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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1247318
log Bayes Factor = 0.713943
Chromosome 6   position 161,333,937  (GRCh37) Explore rs1247318 on Ensembl!
Variant rs1247318 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M20-M25 Other joint disorders
0.572 0.428 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.570 0.430 0.000
M80-M85 Disorders of bone density and structure
0.569 0.431 0.000
M21 Other acquired deformities of limbs
0.567 0.433 0.000
M85 Other disorders of bone density and structure
0.563 0.437 0.000
M05-M14 Inflammatory polyarthropathies
0.547 0.453 0.000
M84 Disorders of continuity of bone
0.542 0.458 0.000
M22 Disorders of patella
0.534 0.466 0.000
M33 Dermatopolymyositis
0.532 0.468 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.531 0.469 0.000
M85.8 Other specified disorders of bone density and structure
0.527 0.473 0.000
M85.6 Other cyst of bone
0.520 0.480 0.000
M07 Psoriatic and enteropathic arthropathies
0.515 0.485 0.000
M21.6 Other acquired deformities of ankle and foot
0.507 0.493 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.505 0.495 0.000
M34 Systemic sclerosis
0.505 0.495 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.502 0.498 0.000
M22.2 Patellofemoral disorders
0.499 0.501 0.000
M07.3 Other psoriatic arthropathies
0.493 0.507 0.000
M32 Systemic lupus erythematosus
0.490 0.510 0.000
M11 Other crystal arthropathies
0.489 0.510 0.000
M21.1 Varus deformity, not elsewhere classified
0.489 0.511 0.000
M21.4 Flat foot [pes planus] (acquired)
0.485 0.515 0.000
M21.2 Flexion deformity
0.484 0.516 0.000
M33.2 Polymyositis
0.477 0.523 0.000
M21.3 Wrist or foot drop (acquired)
0.476 0.524 0.000
M24 Other specific joint derangements
0.475 0.525 0.000
M13 Other arthritis
0.475 0.525 0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot
0.464 0.536 0.000
M85.0 Fibrous dysplasia (monostotic)
0.463 0.537 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.462 0.538 0.000
M15-M19 Arthrosis
0.461 0.539 0.000
M60-M63 Disorders of muscles
0.459 0.541 0.000
M21.7 Unequal limb length (acquired)
0.456 0.544 0.000
M33.1 Other dermatomyositis
0.454 0.546 0.000
M85.68 Other cyst of bone (Other)
0.451 0.549 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.450 0.550 0.000
M11.2 Other chondrocalcinosis
0.448 0.552 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.446 0.553 0.000
M22.8 Other disorders of patella
0.446 0.554 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.444 0.556 0.000
M19 Other arthrosis
0.444 0.556 0.000
M10 Gout
0.442 0.558 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.441 0.559 0.000
M34.9 Systemic sclerosis, unspecified
0.437 0.562 0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)
0.436 0.564 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.436 0.564 0.000
M15 Polyarthrosis
0.434 0.566 0.000
M13.94 Arthritis, unspecified (Hand)
0.434 0.566 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.431 0.569 0.000
M00-M03 Infectious arthropathies
0.431 0.569 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.430 0.570 0.000
M34.1 CR(E)ST syndrome
0.428 0.572 0.000
M82 Osteoporosis in diseases classified elsewhere
0.428 0.572 0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot
0.427 0.573 0.000
M86-M90 Other osteopathies
0.427 0.573 0.000
M19.1 Posttraumatic arthrosis of other joints
0.423 0.577 0.000
M85.64 Other cyst of bone (Hand)
0.423 0.577 0.000
M21.26 Flexion deformity (Lower leg)
0.423 0.577 0.000
M13.9 Arthritis, unspecified
0.421 0.579 0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)
0.420 0.579 0.000
M85.2 Hyperostosis of skull
0.420 0.580 0.000
K60.2 Anal fissure, unspecified
0.420 0.580 0.000
M24.2 Disorder of ligament
0.420 0.580 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.419 0.581 0.000
M19.0 Primary arthrosis of other joints
0.419 0.581 0.000
M21.8 Other specified acquired deformities of limbs
0.418 0.581 0.000
M85.88 Other specified disorders of bone density and structure (Other)
0.417 0.583 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.411 0.589 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.410 0.590 0.000
M24.1 Other articular cartilage disorders
0.409 0.591 0.000
M07.38 Other psoriatic arthropathies (Other)
0.409 0.591 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.409 0.591 0.000
M84.4 Pathological fracture, not elsewhere classified
0.409 0.591 0.000
M83 Adult osteomalacia
0.408 0.592 0.000
M45-M49 Spondylopathies
0.407 0.593 0.000
M40-M43 Deforming dorsopathies
0.407 0.593 0.000
M21.9 Acquired deformity of limb, unspecified
0.406 0.594 0.000
M12 Other specific arthropathies
0.404 0.595 0.000
M85.65 Other cyst of bone (Pelvic region and thigh)
0.404 0.596 0.000
M85.9 Disorder of bone density and structure, unspecified
0.404 0.596 0.000
M85.5 Aneurysmal bone cyst
0.404 0.596 0.000
M85.4 Solitary bone cyst
0.404 0.596 0.000
M85.3 Osteitis condensans
0.404 0.596 0.000
M85.1 Skeletal fluorosis
0.404 0.596 0.000
K60 Fissure and fistula of anal and rectal regions
0.403 0.597 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.400 0.600 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.397 0.603 0.000
M85.67 Other cyst of bone (Ankle and foot)
0.395 0.605 0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)
0.394 0.606 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.392 0.608 0.000
M08 Juvenile arthritis
0.392 0.608 0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)
0.392 0.608 0.000
M65-M68 Disorders of synovium and tendon
0.390 0.610 0.000
M22.0 Recurrent dislocation of patella
0.390 0.610 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.390 0.610 0.000
K60.3 Anal fistula
0.389 0.611 0.000
M84.9 Disorder of continuity of bone, unspecified
0.389 0.611 0.000
M84.8 Other disorders of continuity of bone
0.389 0.611 0.000
M84.3 Stress fracture, not elsewhere classified
0.389 0.611 0.000
M84.2 Delayed union of fracture
0.389 0.611 0.000
M21.25 Flexion deformity (Pelvic region and thigh)
0.389 0.611 0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.388 0.612 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.387 0.613 0.000
M30 Polyarteritis nodosa and related conditions
0.386 0.614 0.000
M24.5 Contracture of joint
0.384 0.616 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.384 0.616 0.000
M22.1 Recurrent subluxation of patella
0.383 0.617 0.000
M22.9 Disorder of patella, unspecified
0.383 0.617 0.000
M62 Other disorders of muscle
0.382 0.618 0.000
M33.9 Dermatopolymyositis, unspecified
0.382 0.618 0.000
M33.0 Juvenile dermatomyositis
0.382 0.618 0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)
0.381 0.619 0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)
0.381 0.619 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.379 0.621 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.379 0.621 0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)
0.378 0.622 0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)
0.378 0.622 0.000
M85.84 Other specified disorders of bone density and structure (Hand)
0.378 0.622 0.000
M85.83 Other specified disorders of bone density and structure (Forearm)
0.378 0.622 0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)
0.378 0.622 0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)
0.378 0.622 0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)
0.377 0.623 0.000
M15.1 Heberden's nodes (with arthropathy)
0.376 0.624 0.000
M91-M94 Chondropathies
0.375 0.625 0.000
M81 Osteoporosis without pathological fracture
0.373 0.627 0.000
M85.69 Other cyst of bone (Site unspecified)
0.373 0.627 0.000
M85.66 Other cyst of bone (Lower leg)
0.373 0.627 0.000
M85.63 Other cyst of bone (Forearm)
0.373 0.627 0.000
M85.62 Other cyst of bone (Upper arm)
0.373 0.627 0.000
M85.61 Other cyst of bone (Shoulder region)
0.373 0.627 0.000
M85.60 Other cyst of bone (Multiple sites)
0.373 0.627 0.000
M13.93 Arthritis, unspecified (Forearm)
0.371 0.629 0.000
M07.6 Other enteropathic arthropathies
0.369 0.630 0.000
M07.5 Arthropathy in ulcerative colitis
0.369 0.630 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.369 0.630 0.000
M07.2 Psoriatic spondylitis
0.369 0.630 0.000
M07.1 Arthritis mutilans
0.369 0.630 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.369 0.630 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.369 0.631 0.000
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)
0.368 0.632 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.368 0.632 0.000
M24.24 Disorder of ligament (Hand)
0.367 0.633 0.000
K60.1 Chronic anal fissure
0.366 0.634 0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec
0.363 0.636 0.000
M21.68 Other acquired deformities of ankle and foot-Other
0.363 0.636 0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg
0.363 0.636 0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh
0.363 0.636 0.000
M21.64 Other acquired deformities of ankle and foot-Hand
0.363 0.636 0.000
M21.63 Other acquired deformities of ankle and foot-Forearm
0.363 0.636 0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm
0.363 0.636 0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region
0.363 0.636 0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites
0.363 0.636 0.000
M99 Biomechanical lesions, not elsewhere classified
0.363 0.637 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.362 0.638 0.000
M34.0 Progressive systemic sclerosis
0.362 0.638 0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)
0.360 0.640 0.000
M14 Arthropathies in other diseases classified elsewhere
0.358 0.641 0.000
M22.4 Chondromalacia patellae
0.358 0.642 0.000
M10.9 Gout, unspecified
0.358 0.642 0.000
M20 Acquired deformities of fingers and toes
0.356 0.644 0.000
M15.8 Other polyarthrosis
0.356 0.644 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.353 0.647 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.353 0.647 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.353 0.647 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.353 0.647 0.000
M90 Osteopathies in diseases classified elsewhere
0.352 0.648 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.351 0.649 0.000
M32.8 Other forms of systemic lupus erythematosus
0.351 0.649 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.351 0.649 0.000
M11.9 Crystal arthropathy, unspecified
0.351 0.649 0.000
M11.8 Other specified crystal arthropathies
0.351 0.649 0.000
M11.1 Familial chondrocalcinosis
0.351 0.649 0.000
M11.0 Hydroxyapatite deposition disease
0.351 0.649 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.351 0.649 0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)
0.351 0.649 0.000
M21.18 Varus deformity, not elsewhere classified (Other)
0.351 0.649 0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)
0.351 0.649 0.000
M21.14 Varus deformity, not elsewhere classified (Hand)
0.351 0.649 0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)
0.351 0.649 0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)
0.351 0.649 0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)
0.351 0.649 0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)
0.351 0.649 0.000
M13.0 Polyarthritis, unspecified
0.351 0.649 0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)
0.351 0.649 0.000
M40 Kyphosis and lordosis
0.350 0.649 0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec
0.348 0.652 0.000
M21.48 Flat foot [pes planus] (acquired)-Other
0.348 0.652 0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg
0.348 0.652 0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh
0.348 0.652 0.000
M21.44 Flat foot [pes planus] (acquired)-Hand
0.348 0.652 0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm
0.348 0.652 0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm
0.348 0.652 0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region
0.348 0.652 0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites
0.348 0.652 0.000
M22.3 Other derangements of patella
0.348 0.652 0.000
M21.29 Flexion deformity (Site unspecified)
0.347 0.653 0.000
M21.28 Flexion deformity (Other)
0.347 0.653 0.000
M21.23 Flexion deformity (Forearm)
0.347 0.653 0.000
M21.22 Flexion deformity (Upper arm)
0.347 0.653 0.000
M21.21 Flexion deformity (Shoulder region)
0.347 0.653 0.000
M21.20 Flexion deformity (Multiple sites)
0.347 0.653 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.346 0.654 0.000
M13.8 Other specified arthritis
0.346 0.654 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.346 0.654 0.000
M24.26 Disorder of ligament (Lower leg)
0.345 0.655 0.000
M24.7 Protrusio acetabuli
0.345 0.655 0.000
M20.5 Other deformities of toe(s) (acquired)
0.343 0.657 0.000
M21.39 Wrist or foot drop (acquired)-Site unspec
0.341 0.658 0.000
M21.38 Wrist or foot drop (acquired)-Other
0.341 0.658 0.000
M21.36 Wrist or foot drop (acquired)-Lower leg
0.341 0.658 0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh
0.341 0.658 0.000
M21.34 Wrist or foot drop (acquired) (Hand)
0.341 0.658 0.000
M21.33 Wrist or foot drop (acquired) (Forearm)
0.341 0.658 0.000
M21.32 Wrist or foot drop (acquired)-Upper arm
0.341 0.658 0.000
M21.31 Wrist or foot drop (acquired)-Shldr region
0.341 0.658 0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)
0.341 0.658 0.000
M24.9 Joint derangement, unspecified
0.341 0.659 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.340 0.660 0.000
M19.09 Primary arthrosis of other joints (Site unspecified)
0.339 0.661 0.000
M19.13 Post-traumatic arthrosis of other joints (Forearm)
0.339 0.661 0.000
M24.56 Contracture of joint (Lower leg)
0.339 0.661 0.000
K60.5 Anorectal fistula
0.337 0.663 0.000
M19.14 Post-traumatic arthrosis of other joints (Hand)
0.335 0.664 0.000
M24.23 Disorder of ligament (Forearm)
0.334 0.666 0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)
0.332 0.668 0.000
M85.08 Fibrous dysplasia (monostotic) (Other)
0.332 0.668 0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)
0.332 0.668 0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)
0.332 0.668 0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)
0.332 0.668 0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)
0.332 0.668 0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)
0.332 0.668 0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)
0.332 0.668 0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)
0.332 0.668 0.000
M15.4 Erosive (osteo)arthrosis
0.331 0.669 0.000
M00 Pyogenic arthritis
0.331 0.669 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.329 0.671 0.000
M61 Calcification and ossification of muscle
0.329 0.671 0.000
M13.1 Monoarthritis, not elsewhere classified
0.329 0.671 0.000
M10.0 Idiopathic gout
0.329 0.671 0.000
M49 Spondylopathies in diseases classified elsewhere
0.328 0.672 0.000
M21.79 Unequal limb length (acquired) (Site unspecified)
0.327 0.673 0.000
M21.78 Unequal limb length (acquired)-Other
0.327 0.673 0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)
0.327 0.673 0.000
M21.76 Unequal limb length (acquired) (Lower leg)
0.327 0.673 0.000
M21.74 Unequal limb length (acquired) (Hand)
0.327 0.673 0.000
M21.73 Unequal limb length (acquired) (Forearm)
0.327 0.673 0.000
M21.72 Unequal limb length (acquired) (Upper arm)
0.327 0.673 0.000
M21.71 Unequal limb length (acquired)-Shldr region
0.327 0.673 0.000
M21.70 Unequal limb length (acquired) (Multiple sites)
0.327 0.673 0.000
M82.1 Osteoporosis in endocrine disorders
0.327 0.673 0.000
M19.02 Primary arthrosis of other joints (Upper arm)
0.327 0.673 0.000
M21.24 Flexion deformity (Hand)
0.327 0.673 0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)
0.327 0.673 0.000
M19.2 Other secondary arthrosis
0.327 0.673 0.000
M60 Myositis
0.326 0.674 0.000
M67 Other disorders of synovium and tendon
0.326 0.674 0.000
M15.3 Secondary multiple arthrosis
0.324 0.676 0.000
M23 Internal derangement of knee
0.323 0.677 0.000
M11.29 Other chondrocalcinosis (Site unspecified)
0.322 0.678 0.000
M11.28 Other chondrocalcinosis (Other)
0.322 0.678 0.000
M11.27 Other chondrocalcinosis (Ankle and foot)
0.322 0.678 0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)
0.322 0.678 0.000
M11.24 Other chondrocalcinosis (Hand)
0.322 0.678 0.000
M11.23 Other chondrocalcinosis (Forearm)
0.322 0.678 0.000
M11.22 Other chondrocalcinosis (Upper arm)
0.322 0.678 0.000
M11.21 Other chondrocalcinosis (Shoulder region)
0.322 0.678 0.000
M11.20 Other chondrocalcinosis (Multiple sites)
0.322 0.678 0.000
M21.27 Flexion deformity (Ankle and foot)
0.321 0.679 0.000
M24.6 Ankylosis of joint
0.320 0.680 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.319 0.680 0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.318 0.681 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.318 0.681 0.000
M96.5 Postradiation scoliosis
0.318 0.681 0.000
M96.4 Postsurgical lordosis
0.318 0.681 0.000
M96.3 Postlaminectomy kyphosis
0.318 0.681 0.000
M96.2 Postradiation kyphosis
0.318 0.681 0.000
M19.8 Other specified arthrosis
0.318 0.682 0.000
M85.20 Hyperostosis of skull-Mult sites
0.317 0.683 0.000
M10.4 Other secondary gout
0.317 0.683 0.000
M10.3 Gout due to impairment of renal function
0.317 0.683 0.000
M10.2 Drug-induced gout
0.317 0.683 0.000
M10.1 Lead-induced gout
0.317 0.683 0.000
M89 Other disorders of bone
0.317 0.683 0.000
M05 Seropositive rheumatoid arthritis
0.316 0.683 0.000
M34.8 Other forms of systemic sclerosis
0.316 0.684 0.000
M46 Other inflammatory spondylopathies
0.316 0.684 0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)
0.312 0.688 0.000
M62.6 Muscle strain
0.312 0.688 0.000
M15.9 Polyarthrosis, unspecified
0.311 0.689 0.000
M15.0 Primary generalised (osteo)arthrosis
0.311 0.689 0.000
M21.0 Valgus deformity, not elsewhere classified
0.311 0.689 0.000
M81.4 Drug-induced osteoporosis
0.310 0.690 0.000
M86 Osteomyelitis
0.310 0.690 0.000
M40.2 Other and unspecified kyphosis
0.310 0.690 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.309 0.691 0.000
M02 Reactive arthropathies
0.309 0.691 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.309 0.691 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.307 0.693 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.307 0.693 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.307 0.693 0.000
M12.2 Villonodular synovitis (pigmented)
0.306 0.694 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.306 0.694 0.000
M48 Other spondylopathies
0.305 0.695 0.000
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)
0.303 0.696 0.000
M19.18 Post-traumatic arthrosis of other joints (Other)
0.303 0.696 0.000
M19.16 Post-traumatic arthrosis of other joints-Lower leg
0.303 0.696 0.000
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)
0.303 0.696 0.000
M19.12 Post-traumatic arthrosis of other joints (Upper arm)
0.303 0.696 0.000
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)
0.303 0.696 0.000
M31 Other necrotising vasculopathies
0.303 0.696 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.302 0.698 0.000
M85.29 Hyperostosis of skull-Site unspec
0.301 0.699 0.000
M85.28 Hyperostosis of skull-Other
0.301 0.699 0.000
M85.27 Hyperostosis of skull-Ankle/Foot
0.301 0.699 0.000
M85.26 Hyperostosis of skull-Lower Leg
0.301 0.699 0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh
0.301 0.699 0.000
M85.24 Hyperostosis of skull-Hand
0.301 0.699 0.000
M85.23 Hyperostosis of skull-Forearm
0.301 0.699 0.000
M85.22 Hyperostosis of skull-Upper arm
0.301 0.699 0.000
M85.21 Hyperostosis of skull-Shldr region
0.301 0.699 0.000
M24.29 Disorder of ligament (Site unspecified)
0.301 0.699 0.000
M24.28 Disorder of ligament (Other)
0.301 0.699 0.000
M24.25 Disorder of ligament (Pelvic region and thigh)
0.301 0.699 0.000
M24.22 Disorder of ligament (Upper arm)
0.301 0.699 0.000
M24.21 Disorder of ligament (Shoulder region)
0.301 0.699 0.000
M24.20 Disorder of ligament (Multiple sites)
0.301 0.699 0.000
K60.0 Acute anal fissure
0.300 0.700 0.000
M81.2 Osteoporosis of disuse
0.300 0.700 0.000
M19.08 Primary arthrosis of other joints (Other)
0.300 0.700 0.000
M19.06 Primary arthrosis of other joints-Lower leg
0.300 0.700 0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)
0.300 0.700 0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)
0.300 0.700 0.000
M21.88 Other specified acquired deformities of limbs-Other
0.300 0.700 0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)
0.300 0.700 0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)
0.300 0.700 0.000
M21.84 Other specified acquired deformities of limbs (Hand)
0.300 0.700 0.000
M21.83 Other specified acquired deformities of limbs (Forearm)
0.300 0.700 0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)
0.300 0.700 0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)
0.300 0.700 0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)
0.300 0.700 0.000
M23.8 Other internal derangements of knee
0.299 0.701 0.000
M10.90 Gout, unspecified (Multiple sites)
0.298 0.702 0.000
M20.4 Other hammer toe(s) (acquired)
0.296 0.704 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.296 0.704 0.000
M95.0 Acquired deformity of nose
0.296 0.704 0.000
M67.1 Other contracture of tendon (sheath)
0.295 0.705 0.000
M10.96 Gout, unspecified (Lower leg)
0.294 0.706 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.294 0.706 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.294 0.706 0.000
M36.3 Arthropathy in other blood disorders
0.294 0.706 0.000
M36.2 Haemophilic arthropathy
0.294 0.706 0.000
M36.1 Arthropathy in neoplastic disease
0.294 0.706 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.294 0.706 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.294 0.706 0.000
M87 Osteonecrosis
0.294 0.706 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.294 0.706 0.000
M24.18 Other articular cartilage disorders (Other)
0.294 0.706 0.000
M24.14 Other articular cartilage disorders (Hand)
0.294 0.706 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.294 0.706 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.294 0.706 0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)
0.293 0.707 0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)
0.293 0.707 0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)
0.293 0.707 0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)
0.293 0.707 0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)
0.293 0.707 0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)
0.293 0.707 0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)
0.293 0.707 0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)
0.293 0.707 0.000
M83.9 Adult osteomalacia, unspecified
0.293 0.707 0.000
M83.8 Other adult osteomalacia
0.293 0.707 0.000
M83.5 Other drug-induced osteomalacia in adults
0.293 0.707 0.000
M83.4 Aluminum bone disease
0.293 0.707 0.000
M83.3 Adult osteomalacia due to malnutrition
0.293 0.707 0.000
M83.2 Adult osteomalacia due to malabsorption
0.293 0.707 0.000
M83.1 Senile osteomalacia
0.293 0.707 0.000
M83.0 Puerperal osteomalacia
0.293 0.707 0.000
M24.51 Contracture of joint (Shoulder region)
0.292 0.708 0.000
M30.0 Polyarteritis nodosa
0.292 0.708 0.000
M42 Spinal osteochondrosis
0.292 0.708 0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)
0.291 0.708 0.000
M21.98 Acquired deformity of limb, unspecified-Other
0.291 0.708 0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)
0.291 0.708 0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)
0.291 0.708 0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)
0.291 0.708 0.000
M21.94 Acquired deformity of limb, unspecified (Hand)
0.291 0.708 0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)
0.291 0.708 0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)
0.291 0.708 0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)
0.291 0.708 0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)
0.291 0.708 0.000
M90.7 Fracture of bone in neoplastic disease
0.290 0.709 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.290 0.710 0.000
M12.5 Traumatic arthropathy
0.290 0.710 0.000
M12.4 Intermittent hydrarthrosis
0.290 0.710 0.000
M12.1 Kaschin-Beck disease
0.290 0.710 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.290 0.710 0.000
M85.19 Skeletal fluorosis (Site unspecified)
0.290 0.710 0.000
M85.18 Skeletal fluorosis (Other)
0.290 0.710 0.000
M85.17 Skeletal fluorosis (Ankle and foot)
0.290 0.710 0.000
M85.16 Skeletal fluorosis (Lower leg)
0.290 0.710 0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)
0.290 0.710 0.000
M85.14 Skeletal fluorosis (Hand)
0.290 0.710 0.000
M85.13 Skeletal fluorosis (Forearm)
0.290 0.710 0.000
M85.12 Skeletal fluorosis (Upper arm)
0.290 0.710 0.000
M85.11 Skeletal fluorosis (Shoulder region)
0.290 0.710 0.000
M85.10 Skeletal fluorosis (Multiple sites)
0.290 0.710 0.000
M85.39 Osteitis condensans (Site unspecified)
0.290 0.710 0.000
M85.38 Osteitis condensans (Other)
0.290 0.710 0.000
M85.37 Osteitis condensans (Ankle and foot)
0.290 0.710 0.000
M85.36 Osteitis condensans (Lower leg)
0.290 0.710 0.000
M85.35 Osteitis condensans (Pelvic region and thigh)
0.290 0.710 0.000
M85.34 Osteitis condensans (Hand)
0.290 0.710 0.000
M85.33 Osteitis condensans (Forearm)
0.290 0.710 0.000
M85.32 Osteitis condensans (Upper arm)
0.290 0.710 0.000
M85.31 Osteitis condensans (Shoulder region)
0.290 0.710 0.000
M85.30 Osteitis condensans (Multiple sites)
0.290 0.710 0.000
M85.49 Solitary bone cyst (Site unspecified)
0.290 0.710 0.000
M85.48 Solitary bone cyst (Other)
0.290 0.710 0.000
M85.47 Solitary bone cyst (Ankle and foot)
0.290 0.710 0.000
M85.46 Solitary bone cyst (Lower leg)
0.290 0.710 0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)
0.290 0.710 0.000
M85.44 Solitary bone cyst (Hand)
0.290 0.710 0.000
M85.43 Solitary bone cyst (Forearm)
0.290 0.710 0.000
M85.42 Solitary bone cyst (Upper arm)
0.290 0.710 0.000
M85.41 Solitary bone cyst (Shoulder region)
0.290 0.710 0.000
M85.40 Solitary bone cyst (Multiple sites)
0.290 0.710 0.000
M85.59 Aneurysmal bone cyst (Site unspecified)
0.290 0.710 0.000
M85.58 Aneurysmal bone cyst (Other)
0.290 0.710 0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)
0.290 0.710 0.000
M85.56 Aneurysmal bone cyst (Lower leg)
0.290 0.710 0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)
0.290 0.710 0.000
M85.54 Aneurysmal bone cyst (Hand)
0.290 0.710 0.000
M85.53 Aneurysmal bone cyst (Forearm)
0.290 0.710 0.000
M85.52 Aneurysmal bone cyst (Upper arm)
0.290 0.710 0.000
M85.51 Aneurysmal bone cyst (Shoulder region)
0.290 0.710 0.000
M85.50 Aneurysmal bone cyst (Multiple sites)
0.290 0.710 0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)
0.290 0.710 0.000
M85.98 Disorder of bone density and structure, unspecified (Other)
0.290 0.710 0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)
0.290 0.710 0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)
0.290 0.710 0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)
0.290 0.710 0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)
0.290 0.710 0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)
0.290 0.710 0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)
0.290 0.710 0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)
0.290 0.710 0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)
0.290 0.710 0.000
M62.8 Other specified disorders of muscle
0.288 0.712 0.000
M19.00 Primary arthrosis of other joints (Multiple sites)
0.288 0.712 0.000
M66 Spontaneous rupture of synovium and tendon
0.286 0.714 0.000
M12.3 Palindromic rheumatism
0.286 0.714 0.000
M13.09 Polyarthritis, unspecified (Site unspecified)
0.286 0.714 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.285 0.715 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.285 0.715 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.285 0.715 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.284 0.716 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.283 0.717 0.000
M08.9 Juvenile arthritis, unspecified
0.281 0.718 0.000
M08.8 Other juvenile arthritis
0.281 0.718 0.000
M08.4 Pauciarticular juvenile arthritis
0.281 0.718 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.281 0.718 0.000
M08.2 Juvenile arthritis with systemic onset
0.281 0.718 0.000
M08.1 Juvenile ankylosing spondylitis
0.281 0.718 0.000
M08.0 Juvenile rheumatoid arthritis
0.281 0.718 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.281 0.718 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.281 0.718 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.281 0.718 0.000
M09.0 Juvenile arthritis in psoriasis
0.281 0.718 0.000
M46.4 Discitis, unspecified
0.280 0.720 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.280 0.720 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.280 0.720 0.000
M84.29 Delayed union of fracture (Site unspecified)
0.279 0.721 0.000
M84.28 Delayed union of fracture (Other)
0.279 0.721 0.000
M84.27 Delayed union of fracture (Ankle and foot)
0.279 0.721 0.000
M84.26 Delayed union of fracture (Lower leg)
0.279 0.721 0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)
0.279 0.721 0.000
M84.24 Delayed union of fracture (Hand)
0.279 0.721 0.000
M84.23 Delayed union of fracture (Forearm)
0.279 0.721 0.000
M84.22 Delayed union of fracture (Upper arm)
0.279 0.721 0.000
M84.21 Delayed union of fracture (Shoulder region)
0.279 0.721 0.000
M84.20 Delayed union of fracture (Multiple sites)
0.279 0.721 0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)
0.279 0.721 0.000
M84.38 Stress fracture, not elsewhere classified (Other)
0.279 0.721 0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)
0.279 0.721 0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)
0.279 0.721 0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)
0.279 0.721 0.000
M84.34 Stress fracture, not elsewhere classified (Hand)
0.279 0.721 0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)
0.279 0.721 0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)
0.279 0.721 0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)
0.279 0.721 0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)
0.279 0.721 0.000
M84.89 Other disorders of continuity of bone (Site unspecified)
0.279 0.721 0.000
M84.88 Other disorders of continuity of bone (Other)
0.279 0.721 0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)
0.279 0.721 0.000
M84.86 Other disorders of continuity of bone (Lower leg)
0.279 0.721 0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)
0.279 0.721 0.000
M84.84 Other disorders of continuity of bone (Hand)
0.279 0.721 0.000
M84.83 Other disorders of continuity of bone (Forearm)
0.279 0.721 0.000
M84.82 Other disorders of continuity of bone (Upper arm)
0.279 0.721 0.000
M84.81 Other disorders of continuity of bone (Shoulder region)
0.279 0.721 0.000
M84.80 Other disorders of continuity of bone (Multiple sites)
0.279 0.721 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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