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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12423712
log Bayes Factor = 0.0543282
Chromosome 12   position 125,033,933  (GRCh37) Explore rs12423712 on Ensembl!
Variant rs12423712 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M54.96 Dorsalgia, unspecified (Lumbar region)
0.082 0.918 0.000
M54.9 Dorsalgia, unspecified
0.079 0.921 0.000
R53 Malaise and fatigue
0.072 0.928 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.067 0.933 0.000
M54 Dorsalgia
0.066 0.934 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.065 0.935 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.063 0.937 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.062 0.937 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.057 0.943 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.057 0.943 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.057 0.943 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.057 0.943 0.000
M54.5 Low back pain
0.056 0.944 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.053 0.947 0.000
M54.4 Lumbago with sciatica
0.052 0.948 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.051 0.949 0.000
M54.3 Sciatica
0.050 0.950 0.000
M54.50 Low back pain (Multiple sites in spine)
0.050 0.950 0.000
M54.1 Radiculopathy
0.048 0.952 0.000
M54.8 Other dorsalgia
0.047 0.953 0.000
M54.0 Panniculitis affecting regions of neck and back
0.047 0.953 0.000
M54.2 Cervicalgia
0.046 0.954 0.000
M54.39 Sciatica (Site unspecified)
0.045 0.955 0.000
M54.6 Pain in thoracic spine
0.044 0.956 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.043 0.957 0.000
M54.59 Low back pain (Site unspecified)
0.043 0.957 0.000
M50-M54 Other dorsopathies
0.041 0.958 0.001
M54.54 Low back pain-Thoracic
0.041 0.959 0.000
M54.53 Low back pain-Cervicothoracic
0.041 0.959 0.000
M54.52 Low back pain-Cervical
0.041 0.959 0.000
M54.51 Low back pain-Occipit-atl-axl
0.041 0.959 0.000
M54.22 Cervicalgia (Cervical region)
0.039 0.961 0.000
M54.57 Low back pain (Lumbosacral region)
0.039 0.961 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.038 0.962 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.038 0.962 0.000
M54.55 Low back pain (Thoracolumbar region)
0.038 0.962 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.037 0.963 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.037 0.963 0.000
M54.44 Lumbago with sciatica-Thoracic
0.037 0.963 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.037 0.963 0.000
M54.42 Lumbago with sciatica-Cervical
0.037 0.963 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.037 0.963 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.037 0.963 0.000
M54.16 Radiculopathy (Lumbar region)
0.037 0.963 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.036 0.964 0.000
M54.35 Sciatica (Thoracolumbar region)
0.036 0.964 0.000
M54.34 Sciatica-Thoracic
0.036 0.964 0.000
M54.33 Sciatica-Cervicothoracic
0.036 0.964 0.000
M54.32 Sciatica-Cervical
0.036 0.964 0.000
M54.31 Sciatica-Occipit-atl-axl
0.036 0.964 0.000
M54.30 Sciatica (Multiple sites in spine)
0.036 0.964 0.000
M53 Other dorsopathies, not elsewhere classified
0.035 0.965 0.000
M54.19 Radiculopathy (Site unspecified)
0.035 0.965 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.035 0.965 0.000
M54.14 Radiculopathy (Thoracic region)
0.035 0.965 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.035 0.965 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.035 0.965 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.035 0.965 0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)
0.034 0.966 0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)
0.034 0.966 0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)
0.034 0.966 0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)
0.034 0.966 0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)
0.034 0.966 0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)
0.034 0.966 0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)
0.034 0.966 0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)
0.034 0.966 0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)
0.034 0.966 0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)
0.034 0.966 0.000
M54.89 Other dorsalgia (Site unspecified)
0.034 0.966 0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)
0.034 0.966 0.000
M54.87 Other dorsalgia (Lumbosacral region)
0.034 0.966 0.000
M54.86 Other dorsalgia (Lumbar region)
0.034 0.966 0.000
M54.85 Other dorsalgia (Thoracolumbar region)
0.034 0.966 0.000
M54.84 Other dorsalgia (Thoracic region)
0.034 0.966 0.000
M54.83 Other dorsalgia (Cervicothoracic region)
0.034 0.966 0.000
M54.82 Other dorsalgia (Cervical region)
0.034 0.966 0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)
0.034 0.966 0.000
M54.80 Other dorsalgia (Multiple sites in spine)
0.034 0.966 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.034 0.966 0.000
M50 Cervical disk disorders
0.034 0.966 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.033 0.967 0.000
M54.36 Sciatica (Lumbar region)
0.033 0.967 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.033 0.967 0.000
M54.27 Cervicalgia-Lumbosacral
0.033 0.967 0.000
M54.26 Cervicalgia-Lumbar
0.033 0.967 0.000
M54.25 Cervicalgia-Thoracolumbar
0.033 0.967 0.000
M54.24 Cervicalgia-Thoracic
0.033 0.967 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.033 0.967 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.033 0.967 0.000
M54.20 Cervicalgia-Mult site
0.033 0.967 0.000
M54.69 Pain in thoracic spine-Site unspe
0.031 0.968 0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ
0.031 0.968 0.000
M54.67 Pain in thoracic spine-Lumbosacral
0.031 0.968 0.000
M54.66 Pain in thoracic spine-Lumbar
0.031 0.968 0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)
0.031 0.968 0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)
0.031 0.968 0.000
M54.62 Pain in thoracic spine-Cervical
0.031 0.968 0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl
0.031 0.968 0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)
0.031 0.968 0.000
M50.3 Other cervical disk degeneration
0.031 0.969 0.000
M51.2 Other specified intervertebral disk displacement
0.000 0.969 0.031
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.031 0.969 0.000
M54.12 Radiculopathy (Cervical region)
0.029 0.971 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.028 0.972 0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s
0.028 0.972 0.000
M54.37 Sciatica (Lumbosacral region)
0.026 0.974 0.000
M50.9 Cervical disk disorder, unspecified
0.026 0.974 0.000
M53.9 Dorsopathy, unspecified
0.025 0.974 0.000
M53.8 Other specified dorsopathies
0.025 0.974 0.000
M53.2 Spinal instabilities
0.025 0.974 0.000
M53.1 Cervicobrachial syndrome
0.025 0.974 0.000
M53.0 Cervicocranial syndrome
0.025 0.974 0.000
M50.8 Other cervical disk disorders
0.024 0.975 0.000
M50.1 Cervical disk disorder with radiculopathy
0.023 0.976 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.023 0.977 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.023 0.977 0.000
M51 Other intervertebral disk disorders
0.010 0.977 0.013
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns
0.022 0.978 0.000
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac
0.022 0.978 0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar
0.022 0.978 0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol
0.022 0.978 0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic
0.022 0.978 0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot
0.022 0.978 0.000
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical
0.022 0.978 0.000
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-
0.022 0.978 0.000
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit
0.022 0.978 0.000
M80-M85 Disorders of bone density and structure
0.022 0.978 0.000
M06 Other rheumatoid arthritis
0.021 0.979 0.000
M86-M90 Other osteopathies
0.021 0.979 0.000
M05-M14 Inflammatory polyarthropathies
0.021 0.979 0.000
M06.9 Rheumatoid arthritis, unspecified
0.021 0.979 0.000
M24 Other specific joint derangements
0.021 0.979 0.000
M21.3 Wrist or foot drop (acquired)
0.021 0.979 0.000
M85 Other disorders of bone density and structure
0.021 0.979 0.000
M50.2 Other cervical disk displacement
0.021 0.979 0.000
M00-M03 Infectious arthropathies
0.020 0.980 0.000
M21 Other acquired deformities of limbs
0.020 0.980 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.019 0.981 0.000
M54.29 Cervicalgia-Site unspe
0.019 0.981 0.001
M24.0 Loose body in joint
0.019 0.981 0.000
M50.0 Cervical disk disorder with myelopathy
0.019 0.981 0.000
M24.5 Contracture of joint
0.019 0.981 0.000
M20-M25 Other joint disorders
0.019 0.981 0.000
M88 Paget's disease of bone [osteitis deformans]
0.019 0.981 0.000
M24.2 Disorder of ligament
0.019 0.981 0.000
M54.56 Low back pain (Lumbar region)
0.019 0.981 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.019 0.981 0.000
M85.0 Fibrous dysplasia (monostotic)
0.019 0.981 0.000
M53.09 Cervicocranial syndrome-Site unspe
0.018 0.981 0.000
M53.08 Cervicocranial syndrome-Sacral/sacrococ
0.018 0.981 0.000
M53.07 Cervicocranial syndrome-Lumbosacral
0.018 0.981 0.000
M53.06 Cervicocranial syndrome-Lumbar
0.018 0.981 0.000
M53.05 Cervicocranial syndrome-Thoracolumbar
0.018 0.981 0.000
M53.04 Cervicocranial syndrome-Thoracic
0.018 0.981 0.000
M53.03 Cervicocranial syndrome (Cervicothoracic region)
0.018 0.981 0.000
M53.02 Cervicocranial syndrome (Cervical region)
0.018 0.981 0.000
M53.01 Cervicocranial syndrome (Occipito-atlanto-axial region)
0.018 0.981 0.000
M53.00 Cervicocranial syndrome (Multiple sites in spine)
0.018 0.981 0.000
M53.19 Cervicobrachial syndrome-Site unspe
0.018 0.981 0.000
M53.18 Cervicobrachial syndrome-Sacral/sacrococ
0.018 0.981 0.000
M53.17 Cervicobrachial syndrome-Lumbosacral
0.018 0.981 0.000
M53.16 Cervicobrachial syndrome-Lumbar
0.018 0.981 0.000
M53.15 Cervicobrachial syndrome-Thoracolumbar
0.018 0.981 0.000
M53.14 Cervicobrachial syndrome-Thoracic
0.018 0.981 0.000
M53.13 Cervicobrachial syndrome (Cervicothoracic region)
0.018 0.981 0.000
M53.12 Cervicobrachial syndrome (Cervical region)
0.018 0.981 0.000
M53.11 Cervicobrachial syndrome (Occipito-atlanto-axial region)
0.018 0.981 0.000
M53.10 Cervicobrachial syndrome (Multiple sites in spine)
0.018 0.981 0.000
M53.29 Spinal instabilities (Site unspecified)
0.018 0.981 0.000
M53.28 Spinal instabilities (Sacral and sacrococcygeal region)
0.018 0.981 0.000
M53.27 Spinal instabilities (Lumbosacral region)
0.018 0.981 0.000
M53.26 Spinal instabilities (Lumbar region)
0.018 0.981 0.000
M53.25 Spinal instabilities (Thoracolumbar region)
0.018 0.981 0.000
M53.24 Spinal instabilities (Thoracic region)
0.018 0.981 0.000
M53.23 Spinal instabilities (Cervicothoracic region)
0.018 0.981 0.000
M53.22 Spinal instabilities (Cervical region)
0.018 0.981 0.000
M53.21 Spinal instabilities (Occipito-atlanto-axial region)
0.018 0.981 0.000
M53.20 Spinal instabilities (Multiple sites in spine)
0.018 0.981 0.000
M53.89 Other specified dorsopathies (Site unspecified)
0.018 0.981 0.000
M53.88 Other specified dorsopathies (Sacral and sacrococcygeal region)
0.018 0.981 0.000
M53.87 Other specified dorsopathies (Lumbosacral region)
0.018 0.981 0.000
M53.86 Other specified dorsopathies (Lumbar region)
0.018 0.981 0.000
M53.85 Other specified dorsopathies (Thoracolumbar region)
0.018 0.981 0.000
M53.84 Other specified dorsopathies (Thoracic region)
0.018 0.981 0.000
M53.83 Other specified dorsopathies (Cervicothoracic region)
0.018 0.981 0.000
M53.82 Other specified dorsopathies (Cervical region)
0.018 0.981 0.000
M53.81 Other specified dorsopathies (Occipito-atlanto-axial region)
0.018 0.981 0.000
M53.80 Other specified dorsopathies (Multiple sites in spine)
0.018 0.981 0.000
M53.99 Dorsopathy, unspecified (Site unspecified)
0.018 0.981 0.000
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)
0.018 0.981 0.000
M53.97 Dorsopathy, unspecified (Lumbosacral region)
0.018 0.981 0.000
M53.96 Dorsopathy, unspecified (Lumbar region)
0.018 0.981 0.000
M53.95 Dorsopathy, unspecified (Thoracolumbar region)
0.018 0.981 0.000
M53.94 Dorsopathy, unspecified (Thoracic region)
0.018 0.981 0.000
M53.93 Dorsopathy, unspecified (Cervicothoracic region)
0.018 0.981 0.000
M53.92 Dorsopathy, unspecified (Cervical region)
0.018 0.981 0.000
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)
0.018 0.981 0.000
M53.90 Dorsopathy, unspecified (Multiple sites in spine)
0.018 0.981 0.000
M84 Disorders of continuity of bone
0.019 0.981 0.000
M00 Pyogenic arthritis
0.018 0.982 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.018 0.982 0.000
M89 Other disorders of bone
0.018 0.982 0.000
M14 Arthropathies in other diseases classified elsewhere
0.018 0.982 0.000
M80 Osteoporosis with pathological fracture
0.018 0.982 0.000
M24.54 Contracture of joint (Hand)
0.018 0.982 0.000
M86 Osteomyelitis
0.018 0.982 0.000
M88.9 Paget's disease of bone, unspecified
0.017 0.983 0.000
M24.6 Ankylosis of joint
0.017 0.983 0.000
M24.24 Disorder of ligament (Hand)
0.017 0.983 0.000
M00.9 Pyogenic arthritis, unspecified
0.017 0.983 0.000
M06.3 Rheumatoid nodule
0.017 0.983 0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)
0.017 0.983 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.017 0.983 0.000
M06.4 Inflammatory polyarthropathy
0.017 0.983 0.000
M85.8 Other specified disorders of bone density and structure
0.017 0.983 0.000
M82 Osteoporosis in diseases classified elsewhere
0.017 0.983 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.017 0.983 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.017 0.983 0.000
M84.0 Malunion of fracture
0.017 0.983 0.000
M85.6 Other cyst of bone
0.017 0.983 0.000
M40-M43 Deforming dorsopathies
0.017 0.983 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.017 0.983 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.017 0.983 0.000
M24.01 Loose body in joint (Shoulder region)
0.017 0.983 0.000
M51.3 Other specified intervertebral disk degeneration
0.007 0.983 0.009
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.007 0.983 0.009
M51.4 Schmorl's nodes
0.007 0.983 0.009
M60-M63 Disorders of muscles
0.016 0.984 0.000
M83 Adult osteomalacia
0.016 0.984 0.000
M24.02 Loose body in joint (Upper arm)
0.016 0.984 0.000
M84.03 Malunion of fracture (Forearm)
0.016 0.984 0.000
M14.6 Neuropathic arthropathy
0.016 0.984 0.000
M51.8 Other specified intervertebral disk disorders
0.005 0.984 0.010
M06.8 Other specified rheumatoid arthritis
0.015 0.984 0.000
M06.2 Rheumatoid bursitis
0.015 0.984 0.000
M06.1 Adult-onset Still's disease
0.015 0.984 0.000
M12 Other specific arthropathies
0.015 0.984 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.015 0.984 0.000
M08 Juvenile arthritis
0.015 0.984 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.015 0.984 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.015 0.984 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.015 0.984 0.000
M24.9 Joint derangement, unspecified
0.015 0.984 0.000
M24.7 Protrusio acetabuli
0.015 0.984 0.000
M51.9 Intervertebral disk disorder, unspecified
0.007 0.984 0.008
M88.90 Paget's disease of bone, unspecified (Multiple sites)
0.015 0.985 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.015 0.985 0.000
M21.39 Wrist or foot drop (acquired)-Site unspec
0.015 0.985 0.000
M21.38 Wrist or foot drop (acquired)-Other
0.015 0.985 0.000
M21.36 Wrist or foot drop (acquired)-Lower leg
0.015 0.985 0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh
0.015 0.985 0.000
M21.34 Wrist or foot drop (acquired) (Hand)
0.015 0.985 0.000
M21.33 Wrist or foot drop (acquired) (Forearm)
0.015 0.985 0.000
M21.32 Wrist or foot drop (acquired)-Upper arm
0.015 0.985 0.000
M21.31 Wrist or foot drop (acquired)-Shldr region
0.015 0.985 0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)
0.015 0.985 0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)
0.015 0.985 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.015 0.985 0.000
M85.9 Disorder of bone density and structure, unspecified
0.015 0.985 0.000
M85.5 Aneurysmal bone cyst
0.015 0.985 0.000
M85.4 Solitary bone cyst
0.015 0.985 0.000
M85.3 Osteitis condensans
0.015 0.985 0.000
M85.2 Hyperostosis of skull
0.015 0.985 0.000
M85.1 Skeletal fluorosis
0.015 0.985 0.000
M87 Osteonecrosis
0.015 0.985 0.000
M11 Other crystal arthropathies
0.015 0.985 0.000
M81 Osteoporosis without pathological fracture
0.015 0.985 0.000
M86.9 Osteomyelitis, unspecified
0.015 0.985 0.000
M24.07 Loose body in joint (Ankle and foot)
0.015 0.985 0.000
M33 Dermatopolymyositis
0.015 0.985 0.000
M30 Polyarteritis nodosa and related conditions
0.015 0.985 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.015 0.985 0.000
M02 Reactive arthropathies
0.015 0.985 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.015 0.985 0.000
M07 Psoriatic and enteropathic arthropathies
0.015 0.985 0.000
M21.4 Flat foot [pes planus] (acquired)
0.015 0.985 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.006 0.985 0.009
M05 Seropositive rheumatoid arthritis
0.015 0.985 0.000
M24.67 Ankylosis of joint (Ankle and foot)
0.015 0.985 0.000
M21.0 Valgus deformity, not elsewhere classified
0.015 0.985 0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)
0.015 0.985 0.000
M89.8 Other specified disorders of bone
0.015 0.985 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.014 0.985 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.014 0.985 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.014 0.986 0.000
M21.9 Acquired deformity of limb, unspecified
0.014 0.986 0.000
M21.8 Other specified acquired deformities of limbs
0.014 0.986 0.000
M21.7 Unequal limb length (acquired)
0.014 0.986 0.000
M24.51 Contracture of joint (Shoulder region)
0.014 0.986 0.000
M10 Gout
0.014 0.986 0.000
M06.34 Rheumatoid nodule (Hand)
0.014 0.986 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.014 0.986 0.000
M24.26 Disorder of ligament (Lower leg)
0.014 0.986 0.000
M24.09 Loose body in joint (Site unspecified)
0.014 0.986 0.000
M24.08 Loose body in joint (Other)
0.014 0.986 0.000
M24.06 Loose body in joint-Lower leg
0.014 0.986 0.000
M24.05 Loose body in joint (Pelvic region and thigh)
0.014 0.986 0.000
M24.04 Loose body in joint (Hand)
0.014 0.986 0.000
M24.03 Loose body in joint (Forearm)
0.014 0.986 0.000
M24.00 Loose body in joint (Multiple sites)
0.014 0.986 0.000
M89.9 Disorder of bone, unspecified
0.014 0.986 0.000
M24.59 Contracture of joint (Site unspecified)
0.014 0.986 0.000
M24.58 Contracture of joint (Other)
0.014 0.986 0.000
M24.57 Contracture of joint (Ankle and foot)
0.014 0.986 0.000
M24.56 Contracture of joint (Lower leg)
0.014 0.986 0.000
M24.55 Contracture of joint (Pelvic region and thigh)
0.014 0.986 0.000
M24.53 Contracture of joint (Forearm)
0.014 0.986 0.000
M24.52 Contracture of joint (Upper arm)
0.014 0.986 0.000
M24.50 Contracture of joint (Multiple sites)
0.014 0.986 0.000
M21.2 Flexion deformity
0.014 0.986 0.000
M00.94 Pyogenic arthritis, unspecified (Hand)
0.014 0.986 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.014 0.986 0.000
M32 Systemic lupus erythematosus
0.014 0.986 0.000
M06.0 Seronegative rheumatoid arthritis
0.014 0.986 0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)
0.014 0.986 0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)
0.014 0.986 0.000
M88.8 Paget's disease of other bones
0.014 0.986 0.000
M88.0 Paget's disease of skull
0.014 0.986 0.000
M24.29 Disorder of ligament (Site unspecified)
0.014 0.986 0.000
M24.28 Disorder of ligament (Other)
0.014 0.986 0.000
M24.25 Disorder of ligament (Pelvic region and thigh)
0.014 0.986 0.000
M24.22 Disorder of ligament (Upper arm)
0.014 0.986 0.000
M24.21 Disorder of ligament (Shoulder region)
0.014 0.986 0.000
M24.20 Disorder of ligament (Multiple sites)
0.014 0.986 0.000
M89.5 Osteolysis
0.014 0.986 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.014 0.986 0.000
M31 Other necrotising vasculopathies
0.014 0.986 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.014 0.986 0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)
0.014 0.986 0.000
M85.08 Fibrous dysplasia (monostotic) (Other)
0.014 0.986 0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)
0.014 0.986 0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)
0.014 0.986 0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)
0.014 0.986 0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)
0.014 0.986 0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)
0.014 0.986 0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)
0.014 0.986 0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)
0.014 0.986 0.000
M21.6 Other acquired deformities of ankle and foot
0.014 0.986 0.000
M21.1 Varus deformity, not elsewhere classified
0.014 0.986 0.000
M89.0 Algoneurodystrophy
0.014 0.986 0.000
M84.9 Disorder of continuity of bone, unspecified
0.013 0.986 0.000
M84.8 Other disorders of continuity of bone
0.013 0.986 0.000
M84.3 Stress fracture, not elsewhere classified
0.013 0.986 0.000
M84.2 Delayed union of fracture
0.013 0.986 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.013 0.986 0.000
M41 Scoliosis
0.013 0.986 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.013 0.986 0.000
M90 Osteopathies in diseases classified elsewhere
0.013 0.986 0.000
M00.8 Arthritis and polyarthritis due to other specified bacterial agents
0.013 0.987 0.000
M00.2 Other streptococcal arthritis and polyarthritis
0.013 0.987 0.000
M00.1 Pneumococcal arthritis and polyarthritis
0.013 0.987 0.000
M00.0 Staphylococcal arthritis and polyarthritis
0.013 0.987 0.000
M82.1 Osteoporosis in endocrine disorders
0.013 0.987 0.000
M24.23 Disorder of ligament (Forearm)
0.013 0.987 0.000
M85.67 Other cyst of bone (Ankle and foot)
0.013 0.987 0.000
M89.6 Osteopathy after poliomyelitis
0.013 0.987 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.013 0.987 0.000
M89.3 Hypertrophy of bone
0.013 0.987 0.000
M89.2 Other disorders of bone development and growth
0.013 0.987 0.000
M89.1 Epiphyseal arrest
0.013 0.987 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.013 0.987 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.013 0.987 0.000
M14.4 Arthropathy in amyloidosis
0.013 0.987 0.000
M14.3 Lipoid dermatoarthritis
0.013 0.987 0.000
M14.2 Diabetic arthropathy
0.013 0.987 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.013 0.987 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.013 0.987 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.013 0.987 0.000
M80.8 Other osteoporosis with pathological fracture
0.013 0.987 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.013 0.987 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.013 0.987 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.013 0.987 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.013 0.987 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.013 0.987 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.013 0.987 0.000
M84.4 Pathological fracture, not elsewhere classified
0.013 0.987 0.000
M86.8 Other osteomyelitis
0.013 0.987 0.000
M86.6 Other chronic osteomyelitis
0.013 0.987 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.013 0.987 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.013 0.987 0.000
M86.3 Chronic multifocal osteomyelitis
0.013 0.987 0.000
M86.2 Subacute osteomyelitis
0.013 0.987 0.000
M86.1 Other acute osteomyelitis
0.013 0.987 0.000
M86.0 Acute haematogenous osteomyelitis
0.013 0.987 0.000
M85.65 Other cyst of bone (Pelvic region and thigh)
0.013 0.987 0.000
M35 Other systemic involvement of connective tissue
0.013 0.987 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.013 0.987 0.000
M88.98 Paget's disease of bone, unspecified (Other)
0.013 0.987 0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)
0.013 0.987 0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)
0.013 0.987 0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)
0.013 0.987 0.000
M88.94 Paget's disease of bone, unspecified (Hand)
0.013 0.987 0.000
M88.93 Paget's disease of bone, unspecified (Forearm)
0.013 0.987 0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)
0.013 0.987 0.000
M88.91 Paget's disease of bone, unspecified (Shoulder region)
0.013 0.987 0.000
M24.69 Ankylosis of joint (Site unspecified)
0.013 0.987 0.000
M24.68 Ankylosis of joint (Other)
0.013 0.987 0.000
M24.66 Ankylosis of joint (Lower leg)
0.013 0.987 0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)
0.013 0.987 0.000
M24.64 Ankylosis of joint (Hand)
0.013 0.987 0.000
M24.63 Ankylosis of joint (Forearm)
0.013 0.987 0.000
M24.62 Ankylosis of joint (Upper arm)
0.013 0.987 0.000
M24.61 Ankylosis of joint (Shoulder region)
0.013 0.987 0.000
M24.60 Ankylosis of joint (Multiple sites)
0.013 0.987 0.000
M60 Myositis
0.013 0.987 0.000
M91-M94 Chondropathies
0.012 0.987 0.000
M00.99 Pyogenic arthritis, unspecified (Site unspecified)
0.012 0.987 0.000
M00.98 Pyogenic arthritis, unspecified (Other)
0.012 0.987 0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)
0.012 0.987 0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)
0.012 0.987 0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)
0.012 0.987 0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)
0.012 0.987 0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)
0.012 0.987 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.012 0.987 0.000
M06.38 Rheumatoid nodule (Other)
0.012 0.987 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.012 0.987 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.012 0.987 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.012 0.987 0.000
M06.33 Rheumatoid nodule (Forearm)
0.012 0.987 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.012 0.987 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.012 0.987 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.012 0.987 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.012 0.987 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.012 0.987 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.012 0.987 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.012 0.987 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.012 0.987 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.012 0.987 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.012 0.987 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.012 0.987 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.012 0.987 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.012 0.987 0.000
M85.88 Other specified disorders of bone density and structure (Other)
0.012 0.987 0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)
0.012 0.987 0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)
0.012 0.987 0.000
M85.84 Other specified disorders of bone density and structure (Hand)
0.012 0.987 0.000
M85.83 Other specified disorders of bone density and structure (Forearm)
0.012 0.987 0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)
0.012 0.987 0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)
0.012 0.987 0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)
0.012 0.987 0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)
0.012 0.987 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.012 0.987 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.012 0.987 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.012 0.987 0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)
0.012 0.987 0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)
0.012 0.987 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.012 0.987 0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)
0.012 0.987 0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)
0.012 0.987 0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)
0.012 0.987 0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)
0.012 0.987 0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)
0.012 0.988 0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)
0.012 0.988 0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)
0.012 0.988 0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)
0.012 0.988 0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)
0.012 0.988 0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)
0.012 0.988 0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)
0.012 0.988 0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)
0.012 0.988 0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)
0.012 0.988 0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)
0.012 0.988 0.000
M84.09 Malunion of fracture (Site unspecified)
0.012 0.988 0.000
M84.08 Malunion of fracture (Other)
0.012 0.988 0.000
M84.07 Malunion of fracture (Ankle and foot)
0.012 0.988 0.000
M84.06 Malunion of fracture (Lower leg)
0.012 0.988 0.000
M84.05 Malunion of fracture (Pelvic region and thigh)
0.012 0.988 0.000
M84.04 Malunion of fracture (Hand)
0.012 0.988 0.000
M84.02 Malunion of fracture (Upper arm)
0.012 0.988 0.000
M84.01 Malunion of fracture (Shoulder region)
0.012 0.988 0.000
M84.00 Malunion of fracture (Multiple sites)
0.012 0.988 0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)
0.012 0.988 0.000
M85.69 Other cyst of bone (Site unspecified)
0.012 0.988 0.000
M85.68 Other cyst of bone (Other)
0.012 0.988 0.000
M85.66 Other cyst of bone (Lower leg)
0.012 0.988 0.000
M85.64 Other cyst of bone (Hand)
0.012 0.988 0.000
M85.63 Other cyst of bone (Forearm)
0.012 0.988 0.000
M85.62 Other cyst of bone (Upper arm)
0.012 0.988 0.000
M85.61 Other cyst of bone (Shoulder region)
0.012 0.988 0.000
M85.60 Other cyst of bone (Multiple sites)
0.012 0.988 0.000
M42 Spinal osteochondrosis
0.012 0.988 0.000
M40 Kyphosis and lordosis
0.012 0.988 0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)
0.012 0.988 0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)
0.012 0.988 0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)
0.012 0.988 0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)
0.012 0.988 0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)
0.012 0.988 0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)
0.012 0.988 0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)
0.012 0.988 0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)
0.012 0.988 0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)
0.012 0.988 0.000
M30.0 Polyarteritis nodosa
0.012 0.988 0.000
M13 Other arthritis
0.012 0.988 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.012 0.988 0.000
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified
0.005 0.988 0.007
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region
0.005 0.988 0.007
M51.37 Other intervertebral disc degeneration, lumbosacral region
0.005 0.988 0.007
M63 Disorders of muscle in diseases classified elsewhere
0.012 0.988 0.000
M61 Calcification and ossification of muscle
0.012 0.988 0.000
M83.9 Adult osteomalacia, unspecified
0.012 0.988 0.000
M83.8 Other adult osteomalacia
0.012 0.988 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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