TreeWAS – Variant ID: rs12530421

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.002	0.998
E03.9 Hypothyroidism, unspecified	0.000	0.023	0.977
L40.0 Psoriasis vulgaris	0.956	0.044	0.000
E03 Other hypothyroidism	0.000	0.168	0.832
L40.8 Other psoriasis	0.786	0.214	0.000
E00-E07 Disorders of thyroid gland	0.000	0.280	0.720
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
L40.1 Generalised pustular psoriasis	0.717	0.283	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.337	0.663
E03.8 Other specified hypothyroidism	0.000	0.361	0.639
E05.9 Thyrotoxicosis, unspecified	0.000	0.367	0.633
E03.5 Myxoedema coma	0.000	0.403	0.597
E03.4 Atrophy of thyroid (acquired)	0.000	0.403	0.597
E03.3 Postinfectious hypothyroidism	0.000	0.403	0.597
E03.1 Congenital hypothyroidism without goitre	0.000	0.403	0.597
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.403	0.597
E06 Thyroiditis	0.000	0.425	0.575
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.433	0.567
E07 Other disorders of thyroid	0.000	0.454	0.546
L40-L45 Papulosquamous disorders	0.540	0.459	0.000
K90 Intestinal malabsorption	0.000	0.470	0.530
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.473	0.527
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.483	0.516
E00 Congenital iodine-deficiency syndrome	0.000	0.483	0.516
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.483	0.516
M07.3 Other psoriatic arthropathies	0.488	0.512	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.484	0.516	0.000
E05.8 Other thyrotoxicosis	0.000	0.524	0.476
E05.5 Thyroid crisis or storm	0.000	0.524	0.476
E05.4 Thyrotoxicosis factitia	0.000	0.524	0.476
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.524	0.476
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.524	0.476
M07.30 Other psoriatic arthropathies (Multiple sites)	0.470	0.530	0.000
E06.3 Autoimmune thyroiditis	0.000	0.530	0.469
M07 Psoriatic and enteropathic arthropathies	0.464	0.536	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.447	0.553	0.000
M05-M14 Inflammatory polyarthropathies	0.446	0.554	0.000
M70-M79 Other soft tissue disorders	0.446	0.554	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.442	0.558	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.561	0.439
M79.0 Rheumatism, unspecified	0.436	0.564	0.000
E04 Other non-toxic goitre	0.000	0.576	0.424
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.580	0.420
M86-M90 Other osteopathies	0.420	0.580	0.000
E06.9 Thyroiditis, unspecified	0.000	0.584	0.416
M79.09 Rheumatism, unspecified (Site unspecified)	0.413	0.587	0.000
E06.5 Other chronic thyroiditis	0.000	0.587	0.413
E06.4 Drug-induced thyroiditis	0.000	0.587	0.413
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.587	0.413
E06.1 Subacute thyroiditis	0.000	0.587	0.413
E06.0 Acute thyroiditis	0.000	0.587	0.413
M45-M49 Spondylopathies	0.409	0.591	0.000
M77 Other enthesopathies	0.405	0.595	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.402	0.598	0.000
M60-M63 Disorders of muscles	0.399	0.601	0.000
M79.1 Myalgia	0.397	0.603	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.001	0.605	0.394
M91-M94 Chondropathies	0.392	0.608	0.000
E07.1 Dyshormogenetic goitre	0.000	0.608	0.392
E07.0 Hypersecretion of calcitonin	0.000	0.608	0.392
M07.34 Other psoriatic arthropathies (Hand)	0.391	0.609	0.000
M46 Other inflammatory spondylopathies	0.388	0.612	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.388	0.612	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.612	0.388
L44 Other papulosquamous disorders	0.388	0.612	0.000
L41 Parapsoriasis	0.388	0.612	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.388	0.612	0.000
L42 Pityriasis rosea	0.388	0.612	0.000
M89 Other disorders of bone	0.384	0.616	0.000
K90.8 Other intestinal malabsorption	0.000	0.620	0.380
K90.3 Pancreatic steatorrhoea	0.000	0.620	0.380
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.620	0.380
K90.1 Tropical sprue	0.000	0.620	0.380
M79.2 Neuralgia and neuritis, unspecified	0.380	0.620	0.000
M71 Other bursopathies	0.377	0.623	0.000
M79.7 Fibromyalgia	0.374	0.626	0.000
M10 Gout	0.374	0.626	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.629	0.370
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.629	0.370
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.629	0.370
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.629	0.370
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.629	0.370
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.629	0.370
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.629	0.370
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.629	0.370
E07.8 Other specified disorders of thyroid	0.000	0.633	0.367
M62 Other disorders of muscle	0.365	0.635	0.000
E10 Insulin-dependent diabetes mellitus	0.000	0.636	0.364
M46.9 Inflammatory spondylopathy, unspecified	0.364	0.636	0.000
E10-E14 Diabetes mellitus	0.000	0.636	0.363
M79.08 Rheumatism, unspecified (Other)	0.361	0.639	0.000
E10.9 Without complications	0.000	0.640	0.360
M89.9 Disorder of bone, unspecified	0.357	0.643	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.355	0.645	0.000
M94 Other disorders of cartilage	0.351	0.648	0.000
M07.38 Other psoriatic arthropathies (Other)	0.350	0.650	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.350	0.650	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.350	0.650	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.350	0.650	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.350	0.650	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.350	0.650	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.656	0.344
M62.8 Other specified disorders of muscle	0.340	0.660	0.000
M77.0 Medial epicondylitis	0.340	0.660	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.339	0.661	0.000
M79.9 Soft tissue disorder, unspecified	0.337	0.663	0.000
M47 Spondylosis	0.337	0.663	0.000
M87 Osteonecrosis	0.337	0.663	0.000
M79.11 Myalgia (Shoulder region)	0.336	0.664	0.000
M00-M03 Infectious arthropathies	0.335	0.665	0.000
M07.6 Other enteropathic arthropathies	0.333	0.667	0.000
M07.5 Arthropathy in ulcerative colitis	0.333	0.667	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.333	0.667	0.000
M07.2 Psoriatic spondylitis	0.333	0.667	0.000
M07.1 Arthritis mutilans	0.333	0.667	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.333	0.667	0.000
M76 Enthesopathies of lower limb, excluding foot	0.331	0.669	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.330	0.670	0.000
M47.8 Other spondylosis	0.330	0.670	0.000
M90 Osteopathies in diseases classified elsewhere	0.329	0.670	0.000
M77.1 Lateral epicondylitis	0.329	0.671	0.000
M14 Arthropathies in other diseases classified elsewhere	0.324	0.676	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.323	0.677	0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.323	0.677	0.000
M10.9 Gout, unspecified	0.322	0.678	0.000
M72 Fibroblastic disorders	0.322	0.678	0.000
E27 Other disorders of adrenal gland	0.000	0.678	0.322
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.322	0.678	0.000
M12 Other specific arthropathies	0.320	0.680	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.320	0.680	0.000
M08 Juvenile arthritis	0.320	0.680	0.000
M46.4 Discitis, unspecified	0.320	0.680	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.320	0.680	0.000
M79.19 Myalgia (Site unspecified)	0.317	0.682	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.001	0.683	0.317
M79.3 Panniculitis, unspecified	0.317	0.683	0.000
M71.2 Synovial cyst of popliteal space [Baker]	0.315	0.685	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.314	0.686	0.000
M77.9 Enthesopathy, unspecified	0.314	0.686	0.000
M77.4 Metatarsalgia	0.314	0.686	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.313	0.687	0.000
M79.07 Rheumatism, unspecified (Ankle and foot)	0.313	0.687	0.000
M79.06 Rheumatism, unspecified (Lower leg)	0.313	0.687	0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.313	0.687	0.000
M79.04 Rheumatism, unspecified (Hand)	0.313	0.687	0.000
M79.03 Rheumatism, unspecified (Forearm)	0.313	0.687	0.000
M79.02 Rheumatism, unspecified (Upper arm)	0.313	0.687	0.000
M79.01 Rheumatism, unspecified (Shoulder region)	0.313	0.687	0.000
M94.8 Other specified disorders of cartilage	0.312	0.688	0.000
M89.3 Hypertrophy of bone	0.311	0.688	0.000
M79.18 Myalgia (Other)	0.311	0.689	0.000
M79.15 Myalgia (Pelvic region and thigh)	0.308	0.692	0.000
M49 Spondylopathies in diseases classified elsewhere	0.308	0.692	0.000
E10.3 With ophthalmic complications	0.000	0.692	0.308
M50-M54 Other dorsopathies	0.306	0.694	0.000
M40-M43 Deforming dorsopathies	0.306	0.694	0.000
M79.70 Fibromyalgia (Multiple sites)	0.305	0.694	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.695	0.305
E04.2 Non-toxic multinodular goitre	0.000	0.695	0.305
E04.8 Other specified non-toxic goitre	0.000	0.695	0.304
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.304	0.696	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.697	0.303
L57.0 Actinic keratosis	0.303	0.697	0.000
E40-E46 Malnutrition	0.000	0.697	0.302
M86 Osteomyelitis	0.302	0.698	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.301	0.699	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.300	0.700	0.000
M79.79 Fibromyalgia (Site unspecified)	0.299	0.701	0.000
M88 Paget's disease of bone [osteitis deformans]	0.298	0.702	0.000
M62.88 Other specified disorders of muscle (Other)	0.297	0.703	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.295	0.705	0.000
M47.89 Other spondylosis (Site unspecified)	0.295	0.705	0.000
M47.86 Other spondylosis (Lumbar region)	0.295	0.705	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.294	0.705	0.000
M77.02 Medial epicondylitis (Upper arm)	0.293	0.707	0.000
M71.3 Other bursal cyst	0.292	0.708	0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.292	0.708	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.709	0.291
M77.8 Other enthesopathies, not elsewhere classified	0.291	0.709	0.000
M77.3 Calcaneal spur	0.291	0.709	0.000
M77.2 Periarthritis of wrist	0.291	0.709	0.000
M79.5 Residual foreign body in soft tissue	0.291	0.709	0.000
M65-M68 Disorders of synovium and tendon	0.290	0.710	0.000
M94.88 Other specified disorders of cartilage (Other)	0.289	0.711	0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.288	0.712	0.000
E10.4 With neurological complications	0.000	0.713	0.287
M63 Disorders of muscle in diseases classified elsewhere	0.286	0.714	0.000
M61 Calcification and ossification of muscle	0.286	0.714	0.000
M60 Myositis	0.286	0.714	0.000
M77.5 Other enthesopathy of foot	0.286	0.714	0.000
M79.17 Myalgia (Ankle and foot)	0.284	0.715	0.000
M79.14 Myalgia (Hand)	0.284	0.715	0.000
M79.13 Myalgia (Forearm)	0.284	0.715	0.000
M79.12 Myalgia (Upper arm)	0.284	0.715	0.000
M79.16 Myalgia (Lower leg)	0.284	0.716	0.000
M89.5 Osteolysis	0.283	0.716	0.000
M50 Cervical disk disorders	0.283	0.717	0.000
M11 Other crystal arthropathies	0.282	0.718	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.280	0.720	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.279	0.721	0.000
M89.0 Algoneurodystrophy	0.279	0.721	0.000
E10.1 With ketoacidosis	0.000	0.721	0.279
M46.8 Other specified inflammatory spondylopathies	0.278	0.722	0.000
M46.5 Other infective spondylopathies	0.278	0.722	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.278	0.722	0.000
M46.2 Osteomyelitis of vertebra	0.278	0.722	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.278	0.722	0.000
M46.0 Spinal enthesopathy	0.278	0.722	0.000
M92 Other juvenile osteochondrosis	0.278	0.722	0.000
L41.9 Parapsoriasis, unspecified	0.278	0.722	0.000
L41.8 Other parapsoriasis	0.278	0.722	0.000
L41.5 Retiform parapsoriasis	0.278	0.722	0.000
L41.4 Large plaque parapsoriasis	0.278	0.722	0.000
L41.3 Small plaque parapsoriasis	0.278	0.722	0.000
L41.2 Lymphomatoid papulosis	0.278	0.722	0.000
L41.1 Pityriasis lichenoides chronica	0.278	0.722	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.278	0.722	0.000
L44.9 Papulosquamous disorder, unspecified	0.278	0.722	0.000
L44.8 Other specified papulosquamous disorders	0.278	0.722	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.278	0.722	0.000
L44.3 Lichen ruber moniliformis	0.278	0.722	0.000
L44.2 Lichen striatus	0.278	0.722	0.000
L44.1 Lichen nitidus	0.278	0.722	0.000
L44.0 Pityriasis rubra pilaris	0.278	0.722	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.276	0.724	0.000
M89.6 Osteopathy after poliomyelitis	0.275	0.725	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.275	0.725	0.000
M89.2 Other disorders of bone development and growth	0.275	0.725	0.000
M89.1 Epiphyseal arrest	0.275	0.725	0.000
M50.3 Other cervical disk degeneration	0.275	0.725	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.275	0.725	0.000
M93 Other osteochondropathies	0.274	0.725	0.000
E10.2 With renal complications	0.000	0.726	0.274
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.273	0.726	0.000
M10.99 Gout, unspecified (Site unspecified)	0.273	0.727	0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.272	0.727	0.000
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.272	0.727	0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.272	0.727	0.000
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.272	0.727	0.000
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.272	0.727	0.000
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.272	0.727	0.000
L81.4 Other melanin hyperpigmentation	0.272	0.728	0.000
L81 Other disorders of pigmentation	0.271	0.729	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.271	0.729	0.000
L10-L14 Bullous disorders	0.271	0.729	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.271	0.729	0.000
M71.9 Bursopathy, unspecified	0.270	0.730	0.000
M71.8 Other specified bursopathies	0.270	0.730	0.000
M71.5 Other bursitis, not elsewhere classified	0.270	0.730	0.000
M71.4 Calcium deposit in bursa	0.270	0.730	0.000
M71.1 Other infective bursitis	0.270	0.730	0.000
M71.0 Abscess of bursa	0.270	0.730	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.270	0.730	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.270	0.730	0.000
E28 Ovarian dysfunction	0.000	0.730	0.270
M87.9 Osteonecrosis, unspecified	0.270	0.730	0.000
L43 Lichen planus	0.269	0.730	0.000
M72.2 Plantar fascial fibromatosis	0.269	0.731	0.000
M79.78 Fibromyalgia (Other)	0.268	0.731	0.000
M79.77 Fibromyalgia (Ankle and foot)	0.268	0.731	0.000
M79.76 Fibromyalgia (Lower leg)	0.268	0.731	0.000
M79.75 Fibromyalgia (Pelvic region and thigh)	0.268	0.731	0.000
M79.74 Fibromyalgia (Hand)	0.268	0.731	0.000
M79.73 Fibromyalgia (Forearm)	0.268	0.731	0.000
M79.72 Fibromyalgia (Upper arm)	0.268	0.731	0.000
M79.71 Fibromyalgia (Shoulder region)	0.268	0.731	0.000
M10.4 Other secondary gout	0.268	0.732	0.000
M10.3 Gout due to impairment of renal function	0.268	0.732	0.000
M10.2 Drug-induced gout	0.268	0.732	0.000
M10.1 Lead-induced gout	0.268	0.732	0.000
M10.0 Idiopathic gout	0.268	0.732	0.000
M94.2 Chondromalacia	0.268	0.732	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.267	0.733	0.000
L60-L75 Disorders of skin appendages	0.266	0.734	0.000
M79.46 Hypertrophy of (infrapatellar) fat pad (Lower leg)	0.265	0.735	0.000
M90.7 Fracture of bone in neoplastic disease	0.265	0.735	0.000
M94.9 Disorder of cartilage, unspecified	0.265	0.735	0.000
M79.96 Soft tissue disorder, unspecified (Lower leg)	0.262	0.738	0.000
M62.9 Disorder of muscle, unspecified	0.261	0.738	0.000
M62.6 Muscle strain	0.261	0.738	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.261	0.738	0.000
M62.4 Contracture of muscle	0.261	0.738	0.000
M62.3 Immobility syndrome (paraplegic)	0.261	0.738	0.000
M62.2 Ischaemic infarction of muscle	0.261	0.738	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.261	0.738	0.000
M62.0 Diastasis of muscle	0.261	0.738	0.000
E10.8 With unspecified complications	0.000	0.739	0.261
E10.7 With multiple complications	0.000	0.739	0.261
E10.0 With coma	0.000	0.739	0.261
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.261	0.739	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.261	0.739	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.261	0.739	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.261	0.739	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.261	0.739	0.000
M80-M85 Disorders of bone density and structure	0.261	0.739	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.739	0.261
M06 Other rheumatoid arthritis	0.260	0.739	0.001
M79.28 Neuralgia and neuritis, unspecified (Other)	0.260	0.740	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.260	0.740	0.000
M05 Seropositive rheumatoid arthritis	0.259	0.741	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.258	0.742	0.000
E50-E64 Other nutritional deficiencies	0.000	0.742	0.257
M62.86 Other specified disorders of muscle (Lower leg)	0.257	0.743	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.257	0.743	0.000
E22 Hyperfunction of pituitary gland	0.000	0.744	0.256
M89.99 Disorder of bone, unspecified (Site unspecified)	0.256	0.744	0.000
M89.98 Disorder of bone, unspecified (Other)	0.256	0.744	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.256	0.744	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.256	0.744	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.256	0.744	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.256	0.744	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.255	0.745	0.000
M00 Pyogenic arthritis	0.255	0.745	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.254	0.746	0.000
M79.10 Myalgia (Multiple sites)	0.254	0.746	0.000
M87.2 Osteonecrosis due to previous trauma	0.253	0.747	0.000
M94.3 Chondrolysis	0.252	0.748	0.000
M94.1 Relapsing polychondritis	0.252	0.748	0.000
M94.0 Chondrocostal junction syndrome [Tietze]	0.252	0.748	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.251	0.749	0.000
E10.5 With peripheral circulatory complications	0.000	0.749	0.251
M70.6 Trochanteric bursitis	0.250	0.750	0.000
E20 Hypoparathyroidism	0.000	0.751	0.249
E29 Testicular dysfunction	0.000	0.751	0.249
M76.6 Achilles tendinitis	0.249	0.751	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.248	0.752	0.000
E65-E68 Obesity and other hyperalimentation	0.000	0.752	0.247
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.753	0.247
E32 Diseases of thymus	0.000	0.753	0.247
E31 Polyglandular dysfunction	0.000	0.753	0.247
E30 Disorders of puberty, not elsewhere classified	0.000	0.753	0.247
E25 Adrenogenital disorders	0.000	0.753	0.247
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.001	0.754	0.246
L50-L54 Urticaria and erythema	0.246	0.754	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.754	0.246
M62.89 Other specified disorders of muscle (Site unspecified)	0.244	0.756	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.244	0.756	0.000
M62.84 Other specified disorders of muscle (Hand)	0.244	0.756	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.244	0.756	0.000
M77.09 Medial epicondylitis (Site unspecified)	0.244	0.756	0.000
M77.08 Medial epicondylitis-Other	0.244	0.756	0.000
M77.07 Medial epicondylitis-Ankle/Foot	0.244	0.756	0.000
M77.06 Medial epicondylitis (Lower leg)	0.244	0.756	0.000
M77.05 Medial epicondylitis (Pelvic region and thigh)	0.244	0.756	0.000
M77.04 Medial epicondylitis-Hand	0.244	0.756	0.000
M77.03 Medial epicondylitis-Forearm	0.244	0.756	0.000
M77.01 Medial epicondylitis-Shldr region	0.244	0.756	0.000
M77.00 Medial epicondylitis (Multiple sites)	0.244	0.756	0.000
M79.49 Hypertrophy of (infrapatellar) fat pad-Site unspec	0.243	0.757	0.000
M79.48 Hypertrophy of (infrapatellar) fat pad (Other)	0.243	0.757	0.000
M79.47 Hypertrophy of (infrapatellar) fat pad (Ankle and foot)	0.243	0.757	0.000
M79.45 Hypertrophy of (infrapatellar) fat pad (Pelvic region and thigh)	0.243	0.757	0.000
M79.44 Hypertrophy of (infrapatellar) fat pad (Hand)	0.243	0.757	0.000
M79.43 Hypertrophy of (infrapatellar) fat pad (Forearm)	0.243	0.757	0.000
M79.42 Hypertrophy of (infrapatellar) fat pad (Upper arm)	0.243	0.757	0.000
M79.41 Hypertrophy of (infrapatellar) fat pad (Shoulder region)	0.243	0.757	0.000
M79.40 Hypertrophy of (infrapatellar) fat pad (Multiple sites)	0.243	0.757	0.000
M79.99 Soft tissue disorder, unspecified (Site unspecified)	0.242	0.758	0.000
M79.98 Soft tissue disorder, unspecified (Other)	0.242	0.758	0.000
M79.97 Soft tissue disorder, unspecified (Ankle and foot)	0.242	0.758	0.000
M79.95 Soft tissue disorder, unspecified (Pelvic region and thigh)	0.242	0.758	0.000
M79.94 Soft tissue disorder, unspecified (Hand)	0.242	0.758	0.000
M79.93 Soft tissue disorder, unspecified (Forearm)	0.242	0.758	0.000
M79.92 Soft tissue disorder, unspecified (Upper arm)	0.242	0.758	0.000
M79.91 Soft tissue disorder, unspecified (Shoulder region)	0.242	0.758	0.000
M79.90 Soft tissue disorder, unspecified (Multiple sites)	0.242	0.758	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.242	0.758	0.000
M87.8 Other osteonecrosis	0.242	0.758	0.000
M87.3 Other secondary osteonecrosis	0.242	0.758	0.000
M87.1 Osteonecrosis due to drugs	0.242	0.758	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.242	0.758	0.000
E10.6 With other specified complications	0.000	0.759	0.240
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.240	0.759	0.000
M02 Reactive arthropathies	0.240	0.759	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.240	0.759	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.240	0.760	0.000
M53 Other dorsopathies, not elsewhere classified	0.240	0.760	0.000
E26 Hyperaldosteronism	0.000	0.760	0.240
M10.90 Gout, unspecified (Multiple sites)	0.239	0.761	0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.238	0.761	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.238	0.761	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.238	0.761	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.238	0.761	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.238	0.761	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.238	0.761	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.238	0.761	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.238	0.761	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.238	0.761	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.238	0.761	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.238	0.761	0.000
M07.18 Arthritis mutilans (Other)	0.238	0.761	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.238	0.761	0.000
M07.16 Arthritis mutilans (Lower leg)	0.238	0.761	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.238	0.761	0.000
M07.14 Arthritis mutilans (Hand)	0.238	0.761	0.000
M07.13 Arthritis mutilans (Forearm)	0.238	0.761	0.000
M07.12 Arthritis mutilans (Upper arm)	0.238	0.761	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.238	0.761	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.238	0.761	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.238	0.761	0.000
M07.28 Psoriatic spondylitis (Other)	0.238	0.761	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.238	0.761	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.238	0.761	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.238	0.761	0.000
M07.24 Psoriatic spondylitis (Hand)	0.238	0.761	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.238	0.761	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.238	0.761	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.238	0.761	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.238	0.761	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.238	0.761	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.238	0.761	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.238	0.761	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.238	0.761	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.238	0.761	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.238	0.761	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.238	0.761	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.238	0.761	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.238	0.761	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.238	0.761	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.238	0.761	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.238	0.761	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.238	0.761	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.238	0.761	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.238	0.761	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.238	0.761	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.238	0.761	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.238	0.761	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.238	0.761	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.238	0.761	0.000
M07.69 Other enteropathic arthropathies (Site unspecified)	0.238	0.761	0.000
M07.68 Other enteropathic arthropathies (Other)	0.238	0.761	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.238	0.761	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.238	0.761	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.238	0.761	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.238	0.761	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.238	0.761	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.238	0.761	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.238	0.761	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.238	0.761	0.000
E24 Cushing's syndrome	0.000	0.762	0.238
M76.9 Enthesopathy of lower limb, unspecified	0.237	0.762	0.000
M76.8 Other enthesopathies of lower limb, excluding foot	0.237	0.762	0.000
M76.7 Peroneal tendinitis	0.237	0.762	0.000
M76.5 Patellar tendinitis	0.237	0.762	0.000
M76.4 Tibial collateral bursitis [Pellegrini-Stieda]	0.237	0.762	0.000
M76.3 Iliotibial band syndrome	0.237	0.762	0.000
M76.2 Iliac crest spur	0.237	0.762	0.000
M76.1 Psoas tendinitis	0.237	0.762	0.000
M76.0 Gluteal tendinitis	0.237	0.762	0.000
E46 Unspecified protein-energy malnutrition	0.000	0.763	0.237
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.237	0.763	0.000
L58 Radiodermatitis	0.237	0.763	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.237	0.763	0.000
L55 Sunburn	0.237	0.763	0.000
M14.6 Neuropathic arthropathy	0.237	0.763	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.236	0.763	0.000
M47.84 Other spondylosis (Thoracic region)	0.236	0.763	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.236	0.763	0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.236	0.763	0.000
M90.8 Osteopathy in other diseases classified elsewhere	0.236	0.763	0.000
M90.6 Osteitis deformans in neoplastic disease	0.236	0.763	0.000
M90.5 Osteonecrosis in other diseases classified elsewhere	0.236	0.763	0.000
M90.4 Osteonecrosis due to heamoglobinopathy	0.236	0.763	0.000
M90.3 Osteonecrosis in caisson disease	0.236	0.763	0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.236	0.763	0.000
M90.1 Periostitis in other infectious diseases classified elsewhere	0.236	0.763	0.000
M90.0 Tuberculosis of bone	0.236	0.763	0.000
M77.19 Lateral epicondylitis (Site unspecified)	0.236	0.764	0.000
M77.18 Lateral epicondylitis-Other	0.236	0.764	0.000
M77.17 Lateral epicondylitis-Ankle/Foot	0.236	0.764	0.000
M77.16 Lateral epicondylitis (Lower leg)	0.236	0.764	0.000
M77.15 Lateral epicondylitis (Pelvic region and thigh)	0.236	0.764	0.000
M77.14 Lateral epicondylitis-Hand	0.236	0.764	0.000
M77.13 Lateral epicondylitis-Forearm	0.236	0.764	0.000
M77.11 Lateral epicondylitis-Shldr region	0.236	0.764	0.000
M77.10 Lateral epicondylitis (Multiple sites)	0.236	0.764	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.236	0.764	0.000
L81.8 Other specified disorders of pigmentation	0.236	0.764	0.000
L71 Rosacea	0.234	0.766	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.233	0.767	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.233	0.767	0.000
M14.4 Arthropathy in amyloidosis	0.233	0.767	0.000
M14.3 Lipoid dermatoarthritis	0.233	0.767	0.000
M14.2 Diabetic arthropathy	0.233	0.767	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.233	0.767	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.233	0.767	0.000
M70.2 Olecranon bursitis	0.233	0.767	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.768	0.232
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure	0.232	0.768	0.000
M70.8 Other soft tissue disorders related to use, overuse and pressure	0.232	0.768	0.000
M70.7 Other bursitis of hip	0.232	0.768	0.000
M70.5 Other bursitis of knee	0.232	0.768	0.000
M70.3 Other bursitis of elbow	0.232	0.768	0.000
M70.1 Bursitis of hand	0.232	0.768	0.000
M70.0 Chronic crepitant synovitis of hand and wrist	0.232	0.768	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations