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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12441354
log Bayes Factor = 19.2446
Chromosome 15   position 78,821,016  (GRCh37) Explore rs12441354 on Ensembl!
Variant rs12441354 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.000 1.000
J44 Other chronic obstructive pulmonary disease
0.000 0.000 1.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.000 1.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
J43.9 Emphysema, unspecified
0.000 0.000 1.000
I71 Aortic aneurysm and dissection
0.000 0.000 1.000
J43 Emphysema
0.000 0.000 1.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.000 1.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.002 0.998
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.005 0.995
Chapter X Diseases of the respiratory system
0.000 0.005 0.995
I73 Other peripheral vascular diseases
0.000 0.005 0.995
J90-J94 Other diseases of pleura
0.000 0.008 0.992
I70 Atherosclerosis
0.000 0.009 0.991
I73.9 Peripheral vascular disease, unspecified
0.000 0.013 0.987
J92 Pleural plaque
0.000 0.014 0.986
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.014 0.986
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.019 0.981
J42 Unspecified chronic bronchitis
0.000 0.020 0.980
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.027 0.973
I60-I69 Cerebrovascular diseases
0.000 0.028 0.972
Chapter IX Diseases of the circulatory system
0.000 0.031 0.969
J60-J70 Lung diseases due to external agents
0.000 0.032 0.968
J95-J99 Other diseases of the respiratory system
0.000 0.033 0.967
J92.0 Pleural plaque with presence of asbestos
0.000 0.034 0.966
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.039 0.961
I60 Subarachnoid haemorrhage
0.000 0.042 0.958
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.055 0.945
J98 Other respiratory disorders
0.000 0.056 0.944
I77 Other disorders of arteries and arterioles
0.000 0.060 0.940
I67 Other cerebrovascular diseases
0.000 0.061 0.939
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.061 0.939
J98.1 Pulmonary collapse
0.000 0.066 0.934
J92.9 Pleural plaque without asbestos
0.000 0.067 0.933
I69 Sequelae of cerebrovascular disease
0.000 0.072 0.928
I27 Other pulmonary heart diseases
0.000 0.078 0.922
I26 Pulmonary embolism
0.000 0.080 0.920
J90 Pleural effusion, not elsewhere classified
0.000 0.089 0.911
I27.9 Pulmonary heart disease, unspecified
0.000 0.095 0.905
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.095 0.905
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.096 0.904
I67.9 Cerebrovascular disease, unspecified
0.000 0.113 0.887
I73.0 Raynaud's syndrome
0.000 0.119 0.881
I72 Other aneurysm
0.000 0.128 0.872
I69.3 Sequelae of cerebral infarction
0.000 0.129 0.871
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.141 0.859
I77.1 Stricture of artery
0.000 0.147 0.853
J86 Pyothorax
0.000 0.149 0.851
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.154 0.846
J93 Pneumothorax
0.000 0.158 0.842
I60.8 Other subarachnoid haemorrhage
0.000 0.159 0.841
J43.2 Centrilobular emphysema
0.000 0.168 0.832
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.170 0.830
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.171 0.829
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.173 0.827
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.175 0.825
J98.4 Other disorders of lung
0.000 0.176 0.824
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.177 0.823
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.180 0.820
J86.9 Pyothorax without fistula
0.000 0.182 0.818
I67.1 Cerebral aneurysm, nonruptured
0.000 0.188 0.812
I67.8 Other specified cerebrovascular diseases
0.000 0.189 0.811
I77.0 Arteriovenous fistula, acquired
0.000 0.190 0.810
I72.0 Aneurysm of carotid artery
0.000 0.206 0.794
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.207 0.793
I71.0 Dissection of aorta [any part]
0.000 0.215 0.785
J93.1 Other spontaneous pneumothorax
0.000 0.224 0.776
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.229 0.771
I70.0 Atherosclerosis of aorta
0.000 0.234 0.766
J60 Coalworker's pneumoconiosis
0.000 0.235 0.765
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.235 0.765
J98.9 Respiratory disorder, unspecified
0.000 0.236 0.764
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.239 0.761
J64 Unspecified pneumoconiosis
0.000 0.252 0.748
I77.2 Rupture of artery
0.000 0.265 0.735
I61 Intracerebral haemorrhage
0.000 0.272 0.728
I72.8 Aneurysm of other specified arteries
0.000 0.273 0.727
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.717
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.283 0.717
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.283 0.717
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.283 0.717
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.283 0.717
J43.1 Panlobular emphysema
0.000 0.283 0.717
J43.0 MacLeod's syndrome
0.000 0.283 0.717
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.287 0.713
I70.9 Generalised and unspecified atherosclerosis
0.000 0.289 0.711
I70.8 Atherosclerosis of other arteries
0.000 0.289 0.711
I78 Diseases of capillaries
0.000 0.296 0.704
I28 Other diseases of pulmonary vessels
0.000 0.300 0.700
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.303 0.697
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.304 0.696
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.306 0.694
J66 Airway disease due to specific organic dust
0.000 0.306 0.694
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.306 0.694
J62 Pneumoconiosis due to dust containing silica
0.000 0.306 0.694
J65 Pneumoconiosis associated with tuberculosis
0.000 0.306 0.694
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.306 0.693
J96 Respiratory failure, not elsewhere classified
0.000 0.307 0.693
I00-I02 Acute rheumatic fever
0.000 0.308 0.691
J69 Pneumonitis due to solids and liquids
0.000 0.308 0.691
J98.2 Interstitial emphysema
0.000 0.310 0.690
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.313 0.687
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.313 0.687
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.319 0.681
I27.8 Other specified pulmonary heart diseases
0.000 0.321 0.679
J98.3 Compensatory emphysema
0.000 0.323 0.677
I77.5 Necrosis of artery
0.000 0.326 0.674
I77.4 Coeliac artery compression syndrome
0.000 0.326 0.674
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.327 0.673
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.327 0.673
I67.5 Moyamoya disease
0.000 0.327 0.673
I67.4 Hypertensive encephalopathy
0.000 0.327 0.673
I67.3 Progressive vascular leukoencephalopathy
0.000 0.327 0.673
I72.9 Aneurysm of unspecified site
0.000 0.331 0.669
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.333 0.667
I27.1 Kyphoscoliotic heart disease
0.000 0.339 0.661
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.343 0.656
I74 Arterial embolism and thrombosis
0.000 0.351 0.649
J93.0 Spontaneous tension pneumothorax
0.000 0.352 0.648
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.352 0.648
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.356 0.644
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.357 0.643
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.358 0.642
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.359 0.640
J70 Respiratory conditions due to other external agents
0.000 0.361 0.639
J99.1 Respiratory disorders in other diffuse connective tissue disorders
0.000 0.373 0.627
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.375 0.625
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.375 0.625
I72.1 Aneurysm of artery of upper extremity
0.000 0.375 0.625
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.375 0.625
I73.8 Other specified peripheral vascular diseases
0.000 0.375 0.625
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.385 0.615
I27.0 Primary pulmonary hypertension
0.000 0.395 0.605
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.395 0.605
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.399 0.601
J98.6 Disorders of diaphragm
0.000 0.404 0.595
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.406 0.594
I70.1 Atherosclerosis of renal artery
0.000 0.407 0.593
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.410 0.590
I79.1 Aortitis in diseases classified elsewhere
0.000 0.410 0.590
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.410 0.590
J85 Abscess of lung and mediastinum
0.000 0.413 0.587
J99.0 Rheumatoid lung disease
0.000 0.415 0.585
J40 Bronchitis, not specified as acute or chronic
0.000 0.416 0.584
J86.0 Pyothorax with fistula
0.000 0.420 0.580
J43.8 Other emphysema
0.000 0.423 0.577
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.423 0.577
I77.8 Other specified disorders of arteries and arterioles
0.000 0.435 0.565
I72.3 Aneurysm of iliac artery
0.000 0.437 0.563
I67.2 Cerebral atherosclerosis
0.000 0.443 0.557
I77.3 Arterial fibromuscular dysplasia
0.000 0.445 0.555
J94 Other pleural conditions
0.000 0.446 0.554
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.451 0.549
J93.8 Other pneumothorax
0.000 0.451 0.549
J69.8 Pneumonitis due to other solids and liquids
0.000 0.465 0.535
I72.2 Aneurysm of renal artery
0.000 0.466 0.534
I77.6 Arteritis, unspecified
0.000 0.475 0.525
J95.8 Other postprocedural respiratory disorders
0.000 0.478 0.522
I72.4 Aneurysm of artery of lower extremity
0.000 0.478 0.522
I27.2 Other secondary pulmonary hypertension
0.000 0.483 0.517
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.1 Mucopurulent chronic bronchitis
0.000 0.486 0.514
J41.0 Simple chronic bronchitis
0.000 0.486 0.514
I28.8 Other specified diseases of pulmonary vessels
0.000 0.487 0.513
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.490 0.510
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.490 0.510
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.490 0.510
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.490 0.510
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.494 0.506
I78.9 Disease of capillaries, unspecified
0.000 0.495 0.505
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.495 0.504
I62 Other nontraumatic intracranial haemorrhage
0.000 0.498 0.502
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.498 0.502
I28.1 Aneurysm of pulmonary artery
0.000 0.498 0.502
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.498 0.502
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.500 0.500
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.500 0.500
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.500 0.500
I68.0 Cerebral amyloid angiopathy
0.000 0.500 0.500
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.501 0.499
J62.8 Pneumoconiosis due to other dust containing silica
0.000 0.502 0.497
J62.0 Pneumoconiosis due to talc dust
0.000 0.502 0.497
J63.8 Pneumoconiosis due to other specified inorganic dusts
0.000 0.502 0.497
J63.5 Stannosis
0.000 0.502 0.497
J63.4 Siderosis
0.000 0.502 0.497
J63.3 Graphite fibrosis (of lung)
0.000 0.502 0.497
J63.2 Berylliosis
0.000 0.502 0.497
J63.1 Bauxite fibrosis (of lung)
0.000 0.502 0.497
J63.0 Aluminosis (of lung)
0.000 0.502 0.497
J66.8 Airway disease due to other specific organic dusts
0.000 0.502 0.497
J66.2 Cannabinosis
0.000 0.502 0.497
J66.1 Flax-dresser's disease
0.000 0.502 0.497
J66.0 Byssinosis
0.000 0.502 0.497
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours
0.000 0.502 0.497
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.502 0.497
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.502 0.497
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours
0.000 0.502 0.497
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified
0.000 0.502 0.497
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours
0.000 0.502 0.497
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours
0.000 0.502 0.497
J96.9 Respiratory failure, unspecified
0.000 0.503 0.497
J96.1 Chronic respiratory failure
0.000 0.503 0.497
J96.0 Acute respiratory failure
0.000 0.503 0.497
I02 Rheumatic chorea
0.000 0.504 0.496
I01 Rheumatic fever with heart involvement
0.000 0.504 0.496
J69.1 Pneumonitis due to oils and essences
0.000 0.504 0.496
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.506 0.494
I00 Rheumatic fever without mention of heart involvement
0.000 0.507 0.492
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.512 0.487
I78.8 Other diseases of capillaries
0.000 0.516 0.484
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.522 0.478
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.522 0.478
J46 Status asthmaticus
0.000 0.526 0.474
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.526 0.474
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.529 0.471
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.529 0.471
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.529 0.471
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.529 0.471
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.530 0.470
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.530 0.470
J91 Pleural effusion in conditions classified elsewhere
0.000 0.532 0.468
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.534 0.465
J95.5 Postprocedural subglottic stenosis
0.000 0.539 0.461
J95.4 Mendelson's syndrome
0.000 0.539 0.461
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.539 0.461
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.539 0.461
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.539 0.461
J67.8 Hypersensitivity pneumonitis due to other organic dusts
0.000 0.541 0.459
J67.7 Air-conditioner and humidifier lung
0.000 0.541 0.459
J67.6 Maple-bark-stripper's lung
0.000 0.541 0.459
J67.5 Mushroom-worker's lung
0.000 0.541 0.459
J67.4 Maltworker's lung
0.000 0.541 0.459
J67.3 Suberosis
0.000 0.541 0.459
J67.1 Bagassosis
0.000 0.541 0.459
J67.0 Farmer's lung
0.000 0.541 0.459
J70.9 Respiratory conditions due to unspecified external agent
0.000 0.541 0.458
J70.8 Respiratory conditions due to other specified external agents
0.000 0.541 0.458
J70.4 Drug-induced interstitial lung disorder, unspecified
0.000 0.541 0.458
J70.3 Chronic drug-induced interstitial lung disorders
0.000 0.541 0.458
J70.2 Acute drug-induced interstitial lung disorders
0.000 0.541 0.458
J70.0 Acute pulmonary manifestations due to radiation
0.000 0.541 0.458
I74.8 Embolism and thrombosis of other arteries
0.000 0.542 0.458
J93.9 Pneumothorax, unspecified
0.000 0.543 0.457
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.545 0.454
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.546 0.454
I05-I09 Chronic rheumatic heart diseases
0.000 0.546 0.454
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.555 0.445
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust
0.000 0.556 0.444
J69.0 Pneumonitis due to food and vomit
0.000 0.556 0.444
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.565 0.435
J98.8 Other specified respiratory disorders
0.000 0.566 0.434
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.569 0.431
I74.5 Embolism and thrombosis of iliac artery
0.000 0.570 0.430
J98.5 Diseases of mediastinum, not elsewhere classified
0.001 0.571 0.428
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.575 0.425
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.575 0.425
J67.2 Bird fancier's lung
0.000 0.576 0.424
J85.1 Abscess of lung with pneumonia
0.000 0.577 0.422
J85.3 Abscess of mediastinum
0.000 0.579 0.421
J85.0 Gangrene and necrosis of lung
0.000 0.579 0.421
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.583 0.417
J70.1 Chronic and other pulmonary manifestations due to radiation
0.000 0.596 0.404
J09-J18 Influenza and pneumonia
0.000 0.600 0.400
I61.8 Other intracerebral haemorrhage
0.000 0.600 0.399
J94.9 Pleural condition, unspecified
0.000 0.602 0.397
J94.0 Chylous effusion
0.000 0.602 0.397
J94.1 Fibrothorax
0.000 0.603 0.397
J94.8 Other specified pleural conditions
0.000 0.603 0.396
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.606 0.393
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.607 0.393
J20-J22 Other acute lower respiratory infections
0.000 0.609 0.391
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.609 0.390
J95.0 Tracheostomy malfunction
0.000 0.615 0.385
I09 Other rheumatic heart diseases
0.000 0.635 0.365
J85.2 Abscess of lung without pneumonia
0.000 0.641 0.358
J96.09 Acute respiratory failure; Type unspecified
0.000 0.643 0.356
J96.01 Acute respiratory failure; Type II [hypercapnic]
0.000 0.643 0.356
J96.00 Acute respiratory failure; Type I [hypoxic]
0.000 0.643 0.356
J96.19 Chronic respiratory failure; Type unspecified
0.000 0.643 0.356
J96.11 Chronic respiratory failure; Type II [hypercapnic]
0.000 0.643 0.356
J96.10 Chronic respiratory failure; Type I [hypoxic]
0.000 0.643 0.356
J96.99 Respiratory failure, unspecified; Type unspecified
0.000 0.643 0.356
J96.91 Respiratory failure unspecified; Type II [hypercapnic]
0.000 0.643 0.356
J96.90 Respiratory failure, unspecified; Type I [hypoxic]
0.000 0.643 0.356
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.644 0.355
I01.8 Other acute rheumatic heart disease
0.000 0.644 0.355
I01.2 Acute rheumatic myocarditis
0.000 0.644 0.355
I01.1 Acute rheumatic endocarditis
0.000 0.644 0.355
I01.0 Acute rheumatic pericarditis
0.000 0.644 0.355
I02.9 Rheumatic chorea without heart involvement
0.000 0.644 0.355
I02.0 Rheumatic chorea with heart involvement
0.000 0.644 0.355
J80-J84 Other respiratory diseases principally affecting the interstitium
0.001 0.652 0.347
I07 Rheumatic tricuspid valve diseases
0.000 0.662 0.338
I78.1 Naevus, nonneoplastic
0.000 0.669 0.330
I62.1 Nontraumatic extradural haemorrhage
0.000 0.676 0.323
J10 Influenza due to identified influenza virus
0.000 0.686 0.314
J84 Other interstitial pulmonary diseases
0.000 0.687 0.313
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.689 0.311
I70.10 Atherosclerosis of renal artery (without gangrene)
0.001 0.693 0.307
J18 Pneumonia, organism unspecified
0.000 0.696 0.304
I05 Rheumatic mitral valve diseases
0.000 0.696 0.304
I06 Rheumatic aortic valve diseases
0.000 0.699 0.301
I09.9 Rheumatic heart disease, unspecified
0.000 0.699 0.301
J18.1 Lobar pneumonia, unspecified
0.000 0.709 0.291
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.713 0.287
J09 Influenza due to certain identified influenza virus
0.000 0.713 0.287
J45 Asthma
0.000 0.717 0.283
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.720 0.280
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.720 0.280
J21 Acute bronchiolitis
0.000 0.724 0.276
J17 Pneumonia in diseases classified elsewhere
0.000 0.728 0.272
J13 Pneumonia due to Streptococcus pneumoniae
0.000 0.731 0.269
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.735 0.265
I09.8 Other specified rheumatic heart diseases
0.000 0.738 0.262
I09.2 Chronic rheumatic pericarditis
0.000 0.738 0.262
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.738 0.262
I09.0 Rheumatic myocarditis
0.000 0.738 0.262
I63 Cerebral infarction
0.000 0.739 0.261
Z72.1 Alcohol use
0.000 0.740 0.260
Z72.0 Tobacco use
0.000 0.742 0.258
J12 Viral pneumonia, not elsewhere classified
0.000 0.743 0.257
Z72 Problems related to lifestyle
0.000 0.745 0.255
I07.1 Tricuspid insufficiency
0.000 0.745 0.255
J20 Acute bronchitis
0.000 0.746 0.254
I05.1 Rheumatic mitral insufficiency
0.000 0.751 0.249
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.751 0.249
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.754 0.246
J94.2 Haemothorax
0.001 0.756 0.244
J00-J06 Acute upper respiratory infections
0.000 0.756 0.244
I99 Other and unspecified disorders of circulatory system
0.000 0.756 0.243
I07.9 Tricuspid valve disease, unspecified
0.000 0.757 0.243
I07.8 Other tricuspid valve diseases
0.000 0.757 0.243
I07.2 Tricuspid stenosis with insufficiency
0.000 0.757 0.243
I07.0 Tricuspid stenosis
0.000 0.757 0.243
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.000 0.758 0.242
J10.0 Influenza with pneumonia, influenza virus identified
0.000 0.767 0.233
J14 Pneumonia due to Haemophilus influenzae
0.000 0.770 0.230
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.773 0.227
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.773 0.227
J10.8 Influenza with other manifestations, influenza virus identified
0.000 0.775 0.225
J84.0 Alveolar and parietoalveolar conditions
0.000 0.775 0.224
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.776 0.224
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.777 0.223
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.777 0.223
J84.8 Other specified interstitial pulmonary diseases
0.000 0.778 0.221
J18.2 Hypostatic pneumonia, unspecified
0.000 0.782 0.218
I05.8 Other mitral valve diseases
0.000 0.782 0.218
I05.0 Mitral stenosis
0.000 0.782 0.218
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.784 0.216
I06.8 Other rheumatic aortic valve diseases
0.000 0.784 0.216
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.784 0.216
I06.1 Rheumatic aortic insufficiency
0.000 0.784 0.216
I10-I15 Hypertensive diseases
0.000 0.788 0.212
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.794 0.206
J16.8 Pneumonia due to other specified infectious organisms
0.000 0.794 0.206
J16.0 Chlamydial pneumonia
0.000 0.794 0.206
J15.2 Pneumonia due to staphylococcus
0.000 0.796 0.204
Z72.2 Drug use
0.000 0.796 0.204
J45.8 Mixed asthma
0.000 0.797 0.203
J45.1 Nonallergic asthma
0.000 0.797 0.203
J15.8 Other bacterial pneumonia
0.000 0.798 0.202
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.799 0.201
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.799 0.201
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.799 0.201
I98.0 Cardiovascular syphilis
0.000 0.799 0.201
J15.5 Pneumonia due to Escherichia coli
0.000 0.800 0.200
J18.8 Other pneumonia, organism unspecified
0.000 0.802 0.198
J21.8 Acute bronchiolitis due to other specified organisms
0.000 0.802 0.198
J21.1 Acute bronchiolitis due to human metapneumovirus
0.000 0.802 0.198
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.000 0.802 0.198
I05.2 Mitral stenosis with insufficiency
0.000 0.802 0.198
J17.8 Pneumonia in other diseases classified elsewhere
0.000 0.805 0.195
J15.4 Pneumonia due to other streptococci
0.000 0.805 0.195
J21.9 Acute bronchiolitis, unspecified
0.000 0.806 0.193
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.000 0.806 0.193
I06.0 Rheumatic aortic stenosis
0.000 0.809 0.191
J15.3 Pneumonia due to streptococcus, group B
0.000 0.809 0.190
I95 Hypotension
0.000 0.810 0.190
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.810 0.189
J15.9 Bacterial pneumonia, unspecified
0.000 0.812 0.188
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.813 0.187
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.813 0.187
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.813 0.187
J00 Acute nasopharyngitis [common cold]
0.000 0.815 0.185
J12.8 Other viral pneumonia
0.000 0.816 0.184
J12.3 Human metapneumovirus pneumonia
0.000 0.816 0.184
J12.2 Parainfluenza virus pneumonia
0.000 0.816 0.184
J12.1 Respiratory syncytial virus pneumonia
0.000 0.816 0.184
J12.0 Adenoviral pneumonia
0.000 0.816 0.184
Z72.6 Gambling and betting
0.000 0.817 0.183
Z72.5 High-risk sexual behaviour
0.000 0.817 0.183
Z72.3 Lack of physical exercise
0.000 0.817 0.183
Z72.4 Inappropriate diet and eating habits
0.000 0.817 0.183
J20.7 Acute bronchitis due to echovirus
0.000 0.817 0.182
J20.6 Acute bronchitis due to rhinovirus
0.000 0.817 0.182
J20.5 Acute bronchitis due to respiratory syncytial virus
0.000 0.817 0.182
J20.4 Acute bronchitis due to parainfluenza virus
0.000 0.817 0.182
J20.3 Acute bronchitis due to coxsackie virus
0.000 0.817 0.182
J20.2 Acute bronchitis due to streptococcus
0.000 0.817 0.182
J20.1 Acute bronchitis due to Haemophilus influenzae
0.000 0.817 0.182
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.000 0.817 0.182
J20.8 Acute bronchitis due to other specified organisms
0.000 0.819 0.181
Z72.8 Other problems related to lifestyle
0.000 0.819 0.180
J11 Influenza, virus not identified
0.000 0.822 0.178
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.000 0.824 0.176
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.825 0.175
J17.1 Pneumonia in viral diseases classified elsewhere
0.000 0.826 0.173
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.828 0.172
J15.0 Pneumonia due to Klebsiella pneumoniae
0.000 0.831 0.169
I95.1 Orthostatic hypotension
0.000 0.832 0.167
I05.9 Mitral valve disease, unspecified
0.000 0.833 0.167
Z72.9 Problem related to lifestyle, unspecified
0.000 0.833 0.167
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.834 0.166
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.835 0.165
J17.3 Pneumonia in parasitic diseases
0.000 0.836 0.164
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.837 0.163
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.837 0.163
I97.0 Postcardiotomy syndrome
0.000 0.837 0.163
J18.9 Pneumonia, unspecified
0.000 0.838 0.162
F17.1 Harmful use
0.000 0.838 0.162
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.840 0.160
J20.9 Acute bronchitis, unspecified
0.000 0.842 0.158
I15 Secondary hypertension
0.000 0.843 0.157
J12.9 Viral pneumonia, unspecified
0.000 0.846 0.154
J15.1 Pneumonia due to Pseudomonas
0.000 0.846 0.154
I65.1 Occlusion and stenosis of basilar artery
0.001 0.847 0.152
I13 Hypertensive heart and renal disease
0.000 0.847 0.152
J01 Acute sinusitis
0.000 0.848 0.152
I95.8 Other hypotension
0.000 0.848 0.152
J02 Acute pharyngitis
0.000 0.854 0.146
J17.2 Pneumonia in mycoses
0.000 0.858 0.142
J04 Acute laryngitis and tracheitis
0.000 0.858 0.142
J03 Acute tonsillitis
0.000 0.863 0.137
J45.0 Predominantly allergic asthma
0.000 0.863 0.137
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.863 0.137
I87 Other disorders of veins
0.000 0.863 0.137
I65.2 Occlusion and stenosis of carotid artery
0.000 0.866 0.134
J81 Pulmonary oedema
0.000 0.866 0.133
J47 Bronchiectasis
0.000 0.870 0.130
I81 Portal vein thrombosis
0.000 0.871 0.129
I88 Nonspecific lymphadenitis
0.000 0.871 0.128
J11.8 Influenza with other manifestations, virus not identified
0.000 0.872 0.127
F17 Mental and behavioural disorders due to use of tobacco
0.000 0.873 0.127
I85 Oesophageal varices
0.000 0.873 0.127
I97.1 Other functional disturbances following cardiac surgery
0.000 0.873 0.126
J05.0 Acute obstructive laryngitis [croup]
0.000 0.874 0.126
I15.1 Hypertension secondary to other renal disorders
0.000 0.874 0.126
J05.1 Acute epiglottitis
0.000 0.874 0.126
F17.2 Dependence syndrome
0.000 0.878 0.122
I87.1 Compression of vein
0.000 0.879 0.121
I80 Phlebitis and thrombophlebitis
0.000 0.880 0.120
I15.9 Seconday hypertension, unspecified
0.000 0.880 0.120
J82 Pulmonary eosinophilia, not elsewhere classified
0.002 0.882 0.116
I11 Hypertensive heart disease
0.000 0.884 0.116
I95.0 Idiopathic hypotension
0.000 0.887 0.113
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.887 0.113
I15.8 Other secondary hypertension
0.000 0.887 0.112
I15.2 Hypertension secondary to endocrine disorders
0.000 0.887 0.112
J02.8 Acute pharyngitis due to other specified organisms
0.000 0.888 0.112
I85.0 Oesophageal varices with bleeding
0.000 0.889 0.111
J01.0 Acute maxillary sinusitis
0.000 0.889 0.110
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.890 0.110
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.890 0.109
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.890 0.109
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.890 0.109
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.890 0.109
I87.8 Other specified disorders of veins
0.000 0.891 0.109
J01.8 Other acute sinusitis
0.000 0.891 0.109
J01.4 Acute pansinusitis
0.000 0.891 0.109
J01.3 Acute sphenoidal sinusitis
0.000 0.891 0.109
J01.1 Acute frontal sinusitis
0.000 0.891 0.109
J02.0 Streptococcal pharyngitis
0.000 0.891 0.109
I12 Hypertensive renal disease
0.000 0.893 0.107
I63.8 Other cerebral infarction
0.000 0.894 0.106
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.894 0.105
J01.2 Acute ethmoidal sinusitis
0.000 0.896 0.103
J04.2 Acute laryngotracheitis
0.000 0.898 0.102
J11.0 Influenza with pneumonia, virus not identified
0.001 0.899 0.101
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.899 0.101
J18.0 Bronchopneumonia, unspecified
0.000 0.900 0.100
J03.8 Acute tonsillitis due to other specified organisms
0.000 0.901 0.099
J03.0 Streptococcal tonsillitis
0.000 0.901 0.099
I87.9 Disorder of vein, unspecified
0.000 0.902 0.098
I87.0 Postphlebitic syndrome
0.000 0.902 0.098
J04.1 Acute tracheitis
0.000 0.902 0.098
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.902 0.098
I88.8 Other nonspecific lymphadenitis
0.000 0.908 0.092
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.908 0.092
J01.9 Acute sinusitis, unspecified
0.000 0.908 0.092
J80 Adult respiratory distress syndrome
0.002 0.908 0.090
F17.8 Other mental and behavioural disorders
0.000 0.909 0.091
F17.7 Residual and late-onset psychotic disorder
0.000 0.909 0.091
F17.6 Amnesic syndrome
0.000 0.909 0.091
F17.5 Psychotic disorder
0.000 0.909 0.091
F17.4 Withdrawal state with delirium
0.000 0.909 0.091
F17.3 Withdrawal state
0.000 0.909 0.091
Z50.1 Other physical therapy
0.000 0.909 0.091
Z70-Z76 Persons encountering health services in other circumstances
0.000 0.909 0.091
I15.0 Renovascular hypertension
0.000 0.911 0.089
Z50 Care involving use of rehabilitation procedures
0.000 0.911 0.089

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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