TreeWAS – Variant ID: rs1247563

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I25.8 Other forms of chronic ischaemic heart disease	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
I20 Angina pectoris	1.000	0.000	0.000
I20.9 Angina pectoris, unspecified	0.997	0.003	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.994	0.006	0.000
I20.0 Unstable angina	0.977	0.023	0.000
I22 Subsequent myocardial infarction	0.975	0.025	0.000
I21 Acute myocardial infarction	0.960	0.040	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.953	0.047	0.000
I25.2 Old myocardial infarction	0.941	0.059	0.000
D12.3 Transverse colon	0.000	0.079	0.921
I22.1 Subsequent myocardial infarction of inferior wall	0.918	0.082	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.000	0.093	0.907
D12.8 Rectum	0.000	0.098	0.902
I22.9 Subsequent myocardial infarction of unspecified site	0.893	0.107	0.000
I21.9 Acute myocardial infarction, unspecified	0.792	0.208	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.779	0.221	0.000
I23 Certain current complications following acute myocardial infarction	0.774	0.226	0.000
I25.4 Coronary artery aneurysm	0.744	0.256	0.000
D12.4 Descending colon	0.000	0.271	0.729
I25.0 Atherosclerotic cardiovascular disease, so described	0.725	0.275	0.000
I22.8 Subsequent myocardial infarction of other sites	0.719	0.281	0.000
I25.6 Silent myocardial ischaemia	0.717	0.283	0.000
D12.6 Colon, unspecified	0.000	0.284	0.716
D12.1 Appendix	0.000	0.285	0.715
I20.8 Other forms of angina pectoris	0.711	0.289	0.000
D12.9 Anus and anal canal	0.000	0.305	0.695
I21.X Presumed acute myicardial infaction (unconfirmed)	0.688	0.312	0.000
I25.5 Ischaemic cardiomyopathy	0.684	0.316	0.000
D12.5 Sigmoid colon	0.000	0.318	0.682
D12.0 Caecum	0.000	0.320	0.680
I22.0 Subsequent myocardial infarction of anterior wall	0.662	0.338	0.000
D12.7 Rectosigmoid junction	0.000	0.345	0.655
I20.1 Angina pectoris with documented spasm	0.646	0.354	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.631	0.369	0.000
I23.8 Other current complications following acute myocardial infarction	0.611	0.388	0.000
I25.3 Aneurysm of heart	0.574	0.426	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.555	0.445	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.555	0.445	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.555	0.445	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.555	0.445	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.555	0.445	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.555	0.445	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.555	0.445	0.000
I24 Other acute ischaemic heart diseases	0.543	0.457	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.462	0.538	0.000
D12.2 Ascending colon	0.000	0.573	0.427
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.392	0.608	0.000
I24.1 Dressler's syndrome	0.342	0.657	0.000
Z95.1 Presence of aortocoronary bypass graft	0.337	0.663	0.000
E78.0 Pure hypercholesterolaemia	0.211	0.789	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.203	0.797	0.000
E78.5 Hyperlipidaemia, unspecified	0.192	0.808	0.000
E78.2 Mixed hyperlipidaemia	0.181	0.819	0.000
E78.4 Other hyperlipidaemia	0.175	0.825	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.163	0.837	0.000
E78.8 Other disorders of lipoprotein metabolism	0.160	0.840	0.000
I21.4 Acute subendocardial myocardial infarction	0.154	0.846	0.000
E78.1 Pure hyperglyceridaemia	0.153	0.847	0.000
E78.6 Lipoprotein deficiency	0.151	0.849	0.000
Z95.3 Presence of xenogenic heart valve	0.149	0.851	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.147	0.853	0.000
E78.3 Hyperchylomicronaemia	0.146	0.854	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.143	0.857	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.133	0.867	0.000
K70.9 Alcoholic liver disease, unspecified	0.123	0.877	0.000
K70.3 Alcoholic cirrhosis of liver	0.122	0.878	0.000
K70 Alcoholic liver disease	0.122	0.878	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.110	0.889	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.110	0.890	0.000
K70.4 Alcoholic hepatic failure	0.103	0.897	0.000
Z95.4 Presence of other heart-valve replacement	0.103	0.897	0.000
K70.1 Alcoholic hepatitis	0.098	0.902	0.000
K70.0 Alcoholic fatty liver	0.097	0.903	0.000
H33.2 Serous retinal detachment	0.095	0.905	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.089	0.911	0.000
Z95.2 Presence of prosthetic heart valve	0.086	0.914	0.000
I24.8 Other forms of acute ischaemic heart disease	0.060	0.940	0.000
C50.4 Upper-outer quadrant of breast	0.033	0.967	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.990	0.010
Z86.0 Personal history of other neoplasms	0.000	0.990	0.010
Z95.0 Presence of cardiac pacemaker	0.008	0.992	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.008	0.992	0.000
H33 Retinal detachments and breaks	0.008	0.992	0.000
E70-E90 Metabolic disorders	0.007	0.993	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.993	0.007
M96.0 Pseudarthrosis after fusion or arthrodesis	0.006	0.994	0.000
I74.5 Embolism and thrombosis of iliac artery	0.006	0.994	0.000
H33.5 Other retinal detachments	0.006	0.994	0.000
E88 Other metabolic disorders	0.006	0.994	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.006	0.994	0.000
M35.3 Polymyalgia rheumatica	0.000	0.994	0.006
E84 Cystic fibrosis	0.006	0.994	0.000
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.994	0.006
Chapter IX Diseases of the circulatory system	0.006	0.994	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.005	0.995	0.000
E77 Disorders of glycoprotein metabolism	0.005	0.995	0.000
E76 Disorders of glycosaminoglycan metabolism	0.005	0.995	0.000
E72 Other disorders of amino-acid metabolism	0.005	0.995	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.005	0.995	0.000
E70 Disorders of aromatic amino-acid metabolism	0.005	0.995	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.005	0.995	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.005	0.995	0.000
K70-K77 Diseases of liver	0.005	0.995	0.000
E73 Lactose intolerance	0.005	0.995	0.000
I74 Arterial embolism and thrombosis	0.005	0.995	0.000
E74 Other disorders of carbohydrate metabolism	0.005	0.995	0.000
S02.2 Fracture of nasal bones	0.000	0.995	0.005
E79 Disorders of purine and pyrimidine metabolism	0.005	0.995	0.000
C50.1 Central portion of breast	0.005	0.995	0.000
E88.2 Lipomatosis, not elsewhere classified	0.005	0.995	0.000
F81 Specific developmental disorders of scholastic skills	0.005	0.995	0.000
H33.4 Traction detachment of retina	0.005	0.995	0.000
I99 Other and unspecified disorders of circulatory system	0.005	0.995	0.000
G62.9 Polyneuropathy, unspecified	0.005	0.995	0.000
R76.8 Other specified abnormal immunological findings in serum	0.005	0.995	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.005	0.995	0.000
I27.2 Other secondary pulmonary hypertension	0.005	0.995	0.000
E88.3 Tumour lysis syndrome	0.005	0.995	0.000
E85 Amyloidosis	0.005	0.995	0.000
I70 Atherosclerosis	0.005	0.995	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.005	0.995	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.005	0.995	0.000
E84.9 Cystic fibrosis, unspecified	0.004	0.995	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.005	0.995	0.000
E88.9 Metabolic disorder, unspecified	0.004	0.995	0.000
E88.8 Other specified metabolic disorders	0.004	0.995	0.000
C50 Malignant neoplasm of breast	0.005	0.995	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.004	0.996	0.000
H33.1 Retinoschisis and retinal cysts	0.004	0.996	0.000
E83 Disorders of mineral metabolism	0.004	0.996	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.004	0.996	0.000
E86 Volume depletion	0.004	0.996	0.000
E84.8 Cystic fibrosis with other manifestations	0.004	0.996	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.004	0.996	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.004	0.996	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.004	0.996	0.000
K72 Hepatic failure, not elsewhere classified	0.004	0.996	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.004	0.996	0.000
H33.0 Retinal detachment with retinal break	0.004	0.996	0.000
I00-I02 Acute rheumatic fever	0.004	0.996	0.000
E75.5 Other lipid storage disorders	0.004	0.996	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.004	0.996	0.000
K73 Chronic hepatitis, not elsewhere classified	0.004	0.996	0.000
E75.6 Lipid storage disorder, unspecified	0.004	0.996	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.004	0.996	0.000
E75.3 Sphingolipidosis, unspecified	0.004	0.996	0.000
E75.2 Other sphingolipidosis	0.004	0.996	0.000
E75.1 Other gangliosidosis	0.004	0.996	0.000
E75.0 GM2 gangliosidosis	0.004	0.996	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.004	0.996	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.004	0.996	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.004	0.996	0.000
E70.3 Albinism	0.004	0.996	0.000
E70.2 Disorders of tyrosine metabolism	0.004	0.996	0.000
E70.1 Other hyperphenylalaninaemias	0.004	0.996	0.000
E70.0 Classical phenylketonuria	0.004	0.996	0.000
E71.3 Disorders of fatty-acid metabolism	0.004	0.996	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.004	0.996	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.004	0.996	0.000
E71.0 Maple-syrup-urine disease	0.004	0.996	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.004	0.996	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.004	0.996	0.000
E72.5 Disorders of glycine metabolism	0.004	0.996	0.000
E72.4 Disorders of ornithine metabolism	0.004	0.996	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.004	0.996	0.000
E72.2 Disorders of urea cycle metabolism	0.004	0.996	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.004	0.996	0.000
E72.0 Disorders of amino-acid transport	0.004	0.996	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.004	0.996	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.004	0.996	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.004	0.996	0.000
E76.2 Other mucopolysaccharidoses	0.004	0.996	0.000
E76.1 Mucopolysaccharidosis, type II	0.004	0.996	0.000
E76.0 Mucopolysaccharidosis, type I	0.004	0.996	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.004	0.996	0.000
E77.8 Other disorders of glycoprotein metabolism	0.004	0.996	0.000
E77.1 Defects in glycoprotein degradation	0.004	0.996	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.004	0.996	0.000
K77 Liver disorders in diseases classified elsewhere	0.004	0.996	0.000
K71 Toxic liver disease	0.004	0.996	0.000
E73.8 Other lactose intolerance	0.004	0.996	0.000
E73.1 Secondary lactase deficiency	0.004	0.996	0.000
E73.0 Congenital lactase deficiency	0.004	0.996	0.000
I27 Other pulmonary heart diseases	0.004	0.996	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.004	0.996	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.004	0.996	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.004	0.996	0.000
E74.2 Disorders of galactose metabolism	0.004	0.996	0.000
E74.1 Disorders of fructose metabolism	0.004	0.996	0.000
E74.0 Glycogen storage disease	0.004	0.996	0.000
S02.21 Fracture of nasal bones (open)	0.000	0.996	0.004
K72.9 Hepatic failure, unspecified	0.004	0.996	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.004	0.996	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.004	0.996	0.000
E79.1 Lesch-Nyhan syndrome	0.004	0.996	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.004	0.996	0.000
R76 Other abnormal immunological findings in serum	0.004	0.996	0.000
D73.0 Hyposplenism	0.004	0.996	0.000
F81.8 Other developmental disorders of scholastic skills	0.004	0.996	0.000
F81.3 Mixed disorder of scholastic skills	0.004	0.996	0.000
F81.2 Specific disorder of arithmetical skills	0.004	0.996	0.000
F81.1 Specific spelling disorder	0.004	0.996	0.000
F81.0 Specific reading disorder	0.004	0.996	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.004	0.996	0.000
E73.9 Lactose intolerance, unspecified	0.004	0.996	0.000
E83.1 Disorders of iron metabolism	0.004	0.996	0.000
I73.9 Peripheral vascular disease, unspecified	0.004	0.996	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.004	0.996	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.004	0.996	0.000
Z09.0 Follow-up examination after surgery for other conditions	0.000	0.996	0.004
R74.8 Abnormal levels of other serum enzymes	0.004	0.996	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.004	0.996	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.004	0.996	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.004	0.996	0.000
E85.9 Amyloidosis, unspecified	0.004	0.996	0.000
E85.3 Secondary systemic amyloidosis	0.004	0.996	0.000
E85.8 Other amyloidosis	0.004	0.996	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.004	0.996	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.004	0.996	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.004	0.996	0.000
I73 Other peripheral vascular diseases	0.004	0.996	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.004	0.996	0.000
E83.5 Disorders of calcium metabolism	0.004	0.996	0.000
I35.0 Aortic (valve) stenosis	0.004	0.996	0.000
I74.8 Embolism and thrombosis of other arteries	0.004	0.996	0.000
I70.9 Generalised and unspecified atherosclerosis	0.003	0.996	0.000
I70.0 Atherosclerosis of aorta	0.004	0.996	0.000
I70.8 Atherosclerosis of other arteries	0.003	0.996	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.003	0.996	0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.000	0.996	0.004
R74 Abnormal serum enzyme levels	0.003	0.996	0.000
C50.3 Lower-inner quadrant of breast	0.003	0.997	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.003	0.997	0.000
E83.8 Other disorders of mineral metabolism	0.003	0.997	0.000
E83.2 Disorders of zinc metabolism	0.003	0.997	0.000
E83.0 Disorders of copper metabolism	0.003	0.997	0.000
I28 Other diseases of pulmonary vessels	0.003	0.997	0.000
I27.0 Primary pulmonary hypertension	0.003	0.997	0.000
K51.2 Ulcerative (chronic) proctitis	0.003	0.997	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.003	0.997	0.000
K72.1 Chronic hepatic failure	0.003	0.997	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.003	0.997	0.000
C50.6 Axillary tail of breast	0.003	0.997	0.000
L29.0 Pruritus ani	0.000	0.997	0.003
I02 Rheumatic chorea	0.003	0.997	0.000
I01 Rheumatic fever with heart involvement	0.003	0.997	0.000
I00 Rheumatic fever without mention of heart involvement	0.003	0.997	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.003	0.997	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.003	0.997	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.003	0.997	0.000
G80.9 Infantile cerebral palsy, unspecified	0.003	0.997	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.003	0.997	0.000
K73.9 Chronic hepatitis, unspecified	0.003	0.997	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.003	0.997	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.003	0.997	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.003	0.997	0.000
K71.9 Toxic liver disease, unspecified	0.003	0.997	0.000
K71.8 Toxic liver disease with other disorders of liver	0.003	0.997	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.003	0.997	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.003	0.997	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.003	0.997	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.003	0.997	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.003	0.997	0.000
K71.2 Toxic liver disease with acute hepatitis	0.003	0.997	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.003	0.997	0.000
K71.0 Toxic liver disease with cholestasis	0.003	0.997	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.003	0.997	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
E80.1 Porphyria cutanea tarda	0.003	0.997	0.000
I27.1 Kyphoscoliotic heart disease	0.003	0.997	0.000
R76.0 Raised antibody titer	0.003	0.997	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.003	0.997	0.000
C50.2 Upper-inner quadrant of breast	0.003	0.997	0.000
I70.1 Atherosclerosis of renal artery	0.003	0.997	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.003	0.997	0.000
R76.9 Abnormal immunological finding in serum, unspecified	0.003	0.997	0.000
R76.2 False-positive serological test for syphilis	0.003	0.997	0.000
R76.1 Abnormal reaction to tuberculin test	0.003	0.997	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.003	0.997	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.003	0.997	0.000
E80.5 Crigler-Najjar syndrome	0.003	0.997	0.000
E80.3 Defects of catalase and peroxydase	0.003	0.997	0.000
E80.2 Other porphyria	0.003	0.997	0.000
E80.0 Hereditary erythropoietic porphyria	0.003	0.997	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.003	0.997	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.003	0.997	0.000
E85.4 Organ-limited amyloidosis	0.003	0.997	0.000
I78 Diseases of capillaries	0.003	0.997	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.003	0.997	0.000
I79.1 Aortitis in diseases classified elsewhere	0.003	0.997	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.003	0.997	0.000
F80-F89 Disorders of psychological development	0.003	0.997	0.000
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.003	0.997	0.000
M85.8 Other specified disorders of bone density and structure	0.003	0.997	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.003	0.997	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
I98.0 Cardiovascular syphilis	0.003	0.997	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.003	0.997	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.003	0.997	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.003	0.997	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.003	0.997	0.000
E80.6 Other disorders of bilirubin metabolism	0.003	0.997	0.000
E83.3 Disorders of phosphorus metabolism	0.003	0.997	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.003	0.997	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.003	0.997	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.003	0.997	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.003	0.997	0.000
E55.9 Vitamin D deficiency, unspecified	0.003	0.997	0.000
F84 Pervasive developmental disorders	0.003	0.997	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.003	0.997	0.000
R74.9 Abnormal level of unspecified serum enzyme	0.003	0.997	0.000
I77 Other disorders of arteries and arterioles	0.003	0.997	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.003	0.997	0.000
I28.1 Aneurysm of pulmonary artery	0.003	0.997	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.003	0.997	0.000
I28.8 Other specified diseases of pulmonary vessels	0.003	0.997	0.000
K72.0 Acute and subacute hepatic failure	0.003	0.997	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.003	0.997	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.003	0.997	0.000
S06.2 Diffuse brain injury	0.003	0.997	0.000
I35.9 Aortic valve disorder, unspecified	0.003	0.997	0.000
I95.2 Hypotension due to drugs	0.003	0.997	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.003	0.997	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.002	0.997	0.000
I01.8 Other acute rheumatic heart disease	0.002	0.997	0.000
I01.2 Acute rheumatic myocarditis	0.002	0.997	0.000
I01.1 Acute rheumatic endocarditis	0.002	0.997	0.000
I01.0 Acute rheumatic pericarditis	0.002	0.997	0.000
I02.9 Rheumatic chorea without heart involvement	0.002	0.997	0.000
I02.0 Rheumatic chorea with heart involvement	0.002	0.997	0.000
C50.0 Nipple and areola	0.003	0.997	0.000
I26 Pulmonary embolism	0.003	0.997	0.000
I73.8 Other specified peripheral vascular diseases	0.002	0.997	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.003	0.997	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.003	0.997	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.003	0.997	0.000
F84.0 Childhood autism	0.002	0.997	0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.002	0.997	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.002	0.997	0.000
M96.5 Postradiation scoliosis	0.002	0.997	0.000
M96.4 Postsurgical lordosis	0.002	0.997	0.000
M96.3 Postlaminectomy kyphosis	0.002	0.997	0.000
M96.2 Postradiation kyphosis	0.002	0.997	0.000
I35 Nonrheumatic aortic valve disorders	0.003	0.997	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.002	0.997	0.000
H60.9 Otitis externa, unspecified	0.003	0.997	0.000
I77.2 Rupture of artery	0.002	0.997	0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.002	0.997	0.000
H18.8 Other specified disorders of cornea	0.002	0.997	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.002	0.997	0.000
I72 Other aneurysm	0.002	0.998	0.000
I95 Hypotension	0.002	0.998	0.000
N62 Hypertrophy of breast	0.002	0.998	0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.002	0.998	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.002	0.998	0.000
I78.9 Disease of capillaries, unspecified	0.002	0.998	0.000
F80 Specific developmental disorders of speech and language	0.002	0.998	0.000
F84.5 Asperger's syndrome	0.002	0.998	0.000
I27.8 Other specified pulmonary heart diseases	0.002	0.998	0.000
G62 Other polyneuropathies	0.002	0.998	0.000
I78.1 Naevus, nonneoplastic	0.002	0.998	0.000
F89 Unspecified disorder of psychological development	0.002	0.998	0.000
F88 Other disorders of psychological development	0.002	0.998	0.000
F83 Mixed specific developmental disorders	0.002	0.998	0.000
F82 Specific developmental disorder of motor function	0.002	0.998	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.002	0.998	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.002	0.998	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.002	0.998	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.002	0.998	0.000
H18.6 Keratoconus	0.002	0.998	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.002	0.998	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
J43.9 Emphysema, unspecified	0.000	0.998	0.002
J86.9 Pyothorax without fistula	0.000	0.998	0.002
S63.6 Sprain and strain of finger(s)	0.002	0.998	0.000
S63.5 Sprain and strain of wrist	0.002	0.998	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.002	0.998	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.998	0.002
S06.5 Traumatic subdural haemorrhage	0.002	0.998	0.000
S06 Intracranial injury	0.002	0.998	0.000
I77.0 Arteriovenous fistula, acquired	0.002	0.998	0.000
R78 Findings of drugs and other substances, not normally found in blood	0.002	0.998	0.000
F84.9 Pervasive developmental disorder, unspecified	0.002	0.998	0.000
F84.8 Other pervasive developmental disorders	0.002	0.998	0.000
F84.4 Overactive disorder associated with mental retardation and stereotyped movements	0.002	0.998	0.000
F84.3 Other childhood disintegrative disorder	0.002	0.998	0.000
F84.2 Rett's syndrome	0.002	0.998	0.000
F84.1 Atypical autism	0.002	0.998	0.000
I77.5 Necrosis of artery	0.002	0.998	0.000
I77.4 Coeliac artery compression syndrome	0.002	0.998	0.000
I77.3 Arterial fibromuscular dysplasia	0.002	0.998	0.000
I72.1 Aneurysm of artery of upper extremity	0.002	0.998	0.000
S02.50 Fracture of tooth (closed)	0.000	0.998	0.002
I95.0 Idiopathic hypotension	0.002	0.998	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.002	0.998	0.000
I77.8 Other specified disorders of arteries and arterioles	0.002	0.998	0.000
I78.8 Other diseases of capillaries	0.002	0.998	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.002	0.998	0.000
H18.5 Hereditary corneal dystrophies	0.002	0.998	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.002	0.998	0.000
R71 Abnormality of red blood cells	0.002	0.998	0.000
G62.0 Drug-induced polyneuropathy	0.002	0.998	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
H18 Other disorders of cornea	0.002	0.998	0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.000	0.998	0.002
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.002	0.998	0.000
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)	0.002	0.998	0.000
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate	0.002	0.998	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.002	0.998	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.002	0.998	0.000
E89.5 Postprocedural testicular hypofunction	0.002	0.998	0.000
E89.2 Postprocedural hypoparathyroidism	0.002	0.998	0.000
E89.1 Postprocedural hypoinsulinaemia	0.002	0.998	0.000
M85 Other disorders of bone density and structure	0.002	0.998	0.000
R79 Other abnormal findings of blood chemistry	0.002	0.998	0.000
I72.4 Aneurysm of artery of lower extremity	0.002	0.998	0.000
G80 Infantile cerebral palsy	0.002	0.998	0.000
S06.8 Other intracranial injuries	0.002	0.998	0.000
T78.4 Allergy, unspecified	0.000	0.998	0.002
L85.9 Epidermal thickening, unspecified	0.000	0.998	0.002
I72.6 Aneurysm and dissection of vertebral artery	0.002	0.998	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.002	0.998	0.000
Z63.4 Disappearance and death of family member	0.002	0.998	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.001	0.998	0.001
G25.8 Other specified extrapyramidal and movement disorders	0.002	0.998	0.000
R04.2 Haemoptysis	0.000	0.998	0.002
R77 Other abnormalities of plasma proteins	0.002	0.998	0.000
C22.0 Liver cell carcinoma	0.002	0.998	0.000
F80.9 Developmental disorder of speech and language, unspecified	0.002	0.998	0.000
F80.8 Other developmental disorders of speech and language	0.002	0.998	0.000
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]	0.002	0.998	0.000
F80.2 Receptive language disorder	0.002	0.998	0.000
F80.1 Expressive language disorder	0.002	0.998	0.000
F80.0 Specific speech articulation disorder	0.002	0.998	0.000
G62.2 Polyneuropathy due to other toxic agents	0.002	0.998	0.000
G62.1 Alcoholic polyneuropathy	0.002	0.998	0.000
R70.1 Abnormal plasma viscosity	0.002	0.998	0.000
G25.3 Myoclonus	0.002	0.998	0.000
I72.3 Aneurysm of iliac artery	0.002	0.998	0.000
R79.0 Abnormal level of blood mineral	0.002	0.998	0.000
E89.4 Postprocedural ovarian failure	0.002	0.998	0.000
I77.6 Arteritis, unspecified	0.002	0.998	0.000
M85.0 Fibrous dysplasia (monostotic)	0.002	0.998	0.000
E89.3 Postprocedural hypopituitarism	0.002	0.998	0.000
I72.2 Aneurysm of renal artery	0.002	0.998	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.002	0.998	0.000
S06.0 Concussion	0.002	0.998	0.000
R73 Elevated blood glucose level	0.002	0.998	0.000
C50-C50 Malignant neoplasm of breast	0.002	0.998	0.000
I27.9 Pulmonary heart disease, unspecified	0.002	0.998	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.002	0.998	0.000
I97.0 Postcardiotomy syndrome	0.002	0.998	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.002	0.998	0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.000	0.998	0.002
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.002	0.998	0.000
S42.30 Fracture of shaft of humerus (closed)	0.002	0.998	0.000
G80.2 Infantile hemiplegia	0.002	0.998	0.000
R78.9 Finding of unspecified substance, not normally found in blood	0.002	0.998	0.000
R78.7 Finding of abnormal level of heavy metals in blood	0.002	0.998	0.000
R78.6 Finding of steroid agent in blood	0.002	0.998	0.000
R78.5 Finding of psychotropic drug in blood	0.002	0.998	0.000
R78.4 Finding of other drugs of addictive potential in blood	0.002	0.998	0.000
R78.3 Finding of hallucinogen in blood	0.002	0.998	0.000
R78.2 Finding of cocaine in blood	0.002	0.998	0.000
R78.1 Finding of opiate drug in blood	0.002	0.998	0.000
S06.7 Intracranial injury with prolonged coma	0.002	0.998	0.000
S06.1 Traumatic cerebral oedema	0.002	0.998	0.000
S09.9 Unspecified injury of head	0.000	0.998	0.002
S06.80 Other intracranial injuries (without open intracranial wound)	0.002	0.998	0.000
C50.8 Overlapping lesion of breast	0.002	0.998	0.000
G80.8 Other infantile cerebral palsy	0.002	0.998	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.002	0.998	0.000
R78.8 Finding of other specified substances, not normally found in blood	0.002	0.998	0.000
Z64.0 Problems related to unwanted pregnancy	0.002	0.998	0.000
H18.4 Corneal degeneration	0.002	0.998	0.000
H18.2 Other corneal oedema	0.002	0.998	0.000
M85.4 Solitary bone cyst	0.002	0.998	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.002	0.998	0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.002	0.998	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.000	0.998	0.002
G80.0 Spastic cerebral palsy	0.002	0.998	0.000
S06.3 Focal brain injury	0.002	0.998	0.000
S19.9 Unspecified injury of neck	0.002	0.998	0.000
M79.18 Myalgia (Other)	0.002	0.998	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.998	0.002
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.002	0.998	0.000
R77.1 Abnormality of globulin	0.002	0.998	0.000
H18.7 Other corneal deformities	0.002	0.998	0.000
H18.3 Changes in corneal membranes	0.002	0.998	0.000
H18.0 Corneal pigmentations and deposits	0.002	0.998	0.000
Q27.3 Peripheral arteriovenous malformation	0.000	0.998	0.002
Z09.3 Follow-up examination after psychotherapy	0.000	0.998	0.002
Z09.1 Follow-up examination after radiotherapy for other conditions	0.000	0.998	0.002
I97.2 Postmastectomy lymphoedema syndrome	0.002	0.998	0.000
M85.9 Disorder of bone density and structure, unspecified	0.002	0.998	0.000
M85.5 Aneurysmal bone cyst	0.002	0.998	0.000
M85.3 Osteitis condensans	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations