TreeWAS – Variant ID: rs12438659

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.000	1.000
J44 Other chronic obstructive pulmonary disease	0.000	0.000	1.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.000	1.000
J40-J47 Chronic lower respiratory diseases	0.000	0.000	1.000
J43.9 Emphysema, unspecified	0.000	0.000	1.000
I71 Aortic aneurysm and dissection	0.000	0.000	1.000
J43 Emphysema	0.000	0.000	1.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.000	1.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.001	0.999
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.004	0.996
Chapter X Diseases of the respiratory system	0.000	0.005	0.995
I73 Other peripheral vascular diseases	0.000	0.006	0.994
J90-J94 Other diseases of pleura	0.000	0.008	0.992
I70 Atherosclerosis	0.000	0.008	0.992
J92 Pleural plaque	0.000	0.012	0.988
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.014	0.986
I73.9 Peripheral vascular disease, unspecified	0.000	0.014	0.986
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.018	0.982
J42 Unspecified chronic bronchitis	0.000	0.019	0.981
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.026	0.974
J92.0 Pleural plaque with presence of asbestos	0.000	0.029	0.971
I60-I69 Cerebrovascular diseases	0.000	0.031	0.969
Chapter IX Diseases of the circulatory system	0.000	0.034	0.966
J60-J70 Lung diseases due to external agents	0.000	0.035	0.965
J95-J99 Other diseases of the respiratory system	0.000	0.037	0.963
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.042	0.958
I60 Subarachnoid haemorrhage	0.000	0.048	0.952
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.000	0.057	0.943
I67 Other cerebrovascular diseases	0.000	0.059	0.941
J98 Other respiratory disorders	0.000	0.062	0.938
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.063	0.937
J92.9 Pleural plaque without asbestos	0.000	0.064	0.936
I77 Other disorders of arteries and arterioles	0.000	0.071	0.929
J98.1 Pulmonary collapse	0.000	0.073	0.927
I69 Sequelae of cerebrovascular disease	0.000	0.073	0.927
J90 Pleural effusion, not elsewhere classified	0.000	0.077	0.923
I26 Pulmonary embolism	0.000	0.081	0.919
I27 Other pulmonary heart diseases	0.000	0.082	0.918
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.094	0.906
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.000	0.095	0.905
I27.9 Pulmonary heart disease, unspecified	0.000	0.098	0.902
I67.9 Cerebrovascular disease, unspecified	0.000	0.109	0.891
I72 Other aneurysm	0.000	0.118	0.882
I73.0 Raynaud's syndrome	0.000	0.124	0.876
I69.3 Sequelae of cerebral infarction	0.000	0.129	0.871
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.000	0.139	0.861
J86 Pyothorax	0.000	0.146	0.854
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.154	0.846
I77.1 Stricture of artery	0.000	0.163	0.837
I60.8 Other subarachnoid haemorrhage	0.000	0.164	0.836
J43.2 Centrilobular emphysema	0.000	0.167	0.833
I67.8 Other specified cerebrovascular diseases	0.000	0.170	0.830
J93 Pneumothorax	0.000	0.176	0.824
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.176	0.824
J98.4 Other disorders of lung	0.000	0.177	0.823
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.177	0.823
J86.9 Pyothorax without fistula	0.000	0.179	0.821
I67.1 Cerebral aneurysm, nonruptured	0.000	0.184	0.816
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.185	0.815
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.192	0.808
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.193	0.807
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.195	0.805
I72.0 Aneurysm of carotid artery	0.000	0.196	0.804
I77.0 Arteriovenous fistula, acquired	0.000	0.199	0.801
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.208	0.792
I71.0 Dissection of aorta [any part]	0.000	0.214	0.786
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.229	0.770
I70.0 Atherosclerosis of aorta	0.000	0.233	0.767
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.235	0.765
J60 Coalworker's pneumoconiosis	0.000	0.237	0.763
J98.9 Respiratory disorder, unspecified	0.000	0.240	0.760
J93.1 Other spontaneous pneumothorax	0.000	0.240	0.760
J99 Respiratory disorders in diseases classified elsewhere	0.000	0.253	0.747
J64 Unspecified pneumoconiosis	0.000	0.253	0.747
I72.8 Aneurysm of other specified arteries	0.000	0.263	0.737
I77.2 Rupture of artery	0.000	0.273	0.727
J41 Simple and mucopurulent chronic bronchitis	0.000	0.283	0.717
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.283	0.717
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.283	0.717
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.283	0.717
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.283	0.717
J43.1 Panlobular emphysema	0.000	0.283	0.717
J43.0 MacLeod's syndrome	0.000	0.283	0.717
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.287	0.712
I70.9 Generalised and unspecified atherosclerosis	0.000	0.289	0.711
I70.8 Atherosclerosis of other arteries	0.000	0.289	0.711
I28 Other diseases of pulmonary vessels	0.000	0.302	0.698
I78 Diseases of capillaries	0.000	0.302	0.698
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.303	0.697
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.305	0.694
I61 Intracerebral haemorrhage	0.000	0.308	0.692
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.000	0.308	0.692
J66 Airway disease due to specific organic dust	0.000	0.308	0.692
J63 Pneumoconiosis due to other inorganic dusts	0.000	0.308	0.692
J62 Pneumoconiosis due to dust containing silica	0.000	0.308	0.692
J65 Pneumoconiosis associated with tuberculosis	0.000	0.308	0.692
J96 Respiratory failure, not elsewhere classified	0.000	0.310	0.690
I00-I02 Acute rheumatic fever	0.000	0.310	0.689
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.311	0.689
J98.2 Interstitial emphysema	0.000	0.314	0.686
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.317	0.683
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.317	0.683
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.319	0.681
J69 Pneumonitis due to solids and liquids	0.000	0.320	0.680
I72.9 Aneurysm of unspecified site	0.000	0.323	0.677
I27.8 Other specified pulmonary heart diseases	0.000	0.323	0.677
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.326	0.674
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.326	0.674
I67.5 Moyamoya disease	0.000	0.326	0.674
I67.4 Hypertensive encephalopathy	0.000	0.326	0.674
I67.3 Progressive vascular leukoencephalopathy	0.000	0.326	0.674
J98.3 Compensatory emphysema	0.000	0.327	0.673
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.330	0.669
I77.5 Necrosis of artery	0.000	0.334	0.666
I77.4 Coeliac artery compression syndrome	0.000	0.334	0.666
I27.1 Kyphoscoliotic heart disease	0.000	0.342	0.658
I74 Arterial embolism and thrombosis	0.000	0.344	0.656
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.345	0.655
J95 Postprocedural respiratory disorders, not elsewhere classified	0.000	0.357	0.643
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.361	0.639
J70 Respiratory conditions due to other external agents	0.000	0.362	0.638
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.367	0.633
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.367	0.633
I72.1 Aneurysm of artery of upper extremity	0.000	0.367	0.633
I73.8 Other specified peripheral vascular diseases	0.000	0.375	0.624
J98.0 Diseases of bronchus, not elsewhere classified	0.000	0.376	0.624
J67 Hypersensitivity pneumonitis due to organic dust	0.000	0.380	0.619
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.000	0.384	0.616
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.387	0.613
J93.0 Spontaneous tension pneumothorax	0.000	0.387	0.613
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.389	0.611
I27.0 Primary pulmonary hypertension	0.000	0.392	0.608
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.394	0.606
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.395	0.605
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.399	0.601
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.403	0.597
I70.1 Atherosclerosis of renal artery	0.000	0.407	0.593
J98.6 Disorders of diaphragm	0.000	0.407	0.592
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.409	0.590
I79.1 Aortitis in diseases classified elsewhere	0.000	0.409	0.590
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.409	0.590
J85 Abscess of lung and mediastinum	0.000	0.411	0.589
J86.0 Pyothorax with fistula	0.000	0.418	0.582
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.422	0.578
