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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12529874
log Bayes Factor = 0.00852317
Chromosome 6   position 98,462,501  (GRCh37) Explore rs12529874 on Ensembl!
Variant rs12529874 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M50 Cervical disk disorders
0.026 0.974 0.000
M50.2 Other cervical disk displacement
0.026 0.974 0.000
M50.3 Other cervical disk degeneration
0.024 0.976 0.000
C79 Secondary malignant neoplasm of other sites
0.000 0.976 0.024
C78.0 Secondary malignant neoplasm of lung
0.000 0.976 0.024
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.000 0.976 0.023
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.000 0.977 0.023
D25.9 Leiomyoma of uterus, unspecified
0.000 0.977 0.023
M50.0 Cervical disk disorder with myelopathy
0.022 0.978 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.000 0.978 0.022
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.000 0.978 0.022
M50.9 Cervical disk disorder, unspecified
0.022 0.978 0.000
C77.3 Axillary and upper limb lymph nodes
0.000 0.979 0.021
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.000 0.979 0.021
C79.8 Secondary malignant neoplasm of other specified sites
0.000 0.979 0.021
M50-M54 Other dorsopathies
0.020 0.980 0.000
M50.1 Cervical disk disorder with radiculopathy
0.020 0.980 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.000 0.981 0.019
C78.2 Secondary malignant neoplasm of pleura
0.000 0.981 0.019
M50.8 Other cervical disk disorders
0.019 0.981 0.000
C77.5 Intrapelvic lymph nodes
0.000 0.981 0.019
M54 Dorsalgia
0.019 0.981 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.000 0.982 0.018
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.000 0.982 0.017
C77.4 Inguinal and lower limb lymph nodes
0.000 0.983 0.017
M54.4 Lumbago with sciatica
0.017 0.983 0.000
C79.2 Secondary malignant neoplasm of skin
0.000 0.983 0.016
C76 Malignant neoplasm of other and ill-defined sites
0.000 0.984 0.016
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.000 0.984 0.016
C78.1 Secondary malignant neoplasm of mediastinum
0.000 0.984 0.016
M54.3 Sciatica
0.016 0.984 0.000
M54.2 Cervicalgia
0.016 0.984 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.000 0.984 0.016
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.000 0.985 0.015
M53 Other dorsopathies, not elsewhere classified
0.015 0.985 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.000 0.985 0.015
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.000 0.985 0.015
C77.8 Lymph nodes of multiple regions
0.000 0.985 0.015
C77.0 Lymph nodes of head, face and neck
0.000 0.985 0.015
M54.36 Sciatica (Lumbar region)
0.015 0.985 0.000
C80 Malignant neoplasm without specification of site
0.000 0.985 0.015
M54.1 Radiculopathy
0.015 0.985 0.000
C78.7 Secondary malignant neoplasm of liver
0.000 0.985 0.015
M54.22 Cervicalgia (Cervical region)
0.015 0.985 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.015 0.985 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.000 0.986 0.014
M54.46 Lumbago with sciatica (Lumbar region)
0.014 0.986 0.000
C79.6 Secondary malignant neoplasm of ovary
0.000 0.986 0.014
M51 Other intervertebral disk disorders
0.014 0.986 0.000
M54.6 Pain in thoracic spine
0.014 0.986 0.000
M54.8 Other dorsalgia
0.013 0.986 0.000
M54.0 Panniculitis affecting regions of neck and back
0.013 0.986 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.012 0.988 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.012 0.988 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.012 0.988 0.000
M54.44 Lumbago with sciatica-Thoracic
0.012 0.988 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.012 0.988 0.000
M54.42 Lumbago with sciatica-Cervical
0.012 0.988 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.012 0.988 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.012 0.988 0.000
M54.16 Radiculopathy (Lumbar region)
0.012 0.988 0.000
C76.8 Overlapping lesion of other and ill-defined sites
0.000 0.988 0.012
C76.7 Other ill-defined sites
0.000 0.988 0.012
C76.5 Lower limb
0.000 0.988 0.012
C76.4 Upper limb
0.000 0.988 0.012
C76.3 Pelvis
0.000 0.988 0.012
C76.2 Abdomen
0.000 0.988 0.012
C76.1 Thorax
0.000 0.988 0.012
C76.0 Head, face and neck
0.000 0.988 0.012
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.012 0.988 0.000
M54.37 Sciatica (Lumbosacral region)
0.012 0.988 0.000
M54.35 Sciatica (Thoracolumbar region)
0.012 0.988 0.000
M54.34 Sciatica-Thoracic
0.012 0.988 0.000
M54.33 Sciatica-Cervicothoracic
0.012 0.988 0.000
M54.32 Sciatica-Cervical
0.012 0.988 0.000
M54.31 Sciatica-Occipit-atl-axl
0.012 0.988 0.000
M54.30 Sciatica (Multiple sites in spine)
0.012 0.988 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.012 0.988 0.000
M54.27 Cervicalgia-Lumbosacral
0.012 0.988 0.000
M54.26 Cervicalgia-Lumbar
0.012 0.988 0.000
M54.25 Cervicalgia-Thoracolumbar
0.012 0.988 0.000
M54.24 Cervicalgia-Thoracic
0.012 0.988 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.012 0.988 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.012 0.988 0.000
M54.20 Cervicalgia-Mult site
0.012 0.988 0.000
C80.9 Malignant neoplasm, unspecified
0.000 0.988 0.012
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.012 0.988 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.000 0.988 0.012
M54.29 Cervicalgia-Site unspe
0.011 0.989 0.000
M53.9 Dorsopathy, unspecified
0.011 0.989 0.000
M53.8 Other specified dorsopathies
0.011 0.989 0.000
M53.2 Spinal instabilities
0.011 0.989 0.000
M53.1 Cervicobrachial syndrome
0.011 0.989 0.000
M53.0 Cervicocranial syndrome
0.011 0.989 0.000
M51.8 Other specified intervertebral disk disorders
0.011 0.989 0.000
M54.39 Sciatica (Site unspecified)
0.011 0.989 0.000
C77.9 Lymph node, unspecified
0.000 0.989 0.011
M54.19 Radiculopathy (Site unspecified)
0.011 0.989 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.011 0.989 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.011 0.989 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.011 0.989 0.000
M54.14 Radiculopathy (Thoracic region)
0.011 0.989 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.011 0.989 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.011 0.989 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.011 0.989 0.000
M54.12 Radiculopathy (Cervical region)
0.010 0.989 0.000
M54.9 Dorsalgia, unspecified
0.011 0.989 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.010 0.990 0.000
M51.3 Other specified intervertebral disk degeneration
0.010 0.990 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.010 0.990 0.000
M51.9 Intervertebral disk disorder, unspecified
0.010 0.990 0.000
M51.4 Schmorl's nodes
0.010 0.990 0.000
M54.69 Pain in thoracic spine-Site unspe
0.010 0.990 0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ
0.010 0.990 0.000
M54.67 Pain in thoracic spine-Lumbosacral
0.010 0.990 0.000
M54.66 Pain in thoracic spine-Lumbar
0.010 0.990 0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)
0.010 0.990 0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)
0.010 0.990 0.000
M54.62 Pain in thoracic spine-Cervical
0.010 0.990 0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl
0.010 0.990 0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)
0.010 0.990 0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)
0.010 0.990 0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)
0.010 0.990 0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)
0.010 0.990 0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)
0.010 0.990 0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)
0.010 0.990 0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)
0.010 0.990 0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)
0.010 0.990 0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)
0.010 0.990 0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)
0.010 0.990 0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)
0.010 0.990 0.000
M54.89 Other dorsalgia (Site unspecified)
0.010 0.990 0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)
0.010 0.990 0.000
M54.87 Other dorsalgia (Lumbosacral region)
0.010 0.990 0.000
M54.86 Other dorsalgia (Lumbar region)
0.010 0.990 0.000
M54.85 Other dorsalgia (Thoracolumbar region)
0.010 0.990 0.000
M54.84 Other dorsalgia (Thoracic region)
0.010 0.990 0.000
M54.83 Other dorsalgia (Cervicothoracic region)
0.010 0.990 0.000
M54.82 Other dorsalgia (Cervical region)
0.010 0.990 0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)
0.010 0.990 0.000
M54.80 Other dorsalgia (Multiple sites in spine)
0.010 0.990 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.009 0.991 0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s
0.009 0.991 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.009 0.991 0.000
C77.2 Intra-abdominal lymph nodes
0.000 0.991 0.009
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns
0.008 0.991 0.000
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac
0.008 0.991 0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar
0.008 0.991 0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol
0.008 0.991 0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic
0.008 0.991 0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot
0.008 0.991 0.000
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical
0.008 0.991 0.000
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-
0.008 0.991 0.000
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit
0.008 0.991 0.000
M51.2 Other specified intervertebral disk displacement
0.009 0.991 0.000
C77.1 Intrathoracic lymph nodes
0.000 0.992 0.008
M53.09 Cervicocranial syndrome-Site unspe
0.008 0.992 0.000
M53.08 Cervicocranial syndrome-Sacral/sacrococ
0.008 0.992 0.000
M53.07 Cervicocranial syndrome-Lumbosacral
0.008 0.992 0.000
M53.06 Cervicocranial syndrome-Lumbar
0.008 0.992 0.000
M53.05 Cervicocranial syndrome-Thoracolumbar
0.008 0.992 0.000
M53.04 Cervicocranial syndrome-Thoracic
0.008 0.992 0.000
M53.03 Cervicocranial syndrome (Cervicothoracic region)
0.008 0.992 0.000
M53.02 Cervicocranial syndrome (Cervical region)
0.008 0.992 0.000
M53.01 Cervicocranial syndrome (Occipito-atlanto-axial region)
0.008 0.992 0.000
M53.00 Cervicocranial syndrome (Multiple sites in spine)
0.008 0.992 0.000
M53.19 Cervicobrachial syndrome-Site unspe
0.008 0.992 0.000
M53.18 Cervicobrachial syndrome-Sacral/sacrococ
0.008 0.992 0.000
M53.17 Cervicobrachial syndrome-Lumbosacral
0.008 0.992 0.000
M53.16 Cervicobrachial syndrome-Lumbar
0.008 0.992 0.000
M53.15 Cervicobrachial syndrome-Thoracolumbar
0.008 0.992 0.000
M53.14 Cervicobrachial syndrome-Thoracic
0.008 0.992 0.000
M53.13 Cervicobrachial syndrome (Cervicothoracic region)
0.008 0.992 0.000
M53.12 Cervicobrachial syndrome (Cervical region)
0.008 0.992 0.000
M53.11 Cervicobrachial syndrome (Occipito-atlanto-axial region)
0.008 0.992 0.000
M53.10 Cervicobrachial syndrome (Multiple sites in spine)
0.008 0.992 0.000
M53.29 Spinal instabilities (Site unspecified)
0.008 0.992 0.000
M53.28 Spinal instabilities (Sacral and sacrococcygeal region)
0.008 0.992 0.000
M53.27 Spinal instabilities (Lumbosacral region)
0.008 0.992 0.000
M53.26 Spinal instabilities (Lumbar region)
0.008 0.992 0.000
M53.25 Spinal instabilities (Thoracolumbar region)
0.008 0.992 0.000
M53.24 Spinal instabilities (Thoracic region)
0.008 0.992 0.000
M53.23 Spinal instabilities (Cervicothoracic region)
0.008 0.992 0.000
M53.22 Spinal instabilities (Cervical region)
0.008 0.992 0.000
M53.21 Spinal instabilities (Occipito-atlanto-axial region)
0.008 0.992 0.000
M53.20 Spinal instabilities (Multiple sites in spine)
0.008 0.992 0.000
M53.89 Other specified dorsopathies (Site unspecified)
0.008 0.992 0.000
M53.88 Other specified dorsopathies (Sacral and sacrococcygeal region)
0.008 0.992 0.000
M53.87 Other specified dorsopathies (Lumbosacral region)
0.008 0.992 0.000
M53.86 Other specified dorsopathies (Lumbar region)
0.008 0.992 0.000
M53.85 Other specified dorsopathies (Thoracolumbar region)
0.008 0.992 0.000
M53.84 Other specified dorsopathies (Thoracic region)
0.008 0.992 0.000
M53.83 Other specified dorsopathies (Cervicothoracic region)
0.008 0.992 0.000
M53.82 Other specified dorsopathies (Cervical region)
0.008 0.992 0.000
M53.81 Other specified dorsopathies (Occipito-atlanto-axial region)
0.008 0.992 0.000
M53.80 Other specified dorsopathies (Multiple sites in spine)
0.008 0.992 0.000
M53.99 Dorsopathy, unspecified (Site unspecified)
0.008 0.992 0.000
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)
0.008 0.992 0.000
M53.97 Dorsopathy, unspecified (Lumbosacral region)
0.008 0.992 0.000
M53.96 Dorsopathy, unspecified (Lumbar region)
0.008 0.992 0.000
M53.95 Dorsopathy, unspecified (Thoracolumbar region)
0.008 0.992 0.000
M53.94 Dorsopathy, unspecified (Thoracic region)
0.008 0.992 0.000
M53.93 Dorsopathy, unspecified (Cervicothoracic region)
0.008 0.992 0.000
M53.92 Dorsopathy, unspecified (Cervical region)
0.008 0.992 0.000
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)
0.008 0.992 0.000
M53.90 Dorsopathy, unspecified (Multiple sites in spine)
0.008 0.992 0.000
M65-M68 Disorders of synovium and tendon
0.008 0.992 0.000
M80-M85 Disorders of bone density and structure
0.008 0.992 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.008 0.992 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.008 0.992 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.008 0.992 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.008 0.992 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.008 0.992 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.008 0.992 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.008 0.992 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.008 0.992 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.000 0.992 0.008
M54.5 Low back pain
0.008 0.992 0.000
M60-M63 Disorders of muscles
0.008 0.992 0.000
M86-M90 Other osteopathies
0.008 0.992 0.000
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified
0.007 0.992 0.000
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region
0.007 0.992 0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region
0.007 0.992 0.000
M35 Other systemic involvement of connective tissue
0.007 0.993 0.000
M35.0 Sicca syndrome [Sjogren]
0.007 0.993 0.000
F31 Bipolar affective disorder
0.007 0.993 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.007 0.993 0.000
M67 Other disorders of synovium and tendon
0.007 0.993 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.007 0.993 0.000
M84 Disorders of continuity of bone
0.007 0.993 0.000
M54.57 Low back pain (Lumbosacral region)
0.007 0.993 0.000
M65 Synovitis and tenosynovitis
0.007 0.993 0.000
M40-M43 Deforming dorsopathies
0.007 0.993 0.000
M62 Other disorders of muscle
0.007 0.993 0.000
M82 Osteoporosis in diseases classified elsewhere
0.007 0.993 0.000
M00-M03 Infectious arthropathies
0.007 0.993 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.007 0.993 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.007 0.993 0.000
F31.9 Bipolar affective disorder, unspecified
0.007 0.993 0.000
M20-M25 Other joint disorders
0.007 0.993 0.000
M05-M14 Inflammatory polyarthropathies
0.007 0.993 0.000
M35.7 Hypermobility syndrome
0.006 0.993 0.000
M66 Spontaneous rupture of synovium and tendon
0.006 0.993 0.000
M85 Other disorders of bone density and structure
0.006 0.993 0.000
M54.50 Low back pain (Multiple sites in spine)
0.006 0.994 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.006 0.994 0.000
M87 Osteonecrosis
0.006 0.994 0.000
M35.3 Polymyalgia rheumatica
0.006 0.994 0.000
M89 Other disorders of bone
0.006 0.994 0.000
M67.8 Other specified disorders of synovium and tendon
0.006 0.994 0.000
M91-M94 Chondropathies
0.006 0.994 0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.006 0.994 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.006 0.994 0.000
M81 Osteoporosis without pathological fracture
0.006 0.994 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.006 0.994 0.000
M62.8 Other specified disorders of muscle
0.006 0.994 0.000
M83 Adult osteomalacia
0.006 0.994 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.006 0.994 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.006 0.994 0.000
M07 Psoriatic and enteropathic arthropathies
0.006 0.994 0.000
D25 Leiomyoma of uterus
0.000 0.994 0.006
M24 Other specific joint derangements
0.006 0.994 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.006 0.994 0.000
M84.0 Malunion of fracture
0.006 0.994 0.000
M62.89 Other specified disorders of muscle (Site unspecified)
0.006 0.994 0.000
M54.55 Low back pain (Thoracolumbar region)
0.006 0.994 0.000
M54.54 Low back pain-Thoracic
0.006 0.994 0.000
M54.53 Low back pain-Cervicothoracic
0.006 0.994 0.000
M54.52 Low back pain-Cervical
0.006 0.994 0.000
M54.51 Low back pain-Occipit-atl-axl
0.006 0.994 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.006 0.994 0.000
M80 Osteoporosis with pathological fracture
0.006 0.994 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.006 0.994 0.000
M61 Calcification and ossification of muscle
0.006 0.994 0.000
M60 Myositis
0.006 0.994 0.000
M90 Osteopathies in diseases classified elsewhere
0.006 0.994 0.000
M88 Paget's disease of bone [osteitis deformans]
0.006 0.994 0.000
M65.8 Other synovitis and tenosynovitis
0.006 0.994 0.000
M65.1 Other infective (teno)synovitis
0.006 0.994 0.000
M82.1 Osteoporosis in endocrine disorders
0.006 0.994 0.000
M11 Other crystal arthropathies
0.006 0.994 0.000
M30 Polyarteritis nodosa and related conditions
0.006 0.994 0.000
M07.3 Other psoriatic arthropathies
0.006 0.994 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.005 0.994 0.000
M35.8 Other specified systemic involvement of connective tissue
0.005 0.994 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.005 0.994 0.000
M35.5 Multifocal fibrosclerosis
0.005 0.994 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.005 0.994 0.000
M35.2 Behcet's disease
0.005 0.994 0.000
M35.1 Other overlap syndromes
0.005 0.994 0.000
M86 Osteomyelitis
0.005 0.994 0.000
M67.1 Other contracture of tendon (sheath)
0.005 0.994 0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.005 0.994 0.000
F31.8 Other bipolar affective disorders
0.005 0.995 0.000
F31.7 Bipolar affective disorder, currently in remission
0.005 0.995 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.005 0.995 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.005 0.995 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.005 0.995 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.005 0.995 0.000
M99 Biomechanical lesions, not elsewhere classified
0.005 0.995 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.005 0.995 0.000
M67.4 Ganglion
0.005 0.995 0.000
M67.3 Transient synovitis
0.005 0.995 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.005 0.995 0.000
M67.0 Short Achilles tendon (acquired)
0.005 0.995 0.000
M87.9 Osteonecrosis, unspecified
0.005 0.995 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.005 0.995 0.000
M84.9 Disorder of continuity of bone, unspecified
0.005 0.995 0.000
M84.8 Other disorders of continuity of bone
0.005 0.995 0.000
M84.4 Pathological fracture, not elsewhere classified
0.005 0.995 0.000
M84.3 Stress fracture, not elsewhere classified
0.005 0.995 0.000
M84.2 Delayed union of fracture
0.005 0.995 0.000
M85.8 Other specified disorders of bone density and structure
0.005 0.995 0.000
M21 Other acquired deformities of limbs
0.005 0.995 0.000
M65.2 Calcific tendinitis
0.005 0.995 0.000
M65.0 Abscess of tendon sheath
0.005 0.995 0.000
M66.2 Spontaneous rupture of extensor tendons
0.005 0.995 0.000
M89.8 Other specified disorders of bone
0.005 0.995 0.000
M14 Arthropathies in other diseases classified elsewhere
0.005 0.995 0.000
M41 Scoliosis
0.005 0.995 0.000
M43 Other deforming dorsopathies
0.005 0.995 0.000
M42 Spinal osteochondrosis
0.005 0.995 0.000
M40 Kyphosis and lordosis
0.005 0.995 0.000
D25.1 Intramural leiomyoma of uterus
0.000 0.995 0.005
M62.9 Disorder of muscle, unspecified
0.005 0.995 0.000
M62.6 Muscle strain
0.005 0.995 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.005 0.995 0.000
M62.4 Contracture of muscle
0.005 0.995 0.000
M62.3 Immobility syndrome (paraplegic)
0.005 0.995 0.000
M62.2 Ischaemic infarction of muscle
0.005 0.995 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.005 0.995 0.000
M62.0 Diastasis of muscle
0.005 0.995 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.005 0.995 0.000
F30-F39 Mood [affective] disorders
0.005 0.995 0.000
M65.3 Trigger finger
0.005 0.995 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.005 0.995 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.005 0.995 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.005 0.995 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.005 0.995 0.000
M02 Reactive arthropathies
0.005 0.995 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.005 0.995 0.000
M00 Pyogenic arthritis
0.005 0.995 0.000
M84.03 Malunion of fracture (Forearm)
0.005 0.995 0.000
M81.9 Osteoporosis, unspecified
0.005 0.995 0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.005 0.995 0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.005 0.995 0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.005 0.995 0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.005 0.995 0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.005 0.995 0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.005 0.995 0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.005 0.995 0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.005 0.995 0.000
M11.2 Other chondrocalcinosis
0.005 0.995 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.005 0.995 0.000
M87.2 Osteonecrosis due to previous trauma
0.005 0.995 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.005 0.995 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.005 0.995 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.005 0.995 0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)
0.005 0.995 0.000
M12 Other specific arthropathies
0.005 0.995 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.005 0.995 0.000
M08 Juvenile arthritis
0.005 0.995 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.005 0.995 0.000
M34 Systemic sclerosis
0.005 0.995 0.000
M33 Dermatopolymyositis
0.005 0.995 0.000
M32 Systemic lupus erythematosus
0.005 0.995 0.000
M66.5 Spontaneous rupture of unspecified tendon
0.005 0.995 0.000
M66.4 Spontaneous rupture of other tendons
0.005 0.995 0.000
M66.3 Spontaneous rupture of flexor tendons
0.005 0.995 0.000
M66.1 Rupture of synovium
0.005 0.995 0.000
M66.0 Rupture of popliteal cyst
0.005 0.995 0.000
M89.9 Disorder of bone, unspecified
0.005 0.995 0.000
M24.5 Contracture of joint
0.005 0.995 0.000
M85.9 Disorder of bone density and structure, unspecified
0.005 0.995 0.000
M85.6 Other cyst of bone
0.005 0.995 0.000
M85.5 Aneurysmal bone cyst
0.005 0.995 0.000
M85.4 Solitary bone cyst
0.005 0.995 0.000
M85.3 Osteitis condensans
0.005 0.995 0.000
M85.2 Hyperostosis of skull
0.005 0.995 0.000
M85.1 Skeletal fluorosis
0.005 0.995 0.000
M85.0 Fibrous dysplasia (monostotic)
0.005 0.995 0.000
M05 Seropositive rheumatoid arthritis
0.005 0.995 0.000
M87.8 Other osteonecrosis
0.005 0.995 0.000
M87.3 Other secondary osteonecrosis
0.005 0.995 0.000
M87.1 Osteonecrosis due to drugs
0.005 0.995 0.000
M87.0 Idiopathic aseptic necrosis of bone
0.005 0.995 0.000
M65.84 Other synovitis and tenosynovitis (Hand)
0.005 0.995 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.005 0.995 0.000
M65.14 Other infective (teno)synovitis (Hand)
0.005 0.995 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.005 0.995 0.000
M89.6 Osteopathy after poliomyelitis
0.005 0.995 0.000
M89.5 Osteolysis
0.005 0.995 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.005 0.995 0.000
M89.3 Hypertrophy of bone
0.005 0.995 0.000
M89.2 Other disorders of bone development and growth
0.005 0.995 0.000
M89.1 Epiphyseal arrest
0.005 0.995 0.000
M89.0 Algoneurodystrophy
0.005 0.995 0.000
M92 Other juvenile osteochondrosis
0.005 0.995 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.005 0.995 0.000
M45-M49 Spondylopathies
0.005 0.995 0.000
M81.8 Other osteoporosis
0.005 0.995 0.000
M81.6 Localised osteoporosis [Lequesne]
0.005 0.995 0.000
M81.5 Idiopathic osteoporosis
0.005 0.995 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.005 0.995 0.000
M81.2 Osteoporosis of disuse
0.005 0.995 0.000
M81.1 Postoophorectomy osteoporosis
0.005 0.995 0.000
M81.0 Postmenopausal osteoporosis
0.005 0.995 0.000
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere
0.005 0.995 0.000
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere
0.005 0.995 0.000
M62.88 Other specified disorders of muscle (Other)
0.004 0.995 0.000
M62.87 Other specified disorders of muscle (Ankle and foot)
0.004 0.995 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.004 0.995 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.004 0.995 0.000
M62.84 Other specified disorders of muscle (Hand)
0.004 0.995 0.000
M62.83 Other specified disorders of muscle (Forearm)
0.004 0.995 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.004 0.995 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.004 0.995 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.004 0.995 0.000
M24.2 Disorder of ligament
0.005 0.995 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.005 0.995 0.000
F33 Recurrent depressive disorder
0.005 0.995 0.000
M93 Other osteochondropathies
0.004 0.995 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.005 0.995 0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.005 0.995 0.000
M83.9 Adult osteomalacia, unspecified
0.004 0.995 0.000
M83.8 Other adult osteomalacia
0.004 0.995 0.000
M83.5 Other drug-induced osteomalacia in adults
0.004 0.995 0.000
M83.4 Aluminum bone disease
0.004 0.995 0.000
M83.3 Adult osteomalacia due to malnutrition
0.004 0.995 0.000
M83.2 Adult osteomalacia due to malabsorption
0.004 0.995 0.000
M83.1 Senile osteomalacia
0.004 0.995 0.000
M83.0 Puerperal osteomalacia
0.004 0.995 0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.004 0.995 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.004 0.995 0.000
M96.5 Postradiation scoliosis
0.004 0.995 0.000
M96.4 Postsurgical lordosis
0.004 0.995 0.000
M96.3 Postlaminectomy kyphosis
0.004 0.995 0.000
M96.2 Postradiation kyphosis
0.004 0.995 0.000
M24.1 Other articular cartilage disorders
0.005 0.995 0.000
M07.6 Other enteropathic arthropathies
0.004 0.995 0.000
M07.5 Arthropathy in ulcerative colitis
0.004 0.995 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.004 0.995 0.000
M07.2 Psoriatic spondylitis
0.004 0.995 0.000
M07.1 Arthritis mutilans
0.004 0.995 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.004 0.995 0.000
M22 Disorders of patella
0.004 0.995 0.000
M24.9 Joint derangement, unspecified
0.004 0.995 0.000
M24.7 Protrusio acetabuli
0.004 0.995 0.000
M24.6 Ankylosis of joint
0.004 0.995 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.004 0.995 0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)
0.004 0.995 0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)
0.004 0.995 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.004 0.995 0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.004 0.995 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.004 0.995 0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)
0.004 0.995 0.000
M81.4 Drug-induced osteoporosis
0.004 0.995 0.000
M84.09 Malunion of fracture (Site unspecified)
0.004 0.995 0.000
M84.08 Malunion of fracture (Other)
0.004 0.995 0.000
M84.07 Malunion of fracture (Ankle and foot)
0.004 0.995 0.000
M84.06 Malunion of fracture (Lower leg)
0.004 0.995 0.000
M84.05 Malunion of fracture (Pelvic region and thigh)
0.004 0.995 0.000
M84.04 Malunion of fracture (Hand)
0.004 0.995 0.000
M84.02 Malunion of fracture (Upper arm)
0.004 0.995 0.000
M84.01 Malunion of fracture (Shoulder region)
0.004 0.995 0.000
M84.00 Malunion of fracture (Multiple sites)
0.004 0.995 0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.004 0.995 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.004 0.995 0.000
M94 Other disorders of cartilage
0.004 0.996 0.000
M21.2 Flexion deformity
0.004 0.996 0.000
M89.86 Other specified disorders of bone (Lower leg)
0.004 0.996 0.000
M24.0 Loose body in joint
0.004 0.996 0.000
M80.8 Other osteoporosis with pathological fracture
0.004 0.996 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.004 0.996 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.004 0.996 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.004 0.996 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.004 0.996 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.004 0.996 0.000
M06 Other rheumatoid arthritis
0.004 0.996 0.000
M43.0 Spondylolysis
0.004 0.996 0.000
M60.9 Myositis, unspecified
0.004 0.996 0.000
M60.8 Other myositis
0.004 0.996 0.000
M60.2 Foreign body granuloma of soft tissue, not elsewhere classified
0.004 0.996 0.000
M60.1 Interstitial myositis
0.004 0.996 0.000
M60.0 Infective myositis
0.004 0.996 0.000
M61.9 Calcification and ossification of muscle, unspecified
0.004 0.996 0.000
M61.5 Other ossification of muscle
0.004 0.996 0.000
M61.4 Other calcification of muscle
0.004 0.996 0.000
M61.3 Calcification and ossification of muscles associated with burns
0.004 0.996 0.000
M61.2 Paralytic calcification and ossification of muscle
0.004 0.996 0.000
M61.1 Myositis ossificans progressiva
0.004 0.996 0.000
M61.0 Myositis ossificans traumatica
0.004 0.996 0.000
M63.8 Other disorders of muscle in diseases classified elsewhere
0.004 0.996 0.000
M63.3 Myositis in sarcoidosis
0.004 0.996 0.000
M63.2 Myositis in other infectious diseases classified elsewhere
0.004 0.996 0.000
M63.1 Myositis in protozoal and parasitic infections classified elsewhere
0.004 0.996 0.000
M63.0 Myositis in bacterial diseases classified elsewhere
0.004 0.996 0.000
M90.8 Osteopathy in other diseases classified elsewhere
0.004 0.996 0.000
M90.7 Fracture of bone in neoplastic disease
0.004 0.996 0.000
M90.6 Osteitis deformans in neoplastic disease
0.004 0.996 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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