 0.048
E56.0 Deficiency of vitamin E
0.000 0.952 0.048
E63.9 Nutritional deficiency, unspecified
0.000 0.952 0.048
E63.8 Other specified nutritional deficiencies
0.000 0.952 0.048
E63.1 Imbalance of constituents of food intake
0.000 0.952 0.048
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.952 0.048
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.952 0.048
E64.8 Sequelae of other nutritional deficiencies
0.000 0.952 0.048
E64.3 Sequelae of rickets
0.000 0.952 0.048
E64.2 Sequelae of vitamin C deficiency
0.000 0.952 0.048
E64.1 Sequelae of vitamin A deficiency
0.000 0.952 0.048
E64.0 Sequelae of protein-energy malnutrition
0.000 0.952 0.048
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.952 0.048
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.952 0.048
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.952 0.048
E89.5 Postprocedural testicular hypofunction
0.000 0.952 0.048
E89.4 Postprocedural ovarian failure
0.000 0.952 0.048
E89.3 Postprocedural hypopituitarism
0.000 0.952 0.048
E89.2 Postprocedural hypoparathyroidism
0.000 0.952 0.048
E89.1 Postprocedural hypoinsulinaemia
0.000 0.952 0.048
E13.9 Without complications
0.000 0.952 0.047
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.954 0.046
E83.8 Other disorders of mineral metabolism
0.000 0.954 0.046
E83.2 Disorders of zinc metabolism
0.000 0.954 0.046
E83.0 Disorders of copper metabolism
0.000 0.954 0.046
E83.3 Disorders of phosphorus metabolism
0.000 0.954 0.046
E55.0 Rickets, active
0.000 0.955 0.045
E04.1 Non-toxic single thyroid nodule
0.000 0.955 0.045
E23 Hypofunction and other disorders of pituitary gland
0.000 0.956 0.043
E04.8 Other specified non-toxic goitre
0.000 0.957 0.043
E04.0 Non-toxic diffuse goitre
0.000 0.957 0.043
M17 Gonarthrosis [arthrosis of knee]
0.000 0.957 0.043
E66 Obesity
0.000 0.957 0.043
E11.9 Without complications
0.000 0.958 0.042
E29 Testicular dysfunction
0.000 0.959 0.041
E55.9 Vitamin D deficiency, unspecified
0.000 0.959 0.040
E89.0 Postprocedural hypothyroidism
0.000 0.960 0.039
E83.1 Disorders of iron metabolism
0.000 0.961 0.039
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.961 0.039
E34 Other endocrine disorders
0.000 0.961 0.039
E32 Diseases of thymus
0.000 0.961 0.039
E31 Polyglandular dysfunction
0.000 0.961 0.039
E30 Disorders of puberty, not elsewhere classified
0.000 0.961 0.039
E25 Adrenogenital disorders
0.000 0.961 0.039
E22 Hyperfunction of pituitary gland
0.000 0.961 0.039
E20 Hypoparathyroidism
0.000 0.961 0.039
E44.1 Mild protein-energy malnutrition
0.000 0.961 0.039
E44.0 Moderate protein-energy malnutrition
0.000 0.961 0.039
E28 Ovarian dysfunction
0.000 0.962 0.038
M15-M19 Arthrosis
0.000 0.962 0.038
E04.2 Non-toxic multinodular goitre
0.000 0.963 0.037
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.963 0.036
E24 Cushing's syndrome
0.000 0.963 0.036
E04.9 Non-toxic goitre, unspecified
0.000 0.964 0.036
E23.0 Hypopituitarism
0.000 0.964 0.036
E67.8 Other specified hyperalimentation
0.000 0.964 0.035
E67.3 Hypervitaminosis D
0.000 0.964 0.035
E67.2 Megavitamin-B6 syndrome
0.000 0.964 0.035
E67.1 Hypercarotenaemia
0.000 0.964 0.035
E67.0 Hypervitaminosis A
0.000 0.964 0.035
E83.5 Disorders of calcium metabolism
0.000 0.965 0.035
J45.9 Asthma, unspecified
0.000 0.967 0.033
I67 Other cerebrovascular diseases
0.000 0.967 0.033
I67.8 Other specified cerebrovascular diseases
0.000 0.967 0.033
M16 Coxarthrosis [arthrosis of hip]
0.000 0.967 0.033
E26 Hyperaldosteronism
0.001 0.967 0.032
E66.9 Obesity, unspecified
0.000 0.968 0.032
M19 Other arthrosis
0.000 0.968 0.032
E23.7 Disorder of pituitary gland, unspecified
0.000 0.968 0.031
E23.6 Other disorders of pituitary gland
0.000 0.968 0.031
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.968 0.031
E23.2 Diabetes insipidus
0.000 0.968 0.031
E23.1 Drug-induced hypopituitarism
0.000 0.968 0.031
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.968 0.032
E29.1 Testicular hypofunction
0.000 0.969 0.031
M17.5 Other secondary gonarthrosis
0.000 0.969 0.031
M17.4 Other secondary gonarthrosis, bilateral
0.000 0.969 0.031
M17.2 Posttraumatic gonarthrosis, bilateral
0.000 0.969 0.031
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.969 0.031
E66.1 Drug-induced obesity
0.000 0.969 0.031
E66.0 Obesity due to excess calories
0.000 0.969 0.031
I67.9 Cerebrovascular disease, unspecified
0.000 0.969 0.031
M05-M14 Inflammatory polyarthropathies
0.000 0.969 0.031
E29.9 Testicular dysfunction, unspecified
0.000 0.970 0.029
E29.8 Other testicular dysfunction
0.000 0.970 0.029
E29.0 Testicular hyperfunction
0.000 0.970 0.029
I67.1 Cerebral aneurysm, nonruptured
0.000 0.970 0.030
J45 Asthma
0.000 0.971 0.029
M17.3 Other posttraumatic gonarthrosis
0.000 0.971 0.029
M20.4 Other hammer toe(s) (acquired)
0.000 0.971 0.029
E20.9 Hypoparathyroidism, unspecified
0.000 0.972 0.028
E20.8 Other hypoparathyroidism
0.000 0.972 0.028
E20.1 Pseudohypoparathyroidism
0.000 0.972 0.028
E20.0 Idiopathic hypoparathyroidism
0.000 0.972 0.028
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.972 0.028
E22.8 Other hyperfunction of pituitary gland
0.000 0.972 0.028
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.972 0.028
E22.1 Hyperprolactinaemia
0.000 0.972 0.028
E22.0 Acromegaly and pituitary gigantism
0.000 0.972 0.028
E25.9 Adrenogenital disorder, unspecified
0.000 0.972 0.028
E25.8 Other adrenogenital disorders
0.000 0.972 0.028
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.972 0.028
E30.9 Disorder of puberty, unspecified
0.000 0.972 0.028
E30.8 Other disorders of puberty
0.000 0.972 0.028
E30.1 Precocious puberty
0.000 0.972 0.028
E30.0 Delayed puberty
0.000 0.972 0.028
E31.9 Polyglandular dysfunction, unspecified
0.000 0.972 0.028
E31.8 Other polyglandular dysfunction
0.000 0.972 0.028
E31.1 Polyglandular hyperfunction
0.000 0.972 0.028
E31.0 Autoimmune polyglandular failure
0.000 0.972 0.028
E32.9 Disease of thymus, unspecified
0.000 0.972 0.028
E32.8 Other diseases of thymus
0.000 0.972 0.028
E32.1 Abscess of thymus
0.000 0.972 0.028
E32.0 Persistent hyperplasia of thymus
0.000 0.972 0.028
E34.9 Endocrine disorder, unspecified
0.000 0.972 0.028
E34.8 Other specified endocrine disorders
0.000 0.972 0.028
E34.5 Androgen resistance syndrome
0.000 0.972 0.028
E34.4 Constitutional tall stature
0.000 0.972 0.028
E34.3 Short stature, not elsewhere classified
0.000 0.972 0.028
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.972 0.028
E34.1 Other hypersecretion of intestinal hormones
0.000 0.972 0.028
E34.0 Carcinoid syndrome
0.000 0.972 0.028
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.972 0.028
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.972 0.028
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.972 0.028
J22 Unspecified acute lower respiratory infection
0.000 0.972 0.028
M06 Other rheumatoid arthritis
0.000 0.972 0.028
E28.9 Ovarian dysfunction, unspecified
0.000 0.972 0.027
E28.8 Other ovarian dysfunction
0.000 0.972 0.027
E28.3 Primary ovarian failure
0.000 0.972 0.027
E28.1 Androgen excess
0.000 0.972 0.027
E28.0 Oestrogen excess
0.000 0.972 0.027
M19.9 Arthrosis, unspecified
0.000 0.972 0.028
E27 Other disorders of adrenal gland
0.000 0.972 0.027
M15 Polyarthrosis
0.000 0.972 0.027
M17.1 Other primary gonarthrosis
0.000 0.973 0.027
J45.0 Predominantly allergic asthma
0.000 0.973 0.027
M16.1 Other primary coxarthrosis
0.000 0.973 0.027
M70-M79 Other soft tissue disorders
0.000 0.973 0.027
I67.2 Cerebral atherosclerosis
0.000 0.973 0.027
E28.2 Polycystic ovarian syndrome
0.000 0.973 0.027
M06.9 Rheumatoid arthritis, unspecified
0.000 0.973 0.027
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.973 0.026
E21.4 Other specified disorders of parathyroid gland
0.000 0.973 0.026
E21.2 Other hyperparathyroidism
0.000 0.973 0.026
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.973 0.026
E24.8 Other Cushing's syndrome
0.000 0.973 0.026
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.973 0.026
E24.3 Ectopic ACTH syndrome
0.000 0.973 0.026
E24.2 Drug-induced Cushing's syndrome
0.000 0.973 0.026
E24.1 Nelson's syndrome
0.000 0.973 0.026
E24.0 Pituitary-dependent Cushing's disease
0.000 0.973 0.026
M20-M25 Other joint disorders
0.000 0.974 0.026
E21.3 Hyperparathyroidism, unspecified
0.000 0.974 0.025
M16.9 Coxarthrosis, unspecified
0.000 0.974 0.026
M13 Other arthritis
0.000 0.975 0.025
E21.0 Primary hyperparathyroidism
0.000 0.975 0.025
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.975 0.025
M23 Internal derangement of knee
0.000 0.975 0.025
M19.94 Arthrosis, unspecified (Hand)
0.000 0.975 0.025
M11 Other crystal arthropathies
0.000 0.975 0.025
M23.8 Other internal derangements of knee
0.000 0.976 0.024
M16.0 Primary coxarthrosis, bilateral
0.000 0.976 0.024
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.976 0.024
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.976 0.024
I67.5 Moyamoya disease
0.000 0.976 0.024
I67.4 Hypertensive encephalopathy
0.000 0.976 0.024
I67.3 Progressive vascular leukoencephalopathy
0.000 0.976 0.024
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.976 0.024
E24.9 Cushing's syndrome, unspecified
0.000 0.976 0.023
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.000 0.976 0.024
M16.7 Other secondary coxarthrosis
0.000 0.976 0.023
M16.6 Other secondary coxarthrosis, bilateral
0.000 0.976 0.023
M16.5 Other posttraumatic coxarthrosis
0.000 0.976 0.023
M16.4 Posttraumatic coxarthrosis, bilateral
0.000 0.976 0.023
M16.3 Other dysplastic coxarthrosis
0.000 0.976 0.023
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.000 0.976 0.023
E26.9 Hyperaldosteronism, unspecified
0.001 0.976 0.023
E26.8 Other hyperaldosteronism
0.001 0.976 0.023
E26.1 Secondary hyperaldosteronism
0.001 0.976 0.023
M20 Acquired deformities of fingers and toes
0.000 0.976 0.024
M19.90 Arthrosis, unspecified (Multiple sites)
0.000 0.976 0.023
M23.3 Other meniscus derangements
0.000 0.977 0.023
M50-M54 Other dorsopathies
0.000 0.977 0.023
M07 Psoriatic and enteropathic arthropathies
0.000 0.977 0.023
M19.96 Arthrosis, unspecified-Lower leg
0.000 0.977 0.023
M79.86 Other specified soft tissue disorders (Lower leg)
0.000 0.977 0.023
M05 Seropositive rheumatoid arthritis
0.000 0.977 0.023
M19.8 Other specified arthrosis
0.000 0.977 0.023
M19.2 Other secondary arthrosis
0.000 0.977 0.023
M19.1 Posttraumatic arthrosis of other joints
0.000 0.977 0.023
M60-M63 Disorders of muscles
0.000 0.977 0.023
M00-M03 Infectious arthropathies
0.000 0.977 0.023
M75 Shoulder lesions
0.000 0.977 0.023
I60-I69 Cerebrovascular diseases
0.000 0.977 0.023
J20-J22 Other acute lower respiratory infections
0.000 0.977 0.023
E66.8 Other obesity
0.000 0.977 0.022
M13.9 Arthritis, unspecified
0.000 0.978 0.022
M75.4 Impingement syndrome of shoulder
0.000 0.978 0.022
M14 Arthropathies in other diseases classified elsewhere
0.000 0.978 0.022
M12 Other specific arthropathies
0.000 0.978 0.022
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.978 0.022
M08 Juvenile arthritis
0.000 0.978 0.022
M19.99 Arthrosis, unspecified (Site unspecified)
0.000 0.978 0.022
M17.0 Primary gonarthrosis, bilateral
0.000 0.978 0.022
M79.8 Other specified soft tissue disorders
0.000 0.978 0.022
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.978 0.022
M79 Other soft tissue disorders, not elsewhere classified
0.000 0.978 0.022
M18 Arthrosis of first carpometacarpal joint
0.000 0.978 0.021
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.000 0.978 0.022
M80-M85 Disorders of bone density and structure
0.000 0.979 0.021
M91-M94 Chondropathies
0.000 0.979 0.021
M19.0 Primary arthrosis of other joints
0.000 0.979 0.021
M19.93 Arthrosis, unspecified (Forearm)
0.000 0.979 0.021
J45.8 Mixed asthma
0.000 0.979 0.021
J45.1 Nonallergic asthma
0.000 0.979 0.021
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.979 0.021
M86-M90 Other osteopathies
0.000 0.979 0.021
M72 Fibroblastic disorders
0.000 0.979 0.021

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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