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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12436663
log Bayes Factor = 0.0452172
Chromosome 14   position 35,639,120  (GRCh37) Explore rs12436663 on Ensembl!
Variant rs12436663 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C67 Malignant neoplasm of bladder
0.000 0.948 0.052
C67.4 Posterior wall of bladder
0.000 0.949 0.051
C64-C68 Malignant neoplasms of urinary tract
0.000 0.949 0.051
C64 Malignant neoplasm of kidney, except renal pelvis
0.000 0.950 0.050
C67.9 Bladder, unspecified
0.000 0.950 0.050
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.000 0.951 0.049
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.000 0.953 0.047
C65 Malignant neoplasm of renal pelvis
0.000 0.954 0.046
C66 Malignant neoplasm of ureter
0.000 0.957 0.043
C67.8 Overlapping lesion of bladder
0.000 0.958 0.042
T84.0 Mechanical complication of internal joint prosthesis
0.000 0.959 0.041
O02.1 Missed abortion
0.000 0.959 0.041
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.000 0.960 0.040
C67.0 Trigone of bladder
0.000 0.961 0.039
C67.1 Dome of bladder
0.000 0.962 0.037
C67.7 Urachus
0.000 0.963 0.037
C68 Malignant neoplasm of other and unspecified urinary organs
0.000 0.963 0.037
C67.2 Lateral wall of bladder
0.000 0.964 0.036
T84.2 Mechanical complication of internal fixation device of other bones
0.000 0.965 0.035
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.000 0.967 0.033
C67.6 Ureteric orifice
0.000 0.968 0.032
Q61.3 Polycystic kidney, unspecified
0.000 0.968 0.032
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.000 0.969 0.031
C67.3 Anterior wall of bladder
0.000 0.973 0.027
T84.1 Mechanical complication of internal fixation device of bones of limb
0.000 0.973 0.027
C68.9 Urinary organ, unspecified
0.000 0.973 0.026
C68.8 Overlapping lesion of urinary organs
0.000 0.973 0.026
C68.1 Paraurethral glands
0.000 0.973 0.026
C68.0 Urethra
0.000 0.973 0.026
Q61 Cystic kidney disease
0.000 0.974 0.026
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.000 0.974 0.026
T84.3 Mechanical complication of other bone devices, implants and grafts
0.000 0.974 0.026
C67.5 Bladder neck
0.000 0.974 0.026
E04.9 Non-toxic goitre, unspecified
0.023 0.977 0.000
O02 Other abnormal products of conception
0.000 0.977 0.023
Q61.2 Polycystic kidney, adult type
0.000 0.978 0.022
Q61.0 Congenital single renal cyst
0.000 0.979 0.021
Q61.5 Medullary cystic kidney
0.000 0.980 0.020
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.000 0.980 0.020
Q61.9 Cystic kidney disease, unspecified
0.000 0.981 0.019
Q61.8 Other cystic kidney diseases
0.000 0.981 0.019
Q61.4 Renal dysplasia
0.000 0.981 0.019
Q61.1 Polycystic kidney, infantile type
0.000 0.981 0.019
E04 Other non-toxic goitre
0.018 0.982 0.000
O02.9 Abnormal product of conception, unspecified
0.000 0.983 0.016
O02.8 Other specified abnormal products of conception
0.000 0.983 0.016
E04.2 Non-toxic multinodular goitre
0.017 0.983 0.000
O02.0 Blighted ovum and nonhydatidiform mole
0.000 0.984 0.016
Q60-Q64 Congenital malformations of the urinary system
0.000 0.984 0.016
E04.0 Non-toxic diffuse goitre
0.015 0.985 0.000
C43.5 Malignant melanoma of trunk
0.000 0.986 0.014
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.986 0.014
C43 Malignant melanoma of skin
0.000 0.986 0.014
Q63 Other congenital malformations of kidney
0.000 0.987 0.013
E04.8 Other specified non-toxic goitre
0.013 0.987 0.000
R59.1 Generalised enlarged lymph nodes
0.000 0.987 0.013
O04.9 Complete or unspecified, without complication
0.000 0.988 0.012
Q60 Renal agenesis and other reduction defects of kidney
0.000 0.988 0.012
C43.9 Malignant melanoma of skin, unspecified
0.000 0.988 0.012
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.000 0.988 0.012
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.988 0.012
Q63.0 Accessory kidney
0.000 0.988 0.012
O04 Medical abortion
0.000 0.989 0.011
O00-O08 Pregnancy with abortive outcome
0.000 0.989 0.011
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.989 0.011
C43.7 Malignant melanoma of lower limb, including hip
0.000 0.989 0.011
Q63.1 Lobulated, fused and horseshoe kidney
0.000 0.989 0.010
C43.8 Overlapping malignant melanoma of skin
0.000 0.990 0.010
C43.1 Malignant melanoma of eyelid, including canthus
0.000 0.990 0.010
C43.0 Malignant melanoma of lip
0.000 0.990 0.010
Y84.0 Cardiac catheterisation
0.000 0.990 0.010
Q63.9 Congenital malformation of kidney, unspecified
0.000 0.990 0.010
Q63.8 Other specified congenital malformations of kidney
0.000 0.990 0.010
Q63.3 Hyperplastic and giant kidney
0.000 0.990 0.010
Q63.2 Ectopic kidney
0.000 0.990 0.010
Q60.0 Renal agenesis, unilateral
0.000 0.990 0.010
Q62.5 Duplication of ureter
0.000 0.991 0.009
Q64 Other congenital malformations of urinary system
0.000 0.991 0.009
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.000 0.991 0.009
Q60.2 Renal agenesis, unspecified
0.000 0.991 0.009
N80.0 Endometriosis of uterus
0.000 0.991 0.009
Q60.6 Potter's syndrome
0.000 0.991 0.009
Q60.5 Renal hypoplasia, unspecified
0.000 0.991 0.009
Q60.4 Renal hypoplasia, bilateral
0.000 0.991 0.009
Q60.3 Renal hypoplasia, unilateral
0.000 0.991 0.009
Q60.1 Renal agenesis, bilateral
0.000 0.991 0.009
Q62.8 Other congenital malformations of ureter
0.000 0.991 0.009
Q62.7 Congenital vesico-uretero-renal reflux
0.000 0.991 0.009
Q62.6 Malposition of ureter
0.000 0.991 0.009
Q62.4 Agenesis of ureter
0.000 0.991 0.009
Q62.3 Other obstructive defects of renal pelvis and ureter
0.000 0.991 0.009
Q62.2 Congenital megaloureter
0.000 0.991 0.009
Q62.1 Atresia and stenosis of ureter
0.000 0.991 0.009
Q62.0 Congenital hydronephrosis
0.000 0.991 0.009
O04.4 Incomplete, without complication
0.000 0.991 0.008
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.000 0.991 0.009
Y84.2 Radiological procedure and radiotherapy
0.000 0.992 0.008
E28.2 Polycystic ovarian syndrome
0.008 0.992 0.000
O04.8 Complete or unspecified, with other and unspecified complications
0.000 0.992 0.008
O04.7 Complete or unspecified, complicated by embolism
0.000 0.992 0.008
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.000 0.992 0.008
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.000 0.992 0.008
O04.3 Incomplete, with other and unspecified complications
0.000 0.992 0.008
O04.2 Incomplete, complicated by embolism
0.000 0.992 0.008
O04.0 Incomplete, complicated by genital tract and pelvic infection
0.000 0.992 0.008
R59 Enlarged lymph nodes
0.000 0.992 0.008
C43.4 Malignant melanoma of scalp and neck
0.000 0.992 0.008
E04.1 Non-toxic single thyroid nodule
0.008 0.992 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.000 0.992 0.008
O07 Failed attempted abortion
0.000 0.992 0.008
O06 Unspecified abortion
0.000 0.992 0.008
O05 Other abortion
0.000 0.992 0.008
O01 Hydatidiform mole
0.000 0.992 0.008
Y84.1 Kidney dialysis
0.000 0.992 0.008
R59.9 Enlarged lymph nodes, unspecified
0.000 0.993 0.007
Y84.6 Urinary catheterisation
0.000 0.993 0.007
Q64.9 Congenital malformation of urinary system, unspecified
0.000 0.993 0.007
Q64.8 Other specified congenital malformations of urinary system
0.000 0.993 0.007
Q64.7 Other congenital malformations of bladder and urethra
0.000 0.993 0.007
Q64.6 Congenital diverticulum of bladder
0.000 0.993 0.007
Q64.5 Congenital absence of bladder and urethra
0.000 0.993 0.007
Q64.2 Congenital posterior urethral valves
0.000 0.993 0.007
Q64.1 Exstrophy of urinary bladder
0.000 0.993 0.007
Q64.0 Epispadias
0.000 0.993 0.007
O04.1 Incomplete, complicated by delayed or excessive haemorrhage
0.000 0.993 0.007
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.007 0.993 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.000 0.993 0.007
M89.87 Other specified disorders of bone (Ankle and foot)
0.007 0.993 0.000
R59.0 Localised enlarged lymph nodes
0.000 0.993 0.007
E28 Ovarian dysfunction
0.007 0.993 0.000
Y84.4 Aspiration of fluid
0.000 0.993 0.007
Q64.3 Other atresia and stenosis of urethra and bladder neck
0.000 0.993 0.006
Z30 Contraceptive management
0.000 0.993 0.007
E28.3 Primary ovarian failure
0.006 0.993 0.000
Y84.7 Blood-sampling
0.000 0.994 0.006
Y84.5 Insertion of gastric or duodenal sound
0.000 0.994 0.006
Y84.3 Shock therapy
0.000 0.994 0.006
O01.9 Hydatidiform mole, unspecified
0.000 0.994 0.006
O01.1 Incomplete and partial hydatidiform mole
0.000 0.994 0.006
O01.0 Classical hydatidiform mole
0.000 0.994 0.006
O05.9 Complete or unspecified, without complication
0.000 0.994 0.006
O05.8 Complete or unspecified, with other and unspecified complications
0.000 0.994 0.006
O05.7 Complete or unspecified, complicated by embolism
0.000 0.994 0.006
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.000 0.994 0.006
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.000 0.994 0.006
O05.4 Incomplete, without complication
0.000 0.994 0.006
O05.3 Incomplete, with other and unspecified complications
0.000 0.994 0.006
O05.2 Incomplete, complicated by embolism
0.000 0.994 0.006
O05.1 Incomplete, complicated by delayed or excessive haemorrhage
0.000 0.994 0.006
O05.0 Incomplete, complicated by genital tract and pelvic infection
0.000 0.994 0.006
O06.9 Complete or unspecified, without complication
0.000 0.994 0.006
O06.8 Complete or unspecified, with other and unspecified complications
0.000 0.994 0.006
O06.7 Complete or unspecified, complicated by embolism
0.000 0.994 0.006
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.000 0.994 0.006
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.000 0.994 0.006
O06.4 Incomplete, without complication
0.000 0.994 0.006
O06.3 Incomplete, with other and unspecified complications
0.000 0.994 0.006
O06.2 Incomplete, complicated by embolism
0.000 0.994 0.006
O06.1 Incomplete, complicated by delayed or excessive haemorrhage
0.000 0.994 0.006
O06.0 Incomplete, complicated by genital tract and pelvic infection
0.000 0.994 0.006
O07.9 Other and unspecified failed attempted abortion, without complication
0.000 0.994 0.006
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications
0.000 0.994 0.006
O07.7 Other and unspecified failed attempted abortion, complicated by embolism
0.000 0.994 0.006
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage
0.000 0.994 0.006
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection
0.000 0.994 0.006
O07.4 Failed medical abortion, without complication
0.000 0.994 0.006
O07.3 Failed medical abortion, with other and unspecified complications
0.000 0.994 0.006
O07.2 Failed medical abortion, complicated by embolism
0.000 0.994 0.006
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage
0.000 0.994 0.006
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection
0.000 0.994 0.006
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified
0.000 0.994 0.006
O08.8 Other complications following abortion and ectopic and molar pregnancy
0.000 0.994 0.006
O08.7 Other venous complications following abortion and ectopic and molar pregnancy
0.000 0.994 0.006
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy
0.000 0.994 0.006
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy
0.000 0.994 0.006
O08.4 Renal failure following abortion and ectopic and molar pregnancy
0.000 0.994 0.006
O08.3 Shock following abortion and ectopic and molar pregnancy
0.000 0.994 0.006
O08.2 Embolism following abortion and ectopic and molar pregnancy
0.000 0.994 0.006
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy
0.000 0.994 0.006
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy
0.000 0.994 0.006
Y84.9 Medical procedure, unspecified
0.000 0.994 0.006
O00 Ectopic pregnancy
0.001 0.994 0.005
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.000 0.994 0.006
Q64.4 Malformation of urachus
0.001 0.994 0.005
E00-E07 Disorders of thyroid gland
0.005 0.995 0.000
Z30.8 Other contraceptive management
0.000 0.995 0.005
E28.9 Ovarian dysfunction, unspecified
0.005 0.995 0.000
E28.8 Other ovarian dysfunction
0.005 0.995 0.000
E28.1 Androgen excess
0.005 0.995 0.000
E28.0 Oestrogen excess
0.005 0.995 0.000
Z30.9 Contraceptive management, unspecified
0.000 0.995 0.005
Z30.4 Surveillance of contraceptive drugs
0.000 0.995 0.005
E03.8 Other specified hypothyroidism
0.005 0.995 0.000
E06 Thyroiditis
0.005 0.995 0.000
Z30.0 General counselling and advice on contraception
0.000 0.995 0.005
Z30.3 Menstrual extraction
0.000 0.995 0.005
E87.2 Acidosis
0.000 0.995 0.005
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.995 0.005
I08.0 Disorders of both mitral and aortic valves
0.000 0.995 0.005
M89.8 Other specified disorders of bone
0.005 0.995 0.000
O00.9 Ectopic pregnancy, unspecified
0.000 0.995 0.004
O00.8 Other ectopic pregnancy
0.001 0.995 0.004
O00.2 Ovarian pregnancy
0.001 0.995 0.004
O00.0 Abdominal pregnancy
0.001 0.995 0.004
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.996 0.004
E06.3 Autoimmune thyroiditis
0.004 0.996 0.000
Z11.2 Special screening examination for other bacterial diseases
0.004 0.996 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.996 0.004
E03 Other hypothyroidism
0.004 0.996 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.004 0.996 0.000
E00 Congenital iodine-deficiency syndrome
0.004 0.996 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.004 0.996 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.996 0.004
I84.2 Internal haemorrhoids without complication
0.000 0.996 0.004
Z11.0 Special screening examination for intestinal infectious diseases
0.004 0.996 0.000
E87.5 Hyperkalaemia
0.000 0.996 0.004
O03 Spontaneous abortion
0.000 0.996 0.004
E06.9 Thyroiditis, unspecified
0.004 0.996 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.004 0.996 0.000
Y83.4 Other reconstructive surgery
0.000 0.996 0.004
M89.86 Other specified disorders of bone (Lower leg)
0.004 0.996 0.000
N80.8 Other endometriosis
0.000 0.996 0.004
N80 Endometriosis
0.000 0.996 0.004
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.000 0.996 0.004
Z11 Special screening examination for infectious and parasitic diseases
0.004 0.996 0.000
Y83.3 Surgical operation with formation of external stoma
0.000 0.996 0.004
Z30.1 Insertion of (intra-uterine) contraceptive device
0.000 0.996 0.004
E06.5 Other chronic thyroiditis
0.004 0.996 0.000
E06.4 Drug-induced thyroiditis
0.004 0.996 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.004 0.996 0.000
E06.1 Subacute thyroiditis
0.004 0.996 0.000
E06.0 Acute thyroiditis
0.004 0.996 0.000
N80.2 Endometriosis of Fallopian tube
0.000 0.996 0.004
E07 Other disorders of thyroid
0.004 0.996 0.000
M89.84 Other specified disorders of bone (Hand)
0.003 0.996 0.000
E87.3 Alkalosis
0.000 0.996 0.004
M89.85 Other specified disorders of bone (Pelvic region and thigh)
0.003 0.996 0.000
M89.89 Other specified disorders of bone (Site unspecified)
0.003 0.996 0.000
M89.83 Other specified disorders of bone (Forearm)
0.003 0.996 0.000
M89.82 Other specified disorders of bone (Upper arm)
0.003 0.996 0.000
M89.81 Other specified disorders of bone (Shoulder region)
0.003 0.996 0.000
M89.80 Other specified disorders of bone (Multiple sites)
0.003 0.996 0.000
L03.3 Cellulitis of trunk
0.000 0.996 0.004
E20-E35 Disorders of other endocrine glands
0.004 0.996 0.000
E87.0 Hyperosmolality and hypernatraemia
0.000 0.996 0.003
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.000 0.996 0.003
M13.97 Arthritis, unspecified (Ankle and foot)
0.003 0.997 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.997 0.003
N80.5 Endometriosis of intestine
0.000 0.997 0.003
R87.6 Abnormal cytological findings
0.000 0.997 0.003
Z11.5 Special screening examination for other viral diseases
0.003 0.997 0.000
E03.5 Myxoedema coma
0.003 0.997 0.000
E03.4 Atrophy of thyroid (acquired)
0.003 0.997 0.000
E03.3 Postinfectious hypothyroidism
0.003 0.997 0.000
E03.1 Congenital hypothyroidism without goitre
0.003 0.997 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.003 0.997 0.000
E24 Cushing's syndrome
0.003 0.997 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.003 0.997 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.003 0.997 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.003 0.997 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.003 0.997 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.003 0.997 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.003 0.997 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.003 0.997 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.003 0.997 0.000
Z11.4 Special screening examination for human immunodeficiency virus [HIV]
0.003 0.997 0.000
E87.4 Mixed disorder of acid-base balance
0.000 0.997 0.003
F10.0 Acute intoxication
0.000 0.997 0.003
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.997 0.003
O03.8 Complete or unspecified, with other and unspecified complications
0.000 0.997 0.003
O03.7 Complete or unspecified, complicated by embolism
0.000 0.997 0.003
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.000 0.997 0.003
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.000 0.997 0.003
O03.3 Incomplete, with other and unspecified complications
0.000 0.997 0.003
O03.2 Incomplete, complicated by embolism
0.000 0.997 0.003
O03.0 Incomplete, complicated by genital tract and pelvic infection
0.000 0.997 0.003
Z11.8 Special screening examination for other infectious and parasitic diseases
0.003 0.997 0.000
E27 Other disorders of adrenal gland
0.003 0.997 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.000 0.997 0.003
Z11.9 Special screening examination for infectious and parasitic diseases, unspecified
0.003 0.997 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.000 0.997 0.003
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.000 0.997 0.003
Z11.6 Special screening examination for other protozoal diseases and helminthiases
0.003 0.997 0.000
Z11.3 Special screening examination for infections with a predominantly sexual mode of transmission
0.003 0.997 0.000
E07.8 Other specified disorders of thyroid
0.003 0.997 0.000
M89.88 Other specified disorders of bone (Other)
0.003 0.997 0.000
E22.0 Acromegaly and pituitary gigantism
0.003 0.997 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.003 0.997 0.000
Z11.1 Special screening examination for respiratory tuberculosis
0.003 0.997 0.000
E25 Adrenogenital disorders
0.003 0.997 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.003 0.997 0.000
E27.8 Other specified disorders of adrenal gland
0.003 0.997 0.000
E22 Hyperfunction of pituitary gland
0.003 0.997 0.000
E24.0 Pituitary-dependent Cushing's disease
0.003 0.997 0.000
E07.1 Dyshormogenetic goitre
0.003 0.997 0.000
E07.0 Hypersecretion of calcitonin
0.003 0.997 0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage
0.000 0.997 0.003
N80.6 Endometriosis in cutaneous scar
0.000 0.997 0.003
M76.67 Achilles tendinitis (Ankle and foot)
0.003 0.997 0.000
E87.7 Fluid overload
0.000 0.997 0.003
E20 Hypoparathyroidism
0.003 0.997 0.000
E24.2 Drug-induced Cushing's syndrome
0.003 0.997 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.003 0.997 0.000
E32 Diseases of thymus
0.003 0.997 0.000
E31 Polyglandular dysfunction
0.003 0.997 0.000
E30 Disorders of puberty, not elsewhere classified
0.003 0.997 0.000
Y84.8 Other medical procedures
0.000 0.997 0.003
Y83.0 Surgical operation with transplant of whole organ
0.000 0.997 0.003
E26 Hyperaldosteronism
0.003 0.997 0.000
E27.9 Disorder of adrenal gland, unspecified
0.003 0.997 0.000
H21.8 Other specified disorders of iris and ciliary body
0.003 0.997 0.000
I21.4 Acute subendocardial myocardial infarction
0.000 0.997 0.003
M25.47 Effusion of joint (Ankle and foot)
0.003 0.997 0.000
E24.9 Cushing's syndrome, unspecified
0.003 0.997 0.000
N92.6 Irregular menstruation, unspecified
0.000 0.997 0.003
M89 Other disorders of bone
0.003 0.997 0.000
O03.9 Complete or unspecified, without complication
0.000 0.997 0.003
J33.8 Other polyp of sinus
0.003 0.997 0.000
O00.1 Tubal pregnancy
0.002 0.997 0.001
Y83.1 Surgical operation with implant of artificial internal device
0.000 0.997 0.003
E24.8 Other Cushing's syndrome
0.002 0.997 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.002 0.997 0.000
E24.3 Ectopic ACTH syndrome
0.002 0.997 0.000
E24.1 Nelson's syndrome
0.002 0.997 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.002 0.997 0.000
E34 Other endocrine disorders
0.002 0.997 0.000
E27.5 Adrenomedullary hyperfunction
0.002 0.997 0.000
E27.0 Other adrenocortical overactivity
0.002 0.997 0.000
M89.0 Algoneurodystrophy
0.002 0.998 0.000
Y40.0 Penicillins
0.002 0.998 0.000
N80.3 Endometriosis of pelvic peritoneum
0.000 0.998 0.002
E27.4 Other and unspecified adrenocortical insufficiency
0.002 0.998 0.000
M89.5 Osteolysis
0.002 0.998 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.000 0.998 0.002
E25.9 Adrenogenital disorder, unspecified
0.002 0.998 0.000
E25.8 Other adrenogenital disorders
0.002 0.998 0.000
E23 Hypofunction and other disorders of pituitary gland
0.002 0.998 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.998 0.002
E22.9 Hyperfunction of pituitary gland, unspecified
0.002 0.998 0.000
E22.8 Other hyperfunction of pituitary gland
0.002 0.998 0.000
E29 Testicular dysfunction
0.002 0.998 0.000
M54.36 Sciatica (Lumbar region)
0.000 0.998 0.002
E20.9 Hypoparathyroidism, unspecified
0.002 0.998 0.000
E20.8 Other hypoparathyroidism
0.002 0.998 0.000
E20.1 Pseudohypoparathyroidism
0.002 0.998 0.000
E20.0 Idiopathic hypoparathyroidism
0.002 0.998 0.000
E23.0 Hypopituitarism
0.002 0.998 0.000
E30.9 Disorder of puberty, unspecified
0.002 0.998 0.000
E30.8 Other disorders of puberty
0.002 0.998 0.000
E30.1 Precocious puberty
0.002 0.998 0.000
E30.0 Delayed puberty
0.002 0.998 0.000
E31.9 Polyglandular dysfunction, unspecified
0.002 0.998 0.000
E31.8 Other polyglandular dysfunction
0.002 0.998 0.000
E31.1 Polyglandular hyperfunction
0.002 0.998 0.000
E31.0 Autoimmune polyglandular failure
0.002 0.998 0.000
E32.9 Disease of thymus, unspecified
0.002 0.998 0.000
E32.8 Other diseases of thymus
0.002 0.998 0.000
E32.1 Abscess of thymus
0.002 0.998 0.000
E32.0 Persistent hyperplasia of thymus
0.002 0.998 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.002 0.998 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.002 0.998 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.002 0.998 0.000
H21 Other disorders of iris and ciliary body
0.002 0.998 0.000
B02.9 Zoster without complication
0.002 0.998 0.000
E26.9 Hyperaldosteronism, unspecified
0.002 0.998 0.000
E26.8 Other hyperaldosteronism
0.002 0.998 0.000
E26.1 Secondary hyperaldosteronism
0.002 0.998 0.000
M89.04 Algoneurodystrophy (Hand)
0.002 0.998 0.000
E34.0 Carcinoid syndrome
0.002 0.998 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.998 0.002
M89.55 Osteolysis (Pelvic region and thigh)
0.002 0.998 0.000
E21.4 Other specified disorders of parathyroid gland
0.002 0.998 0.000
M89.6 Osteopathy after poliomyelitis
0.002 0.998 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.002 0.998 0.000
M89.2 Other disorders of bone development and growth
0.002 0.998 0.000
M89.1 Epiphyseal arrest
0.002 0.998 0.000
C71.1 Frontal lobe
0.002 0.998 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.002 0.998 0.000
E22.1 Hyperprolactinaemia
0.002 0.998 0.000
E26.0 Primary hyperaldosteronism
0.002 0.998 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.000 0.998 0.002
R07.3 Other chest pain
0.000 0.998 0.002
E27.1 Primary adrenocortical insufficiency
0.002 0.998 0.000
H21.2 Degeneration of iris and ciliary body
0.002 0.998 0.000
E34.5 Androgen resistance syndrome
0.002 0.998 0.000
E34.4 Constitutional tall stature
0.002 0.998 0.000
E34.3 Short stature, not elsewhere classified
0.002 0.998 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.002 0.998 0.000
E34.1 Other hypersecretion of intestinal hormones
0.002 0.998 0.000
M89.06 Algoneurodystrophy (Lower leg)
0.002 0.998 0.000
E16.1 Other hypoglycaemia
0.000 0.998 0.002
M46.9 Inflammatory spondylopathy, unspecified
0.002 0.998 0.000
M89.09 Algoneurodystrophy (Site unspecified)
0.002 0.998 0.000
S82.00 Fracture of patella (closed)
0.000 0.998 0.002
H21.9 Disorder of iris and ciliary body, unspecified
0.002 0.998 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.002 0.998 0.000
M89.08 Algoneurodystrophy (Other)
0.002 0.998 0.000
M89.07 Algoneurodystrophy (Ankle and foot)
0.002 0.998 0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)
0.002 0.998 0.000
M89.02 Algoneurodystrophy (Upper arm)
0.002 0.998 0.000
M89.01 Algoneurodystrophy (Shoulder region)
0.002 0.998 0.000
M89.00 Algoneurodystrophy (Multiple sites)
0.002 0.998 0.000
E27.2 Addisonian crisis
0.002 0.998 0.000
M89.3 Hypertrophy of bone
0.002 0.998 0.000
M89.59 Osteolysis (Site unspecified)
0.002 0.998 0.000
M89.58 Osteolysis (Other)
0.002 0.998 0.000
M89.57 Osteolysis (Ankle and foot)
0.002 0.998 0.000
M89.56 Osteolysis (Lower leg)
0.002 0.998 0.000
M89.54 Osteolysis (Hand)
0.002 0.998 0.000
M89.53 Osteolysis (Forearm)
0.002 0.998 0.000
M89.52 Osteolysis (Upper arm)
0.002 0.998 0.000
M89.51 Osteolysis (Shoulder region)
0.002 0.998 0.000
M89.50 Osteolysis (Multiple sites)
0.002 0.998 0.000
M89.9 Disorder of bone, unspecified
0.002 0.998 0.000
I08 Multiple valve diseases
0.000 0.998 0.002
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.002 0.998 0.000
E23.1 Drug-induced hypopituitarism
0.002 0.998 0.000
Y83.5 Amputation of limb(s)
0.000 0.998 0.002
M89.03 Algoneurodystrophy (Forearm)
0.002 0.998 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.998 0.002
E29.9 Testicular dysfunction, unspecified
0.002 0.998 0.000
E29.8 Other testicular dysfunction
0.002 0.998 0.000
E29.0 Testicular hyperfunction
0.002 0.998 0.000
H21.1 Other vascular disorders of iris and ciliary body
0.002 0.998 0.000
M76.6 Achilles tendinitis
0.002 0.998 0.000
E07.9 Disorder of thyroid, unspecified
0.002 0.998 0.000
L53.9 Erythematous condition, unspecified
0.000 0.998 0.002
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.002 0.998 0.000
E23.6 Other disorders of pituitary gland
0.002 0.998 0.000
H21.4 Pupillary membranes
0.002 0.998 0.000
H21.3 Cyst of iris, ciliary body and anterior chamber
0.002 0.998 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.998 0.002
S62.30 Fracture of other metacarpal bone (closed)
0.000 0.998 0.002
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.998 0.001
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.998 0.001
E16.4 Abnormal secretion of gastrin
0.000 0.998 0.001
E16.3 Increased secretion of glucagon
0.000 0.998 0.001
E87.6 Hypokalaemia
0.000 0.998 0.002
M89.19 Epiphyseal arrest (Site unspecified)
0.002 0.998 0.000
M89.18 Epiphyseal arrest (Other)
0.002 0.998 0.000
M89.17 Epiphyseal arrest (Ankle and foot)
0.002 0.998 0.000
M89.16 Epiphyseal arrest (Lower leg)
0.002 0.998 0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)
0.002 0.998 0.000
M89.14 Epiphyseal arrest (Hand)
0.002 0.998 0.000
M89.13 Epiphyseal arrest (Forearm)
0.002 0.998 0.000
M89.12 Epiphyseal arrest (Upper arm)
0.002 0.998 0.000
M89.11 Epiphyseal arrest (Shoulder region)
0.002 0.998 0.000
M89.10 Epiphyseal arrest (Multiple sites)
0.002 0.998 0.000
M89.29 Other disorders of bone development and growth (Site unspecified)
0.002 0.998 0.000
M89.28 Other disorders of bone development and growth (Other)
0.002 0.998 0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)
0.002 0.998 0.000
M89.26 Other disorders of bone development and growth (Lower leg)
0.002 0.998 0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)
0.002 0.998 0.000
M89.24 Other disorders of bone development and growth (Hand)
0.002 0.998 0.000
M89.23 Other disorders of bone development and growth (Forearm)
0.002 0.998 0.000
M89.22 Other disorders of bone development and growth (Upper arm)
0.002 0.998 0.000
M89.21 Other disorders of bone development and growth (Shoulder region)
0.002 0.998 0.000
M89.20 Other disorders of bone development and growth (Multiple sites)
0.002 0.998 0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)
0.002 0.998 0.000
M89.48 Other hypertrophic osteoarthropathy (Other)
0.002 0.998 0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)
0.002 0.998 0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)
0.002 0.998 0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)
0.002 0.998 0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)
0.002 0.998 0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)
0.002 0.998 0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)
0.002 0.998 0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)
0.002 0.998 0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)
0.002 0.998 0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)
0.002 0.998 0.000
M89.68 Osteopathy after poliomyelitis (Other)
0.002 0.998 0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)
0.002 0.998 0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)
0.002 0.998 0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)
0.002 0.998 0.000
M89.64 Osteopathy after poliomyelitis (Hand)
0.002 0.998 0.000
M89.63 Osteopathy after poliomyelitis (Forearm)
0.002 0.998 0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)
0.002 0.998 0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)
0.002 0.998 0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)
0.002 0.998 0.000
G59.0 Diabetic mononeuropathy
0.000 0.998 0.002
Z29.1 Prophylactic immunotherapy
0.002 0.998 0.000
E34.9 Endocrine disorder, unspecified
0.002 0.998 0.000
M76.66 Achilles tendinitis (Lower leg)
0.002 0.998 0.000
E34.8 Other specified endocrine disorders
0.002 0.998 0.000
R63.0 Anorexia
0.000 0.998 0.002
R87 Abnormal findings in specimens from female genital organs
0.000 0.998 0.002
G55.3 Nerve root and plexus compressions in other dorsopathies
0.000 0.998 0.002
H21.0 Hyphaema
0.002 0.998 0.000
Q44.6 Cystic disease of liver
0.000 0.998 0.002
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.000 0.998 0.002
F10 Mental and behavioural disorders due to use of alcohol
0.000 0.998 0.002
Q21.1 Atrial septal defect
0.000 0.998 0.002
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.000 0.998 0.002
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.002 0.998 0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.002 0.998 0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.002 0.998 0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.002 0.998 0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.002 0.998 0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.002 0.998 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.002 0.998 0.000
E21.2 Other hyperparathyroidism
0.002 0.998 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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