TreeWAS – Variant ID: rs12413355

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E21.0 Primary hyperparathyroidism	0.000	0.743	0.257
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.760	0.240
E21.3 Hyperparathyroidism, unspecified	0.000	0.763	0.237
E21.4 Other specified disorders of parathyroid gland	0.000	0.820	0.180
E21.2 Other hyperparathyroidism	0.000	0.834	0.165
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.835	0.165
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.855	0.145
E20-E35 Disorders of other endocrine glands	0.000	0.874	0.126
E27 Other disorders of adrenal gland	0.000	0.888	0.112
E23 Hypofunction and other disorders of pituitary gland	0.000	0.889	0.111
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.892	0.108
E24 Cushing's syndrome	0.000	0.898	0.102
E23.0 Hypopituitarism	0.000	0.900	0.100
E20 Hypoparathyroidism	0.000	0.909	0.091
E27.1 Primary adrenocortical insufficiency	0.000	0.909	0.091
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.910	0.090
E30 Disorders of puberty, not elsewhere classified	0.000	0.910	0.090
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.911	0.089
E32 Diseases of thymus	0.000	0.912	0.088
E31 Polyglandular dysfunction	0.000	0.912	0.088
E24.2 Drug-induced Cushing's syndrome	0.000	0.917	0.083
E34 Other endocrine disorders	0.000	0.918	0.082
E25 Adrenogenital disorders	0.000	0.918	0.082
E29 Testicular dysfunction	0.000	0.918	0.082
E23.2 Diabetes insipidus	0.000	0.919	0.081
E24.0 Pituitary-dependent Cushing's disease	0.000	0.919	0.081
E27.5 Adrenomedullary hyperfunction	0.000	0.919	0.080
E27.0 Other adrenocortical overactivity	0.000	0.919	0.080
E23.1 Drug-induced hypopituitarism	0.000	0.920	0.080
E26 Hyperaldosteronism	0.000	0.921	0.079
E23.6 Other disorders of pituitary gland	0.000	0.923	0.077
E27.8 Other specified disorders of adrenal gland	0.000	0.924	0.076
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.927	0.073
E24.3 Ectopic ACTH syndrome	0.000	0.927	0.073
E24.1 Nelson's syndrome	0.000	0.927	0.073
E20.9 Hypoparathyroidism, unspecified	0.000	0.927	0.073
E24.8 Other Cushing's syndrome	0.000	0.928	0.072
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.929	0.071
E27.9 Disorder of adrenal gland, unspecified	0.000	0.929	0.071
E23.7 Disorder of pituitary gland, unspecified	0.000	0.931	0.069
E34.8 Other specified endocrine disorders	0.000	0.932	0.068
E24.9 Cushing's syndrome, unspecified	0.000	0.933	0.067
E20.0 Idiopathic hypoparathyroidism	0.000	0.934	0.066
E30.9 Disorder of puberty, unspecified	0.000	0.935	0.065
E30.8 Other disorders of puberty	0.000	0.935	0.065
E30.1 Precocious puberty	0.000	0.935	0.065
E30.0 Delayed puberty	0.000	0.935	0.065
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.935	0.065
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.935	0.065
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.935	0.065
E27.2 Addisonian crisis	0.000	0.936	0.064
E29.9 Testicular dysfunction, unspecified	0.000	0.936	0.063
E20.8 Other hypoparathyroidism	0.000	0.937	0.063
E32.8 Other diseases of thymus	0.000	0.937	0.063
E32.1 Abscess of thymus	0.000	0.937	0.063
E32.0 Persistent hyperplasia of thymus	0.000	0.937	0.063
E31.9 Polyglandular dysfunction, unspecified	0.000	0.937	0.063
E31.8 Other polyglandular dysfunction	0.000	0.937	0.063
E31.1 Polyglandular hyperfunction	0.000	0.937	0.063
E32.9 Disease of thymus, unspecified	0.000	0.939	0.061
E31.0 Autoimmune polyglandular failure	0.000	0.939	0.061
E34.3 Short stature, not elsewhere classified	0.000	0.939	0.060
E20.1 Pseudohypoparathyroidism	0.000	0.939	0.060
E28 Ovarian dysfunction	0.000	0.940	0.060
E34.5 Androgen resistance syndrome	0.000	0.941	0.059
E34.4 Constitutional tall stature	0.000	0.941	0.059
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.941	0.059
E34.1 Other hypersecretion of intestinal hormones	0.000	0.941	0.059
E25.9 Adrenogenital disorder, unspecified	0.000	0.941	0.059
E25.8 Other adrenogenital disorders	0.000	0.941	0.059
E29.8 Other testicular dysfunction	0.000	0.941	0.059
E29.0 Testicular hyperfunction	0.000	0.941	0.059
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.942	0.058
E26.8 Other hyperaldosteronism	0.000	0.943	0.057
E26.1 Secondary hyperaldosteronism	0.000	0.943	0.057
E26.9 Hyperaldosteronism, unspecified	0.000	0.945	0.055
E22 Hyperfunction of pituitary gland	0.000	0.949	0.051
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.949	0.051
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.949	0.050
E00-E07 Disorders of thyroid gland	0.000	0.949	0.051
E50-E64 Other nutritional deficiencies	0.000	0.950	0.050
E04.2 Non-toxic multinodular goitre	0.000	0.950	0.050
E04 Other non-toxic goitre	0.000	0.950	0.050
E26.0 Primary hyperaldosteronism	0.000	0.952	0.048
E34.9 Endocrine disorder, unspecified	0.000	0.952	0.048
E55 Vitamin D deficiency	0.000	0.952	0.048
E55.9 Vitamin D deficiency, unspecified	0.000	0.953	0.047
E16 Other disorders of pancreatic internal secretion	0.000	0.954	0.046
E07 Other disorders of thyroid	0.000	0.954	0.046
E34.0 Carcinoid syndrome	0.000	0.954	0.046
E16.2 Hypoglycaemia, unspecified	0.000	0.956	0.044
E28.9 Ovarian dysfunction, unspecified	0.000	0.957	0.043
E28.8 Other ovarian dysfunction	0.000	0.957	0.043
E28.1 Androgen excess	0.000	0.957	0.043
E28.0 Oestrogen excess	0.000	0.957	0.043
Y45.0 Opioids and related analgesics	0.000	0.957	0.043
E29.1 Testicular hypofunction	0.000	0.958	0.042
E40-E46 Malnutrition	0.000	0.960	0.040
E04.0 Non-toxic diffuse goitre	0.000	0.960	0.040
E07.9 Disorder of thyroid, unspecified	0.000	0.960	0.040
E56 Other vitamin deficiencies	0.000	0.960	0.040
E04.1 Non-toxic single thyroid nodule	0.000	0.960	0.040
E07.8 Other specified disorders of thyroid	0.000	0.962	0.038
E22.8 Other hyperfunction of pituitary gland	0.000	0.963	0.037
E15 Nondiabetic hypoglycaemic coma	0.000	0.963	0.037
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.963	0.037
E00 Congenital iodine-deficiency syndrome	0.000	0.963	0.037
E51 Thiamine deficiency	0.000	0.964	0.036
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.964	0.036
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.964	0.036
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.964	0.036
E50 Vitamin A deficiency	0.000	0.964	0.036
E60 Dietary zinc deficiency	0.000	0.964	0.036
E59 Dietary selenium deficiency	0.000	0.964	0.036
E52 Niacin deficiency [pellagra]	0.000	0.964	0.036
E04.8 Other specified non-toxic goitre	0.000	0.964	0.036
E63 Other nutritional deficiencies	0.000	0.964	0.036
E10-E14 Diabetes mellitus	0.000	0.965	0.035
E53 Deficiency of other B group vitamins	0.000	0.965	0.035
E16.1 Other hypoglycaemia	0.000	0.965	0.035
E28.2 Polycystic ovarian syndrome	0.000	0.965	0.035
E55.0 Rickets, active	0.000	0.965	0.034
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.000	0.966	0.034
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.967	0.033
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.967	0.033
E16.4 Abnormal secretion of gastrin	0.000	0.967	0.033
E16.3 Increased secretion of glucagon	0.000	0.967	0.033
E07.1 Dyshormogenetic goitre	0.000	0.967	0.033
E07.0 Hypersecretion of calcitonin	0.000	0.967	0.033
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.967	0.033
E56.1 Deficiency of vitamin K	0.000	0.967	0.033
E06 Thyroiditis	0.000	0.967	0.033
E58 Dietary calcium deficiency	0.000	0.967	0.032
E54 Ascorbic acid deficiency	0.000	0.967	0.032
E13 Other specified diabetes mellitus	0.000	0.969	0.031
E65-E68 Obesity and other hyperalimentation	0.000	0.969	0.031
E22.0 Acromegaly and pituitary gigantism	0.000	0.969	0.030
Y45.5 4-Aminophenol derivatives	0.000	0.971	0.029
E61 Deficiency of other nutrient elements	0.000	0.971	0.029
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.971	0.029
E45 Retarded development following protein-energy malnutrition	0.000	0.971	0.029
E43 Unspecified severe protein-energy malnutrition	0.000	0.971	0.029
E42 Marasmic kwashiorkor	0.000	0.971	0.029
E41 Nutritional marasmus	0.000	0.971	0.029
E40 Kwashiorkor	0.000	0.971	0.029
E28.3 Primary ovarian failure	0.000	0.971	0.029
E56.9 Vitamin deficiency, unspecified	0.000	0.971	0.029
E56.8 Deficiency of other vitamins	0.000	0.971	0.029
E56.0 Deficiency of vitamin E	0.000	0.971	0.029
E53.9 Vitamin B deficiency, unspecified	0.000	0.972	0.028
Y45.2 Propionic acid derivatives	0.000	0.972	0.028
E46 Unspecified protein-energy malnutrition	0.000	0.972	0.028
E10 Insulin-dependent diabetes mellitus	0.000	0.973	0.027
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.973	0.027
E10.2 With renal complications	0.000	0.973	0.027
Y45.8 Other analgesics and antipyretics	0.000	0.973	0.027
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.973	0.026
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.973	0.026
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.973	0.026
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.973	0.026
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.973	0.026
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.973	0.026
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.973	0.026
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.973	0.026
E51.2 Wernicke's encephalopathy	0.000	0.974	0.026
Y45.1 Salicylates	0.000	0.974	0.026
E51.9 Thiamine deficiency, unspecified	0.000	0.974	0.026
E51.8 Other manifestations of thiamine deficiency	0.000	0.974	0.026
E51.1 Beriberi	0.000	0.974	0.026
E50.9 Vitamin A deficiency, unspecified	0.000	0.974	0.026
E50.8 Other manifestations of vitamin A deficiency	0.000	0.974	0.026
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.974	0.026
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.974	0.026
E50.5 Vitamin A deficiency with night blindness	0.000	0.974	0.026
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.974	0.026
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.974	0.026
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.974	0.026
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.974	0.026
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.974	0.026
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.974	0.026
E64.8 Sequelae of other nutritional deficiencies	0.000	0.974	0.026
E64.3 Sequelae of rickets	0.000	0.974	0.026
E64.2 Sequelae of vitamin C deficiency	0.000	0.974	0.026
E64.1 Sequelae of vitamin A deficiency	0.000	0.974	0.026
E64.0 Sequelae of protein-energy malnutrition	0.000	0.974	0.026
E63.8 Other specified nutritional deficiencies	0.000	0.974	0.026
E63.1 Imbalance of constituents of food intake	0.000	0.974	0.026
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.974	0.026
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.000	0.974	0.026
E13.3 With ophthalmic complications	0.000	0.974	0.026
E12 Malnutrition-related diabetes mellitus	0.000	0.974	0.025
E63.9 Nutritional deficiency, unspecified	0.000	0.975	0.025
E53.1 Pyridoxine deficiency	0.000	0.975	0.025
E53.0 Riboflavin deficiency	0.000	0.975	0.025
E13.9 Without complications	0.000	0.975	0.025
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.975	0.025
E65 Localised adiposity	0.000	0.975	0.025
E06.9 Thyroiditis, unspecified	0.000	0.976	0.024
E22.1 Hyperprolactinaemia	0.000	0.976	0.023
E06.4 Drug-induced thyroiditis	0.000	0.976	0.023
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.976	0.023
E06.0 Acute thyroiditis	0.000	0.976	0.023
E10.4 With neurological complications	0.000	0.977	0.023
Y45.4 Antirheumatics	0.000	0.977	0.023
E06.5 Other chronic thyroiditis	0.000	0.977	0.023
E06.1 Subacute thyroiditis	0.000	0.977	0.023
E13.8 With unspecified complications	0.000	0.978	0.022
E13.7 With multiple complications	0.000	0.978	0.022
E13.6 With other specified complications	0.000	0.978	0.022
E13.5 With peripheral circulatory complications	0.000	0.978	0.022
E13.4 With neurological complications	0.000	0.978	0.022
E13.2 With renal complications	0.000	0.978	0.022
E13.1 With ketoacidosis	0.000	0.978	0.022
E13.0 With coma	0.000	0.978	0.022
E67 Other hyperalimentation	0.000	0.978	0.022
E68 Sequelae of hyperalimentation	0.000	0.978	0.022
E61.9 Deficiency of nutrient element, unspecified	0.000	0.979	0.021
E61.8 Deficiency of other specified nutrient elements	0.000	0.979	0.021
E61.7 Deficiency of multiple nutrient elements	0.000	0.979	0.021
E61.6 Vanadium deficiency	0.000	0.979	0.021
E61.5 Molybdenum deficiency	0.000	0.979	0.021
E61.4 Chromium deficiency	0.000	0.979	0.021
E61.3 Manganese deficiency	0.000	0.979	0.021
E61.0 Copper deficiency	0.000	0.979	0.021
E44.1 Mild protein-energy malnutrition	0.000	0.979	0.021
E44.0 Moderate protein-energy malnutrition	0.000	0.979	0.021
E04.9 Non-toxic goitre, unspecified	0.000	0.979	0.021
E06.3 Autoimmune thyroiditis	0.000	0.979	0.021
E10.0 With coma	0.000	0.980	0.020
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.980	0.020
E10.6 With other specified complications	0.000	0.980	0.020
E53.8 Deficiency of other specified B group vitamins	0.000	0.980	0.020
E11 Non-insulin-dependent diabetes mellitus	0.000	0.980	0.020
E61.1 Iron deficiency	0.000	0.981	0.019
E10.7 With multiple complications	0.000	0.981	0.019
E12.9 Without complications	0.000	0.981	0.018
E12.8 With unspecified complications	0.000	0.981	0.018
E12.7 With multiple complications	0.000	0.981	0.018
E12.6 With other specified complications	0.000	0.981	0.018
E12.5 With peripheral circulatory complications	0.000	0.981	0.018
E12.4 With neurological complications	0.000	0.981	0.018
E12.3 With ophthalmic complications	0.000	0.981	0.018
E12.2 With renal complications	0.000	0.981	0.018
E12.1 With ketoacidosis	0.000	0.981	0.018
E12.0 With coma	0.000	0.981	0.018
E11.5 With peripheral circulatory complications	0.000	0.981	0.019
E11.0 With coma	0.000	0.982	0.018
E10.3 With ophthalmic complications	0.000	0.982	0.018
E61.2 Magnesium deficiency	0.000	0.982	0.017
E10.1 With ketoacidosis	0.000	0.983	0.017
E03 Other hypothyroidism	0.000	0.983	0.017
E10.5 With peripheral circulatory complications	0.000	0.983	0.017
E67.8 Other specified hyperalimentation	0.000	0.984	0.016
E67.3 Hypervitaminosis D	0.000	0.984	0.016
E67.2 Megavitamin-B6 syndrome	0.000	0.984	0.016
E67.1 Hypercarotenaemia	0.000	0.984	0.016
E67.0 Hypervitaminosis A	0.000	0.984	0.016
E10.8 With unspecified complications	0.000	0.984	0.016
E11.1 With ketoacidosis	0.000	0.984	0.016
E11.8 With unspecified complications	0.000	0.984	0.016
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.985	0.015
E05.5 Thyroid crisis or storm	0.000	0.985	0.015
E05.4 Thyrotoxicosis factitia	0.000	0.985	0.015
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.985	0.015
E11.6 With other specified complications	0.000	0.985	0.015
E11.7 With multiple complications	0.000	0.986	0.014
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.986	0.014
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.986	0.014
E05.8 Other thyrotoxicosis	0.000	0.986	0.013
E03.5 Myxoedema coma	0.000	0.987	0.012
E03.4 Atrophy of thyroid (acquired)	0.000	0.987	0.012
E03.3 Postinfectious hypothyroidism	0.000	0.987	0.012
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.988	0.012
S56 Injury of muscle and tendon at forearm level	0.012	0.988	0.000
E03.8 Other specified hypothyroidism	0.000	0.988	0.012
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.988	0.012
E03.1 Congenital hypothyroidism without goitre	0.000	0.988	0.012
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.012	0.988	0.000
K37 Unspecified appendicitis	0.011	0.989	0.000
S51 Open wound of forearm	0.011	0.989	0.000
E11.2 With renal complications	0.000	0.989	0.010
S51.0 Open wound of elbow	0.011	0.989	0.000
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.010	0.990	0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.010	0.990	0.000
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.010	0.990	0.000
S56.5 Injury of other extensor muscle and tendon at forearm level	0.010	0.990	0.000
S50-S59 Injuries to the elbow and forearm	0.010	0.990	0.000
E14 Unspecified diabetes mellitus	0.000	0.990	0.010
S51.8 Open wound of other parts of forearm	0.009	0.991	0.000
E10.9 Without complications	0.000	0.991	0.009
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.009	0.991	0.000
S51.7 Multiple open wounds of forearm	0.009	0.991	0.000
S56.2 Injury of other flexor muscle and tendon at forearm level	0.009	0.991	0.000
S56.0 Injury of flexor muscle and tendon of thumb at forearm level	0.009	0.991	0.000
S56.7 Injury of multiple muscles and tendons at forearm level	0.009	0.991	0.000
S59 Other and unspecified injuries of forearm	0.008	0.992	0.000
S54 Injury of nerves at forearm level	0.008	0.992	0.000
E14.4 With neurological complications	0.000	0.992	0.008
S55 Injury of blood vessels at forearm level	0.008	0.992	0.000
S52.00 Fracture of upper end of ulna (closed)	0.008	0.992	0.000
E14.0 With coma	0.000	0.992	0.007
E14.2 Withrenal complications	0.000	0.993	0.007
S59.9 Unspecified injury of forearm	0.007	0.993	0.000
S58 Traumatic amputation of forearm	0.007	0.993	0.000
S57 Crushing injury of forearm	0.007	0.993	0.000
E14.7 With multiple complications	0.000	0.993	0.007
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.007	0.993	0.000
E14.5 With peripheral circulatory complications	0.000	0.993	0.007
E14.8 With unspecified complications	0.000	0.993	0.007
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.007	0.993	0.000
S54.0 Injury of ulnar nerve at forearm level	0.007	0.993	0.000
E14.6 With other specified complications	0.000	0.993	0.007
S56.20 Unspecified injury of other flexor muscle, fascia and tendon at forearm level	0.006	0.993	0.000
E11.3 With ophthalmic complications	0.000	0.994	0.006
S55.1 Injury of radial artery at forearm level	0.006	0.994	0.000
S59.8 Other specified injuries of forearm	0.006	0.994	0.000
S59.7 Multiple injuries of forearm	0.006	0.994	0.000
E11.4 With neurological complications	0.000	0.994	0.006
K55.9 Vascular disorder of intestine, unspecified	0.000	0.994	0.006
S51.9 Open wound of forearm, part unspecified	0.006	0.994	0.000
C67.9 Bladder, unspecified	0.006	0.994	0.000
E14.1 With ketoacidosis	0.000	0.994	0.006
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.006	0.994	0.000
S52.0 Fracture of upper end of ulna	0.006	0.994	0.000
S54.2 Injury of radial nerve at forearm level	0.006	0.994	0.000
S54.9 Injury of unspecified nerve at forearm level	0.006	0.994	0.000
S54.8 Injury of other nerves at forearm level	0.006	0.994	0.000
S54.7 Injury of multiple nerves at forearm level	0.006	0.994	0.000
S54.3 Injury of cutaneous sensory nerve at forearm level	0.006	0.994	0.000
S52 Fracture of forearm	0.006	0.994	0.000
S55.9 Injury of unspecified blood vessel at forearm level	0.006	0.994	0.000
S55.8 Injury of other blood vessels at forearm level	0.006	0.994	0.000
S55.7 Injury of multiple blood vessels at forearm level	0.006	0.994	0.000
S55.2 Injury of vein at forearm level	0.006	0.994	0.000
T17.2 Foreign body in pharynx	0.006	0.994	0.000
S54.1 Injury of median nerve at forearm level	0.006	0.994	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.006	0.994	0.000
S50 Superficial injury of forearm	0.006	0.994	0.000
S57.9 Crushing injury of forearm, part unspecified	0.005	0.994	0.000
S57.8 Crushing injury of forearm, part unspecified	0.005	0.994	0.000
S57.7 Crushing injury of other parts of forearm	0.005	0.994	0.000
S57.0 Crushing injury of elbow	0.005	0.994	0.000
S58.9 Traumatic amputation of forearm, level unspecified	0.005	0.994	0.000
S58.1 Traumatic amputation at level between elbow and wrist	0.005	0.994	0.000
S58.0 Traumatic amputation at elbow level	0.005	0.994	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.006	0.994	0.000
B44.1 Other pulmonary aspergillosis	0.000	0.994	0.006
S53.3 Traumatic rupture of ulnar collateral ligament	0.005	0.995	0.000
S55.0 Injury of ulnar artery at forearm level	0.005	0.995	0.000
S53.1 Dislocation of elbow, unspecified	0.005	0.995	0.000
S53.0 Dislocation of radial head	0.005	0.995	0.000
K63.2 Fistula of intestine	0.000	0.995	0.005
N48.6 Balanitis xerotica obliterans	0.005	0.995	0.000
S53.4 Sprain and strain of elbow	0.005	0.995	0.000
S53.2 Traumatic rupture of radial collateral ligament	0.005	0.995	0.000
K29.5 Chronic gastritis, unspecified	0.000	0.995	0.005
E05.9 Thyrotoxicosis, unspecified	0.000	0.995	0.005
Y49.2 Other and unspecified antidepressants	0.000	0.995	0.005
Q63.0 Accessory kidney	0.005	0.995	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.000	0.995	0.005
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.995	0.005
S52.3 Fracture of shaft of radius	0.005	0.995	0.000
H72.8 Other perforations of tympanic membrane	0.005	0.995	0.000
N80.8 Other endometriosis	0.000	0.995	0.005
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.005	0.995	0.000
S54.20 Injury of radial nerve at forearm level, unspecified arm	0.004	0.995	0.000
S50.1 Contusion of other and unspecified parts of forearm	0.004	0.995	0.000
L60.0 Ingrowing nail	0.000	0.995	0.005
S52.9 Fracture of forearm, part unspecified	0.004	0.996	0.000
S52.5 Fracture of lower end of radius	0.004	0.996	0.000
H52.2 Astigmatism	0.000	0.996	0.004
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.004	0.996	0.000
E14.3 With ophthalmic complications	0.000	0.996	0.004
S50.7 Multiple superficial injuries of forearm	0.004	0.996	0.000
C67 Malignant neoplasm of bladder	0.004	0.996	0.000
S53.11 Anterior subluxation and dislocation of ulnohumeral joint	0.004	0.996	0.000
S53.10 Unspecified subluxation and dislocation of ulnohumeral joint	0.004	0.996	0.000
S52.6 Fracture of lower end of both ulna and radius	0.004	0.996	0.000
A49.8 Other bacterial infections of unspecified site	0.000	0.996	0.004
S52.30 Fracture of shaft of radius (closed)	0.004	0.996	0.000
T17 Foreign body in respiratory tract	0.004	0.996	0.000
C67.4 Posterior wall of bladder	0.004	0.996	0.000
S50.9 Superficial injury of forearm, unspecified	0.004	0.996	0.000
S52.4 Fracture of shafts of both ulna and radius	0.004	0.996	0.000
S52.2 Fracture of shaft of ulna	0.004	0.996	0.000
Q63 Other congenital malformations of kidney	0.004	0.996	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.000	0.996	0.004
Q63.1 Lobulated, fused and horseshoe kidney	0.004	0.996	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.004	0.996	0.000
N76.2 Acute vulvitis	0.004	0.996	0.000
C67.3 Anterior wall of bladder	0.004	0.996	0.000
S50.8 Other superficial injuries of forearm	0.004	0.996	0.000
S52.31 Fracture of shaft of radius (open)	0.003	0.996	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.996	0.004
E66 Obesity	0.000	0.996	0.004
C67.6 Ureteric orifice	0.004	0.996	0.000
H72.0 Central perforation of tympanic membrane	0.004	0.996	0.000
S52.51 Fracture of lower end of radius (open)	0.004	0.996	0.000
S50.0 Contusion of elbow	0.003	0.996	0.000
S52.7 Multiple fractures of forearm	0.003	0.996	0.001
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.996	0.004
E89.2 Postprocedural hypoparathyroidism	0.000	0.996	0.004
S52.91 Fracture of forearm, part unspecified (open)	0.003	0.997	0.000
S52.90 Fracture of forearm, part unspecified (closed)	0.003	0.997	0.000
Y49.5 Other antipsychotics and neuroleptics	0.000	0.997	0.003
Y54.5 Other diuretics	0.000	0.997	0.003
H72 Perforation of tympanic membrane	0.003	0.997	0.000
D09.0 Bladder	0.003	0.997	0.000
S52.8 Fracture of other parts of forearm	0.003	0.997	0.000
C67.7 Urachus	0.003	0.997	0.000
S52.1 Fracture of upper end of radius	0.003	0.997	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
S52.01 Fracture of upper end of ulna (open)	0.003	0.997	0.000
S52.41 Fracture of shafts of both ulna and radius (open)	0.003	0.997	0.000
S52.50 Fracture of lower end of radius (closed)	0.003	0.997	0.000
C67.2 Lateral wall of bladder	0.003	0.997	0.000
T17.8 Foreign body in other and multiple parts of respiratory tract	0.003	0.997	0.000
T17.4 Foreign body in trachea	0.003	0.997	0.000
T17.1 Foreign body in nostril	0.003	0.997	0.000
T17.0 Foreign body in nasal sinus	0.003	0.997	0.000
Q63.8 Other specified congenital malformations of kidney	0.003	0.997	0.000
T17.5 Foreign body in bronchus	0.003	0.997	0.000
Q63.2 Ectopic kidney	0.003	0.997	0.000
C67.0 Trigone of bladder	0.003	0.997	0.000
C67.5 Bladder neck	0.003	0.997	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.003	0.997	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.003	0.997	0.000
Q63.3 Hyperplastic and giant kidney	0.003	0.997	0.000
Y49.9 Psychotropic drug, unspecified	0.000	0.997	0.003
Y49.7 Psychostimulants with abuse potential	0.000	0.997	0.003
Y49.6 Psychodysleptics [hallucinogens]	0.000	0.997	0.003
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.997	0.003
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.997	0.003
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
S52.21 Fracture of shaft of ulna (open)	0.003	0.997	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.997	0.003
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.997	0.003
Z93.3 Colostomy status	0.000	0.997	0.003
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.997	0.003
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.003	0.997	0.000
E66.0 Obesity due to excess calories	0.000	0.997	0.003
T17.3 Foreign body in larynx	0.003	0.997	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.000	0.997	0.003
E66.1 Drug-induced obesity	0.000	0.997	0.003
Q63.9 Congenital malformation of kidney, unspecified	0.003	0.997	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.003	0.997	0.000
S52.71 Multiple fractures of forearm (open)	0.002	0.997	0.000
C67.8 Overlapping lesion of bladder	0.003	0.997	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.997	0.003
B44 Aspergillosis	0.000	0.997	0.003
M77.12 Lateral epicondylitis (Upper arm)	0.000	0.997	0.003
H72.1 Attic perforation of tympanic membrane	0.003	0.997	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.000	0.997	0.003
C67.1 Dome of bladder	0.003	0.997	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.000	0.997	0.003
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.000	0.997	0.003
Q66.8 Other congenital deformities of feet	0.000	0.997	0.003
A49.0 Staphylococcal infection, unspecified	0.000	0.997	0.003
S52.20 Fracture of shaft of ulna (closed)	0.002	0.997	0.000
G30.9 Alzheimer's disease, unspecified	0.003	0.997	0.000
H72.2 Other marginal perforations of tympanic membrane	0.002	0.997	0.000
J95.8 Other postprocedural respiratory disorders	0.000	0.997	0.003
K65.9 Peritonitis, unspecified	0.000	0.997	0.003
S52.40 Fracture of shafts of both ulna and radius (closed)	0.002	0.997	0.000
S52.81 Fracture of other parts of forearm (open)	0.002	0.997	0.000
E89.4 Postprocedural ovarian failure	0.000	0.997	0.002
J98.0 Diseases of bronchus, not elsewhere classified	0.000	0.997	0.003
H69.8 Other specified disorders of Eustachian tube	0.002	0.997	0.000
K55.8 Other vascular disorders of intestine	0.000	0.997	0.002
Y54.7 Agents affecting calcification	0.000	0.998	0.002
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.000	0.998	0.002
Y54.0 Mineralocorticoids	0.000	0.998	0.002
S52.11 Fracture of upper end of radius (open)	0.002	0.998	0.000
O63.9 Long labour, unspecified	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.000	0.998	0.002
Y54.6 Electrolytic, caloric and water-balance agents	0.000	0.998	0.002
Y54.2 Carbonic-anhydrase inhibitors	0.000	0.998	0.002
Y54.4 Loop [high-ceiling] diuretics	0.000	0.998	0.002
B44.9 Aspergillosis, unspecified	0.000	0.998	0.002
Y59 Other and unspecified vaccines and biological substances	0.000	0.998	0.002
Y58 Bacterial vaccines	0.000	0.998	0.002
Y54.8 Agents affecting uric acid metabolism	0.000	0.998	0.002
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.000	0.998	0.002
C81.9 Hodgkin's disease, unspecified	0.002	0.998	0.000
K55 Vascular disorders of intestine	0.000	0.998	0.002
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.000	0.998	0.002
Y54.3 Benzothiadiazine derivatives	0.000	0.998	0.002
M25.84 Other specified joint disorders (Hand)	0.002	0.998	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.998	0.002
B44.7 Disseminated aspergillosis	0.000	0.998	0.002
B44.2 Tonsillar aspergillosis	0.000	0.998	0.002
B44.0 Invasive pulmonary aspergillosis	0.000	0.998	0.002
H69 Other disorders of Eustachian tube	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.000	0.998	0.002
E89.3 Postprocedural hypopituitarism	0.000	0.998	0.002
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.000	0.998	0.002
E70-E90 Metabolic disorders	0.000	0.998	0.002
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.000	0.998	0.002
D22.0 Melanocytic naevi of lip	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations