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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12492298
log Bayes Factor = 14.9582
Chromosome 3   position 65,720,358  (GRCh37) Explore rs12492298 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
J44 Other chronic obstructive pulmonary disease
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
K22 Other diseases of oesophagus
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
I60-I69 Cerebrovascular diseases
0.998 0.002 0.000
K22.1 Ulcer of oesophagus
0.996 0.004 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.995 0.005 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.993 0.007 0.000
B95-B98 Bacterial, viral and other infectious agents
0.993 0.007 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.989 0.011 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.985 0.015 0.000
K31 Other diseases of stomach and duodenum
0.982 0.018 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.980 0.020 0.000
K29 Gastritis and duodenitis
0.980 0.020 0.000
K29.7 Gastritis, unspecified
0.976 0.024 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.975 0.025 0.000
J09-J18 Influenza and pneumonia
0.973 0.027 0.000
K90-K93 Other diseases of the digestive system
0.972 0.028 0.000
J90-J94 Other diseases of pleura
0.971 0.029 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.969 0.031 0.000
I63 Cerebral infarction
0.968 0.032 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.967 0.033 0.000
K90 Intestinal malabsorption
0.964 0.036 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.962 0.038 0.000
K22.2 Oesophageal obstruction
0.960 0.040 0.000
K31.8 Other specified diseases of stomach and duodenum
0.957 0.043 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.956 0.044 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.954 0.046 0.000
J47 Bronchiectasis
0.952 0.048 0.000
K22.8 Other specified diseases of oesophagus
0.950 0.050 0.000
E10-E14 Diabetes mellitus
0.947 0.053 0.000
K90.0 Coeliac disease
0.946 0.054 0.000
S60-S69 Injuries to the wrist and hand
0.943 0.057 0.000
Z02 Examination and encounter for administrative purposes
0.934 0.066 0.000
I60 Subarachnoid haemorrhage
0.929 0.071 0.000
J18 Pneumonia, organism unspecified
0.928 0.072 0.000
Z50 Care involving use of rehabilitation procedures
0.927 0.073 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.926 0.074 0.000
I73 Other peripheral vascular diseases
0.925 0.075 0.000
Z03.4 Observation for suspected myocardial infarction
0.925 0.075 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.921 0.079 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.919 0.081 0.000
E11 Non-insulin-dependent diabetes mellitus
0.919 0.081 0.000
K26 Duodenal ulcer
0.917 0.083 0.000
E20-E35 Disorders of other endocrine glands
0.917 0.083 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.913 0.087 0.000
K20 Oesophagitis
0.910 0.090 0.000
I63.9 Cerebral infarction, unspecified
0.909 0.091 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.907 0.093 0.000
I20-I25 Ischaemic heart diseases
0.906 0.094 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.905 0.095 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.903 0.097 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.900 0.100 0.000
I73.9 Peripheral vascular disease, unspecified
0.900 0.100 0.000
E11.9 Without complications
0.899 0.101 0.000
Z63 Other problems related to primary support group, including family circumstances
0.895 0.105 0.000
Z02.8 Other examinations for administrative purposes
0.894 0.106 0.000
I20 Angina pectoris
0.894 0.106 0.000
J93 Pneumothorax
0.891 0.109 0.000
K35-K38 Diseases of appendix
0.889 0.111 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.888 0.112 0.000
I20.0 Unstable angina
0.888 0.112 0.000
A30-A49 Other bacterial diseases
0.884 0.116 0.000
Z50.1 Other physical therapy
0.880 0.120 0.000
E00-E07 Disorders of thyroid gland
0.878 0.122 0.000
Z04 Examination and observation for other reasons
0.876 0.124 0.000
I69 Sequelae of cerebrovascular disease
0.876 0.124 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.876 0.124 0.000
Z13 Special screening examination for other diseases and disorders
0.874 0.126 0.000
J18.0 Bronchopneumonia, unspecified
0.869 0.131 0.000
Z13.9 Special screening examination, unspecified
0.862 0.138 0.000
Z46 Fitting and adjustment of other devices
0.862 0.138 0.000
E14 Unspecified diabetes mellitus
0.861 0.139 0.000
I62 Other nontraumatic intracranial haemorrhage
0.860 0.140 0.000
J92 Pleural plaque
0.857 0.143 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.856 0.144 0.000
Chapter V Mental and behavioural disorders
0.855 0.145 0.000
S20-S29 Injuries to the thorax
0.854 0.146 0.000
B15-B19 Viral hepatitis
0.853 0.147 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.853 0.147 0.000
J84 Other interstitial pulmonary diseases
0.852 0.148 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.852 0.148 0.000
Z41 Procedures for purposes other than remedying health state
0.850 0.150 0.000
S62 Fracture at wrist and hand level
0.849 0.151 0.000
Z60 Problems related to social environment
0.848 0.152 0.000
K90.9 Intestinal malabsorption, unspecified
0.844 0.156 0.000
J91 Pleural effusion in conditions classified elsewhere
0.842 0.158 0.000
K29.2 Alcoholic gastritis
0.840 0.160 0.000
E11.5 With peripheral circulatory complications
0.838 0.162 0.000
A00-A09 Intestinal infectious diseases
0.832 0.168 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.831 0.169 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.828 0.172 0.000
K22.9 Disease of oesophagus, unspecified
0.826 0.174 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.824 0.176 0.000
Chapter XXII Codes for special purposes
0.818 0.182 0.000
J93.9 Pneumothorax, unspecified
0.816 0.184 0.000
K35 Acute appendicitis
0.812 0.188 0.000
T43.2 Other and unspecified antidepressants
0.809 0.191 0.000
Z04.9 Examination and observation for unspecified reason
0.805 0.195 0.000
E14.9 Without complications
0.805 0.195 0.000
E28 Ovarian dysfunction
0.805 0.195 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.803 0.197 0.000
E04 Other non-toxic goitre
0.802 0.198 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.801 0.199 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.798 0.202 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.795 0.205 0.000
A80-A89 Viral infections of the central nervous system
0.795 0.205 0.000
K26.7 Chronic without haemorrhage or perforation
0.795 0.205 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.794 0.206 0.000
B35-B49 Mycoses
0.793 0.207 0.000
Z51 Other medical care
0.793 0.207 0.000
E21.3 Hyperparathyroidism, unspecified
0.792 0.208 0.000
K29.4 Chronic atrophic gastritis
0.788 0.212 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.785 0.215 0.000
Z51.0 Radiotherapy session
0.784 0.216 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.784 0.216 0.000
J18.9 Pneumonia, unspecified
0.784 0.216 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.782 0.218 0.000
A40 Streptococcal septicaemia
0.780 0.220 0.000
I67 Other cerebrovascular diseases
0.777 0.223 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.776 0.224 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.776 0.224 0.000
B99-B99 Other infectious diseases
0.775 0.225 0.000
F60-F69 Disorders of adult personality and behaviour
0.775 0.225 0.000
J43 Emphysema
0.774 0.226 0.000
S64 Injury of nerves at wrist and hand level
0.771 0.229 0.000
Z63.4 Disappearance and death of family member
0.769 0.231 0.000
Z50.0 Cardiac rehabilitation
0.769 0.231 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.768 0.232 0.000
B50-B64 Protozoal diseases
0.766 0.233 0.000
I71 Aortic aneurysm and dissection
0.766 0.234 0.000
S68 Traumatic amputation of wrist and hand
0.766 0.234 0.000
S62.6 Fracture of other finger
0.766 0.234 0.000
Z58 Problems related to physical environment
0.765 0.235 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.764 0.236 0.000
Z60.2 Living alone
0.763 0.237 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.763 0.237 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.762 0.238 0.000
Z63.0 Problems in relationship with spouse or partner
0.762 0.238 0.000
S90-S99 Injuries to the ankle and foot
0.762 0.238 0.000
I60.8 Other subarachnoid haemorrhage
0.762 0.238 0.000
I30-I52 Other forms of heart disease
0.760 0.240 0.000
J94 Other pleural conditions
0.758 0.242 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.758 0.242 0.000
D80-D89 Certain disorders involving the immune mechanism
0.758 0.242 0.000
S10-S19 Injuries to the neck
0.757 0.243 0.000
K29.0 Acute haemorrhagic gastritis
0.755 0.245 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.752 0.248 0.000
J11 Influenza, virus not identified
0.750 0.250 0.000
I70 Atherosclerosis
0.750 0.250 0.000
Z46.6 Fitting and adjustment of urinary device
0.750 0.250 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.749 0.251 0.000
S27 Injury of other and unspecified intrathoracic organs
0.749 0.251 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.747 0.253 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.745 0.255 0.000
Z72 Problems related to lifestyle
0.745 0.255 0.000
J92.0 Pleural plaque with presence of asbestos
0.745 0.255 0.000
J81 Pulmonary oedema
0.744 0.256 0.000
Q80-Q89 Other congenital malformations
0.743 0.257 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.742 0.258 0.000
K10 Other diseases of jaws
0.741 0.259 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.740 0.260 0.000
S61 Open wound of wrist and hand
0.740 0.260 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.739 0.261 0.000
K09 Cysts of oral region, not elsewhere classified
0.738 0.262 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.735 0.265 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.733 0.266 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.733 0.267 0.000
S60 Superficial injury of wrist and hand
0.731 0.269 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.728 0.272 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.727 0.273 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.727 0.273 0.000
Z52 Donors of organs and tissues
0.727 0.273 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.726 0.274 0.000
Z50.5 Speech therapy
0.725 0.275 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.724 0.276 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.723 0.277 0.000
Z40 Prophylactic surgery
0.722 0.277 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.722 0.278 0.000
E04.2 Non-toxic multinodular goitre
0.721 0.279 0.000
J10 Influenza due to identified influenza virus
0.720 0.280 0.000
K35.8 Acute appendicitis, other and unspecified
0.719 0.281 0.000
Chapter VII Diseases of the eye and adnexa
0.718 0.282 0.000
Z54 Convalescence
0.718 0.282 0.000
I51 Complications and ill-defined descriptions of heart disease
0.717 0.283 0.000
K28 Gastrojejunal ulcer
0.717 0.283 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F60 Specific personality disorders
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
K22.3 Perforation of oesophagus
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.716 0.284 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.716 0.284 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.715 0.285 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.714 0.286 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.713 0.287 0.000
K22.0 Achalasia of cardia
0.712 0.288 0.000
B18 Chronic viral hepatitis
0.712 0.288 0.000
Q00-Q07 Congenital malformations of the nervous system
0.712 0.288 0.000
S62.61 Fracture of other finger (open)
0.711 0.289 0.000
Z10 Routine general health check-up of defined subpopulation
0.709 0.291 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.709 0.291 0.000
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters
0.706 0.293 0.000
A46 Erysipelas
0.706 0.294 0.000
A40.8 Other streptococcal septicaemia
0.706 0.294 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.706 0.294 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.705 0.295 0.000
K22.5 Diverticulum of oesophagus, acquired
0.705 0.295 0.000
K31.6 Fistula of stomach and duodenum
0.704 0.296 0.000
K31.4 Gastric diverticulum
0.704 0.296 0.000
K31.3 Pylorospasm, not elsewhere classified
0.704 0.296 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.704 0.296 0.000
K31.0 Acute dilatation of stomach
0.704 0.296 0.000
Q50-Q56 Congenital malformations of genital organs
0.703 0.297 0.000
Z04.3 Examination and observation following other accident
0.703 0.297 0.000
Z72.1 Alcohol use
0.703 0.297 0.000
K29.9 Gastroduodenitis, unspecified
0.703 0.297 0.000
I72 Other aneurysm
0.701 0.299 0.000
S69 Other and unspecified injuries of wrist and hand
0.701 0.299 0.000
E07 Other disorders of thyroid
0.700 0.300 0.000
I20.9 Angina pectoris, unspecified
0.700 0.300 0.000
S62.2 Fracture of first metacarpal bone
0.699 0.301 0.000
Z63.7 Other stressful life events affecting family and household
0.698 0.301 0.000
K26.5 Chronic or unspecified with perforation
0.698 0.302 0.000
J17 Pneumonia in diseases classified elsewhere
0.697 0.302 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.697 0.302 0.000
J12 Viral pneumonia, not elsewhere classified
0.697 0.302 0.000
J09 Influenza due to certain identified influenza virus
0.697 0.302 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.697 0.303 0.000
E06 Thyroiditis
0.697 0.303 0.000
T33-T35 Frostbite
0.694 0.305 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.694 0.305 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.694 0.305 0.000
T00-T07 Injuries involving multiple body regions
0.694 0.305 0.000
E34 Other endocrine disorders
0.694 0.306 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.694 0.306 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.694 0.306 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.694 0.306 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.694 0.306 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.693 0.307 0.000
K05 Gingivitis and periodontal diseases
0.693 0.307 0.000
Z65 Problems related to other psychosocial circumstances
0.693 0.307 0.000
Z64 Problems related to certain psychosocial circumstances
0.693 0.307 0.000
Z62 Other problems related to upbringing
0.693 0.307 0.000
Z61 Problems related to negative life events in childhood
0.693 0.307 0.000
Z59 Problems related to housing and economic circumstances
0.693 0.307 0.000
Z56 Problems related to employment and unemployment
0.693 0.307 0.000
Z55 Problems related to education and literacy
0.693 0.307 0.000
S50-S59 Injuries to the elbow and forearm
0.692 0.307 0.000
I22 Subsequent myocardial infarction
0.692 0.308 0.000
I73.0 Raynaud's syndrome
0.691 0.309 0.000
J46 Status asthmaticus
0.691 0.309 0.000
K90.8 Other intestinal malabsorption
0.691 0.309 0.000
K90.3 Pancreatic steatorrhoea
0.691 0.309 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.691 0.309 0.000
K90.1 Tropical sprue
0.691 0.309 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.690 0.310 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.690 0.310 0.000
Z03.0 Observation for suspected tuberculosis
0.690 0.310 0.000
Z57 Occupational exposure to risk-factors
0.689 0.310 0.000
E11.1 With ketoacidosis
0.689 0.311 0.000
K26.0 Acute with haemorrhage
0.688 0.312 0.000
Z45 Adjustment and management of implanted device
0.688 0.312 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.687 0.313 0.000
I69.3 Sequelae of cerebral infarction
0.686 0.314 0.000
K31.5 Obstruction of duodenum
0.685 0.315 0.000
K35.3 Acute appendicitis with localized peritonitis
0.684 0.316 0.000
Z44 Fitting and adjustment of external prosthetic device
0.684 0.316 0.000
J93.8 Other pneumothorax
0.684 0.316 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.684 0.316 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.683 0.317 0.000
T66-T78 Other and unspecified effects of external causes
0.683 0.317 0.000
E04.9 Non-toxic goitre, unspecified
0.683 0.317 0.000
S80-S89 Injuries to the knee and lower leg
0.682 0.318 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.682 0.318 0.000
K10.8 Other specified diseases of jaws
0.681 0.319 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.681 0.319 0.000
J92.9 Pleural plaque without asbestos
0.681 0.319 0.000
A41 Other septicaemia
0.679 0.321 0.000
E12 Malnutrition-related diabetes mellitus
0.679 0.321 0.000
E26 Hyperaldosteronism
0.678 0.322 0.000
E24 Cushing's syndrome
0.677 0.323 0.000
S65 Injury of blood vessels at wrist and hand level
0.676 0.324 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.674 0.326 0.000
K27 Peptic ulcer, site unspecified
0.674 0.326 0.000
B15 Acute hepatitis A
0.673 0.327 0.000
I50 Heart failure
0.673 0.327 0.000
E28.3 Primary ovarian failure
0.673 0.327 0.000
S22.4 Multiple fractures of ribs
0.671 0.329 0.000
K04 Diseases of pulp and periapical tissues
0.671 0.329 0.000
J15.2 Pneumonia due to staphylococcus
0.670 0.330 0.000
J42 Unspecified chronic bronchitis
0.670 0.330 0.000
Z02.9 Examination for administrative purposes, unspecified
0.669 0.330 0.000
Z02.7 Issue of medical certificate
0.669 0.330 0.000
Z02.6 Examination for insurance purposes
0.669 0.330 0.000
Z02.5 Examination for participation in sport
0.669 0.330 0.000
Z02.4 Examination for driving licence
0.669 0.330 0.000
Z02.3 Examination for recruitment to armed forces
0.669 0.330 0.000
Z02.2 Examination for admission to residential institution
0.669 0.330 0.000
Z02.1 Pre-employment examination
0.669 0.330 0.000
Z02.0 Examination for admission to educational institution
0.669 0.330 0.000
K36 Other appendicitis
0.669 0.331 0.000
K92 Other diseases of digestive system
0.667 0.333 0.000
J84.8 Other specified interstitial pulmonary diseases
0.667 0.333 0.000
J18.1 Lobar pneumonia, unspecified
0.667 0.333 0.000
I77 Other disorders of arteries and arterioles
0.667 0.333 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.666 0.334 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.666 0.334 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.666 0.334 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.666 0.334 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.666 0.334 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.666 0.334 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.666 0.334 0.000
J95-J99 Other diseases of the respiratory system
0.666 0.334 0.000
E28.2 Polycystic ovarian syndrome
0.666 0.334 0.000
J18.8 Other pneumonia, organism unspecified
0.665 0.335 0.000
J18.2 Hypostatic pneumonia, unspecified
0.665 0.335 0.000
Z50.6 Orthoptic training
0.665 0.335 0.000
Z50.3 Drug rehabilitation
0.665 0.335 0.000
K29.6 Other gastritis
0.665 0.335 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.665 0.335 0.000
I44 Atrioventricular and left bundle-branch block
0.664 0.336 0.000
I73.8 Other specified peripheral vascular diseases
0.663 0.337 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.663 0.337 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.659 0.341 0.000
E11.8 With unspecified complications
0.659 0.341 0.000
E11.7 With multiple complications
0.659 0.341 0.000
E11.6 With other specified complications
0.659 0.341 0.000
E11.0 With coma
0.659 0.341 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.658 0.342 0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.658 0.342 0.000
K26.2 Acute with both haemorrhage and perforation
0.658 0.342 0.000
K26.1 Acute with perforation
0.658 0.342 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.657 0.342 0.000
E32 Diseases of thymus
0.657 0.342 0.000
E31 Polyglandular dysfunction
0.657 0.342 0.000
E30 Disorders of puberty, not elsewhere classified
0.657 0.342 0.000
E25 Adrenogenital disorders
0.657 0.342 0.000
E22 Hyperfunction of pituitary gland
0.657 0.342 0.000
E20 Hypoparathyroidism
0.657 0.342 0.000
E40-E46 Malnutrition
0.657 0.343 0.000
I61 Intracerebral haemorrhage
0.656 0.344 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.655 0.345 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.655 0.345 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.655 0.345 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.655 0.345 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.655 0.345 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.655 0.345 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.655 0.345 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.655 0.345 0.000
T36 Poisoning by systemic antibiotics
0.655 0.345 0.000
I20.1 Angina pectoris with documented spasm
0.654 0.345 0.000
J93.1 Other spontaneous pneumothorax
0.654 0.345 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.654 0.346 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.653 0.347 0.000
J14 Pneumonia due to Haemophilus influenzae
0.652 0.347 0.000
F80-F89 Disorders of psychological development
0.652 0.348 0.000
H10-H13 Disorders of conjunctiva
0.652 0.348 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.651 0.349 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.650 0.350 0.000
Q35-Q37 Cleft lip and cleft palate
0.650 0.350 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.650 0.350 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.650 0.350 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.650 0.350 0.000
I23 Certain current complications following acute myocardial infarction
0.650 0.350 0.000
Z13.5 Special screening examination for eye and ear disorders
0.649 0.351 0.000
A87 Viral meningitis
0.649 0.351 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.648 0.352 0.000
I51.8 Other ill-defined heart diseases
0.646 0.354 0.000
B97.6 Parvovirus as the cause of diseases classified to other chapters
0.645 0.354 0.000
B97.5 Reovirus as the cause of diseases classified to other chapters
0.645 0.354 0.000
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters
0.645 0.354 0.000
B97.3 Retrovirus as the cause of diseases classified to other chapters
0.645 0.354 0.000
B97.2 Coronavirus as the cause of diseases classified to other chapters
0.645 0.354 0.000
B97.1 Enterovirus as the cause of diseases classified to other chapters
0.645 0.354 0.000
B97.0 Adenovirus as the cause of diseases classified to other chapters
0.645 0.354 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.646 0.354 0.000
K38 Other diseases of appendix
0.645 0.355 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.644 0.356 0.000
I78 Diseases of capillaries
0.644 0.356 0.000
E29 Testicular dysfunction
0.643 0.357 0.000
Z63.9 Problem related to primary support group, unspecified
0.642 0.358 0.000
Z63.8 Other specified problems related to primary support group
0.642 0.358 0.000
Z63.6 Dependent relative needing care at home
0.642 0.358 0.000
Z63.5 Disruption of family by separation and divorce
0.642 0.358 0.000
Z63.3 Absence of family member
0.642 0.358 0.000
Z63.2 Inadequate family support
0.642 0.358 0.000
Z63.1 Problems in relationship with parents and in-laws
0.642 0.358 0.000
J94.2 Haemothorax
0.642 0.358 0.000
D80 Immunodeficiency with predominantly antibody defects
0.641 0.359 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.639 0.360 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.639 0.361 0.000
S40-S49 Injuries to the shoulder and upper arm
0.639 0.361 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.639 0.361 0.000
J93.0 Spontaneous tension pneumothorax
0.638 0.361 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.638 0.362 0.000
F60.9 Personality disorder, unspecified
0.638 0.362 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.637 0.363 0.000
K22.7 Barrett's oesophagus
0.637 0.363 0.000
T43.9 Psychotropic drug, unspecified
0.637 0.363 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.637 0.363 0.000
T43.6 Psychostimulants with abuse potential
0.637 0.363 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.637 0.363 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.637 0.363 0.000
T51 Toxic effect of alcohol
0.635 0.365 0.000
K09.8 Other cysts of oral region, not elsewhere classified
0.634 0.366 0.000
A48 Other bacterial diseases, not elsewhere classified
0.634 0.366 0.000
A44 Bartonellosis
0.634 0.366 0.000
A43 Nocardiosis
0.634 0.366 0.000
A42 Actinomycosis
0.634 0.366 0.000
A39 Meningococcal infection
0.634 0.366 0.000
A37 Whooping cough
0.634 0.366 0.000
A36 Diphtheria
0.634 0.366 0.000
A32 Listeriosis
0.634 0.366 0.000
A31 Infection due to other mycobacteria
0.634 0.366 0.000
A30 Leprosy [Hansen's disease]
0.634 0.366 0.000
A38 Scarlet fever
0.634 0.366 0.000
A35 Other tetanus
0.634 0.366 0.000
A34 Obstetrical tetanus
0.634 0.366 0.000
A33 Tetanus neonatorum
0.634 0.366 0.000
S22.40 Multiple fractures of ribs (closed)
0.632 0.368 0.000
B91 Sequelae of poliomyelitis
0.631 0.369 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.629 0.370 0.000
E00 Congenital iodine-deficiency syndrome
0.629 0.370 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.629 0.370 0.000
S62.3 Fracture of other metacarpal bone
0.629 0.371 0.000
Z04.6 General psychiatric examination, requested by authority
0.628 0.372 0.000
Z04.5 Examination and observation following other inflicted injury
0.628 0.372 0.000
Z04.4 Examination and observation following alleged rape and seduction
0.628 0.372 0.000
Z04.2 Examination and observation following work accident
0.628 0.372 0.000
Z04.0 Blood-alcohol and blood-drug test
0.628 0.372 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.628 0.372 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.628 0.372 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.628 0.372 0.000
I65.2 Occlusion and stenosis of carotid artery
0.628 0.372 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.627 0.373 0.000
A02 Other Salmonella infections
0.627 0.373 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.627 0.373 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.627 0.373 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.627 0.373 0.000
Z13.2 Special screening examination for nutritional disorders
0.627 0.373 0.000
I27 Other pulmonary heart diseases
0.626 0.373 0.000
Chapter VIII Diseases of the ear and mastoid process
0.625 0.375 0.000
E23 Hypofunction and other disorders of pituitary gland
0.624 0.376 0.000
Z50.2 Alcohol rehabilitation
0.624 0.376 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.623 0.377 0.000
B37 Candidiasis
0.623 0.377 0.000
Z22 Carrier of infectious disease
0.622 0.378 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.621 0.379 0.000
Z58.1 Exposure to air pollution
0.621 0.379 0.000
I46 Cardiac arrest
0.620 0.380 0.000
T56 Toxic effect of metals
0.620 0.380 0.000
S67 Crushing injury of wrist and hand
0.619 0.381 0.000
I05-I09 Chronic rheumatic heart diseases
0.619 0.381 0.000
K82 Other diseases of gallbladder
0.618 0.382 0.000
Z46.9 Fitting and adjustment of other unspecified device
0.618 0.382 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.618 0.382 0.000
Z46.4 Fitting and adjustment of orthodontic device
0.618 0.382 0.000
Z46.3 Fitting and adjustment of dental prosthetic device
0.618 0.382 0.000
Z46.1 Fitting and adjustment of hearing aid
0.618 0.382 0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses
0.618 0.382 0.000
D68 Other coagulation defects
0.618 0.382 0.000
E14.8 With unspecified complications
0.617 0.382 0.000
E14.7 With multiple complications
0.617 0.382 0.000
E14.6 With other specified complications
0.617 0.382 0.000
E14.5 With peripheral circulatory complications
0.617 0.382 0.000
E14.4 With neurological complications
0.617 0.382 0.000
E14.2 Withrenal complications
0.617 0.382 0.000
E14.1 With ketoacidosis
0.617 0.382 0.000
E14.0 With coma
0.617 0.382 0.000
Z46.8 Fitting and adjustment of other specified devices
0.617 0.382 0.000
I62.1 Nontraumatic extradural haemorrhage
0.617 0.383 0.000
T79-T79 Certain early complications of trauma
0.617 0.383 0.000
I67.1 Cerebral aneurysm, nonruptured
0.616 0.384 0.000
K26.4 Chronic or unspecified with haemorrhage
0.616 0.384 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.615 0.385 0.000
B99 Other and unspecified infectious diseases
0.615 0.385 0.000
Q21 Congenital malformations of cardiac septa
0.614 0.386 0.000
Q82 Other congenital malformations of skin
0.613 0.387 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.613 0.387 0.000
F70-F79 Mental retardation
0.613 0.387 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.612 0.388 0.000
S26 Injury of heart
0.612 0.388 0.000
S25 Injury of blood vessels of thorax
0.612 0.388 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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