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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12500459
log Bayes Factor = 8.9164
Chromosome 4   position 3,284,340  (GRCh37) Explore rs12500459 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E66 Obesity
1.000 0.000 0.000
E65-E68 Obesity and other hyperalimentation
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
# Top node
0.999 0.001 0.000
E66.9 Obesity, unspecified
0.999 0.001 0.000
E11.9 Without complications
0.998 0.002 0.000
E66.8 Other obesity
0.997 0.003 0.000
N18 Chronic renal failure
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.996 0.004 0.000
N18.9 Chronic renal failure, unspecified
0.996 0.004 0.000
Chapter VI Diseases of the nervous system
0.994 0.006 0.000
N17-N19 Renal failure
0.994 0.006 0.000
Chapter XIV Diseases of the genitourinary system
0.994 0.006 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.994 0.006 0.000
I25 Chronic ischaemic heart disease
0.992 0.008 0.000
M86-M90 Other osteopathies
0.988 0.012 0.000
Chapter XX External causes of morbidity and mortality
0.985 0.015 0.000
N18.3 Chronic kidney disease, stage 3
0.984 0.016 0.000
I25.1 Atherosclerotic heart disease
0.977 0.023 0.000
N00-N08 Glomerular diseases
0.975 0.025 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.973 0.027 0.000
M05-M14 Inflammatory polyarthropathies
0.973 0.027 0.000
I25.2 Old myocardial infarction
0.973 0.027 0.000
M89 Other disorders of bone
0.964 0.036 0.000
E20-E35 Disorders of other endocrine glands
0.964 0.036 0.000
Y95 Nosocomial condition
0.956 0.044 0.000
E11.2 With renal complications
0.956 0.044 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.954 0.046 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.950 0.050 0.000
M89.8 Other specified disorders of bone
0.945 0.055 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.940 0.060 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.934 0.066 0.000
Chapter V Mental and behavioural disorders
0.932 0.068 0.000
M13 Other arthritis
0.930 0.070 0.000
G70-G73 Diseases of myoneural junction and muscle
0.928 0.072 0.000
Chapter XXII Codes for special purposes
0.928 0.072 0.000
E27 Other disorders of adrenal gland
0.928 0.072 0.000
W20-W49 Exposure to inanimate mechanical forces
0.923 0.077 0.000
M86 Osteomyelitis
0.922 0.078 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.914 0.086 0.000
G82 Paraplegia and tetraplegia
0.912 0.088 0.000
M13.9 Arthritis, unspecified
0.903 0.097 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.898 0.102 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.895 0.105 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.893 0.107 0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)
0.889 0.111 0.000
E27.1 Primary adrenocortical insufficiency
0.877 0.123 0.000
M45-M49 Spondylopathies
0.875 0.125 0.000
N99-N99 Other disorders of the genitourinary system
0.874 0.126 0.000
N18.4 Chronic kidney disease, stage 4
0.873 0.127 0.000
E11.6 With other specified complications
0.871 0.129 0.000
I20-I25 Ischaemic heart diseases
0.871 0.129 0.000
M86.9 Osteomyelitis, unspecified
0.870 0.130 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.868 0.132 0.000
M80-M85 Disorders of bone density and structure
0.866 0.134 0.000
N10-N16 Renal tubulo-interstitial diseases
0.865 0.135 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.858 0.142 0.000
F30-F39 Mood [affective] disorders
0.857 0.143 0.000
Chapter IX Diseases of the circulatory system
0.857 0.143 0.000
I25.5 Ischaemic cardiomyopathy
0.853 0.147 0.000
E11.0 With coma
0.850 0.150 0.000
E14 Unspecified diabetes mellitus
0.847 0.153 0.000
E11.8 With unspecified complications
0.847 0.153 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.846 0.154 0.000
G71 Primary disorders of muscles
0.844 0.156 0.000
N18.8 Other chronic renal failure
0.843 0.157 0.000
W29 Contact with other powered hand tools and household machinery
0.842 0.158 0.000
Z88.0 Personal history of allergy to penicillin
0.842 0.158 0.000
G82.2 Paraplegia, unspecified
0.841 0.159 0.000
G00 Bacterial meningitis, not elsewhere classified
0.840 0.160 0.000
M06 Other rheumatoid arthritis
0.840 0.160 0.000
M07 Psoriatic and enteropathic arthropathies
0.839 0.161 0.000
N03 Chronic nephritic syndrome
0.838 0.162 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.837 0.163 0.000
F60-F69 Disorders of adult personality and behaviour
0.836 0.164 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.832 0.168 0.000
F31 Bipolar affective disorder
0.832 0.168 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.832 0.168 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.831 0.169 0.000
G81 Hemiplegia
0.831 0.169 0.000
G82.5 Tetraplegia, unspecified
0.829 0.171 0.000
E22 Hyperfunction of pituitary gland
0.829 0.171 0.000
F25 Schizoaffective disorders
0.828 0.172 0.000
E24 Cushing's syndrome
0.817 0.183 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.816 0.184 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.813 0.187 0.000
M87 Osteonecrosis
0.811 0.189 0.000
M89.86 Other specified disorders of bone (Lower leg)
0.806 0.194 0.000
U88 Agent resistant to multiple antibiotics
0.803 0.197 0.000
V20-V29 Motorcycle rider injured in transport accident
0.803 0.197 0.000
M13.98 Arthritis, unspecified (Other)
0.798 0.202 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.797 0.203 0.000
F20 Schizophrenia
0.796 0.204 0.000
M06.0 Seronegative rheumatoid arthritis
0.795 0.205 0.000
E29 Testicular dysfunction
0.794 0.206 0.000
M00-M03 Infectious arthropathies
0.790 0.210 0.000
M89.0 Algoneurodystrophy
0.790 0.210 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.789 0.211 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.789 0.211 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.788 0.212 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.788 0.212 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.788 0.212 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.787 0.213 0.000
Y84.0 Cardiac catheterisation
0.786 0.214 0.000
W29.9 Unspecified place
0.784 0.216 0.000
M14 Arthropathies in other diseases classified elsewhere
0.782 0.218 0.000
G58 Other mononeuropathies
0.780 0.220 0.000
F60 Specific personality disorders
0.778 0.222 0.000
M89.3 Hypertrophy of bone
0.777 0.223 0.000
N25-N29 Other disorders of kidney and ureter
0.769 0.231 0.000
M89.87 Other specified disorders of bone (Ankle and foot)
0.768 0.232 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.763 0.237 0.000
E26 Hyperaldosteronism
0.761 0.239 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.758 0.242 0.000
G57 Mononeuropathies of lower limb
0.758 0.242 0.000
G52 Disorders of other cranial nerves
0.757 0.243 0.000
N18.5 Chronic kidney disease, stage 5
0.755 0.245 0.000
E22.0 Acromegaly and pituitary gigantism
0.754 0.246 0.000
V40-V49 Car occupant injured in transport accident
0.753 0.247 0.000
E40-E46 Malnutrition
0.753 0.247 0.000
E14.9 Without complications
0.752 0.248 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.751 0.249 0.000
M80 Osteoporosis with pathological fracture
0.751 0.249 0.000
G30-G32 Other degenerative diseases of the nervous system
0.750 0.249 0.000
G54 Nerve root and plexus disorders
0.750 0.250 0.000
G71.0 Muscular dystrophy
0.748 0.252 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.748 0.252 0.000
M07.3 Other psoriatic arthropathies
0.743 0.257 0.000
V01-V09 Pedestrian injured in transport accident
0.743 0.257 0.000
G72 Other myopathies
0.742 0.257 0.000
F25.1 Schizoaffective disorder, depressive type
0.741 0.259 0.000
N03.9 Unspecified
0.741 0.259 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.740 0.260 0.000
M89.88 Other specified disorders of bone (Other)
0.738 0.261 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.738 0.262 0.000
M81 Osteoporosis without pathological fracture
0.738 0.262 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.737 0.263 0.000
N04 Nephrotic syndrome
0.735 0.265 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.734 0.266 0.000
M45 Ankylosing spondylitis
0.733 0.267 0.000
F20.9 Schizophrenia, unspecified
0.732 0.268 0.000
Y91.9 Alcohol involvement, not otherwise specified
0.732 0.268 0.000
N99.3 Prolapse of vaginal vault after hysterectomy
0.730 0.270 0.000
W00-W19 Falls
0.730 0.270 0.000
M05 Seropositive rheumatoid arthritis
0.727 0.273 0.000
W20 Struck by thrown, projected or falling object
0.726 0.274 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.726 0.274 0.000
M50-M54 Other dorsopathies
0.725 0.275 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.725 0.275 0.000
E11.4 With neurological complications
0.721 0.279 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.720 0.280 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.719 0.280 0.000
G70 Myasthenia gravis and other myoneural disorders
0.718 0.282 0.000
E66.1 Drug-induced obesity
0.717 0.283 0.000
E67 Other hyperalimentation
0.717 0.283 0.000
E68 Sequelae of hyperalimentation
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.716 0.283 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
E65 Localised adiposity
0.715 0.285 0.000
N18.1 Chronic kidney disease, stage 1
0.715 0.285 0.000
G00.1 Pneumococcal meningitis
0.715 0.285 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.715 0.285 0.000
G37 Other demyelinating diseases of central nervous system
0.714 0.286 0.000
E10 Insulin-dependent diabetes mellitus
0.713 0.287 0.000
I25.6 Silent myocardial ischaemia
0.712 0.288 0.000
F29 Unspecified nonorganic psychosis
0.711 0.289 0.000
G81.1 Spastic hemiplegia
0.711 0.289 0.000
E11.5 With peripheral circulatory complications
0.709 0.290 0.000
I25.4 Coronary artery aneurysm
0.708 0.292 0.000
E66.0 Obesity due to excess calories
0.708 0.292 0.000
F60.3 Emotionally unstable personality disorder
0.708 0.292 0.000
M49 Spondylopathies in diseases classified elsewhere
0.707 0.293 0.000
I24 Other acute ischaemic heart diseases
0.707 0.293 0.000
Y35-Y36 Legal intervention and operations of war
0.706 0.294 0.000
Y10-Y34 Event of undetermined intent
0.706 0.294 0.000
X85-X99 Assault
0.706 0.294 0.000
X30-X39 Exposure to forces of nature
0.706 0.294 0.000
X00-X09 Exposure to smoke, fire and flames
0.706 0.294 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.706 0.294 0.000
W65-W74 Accidental drowning and submersion
0.706 0.294 0.000
V95-V97 Air and space transport accidents
0.706 0.294 0.000
V90-V94 Water transport accidents
0.706 0.294 0.000
V70-V79 Bus occupant injured in transport accident
0.706 0.294 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.706 0.294 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.706 0.294 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.706 0.294 0.000
E20 Hypoparathyroidism
0.705 0.294 0.000
M82 Osteoporosis in diseases classified elsewhere
0.705 0.295 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.704 0.295 0.000
G00.9 Bacterial meningitis, unspecified
0.704 0.295 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.704 0.296 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.701 0.299 0.000
E27.9 Disorder of adrenal gland, unspecified
0.699 0.301 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.699 0.301 0.000
N06 Isolated proteinuria with specified morphological lesion
0.699 0.301 0.000
N01 Rapidly progressive nephritic syndrome
0.699 0.301 0.000
N00 Acute nephritic syndrome
0.699 0.301 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.699 0.301 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.698 0.302 0.000
Y98 Lifestyle-related condition
0.698 0.302 0.000
Y97 Environmental-pollution-related condition
0.698 0.302 0.000
Y96 Work-related condition
0.698 0.302 0.000
M12 Other specific arthropathies
0.697 0.302 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.697 0.302 0.000
M08 Juvenile arthritis
0.697 0.302 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.696 0.304 0.000
M89.5 Osteolysis
0.696 0.304 0.000
F31.7 Bipolar affective disorder, currently in remission
0.695 0.305 0.000
M06.3 Rheumatoid nodule
0.694 0.306 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.692 0.308 0.000
M89.81 Other specified disorders of bone (Shoulder region)
0.692 0.308 0.000
M89.6 Osteopathy after poliomyelitis
0.691 0.309 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.691 0.309 0.000
M89.2 Other disorders of bone development and growth
0.691 0.309 0.000
M89.1 Epiphyseal arrest
0.691 0.309 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.691 0.309 0.000
E32 Diseases of thymus
0.691 0.309 0.000
E31 Polyglandular dysfunction
0.691 0.309 0.000
E30 Disorders of puberty, not elsewhere classified
0.691 0.309 0.000
E25 Adrenogenital disorders
0.691 0.309 0.000
W21 Striking against or struck by sports equipment
0.690 0.310 0.000
F99-F99 Unspecified mental disorder
0.690 0.310 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.689 0.311 0.000
W25 Contact with sharp glass
0.688 0.312 0.000
F25.0 Schizoaffective disorder, manic type
0.688 0.312 0.000
M13.0 Polyarthritis, unspecified
0.687 0.312 0.000
M60-M63 Disorders of muscles
0.687 0.313 0.000
M46 Other inflammatory spondylopathies
0.684 0.316 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.684 0.316 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.684 0.316 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.684 0.316 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.684 0.316 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.684 0.316 0.000
Q80-Q89 Other congenital malformations
0.682 0.318 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.681 0.319 0.000
X10-X19 Contact with heat and hot substances
0.679 0.320 0.000
W22 Striking against or struck by other objects
0.678 0.322 0.000
M89.89 Other specified disorders of bone (Site unspecified)
0.677 0.323 0.000
M89.84 Other specified disorders of bone (Hand)
0.677 0.323 0.000
M89.83 Other specified disorders of bone (Forearm)
0.677 0.323 0.000
M89.82 Other specified disorders of bone (Upper arm)
0.677 0.323 0.000
M89.80 Other specified disorders of bone (Multiple sites)
0.677 0.323 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.677 0.323 0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.677 0.323 0.000
E27.8 Other specified disorders of adrenal gland
0.676 0.324 0.000
M86.6 Other chronic osteomyelitis
0.676 0.324 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.674 0.326 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.674 0.326 0.000
M86.8 Other osteomyelitis
0.673 0.326 0.000
X20-X29 Contact with venomous animals and plants
0.673 0.326 0.000
E29.1 Testicular hypofunction
0.672 0.328 0.000
X50-X57 Overexertion, travel and privation
0.670 0.329 0.000
V98-V99 Other and unspecified transport accidents
0.669 0.331 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.668 0.332 0.000
N26 Unspecified contracted kidney
0.668 0.332 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.668 0.332 0.000
F80-F89 Disorders of psychological development
0.668 0.332 0.000
M95.4 Acquired deformity of chest and rib
0.668 0.332 0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)
0.667 0.333 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.666 0.334 0.000
E27.2 Addisonian crisis
0.666 0.334 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.665 0.334 0.000
E14.2 Withrenal complications
0.665 0.335 0.000
E27.5 Adrenomedullary hyperfunction
0.665 0.335 0.000
E27.0 Other adrenocortical overactivity
0.665 0.335 0.000
E13 Other specified diabetes mellitus
0.665 0.335 0.000
G81.9 Hemiplegia, unspecified
0.665 0.335 0.000
M89.09 Algoneurodystrophy (Site unspecified)
0.664 0.335 0.000
W28 Contact with powered lawn mower
0.664 0.336 0.000
F34 Persistent mood [affective] disorders
0.664 0.336 0.000
M87.9 Osteonecrosis, unspecified
0.662 0.338 0.000
E24.2 Drug-induced Cushing's syndrome
0.662 0.338 0.000
W46 Contact with hypodermic needle
0.662 0.338 0.000
W43 Exposure to vibration
0.662 0.338 0.000
W42 Exposure to noise
0.662 0.338 0.000
W41 Exposure to high-pressure jet
0.662 0.338 0.000
W40 Explosion of other materials
0.662 0.338 0.000
W39 Discharge of firework
0.662 0.338 0.000
W38 Explosion and rupture of other specified pressurised devices
0.662 0.338 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.662 0.338 0.000
W36 Explosion and rupture of gas cylinder
0.662 0.338 0.000
W35 Explosion and rupture of boiler
0.662 0.338 0.000
W34 Discharge from other and unspecified firearms
0.662 0.338 0.000
W33 Rifle, shotgun and larger firearm discharge
0.662 0.338 0.000
W32 Handgun discharge
0.662 0.338 0.000
W31 Contact with other and unspecified machinery
0.662 0.338 0.000
W30 Contact with agricultural machinery
0.662 0.338 0.000
W27 Contact with nonpowered hand tool
0.662 0.338 0.000
W26 Contact with knife, sword or dagger
0.662 0.338 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.662 0.338 0.000
G90-G99 Other disorders of the nervous system
0.662 0.338 0.000
W06 Fall involving bed
0.661 0.339 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.661 0.339 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.661 0.339 0.000
M86.3 Chronic multifocal osteomyelitis
0.661 0.339 0.000
M86.2 Subacute osteomyelitis
0.661 0.339 0.000
M86.1 Other acute osteomyelitis
0.661 0.339 0.000
M86.0 Acute haematogenous osteomyelitis
0.661 0.339 0.000
G82.4 Spastic tetraplegia
0.661 0.339 0.000
M70-M79 Other soft tissue disorders
0.661 0.339 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.658 0.342 0.000
G57.8 Other mononeuropathies of lower limb
0.657 0.343 0.000
G71.1 Myotonic disorders
0.657 0.343 0.000
W45 Foreign body or object entering through skin
0.657 0.343 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.655 0.345 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.655 0.345 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.654 0.346 0.000
G82.3 Flaccid tetraplegia
0.654 0.346 0.000
G82.0 Flaccid paraplegia
0.654 0.346 0.000
M83 Adult osteomalacia
0.653 0.346 0.000
G71.3 Mitochondrial myopathy, not elsewhere classified
0.653 0.347 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.653 0.347 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.652 0.347 0.000
G52.9 Cranial nerve disorder, unspecified
0.652 0.348 0.000
N05 Unspecified nephritic syndrome
0.652 0.348 0.000
V20 Motorcycle rider injured in collision with pedestrian or animal
0.652 0.348 0.000
M54 Dorsalgia
0.650 0.350 0.000
M88 Paget's disease of bone [osteitis deformans]
0.649 0.351 0.000
M14.6 Neuropathic arthropathy
0.646 0.354 0.000
G03 Meningitis due to other and unspecified causes
0.644 0.355 0.000
U80 Agent resistant to penicillin and related antibiotics
0.644 0.356 0.000
N99.2 Postprocedural adhesions of vagina
0.644 0.356 0.000
M13.8 Other specified arthritis
0.643 0.356 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.643 0.357 0.000
M89.38 Hypertrophy of bone (Other)
0.643 0.357 0.000
M99 Biomechanical lesions, not elsewhere classified
0.642 0.358 0.000
M81.4 Drug-induced osteoporosis
0.642 0.358 0.000
F28 Other nonorganic psychotic disorders
0.640 0.360 0.000
F24 Induced delusional disorder
0.640 0.360 0.000
F21 Schizotypal disorder
0.640 0.360 0.000
M48 Other spondylopathies
0.640 0.360 0.000
M86.96 Osteomyelitis, unspecified (Lower leg)
0.639 0.361 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.638 0.362 0.000
M95.1 Cauliflower ear
0.637 0.363 0.000
G30 Alzheimer's disease
0.637 0.363 0.000
U89 Agent resistant to other and unspecified antibiotics
0.636 0.363 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.636 0.364 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.636 0.364 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.636 0.364 0.000
F70-F79 Mental retardation
0.635 0.365 0.000
N02 Recurrent and persistent haematuria
0.634 0.366 0.000
G58.8 Other specified mononeuropathies
0.633 0.367 0.000
Y84.6 Urinary catheterisation
0.632 0.367 0.000
E24.0 Pituitary-dependent Cushing's disease
0.632 0.368 0.000
M13.1 Monoarthritis, not elsewhere classified
0.632 0.368 0.000
D50-D53 Nutritional anaemias
0.631 0.368 0.000
D80-D89 Certain disorders involving the immune mechanism
0.631 0.369 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.630 0.369 0.000
V28 Motorcycle rider injured in noncollision transport accident
0.629 0.371 0.000
M77 Other enthesopathies
0.628 0.372 0.000
G54.6 Phantom limb syndrome with pain
0.627 0.373 0.000
X47 Accidental poisoning by and exposure to other gases and vapours
0.627 0.373 0.000
Y00-Y09 Assault
0.627 0.373 0.000
E10.5 With peripheral circulatory complications
0.626 0.374 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.625 0.375 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.624 0.375 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.624 0.376 0.000
G58.9 Mononeuropathy, unspecified
0.624 0.376 0.000
M86.93 Osteomyelitis, unspecified (Forearm)
0.624 0.376 0.000
M86.92 Osteomyelitis, unspecified (Upper arm)
0.624 0.376 0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)
0.624 0.376 0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)
0.624 0.376 0.000
G50 Disorders of trigeminal nerve
0.622 0.378 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.621 0.379 0.000
M86.98 Osteomyelitis, unspecified (Other)
0.621 0.379 0.000
E28 Ovarian dysfunction
0.621 0.379 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.620 0.380 0.000
E24.9 Cushing's syndrome, unspecified
0.620 0.380 0.000
F60.7 Dependent personality disorder
0.618 0.382 0.000
F25.9 Schizoaffective disorder, unspecified
0.618 0.382 0.000
W50-W64 Exposure to animate mechanical forces
0.616 0.384 0.000
U84 Resistance to other antimicrobial drugs
0.615 0.385 0.000
U83 Resistance to other antibiotics
0.615 0.385 0.000
U82 Resistance to betalactam antibiotics
0.615 0.385 0.000
U85 Resistance to antineoplastic drugs
0.615 0.385 0.000
F33 Recurrent depressive disorder
0.615 0.385 0.000
M00 Pyogenic arthritis
0.615 0.385 0.000
F22 Persistent delusional disorders
0.615 0.385 0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus
0.615 0.385 0.000
E22.1 Hyperprolactinaemia
0.615 0.385 0.000
E26.0 Primary hyperaldosteronism
0.615 0.385 0.000
N27 Small kidney of unknown cause
0.615 0.385 0.000
F39 Unspecified mood [affective] disorder
0.615 0.385 0.000
F38 Other mood [affective] disorders
0.615 0.385 0.000
I00-I02 Acute rheumatic fever
0.614 0.385 0.000
M87.2 Osteonecrosis due to previous trauma
0.614 0.386 0.000
G57.5 Tarsal tunnel syndrome
0.613 0.387 0.000
N99.1 Postprocedural urethral stricture
0.612 0.388 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.610 0.390 0.000
E14.1 With ketoacidosis
0.610 0.390 0.000
X49.9 Unspecified place
0.609 0.391 0.000
G95 Other diseases of spinal cord
0.609 0.391 0.000
E10.2 With renal complications
0.609 0.391 0.000
E14.8 With unspecified complications
0.607 0.393 0.000
E14.7 With multiple complications
0.607 0.393 0.000
E14.6 With other specified complications
0.607 0.393 0.000
E14.5 With peripheral circulatory complications
0.607 0.393 0.000
E14.0 With coma
0.607 0.393 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.607 0.393 0.000
G71.9 Primary disorder of muscle, unspecified
0.605 0.394 0.000
G71.8 Other primary disorders of muscles
0.605 0.394 0.000
G71.2 Congenital myopathies
0.605 0.394 0.000
F20.5 Residual schizophrenia
0.605 0.395 0.000
W29.8 Other specified place
0.604 0.396 0.000
W29.6 Industrial and construction area
0.604 0.396 0.000
W29.0 Home
0.604 0.396 0.000
W29.7 Farm
0.604 0.396 0.000
W29.5 Trade and service area
0.604 0.396 0.000
W29.4 Street and highway
0.604 0.396 0.000
W29.3 Sports and athletics area
0.604 0.396 0.000
W29.2 School, other institution and public administrative area
0.604 0.396 0.000
W29.1 Residential institution
0.604 0.396 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.603 0.397 0.000
M89.07 Algoneurodystrophy (Ankle and foot)
0.603 0.397 0.000
G00.8 Other bacterial meningitis
0.602 0.398 0.000
G00.3 Staphylococcal meningitis
0.602 0.398 0.000
G00.2 Streptococcal meningitis
0.602 0.398 0.000
G00.0 Haemophilus meningitis
0.602 0.398 0.000
M06.8 Other specified rheumatoid arthritis
0.602 0.398 0.000
M06.2 Rheumatoid bursitis
0.602 0.398 0.000
M06.1 Adult-onset Still's disease
0.602 0.398 0.000
M02 Reactive arthropathies
0.602 0.398 0.000
M07.6 Other enteropathic arthropathies
0.602 0.398 0.000
M07.5 Arthropathy in ulcerative colitis
0.602 0.398 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.602 0.398 0.000
M07.2 Psoriatic spondylitis
0.602 0.398 0.000
M07.1 Arthritis mutilans
0.602 0.398 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.602 0.398 0.000
G54.8 Other nerve root and plexus disorders
0.601 0.399 0.000
N03.8 Other
0.601 0.399 0.000
N03.7 Diffuse crescentic glomerulonephritis
0.601 0.399 0.000
N03.6 Dense deposit disease
0.601 0.399 0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.601 0.399 0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis
0.601 0.399 0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis
0.601 0.399 0.000
N03.2 Diffuse membranous glomerulonephritis
0.601 0.399 0.000
N03.1 Focal and segmental glomerular lesions
0.601 0.399 0.000
N03.0 Minor glomerular abnormality
0.601 0.399 0.000
X48 Accidental poisoning by and exposure to pesticides
0.600 0.399 0.000
X46 Accidental poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.600 0.399 0.000
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.600 0.399 0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system
0.600 0.399 0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.600 0.399 0.000
X40 Accidental poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.600 0.399 0.000
F68 Other disorders of adult personality and behaviour
0.599 0.400 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.599 0.400 0.000
F65 Disorders of sexual preference
0.599 0.400 0.000
F63 Habit and impulse disorders
0.599 0.400 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.599 0.400 0.000
F61 Mixed and other personality disorders
0.599 0.400 0.000
N99.5 Malfunction of external stoma of urinary tract
0.599 0.400 0.000
G96 Other disorders of central nervous system
0.599 0.401 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.599 0.401 0.000
F60.9 Personality disorder, unspecified
0.599 0.401 0.000
G36 Other acute disseminated demyelination
0.599 0.401 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.598 0.401 0.000
G83 Other paralytic syndromes
0.597 0.402 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.597 0.403 0.000
Y91.3 Very severe alcohol intoxication
0.597 0.403 0.000
Y91.2 Severe alcohol intoxication
0.597 0.403 0.000
Y91.1 Moderate alcohol intoxication
0.597 0.403 0.000
Y91.0 Mild alcohol intoxication
0.597 0.403 0.000
F31.8 Other bipolar affective disorders
0.597 0.403 0.000
G81.0 Flaccid hemiplegia
0.596 0.404 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.596 0.404 0.000
M86.94 Osteomyelitis, unspecified (Hand)
0.595 0.404 0.000
Y81 General- and plastic-surgery devices associated with adverse incidents
0.595 0.405 0.000
F69 Unspecified disorder of adult personality and behaviour
0.595 0.405 0.000
I20 Angina pectoris
0.595 0.405 0.000
V80-V89 Other land transport accidents
0.595 0.405 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.594 0.405 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.594 0.406 0.000
E22.8 Other hyperfunction of pituitary gland
0.594 0.406 0.000
F25.8 Other schizoaffective disorders
0.594 0.406 0.000
F25.2 Schizoaffective disorder, mixed type
0.594 0.406 0.000
N10 Acute tubulo-interstitial nephritis
0.594 0.406 0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.594 0.406 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.593 0.407 0.000
W20.0 Home
0.593 0.407 0.000
G30.0 Alzheimer's disease with early onset
0.593 0.407 0.000
E50-E64 Other nutritional deficiencies
0.590 0.410 0.000
M71 Other bursopathies
0.590 0.410 0.000
G54.4 Lumbosacral root disorders, not elsewhere classified
0.590 0.410 0.000
M82.1 Osteoporosis in endocrine disorders
0.589 0.411 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.586 0.413 0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)
0.586 0.414 0.000
G82.1 Spastic paraplegia
0.586 0.414 0.000
E24.8 Other Cushing's syndrome
0.586 0.414 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.586 0.414 0.000
E24.3 Ectopic ACTH syndrome
0.586 0.414 0.000
E24.1 Nelson's syndrome
0.586 0.414 0.000
F30 Manic episode
0.586 0.414 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.586 0.414 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.585 0.415 0.000
Q00-Q07 Congenital malformations of the nervous system
0.585 0.415 0.000
G72.4 Inflammatory myopathy, not elsewhere classified
0.585 0.415 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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