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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12530
log Bayes Factor = 0.291577
Chromosome 22   position 32,783,904  (GRCh37) Explore rs12530 on Ensembl!
Variant rs12530 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K76 Other diseases of liver
0.000 0.550 0.450
K76.6 Portal hypertension
0.000 0.550 0.450
K74 Fibrosis and cirrhosis of liver
0.000 0.555 0.445
K70-K77 Diseases of liver
0.000 0.555 0.445
K74.6 Other and unspecified cirrhosis of liver
0.000 0.561 0.439
K76.9 Liver disease, unspecified
0.000 0.572 0.428
K74.3 Primary biliary cirrhosis
0.000 0.621 0.379
K70 Alcoholic liver disease
0.000 0.632 0.368
K72 Hepatic failure, not elsewhere classified
0.000 0.633 0.367
K74.5 Biliary cirrhosis, unspecified
0.000 0.636 0.364
K73 Chronic hepatitis, not elsewhere classified
0.000 0.657 0.343
K76.8 Other specified diseases of liver
0.000 0.667 0.333
K70.3 Alcoholic cirrhosis of liver
0.000 0.667 0.333
K74.0 Hepatic fibrosis
0.000 0.670 0.330
K75 Other inflammatory liver diseases
0.000 0.672 0.328
K76.5 Hepatic veno-occlusive disease
0.000 0.677 0.323
K76.4 Peliosis hepatis
0.000 0.677 0.323
K76.3 Infarction of liver
0.000 0.677 0.323
K76.2 Central haemorrhagic necrosis of liver
0.000 0.677 0.323
K76.1 Chronic passive congestion of liver
0.000 0.677 0.323
K74.4 Secondary biliary cirrhosis
0.000 0.680 0.319
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.680 0.319
K74.1 Hepatic sclerosis
0.000 0.680 0.319
K77 Liver disorders in diseases classified elsewhere
0.000 0.680 0.319
K72.9 Hepatic failure, unspecified
0.000 0.693 0.307
K70.0 Alcoholic fatty liver
0.000 0.693 0.307
K71 Toxic liver disease
0.000 0.714 0.286
K73.9 Chronic hepatitis, unspecified
0.000 0.714 0.286
K76.7 Hepatorenal syndrome
0.000 0.724 0.276
K72.0 Acute and subacute hepatic failure
0.000 0.730 0.270
K75.4 Autoimmune hepatitis
0.000 0.733 0.267
K75.8 Other specified inflammatory liver diseases
0.000 0.734 0.266
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.736 0.264
K72.1 Chronic hepatic failure
0.000 0.737 0.263
K70.1 Alcoholic hepatitis
0.000 0.750 0.250
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.754 0.246
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.754 0.246
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.754 0.246
K75.2 Nonspecific reactive hepatitis
0.000 0.764 0.236
K75.1 Phlebitis of portal vein
0.000 0.764 0.236
K76.0 Fatty (change of) liver, not elsewhere classified
0.000 0.770 0.230
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.771 0.229
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.771 0.229
K75.9 Inflammatory liver disease, unspecified
0.000 0.773 0.227
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.781 0.219
K70.9 Alcoholic liver disease, unspecified
0.000 0.786 0.214
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.791 0.209
K71.9 Toxic liver disease, unspecified
0.000 0.795 0.205
K71.8 Toxic liver disease with other disorders of liver
0.000 0.795 0.205
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.795 0.205
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.795 0.205
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.795 0.205
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.795 0.205
K71.2 Toxic liver disease with acute hepatitis
0.000 0.795 0.205
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.795 0.205
K70.4 Alcoholic hepatic failure
0.000 0.803 0.197
K75.0 Abscess of liver
0.000 0.805 0.195
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.806 0.194
K71.0 Toxic liver disease with cholestasis
0.000 0.814 0.185
K59.0 Constipation
0.149 0.851 0.000
D68.2 Hereditary deficiency of other clotting factors
0.048 0.952 0.000
D68 Other coagulation defects
0.047 0.953 0.000
D68.8 Other specified coagulation defects
0.044 0.956 0.000
D68.9 Coagulation defect, unspecified
0.043 0.957 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.043 0.957 0.000
D68.6 Other Thrombophilia
0.037 0.963 0.000
D68.1 Hereditary factor XI deficiency
0.036 0.964 0.000
D68.4 Acquired coagulation factor deficiency
0.035 0.965 0.000
D68.5 Primary Thrombophilia
0.027 0.973 0.000
K83.1 Obstruction of bile duct
0.000 0.974 0.026
D68.0 Von Willebrand's disease
0.026 0.974 0.000
K59 Other functional intestinal disorders
0.022 0.978 0.000
K59.3 Megacolon, not elsewhere classified
0.019 0.981 0.000
K59.2 Neurogenic bowel, not elsewhere classified
0.018 0.982 0.000
T43.2 Other and unspecified antidepressants
0.018 0.982 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.016 0.984 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.016 0.984 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.014 0.986 0.000
D66 Hereditary factor VIII deficiency
0.013 0.987 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.013 0.987 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.012 0.988 0.000
K59.8 Other specified functional intestinal disorders
0.012 0.988 0.000
D67 Hereditary factor IX deficiency
0.012 0.988 0.000
T43.6 Psychostimulants with abuse potential
0.012 0.988 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.012 0.988 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.011 0.988 0.000
K55.0 Acute vascular disorders of intestine
0.011 0.989 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.011 0.989 0.000
K59.4 Anal spasm
0.011 0.989 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.011 0.989 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.011 0.989 0.000
K59.1 Functional diarrhoea
0.011 0.989 0.000
T43.9 Psychotropic drug, unspecified
0.010 0.990 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.010 0.990 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.010 0.990 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.010 0.990 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.010 0.990 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.010 0.990 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.010 0.990 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.010 0.990 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.010 0.990 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.009 0.991 0.000
T82.1 Mechanical complication of cardiac electronic device
0.009 0.991 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.009 0.991 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.009 0.991 0.000
K59.9 Functional intestinal disorder, unspecified
0.008 0.991 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.009 0.991 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.008 0.991 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.008 0.991 0.000
D22.5 Melanocytic naevi of trunk
0.000 0.992 0.008
T47.0 Histamine H(2)-receptor antagonists
0.008 0.992 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.008 0.992 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.008 0.992 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.008 0.992 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.008 0.992 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.008 0.992 0.000
T36 Poisoning by systemic antibiotics
0.008 0.992 0.000
T39.1 4-Aminophenol derivatives
0.008 0.992 0.000
T39.0 Salicylates
0.008 0.992 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.008 0.992 0.000
G30.9 Alzheimer's disease, unspecified
0.000 0.992 0.008
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.007 0.993 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.007 0.993 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.007 0.993 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.007 0.993 0.000
T47.7 Emetics
0.007 0.993 0.000
T47.6 Antidiarrhoeal drugs
0.007 0.993 0.000
T47.5 Digestants
0.007 0.993 0.000
T47.4 Other laxatives
0.007 0.993 0.000
T47.3 Saline and osmotic laxatives
0.007 0.993 0.000
T47.2 Stimulant laxatives
0.007 0.993 0.000
T50.8 Diagnostic agents
0.007 0.993 0.000
T45.0 Antiallergic and antiemetic drugs
0.007 0.993 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.007 0.993 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.007 0.993 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.007 0.993 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.007 0.993 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.007 0.993 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.007 0.993 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.007 0.993 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.007 0.993 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.007 0.993 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.007 0.993 0.000
T44.0 Anticholinesterase agents
0.007 0.993 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.007 0.993 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.007 0.993 0.000
T42.3 Barbiturates
0.007 0.993 0.000
T39.4 Antirheumatics, not elsewhere classified
0.007 0.993 0.000
T39.2 Pyrazolone derivatives
0.007 0.993 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.007 0.993 0.000
T45.5 Anticoagulants
0.006 0.993 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.006 0.993 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.006 0.994 0.000
T48.5 Anti-common-cold drugs
0.006 0.994 0.000
T48.4 Expectorants
0.006 0.994 0.000
T48.3 Antitussives
0.006 0.994 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.006 0.994 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.006 0.994 0.000
T48.0 Oxytocic drugs
0.006 0.994 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.006 0.994 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.006 0.994 0.000
T45.8 Other primarily systemic and haematological agents
0.006 0.994 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.006 0.994 0.000
T45.6 Fibrinolysis-affecting drugs
0.006 0.994 0.000
T45.4 Iron and its compounds
0.006 0.994 0.000
T45.3 Enzymes, not elsewhere classified
0.006 0.994 0.000
T50.7 Analeptics and opioid receptor antagonists
0.006 0.994 0.000
T50.5 Appetite depressants
0.006 0.994 0.000
T50.4 Drugs affecting uric acid metabolism
0.006 0.994 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.006 0.994 0.000
T50.1 Loop [high-ceiling] diuretics
0.006 0.994 0.000
T50.0 Mineralocorticoids and their antagonists
0.006 0.994 0.000
D69 Purpura and other haemorrhagic conditions
0.006 0.994 0.000
T42.1 Iminostilbenes
0.006 0.994 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.006 0.994 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.006 0.994 0.000
T42.2 Succinimides and oxazolidinediones
0.006 0.994 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.006 0.994 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.006 0.994 0.000
T46.1 Calcium-channel blockers
0.006 0.994 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.006 0.994 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.006 0.994 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.006 0.994 0.000
T37.5 Antiviral drugs
0.006 0.994 0.000
T37.4 Anthelminthics
0.006 0.994 0.000
T37.3 Other antiprotozoal drugs
0.006 0.994 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.006 0.994 0.000
T37.1 Antimycobacterial drugs
0.006 0.994 0.000
T37.0 Sulphonamides
0.006 0.994 0.000
T41.5 Therapeutic gases
0.006 0.994 0.000
T41.4 Anaesthetic, unspecified
0.006 0.994 0.000
T41.3 Local anaesthetics
0.006 0.994 0.000
T41.2 Other and unspecified general anaesthetics
0.006 0.994 0.000
T41.1 Intravenous anaesthetics
0.006 0.994 0.000
T41.0 Inhaled anaesthetics
0.006 0.994 0.000
T49.9 Topical agent, unspecified
0.006 0.994 0.000
T49.8 Other topical agents
0.006 0.994 0.000
T49.7 Dental drugs, topically applied
0.006 0.994 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.006 0.994 0.000
T49.5 Ophthalmological drugs and preparations
0.006 0.994 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.006 0.994 0.000
T49.3 Emollients, demulcents and protectants
0.006 0.994 0.000
T49.2 Local astringents and local detergents
0.006 0.994 0.000
T49.1 Antipruritics
0.006 0.994 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.006 0.994 0.000
T36.9 Systemic antibiotic, unspecified
0.006 0.994 0.000
T36.8 Other systemic antibiotics
0.006 0.994 0.000
T36.7 Antifungal antibiotics, systemically used
0.006 0.994 0.000
T36.6 Rifamycins
0.006 0.994 0.000
T36.5 Aminoglycosides
0.006 0.994 0.000
T36.4 Tetracyclines
0.006 0.994 0.000
T36.3 Macrolides
0.006 0.994 0.000
T36.2 Chloramphenicol group
0.006 0.994 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.006 0.994 0.000
T36.0 Penicillins
0.006 0.994 0.000
T42.0 Hydantoin derivatives
0.006 0.994 0.000
T45.2 Vitamins, not elsewhere classified
0.005 0.994 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.005 0.994 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.005 0.994 0.000
T46.7 Peripheral vasodilators
0.005 0.994 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.005 0.994 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.005 0.994 0.000
K83 Other diseases of biliary tract
0.000 0.994 0.006
D69.3 Idiopathic thrombocytopenic purpura
0.005 0.995 0.000
T82.3 Mechanical complication of other vascular grafts
0.005 0.995 0.000
D69.4 Other primary thrombocytopenia
0.005 0.995 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.005 0.995 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.005 0.995 0.000
I15.1 Hypertension secondary to other renal disorders
0.005 0.995 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.005 0.995 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.000 0.995 0.005
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.005 0.995 0.000
T38.9 Other and unspecified hormone antagonists
0.005 0.995 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.005 0.995 0.000
T38.7 Androgens and anabolic congeners
0.005 0.995 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.005 0.995 0.000
T38.5 Other oestrogens and progestogens
0.005 0.995 0.000
T38.4 Oral contraceptives
0.005 0.995 0.000
T38.2 Antithyroid drugs
0.005 0.995 0.000
T38.0 Glucocorticoids and synthetic analogues
0.005 0.995 0.000
G30 Alzheimer's disease
0.000 0.995 0.005
D89.2 Hypergammaglobulinaemia, unspecified
0.005 0.995 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.005 0.995 0.000
D69.8 Other specified haemorrhagic conditions
0.005 0.995 0.000
D69.1 Qualitative platelet defects
0.005 0.995 0.000
D69.2 Other nonthrombocytopenic purpura
0.005 0.995 0.000
T38.1 Thyroid hormones and substitutes
0.005 0.995 0.000
N80.0 Endometriosis of uterus
0.000 0.995 0.005
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.005 0.995 0.000
D69.9 Haemorrhagic condition, unspecified
0.005 0.995 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.005 0.995 0.000
K83.0 Cholangitis
0.000 0.995 0.005
K55.8 Other vascular disorders of intestine
0.004 0.995 0.000
G30.0 Alzheimer's disease with early onset
0.000 0.995 0.004
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.004 0.995 0.000
T42.4 Benzodiazepines
0.004 0.995 0.000
R59.9 Enlarged lymph nodes, unspecified
0.000 0.996 0.004
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.004 0.996 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.004 0.996 0.000
K55 Vascular disorders of intestine
0.004 0.996 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.004 0.996 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.004 0.996 0.000
K83.5 Biliary cyst
0.000 0.996 0.004
K83.4 Spasm of sphincter of Oddi
0.000 0.996 0.004
K83.2 Perforation of bile duct
0.000 0.996 0.004
I15.9 Seconday hypertension, unspecified
0.004 0.996 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.004 0.996 0.000
K83.9 Disease of biliary tract, unspecified
0.000 0.996 0.004
M96.8 Other postprocedural musculoskeletal disorders
0.004 0.996 0.000
I15 Secondary hypertension
0.004 0.996 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.004 0.996 0.000
K83.3 Fistula of bile duct
0.000 0.996 0.004
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.004 0.996 0.000
K55.1 Chronic vascular disorders of intestine
0.004 0.996 0.000
D69.5 Secondary thrombocytopenia
0.004 0.996 0.000
G30.8 Other Alzheimer's disease
0.000 0.996 0.004
G30.1 Alzheimer's disease with late onset
0.000 0.996 0.004
N76.0 Acute vaginitis
0.004 0.996 0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.004 0.996 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.004 0.996 0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.004 0.996 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.003 0.996 0.000
T40.8 Lysergide [LSD]
0.003 0.996 0.000
T40.7 Cannabis (derivatives)
0.003 0.996 0.000
T40.5 Cocaine
0.003 0.996 0.000
T40.3 Methadone
0.003 0.996 0.000
T40.1 Heroin
0.003 0.996 0.000
T40.0 Opium
0.003 0.996 0.000
D80-D89 Certain disorders involving the immune mechanism
0.004 0.996 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.996 0.004
D89.0 Polyclonal hypergammaglobulinaemia
0.003 0.996 0.000
I15.0 Renovascular hypertension
0.004 0.996 0.000
J03.9 Acute tonsillitis, unspecified
0.000 0.996 0.003
K14.9 Disease of tongue, unspecified
0.000 0.997 0.003
J38.7 Other diseases of larynx
0.000 0.997 0.003
K14.8 Other diseases of tongue
0.000 0.997 0.003
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.003 0.997 0.000
D69.0 Allergic purpura
0.003 0.997 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.003 0.997 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.003 0.997 0.000
D89.3 Immune reconstitution syndrome
0.003 0.997 0.000
D89.1 Cryoglobulinaemia
0.003 0.997 0.000
D04.7 Skin of lower limb, including hip
0.003 0.997 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.003 0.997 0.000
I15.8 Other secondary hypertension
0.003 0.997 0.000
I15.2 Hypertension secondary to endocrine disorders
0.003 0.997 0.000
T40.6 Other and unspecified narcotics
0.003 0.997 0.000
D83 Common variable immunodeficiency
0.003 0.997 0.000
D55-D59 Haemolytic anaemias
0.003 0.997 0.000
D80 Immunodeficiency with predominantly antibody defects
0.003 0.997 0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.003 0.997 0.000
M96.5 Postradiation scoliosis
0.003 0.997 0.000
M96.4 Postsurgical lordosis
0.003 0.997 0.000
M96.3 Postlaminectomy kyphosis
0.003 0.997 0.000
M96.2 Postradiation kyphosis
0.003 0.997 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.003 0.997 0.000
T40.4 Other synthetic narcotics
0.003 0.997 0.000
D84 Other immunodeficiencies
0.003 0.997 0.000
Q66.8 Other congenital deformities of feet
0.003 0.997 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.003 0.997 0.000
D56 Thalassaemia
0.003 0.997 0.000
D82 Immunodeficiency associated with other major defects
0.003 0.997 0.000
D81 Combined immunodeficiencies
0.003 0.997 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.003 0.997 0.000
D83.9 Common variable immunodeficiency, unspecified
0.003 0.997 0.000
K14 Diseases of tongue
0.000 0.997 0.003
M95.0 Acquired deformity of nose
0.003 0.997 0.000
M95.4 Acquired deformity of chest and rib
0.003 0.997 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.003 0.997 0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.003 0.997 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.003 0.997 0.000
D58 Other hereditary haemolytic anaemias
0.003 0.997 0.000
D56.1 Beta thalassaemia
0.003 0.997 0.000
D84.9 Immunodeficiency, unspecified
0.003 0.997 0.000
M95.2 Other acquired deformity of head
0.003 0.997 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.003 0.997 0.000
D75.1 Secondary polycythaemia
0.003 0.997 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.003 0.997 0.000
C25.9 Pancreas, unspecified
0.000 0.997 0.003
D56.3 Thalassaemia trait
0.003 0.997 0.000
D57 Sickle-cell disorders
0.003 0.997 0.000
O16 Unspecified maternal hypertension
0.003 0.997 0.000
M41.9 Scoliosis, unspecified
0.003 0.997 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.002 0.997 0.000
D83.8 Other common variable immunodeficiencies
0.002 0.997 0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.002 0.997 0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.002 0.997 0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.002 0.997 0.000
M67.1 Other contracture of tendon (sheath)
0.003 0.997 0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
0.003 0.997 0.000
Y44.2 Anticoagulants
0.003 0.997 0.000
D55 Anaemia due to enzyme disorders
0.002 0.997 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.002 0.997 0.000
D80.8 Other immunodeficiencies with predominantly antibody defects
0.002 0.997 0.000
D80.7 Transient hypogammaglobulinaemia of infancy
0.002 0.997 0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.002 0.997 0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.002 0.997 0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.002 0.997 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.002 0.997 0.000
D80.0 Hereditary hypogammaglobulinaemia
0.002 0.997 0.000
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)
0.002 0.997 0.000
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate
0.002 0.997 0.000
D84.8 Other specified immunodeficiencies
0.002 0.997 0.000
D84.1 Defects in the complement system
0.002 0.997 0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.002 0.997 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.002 0.997 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.002 0.998 0.000
D58.0 Hereditary spherocytosis
0.002 0.998 0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified
0.002 0.998 0.000
M95.8 Other specified acquired deformities of musculoskeletal system
0.002 0.998 0.000
M95.5 Acquired deformity of pelvis
0.002 0.998 0.000
M95.3 Acquired deformity of neck
0.002 0.998 0.000
M95.1 Cauliflower ear
0.002 0.998 0.000
D56.9 Thalassaemia, unspecified
0.002 0.998 0.000
D56.8 Other thalassaemias
0.002 0.998 0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.002 0.998 0.000
D56.2 Delta-beta thalassaemia
0.002 0.998 0.000
D56.0 Alpha thalassaemia
0.002 0.998 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.002 0.998 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.002 0.998 0.000
S70.1 Contusion of thigh
0.000 0.998 0.002
D81.9 Combined immunodeficiency, unspecified
0.002 0.998 0.000
D81.8 Other combined immunodeficiencies
0.002 0.998 0.000
D81.7 Major histocompatibility complex class II deficiency
0.002 0.998 0.000
D81.6 Major histocompatibility complex class I deficiency
0.002 0.998 0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.002 0.998 0.000
D81.4 Nezelof's syndrome
0.002 0.998 0.000
D81.3 Adenosine deaminase [ADA] deficiency
0.002 0.998 0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.002 0.998 0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.002 0.998 0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.002 0.998 0.000
D82.9 Immunodeficiency associated with major defect, unspecified
0.002 0.998 0.000
D82.8 Immunodeficiency associated with other specified major defects
0.002 0.998 0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.002 0.998 0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.002 0.998 0.000
D82.2 Immunodeficiency with short-limbed stature
0.002 0.998 0.000
D82.1 Di George's syndrome
0.002 0.998 0.000
D82.0 Wiskott-Aldrich syndrome
0.002 0.998 0.000
G44.2 Tension-type headache
0.002 0.998 0.000
K14.0 Glossitis
0.000 0.998 0.002
Q66.3 Other congenital varus deformities of feet
0.002 0.998 0.000
D59 Acquired haemolytic anaemia
0.002 0.998 0.000
K14.5 Plicated tongue
0.000 0.998 0.002
K14.4 Atrophy of tongue papillae
0.000 0.998 0.002
K14.3 Hypertrophy of tongue papillae
0.000 0.998 0.002
K14.2 Median rhomboid glossitis
0.000 0.998 0.002
K14.1 Geographic tongue
0.000 0.998 0.002
D58.9 Hereditary haemolytic anaemia, unspecified
0.002 0.998 0.000
T40.2 Other opioids
0.002 0.998 0.000
D57.1 Sickle-cell anaemia without crisis
0.002 0.998 0.000
D58.8 Other specified hereditary haemolytic anaemias
0.002 0.998 0.000
D58.2 Other haemoglobinopathies
0.002 0.998 0.000
D58.1 Hereditary elliptocytosis
0.002 0.998 0.000
K14.6 Glossodynia
0.000 0.998 0.002
Q66 Congenital deformities of feet
0.002 0.998 0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.002 0.998 0.000
J86.0 Pyothorax with fistula
0.002 0.998 0.000
D57.8 Other sickle-cell disorders
0.002 0.998 0.000
D57.3 Sickle-cell trait
0.002 0.998 0.000
D57.2 Double heterozygous sickling disorders
0.002 0.998 0.000
D57.0 Sickle-cell anaemia with crisis
0.002 0.998 0.000
D59.0 Drug-induced autoimmune haemolytic anaemia
0.002 0.998 0.000
R23.8 Other and unspecified skin changes
0.000 0.998 0.002
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.002 0.998 0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.002 0.998 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.002 0.998 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.002 0.998 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.002 0.998 0.000
D55.9 Anaemia due to enzyme disorder, unspecified
0.002 0.998 0.000
D55.8 Other anaemias due to enzyme disorders
0.002 0.998 0.000
D55.3 Anaemia due to disorders of nucleotide metabolism
0.002 0.998 0.000
D55.2 Anaemia due to disorders of glycolytic enzymes
0.002 0.998 0.000
D55.1 Anaemia due to other disorders of glutathione metabolism
0.002 0.998 0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.002 0.998 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.002 0.998 0.000
M99 Biomechanical lesions, not elsewhere classified
0.002 0.998 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.002 0.998 0.000
N21.0 Calculus in bladder
0.000 0.998 0.002
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.002 0.998 0.000
S06.80 Other intracranial injuries (without open intracranial wound)
0.002 0.998 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.000 0.998 0.002
K55.9 Vascular disorder of intestine, unspecified
0.002 0.998 0.000
O97 Death from sequelae of direct obstetric causes
0.002 0.998 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.002 0.998 0.000
O95 Obstetric death of unspecified cause
0.002 0.998 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.002 0.998 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.002 0.998 0.000
M95.96 Acquired deformity of musculoskeletal system, unspecified
0.002 0.998 0.000
N76.3 Subacute and chronic vulvitis
0.002 0.998 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.000 0.998 0.002
J17.0 Pneumonia in bacterial diseases classified elsewhere
0.002 0.998 0.000
D59.8 Other acquired haemolytic anaemias
0.002 0.998 0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.002 0.998 0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.002 0.998 0.000
D59.4 Other nonautoimmune haemolytic anaemias
0.002 0.998 0.000
D59.3 Haemolytic-uraemic syndrome
0.002 0.998 0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.002 0.998 0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.002 0.998 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.000 0.998 0.002
E21.3 Hyperparathyroidism, unspecified
0.000 0.998 0.002
O32.1 Maternal care for breech presentation
0.000 0.998 0.002
M41.94 Scoliosis, unspecified (Thoracic region)
0.002 0.998 0.000
D59.9 Acquired haemolytic anaemia, unspecified
0.002 0.998 0.000
H34.2 Other retinal artery occlusions
0.002 0.998 0.000
J18.0 Bronchopneumonia, unspecified
0.002 0.998 0.000
Q66.9 Congenital deformity of feet, unspecified
0.002 0.998 0.000
Q66.6 Other congenital valgus deformities of feet
0.002 0.998 0.000
Q66.5 Congenital pes planus
0.002 0.998 0.000
Q66.4 Talipes calcaneovalgus
0.002 0.998 0.000
Q66.2 Metatarsus varus
0.002 0.998 0.000
Q66.1 Talipes calcaneovarus
0.002 0.998 0.000
Q66.0 Talipes equinovarus
0.002 0.998 0.000
Z46.8 Fitting and adjustment of other specified devices
0.000 0.998 0.002
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.002 0.998 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.002 0.998 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.002 0.998 0.000
O70.2 Third degree perineal laceration during delivery
0.002 0.998 0.000
Q66.7 Pes cavus
0.002 0.998 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.998 0.002
M99.9 Biomechanical lesion, unspecified
0.002 0.998 0.000
M99.8 Other biomechanical lesions
0.002 0.998 0.000
M99.7 Connective tissue and disk stenosis of intervertebral foramina
0.002 0.998 0.000
M99.6 Osseous and subluxation stenosis of intervertebral foramina
0.002 0.998 0.000
M99.4 Connective tissue stenosis of neural canal
0.002 0.998 0.000
M99.3 Osseous stenosis of neural canal
0.002 0.998 0.000
M99.2 Subluxation stenosis of neural canal
0.002 0.998 0.000
M99.1 Subluxation complex (vertebral)
0.002 0.998 0.000
M99.0 Segmental and somatic dysfunction
0.002 0.998 0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium
0.002 0.998 0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium
0.002 0.998 0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium
0.002 0.998 0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium
0.002 0.998 0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium
0.002 0.998 0.000
N76 Other inflammation of vagina and vulva
0.002 0.998 0.000
O96.9 Death from unspecified obstetric cause
0.002 0.998 0.000
O96.1 Death from indirect obstetric cause
0.002 0.998 0.000
O96.0 Death from direct obstetric cause
0.002 0.998 0.000
O97.9 Death from sequelae of obstetric cause, unspecified
0.002 0.998 0.000
O97.1 Death from sequelae of indirect obstetric cause
0.002 0.998 0.000
O97.0 Death from sequelae of direct obstetric cause
0.002 0.998 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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