J43.8 Other emphysema	0.000	0.423	0.577
J99.0 Rheumatoid lung disease	0.000	0.425	0.575
I72.3 Aneurysm of iliac artery	0.000	0.429	0.571
J40 Bronchitis, not specified as acute or chronic	0.000	0.434	0.566
I77.8 Other specified disorders of arteries and arterioles	0.000	0.440	0.559
J94 Other pleural conditions	0.000	0.443	0.557
I72.4 Aneurysm of artery of lower extremity	0.000	0.445	0.555
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.450	0.550
I77.3 Arterial fibromuscular dysplasia	0.000	0.451	0.549
I72.2 Aneurysm of renal artery	0.000	0.459	0.540
J93.8 Other pneumothorax	0.000	0.462	0.538
I67.2 Cerebral atherosclerosis	0.000	0.466	0.534
J69.8 Pneumonitis due to other solids and liquids	0.000	0.474	0.526
J95.8 Other postprocedural respiratory disorders	0.000	0.476	0.524
I77.6 Arteritis, unspecified	0.000	0.479	0.521
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.000	0.486	0.514
J41.1 Mucopurulent chronic bronchitis	0.000	0.486	0.514
J41.0 Simple chronic bronchitis	0.000	0.486	0.514
I28.8 Other specified diseases of pulmonary vessels	0.000	0.488	0.512
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.490	0.510
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.490	0.510
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.490	0.510
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.490	0.510
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.494	0.506
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.496	0.504
I62 Other nontraumatic intracranial haemorrhage	0.000	0.498	0.502
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.499	0.501
I28.1 Aneurysm of pulmonary artery	0.000	0.499	0.501
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.499	0.501
I78.9 Disease of capillaries, unspecified	0.000	0.499	0.501
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.502	0.498
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.502	0.498
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.502	0.498
I68.0 Cerebral amyloid angiopathy	0.000	0.502	0.498
J62.8 Pneumoconiosis due to other dust containing silica	0.000	0.504	0.496
J62.0 Pneumoconiosis due to talc dust	0.000	0.504	0.496
J63.8 Pneumoconiosis due to other specified inorganic dusts	0.000	0.504	0.496
J63.5 Stannosis	0.000	0.504	0.496
J63.4 Siderosis	0.000	0.504	0.496
J63.3 Graphite fibrosis (of lung)	0.000	0.504	0.496
J63.2 Berylliosis	0.000	0.504	0.496
J63.1 Bauxite fibrosis (of lung)	0.000	0.504	0.496
J63.0 Aluminosis (of lung)	0.000	0.504	0.496
J66.8 Airway disease due to other specific organic dusts	0.000	0.504	0.496
J66.2 Cannabinosis	0.000	0.504	0.496
J66.1 Flax-dresser's disease	0.000	0.504	0.496
J66.0 Byssinosis	0.000	0.504	0.496
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours	0.000	0.504	0.496
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours	0.000	0.504	0.496
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours	0.000	0.504	0.496
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours	0.000	0.504	0.496
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified	0.000	0.504	0.496
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours	0.000	0.504	0.496
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours	0.000	0.504	0.496
J96.9 Respiratory failure, unspecified	0.000	0.505	0.495
J96.1 Chronic respiratory failure	0.000	0.505	0.495
J96.0 Acute respiratory failure	0.000	0.505	0.495
I02 Rheumatic chorea	0.000	0.505	0.494
I01 Rheumatic fever with heart involvement	0.000	0.505	0.494
I27.2 Other secondary pulmonary hypertension	0.000	0.506	0.494
I00 Rheumatic fever without mention of heart involvement	0.000	0.509	0.491
J69.1 Pneumonitis due to oils and essences	0.000	0.512	0.487
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.517	0.483
I78.8 Other diseases of capillaries	0.000	0.519	0.481
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.520	0.480
J46 Status asthmaticus	0.000	0.523	0.477
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.524	0.476
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.527	0.473
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.529	0.471
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.530	0.470
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.530	0.469
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.530	0.469
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.530	0.469
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.530	0.469
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.536	0.464
I74.8 Embolism and thrombosis of other arteries	0.000	0.537	0.463
J95.5 Postprocedural subglottic stenosis	0.000	0.539	0.461
J95.4 Mendelson's syndrome	0.000	0.539	0.461
J95.3 Chronic pulmonary insufficiency following surgery	0.000	0.539	0.461
J95.2 Acute pulmonary insufficiency following nonthoracic surgery	0.000	0.539	0.461
J95.1 Acute pulmonary insufficiency following thoracic surgery	0.000	0.539	0.461
I05-I09 Chronic rheumatic heart diseases	0.000	0.542	0.458
J70.9 Respiratory conditions due to unspecified external agent	0.000	0.542	0.457
J70.8 Respiratory conditions due to other specified external agents	0.000	0.542	0.457
J70.4 Drug-induced interstitial lung disorder, unspecified	0.000	0.542	0.457
J70.3 Chronic drug-induced interstitial lung disorders	0.000	0.542	0.457
J70.2 Acute drug-induced interstitial lung disorders	0.000	0.542	0.457
J70.0 Acute pulmonary manifestations due to radiation	0.000	0.542	0.457
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.545	0.455
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.547	0.453
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.556	0.444
J67.8 Hypersensitivity pneumonitis due to other organic dusts	0.000	0.556	0.444
J67.7 Air-conditioner and humidifier lung	0.000	0.556	0.444
J67.6 Maple-bark-stripper's lung	0.000	0.556	0.444
J67.5 Mushroom-worker's lung	0.000	0.556	0.444
J67.4 Maltworker's lung	0.000	0.556	0.444
J67.3 Suberosis	0.000	0.556	0.444
J67.1 Bagassosis	0.000	0.556	0.444
J67.0 Farmer's lung	0.000	0.556	0.444
J91 Pleural effusion in conditions classified elsewhere	0.000	0.556	0.444
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.559	0.441
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.560	0.440
I74.5 Embolism and thrombosis of iliac artery	0.000	0.564	0.436
J98.8 Other specified respiratory disorders	0.000	0.567	0.433
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.567	0.433
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.567	0.432
J93.9 Pneumothorax, unspecified	0.000	0.568	0.432
J98.5 Diseases of mediastinum, not elsewhere classified	0.001	0.573	0.426
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.574	0.425
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.575	0.425
J69.0 Pneumonitis due to food and vomit	0.000	0.576	0.424
J85.1 Abscess of lung with pneumonia	0.000	0.576	0.423
J85.3 Abscess of mediastinum	0.000	0.578	0.422
J85.0 Gangrene and necrosis of lung	0.000	0.578	0.422
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust	0.000	0.588	0.412
J67.2 Bird fancier's lung	0.000	0.590	0.410
J09-J18 Influenza and pneumonia	0.000	0.591	0.409
J70.1 Chronic and other pulmonary manifestations due to radiation	0.000	0.597	0.403
J94.9 Pleural condition, unspecified	0.000	0.601	0.399
J94.0 Chylous effusion	0.000	0.601	0.399
J94.8 Other specified pleural conditions	0.000	0.601	0.399
J94.1 Fibrothorax	0.000	0.601	0.399
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.605	0.395
J95.9 Postprocedural respiratory disorder, unspecified	0.000	0.606	0.394
J20-J22 Other acute lower respiratory infections	0.000	0.608	0.392
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.609	0.391
J95.0 Tracheostomy malfunction	0.000	0.614	0.386
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.616	0.384
I61.8 Other intracerebral haemorrhage	0.000	0.619	0.380
I09 Other rheumatic heart diseases	0.000	0.632	0.368
J85.2 Abscess of lung without pneumonia	0.000	0.640	0.359
J96.09 Acute respiratory failure; Type unspecified	0.000	0.645	0.355
J96.01 Acute respiratory failure; Type II [hypercapnic]	0.000	0.645	0.355
J96.00 Acute respiratory failure; Type I [hypoxic]	0.000	0.645	0.355
J96.19 Chronic respiratory failure; Type unspecified	0.000	0.645	0.355
J96.11 Chronic respiratory failure; Type II [hypercapnic]	0.000	0.645	0.355
J96.10 Chronic respiratory failure; Type I [hypoxic]	0.000	0.645	0.355
J96.99 Respiratory failure, unspecified; Type unspecified	0.000	0.645	0.355
J96.91 Respiratory failure unspecified; Type II [hypercapnic]	0.000	0.645	0.355
J96.90 Respiratory failure, unspecified; Type I [hypoxic]	0.000	0.645	0.355
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.645	0.354
I01.8 Other acute rheumatic heart disease	0.000	0.645	0.354
I01.2 Acute rheumatic myocarditis	0.000	0.645	0.354
I01.1 Acute rheumatic endocarditis	0.000	0.645	0.354
I01.0 Acute rheumatic pericarditis	0.000	0.645	0.354
I02.9 Rheumatic chorea without heart involvement	0.000	0.645	0.354
I02.0 Rheumatic chorea with heart involvement	0.000	0.645	0.354
I07 Rheumatic tricuspid valve diseases	0.000	0.658	0.342
I62.1 Nontraumatic extradural haemorrhage	0.000	0.676	0.324
J10 Influenza due to identified influenza virus	0.000	0.679	0.321
I78.1 Naevus, nonneoplastic	0.000	0.685	0.315
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.687	0.313
J18 Pneumonia, organism unspecified	0.000	0.689	0.311
I70.10 Atherosclerosis of renal artery (without gangrene)	0.001	0.692	0.307
I05 Rheumatic mitral valve diseases	0.000	0.692	0.308
I09.9 Rheumatic heart disease, unspecified	0.000	0.696	0.304
I06 Rheumatic aortic valve diseases	0.000	0.696	0.303
J80-J84 Other respiratory diseases principally affecting the interstitium	0.001	0.699	0.300
J18.1 Lobar pneumonia, unspecified	0.000	0.702	0.298
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.000	0.707	0.293
J09 Influenza due to certain identified influenza virus	0.000	0.707	0.293
J17 Pneumonia in diseases classified elsewhere	0.000	0.722	0.278
J21 Acute bronchiolitis	0.000	0.723	0.277
J13 Pneumonia due to Streptococcus pneumoniae	0.000	0.724	0.276
J45 Asthma	0.000	0.724	0.276
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.726	0.274
J15 Bacterial pneumonia, not elsewhere classified	0.000	0.727	0.273
I09.8 Other specified rheumatic heart diseases	0.000	0.736	0.264
I09.2 Chronic rheumatic pericarditis	0.000	0.736	0.264
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.736	0.264
I09.0 Rheumatic myocarditis	0.000	0.736	0.264
J84 Other interstitial pulmonary diseases	0.000	0.737	0.263
J12 Viral pneumonia, not elsewhere classified	0.000	0.738	0.262
I07.1 Tricuspid insufficiency	0.000	0.741	0.259
J20 Acute bronchitis	0.000	0.744	0.256
I05.1 Rheumatic mitral insufficiency	0.000	0.747	0.253
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.000	0.748	0.252
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.000	0.752	0.247
J94.2 Haemothorax	0.001	0.754	0.245
I07.9 Tricuspid valve disease, unspecified	0.000	0.755	0.245
I07.8 Other tricuspid valve diseases	0.000	0.755	0.245
I07.2 Tricuspid stenosis with insufficiency	0.000	0.755	0.245
I07.0 Tricuspid stenosis	0.000	0.755	0.245
J10.0 Influenza with pneumonia, influenza virus identified	0.000	0.762	0.238
J14 Pneumonia due to Haemophilus influenzae	0.000	0.764	0.236
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.768	0.232
J10.8 Influenza with other manifestations, influenza virus identified	0.000	0.770	0.230
I99 Other and unspecified disorders of circulatory system	0.000	0.772	0.228
J00-J06 Acute upper respiratory infections	0.000	0.773	0.227
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.775	0.224
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.775	0.224
J18.2 Hypostatic pneumonia, unspecified	0.000	0.777	0.223
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.777	0.222
I05.0 Mitral stenosis	0.000	0.779	0.221
I05.8 Other mitral valve diseases	0.000	0.779	0.221
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.781	0.219
I63 Cerebral infarction	0.000	0.781	0.219
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.782	0.218
I06.8 Other rheumatic aortic valve diseases	0.000	0.782	0.218
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.782	0.218
I06.1 Rheumatic aortic insufficiency	0.000	0.782	0.218
Z72.0 Tobacco use	0.000	0.783	0.217
Z72.1 Alcohol use	0.000	0.785	0.215
I10-I15 Hypertensive diseases	0.000	0.785	0.215
Z72 Problems related to lifestyle	0.000	0.788	0.212
J16.8 Pneumonia due to other specified infectious organisms	0.000	0.790	0.210
J16.0 Chlamydial pneumonia	0.000	0.790	0.210
J15.2 Pneumonia due to staphylococcus	0.000	0.790	0.210
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.792	0.207
J15.8 Other bacterial pneumonia	0.000	0.792	0.208
J15.5 Pneumonia due to Escherichia coli	0.000	0.795	0.205
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.797	0.203
J18.8 Other pneumonia, organism unspecified	0.000	0.797	0.203
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.799	0.201
I05.2 Mitral stenosis with insufficiency	0.000	0.799	0.201
J15.4 Pneumonia due to other streptococci	0.000	0.800	0.200
J17.8 Pneumonia in other diseases classified elsewhere	0.000	0.800	0.199
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.000	0.801	0.199
J21.8 Acute bronchiolitis due to other specified organisms	0.000	0.801	0.199
J21.1 Acute bronchiolitis due to human metapneumovirus	0.000	0.801	0.199
J21.0 Acute bronchiolitis due to respiratory syncytial virus	0.000	0.801	0.199
J45.8 Mixed asthma	0.000	0.802	0.198
J45.1 Nonallergic asthma	0.000	0.802	0.198
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.803	0.197
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.803	0.197
I98.0 Cardiovascular syphilis	0.000	0.803	0.197
J15.3 Pneumonia due to streptococcus, group B	0.000	0.804	0.196
J21.9 Acute bronchiolitis, unspecified	0.000	0.806	0.194
I06.0 Rheumatic aortic stenosis	0.000	0.807	0.193
J15.9 Bacterial pneumonia, unspecified	0.000	0.807	0.193
I95 Hypotension	0.000	0.809	0.191
J84.0 Alveolar and parietoalveolar conditions	0.000	0.811	0.189
J12.8 Other viral pneumonia	0.000	0.812	0.188
J12.3 Human metapneumovirus pneumonia	0.000	0.812	0.188
J12.2 Parainfluenza virus pneumonia	0.000	0.812	0.188
J12.1 Respiratory syncytial virus pneumonia	0.000	0.812	0.188
J12.0 Adenoviral pneumonia	0.000	0.812	0.188
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.813	0.187
J84.8 Other specified interstitial pulmonary diseases	0.000	0.813	0.186
J20.7 Acute bronchitis due to echovirus	0.000	0.816	0.183
J20.6 Acute bronchitis due to rhinovirus	0.000	0.816	0.183
J20.5 Acute bronchitis due to respiratory syncytial virus	0.000	0.816	0.183
J20.4 Acute bronchitis due to parainfluenza virus	0.000	0.816	0.183
J20.3 Acute bronchitis due to coxsackie virus	0.000	0.816	0.183
J20.2 Acute bronchitis due to streptococcus	0.000	0.816	0.183
J20.1 Acute bronchitis due to Haemophilus influenzae	0.000	0.816	0.183
J20.0 Acute bronchitis due to Mycoplasma pneumoniae	0.000	0.816	0.183
F17.1 Harmful use	0.000	0.817	0.183
J20.8 Acute bronchitis due to other specified organisms	0.000	0.818	0.182
J11 Influenza, virus not identified	0.000	0.818	0.182
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.000	0.819	0.181
J17.1 Pneumonia in viral diseases classified elsewhere	0.000	0.822	0.178
J15.0 Pneumonia due to Klebsiella pneumoniae	0.000	0.826	0.174
J00 Acute nasopharyngitis [common cold]	0.000	0.827	0.173
I05.9 Mitral valve disease, unspecified	0.000	0.830	0.170
I95.1 Orthostatic hypotension	0.000	0.830	0.170
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.830	0.169
J18.9 Pneumonia, unspecified	0.000	0.831	0.169
J17.3 Pneumonia in parasitic diseases	0.000	0.832	0.168
Z72.2 Drug use	0.000	0.835	0.165
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.836	0.164
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.000	0.837	0.163
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.837	0.163
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.840	0.160
I97.0 Postcardiotomy syndrome	0.000	0.840	0.160
J20.9 Acute bronchitis, unspecified	0.000	0.841	0.159
I15 Secondary hypertension	0.000	0.841	0.159
J15.1 Pneumonia due to Pseudomonas	0.000	0.842	0.158
J12.9 Viral pneumonia, unspecified	0.000	0.842	0.157
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.843	0.157
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.843	0.157
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.843	0.157
I65.1 Occlusion and stenosis of basilar artery	0.001	0.846	0.154
I13 Hypertensive heart and renal disease	0.000	0.846	0.154
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.847	0.153
I95.8 Other hypotension	0.000	0.847	0.153
Z72.6 Gambling and betting	0.000	0.847	0.152
Z72.5 High-risk sexual behaviour	0.000	0.847	0.152
Z72.3 Lack of physical exercise	0.000	0.847	0.152
Z72.4 Inappropriate diet and eating habits	0.000	0.848	0.152
Z72.8 Other problems related to lifestyle	0.000	0.850	0.150
J17.2 Pneumonia in mycoses	0.000	0.854	0.145
J01 Acute sinusitis	0.000	0.858	0.142
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.859	0.141
F17 Mental and behavioural disorders due to use of tobacco	0.000	0.859	0.141
Z72.9 Problem related to lifestyle, unspecified	0.000	0.861	0.139
I65.2 Occlusion and stenosis of carotid artery	0.000	0.863	0.137
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.865	0.134
F17.2 Dependence syndrome	0.000	0.866	0.134
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.866	0.133
J04 Acute laryngitis and tracheitis	0.000	0.868	0.132
J11.8 Influenza with other manifestations, virus not identified	0.000	0.869	0.130
J47 Bronchiectasis	0.000	0.871	0.129
J45.0 Predominantly allergic asthma	0.000	0.871	0.129
I15.1 Hypertension secondary to other renal disorders	0.000	0.873	0.127
J02 Acute pharyngitis	0.000	0.874	0.126
J03 Acute tonsillitis	0.000	0.874	0.126
I97.1 Other functional disturbances following cardiac surgery	0.000	0.876	0.124
I15.9 Seconday hypertension, unspecified	0.000	0.879	0.121
I87 Other disorders of veins	0.000	0.881	0.119
I11 Hypertensive heart disease	0.000	0.883	0.117
J05.0 Acute obstructive laryngitis [croup]	0.000	0.883	0.117
J05.1 Acute epiglottitis	0.000	0.883	0.117
J81 Pulmonary oedema	0.000	0.883	0.117
I81 Portal vein thrombosis	0.000	0.885	0.114
I95.0 Idiopathic hypotension	0.000	0.886	0.114
I15.8 Other secondary hypertension	0.000	0.886	0.114
I15.2 Hypertension secondary to endocrine disorders	0.000	0.886	0.114
I88 Nonspecific lymphadenitis	0.000	0.886	0.114
I85 Oesophageal varices	0.000	0.889	0.111
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.889	0.110
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.889	0.110
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.889	0.110
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.889	0.110
I12 Hypertensive renal disease	0.000	0.890	0.110
I87.1 Compression of vein	0.000	0.894	0.106
I80 Phlebitis and thrombophlebitis	0.000	0.894	0.106
J11.0 Influenza with pneumonia, virus not identified	0.001	0.896	0.103
J01.0 Acute maxillary sinusitis	0.000	0.897	0.103
J82 Pulmonary eosinophilia, not elsewhere classified	0.002	0.898	0.100
J01.8 Other acute sinusitis	0.000	0.898	0.102
J01.4 Acute pansinusitis	0.000	0.898	0.102
J01.3 Acute sphenoidal sinusitis	0.000	0.898	0.102
J01.1 Acute frontal sinusitis	0.000	0.898	0.102
F17.8 Other mental and behavioural disorders	0.000	0.899	0.101
F17.7 Residual and late-onset psychotic disorder	0.000	0.899	0.101
F17.6 Amnesic syndrome	0.000	0.899	0.101
F17.5 Psychotic disorder	0.000	0.899	0.101
F17.4 Withdrawal state with delirium	0.000	0.899	0.101
F17.3 Withdrawal state	0.000	0.899	0.101
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.901	0.099
I85.0 Oesophageal varices with bleeding	0.000	0.902	0.098
I88.9 Nonspecific lymphadenitis, unspecified	0.000	0.902	0.098
J01.2 Acute ethmoidal sinusitis	0.000	0.903	0.096
F17.9 Unspecified mental and behavioural disorder	0.000	0.903	0.096
I87.8 Other specified disorders of veins	0.000	0.905	0.095
F17.0 Acute intoxication	0.000	0.905	0.095
J04.2 Acute laryngotracheitis	0.000	0.905	0.095
J06 Acute upper respiratory infections of multiple and unspecified sites	0.000	0.906	0.094
J02.0 Streptococcal pharyngitis	0.000	0.906	0.094
J04.1 Acute tracheitis	0.000	0.908	0.092
J02.8 Acute pharyngitis due to other specified organisms	0.000	0.909	0.091
J18.0 Bronchopneumonia, unspecified	0.000	0.909	0.090
J03.8 Acute tonsillitis due to other specified organisms	0.000	0.909	0.090
J03.0 Streptococcal tonsillitis	0.000	0.909	0.090
I15.0 Renovascular hypertension	0.000	0.910	0.090
I63.8 Other cerebral infarction	0.000	0.910	0.090
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.911	0.089
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.913	0.086
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.914	0.086
J01.9 Acute sinusitis, unspecified	0.000	0.914	0.086
I87.9 Disorder of vein, unspecified	0.000	0.914	0.086
I87.0 Postphlebitic syndrome	0.000	0.914	0.086
C34.1 Upper lobe, bronchus or lung	0.000	0.918	0.082
I88.8 Other nonspecific lymphadenitis	0.000	0.918	0.082
I88.1 Chronic lymphadenitis, except mesenteric	0.000	0.918	0.082

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations