TreeWAS – Variant ID: rs12493607

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.925	0.075
T43.2 Other and unspecified antidepressants	0.000	0.952	0.048
S52.50 Fracture of lower end of radius (closed)	0.047	0.953	0.000
S52.5 Fracture of lower end of radius	0.039	0.961	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.963	0.037
S52.51 Fracture of lower end of radius (open)	0.037	0.963	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.966	0.034
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.969	0.031
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.970	0.030
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.972	0.028
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.972	0.028
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.972	0.028
T43.9 Psychotropic drug, unspecified	0.000	0.973	0.027
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.973	0.027
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.973	0.027
T43.6 Psychostimulants with abuse potential	0.000	0.973	0.027
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.974	0.026
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.975	0.025
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.976	0.024
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.978	0.022
T45.0 Antiallergic and antiemetic drugs	0.000	0.978	0.022
T39.4 Antirheumatics, not elsewhere classified	0.000	0.978	0.022
T39.2 Pyrazolone derivatives	0.000	0.978	0.022
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.979	0.021
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.979	0.020
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.980	0.020
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.980	0.020
T45.5 Anticoagulants	0.000	0.980	0.020
T39.1 4-Aminophenol derivatives	0.000	0.980	0.020
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.980	0.020
T45.2 Vitamins, not elsewhere classified	0.000	0.981	0.019
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.981	0.019
T50.8 Diagnostic agents	0.000	0.981	0.019
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.982	0.018
T36 Poisoning by systemic antibiotics	0.000	0.982	0.018
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.982	0.018
T45.8 Other primarily systemic and haematological agents	0.000	0.982	0.018
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.982	0.018
T45.6 Fibrinolysis-affecting drugs	0.000	0.982	0.018
T45.4 Iron and its compounds	0.000	0.982	0.018
T45.3 Enzymes, not elsewhere classified	0.000	0.982	0.018
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.982	0.018
T50.7 Analeptics and opioid receptor antagonists	0.000	0.982	0.018
T50.5 Appetite depressants	0.000	0.982	0.018
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.982	0.018
T50.1 Loop [high-ceiling] diuretics	0.000	0.982	0.018
T50.0 Mineralocorticoids and their antagonists	0.000	0.982	0.018
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.983	0.017
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.983	0.017
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.983	0.017
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.983	0.017
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.983	0.017
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.983	0.017
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.984	0.016
T50.4 Drugs affecting uric acid metabolism	0.000	0.984	0.016
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.984	0.016
S52 Fracture of forearm	0.016	0.984	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.984	0.016
T39.0 Salicylates	0.000	0.984	0.015
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.985	0.015
T37.5 Antiviral drugs	0.000	0.985	0.015
T37.4 Anthelminthics	0.000	0.985	0.015
T37.3 Other antiprotozoal drugs	0.000	0.985	0.015
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.985	0.015
T37.1 Antimycobacterial drugs	0.000	0.985	0.015
T37.0 Sulphonamides	0.000	0.985	0.015
T41.5 Therapeutic gases	0.000	0.985	0.015
T41.4 Anaesthetic, unspecified	0.000	0.985	0.015
T41.3 Local anaesthetics	0.000	0.985	0.015
T41.2 Other and unspecified general anaesthetics	0.000	0.985	0.015
T41.1 Intravenous anaesthetics	0.000	0.985	0.015
T41.0 Inhaled anaesthetics	0.000	0.985	0.015
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.985	0.015
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.985	0.015
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.985	0.015
T46.7 Peripheral vasodilators	0.000	0.985	0.015
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.985	0.015
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.986	0.014
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.986	0.014
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.986	0.014
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.986	0.014
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.986	0.014
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.986	0.014
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.986	0.014
T44.0 Anticholinesterase agents	0.000	0.986	0.014
T49.9 Topical agent, unspecified	0.000	0.986	0.014
T49.8 Other topical agents	0.000	0.986	0.014
T49.7 Dental drugs, topically applied	0.000	0.986	0.014
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.986	0.014
T49.5 Ophthalmological drugs and preparations	0.000	0.986	0.014
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.986	0.014
T49.3 Emollients, demulcents and protectants	0.000	0.986	0.014
T49.2 Local astringents and local detergents	0.000	0.986	0.014
T49.1 Antipruritics	0.000	0.986	0.014
T46.1 Calcium-channel blockers	0.000	0.986	0.013
S52.8 Fracture of other parts of forearm	0.013	0.986	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.987	0.013
T48.4 Expectorants	0.000	0.987	0.013
T48.3 Antitussives	0.000	0.987	0.013
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.987	0.013
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.987	0.013
T48.0 Oxytocic drugs	0.000	0.987	0.013
T36.0 Penicillins	0.000	0.987	0.013
T36.9 Systemic antibiotic, unspecified	0.000	0.987	0.013
T36.7 Antifungal antibiotics, systemically used	0.000	0.987	0.013
T36.6 Rifamycins	0.000	0.987	0.013
T36.5 Aminoglycosides	0.000	0.987	0.013
T36.4 Tetracyclines	0.000	0.987	0.013
T36.2 Chloramphenicol group	0.000	0.987	0.013
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.987	0.013
T48.5 Anti-common-cold drugs	0.000	0.987	0.013
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.987	0.013
S52.2 Fracture of shaft of ulna	0.013	0.987	0.000
G20 Parkinson's disease	0.013	0.987	0.000
T36.3 Macrolides	0.000	0.987	0.013
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.988	0.012
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.988	0.012
T47.7 Emetics	0.000	0.988	0.012
T47.6 Antidiarrhoeal drugs	0.000	0.988	0.012
T47.5 Digestants	0.000	0.988	0.012
T47.4 Other laxatives	0.000	0.988	0.012
T47.3 Saline and osmotic laxatives	0.000	0.988	0.012
T36.8 Other systemic antibiotics	0.000	0.988	0.012
S52.7 Multiple fractures of forearm	0.012	0.988	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.988	0.012
S52.9 Fracture of forearm, part unspecified	0.012	0.988	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.988	0.012
S52.80 Fracture of other parts of forearm (closed)	0.012	0.988	0.000
T42.0 Hydantoin derivatives	0.000	0.988	0.011
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.988	0.011
T47.2 Stimulant laxatives	0.000	0.989	0.011
S52.4 Fracture of shafts of both ulna and radius	0.011	0.989	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.989	0.011
S52.20 Fracture of shaft of ulna (closed)	0.011	0.989	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.989	0.011
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.989	0.011
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.989	0.011
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.989	0.011
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.989	0.011
T42.3 Barbiturates	0.000	0.989	0.011
T42.2 Succinimides and oxazolidinediones	0.000	0.989	0.011
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.989	0.011
T47.0 Histamine H(2)-receptor antagonists	0.000	0.989	0.010
S52.6 Fracture of lower end of both ulna and radius	0.011	0.989	0.000
T42.4 Benzodiazepines	0.000	0.989	0.011
S52.71 Multiple fractures of forearm (open)	0.010	0.990	0.000
S52.81 Fracture of other parts of forearm (open)	0.010	0.990	0.000
S50-S59 Injuries to the elbow and forearm	0.010	0.990	0.000
S52.1 Fracture of upper end of radius	0.009	0.990	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.990	0.009
S52.3 Fracture of shaft of radius	0.009	0.991	0.000
S52.21 Fracture of shaft of ulna (open)	0.009	0.991	0.000
S59 Other and unspecified injuries of forearm	0.009	0.991	0.000
R52.2 Other chronic pain	0.000	0.991	0.009
S52.91 Fracture of forearm, part unspecified (open)	0.009	0.991	0.000
S52.90 Fracture of forearm, part unspecified (closed)	0.009	0.991	0.000
T40.2 Other opioids	0.000	0.991	0.009
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.991	0.008
T40.8 Lysergide [LSD]	0.000	0.991	0.008
T40.7 Cannabis (derivatives)	0.000	0.991	0.008
T40.3 Methadone	0.000	0.991	0.008
T40.1 Heroin	0.000	0.991	0.008
T40.0 Opium	0.000	0.991	0.008
S59.9 Unspecified injury of forearm	0.008	0.991	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.992	0.008
S52.41 Fracture of shafts of both ulna and radius (open)	0.008	0.992	0.000
S56 Injury of muscle and tendon at forearm level	0.008	0.992	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.008	0.992	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.992	0.008
T38.7 Androgens and anabolic congeners	0.000	0.992	0.008
T38.5 Other oestrogens and progestogens	0.000	0.992	0.008
T38.4 Oral contraceptives	0.000	0.992	0.008
T38.2 Antithyroid drugs	0.000	0.992	0.008
T38.0 Glucocorticoids and synthetic analogues	0.000	0.992	0.008
E87.7 Fluid overload	0.000	0.992	0.008
S52.0 Fracture of upper end of ulna	0.008	0.992	0.000
T40.5 Cocaine	0.000	0.992	0.008
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.008	0.992	0.000
T38.1 Thyroid hormones and substitutes	0.000	0.992	0.008
S52.40 Fracture of shafts of both ulna and radius (closed)	0.008	0.992	0.000
S54 Injury of nerves at forearm level	0.008	0.992	0.000
E87.3 Alkalosis	0.000	0.992	0.008
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.007	0.992	0.000
W13.9 Unspecified place	0.000	0.993	0.007
S58 Traumatic amputation of forearm	0.007	0.993	0.000
S57 Crushing injury of forearm	0.007	0.993	0.000
S55 Injury of blood vessels at forearm level	0.007	0.993	0.000
R63.0 Anorexia	0.007	0.993	0.000
Q18.1 Preauricular sinus and cyst	0.007	0.993	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.993	0.007
M25.78 Osteophyte (Other)	0.000	0.993	0.007
S52.11 Fracture of upper end of radius (open)	0.007	0.993	0.000
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.007	0.993	0.000
S52.31 Fracture of shaft of radius (open)	0.007	0.993	0.000
E87.0 Hyperosmolality and hypernatraemia	0.000	0.993	0.007
S59.8 Other specified injuries of forearm	0.007	0.993	0.000
S59.7 Multiple injuries of forearm	0.007	0.993	0.000
S51 Open wound of forearm	0.007	0.993	0.000
S54.0 Injury of ulnar nerve at forearm level	0.007	0.993	0.000
Q89.2 Congenital malformations of other endocrine glands	0.007	0.993	0.000
Q18 Other congenital malformations of face and neck	0.006	0.993	0.000
S52.70 Multiple fractures of forearm (closed)	0.006	0.993	0.000
K09.0 Developmental odontogenic cysts	0.000	0.993	0.007
Q63.0 Accessory kidney	0.007	0.993	0.000
S53.4 Sprain and strain of elbow	0.006	0.994	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.006	0.994	0.000
Z11.2 Special screening examination for other bacterial diseases	0.000	0.994	0.006
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.001	0.994	0.006
S56.7 Injury of multiple muscles and tendons at forearm level	0.006	0.994	0.000
T42.1 Iminostilbenes	0.000	0.994	0.006
E87.4 Mixed disorder of acid-base balance	0.000	0.994	0.006
S53.3 Traumatic rupture of ulnar collateral ligament	0.006	0.994	0.000
S56.2 Injury of other flexor muscle and tendon at forearm level	0.006	0.994	0.000
S56.0 Injury of flexor muscle and tendon of thumb at forearm level	0.006	0.994	0.000
Q89 Other congenital malformations, not elsewhere classified	0.006	0.994	0.000
Q80-Q89 Other congenital malformations	0.006	0.994	0.000
S56.5 Injury of other extensor muscle and tendon at forearm level	0.006	0.994	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.006	0.994	0.000
Q63 Other congenital malformations of kidney	0.006	0.994	0.000
T40.6 Other and unspecified narcotics	0.000	0.994	0.006
S52.61 Fracture of lower end of both ulna and radius (open)	0.006	0.994	0.000
S53.1 Dislocation of elbow, unspecified	0.006	0.994	0.000
S53.2 Traumatic rupture of radial collateral ligament	0.006	0.994	0.000
S53.0 Dislocation of radial head	0.006	0.994	0.000
S54.2 Injury of radial nerve at forearm level	0.006	0.994	0.000
S54.9 Injury of unspecified nerve at forearm level	0.006	0.994	0.000
S54.8 Injury of other nerves at forearm level	0.006	0.994	0.000
S54.7 Injury of multiple nerves at forearm level	0.006	0.994	0.000
S54.3 Injury of cutaneous sensory nerve at forearm level	0.006	0.994	0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.006	0.994	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.000	0.994	0.006
W08.0 Home	0.006	0.994	0.000
Q74.1 Congenital malformation of knee	0.006	0.994	0.000
G20-G26 Extrapyramidal and movement disorders	0.006	0.994	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.006	0.994	0.000
S51.8 Open wound of other parts of forearm	0.006	0.994	0.000
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.005	0.994	0.000
S54.1 Injury of median nerve at forearm level	0.005	0.994	0.000
S55.9 Injury of unspecified blood vessel at forearm level	0.005	0.994	0.000
S55.8 Injury of other blood vessels at forearm level	0.005	0.994	0.000
S55.7 Injury of multiple blood vessels at forearm level	0.005	0.994	0.000
S55.2 Injury of vein at forearm level	0.005	0.994	0.000
S55.1 Injury of radial artery at forearm level	0.005	0.994	0.000
S55.0 Injury of ulnar artery at forearm level	0.005	0.994	0.000
S57.9 Crushing injury of forearm, part unspecified	0.005	0.994	0.000
S57.8 Crushing injury of forearm, part unspecified	0.005	0.994	0.000
S57.7 Crushing injury of other parts of forearm	0.005	0.994	0.000
S57.0 Crushing injury of elbow	0.005	0.994	0.000
S58.9 Traumatic amputation of forearm, level unspecified	0.005	0.994	0.000
S58.1 Traumatic amputation at level between elbow and wrist	0.005	0.994	0.000
S58.0 Traumatic amputation at elbow level	0.005	0.994	0.000
Q60-Q64 Congenital malformations of the urinary system	0.006	0.994	0.000
Q74 Other congenital malformations of limb(s)	0.005	0.995	0.000
Q12 Congenital lens malformations	0.005	0.995	0.000
T40.4 Other synthetic narcotics	0.000	0.995	0.005
Q14 Congenital malformations of posterior segment of eye	0.005	0.995	0.000
C06.2 Retromolar area	0.005	0.995	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.001	0.995	0.005
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.995	0.005
K09.2 Other cysts of jaw	0.000	0.995	0.005
K09 Cysts of oral region, not elsewhere classified	0.000	0.995	0.005
C06 Malignant neoplasm of other and unspecified parts of mouth	0.005	0.995	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.005	0.995	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.005	0.995	0.000
S51.9 Open wound of forearm, part unspecified	0.005	0.995	0.000
C04 Malignant neoplasm of floor of mouth	0.005	0.995	0.000
C04.9 Floor of mouth, unspecified	0.005	0.995	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.005	0.995	0.000
Q50-Q56 Congenital malformations of genital organs	0.005	0.995	0.000
Q85 Phakomatoses, not elsewhere classified	0.005	0.995	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.005	0.995	0.000
S52.01 Fracture of upper end of ulna (open)	0.005	0.995	0.000
Q18.9 Congenital malformation of face and neck, unspecified	0.005	0.995	0.000
Q18.8 Other specified congenital malformations of face and neck	0.005	0.995	0.000
Q18.7 Microcheilia	0.005	0.995	0.000
Q18.6 Macrocheilia	0.005	0.995	0.000
Q18.5 Microstomia	0.005	0.995	0.000
Q18.4 Macrostomia	0.005	0.995	0.000
Q18.3 Webbing of neck	0.005	0.995	0.000
Q18.2 Other branchial cleft malformations	0.005	0.995	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.005	0.995	0.000
Q15 Other congenital malformations of eye	0.005	0.995	0.000
W50.9 Unspecified place	0.000	0.995	0.005
Q16 Congenital malformations of ear causing impairment of hearing	0.005	0.995	0.000
Q13 Congenital malformations of anterior segment of eye	0.005	0.995	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.005	0.995	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.005	0.995	0.000
Q17 Other congenital malformations of ear	0.005	0.995	0.000
Q76 Congenital malformations of spine and bony thorax	0.005	0.995	0.000
Q83 Congenital malformations of breast	0.005	0.995	0.000
M00.9 Pyogenic arthritis, unspecified	0.005	0.995	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.005	0.995	0.000
S56.20 Unspecified injury of other flexor muscle, fascia and tendon at forearm level	0.005	0.995	0.000
Q63.2 Ectopic kidney	0.005	0.995	0.000
Q89.9 Congenital malformation, unspecified	0.005	0.995	0.000
Q89.8 Other specified congenital malformations	0.005	0.995	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.005	0.995	0.000
Q89.4 Conjoined twins	0.005	0.995	0.000
Q89.3 Situs inversus	0.005	0.995	0.000
Q89.1 Congenital malformations of adrenal gland	0.005	0.995	0.000
Q89.0 Congenital malformations of spleen	0.005	0.995	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.005	0.995	0.000
Q12.0 Congenital cataract	0.005	0.995	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.005	0.995	0.000
R52.0 Acute pain	0.000	0.995	0.005
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.005	0.995	0.000
Q84 Other congenital malformations of integument	0.005	0.995	0.000
Q81 Epidermolysis bullosa	0.005	0.995	0.000
Q80 Congenital ichthyosis	0.005	0.995	0.000
Q35-Q37 Cleft lip and cleft palate	0.005	0.995	0.000
S52.10 Fracture of upper end of radius (closed)	0.005	0.995	0.000
G21 Secondary Parkinsonism	0.005	0.995	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.005	0.995	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.005	0.995	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.004	0.995	0.000
Q63.8 Other specified congenital malformations of kidney	0.004	0.995	0.000
Q63.3 Hyperplastic and giant kidney	0.004	0.995	0.000
C06.9 Mouth, unspecified	0.005	0.995	0.000
S53.11 Anterior subluxation and dislocation of ulnohumeral joint	0.004	0.995	0.000
S53.10 Unspecified subluxation and dislocation of ulnohumeral joint	0.004	0.995	0.000
S52.30 Fracture of shaft of radius (closed)	0.004	0.995	0.001
C04.0 Anterior floor of mouth	0.005	0.995	0.000
Q77.4 Achondroplasia	0.004	0.995	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.004	0.995	0.000
Q14.1 Congenital malformation of retina	0.004	0.995	0.000
C05 Malignant neoplasm of palate	0.004	0.995	0.000
S54.20 Injury of radial nerve at forearm level, unspecified arm	0.004	0.995	0.000
S51.0 Open wound of elbow	0.004	0.995	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.004	0.995	0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.004	0.995	0.000
K09.9 Cyst of oral region, unspecified	0.000	0.995	0.004
G23 Other degenerative diseases of basal ganglia	0.004	0.996	0.000
C05.1 Soft palate	0.004	0.996	0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.004	0.996	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.004	0.996	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.004	0.996	0.000
G22 Parkinsonism in diseases classified elsewhere	0.004	0.996	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.004	0.996	0.000
Q70 Syndactyly	0.004	0.996	0.000
Q55 Other congenital malformations of male genital organs	0.004	0.996	0.000
Q54 Hypospadias	0.004	0.996	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.004	0.996	0.000
Q83.1 Accessory breast	0.004	0.996	0.000
Q75 Other congenital malformations of skull and face bones	0.004	0.996	0.000
Q73 Reduction defects of unspecified limb	0.004	0.996	0.000
Q72 Reduction defects of lower limb	0.004	0.996	0.000
Q71 Reduction defects of upper limb	0.004	0.996	0.000
Q69 Polydactyly	0.004	0.996	0.000
Q00-Q07 Congenital malformations of the nervous system	0.004	0.996	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.004	0.996	0.000
Q51 Congenital malformations of uterus and cervix	0.004	0.996	0.000
Q68 Other congenital musculoskeletal deformities	0.004	0.996	0.000
R52 Pain, not elsewhere classified	0.000	0.996	0.004
Q67.6 Pectus excavatum	0.004	0.996	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.004	0.996	0.000
G24 Dystonia	0.004	0.996	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.004	0.996	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.004	0.996	0.000
Q74.3 Arthrogryposis multiplex congenita	0.004	0.996	0.000
Q12.9 Congenital lens malformation, unspecified	0.004	0.996	0.000
Q12.8 Other congenital lens malformations	0.004	0.996	0.000
Q12.4 Spherophakia	0.004	0.996	0.000
Q12.3 Congenital aphakia	0.004	0.996	0.000
Q12.2 Coloboma of lens	0.004	0.996	0.000
Q12.1 Congenital displaced lens	0.004	0.996	0.000
Z98.1 Arthrodesis status	0.004	0.996	0.000
Q65 Congenital deformities of hip	0.004	0.996	0.000
M00.94 Pyogenic arthritis, unspecified (Hand)	0.004	0.996	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.004	0.996	0.000
Q78 Other osteochondrodysplasias	0.004	0.996	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.004	0.996	0.000
C09 Malignant neoplasm of tonsil	0.004	0.996	0.000
S50 Superficial injury of forearm	0.004	0.996	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.000	0.996	0.004
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.004	0.996	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.004	0.996	0.000
Q14.3 Congenital malformation of choroid	0.004	0.996	0.000
Q14.2 Congenital malformation of optic disk	0.004	0.996	0.000
Q14.0 Congenital malformation of vitreous humour	0.004	0.996	0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.000	0.996	0.004
Q64 Other congenital malformations of urinary system	0.004	0.996	0.000
Q31 Congenital malformations of larynx	0.004	0.996	0.000
S52.00 Fracture of upper end of ulna (closed)	0.004	0.996	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.004	0.996	0.000
C02.1 Border of tongue	0.004	0.996	0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.004	0.996	0.000
C06.1 Vestibule of mouth	0.004	0.996	0.000
Q30 Congenital malformations of nose	0.004	0.996	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.000	0.996	0.004
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.004	0.996	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.004	0.996	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.004	0.996	0.000
G21.9 Secondary Parkinsonism, unspecified	0.004	0.996	0.000
G25 Other extrapyramidal and movement disorders	0.004	0.996	0.000
Q43 Other congenital malformations of intestine	0.004	0.996	0.000
C04.8 Overlapping lesion of floor of mouth	0.004	0.996	0.000
C04.1 Lateral floor of mouth	0.004	0.996	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.004	0.996	0.000
C06.0 Cheek mucosa	0.004	0.996	0.000
Q85.1 Tuberous sclerosis	0.004	0.996	0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.004	0.996	0.000
C13 Malignant neoplasm of hypopharynx	0.004	0.996	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.996	0.004
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.004	0.996	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.004	0.996	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.004	0.996	0.000
Q77.6 Chondroectodermal dysplasia	0.004	0.996	0.000
Q77.5 Diastrophic dysplasia	0.004	0.996	0.000
Q77.3 Chondrodysplasia punctata	0.004	0.996	0.000
Q77.2 Short rib syndrome	0.004	0.996	0.000
Q77.1 Thanatophoric short stature	0.004	0.996	0.000
Q77.0 Achondrogenesis	0.004	0.996	0.000
S51.7 Multiple open wounds of forearm	0.004	0.996	0.000
Q96 Turner's syndrome	0.004	0.996	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.996	0.004
Q15.0 Congenital glaucoma	0.004	0.996	0.000
Q34 Other congenital malformations of respiratory system	0.004	0.996	0.000
Q33 Congenital malformations of lung	0.004	0.996	0.000
Q32 Congenital malformations of trachea and bronchus	0.004	0.996	0.000
Q15.9 Congenital malformation of eye, unspecified	0.004	0.996	0.000
Q15.8 Other specified congenital malformations of eye	0.004	0.996	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.004	0.996	0.000
Q11.3 Macrophthalmos	0.004	0.996	0.000
Q11.2 Microphthalmos	0.004	0.996	0.000
Q11.1 Other anophthalmos	0.004	0.996	0.000
Q11.0 Cystic eyeball	0.004	0.996	0.000
Q13.9 Congenital malformation of anterior segment of eye, unspecified	0.004	0.996	0.000
Q13.8 Other congenital malformations of anterior segment of eye	0.004	0.996	0.000
Q13.5 Blue sclera	0.004	0.996	0.000
Q13.4 Other congenital corneal malformations	0.004	0.996	0.000
Q13.3 Congenital corneal opacity	0.004	0.996	0.000
Q13.2 Other congenital malformations of iris	0.004	0.996	0.000
Q13.1 Absence of iris	0.004	0.996	0.000
Q13.0 Coloboma of iris	0.004	0.996	0.000
Q16.9 Congenital malformation of ear causing impairment of hearing, unspecified	0.004	0.996	0.000
Q16.5 Congenital malformation of inner ear	0.004	0.996	0.000
Q16.4 Other congenital malformations of middle ear	0.004	0.996	0.000
Q16.3 Congenital malformation of ear ossicles	0.004	0.996	0.000
Q16.2 Absence of eustachian tube	0.004	0.996	0.000
Q16.1 Congenital absence, atresia and stricture of auditory canal (external)	0.004	0.996	0.000
Q16.0 Congenital absence of (ear) auricle	0.004	0.996	0.000
Q62.1 Atresia and stenosis of ureter	0.004	0.996	0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.004	0.996	0.000
Q43.8 Other specified congenital malformations of intestine	0.004	0.996	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.996	0.004
E87.6 Hypokalaemia	0.000	0.996	0.004
Q17.9 Congenital malformation of ear, unspecified	0.004	0.996	0.000
Q17.8 Other specified congenital malformations of ear	0.004	0.996	0.000
Q17.4 Misplaced ear	0.004	0.996	0.000
Q17.3 Other misshapen ear	0.004	0.996	0.000
Q17.2 Microtia	0.004	0.996	0.000
Q17.1 Macrotia	0.004	0.996	0.000
Q17.0 Accessory auricle	0.004	0.996	0.000
Q54.1 Hypospadias, penile	0.004	0.996	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.004	0.996	0.000
Q76.8 Other congenital malformations of bony thorax	0.004	0.996	0.000
Q76.7 Congenital malformation of sternum	0.004	0.996	0.000
Q76.6 Other congenital malformations of ribs	0.004	0.996	0.000
Q76.5 Cervical rib	0.004	0.996	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.004	0.996	0.000
Q76.2 Congenital spondylolisthesis	0.004	0.996	0.000
Q76.1 Klippel-Feil syndrome	0.004	0.996	0.000
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.004	0.996	0.000
M00.98 Pyogenic arthritis, unspecified (Other)	0.004	0.996	0.000
Q83.9 Congenital malformation of breast, unspecified	0.004	0.996	0.000
Q83.3 Accessory nipple	0.004	0.996	0.000
Q83.2 Absent nipple	0.004	0.996	0.000
Q83.0 Congenital absence of breast with absent nipple	0.004	0.996	0.000
Q85.9 Phakomatosis, unspecified	0.004	0.996	0.000
Q67.8 Other congenital deformities of chest	0.003	0.996	0.000
Q67.7 Pectus carinatum	0.003	0.996	0.000
Q67.3 Plagiocephaly	0.003	0.996	0.000
Q67.2 Dolichocephaly	0.003	0.996	0.000
Q67.1 Compression facies	0.003	0.996	0.000
Q67.0 Facial asymmetry	0.003	0.996	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.004	0.996	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.004	0.996	0.000
Q37 Cleft palate with cleft lip	0.004	0.996	0.000
Q17.5 Prominent ear	0.004	0.996	0.000
Q54.0 Hypospadias, balanic	0.004	0.996	0.000
Q82 Other congenital malformations of skin	0.004	0.996	0.000
Q10.7 Congenital malformation of orbit	0.003	0.996	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.003	0.996	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.003	0.996	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.003	0.996	0.000
Q10.3 Other congenital malformations of eyelid	0.003	0.996	0.000
Q10.2 Congenital entropion	0.003	0.996	0.000
Q10.1 Congenital ectropion	0.003	0.996	0.000
Q07 Other congenital malformations of nervous system	0.004	0.996	0.000
Q40 Other congenital malformations of upper alimentary tract	0.004	0.996	0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.004	0.996	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.004	0.996	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.004	0.996	0.000
Q76.0 Spina bifida occulta	0.004	0.996	0.000
C03 Malignant neoplasm of gum	0.004	0.996	0.000
Q55.6 Other congenital malformations of penis	0.004	0.996	0.000
Q80.9 Congenital ichthyosis, unspecified	0.003	0.996	0.000
Q80.8 Other congenital ichthyosis	0.003	0.996	0.000
Q80.4 Harlequin foetus	0.003	0.996	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.003	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations