TreeWAS – Variant ID: rs1250550

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H04.2 Epiphora	0.000	0.562	0.438
H04 Disorders of lachrymal system	0.000	0.582	0.418
H04.5 Stenosis and insufficiency of lachrymal passages	0.000	0.592	0.408
H00.1 Chalazion	0.000	0.628	0.372
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.000	0.628	0.372
H00 Hordeolum and chalazion	0.000	0.629	0.371
H04.8 Other disorders of lachrymal system	0.000	0.677	0.323
H04.3 Acute and unspecified inflammation of lachrymal passages	0.000	0.678	0.322
H04.0 Dacryoadenitis	0.000	0.700	0.300
H04.9 Disorder of lachrymal system, unspecified	0.000	0.715	0.285
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.726	0.274
H01 Other inflammation of eyelid	0.000	0.732	0.268
H03 Disorders of eyelid in diseases classified elsewhere	0.000	0.733	0.267
H02.1 Ectropion of eyelid	0.000	0.743	0.257
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.000	0.745	0.255
H04.6 Other changes in lachrymal passages	0.000	0.745	0.255
H02 Other disorders of eyelid	0.000	0.748	0.252
H02.5 Other disorders affecting eyelid function	0.000	0.776	0.224
H01.8 Other specified inflammation of eyelid	0.000	0.776	0.224
E03.9 Hypothyroidism, unspecified	0.213	0.787	0.000
H04.4 Chronic inflammation of lachrymal passages	0.000	0.798	0.201
H04.1 Other disorders of lachrymal gland	0.000	0.800	0.200
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.000	0.808	0.192
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.000	0.808	0.191
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.000	0.808	0.191
H02.2 Lagophthalmos	0.000	0.810	0.190
H01.0 Blepharitis	0.000	0.816	0.184
H06.3 Other disorders of orbit in diseases classified elsewhere	0.000	0.817	0.183
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.000	0.817	0.183
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.000	0.817	0.183
H01.9 Inflammation of eyelid, unspecified	0.000	0.821	0.179
H06.2 Dysthyroid exophthalmos	0.000	0.828	0.172
H01.1 Non-infectious dermatoses of eyelid	0.000	0.828	0.171
H05 Disorders of orbit	0.000	0.831	0.168
H02.7 Other degenerative disorders of eyelid and periocular area	0.000	0.852	0.148
H05.8 Other disorders of orbit	0.000	0.855	0.145
H02.6 Xanthelasma of eyelid	0.000	0.855	0.145
E03 Other hypothyroidism	0.141	0.859	0.000
H02.9 Disorder of eyelid, unspecified	0.000	0.868	0.132
H02.0 Entropion and trichiasis of eyelid	0.000	0.877	0.123
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.000	0.879	0.121
H05.3 Deformity of orbit	0.000	0.879	0.121
H05.1 Chronic inflammatory disorders of orbit	0.000	0.879	0.121
H05.9 Disorder of orbit, unspecified	0.000	0.881	0.119
E03.1 Congenital hypothyroidism without goitre	0.113	0.887	0.000
E03.8 Other specified hypothyroidism	0.104	0.896	0.000
E03.5 Myxoedema coma	0.101	0.899	0.000
E03.4 Atrophy of thyroid (acquired)	0.101	0.899	0.000
E03.3 Postinfectious hypothyroidism	0.101	0.899	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.101	0.899	0.000
H05.4 Enophthalmos	0.000	0.900	0.099
H02.3 Blepharochalasis	0.000	0.903	0.097
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.091	0.909	0.000
C44.3 Skin of other and unspecified parts of face	0.000	0.909	0.091
H05.2 Exophthalmic conditions	0.000	0.911	0.089
E00-E07 Disorders of thyroid gland	0.075	0.925	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.066	0.934	0.000
E05.9 Thyrotoxicosis, unspecified	0.064	0.936	0.000
E04 Other non-toxic goitre	0.060	0.940	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.059	0.941	0.000
L81.4 Other melanin hyperpigmentation	0.000	0.942	0.058
E04.2 Non-toxic multinodular goitre	0.057	0.943	0.000
C44.0 Skin of lip	0.000	0.946	0.054
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.054	0.946	0.000
E00 Congenital iodine-deficiency syndrome	0.054	0.946	0.000
C44 Other malignant neoplasms of skin	0.000	0.947	0.053
H05.0 Acute inflammation of orbit	0.001	0.949	0.050
E04.9 Non-toxic goitre, unspecified	0.048	0.952	0.000
E05.5 Thyroid crisis or storm	0.047	0.952	0.000
E05.4 Thyrotoxicosis factitia	0.047	0.952	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.047	0.952	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.047	0.952	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.000	0.953	0.047
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.045	0.955	0.000
E07 Other disorders of thyroid	0.044	0.956	0.000
E04.8 Other specified non-toxic goitre	0.043	0.957	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.041	0.959	0.000
E05.8 Other thyrotoxicosis	0.040	0.960	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.039	0.961	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.039	0.961	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.039	0.961	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.039	0.961	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.039	0.961	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.039	0.961	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.039	0.961	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.039	0.961	0.000
C44.8 Overlapping lesion of skin	0.000	0.962	0.038
E07.8 Other specified disorders of thyroid	0.036	0.964	0.000
E06 Thyroiditis	0.034	0.966	0.000
C44.2 Skin of ear and external auricular canal	0.000	0.967	0.033
E04.0 Non-toxic diffuse goitre	0.032	0.968	0.000
C44.7 Skin of lower limb, including hip	0.000	0.968	0.032
E07.1 Dyshormogenetic goitre	0.031	0.968	0.000
E07.0 Hypersecretion of calcitonin	0.031	0.968	0.000
C44.6 Skin of upper limb, including shoulder	0.000	0.970	0.030
C44.5 Skin of trunk	0.000	0.972	0.028
E06.1 Subacute thyroiditis	0.025	0.975	0.000
E06.5 Other chronic thyroiditis	0.024	0.975	0.000
E06.4 Drug-induced thyroiditis	0.024	0.975	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.024	0.975	0.000
E06.0 Acute thyroiditis	0.024	0.975	0.000
C44.1 Skin of eyelid, including canthus	0.000	0.976	0.024
E11.9 Without complications	0.023	0.977	0.000
E06.9 Thyroiditis, unspecified	0.020	0.980	0.000
H02.4 Ptosis of eyelid	0.000	0.982	0.018
E04.1 Non-toxic single thyroid nodule	0.018	0.982	0.000
E11 Non-insulin-dependent diabetes mellitus	0.017	0.983	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.983	0.017
E13.9 Without complications	0.017	0.983	0.000
E13 Other specified diabetes mellitus	0.016	0.984	0.000
E10-E14 Diabetes mellitus	0.016	0.984	0.000
E11.0 With coma	0.015	0.985	0.000
K55.2 Angiodysplasia of colon	0.015	0.985	0.000
H02.8 Other specified disorders of eyelid	0.000	0.986	0.014
E11.8 With unspecified complications	0.014	0.986	0.000
E11.2 With renal complications	0.014	0.986	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.014	0.986	0.000
E06.3 Autoimmune thyroiditis	0.013	0.987	0.000
E11.7 With multiple complications	0.012	0.988	0.000
E13.8 With unspecified complications	0.012	0.988	0.000
E13.7 With multiple complications	0.012	0.988	0.000
E13.6 With other specified complications	0.012	0.988	0.000
E13.5 With peripheral circulatory complications	0.012	0.988	0.000
E13.4 With neurological complications	0.012	0.988	0.000
E13.2 With renal complications	0.012	0.988	0.000
E13.1 With ketoacidosis	0.012	0.988	0.000
E13.0 With coma	0.012	0.988	0.000
E13.3 With ophthalmic complications	0.012	0.988	0.000
E12 Malnutrition-related diabetes mellitus	0.011	0.988	0.000
Z50.5 Speech therapy	0.011	0.989	0.000
L81 Other disorders of pigmentation	0.000	0.989	0.011
E11.1 With ketoacidosis	0.011	0.989	0.000
E11.6 With other specified complications	0.010	0.989	0.000
E10 Insulin-dependent diabetes mellitus	0.010	0.990	0.000
Z50.4 Psychotherapy, not elsewhere classified	0.010	0.990	0.000
E40-E46 Malnutrition	0.010	0.990	0.000
C43 Malignant melanoma of skin	0.000	0.990	0.010
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.991	0.009
E11.3 With ophthalmic complications	0.009	0.991	0.000
E10.8 With unspecified complications	0.009	0.991	0.000
L81.2 Freckles	0.000	0.991	0.009
E12.9 Without complications	0.008	0.991	0.000
E12.8 With unspecified complications	0.008	0.991	0.000
E12.7 With multiple complications	0.008	0.991	0.000
E12.6 With other specified complications	0.008	0.991	0.000
E12.5 With peripheral circulatory complications	0.008	0.991	0.000
E12.4 With neurological complications	0.008	0.991	0.000
E12.3 With ophthalmic complications	0.008	0.991	0.000
E12.2 With renal complications	0.008	0.991	0.000
E12.1 With ketoacidosis	0.008	0.991	0.000
E12.0 With coma	0.008	0.991	0.000
C43.4 Malignant melanoma of scalp and neck	0.000	0.992	0.008
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.008	0.992	0.000
E10.2 With renal complications	0.008	0.992	0.000
E10.5 With peripheral circulatory complications	0.008	0.992	0.000
L81.7 Pigmented purpuric dermatosis	0.000	0.992	0.008
L81.6 Other disorders of diminished melanin formation	0.000	0.992	0.008
L81.5 Leukoderma, not elsewhere classified	0.000	0.992	0.008
L81.3 Cafe au lait spots	0.000	0.992	0.008
L81.1 Chloasma	0.000	0.992	0.008
E10.7 With multiple complications	0.008	0.992	0.000
E65-E68 Obesity and other hyperalimentation	0.008	0.992	0.000
E10.4 With neurological complications	0.008	0.992	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.992	0.008
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.008	0.992	0.000
E10.6 With other specified complications	0.008	0.992	0.000
E10.0 With coma	0.007	0.992	0.000
J94.8 Other specified pleural conditions	0.008	0.992	0.000
D41.0 Kidney	0.000	0.993	0.007
E44 Protein-energy malnutrition of moderate and mild degree	0.007	0.993	0.000
E45 Retarded development following protein-energy malnutrition	0.007	0.993	0.000
E43 Unspecified severe protein-energy malnutrition	0.007	0.993	0.000
E42 Marasmic kwashiorkor	0.007	0.993	0.000
E41 Nutritional marasmus	0.007	0.993	0.000
E40 Kwashiorkor	0.007	0.993	0.000
C43.8 Overlapping malignant melanoma of skin	0.000	0.993	0.007
C43.0 Malignant melanoma of lip	0.000	0.993	0.007
C43.5 Malignant melanoma of trunk	0.000	0.993	0.007
E07.9 Disorder of thyroid, unspecified	0.007	0.993	0.000
D37.5 Rectum	0.000	0.993	0.007
C43.9 Malignant melanoma of skin, unspecified	0.000	0.993	0.007
L81.0 Postinflammatory hyperpigmentation	0.000	0.993	0.006
E14 Unspecified diabetes mellitus	0.007	0.993	0.000
E46 Unspecified protein-energy malnutrition	0.007	0.993	0.000
Z50 Care involving use of rehabilitation procedures	0.007	0.993	0.000
E65 Localised adiposity	0.006	0.994	0.000
E15 Nondiabetic hypoglycaemic coma	0.006	0.994	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.994	0.006
E67 Other hyperalimentation	0.006	0.994	0.000
E68 Sequelae of hyperalimentation	0.006	0.994	0.000
L81.9 Disorder of pigmentation, unspecified	0.000	0.994	0.006
L81.8 Other specified disorders of pigmentation	0.000	0.994	0.006
E11.4 With neurological complications	0.006	0.994	0.000
A87.9 Viral meningitis, unspecified	0.006	0.994	0.000
E10.9 Without complications	0.006	0.994	0.000
E14.2 Withrenal complications	0.006	0.994	0.000
E44.1 Mild protein-energy malnutrition	0.005	0.995	0.000
E44.0 Moderate protein-energy malnutrition	0.005	0.995	0.000
E14.8 With unspecified complications	0.005	0.995	0.000
R47.1 Dysarthria and anarthria	0.005	0.995	0.000
T18 Foreign body in alimentary tract	0.005	0.995	0.000
T18.5 Foreign body in anus and rectum	0.005	0.995	0.000
E14.6 With other specified complications	0.005	0.995	0.000
Z50.3 Drug rehabilitation	0.005	0.995	0.000
E14.4 With neurological complications	0.005	0.995	0.000
E14.7 With multiple complications	0.005	0.995	0.000
E14.0 With coma	0.005	0.995	0.000
I44.0 Atrioventricular block, first degree	0.005	0.995	0.000
T18.1 Foreign body in oesophagus	0.005	0.995	0.000
Z50.6 Orthoptic training	0.005	0.995	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.005	0.995	0.000
E50-E64 Other nutritional deficiencies	0.005	0.995	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.000	0.995	0.005
R47.8 Other and unspecified speech disturbances	0.005	0.995	0.000
Z50.2 Alcohol rehabilitation	0.005	0.995	0.000
J94 Other pleural conditions	0.005	0.995	0.000
E20-E35 Disorders of other endocrine glands	0.005	0.995	0.000
S82.21 Fracture of shaft of tibia (open)	0.005	0.995	0.000
E26 Hyperaldosteronism	0.005	0.995	0.000
E14.3 With ophthalmic complications	0.005	0.995	0.000
E10.3 With ophthalmic complications	0.005	0.995	0.000
E67.8 Other specified hyperalimentation	0.004	0.995	0.000
E67.3 Hypervitaminosis D	0.004	0.995	0.000
E67.2 Megavitamin-B6 syndrome	0.004	0.995	0.000
E67.1 Hypercarotenaemia	0.004	0.995	0.000
E67.0 Hypervitaminosis A	0.004	0.995	0.000
E14.5 With peripheral circulatory complications	0.004	0.995	0.000
E26.0 Primary hyperaldosteronism	0.004	0.995	0.000
E16 Other disorders of pancreatic internal secretion	0.004	0.995	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.004	0.996	0.000
J94.2 Haemothorax	0.004	0.996	0.000
E11.5 With peripheral circulatory complications	0.004	0.996	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.996	0.004
E14.1 With ketoacidosis	0.004	0.996	0.000
C44.4 Skin of scalp and neck	0.000	0.996	0.004
T18.3 Foreign body in small intestine	0.004	0.996	0.000
E58 Dietary calcium deficiency	0.004	0.996	0.000
T18.8 Foreign body in other and multiple parts of alimentary tract	0.004	0.996	0.000
T18.4 Foreign body in colon	0.004	0.996	0.000
T18.2 Foreign body in stomach	0.004	0.996	0.000
N04.9 Unspecified	0.004	0.996	0.000
E31 Polyglandular dysfunction	0.004	0.996	0.000
E20 Hypoparathyroidism	0.004	0.996	0.000
E26.9 Hyperaldosteronism, unspecified	0.004	0.996	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.004	0.996	0.000
E63 Other nutritional deficiencies	0.004	0.996	0.000
E56 Other vitamin deficiencies	0.004	0.996	0.000
E50 Vitamin A deficiency	0.004	0.996	0.000
E60 Dietary zinc deficiency	0.004	0.996	0.000
E59 Dietary selenium deficiency	0.004	0.996	0.000
E54 Ascorbic acid deficiency	0.004	0.996	0.000
E52 Niacin deficiency [pellagra]	0.004	0.996	0.000
G70.0 Myasthenia gravis	0.004	0.996	0.000
E51 Thiamine deficiency	0.004	0.996	0.000
T18.0 Foreign body in mouth	0.004	0.996	0.000
T16 Foreign body in ear	0.004	0.996	0.000
R47 Speech disturbances, not elsewhere classified	0.004	0.996	0.000
E24 Cushing's syndrome	0.004	0.996	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.004	0.996	0.000
J94.9 Pleural condition, unspecified	0.004	0.996	0.000
J94.0 Chylous effusion	0.004	0.996	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.004	0.996	0.000
E32 Diseases of thymus	0.004	0.996	0.000
E30 Disorders of puberty, not elsewhere classified	0.004	0.996	0.000
E26.8 Other hyperaldosteronism	0.003	0.996	0.000
E26.1 Secondary hyperaldosteronism	0.003	0.996	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.003	0.996	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.003	0.996	0.000
E16.4 Abnormal secretion of gastrin	0.003	0.996	0.000
E16.3 Increased secretion of glucagon	0.003	0.996	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.003	0.997	0.000
I44.6 Other and unspecified fascicular block	0.003	0.997	0.000
E25 Adrenogenital disorders	0.003	0.997	0.000
E34 Other endocrine disorders	0.003	0.997	0.000
K05.3 Chronic periodontitis	0.003	0.997	0.000
I77.8 Other specified disorders of arteries and arterioles	0.000	0.997	0.003
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.997	0.003
E31.0 Autoimmune polyglandular failure	0.003	0.997	0.000
T15 Foreign body on external eye	0.003	0.997	0.000
E20.9 Hypoparathyroidism, unspecified	0.003	0.997	0.000
J94.1 Fibrothorax	0.003	0.997	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.003	0.997	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.997	0.003
G70.9 Myoneural disorder, unspecified	0.003	0.997	0.000
C71.9 Brain, unspecified	0.000	0.997	0.003
H57.1 Ocular pain	0.003	0.997	0.000
G70 Myasthenia gravis and other myoneural disorders	0.003	0.997	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.000	0.997	0.003
E16.1 Other hypoglycaemia	0.003	0.997	0.000
H57 Other disorders of eye and adnexa	0.003	0.997	0.000
M23.5 Chronic instability of knee	0.000	0.997	0.003
E29 Testicular dysfunction	0.003	0.997	0.000
E20.8 Other hypoparathyroidism	0.003	0.997	0.000
E20.1 Pseudohypoparathyroidism	0.003	0.997	0.000
E20.0 Idiopathic hypoparathyroidism	0.003	0.997	0.000
E31.9 Polyglandular dysfunction, unspecified	0.003	0.997	0.000
E31.8 Other polyglandular dysfunction	0.003	0.997	0.000
E31.1 Polyglandular hyperfunction	0.003	0.997	0.000
I78.1 Naevus, nonneoplastic	0.000	0.997	0.003
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.003	0.997	0.000
H57.8 Other specified disorders of eye and adnexa	0.003	0.997	0.000
E50.9 Vitamin A deficiency, unspecified	0.003	0.997	0.000
E50.8 Other manifestations of vitamin A deficiency	0.003	0.997	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.003	0.997	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.003	0.997	0.000
E50.5 Vitamin A deficiency with night blindness	0.003	0.997	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.003	0.997	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.003	0.997	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.003	0.997	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.003	0.997	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.003	0.997	0.000
E56.9 Vitamin deficiency, unspecified	0.003	0.997	0.000
E56.8 Deficiency of other vitamins	0.003	0.997	0.000
E56.1 Deficiency of vitamin K	0.003	0.997	0.000
E56.0 Deficiency of vitamin E	0.003	0.997	0.000
E63.9 Nutritional deficiency, unspecified	0.003	0.997	0.000
E63.8 Other specified nutritional deficiencies	0.003	0.997	0.000
E63.1 Imbalance of constituents of food intake	0.003	0.997	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.003	0.997	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.003	0.997	0.000
E64.8 Sequelae of other nutritional deficiencies	0.003	0.997	0.000
E64.3 Sequelae of rickets	0.003	0.997	0.000
E64.2 Sequelae of vitamin C deficiency	0.003	0.997	0.000
E64.1 Sequelae of vitamin A deficiency	0.003	0.997	0.000
E64.0 Sequelae of protein-energy malnutrition	0.003	0.997	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.003	0.997	0.000
E51.9 Thiamine deficiency, unspecified	0.003	0.997	0.000
E51.8 Other manifestations of thiamine deficiency	0.003	0.997	0.000
E51.1 Beriberi	0.003	0.997	0.000
E51.2 Wernicke's encephalopathy	0.003	0.997	0.000
D36.7 Other specified sites	0.000	0.997	0.003
I44.2 Atrioventricular block, complete	0.003	0.997	0.000
E24.2 Drug-induced Cushing's syndrome	0.003	0.997	0.000
A87 Viral meningitis	0.003	0.997	0.000
K86.1 Other chronic pancreatitis	0.000	0.997	0.003
E24.8 Other Cushing's syndrome	0.003	0.997	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.003	0.997	0.000
E24.3 Ectopic ACTH syndrome	0.003	0.997	0.000
E24.1 Nelson's syndrome	0.003	0.997	0.000
E24.0 Pituitary-dependent Cushing's disease	0.003	0.997	0.000
E34.3 Short stature, not elsewhere classified	0.003	0.997	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.003	0.997	0.000
E30.9 Disorder of puberty, unspecified	0.003	0.997	0.000
E30.8 Other disorders of puberty	0.003	0.997	0.000
E30.1 Precocious puberty	0.003	0.997	0.000
E30.0 Delayed puberty	0.003	0.997	0.000
E32.9 Disease of thymus, unspecified	0.003	0.997	0.000
E32.8 Other diseases of thymus	0.003	0.997	0.000
E32.1 Abscess of thymus	0.003	0.997	0.000
E32.0 Persistent hyperplasia of thymus	0.003	0.997	0.000
E34.9 Endocrine disorder, unspecified	0.003	0.997	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.003	0.997	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.003	0.997	0.000
E24.9 Cushing's syndrome, unspecified	0.003	0.997	0.000
T15.9 Foreign body on external eye, unspecified	0.003	0.997	0.000
E53 Deficiency of other B group vitamins	0.003	0.997	0.000
M21.1 Varus deformity, not elsewhere classified	0.003	0.997	0.000
E21.0 Primary hyperparathyroidism	0.003	0.997	0.000
T15.0 Foreign body in cornea	0.003	0.997	0.000
T17 Foreign body in respiratory tract	0.003	0.997	0.000
E25.9 Adrenogenital disorder, unspecified	0.003	0.997	0.000
E25.8 Other adrenogenital disorders	0.003	0.997	0.000
S81.8 Open wound of other parts of lower leg	0.000	0.997	0.003
E34.5 Androgen resistance syndrome	0.003	0.997	0.000
E34.4 Constitutional tall stature	0.003	0.997	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.003	0.997	0.000
E34.1 Other hypersecretion of intestinal hormones	0.003	0.997	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.997	0.003
E28 Ovarian dysfunction	0.003	0.997	0.000
E23 Hypofunction and other disorders of pituitary gland	0.003	0.997	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
H90.5 Sensorineural hearing loss, unspecified	0.003	0.997	0.000
O43.8 Other placental disorders	0.000	0.997	0.003
T15.8 Foreign body in other and multiple parts of external eye	0.002	0.997	0.000
T15.1 Foreign body in conjunctival sac	0.002	0.997	0.000
N04 Nephrotic syndrome	0.003	0.997	0.000
Z50.0 Cardiac rehabilitation	0.003	0.997	0.000
E22 Hyperfunction of pituitary gland	0.003	0.997	0.000
I78 Diseases of capillaries	0.000	0.997	0.003
E53.9 Vitamin B deficiency, unspecified	0.003	0.997	0.000
E55 Vitamin D deficiency	0.002	0.997	0.000
T19 Foreign body in genito-urinary tract	0.002	0.997	0.000
G70.8 Other specified myoneural disorders	0.002	0.997	0.000
G70.2 Congenital and developmental myasthenia	0.002	0.997	0.000
G70.1 Toxic myoneural disorders	0.002	0.997	0.000
N04.1 Focal and segmental glomerular lesions	0.002	0.997	0.000
I44 Atrioventricular and left bundle-branch block	0.003	0.997	0.000
D14.0 Middle ear, nasal cavity and accessory sinuses	0.003	0.997	0.000
E34.8 Other specified endocrine disorders	0.002	0.997	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.002	0.997	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.000	0.997	0.002
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.000	0.997	0.002
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.000	0.997	0.002
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.997	0.002
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.997	0.002
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.002
M23.50 Chronic instability of knee (Multiple sites)	0.000	0.997	0.002
E29.8 Other testicular dysfunction	0.002	0.997	0.000
E29.0 Testicular hyperfunction	0.002	0.997	0.000
E29.9 Testicular dysfunction, unspecified	0.002	0.997	0.000
I77.0 Arteriovenous fistula, acquired	0.000	0.997	0.002
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.000	0.997	0.003
E61 Deficiency of other nutrient elements	0.002	0.997	0.000
E21.4 Other specified disorders of parathyroid gland	0.002	0.998	0.000
N04.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
E10.1 With ketoacidosis	0.002	0.998	0.000
C92.4 Acute promyelocytic leukaemia	0.002	0.998	0.000
T17.8 Foreign body in other and multiple parts of respiratory tract	0.002	0.998	0.000
A87.8 Other viral meningitis	0.002	0.998	0.000
A87.2 Lymphocytic choriomeningitis	0.002	0.998	0.000
A87.1 Adenoviral meningitis	0.002	0.998	0.000
A87.0 Enteroviral meningitis	0.002	0.998	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
M21.24 Flexion deformity (Hand)	0.002	0.998	0.000
E21.2 Other hyperparathyroidism	0.002	0.998	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.998	0.002
I42.9 Cardiomyopathy, unspecified	0.002	0.998	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.002	0.998	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.002	0.998	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.002	0.998	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
E53.1 Pyridoxine deficiency	0.002	0.998	0.000
E53.0 Riboflavin deficiency	0.002	0.998	0.000
E66 Obesity	0.002	0.998	0.000
M21.26 Flexion deformity (Lower leg)	0.002	0.998	0.000
S82.10 Fracture of upper end of tibia (closed)	0.002	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.002	0.998	0.000
M21.2 Flexion deformity	0.002	0.998	0.000
T17.4 Foreign body in trachea	0.002	0.998	0.000
T17.1 Foreign body in nostril	0.002	0.998	0.000
T17.0 Foreign body in nasal sinus	0.002	0.998	0.000
E22.0 Acromegaly and pituitary gigantism	0.002	0.998	0.000
E84.9 Cystic fibrosis, unspecified	0.002	0.998	0.000
E28.9 Ovarian dysfunction, unspecified	0.002	0.998	0.000
E28.8 Other ovarian dysfunction	0.002	0.998	0.000
E28.1 Androgen excess	0.002	0.998	0.000
E28.0 Oestrogen excess	0.002	0.998	0.000
E16.2 Hypoglycaemia, unspecified	0.002	0.998	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.002	0.998	0.000
E23.1 Drug-induced hypopituitarism	0.002	0.998	0.000
T17.3 Foreign body in larynx	0.002	0.998	0.000
T17.2 Foreign body in pharynx	0.002	0.998	0.000
E23.0 Hypopituitarism	0.002	0.998	0.000
E66.0 Obesity due to excess calories	0.002	0.998	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.002	0.998	0.000
T17.5 Foreign body in bronchus	0.002	0.998	0.000
E74 Other disorders of carbohydrate metabolism	0.002	0.998	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.002	0.998	0.000
E22.8 Other hyperfunction of pituitary gland	0.002	0.998	0.000
I78.9 Disease of capillaries, unspecified	0.000	0.998	0.002
N04.8 Other	0.002	0.998	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.002	0.998	0.000
N04.6 Dense deposit disease	0.002	0.998	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.998	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.998	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.998	0.000
M21 Other acquired deformities of limbs	0.002	0.998	0.000
E55.0 Rickets, active	0.002	0.998	0.000
M21.0 Valgus deformity, not elsewhere classified	0.002	0.998	0.000
E23.2 Diabetes insipidus	0.002	0.998	0.000
T19.9 Foreign body in genito-urinary tract, part unspecified	0.002	0.998	0.000
T19.8 Foreign body in other and multiple parts of genito-urinary tract	0.002	0.998	0.000
T19.3 Foreign body in uterus [any part]	0.002	0.998	0.000
T19.0 Foreign body in urethra	0.002	0.998	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.002	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.002	0.998	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.002	0.998	0.000
I78.8 Other diseases of capillaries	0.000	0.998	0.002
C71 Malignant neoplasm of brain	0.000	0.998	0.002
E28.3 Primary ovarian failure	0.002	0.998	0.000
I44.5 Left posterior fascicular block	0.002	0.998	0.000
E27 Other disorders of adrenal gland	0.002	0.998	0.000
E34.0 Carcinoid syndrome	0.002	0.998	0.000
T19.1 Foreign body in bladder	0.002	0.998	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.002	0.998	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.002	0.998	0.000
E61.9 Deficiency of nutrient element, unspecified	0.002	0.998	0.000
E61.8 Deficiency of other specified nutrient elements	0.002	0.998	0.000
E61.7 Deficiency of multiple nutrient elements	0.002	0.998	0.000
E61.6 Vanadium deficiency	0.002	0.998	0.000
E61.5 Molybdenum deficiency	0.002	0.998	0.000
E61.4 Chromium deficiency	0.002	0.998	0.000
E61.3 Manganese deficiency	0.002	0.998	0.000
E61.0 Copper deficiency	0.002	0.998	0.000
M21.7 Unequal limb length (acquired)	0.002	0.998	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.002	0.998	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M21.22 Flexion deformity (Upper arm)	0.002	0.998	0.000
C71.0 Cerebrum, except lobes and ventricles	0.000	0.998	0.002
E23.6 Other disorders of pituitary gland	0.002	0.998	0.000
E27.9 Disorder of adrenal gland, unspecified	0.002	0.998	0.000
N04.0 Minor glomerular abnormality	0.002	0.998	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.002	0.998	0.000
M21.9 Acquired deformity of limb, unspecified	0.002	0.998	0.000
E66.1 Drug-induced obesity	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations