TreeWAS – Variant ID: rs12419342

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M16.9 Coxarthrosis, unspecified	0.000	0.837	0.163
H40.9 Glaucoma, unspecified	0.000	0.888	0.112
M16 Coxarthrosis [arthrosis of hip]	0.000	0.898	0.102
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.000	0.910	0.089
M16.7 Other secondary coxarthrosis	0.000	0.917	0.083
M16.5 Other posttraumatic coxarthrosis	0.000	0.925	0.075
M16.1 Other primary coxarthrosis	0.000	0.926	0.074
M16.4 Posttraumatic coxarthrosis, bilateral	0.000	0.926	0.074
M16.3 Other dysplastic coxarthrosis	0.000	0.927	0.073
M16.6 Other secondary coxarthrosis, bilateral	0.000	0.929	0.071
M16.0 Primary coxarthrosis, bilateral	0.000	0.938	0.062
H34.8 Other retinal vascular occlusions	0.000	0.952	0.048
M54.19 Radiculopathy (Site unspecified)	0.000	0.956	0.044
M54.1 Radiculopathy	0.000	0.957	0.043
M54.17 Radiculopathy (Lumbosacral region)	0.000	0.960	0.040
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.039	0.961	0.000
M54.16 Radiculopathy (Lumbar region)	0.000	0.963	0.037
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.037	0.963	0.000
M54.12 Radiculopathy (Cervical region)	0.000	0.964	0.036
T46 Poisoning by agents primarily affecting the cardiovascular system	0.035	0.965	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.035	0.965	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.034	0.966	0.000
M54.14 Radiculopathy (Thoracic region)	0.000	0.966	0.034
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.000	0.966	0.034
H34 Retinal vascular occlusions	0.000	0.967	0.033
T45.0 Antiallergic and antiemetic drugs	0.033	0.967	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.031	0.969	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.000	0.969	0.031
M54.15 Radiculopathy (Thoracolumbar region)	0.000	0.969	0.031
M54.13 Radiculopathy (Cervicothoracic region)	0.000	0.969	0.031
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.000	0.969	0.031
H34.2 Other retinal artery occlusions	0.000	0.971	0.029
T36 Poisoning by systemic antibiotics	0.029	0.971	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.029	0.971	0.000
T46.1 Calcium-channel blockers	0.029	0.971	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.028	0.972	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.028	0.972	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.028	0.972	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.028	0.972	0.000
T45.5 Anticoagulants	0.027	0.972	0.000
T38.0 Glucocorticoids and synthetic analogues	0.027	0.972	0.000
T40.4 Other synthetic narcotics	0.027	0.973	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.027	0.973	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.027	0.973	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.027	0.973	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.027	0.973	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.027	0.973	0.000
T38.9 Other and unspecified hormone antagonists	0.026	0.973	0.000
T38.7 Androgens and anabolic congeners	0.026	0.973	0.000
T38.5 Other oestrogens and progestogens	0.026	0.973	0.000
T38.4 Oral contraceptives	0.026	0.973	0.000
T38.2 Antithyroid drugs	0.026	0.973	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.026	0.973	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.026	0.974	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.026	0.974	0.000
T45.4 Iron and its compounds	0.026	0.974	0.000
H34.9 Retinal vascular occlusion, unspecified	0.000	0.974	0.026
T46.8 Antivaricose drugs, including sclerosing agents	0.025	0.974	0.000
T46.7 Peripheral vasodilators	0.025	0.974	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.025	0.975	0.000
T38.1 Thyroid hormones and substitutes	0.025	0.975	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.025	0.975	0.000
T45.8 Other primarily systemic and haematological agents	0.025	0.975	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.025	0.975	0.000
T45.6 Fibrinolysis-affecting drugs	0.025	0.975	0.000
T45.3 Enzymes, not elsewhere classified	0.025	0.975	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.024	0.975	0.000
T39.0 Salicylates	0.025	0.975	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.024	0.976	0.000
H34.0 Transient retinal artery occlusion	0.000	0.976	0.024
H34.1 Central retinal artery occlusion	0.000	0.976	0.023
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.023	0.976	0.000
Z91.5 Personal history of self-harm	0.023	0.977	0.000
T36.3 Macrolides	0.022	0.978	0.000
T36.0 Penicillins	0.022	0.978	0.000
T40.3 Methadone	0.022	0.978	0.000
T40.5 Cocaine	0.022	0.978	0.000
T36.4 Tetracyclines	0.022	0.978	0.000
T36.8 Other systemic antibiotics	0.022	0.978	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.022	0.978	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.021	0.978	0.000
T36.9 Systemic antibiotic, unspecified	0.021	0.979	0.000
T36.7 Antifungal antibiotics, systemically used	0.021	0.979	0.000
T36.6 Rifamycins	0.021	0.979	0.000
T36.5 Aminoglycosides	0.021	0.979	0.000
T36.2 Chloramphenicol group	0.021	0.979	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.021	0.979	0.000
T45.2 Vitamins, not elsewhere classified	0.021	0.979	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.021	0.979	0.000
T40.8 Lysergide [LSD]	0.021	0.979	0.000
T40.7 Cannabis (derivatives)	0.021	0.979	0.000
T40.0 Opium	0.021	0.979	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.021	0.979	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.020	0.979	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.020	0.979	0.000
T41.2 Other and unspecified general anaesthetics	0.020	0.980	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.020	0.980	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.020	0.980	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.020	0.980	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.020	0.980	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.020	0.980	0.000
T44.0 Anticholinesterase agents	0.020	0.980	0.000
T40.1 Heroin	0.020	0.980	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.020	0.980	0.000
T49.9 Topical agent, unspecified	0.019	0.981	0.000
T49.8 Other topical agents	0.019	0.981	0.000
T49.7 Dental drugs, topically applied	0.019	0.981	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.019	0.981	0.000
T49.5 Ophthalmological drugs and preparations	0.019	0.981	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.019	0.981	0.000
T49.3 Emollients, demulcents and protectants	0.019	0.981	0.000
T49.2 Local astringents and local detergents	0.019	0.981	0.000
T49.1 Antipruritics	0.019	0.981	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.019	0.981	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.019	0.981	0.000
T37.5 Antiviral drugs	0.019	0.981	0.000
T37.4 Anthelminthics	0.019	0.981	0.000
T37.3 Other antiprotozoal drugs	0.019	0.981	0.000
T37.1 Antimycobacterial drugs	0.019	0.981	0.000
T37.0 Sulphonamides	0.019	0.981	0.000
T41.5 Therapeutic gases	0.019	0.981	0.000
T41.4 Anaesthetic, unspecified	0.019	0.981	0.000
T41.3 Local anaesthetics	0.019	0.981	0.000
T41.1 Intravenous anaesthetics	0.019	0.981	0.000
T41.0 Inhaled anaesthetics	0.019	0.981	0.000
T39.4 Antirheumatics, not elsewhere classified	0.019	0.981	0.000
T39.2 Pyrazolone derivatives	0.019	0.981	0.000
G81.9 Hemiplegia, unspecified	0.019	0.981	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.019	0.981	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.019	0.981	0.000
Z91 Personal history of risk-factors, not elsewhere classified	0.018	0.982	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.018	0.982	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.017	0.982	0.000
T40.6 Other and unspecified narcotics	0.017	0.982	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.017	0.983	0.000
T48.4 Expectorants	0.017	0.983	0.000
T48.3 Antitussives	0.017	0.983	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.017	0.983	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.017	0.983	0.000
T48.0 Oxytocic drugs	0.017	0.983	0.000
Z99.8 Dependence on other enabling machines and devices	0.000	0.983	0.017
T48.5 Anti-common-cold drugs	0.016	0.983	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.016	0.984	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.016	0.984	0.001
T43.6 Psychostimulants with abuse potential	0.016	0.984	0.000
T47.2 Stimulant laxatives	0.016	0.984	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.016	0.984	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.016	0.984	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.016	0.984	0.000
T47.7 Emetics	0.016	0.984	0.000
T47.5 Digestants	0.016	0.984	0.000
T47.3 Saline and osmotic laxatives	0.016	0.984	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.016	0.984	0.000
T43.2 Other and unspecified antidepressants	0.016	0.984	0.000
Z91.6 Personal history of other physical trauma	0.016	0.984	0.000
T47.4 Other laxatives	0.015	0.984	0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.016	0.984	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.015	0.985	0.000
Z91.2 Personal history of poor personal hygiene	0.015	0.985	0.000
T47.6 Antidiarrhoeal drugs	0.015	0.985	0.000
T42.1 Iminostilbenes	0.015	0.985	0.000
T42.3 Barbiturates	0.015	0.985	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.014	0.986	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.014	0.986	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.014	0.986	0.000
T47.0 Histamine H(2)-receptor antagonists	0.014	0.986	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.014	0.986	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.013	0.986	0.000
T42.2 Succinimides and oxazolidinediones	0.013	0.986	0.000
Z91.7 Personal history of female genital mutilation	0.013	0.987	0.000
Z91.3 Personal history of unhealthy sleep-wake schedule	0.013	0.987	0.000
T50.8 Diagnostic agents	0.012	0.987	0.001
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.013	0.987	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.013	0.987	0.000
T50.4 Drugs affecting uric acid metabolism	0.012	0.988	0.001
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.012	0.988	0.001
T43.9 Psychotropic drug, unspecified	0.012	0.988	0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified	0.012	0.988	0.000
T50.7 Analeptics and opioid receptor antagonists	0.011	0.988	0.001
T50.5 Appetite depressants	0.011	0.988	0.001
T50.3 Electrolytic, caloric and water-balance agents	0.011	0.988	0.001
T50.0 Mineralocorticoids and their antagonists	0.011	0.988	0.001
T50.1 Loop [high-ceiling] diuretics	0.011	0.988	0.001
R42 Dizziness and giddiness	0.012	0.988	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.012	0.988	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.000	0.988	0.012
Z99.1 Dependence on respirator	0.000	0.989	0.011
F05.9 Delirium, unspecified	0.000	0.989	0.011
T42.0 Hydantoin derivatives	0.011	0.989	0.000
G81 Hemiplegia	0.011	0.989	0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.011	0.989	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.010	0.990	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.009	0.990	0.001
Z99.3 Dependence on wheelchair	0.000	0.991	0.009
S82.20 Fracture of shaft of tibia (closed)	0.000	0.991	0.009
Z99.4 Dependence on artificial heart	0.000	0.991	0.009
Z99.0 Dependence on aspirator	0.000	0.991	0.009
G81.1 Spastic hemiplegia	0.008	0.992	0.000
Z99.9 Dependence on unspecified enabling machine and device	0.000	0.992	0.008
G81.0 Flaccid hemiplegia	0.008	0.992	0.000
Z99.2 Dependence on renal dialysis	0.000	0.992	0.008
E04.2 Non-toxic multinodular goitre	0.000	0.992	0.008
H81.2 Vestibular neuronitis	0.008	0.992	0.000
H40 Glaucoma	0.000	0.993	0.007
I10 Essential (primary) hypertension	0.007	0.993	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.993	0.007
C64 Malignant neoplasm of kidney, except renal pelvis	0.007	0.993	0.000
E04 Other non-toxic goitre	0.000	0.993	0.007
J98.4 Other disorders of lung	0.007	0.993	0.000
T40.2 Other opioids	0.007	0.993	0.000
T39.1 4-Aminophenol derivatives	0.007	0.993	0.000
T42.4 Benzodiazepines	0.006	0.994	0.000
H40.0 Glaucoma suspect	0.000	0.994	0.006
E04.0 Non-toxic diffuse goitre	0.000	0.994	0.006
T43.0 Tricyclic and tetracyclic antidepressants	0.006	0.994	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.994	0.006
H40.4 Glaucoma secondary to eye inflammation	0.000	0.994	0.006
H81 Disorders of vestibular function	0.006	0.994	0.000
H40.6 Glaucoma secondary to drugs	0.000	0.994	0.005
Z03.9 Observation for suspected disease or condition, unspecified	0.000	0.994	0.006
E80.4 Gilbert's syndrome	0.006	0.994	0.000
H81.1 Benign paroxysmal vertigo	0.005	0.995	0.000
H40.3 Glaucoma secondary to eye trauma	0.000	0.995	0.005
E04.8 Other specified non-toxic goitre	0.000	0.995	0.005
M15-M19 Arthrosis	0.000	0.995	0.005
F05 Delirium, not induced by alcohol and other psychoactive substances	0.000	0.995	0.005
H81.3 Other peripheral vertigo	0.005	0.995	0.000
H81.4 Vertigo of central origin	0.005	0.995	0.000
G35 Multiple sclerosis	0.000	0.995	0.005
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.995	0.005
H81.8 Other disorders of vestibular function	0.005	0.995	0.000
S82.2 Fracture of shaft of tibia	0.000	0.995	0.005
G82.2 Paraplegia, unspecified	0.004	0.996	0.000
H40.8 Other glaucoma	0.000	0.996	0.004
C45.9 Mesothelioma, unspecified	0.000	0.996	0.004
N70.1 Chronic salpingitis and oophoritis	0.000	0.996	0.004
M13.91 Arthritis, unspecified (Shoulder region)	0.000	0.996	0.004
H81.9 Disorder of vestibular function, unspecified	0.004	0.996	0.000
I42.0 Dilated cardiomyopathy	0.000	0.996	0.004
M15 Polyarthrosis	0.000	0.996	0.004
G82 Paraplegia and tetraplegia	0.004	0.996	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.004	0.996	0.000
F05.8 Other delirium	0.000	0.996	0.004
S82.21 Fracture of shaft of tibia (open)	0.000	0.996	0.004
H21.0 Hyphaema	0.000	0.996	0.004
C45 Mesothelioma	0.000	0.996	0.004
M13.90 Arthritis, unspecified (Multiple sites)	0.000	0.996	0.004
F05.0 Delirium not superimposed on dementia, so described	0.000	0.996	0.004
H21 Other disorders of iris and ciliary body	0.000	0.996	0.004
H21.1 Other vascular disorders of iris and ciliary body	0.000	0.996	0.004
H40.5 Glaucoma secondary to other eye disorders	0.000	0.996	0.004
M15.9 Polyarthrosis, unspecified	0.000	0.996	0.004
M13.94 Arthritis, unspecified (Hand)	0.000	0.996	0.004
C45.7 Mesothelioma of other sites	0.000	0.996	0.004
C88.0 Waldenstrom's macroglobulinaemia	0.000	0.996	0.004
H21.8 Other specified disorders of iris and ciliary body	0.000	0.996	0.004
G82.4 Spastic tetraplegia	0.004	0.996	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.002	0.996	0.002
M17.9 Gonarthrosis, unspecified	0.000	0.996	0.004
F05.1 Delirium superimposed on dementia	0.000	0.996	0.003
G82.0 Flaccid paraplegia	0.003	0.996	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
M15.99 Polyosteoarthritis, unspecified	0.000	0.997	0.003
M13.9 Arthritis, unspecified	0.000	0.997	0.003
M15.0 Primary generalised (osteo)arthrosis	0.000	0.997	0.003
H21.9 Disorder of iris and ciliary body, unspecified	0.000	0.997	0.003
M15.4 Erosive (osteo)arthrosis	0.000	0.997	0.003
E04.1 Non-toxic single thyroid nodule	0.000	0.997	0.003
K55.2 Angiodysplasia of colon	0.003	0.997	0.000
M13.93 Arthritis, unspecified (Forearm)	0.000	0.997	0.003
M15.2 Bouchard's nodes (with arthropathy)	0.000	0.997	0.003
N05.2 Diffuse membranous glomerulonephritis	0.000	0.997	0.003
H21.5 Other adhesions and disruptions of iris and ciliary body	0.000	0.997	0.003
G82.3 Flaccid tetraplegia	0.003	0.997	0.000
H40-H42 Glaucoma	0.000	0.997	0.003
M15.8 Other polyarthrosis	0.000	0.997	0.003
C45.1 Mesothelioma of peritoneum	0.000	0.997	0.003
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.997	0.003
M15.3 Secondary multiple arthrosis	0.000	0.997	0.003
H21.2 Degeneration of iris and ciliary body	0.000	0.997	0.003
M94.88 Other specified disorders of cartilage (Other)	0.003	0.997	0.000
C45.2 Mesothelioma of pericardium	0.000	0.997	0.003
C45.0 Mesothelioma of pleura	0.000	0.997	0.003
S32.00 Fracture of lumbar vertebra (closed)	0.003	0.997	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.000	0.997	0.003
I42.6 Alcoholic cardiomyopathy	0.000	0.997	0.003
C49.0 Connective and soft tissue of head, face and neck	0.000	0.997	0.003
I42.8 Other cardiomyopathies	0.000	0.997	0.003
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.997	0.003
C49.1 Connective and soft tissue of upper limb, including shoulder	0.000	0.997	0.003
N76.4 Abscess of vulva	0.003	0.997	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.997	0.003
T81.3 Disruption of operation wound, not elsewhere classified	0.000	0.997	0.003
M79.79 Fibromyalgia (Site unspecified)	0.003	0.997	0.000
C49.9 Connective and soft tissue, unspecified	0.000	0.997	0.003
M15.1 Heberden's nodes (with arthropathy)	0.000	0.997	0.003
M15.00 Primary generalized (osteo)arthrosis, Multiple sites	0.000	0.997	0.003
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.997	0.003
I42 Cardiomyopathy	0.000	0.997	0.003
G80 Infantile cerebral palsy	0.003	0.997	0.000
H21.4 Pupillary membranes	0.000	0.997	0.003
M13.97 Arthritis, unspecified (Ankle and foot)	0.000	0.997	0.003
G82.5 Tetraplegia, unspecified	0.003	0.997	0.000
H81.0 Meniere's disease	0.003	0.997	0.000
E00-E07 Disorders of thyroid gland	0.000	0.997	0.003
D86.9 Sarcoidosis, unspecified	0.003	0.997	0.000
C49.5 Connective and soft tissue of pelvis	0.000	0.997	0.003
H42 Glaucoma in diseases classified elsewhere	0.000	0.997	0.002
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.000	0.997	0.003
D25.2 Subserosal leiomyoma of uterus	0.000	0.997	0.003
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.003	0.997	0.000
G82.1 Spastic paraplegia	0.002	0.997	0.000
C49.8 Overlapping lesion of connective and soft tissue	0.000	0.997	0.002
C49.4 Connective and soft tissue of abdomen	0.000	0.997	0.002
G80.1 Spastic diplegia	0.002	0.997	0.000
K55.9 Vascular disorder of intestine, unspecified	0.003	0.997	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.000	0.997	0.002
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.997	0.002
D86 Sarcoidosis	0.002	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.998	0.002
C49.3 Connective and soft tissue of thorax	0.000	0.998	0.002
E07.8 Other specified disorders of thyroid	0.000	0.998	0.002
M13.92 Arthritis, unspecified (Upper arm)	0.000	0.998	0.002
N05 Unspecified nephritic syndrome	0.000	0.998	0.002
I42.4 Endocardial fibroelastosis	0.000	0.998	0.002
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.998	0.002
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.998	0.002
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
F41.1 Generalised anxiety disorder	0.002	0.998	0.000
D86.0 Sarcoidosis of lung	0.002	0.998	0.000
N05.1 Focal and segmental glomerular lesions	0.000	0.998	0.002
G80.0 Spastic cerebral palsy	0.002	0.998	0.000
G80.4 Ataxic cerebral palsy	0.002	0.998	0.000
G80.3 Dyskinetic cerebral palsy	0.002	0.998	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.998	0.002
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.000	0.998	0.002
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.998	0.002
N05.9 Unspecified	0.000	0.998	0.002
E07 Other disorders of thyroid	0.000	0.998	0.002
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.998	0.002
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.998	0.002
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.998	0.002
E00 Congenital iodine-deficiency syndrome	0.000	0.998	0.002
E06.5 Other chronic thyroiditis	0.000	0.998	0.002
H72.9 Perforation of tympanic membrane, unspecified	0.002	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.998	0.002
D86.8 Sarcoidosis of other and combined sites	0.002	0.998	0.000
I42.5 Other restrictive cardiomyopathy	0.000	0.998	0.002
E06 Thyroiditis	0.000	0.998	0.002
H42.8 Glaucoma in other diseases classified elsewhere	0.000	0.998	0.002
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.000	0.998	0.002
M13.8 Other specified arthritis	0.000	0.998	0.002
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.000	0.998	0.002
C46 Kaposi's sarcoma	0.000	0.998	0.002
H80-H83 Diseases of inner ear	0.002	0.998	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.998	0.002
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.000	0.998	0.002
C88 Malignant immunoproliferative diseases	0.000	0.998	0.002
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.998	0.002
F40.2 Specific (isolated) phobias	0.000	0.998	0.002
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.998	0.002
G80.2 Infantile hemiplegia	0.002	0.998	0.000
E05.5 Thyroid crisis or storm	0.000	0.998	0.002
E05.4 Thyrotoxicosis factitia	0.000	0.998	0.002
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.998	0.002
G80.8 Other infantile cerebral palsy	0.002	0.998	0.000
N21.0 Calculus in bladder	0.002	0.998	0.000
M13.86 Other specified arthritis (Lower leg)	0.000	0.998	0.002
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.998	0.002
I47.1 Supraventricular tachycardia	0.000	0.998	0.002
M94.8 Other specified disorders of cartilage	0.002	0.998	0.000
R10.0 Acute abdomen	0.002	0.998	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.000	0.998	0.002
M13 Other arthritis	0.000	0.998	0.002
E06.1 Subacute thyroiditis	0.000	0.998	0.002
M13.84 Other specified arthritis (Hand)	0.000	0.998	0.002
M13.80 Other specified arthritis (Multiple sites)	0.000	0.998	0.002
D23.4 Skin of scalp and neck	0.000	0.998	0.002
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.998	0.002
N05.6 Dense deposit disease	0.000	0.998	0.002
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.998	0.002
N05.0 Minor glomerular abnormality	0.000	0.998	0.002
M13.87 Other specified arthritis (Ankle and foot)	0.000	0.998	0.002
D86.1 Sarcoidosis of lymph nodes	0.002	0.998	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.998	0.002
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.998	0.002
R73.0 Abnormal glucose tolerance test	0.002	0.998	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.000	0.998	0.002
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.998	0.002
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.002	0.998	0.000
H31.8 Other specified disorders of choroid	0.000	0.998	0.002
N05.7 Diffuse crescentic glomerulonephritis	0.000	0.998	0.002
K55 Vascular disorders of intestine	0.002	0.998	0.000
N05.8 Other	0.000	0.998	0.002
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.998	0.002
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.998	0.002
E80 Disorders of porphyrin and bilirubin metabolism	0.002	0.998	0.000
M17 Gonarthrosis [arthrosis of knee]	0.000	0.998	0.002
H30-H36 Disorders of choroid and retina	0.000	0.998	0.002
E07.1 Dyshormogenetic goitre	0.000	0.998	0.002
E07.0 Hypersecretion of calcitonin	0.000	0.998	0.002
H40.1 Primary open-angle glaucoma	0.000	0.998	0.002
Z74.8 Other problems related to care-provider dependency	0.000	0.998	0.002
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.998	0.002
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.998	0.002
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.998	0.002
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.998	0.002
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.998	0.002
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.998	0.002
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.998	0.002
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.998	0.002
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.998	0.002
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.998	0.002
E27.9 Disorder of adrenal gland, unspecified	0.000	0.998	0.002
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.002	0.998	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.002	0.998	0.000
H80 Otosclerosis	0.002	0.998	0.000
M13.89 Other specified arthritis (Site unspecified)	0.000	0.998	0.002
M13.88 Other specified arthritis (Other)	0.000	0.998	0.002
M13.85 Other specified arthritis (Pelvic region and thigh)	0.000	0.998	0.002
M13.82 Other specified arthritis (Upper arm)	0.000	0.998	0.002
M13.81 Other specified arthritis (Shoulder region)	0.000	0.998	0.002
C46.9 Kaposi's sarcoma, unspecified	0.000	0.998	0.002
C46.8 Kaposi's sarcoma of multiple organs	0.000	0.998	0.002
C46.7 Kaposi's sarcoma of other sites	0.000	0.998	0.002
C46.3 Kaposi's sarcoma of lymph nodes	0.000	0.998	0.002
C46.2 Kaposi's sarcoma of palate	0.000	0.998	0.002
C46.1 Kaposi's sarcoma of soft tissue	0.000	0.998	0.002
C46.0 Kaposi's sarcoma of skin	0.000	0.998	0.002
C47.9 Peripheral nerves and autonomic nervous system, unspecified	0.000	0.998	0.002
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system	0.000	0.998	0.002
C47.6 Peripheral nerves of trunk, unspecified	0.000	0.998	0.002
C47.5 Peripheral nerves of pelvis	0.000	0.998	0.002
C47.4 Peripheral nerves of abdomen	0.000	0.998	0.002
C47.3 Peripheral nerves of thorax	0.000	0.998	0.002
C47.2 Peripheral nerves of lower limb, including hip	0.000	0.998	0.002
C47.1 Peripheral nerves of upper limb, including shoulder	0.000	0.998	0.002
C47.0 Peripheral nerves of head, face and neck	0.000	0.998	0.002
E06.4 Drug-induced thyroiditis	0.000	0.998	0.002
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.998	0.002
E06.0 Acute thyroiditis	0.000	0.998	0.002
N41.1 Chronic prostatitis	0.000	0.998	0.002
H82 Vertiginous syndromes in diseases classified elsewhere	0.002	0.998	0.000
M45 Ankylosing spondylitis	0.000	0.998	0.002
M05.19 Rheumatoid lung disease (Site unspecified)	0.000	0.998	0.002
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.998	0.002
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.998	0.002
C88.9 Malignant immunoproliferative disease, unspecified	0.000	0.998	0.002
C88.7 Other malignant immunoproliferative diseases	0.000	0.998	0.002
C88.3 Immunoproliferative small intestinal disease	0.000	0.998	0.002
C88.2 Gamma heavy chain disease	0.000	0.998	0.002
C88.1 Alpha heavy chain disease	0.000	0.998	0.002
E05.8 Other thyrotoxicosis	0.000	0.998	0.002
K55.8 Other vascular disorders of intestine	0.002	0.998	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.002	0.998	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.998	0.002
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.998	0.002
E06.9 Thyroiditis, unspecified	0.000	0.998	0.002
M94.81 Other specified disorders of cartilage (Shoulder region)	0.002	0.998	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.002	0.998	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.002	0.998	0.000
N93.0 Postcoital and contact bleeding	0.002	0.998	0.000
H31 Other disorders of choroid	0.000	0.998	0.002
M94.84 Other specified disorders of cartilage (Hand)	0.002	0.998	0.000
M94.83 Other specified disorders of cartilage (Forearm)	0.002	0.998	0.000
M94.82 Other specified disorders of cartilage (Upper arm)	0.002	0.998	0.000
M94.80 Other specified disorders of cartilage (Multiple sites)	0.002	0.998	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.000	0.998	0.002
M13.1 Monoarthritis, not elsewhere classified	0.000	0.998	0.002
M89.87 Other specified disorders of bone (Ankle and foot)	0.002	0.998	0.000
M05.1 Rheumatoid lung disease	0.000	0.998	0.002
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.998	0.002
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.998	0.002
E80.6 Other disorders of bilirubin metabolism	0.002	0.998	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.998	0.002
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.002	0.998	0.000
H80.8 Other otosclerosis	0.002	0.998	0.000
M13.83 Other specified arthritis (Forearm)	0.000	0.998	0.001
H31.3 Choroidal haemorrhage and rupture	0.000	0.998	0.002
M05.2 Rheumatoid vasculitis	0.000	0.998	0.002
Z74.0 Reduced mobility	0.000	0.998	0.002
M05.29 Rheumatoid vasculitis (Site unspecified)	0.000	0.998	0.001
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.998	0.002
G80.9 Infantile cerebral palsy, unspecified	0.001	0.998	0.000
R14 Flatulence and related conditions	0.002	0.998	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.998	0.002
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.998	0.001
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.998	0.001
E80.5 Crigler-Najjar syndrome	0.001	0.998	0.000
E80.3 Defects of catalase and peroxydase	0.001	0.998	0.000
E80.0 Hereditary erythropoietic porphyria	0.001	0.998	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.000	0.998	0.001
M18 Arthrosis of first carpometacarpal joint	0.000	0.998	0.002
S52.60 Fracture of lower end of both ulna and radius (closed)	0.002	0.998	0.000
E80.2 Other porphyria	0.001	0.998	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.002	0.998	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.000	0.998	0.001
H80.2 Cochlear otosclerosis	0.001	0.998	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations