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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12529935
log Bayes Factor = 1.93745
Chromosome 6   position 91,015,039  (GRCh37) Explore rs12529935 on Ensembl!
Variant rs12529935 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10 Insulin-dependent diabetes mellitus
0.000 0.016 0.984
E10.3 With ophthalmic complications
0.000 0.018 0.982
E10-E14 Diabetes mellitus
0.000 0.031 0.969
E10.9 Without complications
0.000 0.040 0.960
E03.9 Hypothyroidism, unspecified
0.000 0.050 0.950
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.050 0.950
E03 Other hypothyroidism
0.000 0.056 0.944
E00-E07 Disorders of thyroid gland
0.000 0.061 0.939
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.070 0.930
E16 Other disorders of pancreatic internal secretion
0.000 0.084 0.916
E16.2 Hypoglycaemia, unspecified
0.000 0.091 0.909
E10.4 With neurological complications
0.000 0.098 0.902
E11 Non-insulin-dependent diabetes mellitus
0.000 0.112 0.888
E10.1 With ketoacidosis
0.000 0.121 0.879
E11.3 With ophthalmic complications
0.000 0.179 0.821
E11.5 With peripheral circulatory complications
0.000 0.224 0.776
E50-E64 Other nutritional deficiencies
0.000 0.251 0.749
E03.8 Other specified hypothyroidism
0.000 0.269 0.731
E11.2 With renal complications
0.000 0.270 0.730
E11.8 With unspecified complications
0.000 0.273 0.727
E10.7 With multiple complications
0.000 0.294 0.705
E10.6 With other specified complications
0.000 0.294 0.705
E11.0 With coma
0.000 0.302 0.698
E12 Malnutrition-related diabetes mellitus
0.000 0.305 0.694
E03.5 Myxoedema coma
0.000 0.323 0.676
E03.4 Atrophy of thyroid (acquired)
0.000 0.323 0.676
E03.3 Postinfectious hypothyroidism
0.000 0.323 0.676
E03.1 Congenital hypothyroidism without goitre
0.000 0.323 0.676
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.323 0.676
E06 Thyroiditis
0.000 0.324 0.676
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.326 0.673
E00 Congenital iodine-deficiency syndrome
0.000 0.326 0.673
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.326 0.673
E40-E46 Malnutrition
0.000 0.327 0.673
E13 Other specified diabetes mellitus
0.000 0.333 0.667
E15 Nondiabetic hypoglycaemic coma
0.000 0.333 0.667
E10.0 With coma
0.000 0.335 0.665
E10.2 With renal complications
0.000 0.338 0.662
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.343 0.657
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.343 0.657
E16.4 Abnormal secretion of gastrin
0.000 0.343 0.657
E16.3 Increased secretion of glucagon
0.000 0.343 0.657
E20-E35 Disorders of other endocrine glands
0.000 0.345 0.655
E10.8 With unspecified complications
0.000 0.349 0.651
E10.5 With peripheral circulatory complications
0.000 0.360 0.640
E11.7 With multiple complications
0.000 0.363 0.636
E16.1 Other hypoglycaemia
0.000 0.369 0.631
E11.6 With other specified complications
0.000 0.370 0.630
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.396 0.604
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.411 0.589
E61 Deficiency of other nutrient elements
0.000 0.411 0.588
E11.1 With ketoacidosis
0.000 0.428 0.572
E53 Deficiency of other B group vitamins
0.000 0.432 0.568
E22 Hyperfunction of pituitary gland
0.000 0.450 0.550
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.463 0.537
E63 Other nutritional deficiencies
0.000 0.463 0.537
E56 Other vitamin deficiencies
0.000 0.463 0.537
E51 Thiamine deficiency
0.000 0.463 0.537
E50 Vitamin A deficiency
0.000 0.463 0.537
E60 Dietary zinc deficiency
0.000 0.463 0.537
E59 Dietary selenium deficiency
0.000 0.463 0.537
E58 Dietary calcium deficiency
0.000 0.463 0.537
E54 Ascorbic acid deficiency
0.000 0.463 0.537
E52 Niacin deficiency [pellagra]
0.000 0.463 0.537
E06.3 Autoimmune thyroiditis
0.000 0.471 0.529
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.474 0.526
E55 Vitamin D deficiency
0.000 0.475 0.525
E65-E68 Obesity and other hyperalimentation
0.000 0.481 0.519
E11.4 With neurological complications
0.000 0.481 0.519
E28 Ovarian dysfunction
0.000 0.492 0.508
E12.9 Without complications
0.000 0.502 0.498
E12.8 With unspecified complications
0.000 0.502 0.498
E12.7 With multiple complications
0.000 0.502 0.498
E12.6 With other specified complications
0.000 0.502 0.498
E12.5 With peripheral circulatory complications
0.000 0.502 0.498
E12.4 With neurological complications
0.000 0.502 0.498
E12.3 With ophthalmic complications
0.000 0.502 0.498
E12.2 With renal complications
0.000 0.502 0.498
E12.1 With ketoacidosis
0.000 0.502 0.498
E12.0 With coma
0.000 0.502 0.498
E34 Other endocrine disorders
0.000 0.508 0.492
E26 Hyperaldosteronism
0.000 0.510 0.490
E06.5 Other chronic thyroiditis
0.000 0.515 0.485
E06.4 Drug-induced thyroiditis
0.000 0.515 0.485
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.515 0.485
E06.1 Subacute thyroiditis
0.000 0.515 0.485
E06.0 Acute thyroiditis
0.000 0.515 0.485
E20 Hypoparathyroidism
0.000 0.516 0.484
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.517 0.483
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.517 0.483
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.517 0.483
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.517 0.483
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.517 0.483
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.517 0.483
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.517 0.483
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.517 0.483
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.517 0.483
E45 Retarded development following protein-energy malnutrition
0.000 0.517 0.483
E43 Unspecified severe protein-energy malnutrition
0.000 0.517 0.483
E42 Marasmic kwashiorkor
0.000 0.517 0.483
E41 Nutritional marasmus
0.000 0.517 0.483
E40 Kwashiorkor
0.000 0.517 0.483
E13.8 With unspecified complications
0.000 0.522 0.478
E13.7 With multiple complications
0.000 0.522 0.478
E13.6 With other specified complications
0.000 0.522 0.478
E13.5 With peripheral circulatory complications
0.000 0.522 0.478
E13.4 With neurological complications
0.000 0.522 0.478
E13.3 With ophthalmic complications
0.000 0.522 0.478
E13.2 With renal complications
0.000 0.522 0.478
E13.1 With ketoacidosis
0.000 0.522 0.478
E13.0 With coma
0.000 0.522 0.478
E14 Unspecified diabetes mellitus
0.000 0.523 0.477
E46 Unspecified protein-energy malnutrition
0.000 0.525 0.475
E61.1 Iron deficiency
0.000 0.526 0.474
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.530 0.470
E32 Diseases of thymus
0.000 0.530 0.470
E31 Polyglandular dysfunction
0.000 0.530 0.470
E30 Disorders of puberty, not elsewhere classified
0.000 0.530 0.470
E25 Adrenogenital disorders
0.000 0.530 0.470
E22.0 Acromegaly and pituitary gigantism
0.000 0.543 0.457
E13.9 Without complications
0.000 0.549 0.451
E21.3 Hyperparathyroidism, unspecified
0.000 0.554 0.446
E29 Testicular dysfunction
0.000 0.556 0.444
E53.8 Deficiency of other specified B group vitamins
0.000 0.562 0.438
E06.9 Thyroiditis, unspecified
0.000 0.568 0.431
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.577 0.423
E61.9 Deficiency of nutrient element, unspecified
0.000 0.578 0.422
E61.8 Deficiency of other specified nutrient elements
0.000 0.578 0.422
E61.7 Deficiency of multiple nutrient elements
0.000 0.578 0.422
E61.6 Vanadium deficiency
0.000 0.578 0.422
E61.5 Molybdenum deficiency
0.000 0.578 0.422
E61.4 Chromium deficiency
0.000 0.578 0.422
E61.3 Manganese deficiency
0.000 0.578 0.422
E61.2 Magnesium deficiency
0.000 0.578 0.422
E61.0 Copper deficiency
0.000 0.578 0.422
E53.9 Vitamin B deficiency, unspecified
0.000 0.593 0.407
E53.1 Pyridoxine deficiency
0.000 0.593 0.407
E53.0 Riboflavin deficiency
0.000 0.593 0.407
E34.9 Endocrine disorder, unspecified
0.000 0.593 0.407
E28.2 Polycystic ovarian syndrome
0.000 0.598 0.402
E23 Hypofunction and other disorders of pituitary gland
0.000 0.601 0.399
E22.1 Hyperprolactinaemia
0.000 0.603 0.397
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.603 0.397
E65 Localised adiposity
0.000 0.605 0.395
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.605 0.395
E22.8 Other hyperfunction of pituitary gland
0.000 0.605 0.395
E50.9 Vitamin A deficiency, unspecified
0.000 0.615 0.385
E50.8 Other manifestations of vitamin A deficiency
0.000 0.615 0.385
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.615 0.385
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.615 0.385
E50.5 Vitamin A deficiency with night blindness
0.000 0.615 0.385
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.615 0.385
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.615 0.385
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.615 0.385
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.615 0.385
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.615 0.385
E51.9 Thiamine deficiency, unspecified
0.000 0.615 0.385
E51.8 Other manifestations of thiamine deficiency
0.000 0.615 0.385
E51.2 Wernicke's encephalopathy
0.000 0.615 0.385
E51.1 Beriberi
0.000 0.615 0.385
E56.9 Vitamin deficiency, unspecified
0.000 0.615 0.385
E56.8 Deficiency of other vitamins
0.000 0.615 0.385
E56.1 Deficiency of vitamin K
0.000 0.615 0.385
E56.0 Deficiency of vitamin E
0.000 0.615 0.385
E63.9 Nutritional deficiency, unspecified
0.000 0.615 0.385
E63.8 Other specified nutritional deficiencies
0.000 0.615 0.385
E63.1 Imbalance of constituents of food intake
0.000 0.615 0.385
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.615 0.385
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.615 0.385
E64.8 Sequelae of other nutritional deficiencies
0.000 0.615 0.385
E64.3 Sequelae of rickets
0.000 0.615 0.385
E64.2 Sequelae of vitamin C deficiency
0.000 0.615 0.385
E64.1 Sequelae of vitamin A deficiency
0.000 0.615 0.385
E64.0 Sequelae of protein-energy malnutrition
0.000 0.615 0.385
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.623 0.377
E21.4 Other specified disorders of parathyroid gland
0.000 0.623 0.377
E21.2 Other hyperparathyroidism
0.000 0.623 0.377
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.623 0.377
E55.0 Rickets, active
0.000 0.623 0.377
E67 Other hyperalimentation
0.000 0.627 0.372
E68 Sequelae of hyperalimentation
0.000 0.627 0.372
E07 Other disorders of thyroid
0.001 0.628 0.372
E26.0 Primary hyperaldosteronism
0.000 0.628 0.372
E55.9 Vitamin D deficiency, unspecified
0.000 0.635 0.365
E28.9 Ovarian dysfunction, unspecified
0.000 0.636 0.364
E28.8 Other ovarian dysfunction
0.000 0.636 0.364
E28.3 Primary ovarian failure
0.000 0.636 0.364
E28.1 Androgen excess
0.000 0.636 0.364
E28.0 Oestrogen excess
0.000 0.636 0.364
E20.9 Hypoparathyroidism, unspecified
0.000 0.638 0.362
E34.0 Carcinoid syndrome
0.000 0.641 0.359
E21.0 Primary hyperparathyroidism
0.000 0.647 0.353
E34.5 Androgen resistance syndrome
0.000 0.647 0.353
E34.4 Constitutional tall stature
0.000 0.647 0.353
E34.3 Short stature, not elsewhere classified
0.000 0.647 0.353
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.647 0.353
E34.1 Other hypersecretion of intestinal hormones
0.000 0.647 0.353
E26.9 Hyperaldosteronism, unspecified
0.000 0.648 0.351
E26.8 Other hyperaldosteronism
0.000 0.648 0.351
E26.1 Secondary hyperaldosteronism
0.000 0.648 0.351
E20.8 Other hypoparathyroidism
0.000 0.653 0.347
E20.1 Pseudohypoparathyroidism
0.000 0.653 0.347
E20.0 Idiopathic hypoparathyroidism
0.000 0.653 0.347
E44.1 Mild protein-energy malnutrition
0.000 0.654 0.346
E44.0 Moderate protein-energy malnutrition
0.000 0.654 0.346
E24 Cushing's syndrome
0.000 0.655 0.344
E14.8 With unspecified complications
0.000 0.657 0.342
E14.7 With multiple complications
0.000 0.657 0.342
E14.6 With other specified complications
0.000 0.657 0.342
E14.5 With peripheral circulatory complications
0.000 0.657 0.342
E14.4 With neurological complications
0.000 0.657 0.342
E14.2 Withrenal complications
0.000 0.657 0.342
E14.1 With ketoacidosis
0.000 0.657 0.342
E14.0 With coma
0.000 0.657 0.342
E25.9 Adrenogenital disorder, unspecified
0.000 0.663 0.337
E25.8 Other adrenogenital disorders
0.000 0.663 0.337
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.663 0.337
E30.9 Disorder of puberty, unspecified
0.000 0.663 0.337
E30.8 Other disorders of puberty
0.000 0.663 0.337
E30.1 Precocious puberty
0.000 0.663 0.337
E30.0 Delayed puberty
0.000 0.663 0.337
E31.9 Polyglandular dysfunction, unspecified
0.000 0.663 0.337
E31.8 Other polyglandular dysfunction
0.000 0.663 0.337
E31.1 Polyglandular hyperfunction
0.000 0.663 0.337
E31.0 Autoimmune polyglandular failure
0.000 0.663 0.337
E32.9 Disease of thymus, unspecified
0.000 0.663 0.337
E32.8 Other diseases of thymus
0.000 0.663 0.337
E32.1 Abscess of thymus
0.000 0.663 0.337
E32.0 Persistent hyperplasia of thymus
0.000 0.663 0.337
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.663 0.337
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.663 0.337
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.663 0.337
E14.3 With ophthalmic complications
0.000 0.665 0.335
E29.9 Testicular dysfunction, unspecified
0.000 0.682 0.318
E29.8 Other testicular dysfunction
0.000 0.682 0.318
E29.0 Testicular hyperfunction
0.000 0.682 0.318
E27 Other disorders of adrenal gland
0.000 0.701 0.298
E23.2 Diabetes insipidus
0.000 0.705 0.295
E34.8 Other specified endocrine disorders
0.000 0.706 0.294
E29.1 Testicular hypofunction
0.000 0.707 0.292
E23.6 Other disorders of pituitary gland
0.000 0.713 0.286
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.713 0.286
E23.1 Drug-induced hypopituitarism
0.000 0.713 0.286
E05.8 Other thyrotoxicosis
0.000 0.715 0.284
E05.5 Thyroid crisis or storm
0.000 0.715 0.284
E05.4 Thyrotoxicosis factitia
0.000 0.715 0.284
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.715 0.284
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.715 0.284
E23.7 Disorder of pituitary gland, unspecified
0.000 0.726 0.274
E67.8 Other specified hyperalimentation
0.000 0.733 0.267
E67.3 Hypervitaminosis D
0.000 0.733 0.267
E67.2 Megavitamin-B6 syndrome
0.000 0.733 0.267
E67.1 Hypercarotenaemia
0.000 0.733 0.267
E67.0 Hypervitaminosis A
0.000 0.733 0.267
E07.1 Dyshormogenetic goitre
0.001 0.733 0.266
E07.0 Hypersecretion of calcitonin
0.001 0.733 0.266
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.751 0.249
E24.8 Other Cushing's syndrome
0.000 0.753 0.247
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.753 0.247
E24.3 Ectopic ACTH syndrome
0.000 0.753 0.247
E24.1 Nelson's syndrome
0.000 0.753 0.247
E27.8 Other specified disorders of adrenal gland
0.000 0.773 0.227
E23.0 Hypopituitarism
0.000 0.780 0.220
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.780 0.220
E24.9 Cushing's syndrome, unspecified
0.000 0.781 0.218
E24.2 Drug-induced Cushing's syndrome
0.001 0.783 0.216
E27.5 Adrenomedullary hyperfunction
0.000 0.786 0.214
E27.2 Addisonian crisis
0.000 0.786 0.214
E27.0 Other adrenocortical overactivity
0.000 0.786 0.214
E24.0 Pituitary-dependent Cushing's disease
0.001 0.787 0.213
E27.9 Disorder of adrenal gland, unspecified
0.000 0.790 0.210
E05.9 Thyrotoxicosis, unspecified
0.000 0.791 0.209
E04 Other non-toxic goitre
0.000 0.797 0.203
E07.8 Other specified disorders of thyroid
0.001 0.807 0.192
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.823 0.177
E27.1 Primary adrenocortical insufficiency
0.000 0.827 0.173
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.837 0.163
J33.9 Nasal polyp, unspecified
0.157 0.843 0.000
E66 Obesity
0.000 0.844 0.156
J33 Nasal polyp
0.155 0.845 0.000
J33.8 Other polyp of sinus
0.152 0.848 0.000
J33.0 Polyp of nasal cavity
0.148 0.852 0.000
E04.8 Other specified non-toxic goitre
0.000 0.854 0.145
E04.1 Non-toxic single thyroid nodule
0.000 0.855 0.145
E14.9 Without complications
0.000 0.857 0.143
E07.9 Disorder of thyroid, unspecified
0.001 0.866 0.133
E04.0 Non-toxic diffuse goitre
0.000 0.876 0.124
E66.1 Drug-induced obesity
0.000 0.888 0.112
J33.1 Polypoid sinus degeneration
0.111 0.889 0.000
E66.8 Other obesity
0.000 0.889 0.111
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.894 0.106
E66.0 Obesity due to excess calories
0.000 0.914 0.085
E04.9 Non-toxic goitre, unspecified
0.000 0.936 0.064
E04.2 Non-toxic multinodular goitre
0.001 0.954 0.046
E70-E90 Metabolic disorders
0.000 0.979 0.021
E11.9 Without complications
0.000 0.980 0.020
E84 Cystic fibrosis
0.000 0.984 0.015
E79 Disorders of purine and pyrimidine metabolism
0.000 0.984 0.015
E77 Disorders of glycoprotein metabolism
0.000 0.984 0.015
E76 Disorders of glycosaminoglycan metabolism
0.000 0.984 0.015
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.984 0.015
E72 Other disorders of amino-acid metabolism
0.000 0.984 0.015
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.984 0.015
E70 Disorders of aromatic amino-acid metabolism
0.000 0.984 0.015
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.984 0.015
E88 Other metabolic disorders
0.000 0.985 0.015
E73 Lactose intolerance
0.000 0.985 0.014
E74 Other disorders of carbohydrate metabolism
0.000 0.986 0.014
E66.9 Obesity, unspecified
0.000 0.986 0.014
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.986 0.014
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.987 0.013
E86 Volume depletion
0.000 0.988 0.012
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.989 0.011
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.989 0.011
E70.3 Albinism
0.000 0.989 0.011
E70.2 Disorders of tyrosine metabolism
0.000 0.989 0.011
E70.1 Other hyperphenylalaninaemias
0.000 0.989 0.011
E70.0 Classical phenylketonuria
0.000 0.989 0.011
E71.3 Disorders of fatty-acid metabolism
0.000 0.989 0.011
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.989 0.011
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.989 0.011
E71.0 Maple-syrup-urine disease
0.000 0.989 0.011
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.989 0.011
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.989 0.011
E72.5 Disorders of glycine metabolism
0.000 0.989 0.011
E72.4 Disorders of ornithine metabolism
0.000 0.989 0.011
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.989 0.011
E72.2 Disorders of urea cycle metabolism
0.000 0.989 0.011
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.989 0.011
E72.0 Disorders of amino-acid transport
0.000 0.989 0.011
E75.6 Lipid storage disorder, unspecified
0.000 0.989 0.011
E75.5 Other lipid storage disorders
0.000 0.989 0.011
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.989 0.011
E75.3 Sphingolipidosis, unspecified
0.000 0.989 0.011
E75.2 Other sphingolipidosis
0.000 0.989 0.011
E75.1 Other gangliosidosis
0.000 0.989 0.011
E75.0 GM2 gangliosidosis
0.000 0.989 0.011
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.989 0.011
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.989 0.011
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.989 0.011
E76.2 Other mucopolysaccharidoses
0.000 0.989 0.011
E76.1 Mucopolysaccharidosis, type II
0.000 0.989 0.011
E76.0 Mucopolysaccharidosis, type I
0.000 0.989 0.011
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.989 0.011
E77.8 Other disorders of glycoprotein metabolism
0.000 0.989 0.011
E77.1 Defects in glycoprotein degradation
0.000 0.989 0.011
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.989 0.011
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.989 0.011
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.989 0.011
E79.1 Lesch-Nyhan syndrome
0.000 0.989 0.011
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.989 0.011
E84.9 Cystic fibrosis, unspecified
0.000 0.989 0.011
E84.8 Cystic fibrosis with other manifestations
0.000 0.989 0.011
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.989 0.011
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.989 0.011
E88.9 Metabolic disorder, unspecified
0.000 0.989 0.011
E88.8 Other specified metabolic disorders
0.000 0.989 0.011
E88.3 Tumour lysis syndrome
0.000 0.989 0.011
E88.2 Lipomatosis, not elsewhere classified
0.000 0.989 0.011
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.989 0.011
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.989 0.011
E89.2 Postprocedural hypoparathyroidism
0.000 0.989 0.011
E73.8 Other lactose intolerance
0.000 0.989 0.010
E73.1 Secondary lactase deficiency
0.000 0.989 0.010
E73.0 Congenital lactase deficiency
0.000 0.989 0.010
E89.3 Postprocedural hypopituitarism
0.000 0.989 0.011
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.989 0.010
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.989 0.010
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.989 0.010
E74.2 Disorders of galactose metabolism
0.000 0.989 0.010
E74.1 Disorders of fructose metabolism
0.000 0.989 0.010
E74.0 Glycogen storage disease
0.000 0.989 0.010
E83 Disorders of mineral metabolism
0.000 0.990 0.010
E85 Amyloidosis
0.000 0.990 0.010
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.990 0.010
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.990 0.010
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.990 0.010
E89.5 Postprocedural testicular hypofunction
0.000 0.990 0.010
E89.4 Postprocedural ovarian failure
0.000 0.990 0.010
E89.1 Postprocedural hypoinsulinaemia
0.000 0.990 0.010
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.990 0.010
E80.6 Other disorders of bilirubin metabolism
0.000 0.990 0.010
E80.5 Crigler-Najjar syndrome
0.000 0.990 0.010
E80.3 Defects of catalase and peroxydase
0.000 0.990 0.010
E80.2 Other porphyria
0.000 0.990 0.010
E80.1 Porphyria cutanea tarda
0.000 0.990 0.010
E80.0 Hereditary erythropoietic porphyria
0.000 0.990 0.010
H36.0 Diabetic retinopathy
0.000 0.990 0.010
E73.9 Lactose intolerance, unspecified
0.000 0.990 0.009
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.991 0.009
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.009 0.991 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.009 0.991 0.000
E83.1 Disorders of iron metabolism
0.000 0.992 0.008
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.008 0.992 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.008 0.992 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.008 0.992 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.992 0.008
E83.8 Other disorders of mineral metabolism
0.000 0.992 0.008
E83.2 Disorders of zinc metabolism
0.000 0.992 0.008
E83.0 Disorders of copper metabolism
0.000 0.992 0.008
O36.8 Maternal care for other specified foetal problems
0.008 0.992 0.000
K62.0 Anal polyp
0.008 0.992 0.000
E80.4 Gilbert's syndrome
0.000 0.992 0.007
E85.8 Other amyloidosis
0.000 0.992 0.007
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.992 0.007
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.992 0.007
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.992 0.007
I84.9 Unspecified haemorrhoids without complication
0.007 0.993 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.007 0.993 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.007 0.993 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.007 0.993 0.000
E83.4 Disorders of magnesium metabolism
0.000 0.993 0.007
E85.9 Amyloidosis, unspecified
0.000 0.993 0.006
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.007 0.993 0.000
N43.3 Hydrocele, unspecified
0.007 0.993 0.000
E85.3 Secondary systemic amyloidosis
0.001 0.994 0.006
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.994 0.006
E83.5 Disorders of calcium metabolism
0.000 0.994 0.006
H36 Retinal disorders in diseases classified elsewhere
0.000 0.994 0.006
E85.4 Organ-limited amyloidosis
0.001 0.994 0.006
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.006 0.994 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.006 0.994 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.994 0.006
O34 Maternal care for known or suspected abnormality of pelvic organs
0.006 0.994 0.000
O36 Maternal care for other known or suspected foetal problems
0.006 0.994 0.000
E78.1 Pure hyperglyceridaemia
0.000 0.995 0.005
O36.4 Maternal care for intra-uterine death
0.005 0.995 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.005 0.995 0.000
E89.0 Postprocedural hypothyroidism
0.000 0.995 0.005
K04.7 Periapical abscess without sinus
0.005 0.995 0.000
S80.0 Contusion of knee
0.005 0.995 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.005 0.995 0.000
O34.3 Maternal care for cervical incompetence
0.005 0.995 0.000
E78.6 Lipoprotein deficiency
0.000 0.995 0.005
E78.3 Hyperchylomicronaemia
0.000 0.995 0.005
E78.2 Mixed hyperlipidaemia
0.000 0.995 0.005
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.995 0.005
E83.3 Disorders of phosphorus metabolism
0.000 0.995 0.004
S06.20 Diffuse brain injury (without open intracranial wound)
0.005 0.995 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.004 0.995 0.000
O34.1 Maternal care for tumour of corpus uteri
0.004 0.995 0.000
C54.1 Endometrium
0.005 0.995 0.000
E78.8 Other disorders of lipoprotein metabolism
0.000 0.996 0.004
O34.8 Maternal care for other abnormalities of pelvic organs
0.004 0.996 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.004 0.996 0.000
O34.6 Maternal care for abnormality of vagina
0.004 0.996 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.004 0.996 0.000
O34.0 Maternal care for congenital malformation of uterus
0.004 0.996 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.004 0.996 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.004 0.996 0.000
O23 Infections of genito-urinary tract in pregnancy
0.004 0.996 0.000
E78.4 Other hyperlipidaemia
0.000 0.996 0.004
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.004 0.996 0.000
O36.2 Maternal care for hydrops foetalis
0.004 0.996 0.000
O36.1 Maternal care for other isoimmunisation
0.004 0.996 0.000
R94.5 Abnormal results of liver function studies
0.004 0.996 0.000
O36.5 Maternal care for poor foetal growth
0.004 0.996 0.000
H52.1 Myopia
0.004 0.996 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.004 0.996 0.000
O97 Death from sequelae of direct obstetric causes
0.004 0.996 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.004 0.996 0.000
O95 Obstetric death of unspecified cause
0.004 0.996 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.004 0.996 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.004 0.996 0.000
N41.1 Chronic prostatitis
0.004 0.996 0.000
O34.4 Maternal care for other abnormalities of cervix
0.004 0.996 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.004 0.996 0.000
H34 Retinal vascular occlusions
0.000 0.996 0.004
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.004 0.996 0.000
N43 Hydrocele and spermatocele
0.004 0.996 0.000
O26.2 Pregnancy care of habitual aborter
0.004 0.996 0.000
O36.9 Maternal care for foetal problem, unspecified
0.004 0.996 0.000
O23.5 Infections of the genital tract in pregnancy
0.004 0.996 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.004 0.996 0.000
H34.2 Other retinal artery occlusions
0.000 0.996 0.004
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.996 0.004
O32.4 Maternal care for high head at term
0.004 0.996 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.996 0.004
O32.8 Maternal care for other malpresentation of foetus
0.003 0.996 0.000
H34.8 Other retinal vascular occlusions
0.000 0.996 0.004
O20-O29 Other maternal disorders predominantly related to pregnancy
0.004 0.996 0.000
H30-H36 Disorders of choroid and retina
0.000 0.997 0.003
K65.9 Peritonitis, unspecified
0.003 0.997 0.000
O36.6 Maternal care for excessive foetal growth
0.003 0.997 0.000
H52.3 Anisometropia and aniseikonia
0.003 0.997 0.000
S80 Superficial injury of lower leg
0.003 0.997 0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy
0.003 0.997 0.000
O23.3 Infections of other parts of urinary tract in pregnancy
0.003 0.997 0.000
O23.2 Infections of urethra in pregnancy
0.003 0.997 0.000
O23.1 Infections of bladder in pregnancy
0.003 0.997 0.000
O23.0 Infections of kidney in pregnancy
0.003 0.997 0.000
H35.5 Hereditary retinal dystrophy
0.000 0.997 0.003
N36.8 Other specified disorders of urethra
0.003 0.997 0.000
H52 Disorders of refraction and accommodation
0.003 0.997 0.000
H35 Other retinal disorders
0.000 0.997 0.003
O96.9 Death from unspecified obstetric cause
0.003 0.997 0.000
O96.1 Death from indirect obstetric cause
0.003 0.997 0.000
O96.0 Death from direct obstetric cause
0.003 0.997 0.000
O97.9 Death from sequelae of obstetric cause, unspecified
0.003 0.997 0.000
O97.1 Death from sequelae of indirect obstetric cause
0.003 0.997 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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