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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12521584
log Bayes Factor = 17.302
Chromosome 5   position 39,568,215  (GRCh37) Explore rs12521584 on Ensembl!
Variant rs12521584 is part of Cluster X0150

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
N30-N39 Other diseases of urinary system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
N39 Other disorders of urinary system
0.993 0.007 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.992 0.008 0.000
I20 Angina pectoris
0.992 0.008 0.000
N39.0 Urinary tract infection, site not specified
0.989 0.011 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.986 0.014 0.000
Chapter X Diseases of the respiratory system
0.986 0.014 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.984 0.016 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.978 0.022 0.000
I25.2 Old myocardial infarction
0.976 0.024 0.000
Chapter XX External causes of morbidity and mortality
0.972 0.028 0.000
N35 Urethral stricture
0.967 0.033 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.966 0.034 0.000
J20-J22 Other acute lower respiratory infections
0.965 0.035 0.000
I20.9 Angina pectoris, unspecified
0.962 0.038 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.962 0.038 0.000
Chapter VIII Diseases of the ear and mastoid process
0.956 0.044 0.000
I30-I52 Other forms of heart disease
0.954 0.046 0.000
J22 Unspecified acute lower respiratory infection
0.951 0.049 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.950 0.050 0.000
N35.9 Urethral stricture, unspecified
0.943 0.057 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.943 0.057 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.943 0.057 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.941 0.059 0.000
N92 Excessive, frequent and irregular menstruation
0.940 0.060 0.000
I22 Subsequent myocardial infarction
0.933 0.067 0.000
I80 Phlebitis and thrombophlebitis
0.931 0.069 0.000
I84 Haemorrhoids
0.929 0.071 0.000
I20.0 Unstable angina
0.923 0.077 0.000
E70-E90 Metabolic disorders
0.923 0.077 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.919 0.081 0.000
W00-W19 Falls
0.914 0.086 0.000
Chapter XXI Factors influencing health status and contact with health services
0.912 0.088 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.910 0.090 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.910 0.090 0.000
M15-M19 Arthrosis
0.907 0.093 0.000
I84.6 Residual haemorrhoidal skin tags
0.907 0.093 0.000
M05-M14 Inflammatory polyarthropathies
0.905 0.095 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.904 0.096 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.893 0.107 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.889 0.111 0.000
H90-H95 Other disorders of ear
0.887 0.113 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.887 0.113 0.000
R30-R39 Symptoms and signs involving the urinary system
0.885 0.115 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.883 0.117 0.000
N10-N16 Renal tubulo-interstitial diseases
0.882 0.118 0.000
S20-S29 Injuries to the thorax
0.880 0.120 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.878 0.122 0.000
N17-N19 Renal failure
0.871 0.129 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.870 0.130 0.000
I21 Acute myocardial infarction
0.870 0.130 0.000
I35 Nonrheumatic aortic valve disorders
0.867 0.133 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.867 0.133 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.867 0.133 0.000
W19 Unspecified fall
0.866 0.134 0.000
M19 Other arthrosis
0.865 0.135 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.865 0.135 0.000
M45-M49 Spondylopathies
0.854 0.146 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.853 0.147 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.853 0.147 0.000
I50 Heart failure
0.853 0.147 0.000
M06 Other rheumatoid arthritis
0.852 0.148 0.000
N93 Other abnormal uterine and vaginal bleeding
0.850 0.150 0.000
Chapter V Mental and behavioural disorders
0.850 0.150 0.000
N36 Other disorders of urethra
0.849 0.151 0.000
S70-S79 Injuries to the hip and thigh
0.847 0.153 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.846 0.153 0.000
Chapter I Certain infectious and parasitic diseases
0.844 0.156 0.000
D50-D53 Nutritional anaemias
0.842 0.158 0.000
J40-J47 Chronic lower respiratory diseases
0.842 0.158 0.000
I05-I09 Chronic rheumatic heart diseases
0.840 0.160 0.000
I24 Other acute ischaemic heart diseases
0.840 0.160 0.000
T66-T78 Other and unspecified effects of external causes
0.839 0.161 0.000
E87.6 Hypokalaemia
0.839 0.161 0.000
R03.1 Nonspecific low blood-pressure reading
0.834 0.166 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.833 0.167 0.000
R42 Dizziness and giddiness
0.832 0.168 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.829 0.171 0.000
J44 Other chronic obstructive pulmonary disease
0.829 0.171 0.000
N32 Other disorders of bladder
0.828 0.172 0.000
Chapter VI Diseases of the nervous system
0.828 0.172 0.000
Z98 Other postsurgical states
0.827 0.173 0.000
N39.9 Disorder of urinary system, unspecified
0.826 0.174 0.000
N95 Menopausal and other perimenopausal disorders
0.821 0.179 0.000
N40-N51 Diseases of male genital organs
0.821 0.179 0.000
I34 Nonrheumatic mitral valve disorders
0.821 0.179 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.820 0.180 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.817 0.183 0.000
M19.9 Arthrosis, unspecified
0.815 0.185 0.000
I26 Pulmonary embolism
0.814 0.186 0.000
N99-N99 Other disorders of the genitourinary system
0.814 0.186 0.000
N92.6 Irregular menstruation, unspecified
0.813 0.187 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.812 0.188 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.810 0.190 0.000
M80-M85 Disorders of bone density and structure
0.808 0.192 0.000
S00-S09 Injuries to the head
0.807 0.193 0.000
R04 Haemorrhage from respiratory passages
0.807 0.193 0.000
I21.9 Acute myocardial infarction, unspecified
0.804 0.196 0.000
N86 Erosion and ectropion of cervix uteri
0.801 0.199 0.000
I42 Cardiomyopathy
0.800 0.200 0.000
D50 Iron deficiency anaemia
0.800 0.200 0.000
M06.9 Rheumatoid arthritis, unspecified
0.799 0.201 0.000
R31 Unspecified haematuria
0.799 0.201 0.000
H91 Other hearing loss
0.798 0.202 0.000
Z96 Presence of other functional implants
0.798 0.202 0.000
I25.1 Atherosclerotic heart disease
0.794 0.206 0.000
N25-N29 Other disorders of kidney and ureter
0.793 0.207 0.000
R35 Polyuria
0.793 0.207 0.000
Chapter XXII Codes for special purposes
0.791 0.209 0.000
N90.7 Vulvar cyst
0.790 0.210 0.000
N39.8 Other specified disorders of urinary system
0.786 0.214 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.785 0.215 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.785 0.215 0.000
W19.9 Unspecified place
0.784 0.216 0.000
J60-J70 Lung diseases due to external agents
0.784 0.216 0.000
Z93 Artificial opening status
0.780 0.220 0.000
N95.2 Postmenopausal atrophic vaginitis
0.778 0.222 0.000
M18 Arthrosis of first carpometacarpal joint
0.777 0.223 0.000
S60-S69 Injuries to the wrist and hand
0.777 0.223 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.776 0.224 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.776 0.224 0.000
N18 Chronic renal failure
0.774 0.226 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.772 0.228 0.000
T93 Sequelae of injuries of lower limb
0.772 0.228 0.000
E20-E35 Disorders of other endocrine glands
0.771 0.229 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.769 0.230 0.000
Z97 Presence of other devices
0.769 0.231 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.769 0.231 0.000
I20.8 Other forms of angina pectoris
0.766 0.233 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.765 0.235 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.764 0.236 0.000
Z96.6 Presence of orthopaedic joint implants
0.764 0.236 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.763 0.237 0.000
H65-H75 Diseases of middle ear and mastoid
0.761 0.239 0.000
E83 Disorders of mineral metabolism
0.760 0.240 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.758 0.242 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.757 0.243 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.755 0.245 0.000
R45 Symptoms and signs involving emotional state
0.754 0.245 0.000
M47 Spondylosis
0.754 0.246 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.753 0.247 0.000
I25.5 Ischaemic cardiomyopathy
0.753 0.247 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.753 0.247 0.000
N88 Other noninflammatory disorders of cervix uteri
0.751 0.249 0.000
N13 Obstructive and reflux uropathy
0.751 0.249 0.000
Z87 Personal history of other diseases and conditions
0.749 0.251 0.000
J81 Pulmonary oedema
0.748 0.252 0.000
H80-H83 Diseases of inner ear
0.747 0.252 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.747 0.253 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.746 0.254 0.000
Z98.0 Intestinal bypass and anastomosis status
0.745 0.255 0.000
N84 Polyp of female genital tract
0.745 0.255 0.000
R33 Retention of urine
0.745 0.255 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.745 0.255 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.743 0.257 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.743 0.257 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.742 0.258 0.000
N41 Inflammatory diseases of prostate
0.742 0.258 0.000
Z22 Carrier of infectious disease
0.740 0.260 0.000
W19.4 Street and highway
0.739 0.261 0.000
S80-S89 Injuries to the knee and lower leg
0.738 0.262 0.000
S72 Fracture of femur
0.738 0.262 0.000
T79-T79 Certain early complications of trauma
0.736 0.264 0.000
M91-M94 Chondropathies
0.736 0.264 0.000
I35.0 Aortic (valve) stenosis
0.735 0.265 0.000
H91.9 Hearing loss, unspecified
0.734 0.266 0.000
H60-H62 Diseases of external ear
0.734 0.266 0.000
E87.2 Acidosis
0.734 0.266 0.000
H92 Otalgia and effusion of ear
0.734 0.266 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.734 0.266 0.000
J00-J06 Acute upper respiratory infections
0.733 0.267 0.000
N30 Cystitis
0.732 0.268 0.000
N39.4 Other specified urinary incontinence
0.732 0.268 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.732 0.268 0.000
I33 Acute and subacute endocarditis
0.731 0.269 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.731 0.269 0.000
M19.1 Posttraumatic arthrosis of other joints
0.730 0.270 0.000
I84.4 External haemorrhoids with other complications
0.730 0.270 0.000
I84.9 Unspecified haemorrhoids without complication
0.730 0.270 0.000
I08 Multiple valve diseases
0.729 0.271 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.729 0.271 0.000
I50.0 Congestive heart failure
0.728 0.272 0.000
N90.5 Atrophy of vulva
0.727 0.272 0.000
R41.0 Disorientation, unspecified
0.727 0.273 0.000
R40 Somnolence, stupor and coma
0.726 0.274 0.000
T78 Adverse effects, not elsewhere classified
0.724 0.276 0.000
R07 Pain in throat and chest
0.724 0.276 0.000
J09-J18 Influenza and pneumonia
0.724 0.276 0.000
I34.0 Mitral (valve) insufficiency
0.723 0.277 0.000
S20 Superficial injury of thorax
0.723 0.277 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.722 0.278 0.000
I85 Oesophageal varices
0.722 0.278 0.000
T17 Foreign body in respiratory tract
0.721 0.279 0.000
A30-A49 Other bacterial diseases
0.721 0.279 0.000
R00 Abnormalities of heart beat
0.720 0.280 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.719 0.281 0.000
E87.0 Hyperosmolality and hypernatraemia
0.719 0.281 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.719 0.281 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.718 0.282 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N37 Urethral disorders in diseases classified elsewhere
0.717 0.283 0.000
N34 Urethritis and urethral syndrome
0.717 0.283 0.000
N33 Bladder disorders in diseases classified elsewhere
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S90-S99 Injuries to the ankle and foot
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.716 0.284 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
I25.3 Aneurysm of heart
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.715 0.285 0.000
N36.8 Other specified disorders of urethra
0.715 0.285 0.000
N39.2 Orthostatic proteinuria, unspecified
0.712 0.288 0.000
N39.1 Persistent proteinuria, unspecified
0.712 0.288 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.712 0.288 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.712 0.288 0.000
M50-M54 Other dorsopathies
0.711 0.289 0.000
I20.1 Angina pectoris with documented spasm
0.711 0.289 0.000
D50.9 Iron deficiency anaemia, unspecified
0.711 0.289 0.000
I86 Varicose veins of other sites
0.711 0.289 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.711 0.289 0.000
S40-S49 Injuries to the shoulder and upper arm
0.710 0.290 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.708 0.292 0.000
N98 Complications associated with artificial fertilisation
0.707 0.293 0.000
N91 Absent, scanty and rare menstruation
0.707 0.293 0.000
N82 Fistulae involving female genital tract
0.707 0.293 0.000
N96 Habitual aborter
0.707 0.293 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.707 0.293 0.000
W20-W49 Exposure to inanimate mechanical forces
0.707 0.293 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.707 0.293 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.705 0.295 0.000
M60-M63 Disorders of muscles
0.705 0.295 0.000
M00-M03 Infectious arthropathies
0.705 0.295 0.000
R41.3 Other amnesia
0.705 0.295 0.000
N43 Hydrocele and spermatocele
0.705 0.295 0.000
E50-E64 Other nutritional deficiencies
0.703 0.297 0.000
I50.1 Left ventricular failure
0.703 0.297 0.000
J84 Other interstitial pulmonary diseases
0.703 0.297 0.000
I35.9 Aortic valve disorder, unspecified
0.702 0.298 0.000
N19 Unspecified renal failure
0.702 0.298 0.000
I88 Nonspecific lymphadenitis
0.701 0.299 0.000
I87 Other disorders of veins
0.701 0.299 0.000
I82 Other venous embolism and thrombosis
0.701 0.299 0.000
I81 Portal vein thrombosis
0.701 0.299 0.000
R04.2 Haemoptysis
0.700 0.300 0.000
I21.4 Acute subendocardial myocardial infarction
0.700 0.300 0.000
V10-V19 Pedal cyclist injured in transport accident
0.700 0.300 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.699 0.301 0.000
N92.3 Ovulation bleeding
0.699 0.301 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.698 0.302 0.000
Z98.8 Other specified postsurgical states
0.697 0.303 0.000
X60-X84 Intentional self-harm
0.697 0.303 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.697 0.303 0.000
Y35-Y36 Legal intervention and operations of war
0.697 0.303 0.000
Y10-Y34 Event of undetermined intent
0.697 0.303 0.000
Y00-Y09 Assault
0.697 0.303 0.000
X85-X99 Assault
0.697 0.303 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.697 0.303 0.000
X50-X57 Overexertion, travel and privation
0.697 0.303 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.697 0.303 0.000
X30-X39 Exposure to forces of nature
0.697 0.303 0.000
X20-X29 Contact with venomous animals and plants
0.697 0.303 0.000
X10-X19 Contact with heat and hot substances
0.697 0.303 0.000
X00-X09 Exposure to smoke, fire and flames
0.697 0.303 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.697 0.303 0.000
W75-W84 Other accidental threats to breathing
0.697 0.303 0.000
W65-W74 Accidental drowning and submersion
0.697 0.303 0.000
W50-W64 Exposure to animate mechanical forces
0.697 0.303 0.000
V98-V99 Other and unspecified transport accidents
0.697 0.303 0.000
V95-V97 Air and space transport accidents
0.697 0.303 0.000
V90-V94 Water transport accidents
0.697 0.303 0.000
V80-V89 Other land transport accidents
0.697 0.303 0.000
V70-V79 Bus occupant injured in transport accident
0.697 0.303 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.697 0.303 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.697 0.303 0.000
V40-V49 Car occupant injured in transport accident
0.697 0.303 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.697 0.303 0.000
V20-V29 Motorcycle rider injured in transport accident
0.697 0.303 0.000
V01-V09 Pedestrian injured in transport accident
0.697 0.303 0.000
E88 Other metabolic disorders
0.695 0.305 0.000
S06 Intracranial injury
0.694 0.306 0.000
N35.8 Other urethral stricture
0.693 0.307 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.693 0.307 0.000
N35.0 Posttraumatic urethral stricture
0.693 0.307 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.693 0.307 0.000
J21 Acute bronchiolitis
0.692 0.308 0.000
J20 Acute bronchitis
0.692 0.308 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.692 0.308 0.000
W07 Fall involving chair
0.692 0.308 0.000
G30-G32 Other degenerative diseases of the nervous system
0.691 0.309 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.690 0.310 0.000
R46 Symptoms and signs involving appearance and behaviour
0.690 0.310 0.000
R43 Disturbances of smell and taste
0.690 0.310 0.000
I84.5 External haemorrhoids without complication
0.690 0.310 0.000
R01 Cardiac murmurs and other cardiac sounds
0.689 0.311 0.000
M86-M90 Other osteopathies
0.689 0.311 0.000
N00-N08 Glomerular diseases
0.689 0.311 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.688 0.311 0.000
M16 Coxarthrosis [arthrosis of hip]
0.688 0.312 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.688 0.312 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.686 0.314 0.000
I49 Other cardiac arrhythmias
0.686 0.314 0.000
R47-R49 Symptoms and signs involving speech and voice
0.686 0.314 0.000
Z83 Family history of other specific disorders
0.684 0.316 0.000
I52 Other heart disorders in diseases classified elsewhere
0.684 0.316 0.000
I48 Atrial fibrillation and flutter
0.684 0.316 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.684 0.316 0.000
I41 Myocarditis in diseases classified elsewhere
0.684 0.316 0.000
I40 Acute myocarditis
0.684 0.316 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.684 0.316 0.000
I37 Pulmonary valve disorders
0.684 0.316 0.000
I36 Nonrheumatic tricuspid valve disorders
0.684 0.316 0.000
I32 Pericarditis in diseases classified elsewhere
0.684 0.316 0.000
I30 Acute pericarditis
0.684 0.316 0.000
I38 Endocarditis, valve unspecified
0.684 0.316 0.000
I24.8 Other forms of acute ischaemic heart disease
0.684 0.316 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.684 0.316 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.683 0.317 0.000
M10 Gout
0.683 0.317 0.000
Z22.3 Carrier of other specified bacterial diseases
0.682 0.318 0.000
Z80 Family history of malignant neoplasm
0.681 0.319 0.000
T87 Complications peculiar to reattachment and amputation
0.681 0.319 0.000
T86 Failure and rejection of transplanted organs and tissues
0.681 0.319 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.681 0.319 0.000
S62 Fracture at wrist and hand level
0.681 0.319 0.000
I42.0 Dilated cardiomyopathy
0.681 0.319 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.680 0.320 0.000
M06.0 Seronegative rheumatoid arthritis
0.680 0.320 0.000
I46 Cardiac arrest
0.678 0.321 0.000
B95-B98 Bacterial, viral and other infectious agents
0.678 0.321 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.678 0.322 0.000
T88.4 Failed or difficult intubation
0.678 0.322 0.000
H90 Conductive and sensorineural hearing loss
0.677 0.323 0.000
S00 Superficial injury of head
0.676 0.324 0.000
N93.0 Postcoital and contact bleeding
0.676 0.324 0.000
Z93.6 Other artificial openings of urinary tract status
0.675 0.325 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.675 0.325 0.000
E40-E46 Malnutrition
0.675 0.325 0.000
N92.5 Other specified irregular menstruation
0.674 0.326 0.000
N92.2 Excessive menstruation at puberty
0.674 0.326 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.674 0.326 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.673 0.327 0.000
M40-M43 Deforming dorsopathies
0.673 0.327 0.000
N84.1 Polyp of cervix uteri
0.672 0.328 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.672 0.328 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.671 0.329 0.000
R10 Abdominal and pelvic pain
0.670 0.330 0.000
I51 Complications and ill-defined descriptions of heart disease
0.670 0.330 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.670 0.330 0.000
I22.8 Subsequent myocardial infarction of other sites
0.669 0.331 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.669 0.331 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.667 0.333 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.667 0.333 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.667 0.333 0.000
N92.4 Excessive bleeding in the premenopausal period
0.667 0.333 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.667 0.333 0.000
M19.94 Arthrosis, unspecified (Hand)
0.666 0.334 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.666 0.334 0.000
I84.3 External thrombosed haemorrhoids
0.666 0.334 0.000
I84.0 Internal thrombosed haemorrhoids
0.666 0.334 0.000
N32.3 Diverticulum of bladder
0.666 0.334 0.000
W19.2 School, other institution and public administrative area
0.666 0.334 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.666 0.334 0.000
D50.8 Other iron deficiency anaemias
0.665 0.335 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.665 0.335 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.663 0.337 0.000
E85 Amyloidosis
0.661 0.338 0.000
E84 Cystic fibrosis
0.661 0.338 0.000
E79 Disorders of purine and pyrimidine metabolism
0.661 0.338 0.000
E77 Disorders of glycoprotein metabolism
0.661 0.338 0.000
E76 Disorders of glycosaminoglycan metabolism
0.661 0.338 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.661 0.338 0.000
E74 Other disorders of carbohydrate metabolism
0.661 0.338 0.000
E73 Lactose intolerance
0.661 0.338 0.000
E72 Other disorders of amino-acid metabolism
0.661 0.338 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.661 0.338 0.000
E70 Disorders of aromatic amino-acid metabolism
0.661 0.338 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.661 0.338 0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.659 0.341 0.000
N90.6 Hypertrophy of vulva
0.659 0.341 0.000
N90.4 Leukoplakia of vulva
0.659 0.341 0.000
N90.3 Dysplasia of vulva, unspecified
0.659 0.341 0.000
N90.2 Severe vulvar dysplasia, not elsewhere classified
0.659 0.341 0.000
N90.1 Moderate vulvar dysplasia
0.659 0.341 0.000
N90.0 Mild vulvar dysplasia
0.659 0.341 0.000
Y85 Sequelae of transport accidents
0.658 0.342 0.000
R00.2 Palpitations
0.658 0.342 0.000
N36.2 Urethral caruncle
0.657 0.343 0.000
R02 Gangrene, not elsewhere classified
0.657 0.343 0.000
N18.3 Chronic kidney disease, stage 3
0.657 0.343 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.657 0.343 0.000
M20-M25 Other joint disorders
0.656 0.344 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.656 0.344 0.000
W18 Other fall on same level
0.655 0.344 0.000
W17 Other fall from one level to another
0.655 0.344 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.655 0.344 0.000
W15 Fall from cliff
0.655 0.344 0.000
W14 Fall from tree
0.655 0.344 0.000
W13 Fall from, out of or through building or structure
0.655 0.344 0.000
W12 Fall on and from scaffolding
0.655 0.344 0.000
W11 Fall on and from ladder
0.655 0.344 0.000
W10 Fall on and from stairs and steps
0.655 0.344 0.000
W09 Fall involving playground equipment
0.655 0.344 0.000
W08 Fall involving other furniture
0.655 0.344 0.000
W06 Fall involving bed
0.655 0.344 0.000
W05 Fall involving wheelchair
0.655 0.344 0.000
W04 Fall while being carried or supported by other persons
0.655 0.344 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.655 0.344 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.655 0.344 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.655 0.344 0.000
W00 Fall on same level involving ice and snow
0.655 0.344 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.655 0.345 0.000
S27 Injury of other and unspecified intrathoracic organs
0.655 0.345 0.000
D51 Vitamin B12 deficiency anaemia
0.654 0.346 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.653 0.347 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.653 0.347 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.653 0.347 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.653 0.347 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.653 0.347 0.000
T83.2 Mechanical complication of graft of urinary organ
0.653 0.347 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.653 0.347 0.000
E87.7 Fluid overload
0.653 0.347 0.000
E87.4 Mixed disorder of acid-base balance
0.653 0.347 0.000
E87.3 Alkalosis
0.653 0.347 0.000
M81 Osteoporosis without pathological fracture
0.651 0.349 0.000
M15 Polyarthrosis
0.651 0.349 0.000
Z96.0 Presence of urogenital implants
0.650 0.350 0.000
M14 Arthropathies in other diseases classified elsewhere
0.649 0.351 0.000
M12 Other specific arthropathies
0.649 0.351 0.000
M11 Other crystal arthropathies
0.649 0.351 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.649 0.351 0.000
M08 Juvenile arthritis
0.649 0.351 0.000
M07 Psoriatic and enteropathic arthropathies
0.649 0.351 0.000
M05 Seropositive rheumatoid arthritis
0.649 0.351 0.000
M47.9 Spondylosis, unspecified
0.649 0.351 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.649 0.351 0.000
Z94 Transplanted organ and tissue status
0.648 0.352 0.000
I27 Other pulmonary heart diseases
0.648 0.352 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.645 0.355 0.000
M65-M68 Disorders of synovium and tendon
0.645 0.355 0.000
N40 Hyperplasia of prostate
0.645 0.355 0.000
R10.1 Pain localised to upper abdomen
0.644 0.356 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.643 0.357 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.643 0.357 0.000
I28 Other diseases of pulmonary vessels
0.640 0.360 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.640 0.360 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.640 0.360 0.000
N32.8 Other specified disorders of bladder
0.640 0.360 0.000
Z89 Acquired absence of limb
0.638 0.362 0.000
Z84 Family history of other conditions
0.638 0.362 0.000
Z81 Family history of mental and behavioural disorders
0.638 0.362 0.000
T18 Foreign body in alimentary tract
0.638 0.362 0.000
T78.2 Anaphylactic shock, unspecified
0.637 0.362 0.000
I35.1 Aortic (valve) insufficiency
0.637 0.363 0.000
D52 Folate deficiency anaemia
0.636 0.363 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.636 0.364 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.636 0.364 0.000
I84.1 Internal haemorrhoids with other complications
0.636 0.364 0.000
M48 Other spondylopathies
0.636 0.364 0.000
R41.2 Retrograde amnesia
0.636 0.364 0.000
R41.1 Anterograde amnesia
0.636 0.364 0.000
Z97.8 Presence of other specified devices
0.636 0.364 0.000
S02 Fracture of skull and facial bones
0.635 0.365 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.635 0.365 0.000
R36 Urethral discharge
0.635 0.365 0.000
R34 Anuria and oliguria
0.635 0.365 0.000
J95-J99 Other diseases of the respiratory system
0.634 0.366 0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)
0.633 0.367 0.000
Z93.1 Gastrostomy status
0.633 0.367 0.000
D55-D59 Haemolytic anaemias
0.633 0.367 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.633 0.367 0.000
N83.0 Follicular cyst of ovary
0.633 0.367 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.633 0.367 0.000
N15 Other renal tubulo-interstitial diseases
0.633 0.367 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.633 0.367 0.000
N11 Chronic tubulo-interstitial nephritis
0.633 0.367 0.000
N10 Acute tubulo-interstitial nephritis
0.633 0.367 0.000
N89 Other noninflammatory disorders of vagina
0.632 0.367 0.000
B35-B49 Mycoses
0.632 0.368 0.000
Z29 Need for other prophylactic measures
0.631 0.369 0.000
S29 Other and unspecified injuries of thorax
0.631 0.369 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.631 0.369 0.000
S26 Injury of heart
0.631 0.369 0.000
S25 Injury of blood vessels of thorax
0.631 0.369 0.000
S24 Injury of nerves and spinal cord at thorax level
0.631 0.369 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.631 0.369 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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