TreeWAS – Variant ID: rs12493885

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	0.000	0.000	1.000
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.002	0.998
I24 Other acute ischaemic heart diseases	0.000	0.005	0.995
I20 Angina pectoris	0.000	0.006	0.994
I25.2 Old myocardial infarction	0.000	0.007	0.993
I20.0 Unstable angina	0.000	0.009	0.991
I24.8 Other forms of acute ischaemic heart disease	0.000	0.030	0.970
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.052	0.948
I20.9 Angina pectoris, unspecified	0.000	0.103	0.897
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.173	0.826
I23 Certain current complications following acute myocardial infarction	0.000	0.196	0.804
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.254	0.746
I21 Acute myocardial infarction	0.000	0.261	0.739
I22 Subsequent myocardial infarction	0.000	0.262	0.738
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I24.1 Dressler's syndrome	0.000	0.287	0.713
I25.3 Aneurysm of heart	0.000	0.290	0.710
I25.4 Coronary artery aneurysm	0.000	0.315	0.684
I21.9 Acute myocardial infarction, unspecified	0.000	0.317	0.683
I25.5 Ischaemic cardiomyopathy	0.000	0.323	0.677
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.327	0.673
I23.8 Other current complications following acute myocardial infarction	0.000	0.336	0.664
I20.8 Other forms of angina pectoris	0.000	0.342	0.658
I22.8 Subsequent myocardial infarction of other sites	0.000	0.371	0.629
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.416	0.584
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.423	0.577
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.423	0.577
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.423	0.577
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.423	0.577
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.423	0.577
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.423	0.577
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.423	0.577
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.435	0.565
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.462	0.538
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.470	0.530
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.481	0.519
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.553	0.447
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.575	0.425
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.618	0.382
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.656	0.344
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.657	0.343
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.667	0.333
Z95.1 Presence of aortocoronary bypass graft	0.000	0.669	0.331
Z95.4 Presence of other heart-valve replacement	0.000	0.702	0.298
Z95.3 Presence of xenogenic heart valve	0.000	0.716	0.284
I20.1 Angina pectoris with documented spasm	0.001	0.728	0.271
Z95.2 Presence of prosthetic heart valve	0.000	0.733	0.267
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.777	0.223
I21.4 Acute subendocardial myocardial infarction	0.000	0.808	0.192
Z95.0 Presence of cardiac pacemaker	0.000	0.839	0.161
R14 Flatulence and related conditions	0.000	0.987	0.013
T51.0 Ethanol	0.008	0.992	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.992	0.008
J39.2 Other diseases of pharynx	0.000	0.993	0.007
H11.3 Conjunctival haemorrhage	0.000	0.993	0.007
H11.0 Pterygium	0.000	0.993	0.007
H11 Other disorders of conjunctiva	0.000	0.993	0.007
H83.0 Labyrinthitis	0.000	0.994	0.006
H11.1 Conjunctival degenerations and deposits	0.000	0.994	0.006
S80.8 Other superficial injuries of lower leg	0.006	0.994	0.000
H11.9 Disorder of conjunctiva, unspecified	0.000	0.995	0.005
H11.2 Conjunctival scars	0.000	0.995	0.005
Z72.1 Alcohol use	0.000	0.995	0.005
T51 Toxic effect of alcohol	0.005	0.995	0.000
H11.8 Other specified disorders of conjunctiva	0.000	0.995	0.004
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.995	0.005
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.996	0.004
M89.0 Algoneurodystrophy	0.004	0.996	0.000
M89.8 Other specified disorders of bone	0.004	0.996	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.996	0.004
M89 Other disorders of bone	0.004	0.996	0.000
T51.9 Alcohol, unspecified	0.004	0.996	0.000
O14.9 Preeclampsia, unspecified	0.004	0.996	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.004	0.996	0.000
M89.03 Algoneurodystrophy (Forearm)	0.004	0.996	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.004	0.996	0.000
M89.84 Other specified disorders of bone (Hand)	0.004	0.996	0.000
M89.9 Disorder of bone, unspecified	0.004	0.996	0.000
T51.8 Other alcohols	0.003	0.996	0.000
T51.3 Fusel oil	0.003	0.996	0.000
T51.2 2-Propanol	0.003	0.996	0.000
T51.1 Methanol	0.003	0.996	0.000
Z80.4 Family history of malignant neoplasm of genital organs	0.000	0.996	0.004
M89.04 Algoneurodystrophy (Hand)	0.003	0.996	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.003	0.996	0.000
M19.0 Primary arthrosis of other joints	0.000	0.996	0.004
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.004	0.996	0.000
O14.1 Severe preeclampsia	0.003	0.997	0.000
L81.4 Other melanin hyperpigmentation	0.000	0.997	0.003
O14.0 Moderate preeclampsia	0.003	0.997	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.000	0.997	0.003
M89.09 Algoneurodystrophy (Site unspecified)	0.003	0.997	0.000
M89.3 Hypertrophy of bone	0.003	0.997	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.003	0.997	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.003	0.997	0.000
M89.08 Algoneurodystrophy (Other)	0.003	0.997	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.003	0.997	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.003	0.997	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.003	0.997	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.003	0.997	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.003	0.997	0.000
M89.5 Osteolysis	0.003	0.997	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.000	0.997	0.003
M89.89 Other specified disorders of bone (Site unspecified)	0.003	0.997	0.000
M89.83 Other specified disorders of bone (Forearm)	0.003	0.997	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.003	0.997	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.003	0.997	0.000
S80 Superficial injury of lower leg	0.003	0.997	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.997	0.003
M89.81 Other specified disorders of bone (Shoulder region)	0.003	0.997	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.003	0.997	0.000
M89.6 Osteopathy after poliomyelitis	0.003	0.997	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.003	0.997	0.000
M89.2 Other disorders of bone development and growth	0.003	0.997	0.000
M89.1 Epiphyseal arrest	0.003	0.997	0.000
H83 Other diseases of inner ear	0.000	0.997	0.003
M89.96 Disorder of bone, unspecified (Lower leg)	0.003	0.997	0.000
Z13.6 Special screening examination for cardiovascular disorders	0.003	0.997	0.000
S80.0 Contusion of knee	0.003	0.997	0.000
S80.7 Multiple superficial injuries of lower leg	0.003	0.997	0.000
M89.88 Other specified disorders of bone (Other)	0.003	0.997	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.000	0.997	0.003
M89.37 Hypertrophy of bone (Ankle and foot)	0.003	0.997	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.003	0.997	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.003	0.997	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.003	0.997	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.003	0.997	0.000
T88.5 Other complications of anaesthesia	0.003	0.997	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.003	0.997	0.000
I83 Varicose veins of lower extremities	0.000	0.997	0.003
T78.2 Anaphylactic shock, unspecified	0.003	0.997	0.000
M19.08 Primary arthrosis of other joints (Other)	0.000	0.997	0.003
M19.06 Primary arthrosis of other joints-Lower leg	0.000	0.997	0.003
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.000	0.997	0.003
M89.94 Disorder of bone, unspecified (Hand)	0.003	0.997	0.000
O14.2 HELLP syndrome	0.003	0.997	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
B37.8 Candidiasis of other sites	0.003	0.997	0.000
H10-H13 Disorders of conjunctiva	0.000	0.997	0.003
M89.55 Osteolysis (Pelvic region and thigh)	0.003	0.997	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.002	0.997	0.000
M89.38 Hypertrophy of bone (Other)	0.002	0.997	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.002	0.997	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.002	0.997	0.000
M89.34 Hypertrophy of bone (Hand)	0.002	0.997	0.000
M89.33 Hypertrophy of bone (Forearm)	0.002	0.997	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.002	0.997	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.002	0.997	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.002	0.997	0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.003	0.997	0.000
H53.2 Diplopia	0.003	0.997	0.000
J39 Other diseases of upper respiratory tract	0.000	0.997	0.003
M89.59 Osteolysis (Site unspecified)	0.002	0.997	0.000
M89.58 Osteolysis (Other)	0.002	0.997	0.000
M89.57 Osteolysis (Ankle and foot)	0.002	0.997	0.000
M89.56 Osteolysis (Lower leg)	0.002	0.997	0.000
M89.54 Osteolysis (Hand)	0.002	0.997	0.000
M89.53 Osteolysis (Forearm)	0.002	0.997	0.000
M89.52 Osteolysis (Upper arm)	0.002	0.997	0.000
M89.51 Osteolysis (Shoulder region)	0.002	0.997	0.000
M89.50 Osteolysis (Multiple sites)	0.002	0.997	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.997	0.003
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.997	0.003
M89.98 Disorder of bone, unspecified (Other)	0.002	0.997	0.000
I27.0 Primary pulmonary hypertension	0.003	0.997	0.000
I42.0 Dilated cardiomyopathy	0.003	0.997	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.002	0.997	0.000
M89.18 Epiphyseal arrest (Other)	0.002	0.997	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.002	0.997	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.002	0.997	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.002	0.997	0.000
M89.14 Epiphyseal arrest (Hand)	0.002	0.997	0.000
M89.13 Epiphyseal arrest (Forearm)	0.002	0.997	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.002	0.997	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.002	0.997	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.002	0.997	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.002	0.997	0.000
M89.28 Other disorders of bone development and growth (Other)	0.002	0.997	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.002	0.997	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.002	0.997	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.002	0.997	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.002	0.997	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.002	0.997	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.002	0.997	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.002	0.997	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.002	0.997	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.002	0.997	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.002	0.997	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.002	0.997	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.002	0.997	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.002	0.997	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.002	0.997	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.002	0.997	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.002	0.997	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.002	0.997	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.002	0.997	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.002	0.997	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.002	0.997	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.002	0.997	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.002	0.997	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.002	0.997	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.002	0.997	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.002	0.997	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.002	0.997	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.002	0.997	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.002	0.997	0.000
H83.9 Disease of inner ear, unspecified	0.000	0.997	0.002
H83.8 Other specified diseases of inner ear	0.000	0.997	0.002
H83.3 Noise effects on inner ear	0.000	0.997	0.002
H83.2 Labyrinthine dysfunction	0.000	0.997	0.002
H83.1 Labyrinthine fistula	0.000	0.997	0.002
M19.00 Primary arthrosis of other joints (Multiple sites)	0.000	0.997	0.002
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.998	0.002
H13 Disorders of conjunctiva in diseases classified elsewhere	0.000	0.998	0.002
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.998	0.002
H10 Conjunctivitis	0.000	0.998	0.002
C02.9 Tongue, unspecified	0.002	0.998	0.000
C02.1 Border of tongue	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
D86.8 Sarcoidosis of other and combined sites	0.002	0.998	0.000
J39.9 Disease of upper respiratory tract, unspecified	0.000	0.998	0.002
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.000	0.998	0.002
J39.1 Other abscess of pharynx	0.000	0.998	0.002
J39.0 Retropharyngeal and parapharyngeal abscess	0.000	0.998	0.002
Z11.0 Special screening examination for intestinal infectious diseases	0.000	0.998	0.002
K31.9 Disease of stomach and duodenum, unspecified	0.002	0.998	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.998	0.002
J46 Status asthmaticus	0.002	0.998	0.000
I42.9 Cardiomyopathy, unspecified	0.002	0.998	0.000
H10.9 Conjunctivitis, unspecified	0.000	0.998	0.002
N73.6 Female pelvic peritoneal adhesions	0.002	0.998	0.000
M54.59 Low back pain (Site unspecified)	0.002	0.998	0.000
D61.9 Aplastic anaemia, unspecified	0.002	0.998	0.000
I30.9 Acute pericarditis, unspecified	0.000	0.998	0.002
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
N73.9 Female pelvic inflammatory disease, unspecified	0.002	0.998	0.000
C61 Malignant neoplasm of prostate	0.000	0.998	0.002
D25.9 Leiomyoma of uterus, unspecified	0.002	0.998	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.002	0.998	0.000
E10.2 With renal complications	0.000	0.998	0.002
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.000	0.998	0.002
H13.3 Ocular pemphigoid	0.000	0.998	0.002
H13.2 Conjunctivitis in other diseases classified elsewhere	0.000	0.998	0.002
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
H13.0 Filarial infection of conjunctiva	0.000	0.998	0.002
H10.8 Other conjunctivitis	0.000	0.998	0.002
H10.5 Blepharoconjunctivitis	0.000	0.998	0.002
H10.3 Acute conjunctivitis, unspecified	0.000	0.998	0.002
H10.2 Other acute conjunctivitis	0.000	0.998	0.002
H10.1 Acute atopic conjunctivitis	0.000	0.998	0.002
H10.0 Mucopurulent conjunctivitis	0.000	0.998	0.002
J17.3 Pneumonia in parasitic diseases	0.002	0.998	0.000
N73.5 Female pelvic peritonitis, unspecified	0.002	0.998	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.002	0.998	0.000
D84 Other immunodeficiencies	0.002	0.998	0.000
N41.0 Acute prostatitis	0.002	0.998	0.000
I42 Cardiomyopathy	0.002	0.998	0.000
I05.0 Mitral stenosis	0.000	0.998	0.002
E10.9 Without complications	0.000	0.998	0.002
I77.8 Other specified disorders of arteries and arterioles	0.000	0.998	0.002
E10.5 With peripheral circulatory complications	0.000	0.998	0.002
G41.0 Grand mal status epilepticus	0.002	0.998	0.000
T78.3 Angioneurotic oedema	0.000	0.998	0.002
N73 Other female pelvic inflammatory diseases	0.002	0.998	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.000	0.998	0.002
J17.2 Pneumonia in mycoses	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
I42.2 Other hypertrophic cardiomyopathy	0.002	0.998	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.002	0.998	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
J00 Acute nasopharyngitis [common cold]	0.000	0.998	0.002
I84.2 Internal haemorrhoids without complication	0.002	0.998	0.000
J39.8 Other specified diseases of upper respiratory tract	0.000	0.998	0.002
K26.4 Chronic or unspecified with haemorrhage	0.002	0.998	0.000
T93.0 Sequelae of open wound of lower limb	0.002	0.998	0.000
D86 Sarcoidosis	0.002	0.998	0.000
C02.8 Overlapping lesion of tongue	0.001	0.998	0.000
C02.4 Lingual tonsil	0.001	0.998	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.001	0.998	0.000
C02.2 Ventral surface of tongue	0.001	0.998	0.000
C02.0 Dorsal surface of tongue	0.001	0.998	0.000
D84.8 Other specified immunodeficiencies	0.001	0.998	0.000
D84.1 Defects in the complement system	0.001	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.001	0.998	0.000
H02.8 Other specified disorders of eyelid	0.002	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
O16 Unspecified maternal hypertension	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
E10.1 With ketoacidosis	0.000	0.998	0.002
H10.4 Chronic conjunctivitis	0.000	0.998	0.001
I42.7 Cardiomyopathy due to drugs and other external agents	0.001	0.998	0.000
I42.5 Other restrictive cardiomyopathy	0.001	0.998	0.000
I42.4 Endocardial fibroelastosis	0.001	0.998	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.001	0.998	0.000
L81 Other disorders of pigmentation	0.000	0.998	0.002
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.001	0.998	0.000
I42.8 Other cardiomyopathies	0.001	0.998	0.000
M84.03 Malunion of fracture (Forearm)	0.002	0.998	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.998	0.001
I42.6 Alcoholic cardiomyopathy	0.001	0.998	0.000
L29.0 Pruritus ani	0.000	0.998	0.002
N73.8 Other specified female pelvic inflammatory diseases	0.001	0.998	0.000
N73.4 Female chronic pelvic peritonitis	0.001	0.998	0.000
N73.3 Female acute pelvic peritonitis	0.001	0.998	0.000
N73.2 Unspecified parametritis and pelvic cellulitis	0.001	0.998	0.000
N73.1 Chronic parametritis and pelvic cellulitis	0.001	0.998	0.000
U81.0 Vancomycin resistant agent	0.001	0.998	0.000
I05 Rheumatic mitral valve diseases	0.000	0.998	0.002
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.001	0.998	0.000
D89.3 Immune reconstitution syndrome	0.001	0.998	0.000
D89.1 Cryoglobulinaemia	0.001	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.001	0.998	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
A87.9 Viral meningitis, unspecified	0.001	0.998	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.001	0.998	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.001	0.998	0.000
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.000	0.998	0.001
Z30.1 Insertion of (intra-uterine) contraceptive device	0.002	0.998	0.000
O15 Eclampsia	0.001	0.999	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.001	0.999	0.000
G41.9 Status epilepticus, unspecified	0.001	0.999	0.000
S92.0 Fracture of calcaneus	0.001	0.999	0.000
T88.4 Failed or difficult intubation	0.001	0.999	0.000
D80 Immunodeficiency with predominantly antibody defects	0.001	0.999	0.000
B00.5 Herpesviral ocular disease	0.001	0.999	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.001	0.999	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.001	0.999	0.000
N73.0 Acute parametritis and pelvic cellulitis	0.001	0.999	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.001	0.999	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.999	0.001
C62.9 Testis, unspecified	0.000	0.999	0.001
Z11.5 Special screening examination for other viral diseases	0.000	0.999	0.001
L81.9 Disorder of pigmentation, unspecified	0.000	0.999	0.001
T88 Other complications of surgical and medical care, not elsewhere classified	0.001	0.999	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.999	0.001
G71.0 Muscular dystrophy	0.001	0.999	0.000
L81.7 Pigmented purpuric dermatosis	0.000	0.999	0.001
L81.6 Other disorders of diminished melanin formation	0.000	0.999	0.001
L81.5 Leukoderma, not elsewhere classified	0.000	0.999	0.001
L81.3 Cafe au lait spots	0.000	0.999	0.001
L81.1 Chloasma	0.000	0.999	0.001
L81.0 Postinflammatory hyperpigmentation	0.000	0.999	0.001
D83 Common variable immunodeficiency	0.001	0.999	0.000
D82 Immunodeficiency associated with other major defects	0.001	0.999	0.000
D81 Combined immunodeficiencies	0.001	0.999	0.000
I05.8 Other mitral valve diseases	0.000	0.999	0.001
L81.8 Other specified disorders of pigmentation	0.000	0.999	0.001
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
S92.51 Fracture of other toe (open)	0.001	0.999	0.000
I35.0 Aortic (valve) stenosis	0.000	0.999	0.001
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
S92.5 Fracture of other toe	0.001	0.999	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.001	0.999	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
L81.2 Freckles	0.000	0.999	0.001
O15.9 Eclampsia, unspecified as to time period	0.001	0.999	0.000
O15.2 Eclampsia in the puerperium	0.001	0.999	0.000
O15.1 Eclampsia in labour	0.001	0.999	0.000
O15.0 Eclampsia in pregnancy	0.001	0.999	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.001	0.999	0.000
J17 Pneumonia in diseases classified elsewhere	0.001	0.999	0.000
Chapter IX Diseases of the circulatory system	0.000	0.999	0.001
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.001	0.999	0.000
S92.01 Fracture of calcaneus (open)	0.001	0.999	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.001	0.999	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.001	0.999	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.001	0.999	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.001	0.999	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.001	0.999	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.001	0.999	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.001	0.999	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.001	0.999	0.000
E10.7 With multiple complications	0.000	0.999	0.001
J17.1 Pneumonia in viral diseases classified elsewhere	0.001	0.999	0.000
D37.4 Colon	0.001	0.999	0.000
E11.9 Without complications	0.000	0.999	0.001
N95.2 Postmenopausal atrophic vaginitis	0.000	0.999	0.001
C62 Malignant neoplasm of testis	0.000	0.999	0.001
A40.9 Streptococcal septicaemia, unspecified	0.001	0.999	0.000
D14.0 Middle ear, nasal cavity and accessory sinuses	0.001	0.999	0.000
D86.1 Sarcoidosis of lymph nodes	0.001	0.999	0.000
I05.2 Mitral stenosis with insufficiency	0.000	0.999	0.001
T88.9 Complication of surgical and medical care, unspecified	0.001	0.999	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.001	0.999	0.000
T88.2 Shock due to anaesthesia	0.001	0.999	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.001	0.999	0.000
T88.0 Infection following immunisation	0.001	0.999	0.000
D81.9 Combined immunodeficiency, unspecified	0.001	0.999	0.000
D81.8 Other combined immunodeficiencies	0.001	0.999	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.999	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.999	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.999	0.000
D81.4 Nezelof's syndrome	0.001	0.999	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.999	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.999	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.001	0.999	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.001	0.999	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.001	0.999	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.001	0.999	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.001	0.999	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.001	0.999	0.000
D82.2 Immunodeficiency with short-limbed stature	0.001	0.999	0.000
D82.1 Di George's syndrome	0.001	0.999	0.000
D82.0 Wiskott-Aldrich syndrome	0.001	0.999	0.000
D83.9 Common variable immunodeficiency, unspecified	0.001	0.999	0.000
D83.8 Other common variable immunodeficiencies	0.001	0.999	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.001	0.999	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.001	0.999	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.001	0.999	0.000
G00.9 Bacterial meningitis, unspecified	0.001	0.999	0.000
N05.9 Unspecified	0.000	0.999	0.001
S80.9 Superficial injury of lower leg, unspecified	0.001	0.999	0.000
D37.7 Other digestive organs	0.000	0.999	0.001
D80.1 Nonfamilial hypogammaglobulinaemia	0.001	0.999	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.999	0.001
L50.9 Urticaria, unspecified	0.001	0.999	0.000
O87.2 Haemorrhoids in the puerperium	0.001	0.999	0.000
I05-I09 Chronic rheumatic heart diseases	0.000	0.999	0.001
E10.0 With coma	0.000	0.999	0.001
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.001	0.999	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.001	0.999	0.000
T65 Toxic effect of other and unspecified substances	0.001	0.999	0.000
T62 Toxic effect of other noxious substances eaten as food	0.001	0.999	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.001	0.999	0.000
T60 Toxic effect of pesticides	0.001	0.999	0.000
T57 Toxic effect of other inorganic substances	0.001	0.999	0.000
T54 Toxic effect of corrosive substances	0.001	0.999	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.001	0.999	0.000
T52 Toxic effect of organic solvents	0.001	0.999	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.001	0.999	0.000
T55 Toxic effect of soaps and detergents	0.001	0.999	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.000	0.999	0.001
I00-I02 Acute rheumatic fever	0.000	0.999	0.001
G06.2 Extradural and subdural abscess, unspecified	0.001	0.999	0.000
J17.8 Pneumonia in other diseases classified elsewhere	0.001	0.999	0.000
N02.9 Unspecified	0.001	0.999	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.001	0.999	0.000
C62.1 Descended testis	0.000	0.999	0.001
C62.0 Undescended testis	0.000	0.999	0.001
I05.1 Rheumatic mitral insufficiency	0.000	0.999	0.001
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.999	0.001
L53.9 Erythematous condition, unspecified	0.000	0.999	0.001
L91.0 Keloid scar	0.000	0.999	0.001
T59.9 Gases, fumes and vapours, unspecified	0.001	0.999	0.000
Z29.2 Other prophylactic chemotherapy	0.001	0.999	0.000
K26.7 Chronic without haemorrhage or perforation	0.000	0.999	0.001
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.001	0.999	0.000
G41 Status epilepticus	0.001	0.999	0.000
T59 Toxic effect of other gases, fumes and vapours	0.001	0.999	0.000
C60-C63 Malignant neoplasms of male genital organs	0.000	0.999	0.001
E10.8 With unspecified complications	0.000	0.999	0.001
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.001	0.999	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.999	0.001
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.999	0.001
I77.6 Arteritis, unspecified	0.000	0.999	0.001
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.999	0.001
O12.2 Gestational oedema with proteinuria	0.001	0.999	0.000
T52.9 Organic solvent, unspecified	0.001	0.999	0.000
T52.8 Other organic solvents	0.001	0.999	0.000
T52.4 Ketones	0.001	0.999	0.000
T52.3 Glycols	0.001	0.999	0.000
T52.2 Homologues of benzene	0.001	0.999	0.000
T52.1 Benzene	0.001	0.999	0.000
T52.0 Petroleum products	0.001	0.999	0.000
T53.9 Halogen derivative of aliphatic and aromatic hydrocarbons, unspecified	0.001	0.999	0.000
T53.7 Other halogen derivatives of aromatic hydrocarbons	0.001	0.999	0.000
T53.6 Other halogen derivatives of aliphatic hydrocarbons	0.001	0.999	0.000
T53.5 Chlorofluorocarbons	0.001	0.999	0.000
T53.4 Dichloromethane	0.001	0.999	0.000
T53.3 Tetrachloroethylene	0.001	0.999	0.000
T53.2 Trichloroethylene	0.001	0.999	0.000
T53.1 Chloroform	0.001	0.999	0.000
T53.0 Carbon tetrachloride	0.001	0.999	0.000
T54.9 Corrosive substance, unspecified	0.001	0.999	0.000
T54.3 Corrosive alkalis and alklali-like substances	0.001	0.999	0.000
T54.2 Corrosive acids and acid-like substances	0.001	0.999	0.000
T54.1 Other corrosive organic compounds	0.001	0.999	0.000
T54.0 Phenol and phenol homologues	0.001	0.999	0.000
T57.9 Inorganic substance, unspecified	0.001	0.999	0.000
T57.8 Other specified inorganic substances	0.001	0.999	0.000
T57.3 Hydrogen cyanide	0.001	0.999	0.000
T57.2 Manganese and its compounds	0.001	0.999	0.000
T57.1 Phosphorus and its compounds	0.001	0.999	0.000
T57.0 Arsenic and its compounds	0.001	0.999	0.000
T60.9 Pesticide, unspecified	0.001	0.999	0.000
T60.8 Other pesticides	0.001	0.999	0.000
T60.4 Rodenticides	0.001	0.999	0.000
T60.3 Herbicides and fungicides	0.001	0.999	0.000
T60.2 Other insecticides	0.001	0.999	0.000
T60.1 Halogenated insecticides	0.001	0.999	0.000
T60.0 Organophosphate and carbamate insecticides	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations