TreeWAS – Variant ID: rs12531458

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K25.7 Chronic without haemorrhage or perforation	0.082	0.918	0.000
K25.4 Chronic or unspecified with haemorrhage	0.074	0.926	0.000
K25 Gastric ulcer	0.073	0.927	0.000
K25.3 Acute without haemorrhage or perforation	0.064	0.936	0.000
K25.5 Chronic or unspecified with perforation	0.058	0.942	0.000
K25.1 Acute with perforation	0.057	0.943	0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.055	0.945	0.000
K25.2 Acute with both haemorrhage and perforation	0.053	0.947	0.000
K25.0 Acute with haemorrhage	0.048	0.952	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.033	0.967	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.030	0.970	0.000
D80 Immunodeficiency with predominantly antibody defects	0.029	0.971	0.000
M13.94 Arthritis, unspecified (Hand)	0.028	0.972	0.000
D80-D89 Certain disorders involving the immune mechanism	0.027	0.973	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.025	0.975	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.025	0.975	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.024	0.976	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.024	0.976	0.000
D83 Common variable immunodeficiency	0.023	0.977	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.022	0.978	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.022	0.978	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.022	0.978	0.000
D89.3 Immune reconstitution syndrome	0.022	0.978	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.022	0.978	0.000
D89.1 Cryoglobulinaemia	0.022	0.978	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.021	0.979	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.021	0.979	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.021	0.979	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.021	0.979	0.000
D83.9 Common variable immunodeficiency, unspecified	0.020	0.980	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.020	0.980	0.000
D81 Combined immunodeficiencies	0.020	0.980	0.000
D84 Other immunodeficiencies	0.019	0.981	0.000
D82 Immunodeficiency associated with other major defects	0.019	0.981	0.000
D83.8 Other common variable immunodeficiencies	0.017	0.983	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.017	0.983	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.017	0.983	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.017	0.983	0.000
D84.1 Defects in the complement system	0.015	0.985	0.000
M25.7 Osteophyte	0.000	0.985	0.015
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.985	0.015
D81.9 Combined immunodeficiency, unspecified	0.014	0.985	0.000
D81.8 Other combined immunodeficiencies	0.014	0.985	0.000
D81.7 Major histocompatibility complex class II deficiency	0.014	0.985	0.000
D81.6 Major histocompatibility complex class I deficiency	0.014	0.985	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.014	0.985	0.000
D81.4 Nezelof's syndrome	0.014	0.985	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.014	0.985	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.014	0.985	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.014	0.985	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.014	0.985	0.000
D86 Sarcoidosis	0.014	0.986	0.000
M25.77 Osteophyte (Ankle and foot)	0.000	0.986	0.014
M25.74 Osteophyte (Hand)	0.000	0.986	0.014
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.013	0.986	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.013	0.986	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.013	0.986	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.013	0.986	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.013	0.986	0.000
D82.2 Immunodeficiency with short-limbed stature	0.013	0.986	0.000
D82.0 Wiskott-Aldrich syndrome	0.013	0.986	0.000
M25.76 Osteophyte (Lower leg)	0.000	0.986	0.014
D84.8 Other specified immunodeficiencies	0.013	0.986	0.000
M25.79 Osteophyte (Site unspecified)	0.000	0.987	0.013
M25.73 Osteophyte (Forearm)	0.000	0.987	0.013
D82.1 Di George's syndrome	0.012	0.988	0.000
M25.71 Osteophyte (Shoulder region)	0.000	0.988	0.012
D59.1 Other autoimmune haemolytic anaemias	0.012	0.988	0.000
D59 Acquired haemolytic anaemia	0.012	0.988	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.012	0.988	0.000
D86.3 Sarcoidosis of skin	0.012	0.988	0.000
D86.1 Sarcoidosis of lymph nodes	0.011	0.989	0.000
D55-D59 Haemolytic anaemias	0.011	0.989	0.000
M25.70 Osteophyte (Multiple sites)	0.000	0.989	0.011
C71 Malignant neoplasm of brain	0.010	0.990	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.010	0.990	0.000
D84.9 Immunodeficiency, unspecified	0.010	0.990	0.000
D58 Other hereditary haemolytic anaemias	0.010	0.990	0.000
C71.0 Cerebrum, except lobes and ventricles	0.010	0.990	0.000
C71.9 Brain, unspecified	0.010	0.990	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.009	0.991	0.000
C71.4 Occipital lobe	0.009	0.991	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.009	0.991	0.000
C71.8 Overlapping lesion of brain	0.009	0.991	0.000
D59.8 Other acquired haemolytic anaemias	0.009	0.991	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.009	0.991	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.009	0.991	0.000
D59.3 Haemolytic-uraemic syndrome	0.009	0.991	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.009	0.991	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.009	0.991	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.009	0.991	0.000
D86.8 Sarcoidosis of other and combined sites	0.008	0.991	0.000
D57 Sickle-cell disorders	0.008	0.992	0.000
C71.6 Cerebellum	0.008	0.992	0.000
D55 Anaemia due to enzyme disorders	0.008	0.992	0.000
D58.0 Hereditary spherocytosis	0.008	0.992	0.000
C71.2 Temporal lobe	0.008	0.992	0.000
D56 Thalassaemia	0.008	0.992	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.008	0.992	0.000
D58.2 Other haemoglobinopathies	0.008	0.992	0.000
D86.0 Sarcoidosis of lung	0.008	0.992	0.000
C69 Malignant neoplasm of eye and adnexa	0.008	0.992	0.000
C71.7 Brain stem	0.007	0.992	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.007	0.992	0.000
D58.1 Hereditary elliptocytosis	0.007	0.992	0.000
C71.5 Cerebral ventricle	0.007	0.993	0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.007	0.993	0.000
C69.4 Ciliary body	0.007	0.993	0.000
F60.3 Emotionally unstable personality disorder	0.007	0.993	0.000
C71.1 Frontal lobe	0.006	0.993	0.000
D57.1 Sickle-cell anaemia without crisis	0.006	0.994	0.000
C69.2 Retina	0.006	0.994	0.000
C70 Malignant neoplasm of meninges	0.006	0.994	0.000
C69.0 Conjunctiva	0.006	0.994	0.000
C71.3 Parietal lobe	0.006	0.994	0.000
D57.8 Other sickle-cell disorders	0.006	0.994	0.000
D57.3 Sickle-cell trait	0.006	0.994	0.000
D57.2 Double heterozygous sickling disorders	0.006	0.994	0.000
D57.0 Sickle-cell anaemia with crisis	0.006	0.994	0.000
M25.78 Osteophyte (Other)	0.000	0.994	0.006
C69.3 Choroid	0.006	0.994	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.006	0.994	0.000
D55.8 Other anaemias due to enzyme disorders	0.006	0.994	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.006	0.994	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.006	0.994	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.006	0.994	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.006	0.994	0.000
D56.1 Beta thalassaemia	0.006	0.994	0.000
M25.72 Osteophyte (Upper arm)	0.000	0.994	0.006
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.006	0.994	0.000
D56.9 Thalassaemia, unspecified	0.006	0.994	0.000
D56.8 Other thalassaemias	0.006	0.994	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.006	0.994	0.000
D56.2 Delta-beta thalassaemia	0.006	0.994	0.000
D56.0 Alpha thalassaemia	0.006	0.994	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.006	0.994	0.000
C69.8 Overlapping lesion of eye and adnexa	0.006	0.994	0.000
C69.5 Lachrymal gland and duct	0.006	0.994	0.000
C69.1 Cornea	0.006	0.994	0.000
G57.8 Other mononeuropathies of lower limb	0.006	0.994	0.000
C69.6 Orbit	0.006	0.994	0.000
D86.9 Sarcoidosis, unspecified	0.006	0.994	0.000
C69.9 Eye, unspecified	0.006	0.994	0.000
C44.7 Skin of lower limb, including hip	0.005	0.995	0.000
D56.3 Thalassaemia trait	0.005	0.995	0.000
C70.0 Cerebral meninges	0.005	0.995	0.000
D37.6 Liver, gallbladder and bile ducts	0.005	0.995	0.000
C70.9 Meninges, unspecified	0.005	0.995	0.000
C70.1 Spinal meninges	0.005	0.995	0.000
C72.0 Spinal cord	0.005	0.995	0.000
C72.9 Central nervous system, unspecified	0.004	0.995	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.004	0.995	0.000
C72.5 Other and unspecified cranial nerves	0.004	0.995	0.000
C72.4 Acoustic nerve	0.004	0.995	0.000
C72.3 Optic nerve	0.004	0.995	0.000
C72.2 Olfactory nerve	0.004	0.995	0.000
C72.1 Cauda equina	0.004	0.995	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.004	0.996	0.000
F60 Specific personality disorders	0.004	0.996	0.000
D72 Other disorders of white blood cells	0.004	0.996	0.000
I12.9 Hypertensive renal disease without renal failure	0.000	0.996	0.004
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.996	0.004
D72.1 Eosinophilia	0.004	0.996	0.000
M13.09 Polyarthritis, unspecified (Site unspecified)	0.004	0.996	0.000
F60.0 Paranoid personality disorder	0.004	0.996	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.004	0.996	0.000
D75 Other diseases of blood and blood-forming organs	0.004	0.996	0.000
D50-D53 Nutritional anaemias	0.004	0.996	0.000
D60-D64 Aplastic and other anaemias	0.004	0.996	0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.004	0.996	0.000
C45.0 Mesothelioma of pleura	0.004	0.996	0.000
F60.5 Anankastic personality disorder	0.004	0.996	0.000
D62 Acute posthaemorrhagic anaemia	0.004	0.996	0.000
F60.6 Anxious [avoidant] personality disorder	0.003	0.996	0.000
D53 Other nutritional anaemias	0.003	0.996	0.000
D74 Methaemoglobinaemia	0.003	0.997	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.003	0.997	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.003	0.997	0.000
H80.9 Otosclerosis, unspecified	0.000	0.997	0.003
D37.5 Rectum	0.003	0.997	0.000
D53.9 Nutritional anaemia, unspecified	0.003	0.997	0.000
D72.8 Other specified disorders of white blood cells	0.003	0.997	0.000
F60.4 Histrionic personality disorder	0.003	0.997	0.000
F60.1 Schizoid personality disorder	0.003	0.997	0.000
D03.5 Melanoma in situ of trunk	0.003	0.997	0.000
D72.9 Disorder of white blood cells, unspecified	0.003	0.997	0.000
D72.0 Genetic anomalies of leukocytes	0.003	0.997	0.000
F60.7 Dependent personality disorder	0.003	0.997	0.000
Z39.1 Care and examination of lactating mother	0.003	0.997	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.000	0.997	0.003
K14.8 Other diseases of tongue	0.003	0.997	0.000
F60.8 Other specific personality disorders	0.003	0.997	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.003	0.997	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.003	0.997	0.000
F60.2 Dissocial personality disorder	0.003	0.997	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.000	0.997	0.003
F60.9 Personality disorder, unspecified	0.003	0.997	0.000
N75.1 Abscess of Bartholin's gland	0.003	0.997	0.000
D52 Folate deficiency anaemia	0.003	0.997	0.000
R39 Other symptoms and signs involving the urinary system	0.003	0.997	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.003	0.997	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.003	0.997	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.003	0.997	0.000
D75.0 Familial erythrocytosis	0.003	0.997	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.003	0.997	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.000	0.997	0.003
M54.9 Dorsalgia, unspecified	0.000	0.997	0.003
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.997	0.003
D75.1 Secondary polycythaemia	0.003	0.997	0.000
D53.8 Other specified nutritional anaemias	0.003	0.997	0.000
D53.2 Scorbutic anaemia	0.003	0.997	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.003	0.997	0.000
D53.0 Protein deficiency anaemia	0.003	0.997	0.000
D74.9 Methaemoglobinaemia, unspecified	0.003	0.997	0.000
D74.8 Other methaemoglobinaemias	0.003	0.997	0.000
D74.0 Congenital methaemoglobinaemia	0.003	0.997	0.000
D75.2 Essential thrombocytosis	0.003	0.997	0.000
K51.8 Other ulcerative colitis	0.003	0.997	0.000
I84.3 External thrombosed haemorrhoids	0.003	0.997	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.003	0.997	0.000
D61 Other aplastic anaemias	0.003	0.997	0.000
H81.1 Benign paroxysmal vertigo	0.003	0.997	0.000
N42.1 Congestion and haemorrhage of prostate	0.003	0.997	0.000
H66.9 Otitis media, unspecified	0.003	0.997	0.000
D52.8 Other folate deficiency anaemias	0.002	0.998	0.000
D52.1 Drug-induced folate deficiency anaemia	0.002	0.998	0.000
D52.0 Dietary folate deficiency anaemia	0.002	0.998	0.000
R39.2 Extrarenal uraemia	0.002	0.998	0.000
D52.9 Folate deficiency anaemia, unspecified	0.002	0.998	0.000
O32.1 Maternal care for breech presentation	0.000	0.998	0.002
D60.8 Other acquired pure red cell aplasias	0.002	0.998	0.000
D60.1 Transient acquired pure red cell aplasia	0.002	0.998	0.000
D60.0 Chronic acquired pure red cell aplasia	0.002	0.998	0.000
R39.0 Extravasation of urine	0.002	0.998	0.000
K76.9 Liver disease, unspecified	0.000	0.998	0.002
R39.1 Other difficulties with micturition	0.002	0.998	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.002	0.998	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.002	0.998	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.002	0.998	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.002	0.998	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.000	0.998	0.002
Z97.4 Presence of external hearing-aid	0.002	0.998	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.002	0.998	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
B02.2 Zoster with other nervous system involvement	0.002	0.998	0.000
M24.23 Disorder of ligament (Forearm)	0.002	0.998	0.000
M13.0 Polyarthritis, unspecified	0.002	0.998	0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.002	0.998	0.000
D61.9 Aplastic anaemia, unspecified	0.002	0.998	0.000
D73 Diseases of spleen	0.002	0.998	0.000
B44.1 Other pulmonary aspergillosis	0.000	0.998	0.002
M24.27 Disorder of ligament (Ankle and foot)	0.002	0.998	0.000
D61.8 Other specified aplastic anaemias	0.002	0.998	0.000
D61.3 Idiopathic aplastic anaemia	0.002	0.998	0.000
D61.2 Aplastic anaemia due to other external agents	0.002	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.000	0.998	0.002
L52 Erythema nodosum	0.000	0.998	0.002
M24.21 Disorder of ligament (Shoulder region)	0.002	0.998	0.000
G57.0 Lesion of sciatic nerve	0.002	0.998	0.000
L28.0 Lichen simplex chronicus	0.000	0.998	0.002
D73.1 Hypersplenism	0.002	0.998	0.000
G53.0 Postzoster neuralgia	0.002	0.998	0.000
L29.9 Pruritus, unspecified	0.002	0.998	0.000
D37.9 Digestive organ, unspecified	0.002	0.998	0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.000	0.998	0.002
D73.4 Cyst of spleen	0.002	0.998	0.000
G57.6 Lesion of plantar nerve	0.002	0.998	0.000
I72.4 Aneurysm of artery of lower extremity	0.002	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.002	0.998	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.002	0.998	0.000
G57 Mononeuropathies of lower limb	0.002	0.998	0.000
K51.4 Pseudopolyposis of colon	0.002	0.998	0.000
K63.0 Abscess of intestine	0.000	0.998	0.002
D37.0 Lip, oral cavity and pharynx	0.002	0.998	0.000
M82.1 Osteoporosis in endocrine disorders	0.002	0.998	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.002	0.998	0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.002	0.998	0.000
R81 Glycosuria	0.000	0.998	0.002
D03.4 Melanoma in situ of scalp and neck	0.002	0.998	0.000
D37.3 Appendix	0.002	0.998	0.000
I31.9 Disease of pericardium, unspecified	0.002	0.998	0.000
M13.08 Polyarthritis, unspecified (Other)	0.002	0.998	0.000
M13.07 Polyarthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
M13.06 Polyarthritis, unspecified (Lower leg)	0.002	0.998	0.000
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M13.04 Polyarthritis, unspecified (Hand)	0.002	0.998	0.000
M13.03 Polyarthritis, unspecified (Forearm)	0.002	0.998	0.000
M13.02 Polyarthritis, unspecified (Upper arm)	0.002	0.998	0.000
M13.01 Polyarthritis, unspecified (Shoulder region)	0.002	0.998	0.000
D61.0 Constitutional aplastic anaemia	0.002	0.998	0.000
M24.2 Disorder of ligament	0.002	0.998	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.000	0.998	0.002
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.002	0.998	0.000
D51 Vitamin B12 deficiency anaemia	0.002	0.998	0.000
D73.9 Disease of spleen, unspecified	0.002	0.998	0.000
D73.2 Chronic congestive splenomegaly	0.002	0.998	0.000
M24.24 Disorder of ligament (Hand)	0.002	0.998	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
D61.1 Drug-induced aplastic anaemia	0.002	0.998	0.000
D37.1 Stomach	0.002	0.998	0.000
F05.9 Delirium, unspecified	0.000	0.998	0.002
D76.3 Other histiocytosis syndromes	0.001	0.998	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.998	0.002
D51.8 Other vitamin B12 deficiency anaemias	0.002	0.998	0.000
D03 Melanoma in situ	0.002	0.998	0.000
G57.4 Lesion of medial popliteal nerve	0.002	0.998	0.000
G57.2 Lesion of femoral nerve	0.002	0.998	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.002	0.998	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.002	0.998	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.002	0.998	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.002	0.998	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.002	0.998	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.002	0.998	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.002	0.998	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.002	0.998	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.002	0.998	0.000
D11.0 Parotid gland	0.002	0.998	0.000
D73.5 Infarction of spleen	0.002	0.998	0.000
K09.0 Developmental odontogenic cysts	0.000	0.998	0.002
D73.3 Abscess of spleen	0.001	0.998	0.000
M24.29 Disorder of ligament (Site unspecified)	0.001	0.998	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.001	0.998	0.000
M24.22 Disorder of ligament (Upper arm)	0.001	0.998	0.000
M24.20 Disorder of ligament (Multiple sites)	0.001	0.998	0.000
D51.2 Transcobalamin II deficiency	0.001	0.998	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.001	0.998	0.000
C45 Mesothelioma	0.002	0.998	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.002	0.998	0.000
H20.8 Other iridocyclitis	0.002	0.998	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.998	0.002
M34.8 Other forms of systemic sclerosis	0.000	0.998	0.002
I21.3 Acute transmural myocardial infarction of unspecified site	0.002	0.998	0.000
I72.3 Aneurysm of iliac artery	0.002	0.998	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.002	0.998	0.000
B02.8 Zoster with other complications	0.001	0.998	0.000
D37.2 Small intestine	0.001	0.998	0.000
Z39 Postpartum care and examination	0.002	0.998	0.000
C45.7 Mesothelioma of other sites	0.001	0.998	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.000	0.998	0.002
D03.9 Melanoma in situ, unspecified	0.001	0.998	0.000
D03.0 Melanoma in situ of lip	0.001	0.998	0.000
K72.9 Hepatic failure, unspecified	0.000	0.998	0.002
M24.28 Disorder of ligament (Other)	0.001	0.998	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.001	0.998	0.000
F25.9 Schizoaffective disorder, unspecified	0.001	0.998	0.000
G57.9 Mononeuropathy of lower limb, unspecified	0.001	0.998	0.000
H90.5 Sensorineural hearing loss, unspecified	0.001	0.999	0.000
L92.0 Granuloma annulare	0.000	0.999	0.001
M75.5 Bursitis of shoulder	0.000	0.999	0.001
D64 Other anaemias	0.001	0.999	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.001	0.999	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
D73.8 Other diseases of spleen	0.001	0.999	0.000
Z01.9 Special examination, unspecified	0.000	0.999	0.001
D03.8 Melanoma in situ of other sites	0.001	0.999	0.000
N49.8 Inflammatory disorders of other specified male genital organs	0.001	0.999	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.001	0.999	0.000
B02.1 Zoster meningitis	0.001	0.999	0.000
C45.2 Mesothelioma of pericardium	0.001	0.999	0.000
C45.1 Mesothelioma of peritoneum	0.001	0.999	0.000
D37.7 Other digestive organs	0.001	0.999	0.000
G57.5 Tarsal tunnel syndrome	0.001	0.999	0.000
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.000	0.999	0.001
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.001	0.999	0.000
S81.0 Open wound of knee	0.001	0.999	0.000
Z39.0 Care and examination immediately after delivery	0.001	0.999	0.000
B02 Zoster [herpes zoster]	0.001	0.999	0.000
Z81.8 Family history of other mental and behavioural disorders	0.000	0.999	0.001
H80 Otosclerosis	0.000	0.999	0.001
G57.3 Lesion of lateral popliteal nerve	0.001	0.999	0.000
R82.7 Abnormal findings on microbiological examination of urine	0.000	0.999	0.001
T83.1 Mechanical complication of other urinary devices and implants	0.001	0.999	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.001	0.999	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.001	0.999	0.000
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.000	0.999	0.001
K37 Unspecified appendicitis	0.001	0.999	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.000	0.999	0.001
Z90.2 Acquired absence of lung [part of]	0.000	0.999	0.001
I12 Hypertensive renal disease	0.000	0.999	0.001
D03.3 Melanoma in situ of other and unspecified parts of face	0.001	0.999	0.000
D64.4 Congenital dyserythropoietic anaemia	0.001	0.999	0.000
D64.3 Other sideroblastic anaemias	0.001	0.999	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.001	0.999	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.001	0.999	0.000
L28.1 Prurigo nodularis	0.000	0.999	0.001
D63.1 Anaemia in other chronic diseases classified elsewhere	0.001	0.999	0.000
D64.0 Hereditary sideroblastic anaemia	0.001	0.999	0.000
I72.1 Aneurysm of artery of upper extremity	0.001	0.999	0.000
I84.5 External haemorrhoids without complication	0.001	0.999	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.999	0.001
B02.7 Disseminated zoster	0.001	0.999	0.000
B02.0 Zoster encephalitis	0.001	0.999	0.000
B50.9 Plasmodium falciparum malaria, unspecified	0.001	0.999	0.000
H80.8 Other otosclerosis	0.000	0.999	0.001
H80.2 Cochlear otosclerosis	0.000	0.999	0.001
H80.1 Otosclerosis involving oval window, obliterative	0.000	0.999	0.001
N64.4 Mastodynia	0.001	0.999	0.000
S56.7 Injury of multiple muscles and tendons at forearm level	0.001	0.999	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.000	0.999	0.001
D67 Hereditary factor IX deficiency	0.001	0.999	0.000
I72 Other aneurysm	0.001	0.999	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.001	0.999	0.000
R25.3 Fasciculation	0.001	0.999	0.000
Z49.1 Extracorporeal dialysis	0.000	0.999	0.001
S56 Injury of muscle and tendon at forearm level	0.001	0.999	0.000
S92.00 Fracture of calcaneus (closed)	0.001	0.999	0.000
M90.7 Fracture of bone in neoplastic disease	0.001	0.999	0.000
X69.9 Unspecified place	0.001	0.999	0.000
Z39.2 Routine postpartum follow-up	0.001	0.999	0.000
L28 Lichen simplex chronicus and prurigo	0.000	0.999	0.001
C16.6 Greater curvature of stomach, unspecified	0.001	0.999	0.000
G57.1 Meralgia paraesthetica	0.001	0.999	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.000	0.999	0.001
D03.7 Melanoma in situ of lower limb, including hip	0.001	0.999	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.999	0.001
L50.1 Idiopathic urticaria	0.001	0.999	0.000
N84.2 Polyp of vagina	0.000	0.999	0.001
M24.26 Disorder of ligament (Lower leg)	0.001	0.999	0.000
D02.0 Larynx	0.001	0.999	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.001	0.999	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.001	0.999	0.000
N02.8 Other	0.001	0.999	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.001	0.999	0.000
B02.9 Zoster without complication	0.001	0.999	0.000
E23.0 Hypopituitarism	0.000	0.999	0.001
I72.8 Aneurysm of other specified arteries	0.001	0.999	0.000
I72.2 Aneurysm of renal artery	0.001	0.999	0.000
S56.2 Injury of other flexor muscle and tendon at forearm level	0.001	0.999	0.000
S56.0 Injury of flexor muscle and tendon of thumb at forearm level	0.001	0.999	0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.001	0.999	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.001	0.999	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.001	0.999	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.001	0.999	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.001	0.999	0.000
D64.8 Other specified anaemias	0.001	0.999	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.000	0.999	0.001
L28.2 Other prurigo	0.000	0.999	0.001
W29.9 Unspecified place	0.001	0.999	0.000
I72.9 Aneurysm of unspecified site	0.001	0.999	0.000
T75.4 Effects of electric current	0.001	0.999	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.000	0.999	0.001
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.001	0.999	0.000
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust	0.001	0.999	0.000
Z03.5 Observation for other suspected cardiovascular diseases	0.000	0.999	0.001
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.001	0.999	0.000
S56.20 Unspecified injury of other flexor muscle, fascia and tendon at forearm level	0.001	0.999	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.001	0.999	0.000
J01.9 Acute sinusitis, unspecified	0.000	0.999	0.001
B44 Aspergillosis	0.000	0.999	0.001
C79.2 Secondary malignant neoplasm of skin	0.001	0.999	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.999	0.001
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.999	0.001
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.001	0.999	0.000
R80 Isolated proteinuria	0.000	0.999	0.001
B44.8 Other forms of aspergillosis	0.000	0.999	0.001
B44.7 Disseminated aspergillosis	0.000	0.999	0.001
B44.2 Tonsillar aspergillosis	0.000	0.999	0.001
B44.0 Invasive pulmonary aspergillosis	0.000	0.999	0.001
H53.8 Other visual disturbances	0.001	0.999	0.000
J86.9 Pyothorax without fistula	0.000	0.999	0.001
J86.0 Pyothorax with fistula	0.000	0.999	0.001
Z94.7 Corneal transplant status	0.000	0.999	0.001
F60-F69 Disorders of adult personality and behaviour	0.001	0.999	0.000
N75.9 Disease of Bartholin's gland, unspecified	0.001	0.999	0.000
S56.5 Injury of other extensor muscle and tendon at forearm level	0.001	0.999	0.000
X61.2 School, other institution and public administrative area	0.001	0.999	0.000
X69.0 Home	0.001	0.999	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.001	0.999	0.000
F65 Disorders of sexual preference	0.001	0.999	0.000
F63 Habit and impulse disorders	0.001	0.999	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.001	0.999	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.001	0.999	0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
B44.9 Aspergillosis, unspecified	0.000	0.999	0.001
H20.1 Chronic iridocyclitis	0.001	0.999	0.000
J34.3 Hypertrophy of nasal turbinates	0.001	0.999	0.000
J38.0 Paralysis of vocal cords and larynx	0.001	0.999	0.000
M11.2 Other chondrocalcinosis	0.000	0.999	0.001
Q25.4 Other congenital malformations of aorta	0.001	0.999	0.000
T42.1 Iminostilbenes	0.001	0.999	0.000
F68 Other disorders of adult personality and behaviour	0.001	0.999	0.000
M11.29 Other chondrocalcinosis (Site unspecified)	0.000	0.999	0.001
M11.28 Other chondrocalcinosis (Other)	0.000	0.999	0.001
M11.27 Other chondrocalcinosis (Ankle and foot)	0.000	0.999	0.001
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.000	0.999	0.001
M11.24 Other chondrocalcinosis (Hand)	0.000	0.999	0.001
M11.23 Other chondrocalcinosis (Forearm)	0.000	0.999	0.001
M11.22 Other chondrocalcinosis (Upper arm)	0.000	0.999	0.001
M11.21 Other chondrocalcinosis (Shoulder region)	0.000	0.999	0.001
M11.20 Other chondrocalcinosis (Multiple sites)	0.000	0.999	0.001
M40.24 Other and unspecified kyphosis (Thoracic region)	0.000	0.999	0.001
B02.3 Zoster ocular disease	0.001	0.999	0.000
C45.9 Mesothelioma, unspecified	0.001	0.999	0.000
F62.9 Enduring personality change, unspecified	0.001	0.999	0.000
F62.8 Other enduring personality changes	0.001	0.999	0.000
F62.1 Enduring personality change after psychiatric illness	0.001	0.999	0.000
F62.0 Enduring personality change after catastrophic experience	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations